AC   MF_04096;
DC   Protein; auto
TR   HAMAP; MF_04096; -; 1; level=0
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Names: BETA_CORONA_NCAP
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ID   NCAP
DE   RecName: Full=Nucleoprotein;
DE   AltName: Full=Nucleocapsid protein;
DE            Short=NC;
DE            Short=Protein N;
GN   Name=N;
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CC   -!- FUNCTION: Packages the positive strand viral genome RNA into a helical
CC       ribonucleocapsid (RNP) and plays a fundamental role during virion
CC       assembly through its interactions with the viral genome and membrane
CC       protein M. Plays an important role in enhancing the efficiency of
CC       subgenomic viral RNA transcription as well as viral replication.
CC   -!- SUBUNIT: Homooligomer. Both monomeric and oligomeric forms interact
CC       with RNA. Interacts with protein M. Interacts with NSP3; this
CC       interaction serves to tether the genome to the newly translated
CC       replicase-transcriptase complex at a very early stage of infection.
CC   -!- SUBCELLULAR LOCATION: Virion. Host endoplasmic reticulum-Golgi
CC       intermediate compartment. Host Golgi apparatus. Note=Located inside the
CC       virion, complexed with the viral RNA. Probably associates with ER-
CC       derived membranes where it participates in viral RNA synthesis and
CC       virus budding.
CC   -!- PTM: ADP-ribosylated. The ADP-ribosylation is retained in the virion
CC       during infection.
CC   -!- PTM: Phosphorylated on serine and threonine residues.
CC   -!- SIMILARITY: Belongs to the betacoronavirus nucleocapsid protein family.
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DR   Pfam; PF00937; Corona_nucleoca; 1; trigger=no
DR   PIRSF; PIRSF003888; Corona_nucleocap; 1; trigger=no
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KW   ADP-ribosylation
KW   Host Golgi apparatus
KW   Phosphoprotein
KW   Ribonucleoprotein
KW   RNA-binding
KW   Transcription
KW   Transcription regulation
KW   Viral nucleoprotein
KW   Virion
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GO   GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment
GO   GO:0044177; C:host cell Golgi apparatus
GO   GO:0019013; C:viral nucleocapsid
GO   GO:0003723; F:RNA binding
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FT   From: NCAP_CVMA5 (P03416)
FT   REGION          56..197
FT                   /note="RNA-binding"
FT   REGION          267..383
FT                   /note="Dimerization"
FT   MOD_RES         162
FT                   /note="Phosphoserine; by host"
FT   Condition: S
FT   MOD_RES         170
FT                   /note="Phosphoserine; by host"
FT   Condition: S
FT   MOD_RES         177
FT                   /note="Phosphothreonine; by host"
FT   Condition: T
FT   MOD_RES         389
FT                   /note="Phosphoserine; by host"
FT   Condition: S
FT   MOD_RES         424
FT                   /note="Phosphoserine; by host"
FT   Condition: S
FT   MOD_RES         428
FT                   /note="Phosphothreonine; by host"
FT   Condition: T
FT   From: NCAP_SARS (P59595)
FT   MOD_RES         177
FT                   /note="Phosphoserine; by host"
FT   Condition: S
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Size: 411-468;
Related: None;
Template: P03416; P59595;
Scope:
 Viruses; Betacoronavirus
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.4 2021/03/25
//