AC MF_04046; DC Protein; auto c? TR HAMAP; MF_00148; -; 1; level=0 XX Names: HSV_UNG XX ID UNG DE RecName: Full=Uracil-DNA glycosylase; DE Short=UDG; DE EC=3.2.2.27; DE AltName: Full=UNG; XX CC -!- FUNCTION: Excises uracil residues from the DNA which can arise as a CC result of misincorporation of dUMP residues by DNA polymerase or CC deamination of cytosines. Therefore may reduce deleterious uracil CC incorporation into the viral genome, particularly in terminally CC differentiated cells which lack DNA repair enzymes. CC -!- CATALYTIC ACTIVITY: CC Reaction=Hydrolyzes single-stranded DNA or mismatched double-stranded CC DNA and polynucleotides, releasing free uracil.; EC=3.2.2.27; CC -!- SUBCELLULAR LOCATION: Host nucleus. CC -!- SIMILARITY: Belongs to the uracil-DNA glycosylase (UDG) superfamily. CC UNG family. XX DR PROSITE; PS00130; U_DNA_GLYCOSYLASE; 1; trigger=no DR Pfam; PF03167; UDG; 1; trigger=no DR NCBIfam; TIGR00628; ung; 1; trigger=no XX KW DNA damage KW DNA repair KW Host nucleus KW Hydrolase XX GO GO:0042025; C:host cell nucleus GO GO:0004844; F:uracil DNA N-glycosylase activity GO GO:0006284; P:base-excision repair XX FT From: UNG_ECOLI (P12295) FT ACT_SITE 64 FT /note="Proton acceptor" FT Condition: D XX Size: 204-362; Related: None; Template: P10186; P12295; Scope: Viruses; Herpesviridae Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: None XX # Revision 1.7 2023/06/01 //