AC   MF_04164;
DC   Protein; auto
TR   HAMAP; MF_04164; -; 1; level=0
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Names: T4_Sigma-like factor
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ID   SIGML
DE   RecName: Full=RNA polymerase sigma-like factor;
DE   AltName: Full=Promoter specificity factor;
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CC   -!- FUNCTION: Plays a role in the transcription of the viral late genes by
CC       acting as a late promoter recognition subunit. Associates with host RNA
CC       polymerase (RNAP) core and thus replaces the host sigma-70/rpoD subunit
CC       in the complex. May also play a role in DNA packaging by interacting
CC       with the terminase subunit gp17.
CC   -!- SUBUNIT: Interacts with the host RNA polymerase catalytic core formed
CC       by RpoA, RpoB, RpoC and RpoZ to form the RNAP-gp55 holoenzyme. Part of
CC       the transcription activation complex containing host RNAP, the viral
CC       RNA polymerase sigma-like factor, the late transcription coactivator,
CC       and the sliding clamp. Interacts with the terminase large subunit; this
CC       interaction may load the terminase onto DNA for packaging.
CC   -!- SIMILARITY: Belongs to the Tevenvirinae RNA polymerase sigma-like
CC       factor family.
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DR   Pfam; PF04542; Sigma70_r2; 0-1; trigger=no
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KW   DNA-binding
KW   Host-virus interaction
KW   Nucleotidyltransferase
KW   Sigma factor
KW   Viral transcription
KW   Transcription regulation
KW   Transferase
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GO   GO:0016987; F:sigma factor activity
GO   GO:0003677; F:DNA binding
GO   GO:0019086; P:late viral transcription
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FT   From: SIGML_BPT4 (P04524)
FT   DNA_BIND        114
FT   Condition: [RK]
FT   REGION          13..113
FT                   /note="Interaction with host RNAP core and recognition of
FT                   the promoter specific element"
FT   SITE            70
FT                   /note="Interaction with host RNAP"
FT   Optional; Condition: [DE]
FT   SITE            74
FT                   /note="Interaction with host RNAP"
FT   Optional; Condition: [DE]
FT   SITE            77
FT                   /note="Interaction with host RNAP"
FT   Optional; Condition: [DE]
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Size: 134-214;
Related: None;
Template: P04524;
Scope:
 Viruses
Fusion:
 Nter: None
 Cter: None
Duplicate: in BPT4, 9CAUD, 9VIRU
Plasmid: None
Comments: None
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# Revision 1.2 2021/04/20
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