AC   MF_04138;
DC   Protein; auto
TR   HAMAP; MF_04138; -; 1; level=0
XX
Names: TMP_LAMBDA
XX
ID   TMP
case <OC:Lambdavirus>
DE   RecName: Full=Tape measure protein;
DE            Short=TMP;
DE   AltName: Full=Gene product H;
DE            Short=gpH;
DE   AltName: Full=Minor tail protein H;
DE   Contains:
DE     RecName: Full=Entry protein H*;
GN   Name=H;
else
DE   RecName: Full=Tape measure protein;
DE            Short=TMP;
end case
XX
case <OC:Lambdavirus>
CC   -!- FUNCTION: Serves as a ruler that controls the length of tail by
CC       stopping the tail tube polymerization and is probably released from the
CC       tail shaft during infection to facilitate DNA translocation into the
CC       host cell. Assembles into a multimeric linear form probably arranged as
CC       a six-stranded coil of alpha-helices and stabilized by the covering
CC       tail assembly proteins G and GT. Its C-terminus fixes the tail tip
CC       complex (J, I, L, K), thereby forming the tail assembly initiator
CC       complex. Tail tube proteins polymerize around the tape measure protein,
CC       displacing the tail assembly proteins G and GT. When the tail reaches
CC       the length specified by the tape measure protein, it stops and becomes
CC       capped by the tail terminator protein. Upon tail assembly, tape measure
CC       protein is cleaved into a form called H*, that plays a role later
CC       during virion entry in a new cell. Once assembled, the virion is
CC       released and can infect new cell by binding to the entry receptor.
CC       After opening of a pore on the external membrane, the entry protein H*
CC       protein is probably released in the periplasmic space for successfull
CC       DNA injection.
CC   -!- SUBUNIT: Interacts with the tail initiator complex presumably through
CC       its C-terminus domain. Interacts with the tail assembly protein G.
CC       Interacts with the tail assembly protein GT.
CC   -!- SUBCELLULAR LOCATION: Virion. Note=There are 6 copies of entry protein
CC       H* per mature phage.
CC   -!- PTM: Cleaved into mature protein H* by an unidentified protease.
else
CC   -!- FUNCTION: Serves as a ruler that controls the length of tail by
CC       stopping the tail tube polymerization and is probably released from the
CC       tail shaft during infection to facilitate DNA translocation into the
CC       host cell. Assembles into a multimeric linear form probably arranged as
CC       a coil of alpha-helices and stabilized by the covering tail assembly
CC       proteins. Its C-terminus fixes the tail tip complex, thereby forming
CC       the tail assembly initiator complex. Tail tube proteins polymerize
CC       around the tail measure protein, displacing the tail assembly proteins.
CC       When the tail reaches the length specified by the tape measure protein,
CC       it stops and becomes capped by the tail terminator protein.
CC   -!- SUBUNIT: Interacts with the tail initiator complex presumably through
CC       its C-terminus domain. Interacts with the tail assembly proteins.
CC   -!- SUBCELLULAR LOCATION: Virion.
end case
CC   -!- SIMILARITY: Belongs to the Lambdavirus tape measure protein family.
XX
DR   Pfam; PF09718; Tape_meas_lam_C; 1; trigger=no
DR   Pfam; PF06791; TMP_2; 1; trigger=no
DR   NCBIfam; TIGR01541; tape_meas_lam_C; 1; trigger=no
DR   General; Coiled_coil; -; 0-unlimited; trigger=yes
XX
KW   Viral genome ejection through host cell envelope
case <OC:Lambdavirus>
KW   Viral long flexible tail ejection system
end case
KW   Viral penetration into host cytoplasm
KW   Viral release from host cell
KW   Viral tail assembly
KW   Viral tail protein
KW   Virion
KW   Virus entry into host cell
XX
GO   GO:0098003; P:viral tail assembly
GO   GO:0098015; C:virus tail
XX
FT   From: TMP_LAMBD (P03736)
FT   CHAIN           Nter..Cter
FT                   /note="Tape measure protein"
case <OC:Lambdavirus>
FT   CHAIN           ?..Cter
FT                   /note="Entry protein H*"
end case
XX
Size: 800-1200;
Related: None;
Template: P03736;
Scope:
 Viruses
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2023/06/01
//