AC   MF_04165;
DC   Protein; auto
TR   HAMAP; MF_04165; -; 1; level=0
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Names: T4_TRANSCR_COACT
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ID   LTACT
DE   RecName: Full=Late transcription coactivator;
DE   AltName: Full=RNA polymerase-associated protein Gp33;
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CC   -!- FUNCTION: Activates transcription at late promoters when the sliding
CC       clamp is present. Binds to both the host RNA polymerase (RNAP) and the
CC       upstream dsDNA.
CC   -!- SUBUNIT: Interacts with the beta subunit of host RNAP RpoB (via flap
CC       domain). Part of the transcription activation complex containing host
CC       RNAP, the viral RNA polymerase sigma-like factor, the coactivator gp33,
CC       and the sliding clamp.
CC   -!- DOMAIN: The C-terminus is involved in transcriptional enhancement.
CC   -!- SIMILARITY: Belongs to the Tevenvirinae late transcription coactivator
CC       family.
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DR   Pfam; PF16805; Trans_coact; 1; trigger=no
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GO   GO:0140537; F:transcription regulator activator activity
GO   GO:0019086; P:late viral transcription
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FT   From: LTACT_BPT4 (P13338)
FT   REGION          62..92
FT                   /note="Interaction with host RNAP"
FT   REGION          106..112
FT                   /note="Involved in transcriptional enhancement"
FT   Condition: [NQS]-[NST]-L-[DE]-[DFGI]-[FL]-x
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Size: 60-300;
Related: None;
Template: P13338;
Scope:
 Viruses
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.3 2021/04/27
//