CLUSTAL format seed alignment for MF_00052_A
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Features found in the protein:
- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
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RNH2_AERPE -------------------MGIVVGVDEAGRGSLVGDLVVAGFAVEEARLGELQSLGVRD
RNH2_NATPD -------------------MTPLVGVDEAGKGPVVGSMFVAAVRAPTEALPD----GIDD
RNH2_HALMA ---------------------MRFGVDEAGKGPVLGSMFAAAVRADPAALPG----GVGD
RNH2_HALSA --------------------MARFGVDEAGKGPVLGSMFAAAVAGDPAAVPD----GVAD
RNH2_METKA -------------------MSGVMGIDEAGRGPVFGPMVVAGVLAPKREL----GLGARD
RNH2_PICTO --------------------MCVCGIDEAGRGPVIGPMVMAMVCADDI------NFYVND
RNH2_THEAC ----------------MTESERQCGIDEAGRGPVIGPMVISLVCCDLS---FLKEIRVKD
RNH2_THEVO -----------------MHEEVQCGIDEAGRGPVIGPMVISIVCCKEE---YLREIGVKD
RNH2_METST --------------MILDDESQILGIDEAGRGSVIGPLVIGGVLMKKKKIRFLNRIGVKD
RNH2_METMP MSEDINNNLNNSDNSNGSNEKIIVGLDEAGRGPVLGPMVIASVKIDEKNLYKLNDLELKD
RNH2_METJA --------------------MIIIGIDEAGRGPVLGPMVVCAFAIEKEREEELKKLGVKD
RNH2_SULAC --------------------MILVGIDEAGRGSLIGPMVVAGVAIDSNFLKFLSEIGVKD
RNH2_SACS2 ---------------------MRVGIDEAGRGALIGPMIVAGVVISDTKLKFLKGIGVKD
RNH2_SULTO --------------------MIVVGIDEAGRGSLIGPMIVAGVAIKNDRLKFLKNIGVKD
RNH2_PYRAE ---------------------MIGGIDEAGRGPVIGPMVIAIVVGESD---DMIKIGVRD
RNH2_NANEQ --------------------MRYGGVDEAGRGPIIGPMVIALVIGDSG---YLKELGVKD
RNH2_METHJ ---------------------MICGVDEAGKGSVLGPMVVAAVGCTD--MDDLIALGVAD
RNH2_METBF --------------------MMIAGIDEAGKGPVIGPMCIGGVKIEESRAHILKVLGVAD
RNH2_METAC --------------------MMIAGIDEAGKGPVIGPMCIGGVKIEESRAHILKVLGVAD
RNH2_METMA --------------------MMIAGIDEAGKGPVIGPMCIGGVKIDESKAHILKVLGVAD
RNH2_THEKO --------------------MKIAGIDEAGRGPVIGPMVIAAVVVDENSLPKLEELKVRD
RNH2_PYRFU --------------------MKIGGIDEAGRGPAIGPLVVATVVVDEKNIEKLRNIGVKD
RNH2_PYRAB --------------------MKVAGADEAGRGPVIGPLVIVAAVVEEDKIRSLTKLGVKD
RNH2_PYRHO --------------------MKVAGVDEAGRGPVIGPLVIGVAVIDEKNIERLRDIGVKD
RNH2_METTH --------------------MKVLGIDEAGRGPVIGPLVVAGVMIPERKFSILRKMGVKD
RNH2_ARCFU ---------------------MKAGIDEAGKGCVIGPLVVAGVACSDE--DRLRKLGVKD
* ****:* .* : *
RNH2_AERPE SKQLSPAARVELYREISGVGF--FTVEAIR--PWEIDGE-----NINILVTKAVEEIVSR
RNH2_NATPD SKRLTDDRREALADRLRDADRIDVAVVECQ--PADIDDA-----NMNDLTVAAHAAALDG
RNH2_HALMA SKDIRPERRERLAKEIRESADA-VGIAEISVERIDADET-----DMNTLTVEGQAEALSA
RNH2_HALSA SKRLSADRRAELDDRVRASMR--VGVAEVPVDRIDDPET-----DMNTLTVAAQADALGR
RNH2_METKA SKELTRSARRRLIRALMSDERLRVDLRIVW--PWEIDEE-----GVAKAEFEAIRELVR-
RNH2_PICTO SKLLTRNKRSLIFNDVSGLYHK-YYIIN----PAEIDDAVKKH-SLNNLEEQYAEKLIL-
RNH2_THEAC SKALTRKRRSELFEKIMGRCSVRYRILH----PKDLNRMMAAE-SLNKIEEDEIVDLLR-
RNH2_THEVO SKMLSRKRREYLFDKITKNCA--YSYVVVS--PETLNKDMASE-SLNKIEENYILELLS-
RNH2_METST SKQLNMKKRTIISRKIKKIAQ--FKTIIIP--AHTIDEKRNNDINLNEIETEGMEEIIK-
RNH2_METMP SKQLSKKKREELYIIINEMCD--VEKIVID--PETIDKQMEII-NLNKIELSAFSKLSNH
RNH2_METJA SKELTKNKRAYLKKLLENLGYVEKRILE----AEEINQLMNSI-NLNDIEINAFSKVAKN
RNH2_SULAC SKKLTRKKREYLFGVILEYSYA-ISLVKAY--PEEIDSE-----NLNEITYRAMIQIIHS
RNH2_SACS2 SKQLTRERREKLFDIVANTVEA-FTVVKVF--PYEIDNY-----NLNDLTYDAVSKIILS
RNH2_SULTO SKQLTRNRREKLFDIICSYSEG-FTIVKVS--PEEIDSE-----NLNELTYKAMIKIIYS
RNH2_PYRAE SKRLSPGAREAVYEKILRVAAC-VNYVVIE--PAEIDAYVSRG-MLNALELKYTAQLIN-
RNH2_NANEQ SKLLTKEQREELFNEIVKNSLVKYEIVS----PSLIDRY-----NLNELEAKVTANLINS
RNH2_METHJ SKKLSSKSREKISADIKAQFP--FSIVIRT--AHDIDELRRTM-TMNEIVARSHAEALI-
RNH2_METBF SKKLTPKKREQLAAQIKKHADG-FFVLEVS--PSQIDELRKIM-TMNEIMVVCFSKVLE-
RNH2_METAC SKKLTPKKREQLASQIKKHADG-FFILEIT--PAQIDELRKIM-SMNEIMVICFAKVLE-
RNH2_METMA SKKLTPKKREQLASQIKKHADG-YFIFEVS--PSQIDELRKIM-SMNEIMVVCFAKVLE-
RNH2_THEKO SKKLTPKRREKLFNEILGVLDD-YVILELP--PDVIGSREG---TLNEFEVENFAKALNS
RNH2_PYRFU SKQLTPHERKNLFSQITSIADD-YKIVIVS--PEEIDNRSG---TMNELEVEKFALALNS
RNH2_PYRAB SKQLTPAQREKLFDEIVKVLDD-YSVVIVS--PQDIDGRKG---SMNELEVENFVKALNS
RNH2_PYRHO SKQLTPGQREKLFSKLIDILDD-YYVLLVT--PKEIDERHH---SMNELEAEKFVVALNS
RNH2_METTH SKKLTPERRRFLARKIRRIAR--VFTVKIS--ASDIDRMRERGFNLNEIEKIAIKRIIP-
RNH2_ARCFU SKKLSQGRREELAEEIRKICR--TEVLKVS--PENLDERMAAK-TINEILKECYAEIIL-
** : * : : :
RNH2_AERPE IVSYLG--VHPSLVVVDKYGDVQGLRLALTRLGIEP---------RSILVEEKADSRYPV
RNH2_NATPD VA------ASGETVLCDAG-DVDAGRFADRVAAAAT-------LDVSVAAEHGADGSDDL
RNH2_HALMA VAR------DGLSGTVDAG-DTDAARFGRRVADAVD-------TDVAVTAEHGADETDSL
RNH2_HALSA VV------ADGMAGYVDAG-DVNEQRFGRRVANRVA-------ADVAVTAEHGADDEYDL
RNH2_METKA --R-----AMPDEVILDKPGNYSPERLRRELDLPEG---------INLIAEERADAKYEV
RNH2_PICTO --K-----AECEKIYIDCF-DVNESRLERILKDRTG---------KEVICRHHADRDIKI
RNH2_THEAC --------YADDLVYIDCY-DVIEERAQEIIQMRSG---------RQVVCKHKADAIFPA
RNH2_THEVO --------KAEGIVYIDCF-DVIEERAEKYIREKSG---------KEVVCKHKADSIYPA
RNH2_METST --I-----MKPNACYIDCI-DVRENRFHDKIQKINP--------NMTVVTEHKADETYKI
RNH2_METMP FIRE----NDNISIYIDAC-SSSEQSFSNQFKAKLI------NKNVEIIAEHKADENYKI
RNH2_METJA LIEKLNIRDDEIEIYIDAC-STNTKKFEDSFKDKIEDIIKERNLNIKIIAEHKADAKYPV
RNH2_SULAC MSV-----YNPSIVTVDKV--GNASAVEREIININS----------SPRVENNADVKYVE
RNH2_SACS2 LSS-----FNPEIVTVD---KVGDEKPVIELINKLG-------YKSNVV--HKADVLFVE
RNH2_SULTO LVE-----FKPIRISID---KVGNTKVVEQEIIKLG-------MEPNIV--TNADVYFVE
RNH2_PYRAE --L-----CPAEYYYVDSP-DVNPKRYESGLVFATG---------KRVIALHKGEAV-PQ
RNH2_NANEQ I-E-----DEISHIVIDSP-E-RPENYKLRILKYLK-------KRVKIITKNKGEED-PL
RNH2_METHJ --P-----LNCTCAYVDAC-DVSEERYEETVSSFSP-------PDCTIVARHKADSLFPP
RNH2_METBF --Q-----LKPDLLYADAA-DVNAERFATNIRKQYSKTNPDHAKEIEIISMHQADATYPV
RNH2_METAC --Q-----LKPDIVYADAA-DVKAERFAENLRRQYAKTNPAHAKKIEIISMHQADAIYPV
RNH2_METMA --Q-----LKPDIVYADAA-DVKAERFAENLLRQYAKTSPDHAKKIKVVSMHQADAIYPV
RNH2_THEKO L-K-----VKPDVIYADAA-DVDEERFARELGERLN-------FEAEVVAKHKADDIFPV
RNH2_PYRFU L-Q-----IKPALIYADAA-DVDANRFASLIERRLN-------YKAKIIAEHKADAKYPV
RNH2_PYRAB L-K-----VKPEVIYIDSA-DVKAERFAENIRSRLA-------YEAKVVAEHKADAKYEI
RNH2_PYRHO L-R-----IKPQKIYVDSA-DVDPKRFASLIKAGLK-------YEATVIAEHKADAKYEI
RNH2_METTH --E-----AQPDRVIIDSV-DVKPERLEEEIRSHFG--------EIEVTAEHGADTRYYP
RNH2_ARCFU --R-----LKPEIAYVDSP-DVIPERLSRELEEITG---------LRVVAEHKADEKYPL
* .:
RNH2_AERPE VSAASIVAKVVRDARLQVLRR---MYG-VRGSGYPSDPETREWVREVFAR--GEAP-RVI
RNH2_NATPD VGAASIIAKSARERHVEQLSE---QYG-AVGSGYPSDPTTKAFLREAFEQE-GGFP-PCV
RNH2_HALMA VGAASIIAKVARDTHVAELAA---EYG-DVGSGYPSDPTTRTFLADYVDRH-GELP-ACA
RNH2_HALSA VAAASIVAKVARDAHVDALAA---AFDADIGSGYPSDSTTREFLAAYVREH-GELP-ECA
RNH2_METKA VSAASIVAKTYRDWIVRLLEL---EYG-EVGSGYPSDPRTVDRLRRELRRG-GELL-KYF
RNH2_PICTO VSAASIIAKVLRDNEIEKLKS---IYG-DFGSGYPSDPKTLRFLEHSIINH-DNID-NIV
RNH2_THEAC VSAASIVSKVIRDAEIDRLHD---RFG-DFGSGYPSDPRTIDFLKKYLKEN-QDPS-EIV
RNH2_THEVO VSAASIVSKVIRDREIDKIAE---KYG-FFGSGYPSDPRTIDFLRKAMQQG-LDLR-SVA
RNH2_METST VSAASIIAKVERDKQLEIIRQ---EYG-SVGSGYPSDKNTINYLKTIKN---NQFP-PII
RNH2_METMP VSAASIIAKVTRDRVIEEYKE---TFG-EIGSGYPSDPKTKKFLKNYVYEN-RTLP-KIA
RNH2_METJA VSAASIIAKAERDEIIDYYKK---IYG-DIGSGYPSDPKTIKFLEDYFKKH-KKLP-DIA
RNH2_SULAC VSAASIIAKVVRDNIINELKK---TYG-DFGSGYPGDKKTVEWIKDLYSRQ-PTYALPII
RNH2_SACS2 ASAASIIAKVIRDNYIDELKQ---VYG-DFGSGYPADPRTIKWLKSFYEKN-PNPP-PII
RNH2_SULTO ASAASIIAKVIRDNIIDTLKS---KYG-DFGSGYPSDPKTVNWVKNVYKEY-LTPP-PII
RNH2_PYRAE VAAASIVAKVVRDRLIQLLKK---EVG-DFGSGYPSDPRTLQRLRE------GRMPSECI
RNH2_NANEQ VAAASIVAKVIRDREIEKIKE---QTGIDFGSGYPSDKRTRKALEQYYRI----LK-PYI
RNH2_METHJ VSAASIIAKVERDRIIEELSK---EYG-DIGSGYPSDPVTITYLTKYIRHH-NQPP-VIA
RNH2_METBF VSAASIIAKVRRDELIEELKK---EWGLDFGSGYPSDPKTKEFLLNWGKEHSGEFP-EIV
RNH2_METAC VSAASIIAKVRRDELIEEIKK---EWSVDFGSGYPSDPKTKAFLLKWGKEHDGKFP-EIV
RNH2_METMA VSAASIIAKVRRDELIEELKR---EWCIDFGSGYPSDPKTRGFLLKWGKEHGGDFP-DIV
RNH2_THEKO VSAASILAKVTRDRAVEKLKE---EYG-EIGSGYPSDPRTRAFLENYYREH-GEFP-PIV
RNH2_PYRFU VSAASILAKVVRDEEIEKLKK---QYG-DFGSGYPSDPKTKKWLEEYYKKH-NSFP-PIV
RNH2_PYRAB VSAASILAKVIRDREIEKLKA---EYG-DFGSGYPSDPRTKKWLEEWYSKH-GNFP-PIV
RNH2_PYRHO VSAASIIAKVTRDREIEKLKQ---KYG-EFGSGYPSDPRTKEWLEEYYKQY-GDFP-PIV
RNH2_METTH VAAASIIAKVERDLEIESIQKKNRKLG-DIGSGYPSDPRTREFLESFTY---DELP-DFV
RNH2_ARCFU VAAASIIAKVEREREIERLKE---KFG-DFGSGYASDPRTREVLKEWIAS--GRIP-SCV
..****::* *: : ****..* * :
RNH2_AERPE RYTWSTVRKLGG--PWRSKKAGRNRSLDEFLGG---
RNH2_NATPD RTSWSTCERIRA--------EAEQTDLDGF------
RNH2_HALMA RRSWSTCDDVLA--------AASQSTLSDF------
RNH2_HALSA RASWQTSRDALG--------AAEQSALDEF------
RNH2_METKA RRSWETYKRVES--------EVKQRKLEDFF-----
RNH2_PICTO RKEWKTYKNLVQ---GHI------------------
RNH2_THEAC RIHWSTVQRLLH-------SEKNQKKLF--------
RNH2_THEVO RIHWETYKKIKE------DVESGQKKLF--------
RNH2_METST RKTWKTIENITK------STE---------------
RNH2_METMP RKSWATSKNLLK--------EIEESKIFQWVK----
RNH2_METJA RTHWKTCKRILD------KSKQTKLIIE--------
RNH2_SULAC RRSWKILQDIAP------NYYIRKRDGN--------
RNH2_SACS2 RRSWKILRSTAP------LYYISKEGRRLW------
RNH2_SULTO RRSWKILQEIAP------NYYIRK-----W------
RNH2_PYRAE RWQWKTVGGRIG-------LGRNRHESGENPGDSRG
RNH2_NANEQ RKKW--------------PFEINKKLTDFI------
RNH2_METHJ RSSWETVKNLLH--------QKNQSSLLDF------
RNH2_METBF RQSWQTVENIRE--------ELKKTGNKN-------
RNH2_METAC RQSWQTVENIRE--------ELEKAGKK--------
RNH2_METMA RQSWQTVENIRE--------ELKKS-----------
RNH2_THEKO RKGWKTLKKIAEKVESEKKAEERQATLDRYFRKV--
RNH2_PYRFU RRTWETVRKIEE----SIKAKKSQLTLDKFFKKP--
RNH2_PYRAB RRTWDTAKKIEE------KFKRAQLTLDNFLKRFRN
RNH2_PYRHO RRTWETARKIEE------RFRKNQLTLDKFLK----
RNH2_METTH RRSWATVQKKKQ------------------------
RNH2_ARCFU RMRWKTVSNLRQ------------KTLDDF------
* *