CLUSTAL format seed alignment for MF_00055
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
A2DWN3_TRIVA --------------------------------------------------------MLQP
A5K624_PLAVS ------------------------------------------------------MTSYRK
Q7RG18_PLAYO ------------------------------------------------------MPTYRR
Q6CB70_YARLI ------------------------------------------------------MALKRP
V5DRI1_TRYCR ------------------------------------------------------MVYSRR
MHO1_YEAST -------------------------------------------------------MSIRP
Q74ZF7_EREGS -------------------------------------------------------MSIRP
I7ML70_TETTS ----MSQQIQQTLSSKASQEQSQADKEESKQTQVENQQKKTSTQEQNYDQIFCPKLDVRE
B8C1A5_THAPS -----------------------------------------------------MKSYVRR
YAY4_SCHPO -----------------------------------------------------MSQAIRE
MEMO1_CAEEL MSTWRASLGNTILVFCLKVFQNSRALFLRTFGLPFARYLNFILPSEFKMSLNGFGEHTRS
MEMO1_DANRE ---------------------------------------------------MSNRMVCRE
MEMO1_XENLA ---------------------------------------------------MSNRSVCRE
MEMO1_XENTR ---------------------------------------------------MSNRALCRE
MEMO1_BOVIN ---------------------------------------------------MSNRVVCRE
MEMO1_RAT ---------------------------------------------------MSNRVVCRE
MEMO1_HUMAN ---------------------------------------------------MSNRVVCRE
MEMO1_MACFA ---------------------------------------------------MSNRVVCRE
MEMO1_MOUSE ---------------------------------------------------MSNRVVCRE
MEMO1_DICDI --------------------------------------------------------MIRN
Q5KH61_CRYNJ ------------------------------------------------------MSGVRE
I3XTV4_SULBS ------------------------------------------------------MHKYRK
Q30PF9_SULDN --------------------------------------------------------MKRE
E4TY61_SULKY -------------------------------------------------------MSTRT
C4L846_TOLAT ------------------------------------------------------MQVIHQ
I0IKV0_LEPFC ------------------------------------------------------MTIVRS
D2S5D7_GEOOG -------------------------------------------------------MRVRP
D7GHE8_PROFC -------------------------------------------------------MVTRP
C4ZJW4_THASP ----------------------------------------------------MALASIRP
B7J591_ACIF2 ------------------------------------------------------------
G8QLV8_AZOOP ------------------------------------------------------MPSLRP
F9ZLF3_ACICS ------------------------------------------------------MSHIRP
I3YH75_THIV6 ------------------------------------------------------MSLVRQ
Q727F8_DESVH -------------------------------------------------------MPDRH
E3H5Y6_ILYPC -------------------------------------------------------MTVRK
Q74NK0_NANEQ -----------------------------------------------------------M
Y237_THEAC --------------------------------------------------------MKRK
Y1383_THEVO --------------------------------------------------------MIRK
A0RY15_CENSY -------------------------------------------------------MRTRT
Y215_NITMS --------------------------------------------------------MIRK
Q2FTN8_METHJ -------------------------------------------------------MKSRA
E1RIU4_METP4 -------------------------------------------------------MDVRR
Y890_AQUAE -------------------------------------------------------MRVRE
B5YIM6_THEYD -------------------------------------------------------MIKRR
Q74C45_GEOSL --------------------------------------------------------MVRQ
Q1IL90_KORVE -----------------------------------------------------MSVTIRE
Y1771_AERPE -------------------------------------------------------MKIRN
A2BMN4_HYPBU ----------------------------------------------------MAQLEVRE
Y1438_METS3 --------------------------------------------------------MLRK
Y539_PYRAB --------------------------------------------------------MIRY
Y1626_PYRHO --------------------------------------------------------MRRY
Y1638_PYRFU --------------------------------------------------------MIRR
Y132_THEON --------------------------------------------------------MVRY
Y1477_THEKO --------------------------------------------------------MVRY
Y1726_THEGJ --------------------------------------------------------MIRY
Y605_THENN --------------------------------------------------------MIRE
Y837_THEP1 --------------------------------------------------------MKRK
Y087_THEMA --------------------------------------------------------MKRK
Y860_THESQ --------------------------------------------------------MKRK
Y2310_ARCFU ---------------------------------------------------------MRH
Y2394_METBU ---------------------------------------------------------MRQ
Y1422_METBF ---------------------------------------------------------MRQ
Y601_METAC -------------------------------------------------------MEMRQ
Y1761_METMA -------------------------------------------------------MEMRQ
Y403_METJA ------------------------------------------------------MNKIRY
Y697_METVS --------------------------------------------------------MIRD
Y1387_METMP --------------------------------------------------------MTRN
Y1286_METM6 --------------------------------------------------------MKRN
Y191_METM5 --------------------------------------------------------MKRN
Y632_METM7 --------------------------------------------------------MKRN
Y045_METTH --------------------------------------------------------MIRR
Y963_METKA --------------------------------------------------------MERS
Y1590_CALMQ -------------------------------------------------------MVTRK
Y028_PYRCJ -------------------------------------------------------MRIRK
Y062_PYRAR -------------------------------------------------------MRVRK
Y818_PYRAE -------------------------------------------------------MRVRK
Y1105_PYRIL -------------------------------------------------------MRVRK
Y1357_DESA1 -------------------------------------------------------MKKRS
Y992_IGNH4 -------------------------------------------------------MLVRP
Y2139_METS5 --------------------------------------------------------MKRR
Y066_SACS2 --------------------------------------------------------MRRL
Y2180_SULIY --------------------------------------------------------MKRL
Y2219_SULIL --------------------------------------------------------MKRL
Y2054_SULIM --------------------------------------------------------MKRL
Y2134_SULIA --------------------------------------------------------MKRL
Y2061_SULIK --------------------------------------------------------MKRL
Y739_SULIN --------------------------------------------------------MKRL
Y2062_SULTO --------------------------------------------------------MIRL
Y089_SULAC --------------------------------------------------------MIRI
A2DWN3_TRIVA LAFADAW--YPTG-KSLENLFTTLFSNVKD------------------------------
A5K624_PLAVS AYHAGSW--YSSSGRALKNSIDTHFESISC------------------------------
Q7RG18_PLAYO AYHSGSW--YSDNSNVLKNSIESLFEKINL------------------------------
Q6CB70_YARLI ATHAGSW--YSSNATKLGAEVDRHLAN---------------------------------
V5DRI1_TRYCR ASHANSW--YEGSAKVLKATVDDLFERV--------------------------------
MHO1_YEAST ATHAGSW--YSNRAQELSQQLHTYLIKSTL------------------------------
Q74ZF7_EREGS ATHAGSW--YLSNPTRLSQQLSKFLNDATT------------------------------
I7ML70_TETTS PTYQGLW--YSSQDYELNIQLNVWLDMAKC------------------------------
B8C1A5_THAPS AHHAGSW--YSEEPNELDEALANYLAKA--------------------------------
YAY4_SCHPO ATHAGSW--YLDDTELLTKQLKSFIKNPT-------------------------------
MEMO1_CAEEL ASHAGSW--YNANQRDLDRQLTKWLDNA--------------------------------
MEMO1_DANRE ASHAGSW--YTASGSQLNAQLEGWLSQAQS------------------------------
MEMO1_XENLA ASHAGSW--YSASGSQLSAQLDGWLSQAQT------------------------------
MEMO1_XENTR ASHAGSW--YTASGSQLSAQLDGWLSQAQT------------------------------
MEMO1_BOVIN ASHAGSW--YTASGPQLNAQLEGWLSQVQS------------------------------
MEMO1_RAT ASHAGSW--YTASGPQLNAQLEGWLSQVQS------------------------------
MEMO1_HUMAN ASHAGSW--YTASGPQLNAQLEGWLSQVQS------------------------------
MEMO1_MACFA ASHAGSW--YTASGPQLNAQLEGWLSQVQS------------------------------
MEMO1_MOUSE ASHAGSW--YTASGPQLNAQLEGWLSQVQS------------------------------
MEMO1_DICDI CTHAGSW--YLDNARKLEKQLSDWLSEASR------------------------------
Q5KH61_CRYNJ ATHAGSW--YTSSRPGLHKQLSQNLSAV--------------------------------
I3XTV4_SULBS ASVAGMF--YPDNCSELKHYISHFDKATPT------------------------------
Q30PF9_SULDN MSVVGSF--YPARAVELERYFEHFSTTY--------------------------------
E4TY61_SULKY MSVAGSF--YPASAAEINDMIFHFNSVIEA------------------------------
C4L846_TOLAT PAVADMF--YPADPDRLRDWMQHHVKAA--------------------------------
I0IKV0_LEPFC PAVAGVF--YPKEPDILLDMVEGMLEEA--------------------------------
D2S5D7_GEOOG PAVAGRF--YPADPEELHDLVDRLLDEVCG------------------------------
D7GHE8_PROFC TAVAGSF--YPGQRGRLTRELDTLFEQADR------------------------------
C4ZJW4_THASP AAVAGQF--YPRDERVLRTQLAEMLSTAVAFE----------------------------
B7J591_ACIF2 -----MF--YPGEAAVLRTEVERLLARA--------------------------------
G8QLV8_AZOOP AAVAGLF--YPADPAQLGADIDAYLAQA--------------------------------
F9ZLF3_ACICS PAVAGRF--YPARVTELQHQLDAFIPSS--------------------------------
I3YH75_THIV6 PAVADRF--YPGDPRELTRMLDGFLANA--------------------------------
Q727F8_DESVH PIVSGVF--YPGTSRSLRHAVDALLRTPPLPVPEPVLQAMADATRQEAHPAVCDGPDVSS
E3H5Y6_ILYPC CGVAGSF--YPNSPEEIKEIFEEALQKESD------------------------------
Q74NK0_NANEQ GFAAGKF--YPSNREQLIALLNELFKGLK-------------------------------
Y237_THEAC PAVAGYF--YPERKDELYSLLSSFAIPEQH------------------------------
Y1383_THEVO PAVAGYF--YPSNRNELLSLISSFHVQQSE------------------------------
A0RY15_CENSY PAAAGKF--YPAGADETRDTIRWCVNHP-S------------------------------
Y215_NITMS PVVAGQF--YPGTKNELEEMINSCIQHK-F------------------------------
Q2FTN8_METHJ STVAGMF--YPGEPGRLRQLLSELFRNVT-------------------------------
E1RIU4_METP4 VTLAGRF--YPGEPASLKEQLAYFFSHVAL------------------------------
Y890_AQUAE PAVAGTF--YPKDKEELNKLMDLLCG---F------------------------------
B5YIM6_THEYD PSVAGYF--YPSNSKELLQEIEEYMPTT--------------------------------
Q74C45_GEOSL PAVAGQF--YTDDPRRLREELGHLIR----------------------------------
Q1IL90_KORVE PAVAGRF--YPGNPEKLTADIGDYTTPTNA------------------------------
Y1771_AERPE PAHAGTF--YPATREELVKSIESSFTHP-L------------------------------
A2BMN4_HYPBU PQ-AGIWGFYPLNRGELLRTIEACLLDKRF------------------------------
Y1438_METS3 PAVAGMF--YPDDSEELVKTIEDCFLHS-F------------------------------
Y539_PYRAB PAVAGQF--YP-EGETLVEMLEEFFRDL--------------------------------
Y1626_PYRHO PAVAGQF--YP-EGDALIEMLSSFFKDL--------------------------------
Y1638_PYRFU AVVAGQF--YPDDA-ELVEMLKRFFTDL--------------------------------
Y132_THEON PAVAGSF--YPGD-ETLIEMLEKFFRDL--------------------------------
Y1477_THEKO PAVAGSF--YPAD-EELVLMLERFFSDL--------------------------------
Y1726_THEGJ PAVAGSF--YPAD-DELILMLEKFFSDL--------------------------------
Y605_THENN PVVAGLF--YPSRKDELIEQIRICFLDRRI------------------------------
Y837_THEP1 PAVAGLF--YPSRRDELVEQIRICFLDKRI------------------------------
Y087_THEMA PAVAGLF--YPSRRDELIEQIRMCFLDKRI------------------------------
Y860_THESQ PAVAGLF--YPSRRDELIEQIRMCFLDKRI------------------------------
Y2310_ARCFU PRVAGSF--YPANPESLLAMLREYTYPA--------------------------------
Y2394_METBU PTVAGKF--YPLSTKALRKEIVKCFHGLEI------------------------------
Y1422_METBF PAVAGQF--YPLRPDNLEKELKQCFEGLEI------------------------------
Y601_METAC PAVAGQF--YPLHCENLEKELTRCFEGLEI------------------------------
Y1761_METMA PAVAGQF--YPLRCENLENELKRCFEGLEI------------------------------
Y403_METJA PAVAGLF--YPSHPDELIDMIEQCYLHK-F------------------------------
Y697_METVS TVVSGIF--YPLEYHDLIEMIEYCYLNP-R------------------------------
Y1387_METMP PVVAGMF--YPAEYHELLEMIEYCYLNP-R------------------------------
Y1286_METM6 PVVAGMF--YPAEYHELLEMIEYCYLSP-R------------------------------
Y191_METM5 PVVAGMF--YPAEYHELLEMIEYCYLSP-R------------------------------
Y632_METM7 PVVAGMF--YPADYHELLEMIEYCYLSP-R------------------------------
Y045_METTH PAVAGAF--YERDPAALRRRIEWCFEHE-L------------------------------
Y963_METKA PAVAGQF--YPADPEELRKMIEWCFRHE-L------------------------------
Y1590_CALMQ PAVAGMF--YEASKDGLINQIKWSIEHE-L------------------------------
Y028_PYRCJ PAVAGYF--YESRADELQARIEWSIKHE-I------------------------------
Y062_PYRAR PAVAGYF--YPAEKEKLIQQIDWSIKHE-L------------------------------
Y818_PYRAE PAVAGYF--YESGREELLQQIEWAVKHE-L------------------------------
Y1105_PYRIL PAVAGYF--YESDREKLLQQLEWAIKHE-L------------------------------
Y1357_DESA1 PIVAGYF--YPDKPGELRSVIEWSFKHG-I------------------------------
Y992_IGNH4 PAVAGTF--YPADAEELIRLIEWSFTHP-L------------------------------
Y2139_METS5 PAVAGSF--YEDDSAQLRKRIEWAFHHP-I------------------------------
Y066_SACS2 PAVAGSF--YESDPKKLKMQIEWSFRHN-I------------------------------
Y2180_SULIY PAVAGSF--YESDPKKLKMQIEWSFRHN-I------------------------------
Y2219_SULIL PAVAGSF--YESDPKKLKMQIEWSFRHN-I------------------------------
Y2054_SULIM PAVAGSF--YESDPKKLKMQIEWSFRHN-I------------------------------
Y2134_SULIA PAVAGSF--YESDPKKLKMQIEWSFRHN-I------------------------------
Y2061_SULIK PAVAGSF--YESDPKKLKMQIEWSFRHN-I------------------------------
Y739_SULIN PAVAGSF--YESDPKKLKMQIEWSFRHN-I------------------------------
Y2062_SULTO PAVAGAF--YEGEEDKLKKQIEWSFLHP-L------------------------------
Y089_SULAC PAVAGSF--YEADPVRLRKQIEWSFLHD-L------------------------------
: * .
A2DWN3_TRIVA ----------KP-----------IEGKVKAVISPHAGYRHCAETASHAFATI------DP
A5K624_PLAVS -----------------------KKQSVKAAICPHAGYDYALQTNSHVYACI------SV
Q7RG18_PLAYO -----------------------PKQQVKAAICPHAGYAYCLETSSHVYSCI------NV
Q6CB70_YARLI ----------GASVLGKS-----AIPGARVLVGPHAGLAYAGPQLGETYAAF------DF
V5DRI1_TRYCR -----------------KDFQLGGDEKLIGIISPHAGISYSGPTAAHVYKVLRNYIYGPK
MHO1_YEAST ---------------------KGPIHNARIIICPHAGYRYCGPTMAYSYASL------DL
Q74ZF7_EREGS ----------EHGG---------VQRGTRAIISPHAGYSYCGETMAKCYAKL------DV
I7ML70_TETTS --------------------DITSIKSIKAIIAPHAGFSFSGPTAAWAYRYL------KQ
B8C1A5_THAPS -----------------------MVASSKTSISPHAGFQYSGPTAAYSYLAL--KEALIS
YAY4_SCHPO -----------------------PETGKRFVISPHAGYMYSGKVASQGFQQL------DF
MEMO1_CAEEL ----------GP-----------RIGTARALISPHAGYSYCGETAAYAFKQV------VS
MEMO1_DANRE -----------------------IAGPARAIIAPHAGYTYCGACAAHAYKQV------DP
MEMO1_XENLA -----------------------SKRPARAIIAPHAGYTYCGSCAAHAYKQV------DP
MEMO1_XENTR -----------------------SKRPARAIIAPHAGYTYCGSCAAHAYKQV------DP
MEMO1_BOVIN -----------------------TKRPARAIIAPHAGYTYCGSCAAHAYKQV------DP
MEMO1_RAT -----------------------TKRPARAIIAPHAGYTYCGSCAAHAYKQV------DP
MEMO1_HUMAN -----------------------TKRPARAIIAPHAGYTYCGSCAAHAYKQV------DP
MEMO1_MACFA -----------------------TKRPARAIIAPHAGYTYCGSCAAHAYKQV------DP
MEMO1_MOUSE -----------------------TKRPARAIIAPHAGYTYCGSCAAHAYKQV------DP
MEMO1_DICDI -----------------------QNQNVKSIIAPHAGYSYSGRAAAYAYINL------IP
Q5KH61_CRYNJ ----------KPISTLDYDPPV---SNAKAIIAPHAGYSYSGPAAAWAYAAV------PT
I3XTV4_SULBS ---------------FT------QDLFPRALIVPHAGYIYSGYTANLAYAYT------AS
Q30PF9_SULDN ----------DEENIL-------PDIKSRVVIVPHAGYIYSGYSANVAYRVL------KK
E4TY61_SULKY ----------HSDIIKSF-----STLYGNAIIVPHAGWVYSGFTANVAYRIL------NN
C4L846_TOLAT ---------------PE------TGRKPRMLILPHAGYRFSGAIAAQGYSLL-------Q
I0IKV0_LEPFC -----------LGKIPPAIQ---ARGTPRALIVPHAGLIYSGPIAASAYCLM------NP
D2S5D7_GEOOG ----------QP-----------RPVPPAAVVAPHAGYRYSGAVAATAYAHL------TA
D7GHE8_PROFC ----------PPAQV--------SPARVKAIVVPHAGYVYSGTTAATGYELL------RG
C4ZJW4_THASP -----------------------SAPAPKAIIVPHAGYMYSGPVAASAYALL------AP
B7J591_ACIF2 ----------------EQDGEAASAPWPKAIIVPHAGYIYSGAVAASGYALL-----AKG
G8QLV8_AZOOP ----------RPPA---------AAGPIKALIVPHAGYLYSAPIAATAYAAL-----APQ
F9ZLF3_ACICS ----------VAS----------KQLHPKVLIAPHAGYVYSGPVAGKAYAQL-----QGL
I3YH75_THIV6 ----------QP-----------RTPPPKAVIVPHAGYIYSGPIAASAYATL------AP
Q727F8_DESVH DATSGLTPGVAQGAAPKPPAPASVTTDALLVMLPHAGYVYSGRVAGRTLSQV------RL
E3H5Y6_ILYPC ----------NIKTEL-------KNKNIIGGVSPHAGYVYCVREAVHLFEIL------RE
Q74NK0_NANEQ -----------------------KEYSLKAGIVPHAGYIYSGKAMAEFWINS------DR
Y237_THEAC -----------------------VSGTIIGAVVPHAGIIYSGRTAMYSYRAI------EK
Y1383_THEVO -----------------------VSCQPIGVVVPHAGIVYSGRTAMYSYNAL------RN
A0RY15_CENSY ----------GPGPDPP------ELDGVIGMICPHAGYRYSGPVACHGLLSI------RH
Y215_NITMS ----------GPGNQIQ------NNEGIYGVISPHAGYVYSGPTACYSYKAI------SS
Q2FTN8_METHJ -----------------------SSGDAAGVVSPHAGYVYSGKTAAKAFAAF------DE
E1RIU4_METP4 ---------------PHP-------VDACGIVSPHAGTIYSGQAAAYSFSAI------PS
Y890_AQUAE ----------EPK----------EKIKPKAILVPHAGYIYSGKTACEVYKRI------EI
B5YIM6_THEYD -----------------------LKIDAFGAICPHAGYVYSGSVAGAVYSKL------KP
Q74C45_GEOSL ---------------PVP-----APRRVTGVIAPHAGYMYSGAIAGAVYGSI------VI
Q1IL90_KORVE -----------------------EKLAAIGCVVPHAGYMYSGHVAGAVYERL------DL
Y1771_AERPE ----------GPGRLPQRGGG--SGEQAIAYIPPHAGYMYSGPIAAHVYYDM------SL
A2BMN4_HYPBU ----------GPGRLPDRNAR--PRYTPVGGVVPHAGYSYSGPCAAHLYLEL------AE
Y1438_METS3 ----------GPGKIPDIESFE-GNDYPVNVMVPHAGFQYSGTIAAHSYCEL------AK
Y539_PYRAB ----------GEQG---------NSRKITAGVAPHAGYVFSGYTASRTYKAI------YE
Y1626_PYRHO ----------GEEG---------TKRTITAGVAPHAGYVFSGFTASRTYKAI------YE
Y1638_PYRFU ----------GEEG---------NSRRITAGVAPHAGYIFSGYTASRTYKAI------YE
Y132_THEON ----------GEHG---------SERKITAGVVPHAGYVFSGYTASRTFKAI------YE
Y1477_THEKO ----------GEEG---------NDRRITAGVAPHAGYIFSGYTASRTYKAI------FE
Y1726_THEGJ ----------GEEG---------SERRITAGVAPHAGYIFSGYTASRTYKAI------FE
Y605_THENN ----------GPGELPGPVEK--NLQNPVGLVSPHAGYIYSGPVAAWGFLEV------AR
Y837_THEP1 ----------GPGELPDPSET--KLQSPIGFVSPHAGYIYSGPVAAWGFLEV------AK
Y087_THEMA ----------GPGKLPGPVET--KLQNPIGLVSPHAGYIYSGPVAAWGFLEA------VK
Y860_THESQ ----------GPGELPVPVET--KLQNPIGLVSPHAGYIYSGPVAAWGFLEA------VK
Y2310_ARCFU -----------------------KDESVIACVSPHAGYVYSGRTAGKVHSLL------PD
Y2394_METBU -----------------------MSEDVIGAVVPHAGYVYSGPVAAHAFARL------PK
Y1422_METBF -----------------------RERNILGAVCPHAGYVYSGRVAAHVYAVL------PK
Y601_METAC -----------------------REREVFGAVCPHAGYIYSGKVAAHVYATL------PE
Y1761_METMA -----------------------REQEVLGAVCPHAGYMYSGKVAAHVYATL------PE
Y403_METJA ----------GPKSMPVHG----TYEKPIGLLCPHAGYVYSGPIQAHSYYEL------SK
Y697_METVS ----------GPKKLPSKLG---RYEKPIGVISPHAGYVYSGPIAAHSYKEI------SK
Y1387_METMP ----------GPRELPSKRG---KYTKPLGIVSPHAGYIYSGPVAAHGYKKI------SE
Y1286_METM6 ----------GPKELPSKRG---NYTKPLGIVSPHAGYIYSGPVAAHGYKKI------SE
Y191_METM5 ----------GPKELPSKRG---NYTKPLGIVSPHAGYIYSGPVAAHGYKKI------SE
Y632_METM7 ----------GPKELPSKRG---NYTKPLGIVSPHAGYIYSGPVAAHGYKKI------SE
Y045_METTH ----------GPGTLPAVG----SMRRIKGVIAPHAGYMYSGPVAAHAYHEL------VS
Y963_METKA ----------GPGDLPETND---GPCTLPGVVAPHAGYQFSGPVAAHTYKVL------AE
Y1590_CALMQ ----------GPKSTMNVKE---NRQYVLSVIVPHAGYVYSGPVAAHAYVEV------GK
Y028_PYRCJ ----------GPKA-PVLPK---LGTEALGGVVPHAGYMYSGPVAAWLYSAL------AG
Y062_PYRAR ----------GPKALQMPK----LGEKALGGVVPHAGYIYSGPVAAWLYSAL------AG
Y818_PYRAE ----------GPKALQMPK----LGGEALGGVAPHAGYMYSGPVAAWLYSAL------AG
Y1105_PYRIL ----------GPKAPQIPK----LGAETLGGVAPHAGYIYSGPVAAWVYSAL------AG
Y1357_DESA1 ----------GPGKPPSPSDI--PATNSIGYVAPHAGYIYSGPVAAHVYFDM------AL
Y992_IGNH4 ----------GPGEVPEVSPV--RRKASVGYMVPHAGYIYSGPVAAWSYYHL------AQ
Y2139_METS5 ----------GPGGIPSVGST--GSRSNPIFIVPHAGYIYSGPVAAHSYYYL------AQ
Y066_SACS2 ----------GPRDIPKQSYEK-KKRDNLFFIVPHAGYIYSGPVAAHSYYYL------AS
Y2180_SULIY ----------GPRDIPKQTYEK-KKRDNLFFVVPHAGYIYSGPVAAHSYYYL------VS
Y2219_SULIL ----------GPRDIPKQTYEK-KKRDNLFFVVPHAGYIYSGPVAAHSYYYL------VS
Y2054_SULIM ----------GPRDIPKQTYEK-KKRDNLFFVVPHAGYIYSGPVAAHSYYYL------VS
Y2134_SULIA ----------GPRDIPKQTYEK-KKRDNLFFVVPHAGYIYSGPVAAHSYYYL------VS
Y2061_SULIK ----------GPRDIPKQTYEK-KKRDNLFFVVPHAGYIYSGPVAAHSYYYL------VS
Y739_SULIN ----------GPRDIPKQTYEK-KKRDNLFFVVPHAGYIYSGPVAAHSYYYL------VS
Y2062_SULTO ----------GPGKIPQVPPQK-SKRNNLFFIVPHAGYMYSGPVAAHAYYYL------AS
Y089_SULAC ----------GPKSLPSVPQNKPPQRSNRFFVVPHAGYMYSGPVAAHAYYHL------SL
: **** ..
A2DWN3_TRIVA SL----YSRVIIMGPSHRLPIDYCTISEA-KSFETPTRSLEIDP----------------
A5K624_PLAVS EN----VKNIFILGPNHHIYNKGCLFPHV-EKYETPFGFLQINRE---------------
Q7RG18_PLAYO EN----IKNIFILGPNHHIYNKGCLLPQV-DKYETPFGFLQINKDGNLPLATCHLPLATY
Q6CB70_YARLI KN----IKRLFILGPSHHVYLEHAATSAF-HSYETPFGNVNVDVE---------------
V5DRI1_TRYCR GSN---VTHIFLLGPDHHKGFDGVEMSGA-QQYETPFGALSIDTS---------------
MHO1_YEAST NRN---VKRIFILGPSHHIYFKNQILVSAFSELETPLGNLKVDTD---------------
Q74ZF7_EREGS NKD---TKRVFVLGPSHHFHFRNIALVSRYTALETPLGNLQVDEE---------------
I7ML70_TETTS NPPTQ-KLRVFVLGPFHYIFIRSCALSGM-KTYETPLGNIEIDQE---------------
B8C1A5_THAPS NPS---LRTVVVLHPSHHIYLDGCAVSGA-STLETPLGDLVVDNN---------------
YAY4_SCHPO SK----IQRVFVFGPSHHIFTRKCLVSRA-SICSTPLGDLKVDED---------------
MEMO1_CAEEL SA----VERVFILGPSHVVALNGCAITTC-SKYRTPLGDLIVDHK---------------
MEMO1_DANRE SI----TRRVFILGPSHHVPLSRCALSPA-EVYRTPLYDLRIDQK---------------
MEMO1_XENLA SV----TRRVFILGPSHHVALSRCALSTV-DIYRTPLYDLHVDQK---------------
MEMO1_XENTR SV----TRRVFILGPSHHVALSRCALSTV-DIYRTPLYDLHIDQK---------------
MEMO1_BOVIN SI----TRRIFILGPSHHVPLSRCALSSV-DIYRTPLYDLRIDQK---------------
MEMO1_RAT SI----TRRIFILGPSHHVPLSRCALSSV-DIYRTPLYDLRIDQK---------------
MEMO1_HUMAN SI----TRRIFILGPSHHVPLSRCALSSV-DIYRTPLYDLRIDQK---------------
MEMO1_MACFA SI----TRRIFILGPSHHVPLSRCALSSV-DIYRTPLYDLRIDQK---------------
MEMO1_MOUSE SV----TRRIFILGPSHHVPLSRCALSSV-DIYRTPLYDLRIDQK---------------
MEMO1_DICDI EN----YKRVFILGPSHHVYMKTCGLTKL-DTWETPIGNLKVDKD---------------
Q5KH61_CRYNJ EK----IKRVFLLGPSHHAYLPGVALSKF-EAYETPLGDIPLDTD---------------
I3XTV4_SULBS RRCD--IERVVVIGPSHRVYIAGASIAFF-DAYHTPCGDITIDLS---------------
Q30PF9_SULDN SG----VKKFLVIGPSHRVGFEGISLGDF-SSYETPFGAIPASLD---------------
E4TY61_SULKY SE----PKTVVVIGPSHRVGFDGVSICDL-THYQTPLGDLTIDPQ---------------
C4L846_TOLAT KGD---FKRVIVLCPAHRVYLQGIAVPEHWDGEATPFGTIPLDKP---------------
I0IKV0_LEPFC SFL---PKRIFVLGPSHRIFFKGIATSTA-TSFGTPLGEIPVDRT---------------
D2S5D7_GEOOG APHA--VTRVVLLGPAHFWPLDGMAVPAV-DALATPLGSVDVDDD---------------
D7GHE8_PROFC RP----INRVVVLGPTHRVGIRGMALAGA-DAFDTPLGSVPVDPD---------------
C4ZJW4_THASP LRER--IRRVVMLGPTHRVAVRGFSLPAA-QRFATPLGEVPVARG---------------
B7J591_ACIF2 RGH---IRRVVLLGPAHRLPFRGLALPGV-QAMQTPLGTVAVDQA---------------
G8QLV8_AZOOP AGR---IRRVILLGPTHRVAVRGLAVPTV-DSFATPLGPLPIDAE---------------
F9ZLF3_ACICS RGQ---ISRVVLLGPAHYVRLRGLAIPEA-DAFATPLGTVPVNRD---------------
I3YH75_THIV6 ARES--VTRVILMGPSHRVPFRGLATSSA-DWFDTPLGAVPLDRV---------------
Q727F8_DESVH ------APVVFMLGPNHTGRGAPLAVWPE-GDWLTPLGSVPVHER---------------
E3H5Y6_ILYPC KGEK--YDTVVLVNPNHTGYGEAVSIDSN-KAWETPFGSIELDSE---------------
Q74NK0_NANEQ ------NKTYAIIGTNHTGLGSLANVSLM--PIETPLGIAKIDEE---------------
Y237_THEAC SA----VRDFVIIGPNHRPLTPYASLYPE-GEWSTPLGDALINDR---------------
Y1383_THEVO SS----IRDFIIIGPNHRPMTPYASIFPS-GSWETPLGNAIINEE---------------
A0RY15_CENSY TS----PRLFVMAGPNHWGLGLGIAGIGA-CRWITPAGYVETDDA---------------
Y215_NITMS KN----PELVIILGPNHFGVGKDVATMVN-AQWETPLGLVDVDSE---------------
Q2FTN8_METHJ KF----DGTFLVIGPSHRGFPTCISQVP----WETPLGMLEPDIE---------------
E1RIU4_METP4 DF----NGTFIVVAPSHAGYPDCTSG----LSWETPLGIIECDEA---------------
Y890_AQUAE ------PEKVVLLGPNHTGLGKPISVYSG-DAWETPYGVVEIDGE---------------
B5YIM6_THEYD ------KEIFILIGPNHTGYGENVALMTE-GEWEIPLGSIKIHSE---------------
Q74C45_GEOSL ------PRTVVILGPNHHGLGAAASLYPD-GTWLSPLGEVPIEQR---------------
Q1IL90_KORVE ------PKRFVILCPNHTGAGHPLAVMRE-GSWRTPLGDAAIDAE---------------
Y1771_AERPE GRK---PDVVVLLGPNHTGLGLAASLWDE-GVWRTPLGEVEVDSE---------------
A2BMN4_HYPBU NAPE--VDTVVVMGTNHTGYGGVYTTTTRYKAWATPLGTVETDIE---------------
Y1438_METS3 NGF---PEVFIIIGPNHTGLGSEVSVFNK-GEWITPLGNIQVDEE---------------
Y539_PYRAB DGL---PETFVIFGPNHTGLGSPIAVYPE-GDWVTPLGKVKIDSE---------------
Y1626_PYRHO DGL---PEVFVIFGPNHTGLGSPIALYPE-GEWITPMGSIKVDSK---------------
Y1638_PYRFU DGL---PEVFVILGPNHTGLGSPIAVYPK-GEWETPLGRIKVDEK---------------
Y132_THEON DGL---PETFVILGPNHTGIGSPIAVYPS-GSWLTPLGEIEVDSE---------------
Y1477_THEKO DGL---PETFVILGPNHTGLGSPIAVHPP-GTWITPLGEIEVDGE---------------
Y1726_THEGJ DGL---PETFVILGPNHTGLGSPIAVYPE-GEWLTPLGSIEVDAE---------------
Y605_THENN IGK---PSLVVIIGPNHTGLGKPVGIWPE-GFWETPLGRVPVNEE---------------
Y837_THEP1 FGE---PSVVVIIGPNHTGLGRPVGVWPE-GEWETPLGTVPVNQR---------------
Y087_THEMA FGE---PSVVVIIGPNHTGLGRPVGVWPE-GEWETPLGTVPVNER---------------
Y860_THESQ FGE---PSVVVIIGPNHTGLGRPVGVWPE-GEWETPLGTVPVNQR---------------
Y2310_ARCFU ------AETFVIVGPNHTGYGLPVAVS-T-DTWLTPLGEVEVDTE---------------
Y2394_METBU ------ADTYVIFGPNHTGYGSPVAMS-Q-DVWNTPFGDVETDRE---------------
Y1422_METBF ------ADTYVLFGPNHTGYGSPVSVS-T-DTWKTPLGIIEVDRE---------------
Y601_METAC ------ADTYVLFGPNHTGYGSPVSLS-R-ETWKTPLGTIDVDLE---------------
Y1761_METMA ------ADTYVIFGPNHTGYGSPVSVS-R-ETWKTPLGNIDVDLE---------------
Y403_METJA RVDALEETTVVILGPNHTGLGSGVSVM-D-GIWRTPLGDVKCDEE---------------
Y697_METVS KVSG--NITAVIIGPNHSGMGSVVSTM-E-GIWKTPLGNLEIDNE---------------
Y1387_METMP NISG--EITAIILGPNHTGLGSGIATM-K-GTWKTPFGDMEIDNE---------------
Y1286_METM6 NVSG--EVTAIILGPNHTGLGSGISTM-K-GIWKTPFGDMEIDNE---------------
Y191_METM5 NING--EVTAIILGPNHTGLGSGISTM-K-GIWKTPFGDMEIDNE---------------
Y632_METM7 NVSG--EVTAIILGPNHTGLGSGISTM-K-GIWKTPFGDMEIDNE---------------
Y045_METTH DGI---PGTLVIICPNHTGMGSGVSLMQQ-GAWETPLGTVEIDSE---------------
Y963_METKA SGT---PETVVILGPNHTGLGSAVATMTD-GAWRTPLGSVEIDSE---------------
Y1590_CALMQ YIK---PKVFVIIGPNHYGVGSPAAIMTS-GTWETPLGQVEIDEE---------------
Y028_PYRCJ YGA---PTTFVIIGPNHYGIGAPVAIMKS-GAWETPFGRVEIDEE---------------
Y062_PYRAR YGK---PDAIIIIGPNHYGIGAPVAVMKS-GVWETPLGRVEVDGD---------------
Y818_PYRAE YGK---PDVFVIVGPNHYGIGAPVAIMKS-GAWETPLGRVEVDRE---------------
Y1105_PYRIL FGK---PDVFIIIGPNHYGIGAPVAIMKS-GVWETPLGRVEIDGE---------------
Y1357_DESA1 NKK---PDTIVILGTNHTGLGRPVSVYPE-GVWETPLGDLVVDSE---------------
Y992_IGNH4 EGA---PETVVIIGPNHTGLGPAVSVMPP-SIWETPLGGVKTDDE---------------
Y2139_METS5 EGK---PDIVIILGPNHTGYGSQVSIWPG-GDWETPLGSAQVNAQ---------------
Y066_SACS2 EGK---PDVVIILGPNHTGLGSYVSAWPK-GEWETPLGSVKVDEE---------------
Y2180_SULIY EGR---PDVVIILGPNHTGLGSYVSAWPK-GEWETPLGSVKIDEE---------------
Y2219_SULIL EGR---PDVVIILGPNHTGLGSYVSAWPK-GEWETPLGSVKIDEE---------------
Y2054_SULIM EGR---PDVVIILGPNHTGLGSYVSAWPK-GEWETPLGSVKIDEE---------------
Y2134_SULIA EGR---PDVVIILGPNHTGLGSYVSAWPK-GEWETPLGSVKIDEE---------------
Y2061_SULIK EGR---PDVVIILGPNHTGLGSYVSAWPK-GEWETPLGSVKIDEE---------------
Y739_SULIN EGR---PDVVIILGPNHTGLGSYVSAWPK-GEWETPLGSVKIDEE---------------
Y2062_SULTO EGI---PDTVIILGPNHTGLGSYVSLWPK-GKWKTPLGEIEIDEQ---------------
Y089_SULAC EGS---PDTVIILGPNHTGLGSYVSIWHK-GKWKTPLGEVSVDDE---------------
. : *
A2DWN3_TRIVA -------------IAEELTSK------YGSIFKKLSIETSNREHSLELMLPWIDY---IF
A5K624_PLAVS -------------VISEILQN-----DVDHLFDFIGDEDDEEEHSIEMQLPLIKY---II
Q7RG18_PLAYO HLPLTTINVYIYMFISDIMNN----DTQNLYD-YIDEIDDEEEHSIEMQLPLIKY---II
Q6CB70_YARLI -------------TTQKLNDS-------GVTK-YMSATTDKDEHSFEMHMPFLKR---LV
V5DRI1_TRYCR -------------VVSSVFQS--LKAAGVQTT-RMSQSTDEEEHSIEMQLPFISH---IL
MHO1_YEAST -------------LCKTLIQKEYPENGKKLFK-PMDHDTDMAEHSLEMQLPMLVE---TL
Q74ZF7_EREGS -------------TVSKLLGH-------ARLFRPLDYDDDQKEHSLEMQYPMLHE---TL
I7ML70_TETTS -------------TIQQLLKE-------GSFE-VSDKDAEEEEHSIEMQLCFLIK---TL
B8C1A5_THAPS -------------LREQMLST-------GKFD-VMEKRVDEQEHSGEMQYPFIAK---VI
YAY4_SCHPO -------------LCQKLVAS-------DNSFDSMTLDVDESEHSLEMQFPLLAF---HL
MEMO1_CAEEL -------------INEELRAT-------RHFD-LMDRRDEESEHSIEMQLPFIAK---VM
MEMO1_DANRE -------------VYADLWKT-------GMFE-RMSLQTDEDEHSIEMHLPYTAK---AM
MEMO1_XENLA -------------VYGELWKT-------GMFE-RMSLQTDEDEHSIEMHLPYTAK---AM
MEMO1_XENTR -------------VYGDLWKT-------GMFE-RMSLQTDEDEHSIEMHLPYTAK---TM
MEMO1_BOVIN -------------IYGELWKT-------GMFE-RMSLQTDEDEHSIEMHLPYTAK---AM
MEMO1_RAT -------------IYGELWKT-------GMFE-RMSLQTDEDEHSIEMHLPYTAK---AM
MEMO1_HUMAN -------------IYGELWKT-------GMFE-RMSLQTDEDEHSIEMHLPYTAK---AM
MEMO1_MACFA -------------IYGELWKT-------GMFE-RMSLQTDEDEHSIEMHLPYTAK---AM
MEMO1_MOUSE -------------IYGELWKT-------GMFE-RMSLQTDEDEHSIEMHLPYTAK---AM
MEMO1_DICDI -------------TTNKLFDT-------GSFI-WNTKSVDEDEHSLELQLPYIAK---VA
Q5KH61_CRYNJ -------------TINELRDT-------GIFS-DMKSSTDEDEHSLEMHLPYIRL---IF
I3XTV4_SULBS -------------YAHALQKK-------FAFL-DFHPNAHE-EHSTEVQMPFIHH---YF
Q30PF9_SULDN -------------LVEELSNT---------FL-LSCYRDTHFEHSTEVQFPFIKY---YI
E4TY61_SULKY -------------LTKELRER---------FA-LPYFSEAHHEHSTEVQMPFIKH---YL
C4L846_TOLAT -------------AIASLLSL-------PGVI-AATE-AHRQEHAIEVQLPFLQY---QL
I0IKV0_LEPFC -------------LVDQMETL-------PGID-TYDP-AHTQEHSIEIQLPFLKV---QM
D2S5D7_GEOOG --------------ARTVAAA-------LPGV-AVDDRPHDGEHSLETQLPFLQR---VL
D7GHE8_PROFC --------------LTAIAEA-------VPLV-VTRPDVHAREHSLEVQLPFIRT---VL
C4ZJW4_THASP -------------DWEALQAR-------DDVL--VDDRPHALEHCLEVQLPFLQV---CL
B7J591_ACIF2 -------------GVEALAGL-------PEVR-EMPA-AHAQEHALEVQLPFIQE---VL
G8QLV8_AZOOP -------------ARQRIADL-------PQVV--ADDGAHALEHSLEVQLPFLQR---LL
F9ZLF3_ACICS -------------ALNAISDL-------PQVI-QSDV-PHNPEHSLEVHLPFLQR---ML
I3YH75_THIV6 -------------AINQALAL-------PQVR-SMDE-AHALEHSLEVQLPFLQR---VL
Q727F8_DESVH -------------AAAALLDK-------DGGY-TANRTAHEGEHSLEVLLPLLQV---RH
E3H5Y6_ILYPC -------------FGDELS------------F-PVEPMAQRFEHSGEVMLPYLYY---FI
Q74NK0_NANEQ -------------AAMIFMKN---------GF-DYDDRPFLYEHSVENQIPFLQY---LH
Y237_THEAC -------------MAEALYRD-------SNYI-VKDEESHLMEHSVEVQIPFLQY---LF
Y1383_THEVO -------------LASELYKN-------SQYI-VKDEESHSVEHSIEVQIPFLQY---MF
A0RY15_CENSY -------------GSVELERC---------GI-KEDFFAHSKEHSLEVIVPMLQE---FF
Y215_NITMS -------------AAKEIANN-------SKYI-EIDEFSHSRDHSLEVQIPMLQS---IF
Q2FTN8_METHJ -------------LGSCIHLP----------V-DERAMSYGSENSLEVQMPFIQY---RF
E1RIU4_METP4 -------------LVSALDIN------------RDDFAMAQPENSLEVQMPFIKF---RF
Y890_AQUAE -------------LREKILKY--------PYA-NPDEYAHLYEHSLEVQLPFLQR---YA
B5YIM6_THEYD -------------LAKKIIEK-------SPLA-KDDIHAHLHEHSLEVQLPFI-Y---KL
Q74C45_GEOSL -------------LSSLVLEH-------VPQA-EPDVIAHRFEHSLEVQVPFLRY---LN
Q1IL90_KORVE -------------LADQLLAA-------FPLT-SEDADAHRTEHALEVQLPFLQI---LV
Y1771_AERPE -------------AGRLVVEY-------SGIV-APDDEGHIYEHSLEVQLPFLQY---LY
A2BMN4_HYPBU -------------FIELLKKL-------YPRL-EDDYLAHMREHSIEVELPFLQY---IY
Y1438_METS3 -------------FADTLISF-------SDFA-SADFAAHMREHSIEVQLPFLQY---FS
Y539_PYRAB -------------LAKEIVKL-------SKIA-DLDDLAHKYEHSIEVQLPFIQYIAEKA
Y1626_PYRHO -------------FAKEIVKR-------SGIA-DLDDLAHKYEHSIEVQLPFIQYIAEKA
Y1638_PYRFU -------------LARRITEL-------SEIA-DLDDLAHKYEHSIEVQLPFIQYLAELS
Y132_THEON -------------MAKTIAKL-------SGIA-DLDELAHKYEHSIEVQLPFIQYLAEKA
Y1477_THEKO -------------LAREIAKI-------SGIA-DLDDLAHKYEHSIEVQVPFIQYLAEKA
Y1726_THEGJ -------------MAKEIAKL-------SGIA-DLDELAHKYEHSIEVQVPFIQYLTELA
Y605_THENN -------------AVEILLNS-------SRYA-EEDTLSHLKEHSIEVQLPFLQF---VF
Y837_THEP1 -------------AAEIILNS-------SRYA-EEDFMSHIREHSIEVQIPFLQF---VF
Y087_THEMA -------------AVEIVLSN-------SRYA-EEDFMSHIREHSIEVQIPFLQF---VF
Y860_THESQ -------------AVEVILSN-------SRYA-EEDFMSHIREHSIEVQIPFLQF---VF
Y2310_ARCFU -------------FVEAMPKI---------IT-APDEIAHRYEHSLEVQVPFLQY---LH
Y2394_METBU -------------LGKLLAGT---------II-DMDEVAHRYEHSVEVQIPFLQY---LF
Y1422_METBF -------------LAEGLTGS---------IV-DVDEIGHRYEHSIEVQLPFLQY---RF
Y601_METAC -------------LADGFLGS---------IV-DTDELGHTYEHSIEVQLPFLQY---RF
Y1761_METMA -------------LADGFLGS---------IV-DADELGHKYEHSIEVQLPFLQY---RF
Y403_METJA -------------FVEELWRK-------CEIV-DLDETAHLNEHSIEVQLPFLKHLELLN
Y697_METVS -------------FSERLWKE-------CDII-DLDETAHLKEHSIEVQLPFLKHLELLN
Y1387_METMP -------------FADRLWKE-------CDIL-DMDENSHLREHSIEVQLPFLKHLEDLN
Y1286_METM6 -------------FADKLWKE-------CDVL-DIDENSHLREHSIEVQLPFLKHLEDLN
Y191_METM5 -------------FADRLWKE-------CDVL-DLDENSHLREHSIEVQLPFLKHLEDLN
Y632_METM7 -------------FADKLWKE-------CDVL-DLDENSHLREHSIEVQLPFLKHLEELN
Y045_METTH -------------LAEAIVRE-------SGII-DLDETAHLAEHSCEVHVPFIQY---FT
Y963_METKA -------------FATALVRK-------CGVM-DDDLTAHANEHSIEVQLPFLQY---VY
Y1590_CALMQ -------------VAKQIKAK-------VKDL-AEDPIAFEREHSIEVQVPFIQY---LF
Y028_PYRCJ -------------LASLIASN-------YREI-EDDAHAFSKEHSIEVQLPFIQY---YF
Y062_PYRAR -------------LAELIMRH-------YKGV-EDDFYAFSKEHSVEVQIPFIQY---YF
Y818_PYRAE -------------LAEVITSH-------FKEV-EDDFYAFSKEHSVEVQVPFIQY---YF
Y1105_PYRIL -------------LAEKIMRY-------FKEL-EDDFHAFSREHSIEVQIPFIQY---FF
Y1357_DESA1 -------------IGRLIVEN-------SEIA-EFDEYAHLEEHSIEVQLPFIVY---IY
Y992_IGNH4 -------------AISELLKV-------SNVV-EEDYSAHAYEHSLEVQLPFLQY---LF
Y2139_METS5 -------------LVKELVSV-------SEVV-DIDEKAHLYEHSIEVQLPFLQY---FF
Y066_SACS2 -------------VLMQLVME-------SEVI-DLEEKSHLYEHSIEVQLPFLQY---FF
Y2180_SULIY -------------ILMQLVKE-------SEVI-DLDEKSHLYEHSIEVQLPFLQH---FF
Y2219_SULIL -------------ILMQLVKE-------SEVI-DLDEKSHLYEHSIEVQLPFLQY---FF
Y2054_SULIM -------------ILMQLVKE-------SEVI-DLDEKSHLYEHSIEVQLPFLQY---FF
Y2134_SULIA -------------ILMQLVKE-------SEVI-DLDEKSHLYEHSIEVQLPFLQY---FF
Y2061_SULIK -------------ILMQLVKE-------SEVI-DLDEKSHLYEHSIEVQLPFLQY---FF
Y739_SULIN -------------ILMQLVKE-------SEVI-DLDEKSHLYEHSIEVQLPFLQY---FF
Y2062_SULTO -------------IAMDLVRE-------SEVI-DIDEKAHLYEHSIEVQVPFLQY---FF
Y089_SULAC -------------ISLELVKL-------TEII-DIDERAHLYEHSIEVQIPFLQY---LF
::. *
A2DWN3_TRIVA ----------KGKNVTVVPIMVGHLDQTKLE--QAVSALKPYINDPS----T--LLVISS
A5K624_PLAVS ----------KEKDIKIIPIYVGCIGNDIQKIDRFCNPLKKYFQDEG----N--LFLFSS
Q7RG18_PLAYO ----------KEKDIKIVPIYVGCIGNDVNKINEFSNPLKKYFQDKT----N--AFIFSS
Q6CB70_YARLI ----------GDQNVKIVPIMVGQTSQEYEK--RLAKLLLPYVEDPT----N--AFVIST
V5DRI1_TRYCR -HHPPAGLTGAKNRIQLVPMLVGWTDRETEE--RIGAVLSSYSQDSH----N--IFVLSS
MHO1_YEAST -----KWREISLDTVKVFPMMVSHNSVDVDR--CIGNILSEYIKDPN----N--LFIVSS
Q74ZF7_EREGS -----LQRGVRPSDVKIVPILISYNSTEVDY--AIGKILIEYLQCDD----T--AVIVSS
I7ML70_TETTS ----------GLENIKLIPVMVGSIDSTQEE--KYGKLFSKYINQED----T--LFVIST
B8C1A5_THAPS NDVKKHTPEHDNLSIKVLPIMIGSIKQKKEE--LFGKLLAPFLSDDG----V--FTVISS
YAY4_SCHPO ------LKQGCLGKVKIVPIMIGALTSTTMM--AAAKFLSQYIKDES----N--SFVISS
MEMO1_CAEEL ----------GSKRYTIVPVLVGSLPGSRQQ--TYGNIFAHYMEDPR----N--LFVISS
MEMO1_DANRE --------ENHKDEFSIVPVLVGALSGSKEQ--EYGKLLSKYLADPS----N--LFIISP
MEMO1_XENLA --------ESHKDDLTIVPVLVGALSESKEQ--EFGKVFSKYLADPT----N--LFVISS
MEMO1_XENTR --------ESHKDDLTIVPVLVGALSESKEQ--EFGKLFSKYLADPT----N--LFVISS
MEMO1_BOVIN --------ESHKDEFTIIPVLVGALSESKEQ--EFGKLFSKYLAEPS----N--LFVVSS
MEMO1_RAT --------ESHKDEFTIIPVLVGALSESKEQ--EFGKLFSKYLADPS----N--LFVVSS
MEMO1_HUMAN --------ESHKDEFTIIPVLVGALSESKEQ--EFGKLFSKYLADPS----N--LFVVSS
MEMO1_MACFA --------ESHKDEFTIIPVLVGALSESKEQ--EFGKLFSKYLADPS----N--LFVVSS
MEMO1_MOUSE --------ESHKDEFTIIPVLVGALSESKEQ--EFGKLFSKYLADPS----N--LFVVSS
MEMO1_DICDI --------EKRLLELSIVPIMVGSLSIDLEE--LYGKILAPYFDDPE----N--FFVISS
Q5KH61_CRYNJ ---------QGRDDLKLVPILVGHPSASTSA--KLSEALAKYWQDGE----T--FFVISS
I3XTV4_SULBS ------------KKANVVEIVYGDITYG-----ELSSLINEVLKDDK----T--LIVIST
Q30PF9_SULDN ------------EGASVVELVYSYMKPS-----NLSKIIDFALNHKD----V--GIIIST
E4TY61_SULKY ------------PDVQVVELVYAYAEPF-----MLEPVIEYCLARQN----T--AVVIST
C4L846_TOLAT ------------GDFSLIPLVVGDCPAE-----TVSHAIEQIMTDDT-------LIIVSS
I0IKV0_LEPFC ------------DQVPIIPLIAGESSAS-----SVARVIKTALSFPD----T--LVVIST
D2S5D7_GEOOG -----------GPEVAVLPVLVGRTQPESVA--AVLTAVDGA------------LAVVST
D7GHE8_PROFC ------------PQASVLPVAVGDALPDEVA--ALLDAVWGESDT---------AIVISS
C4ZJW4_THASP ------------ERFEIVPVLVGDASPEATA--SLIERLWGGPET---------LILISS
B7J591_ACIF2 ------------GDVSVVPLVVGDARPDEVA--RVLEKLWGGEET---------VIVISS
G8QLV8_AZOOP ------------GPFTLLPLAVGAASGEAVA--QVLERLWGGEET---------LILVSS
F9ZLF3_ACICS ------------GDFSVVPLLVGDATYTEVA--EVLERLWGGPET---------LIVIST
I3YH75_THIV6 ------------VDFSLAPFVVGDASPESVA--EVLELLWGGPET---------LIVISS
Q727F8_DESVH ------------PALSIIPVAVSEQDAGALQ--RAGASLARTMQELAAAG-VPSSIVLSS
E3H5Y6_ILYPC -----------KKGFKILPICMMRQDLKTAK--NIAEKIKNASEKLN-RK-I--LILISS
Q74NK0_NANEQ -----------GDNFLIVPSVM-FNVYRFAK--EVGKQLALELPER-----V--RLVASS
Y237_THEAC -----------GDGFRFVPVILGDQEIDVAR--DIGEAIMKIEDPF--------IFIASS
Y1383_THEVO -----------GNSFTFVPVILGDQEKVVAN--DIASALMRLSKPY--------ILIASS
A0RY15_CENSY ------------GEFGILPILLSEQGEEQAA--KVGGAMARAAKGRD----S--MLIGSS
Y215_NITMS -----------SEKFKILPIILRDQSLEMAK--DVGNAVAQIAKSRN----T--MIVASS
Q2FTN8_METHJ ------------PRSRIVPLMMGHQTLQEVH--RISSIIITALEKYQ-KP-V--KIVASS
E1RIU4_METP4 ------------PDAKVVPVLMGRQTLQGAE--AMAEAIVRTVRETS-SD-V--RIVASS
Y890_AQUAE -----------RREFKILPIVVTFVEYEVAK--DFGRFLGEVLKEED----A--LIVISS
B5YIM6_THEYD -----------NPEAQIVPITLKMLSLKDCL--SLAQGIVLAVNELNFRDKV--VVVAST
Q74C45_GEOSL ------------SDVAIVPMCLGGGGYGWCR--QVGEGLARAIAAYG-EE-V--LIVASS
Q1IL90_KORVE ------------PNFRFVPVAVGTGRFDVLS--ALGESIAKVVQSAA-ER-V--MVIASS
Y1771_AERPE -----------GGDFRIVPIVVLHQTLDISI--RIARAYHRLREENG-VN-A--VLVATS
A2BMN4_HYPBU -----------GNNFKLVPIVVKEPSERMAR--EMAEAVKRAAEELG-RR-I--LVIASS
Y1438_METS3 ------------NDFKIVPVVLGSQTISAAN--DLAAAILKAGEKLD-KS-Y--CVIASS
Y539_PYRAB -----------GTDFRIVPITLGIQDEDVSE--ALGRAVFEAAEALG-RD-V--IVIAST
Y1626_PYRHO -----------GVEVKIVPITLGIQDEEVSR--SLGRSIFEASTSLG-RD-T--IIIAST
Y1638_PYRFU -----------GKDVKIVPITLGIQDEEVSY--ALGKAIYEASQELG-RD-I--VVIAST
Y132_THEON -----------RTDVRIVPITLGIQDEEVVE--DLGKAIYEAANELD-RD-V--VIIAST
Y1477_THEKO -----------GKEVKIVPITLGIQDEDVAE--DLGRAIFEASRELG-KD-V--VVIAST
Y1726_THEGJ -----------GKEVKIVPITLGIQDEDVSR--ALGKAIFEASEKLG-RD-V--VVIAST
Y605_THENN ------------GDFSIVPVCLMDQSPTVAE--DLAFAVRELMKSF--RN-V--LIIAST
Y837_THEP1 ------------GDVSIVPICLMDQSPAVAE--DLANALTKLVAEF--PS-V--LIIAST
Y087_THEMA ------------GEVSIVPICLMDQSPAVAE--DLASALAKLVAEF--PG-V--LIIAST
Y860_THESQ ------------GEVSMVPICLMDQSPAVAE--DLASALMKLAAEF--PG-V--LIIAST
Y2310_ARCFU ------------DDFKIVPICLGMQDEETAM--EVAEEILTAERETG-RK-V--VVIASS
Y2394_METBU -----------GSDFKVLPICMGMQDEDTAV--EVGLEVARAVKESG-KK-V--VFIASS
Y1422_METBF -----------DQDFRILPICLGMQDEETVI--EVGTLIANLVSKSG-KK-V--AFIASS
Y601_METAC -----------GRDFKILPICMGMQDKDTAV--EVGSLVADLVSESG-KR-A--VIIASS
Y1761_METMA -----------ERDFKILPICMGMQDEETAV--EVGNLLADLISESG-KR-A--VIIASS
Y403_METJA -----------IAKFKIVPICMMFQDYETAV--EVGYFIAKIAKELN-RR-I--VVIASS
Y697_METVS -----------IAKFKFVPISMSLQDYDTAV--GVGYMVAKVAKELN-RK-I--IIIASS
Y1387_METMP -----------IAKFKFVPISMMMQDYESCI--DVGYVIAKVARELN-RK-I--VIIAST
Y1286_METM6 -----------IAKFKFVPISMMMQDYETSI--DVGYFIAKVAKEMN-RK-I--IIIAST
Y191_METM5 -----------IAKFKFVPICMMMQDYETSM--DVGYFIAKVAKEMN-RK-I--IIIAST
Y632_METM7 -----------IAKFKFVPICMMMQDYETSM--DVGYFIAKVAKEMN-RK-I--IIIAST
Y045_METTH ------------DNFRIVPVTMWMQGHETAA--DVGHAVASAIRETG-RD-A--AVIAST
Y963_METKA -----------GESFRFVPVCMAMHDLQTAR--EVGEAIVDVAEELD-RN-T--VVIAST
Y1590_CALMQ ------------PGSRIVPIVLWNQTIDLSR--RLGSAISEVIDGRA-GE-V--VVVASS
Y028_PYRCJ ------------KNVKFVPIAVWRQTLSTSR--ELGKAIAKALREYK-RR-V--YLLASS
Y062_PYRAR ------------GDVRIVPIVVWRQTLSTSR--ELGKAVATAIREYG-RY-V--YVLASS
Y818_PYRAE ------------GDVKIVPIVMWRQTLSTSR--ELGRAIAKALKEYG-RK-A--YVIASS
Y1105_PYRIL ------------GDVKIVPITIWRQTLSTSR--ELGKALANAIREYG-RR-A--YIIASS
Y1357_DESA1 -----------GEDVKITPIVIGIHTPDIAR--DLAKSIYEASMSTG-KR-I--IVIASS
Y992_IGNH4 -----------GDSFRIVPIVMKVQTPSVAR--LLMQSIKEAMENLG-RD-Y--VVLSSS
Y2139_METS5 ------------DNLSILPVVILMQTPEIAE--FVAEGIWRFIQRHSDKD-I--VVLASS
Y066_SACS2 -----------DDNFKIVPIVIMMQTPEIAE--FLADAIYKVIQKYSDKD-I--VVLASS
Y2180_SULIY -----------DDDFKIVPIVIMMQTPEIAE--FLADAIYNVMQKNPDKD-I--VVLASS
Y2219_SULIL -----------DDDFKIVPIVIMMQTLEIAE--FLADAIYNVMQKNPDKD-I--VVLASS
Y2054_SULIM -----------DDDFKIVPIVIMMQTPEIAE--FLADAIYNVMQKNPDKD-I--VVLASS
Y2134_SULIA -----------DDDFKIVPIVIMMQTPEIAE--FLADAIYNVMQKNPDKD-I--VVLASS
Y2061_SULIK -----------DDDFKIVPIVIMMQTPEIAE--FLADAIYNVMQKNPDKD-I--VVLASS
Y739_SULIN -----------DDDFKIVPIVIMMQTPEIAE--FLADAIYNVMQKNPDKD-I--VVLASS
Y2062_SULTO -----------DSKTKIVPIVIMMQTPEISE--YLAEGISKIMQKYKDKD-I--VVIASS
Y089_SULAC -----------GQNFKIVPIVIMMQTPDVAE--SLAEGIYKLVSSGK-KD-I--VVLASS
. : :.
A2DWN3_TRIVA DFTHWGSRFSYTYL---------------------------------------PEKDGEI
A5K624_PLAVS DFCHYGRRFSFTNI-------------------------------------LQKYNDTHI
Q7RG18_PLAYO DFCHFGRRFSFT------------------------------------------------
Q6CB70_YARLI DFCHWGNNFRYWGY-------------------ADSENCDNVSQSREELRRALKRSNTPI
V5DRI1_TRYCR DFCHWGSRFQYKYH-------------------------------------YQKSEYPAI
MHO1_YEAST DFCHWGRRFQYTGY-------------VGSKEELNDAIQEETEVEMLTARSKLSHHQVPI
Q74ZF7_EREGS DFCHWGRRFGYTGY-------------VSSVEDIQDAVADGTEIETLTTRSKMDHHSIQI
I7ML70_TETTS DFCHWGQKFKYTYS---------------------------------------TKEDCEI
B8C1A5_THAPS DFCHWGKRFSYTPQ-------------------------------------PSREVANEV
YAY4_SCHPO DFCHWGRRFGYTLY---------------------LNDTNQLEDAVLKYKRRGGPTSPKI
MEMO1_CAEEL DFCHWGERFSFSPY--------------------------------------DRHSSIPI
MEMO1_DANRE DFCHWGQRFRYTYY-------------------------DE-------------SQG-EI
MEMO1_XENLA DFCHWGQRFRYTYY--------------------------------------DESQG-EI
MEMO1_XENTR DFCHWGQRFRYTYY---------------------------------------DESQGEI
MEMO1_BOVIN DFCHWGQRFRYSYY---------------------------------------DESQGEI
MEMO1_RAT DFCHWGQRFRYSYY--------------------------------------DESQG-EI
MEMO1_HUMAN DFCHWGQRFRYSYY--------------------------------------DESQG-EI
MEMO1_MACFA DFCHWGQRFRYSYY---------------------------------------DESQGEI
MEMO1_MOUSE DFCHWGQRFRYSYY---------------------------------------DESQGEI
MEMO1_DICDI DFCHWGERFGYTRY---------------------------------------ENKEVPI
Q5KH61_CRYNJ DFCHWGSRFSCTPYYPNIPPLANPVPPVKSSTSATPGTLTQPPELVKKFSSASSNPDVPI
I3XTV4_SULBS DLSHFHT-----------------------------------------------------
Q30PF9_SULDN DLSHFHT-----------------------------------------------------
E4TY61_SULKY DLSHYYN-----------------------------------------------------
C4L846_TOLAT DLSHYLS-----------------------------------------------------
I0IKV0_LEPFC DLSHYLP-----------------------------------------------------
D2S5D7_GEOOG DLSHHLD-----------------------------------------------------
D7GHE8_PROFC DLSHYHS-----------------------------------------------------
C4ZJW4_THASP DLSHYLS-----------------------------------------------------
B7J591_ACIF2 DLSHYHP-----------------------------------------------------
G8QLV8_AZOOP DLSHYQP-----------------------------------------------------
F9ZLF3_ACICS DLSHYLD-----------------------------------------------------
I3YH75_THIV6 DLSHYHD-----------------------------------------------------
Q727F8_DESVH DMSHYVT-----------------------------------------------------
E3H5Y6_ILYPC DFTHFHS-----------------------------------------------------
Q74NK0_NANEQ DFTHYGDIYGYKPF---------------------------------------SD-----
Y237_THEAC DFTHYED-----------------------------------------------------
Y1383_THEVO DFTHYER-----------------------------------------------------
A0RY15_CENSY DLTHYES-----------------------------------------------------
Y215_NITMS DFTHYEE-----------------------------------------------------
Q2FTN8_METHJ DFSHYVS-----------------------------------------------------
E1RIU4_METP4 DFSHYIP-----------------------------------------------------
Y890_AQUAE DMSHYVP-----------------------------------------------------
B5YIM6_THEYD DMSHYLP-----------------------------------------------------
Q74C45_GEOSL DMTHYES-----------------------------------------------------
Q1IL90_KORVE DMNHYEN-----------------------------------------------------
Y1771_AERPE DLNHYEP-----------------------------------------------------
A2BMN4_HYPBU DFTHHGYMYDYVLF---------------------------------------TENV---
Y1438_METS3 DLSHFNT-----------------------------------------------------
Y539_PYRAB DFMHYGSFYGYVPF---------------------------------------RGRANEL
Y1626_PYRHO DFMHYGSFYGYVPF---------------------------------------RGRPEEL
Y1638_PYRFU DFMHYGEFYGYVPF---------------------------------------RARADEL
Y132_THEON DFMHYGPAYGYVPF---------------------------------------RARADEL
Y1477_THEKO DFMHYGQIYGYVPF---------------------------------------RARADEL
Y1726_THEGJ DFMHYGPAYGYVPF---------------------------------------RARADEL
Y605_THENN DLNHYED-----------------------------------------------------
Y837_THEP1 DLNHYED-----------------------------------------------------
Y087_THEMA DLNHYED-----------------------------------------------------
Y860_THESQ DLNHYED-----------------------------------------------------
Y2310_ARCFU DMHHYLP-----------------------------------------------------
Y2394_METBU DLSHYVP-----------------------------------------------------
Y1422_METBF DFTHYQP-----------------------------------------------------
Y601_METAC DFTHYET-----------------------------------------------------
Y1761_METMA DFTHYET-----------------------------------------------------
Y403_METJA DLTHYEP-----------------------------------------------------
Y697_METVS DFSHYEP-----------------------------------------------------
Y1387_METMP DFSHYEP-----------------------------------------------------
Y1286_METM6 DFSHYEP-----------------------------------------------------
Y191_METM5 DFSHYES-----------------------------------------------------
Y632_METM7 DFSHYEP-----------------------------------------------------
Y045_METTH DFTHYSP-----------------------------------------------------
Y963_METKA DFTHYEP-----------------------------------------------------
Y1590_CALMQ DLNHYEP-----------------------------------------------------
Y028_PYRCJ DFNHYEP-----------------------------------------------------
Y062_PYRAR DFNHYEP-----------------------------------------------------
Y818_PYRAE DFNHYEP-----------------------------------------------------
Y1105_PYRIL DFNHYEH-----------------------------------------------------
Y1357_DESA1 DFNHYEP-----------------------------------------------------
Y992_IGNH4 DLNHYEP-----------------------------------------------------
Y2139_METS5 DLNHYDP-----------------------------------------------------
Y066_SACS2 DMNHYDP-----------------------------------------------------
Y2180_SULIY DMNHYDP-----------------------------------------------------
Y2219_SULIL DMNHYDP-----------------------------------------------------
Y2054_SULIM DMNHYDP-----------------------------------------------------
Y2134_SULIA DMNHYDP-----------------------------------------------------
Y2061_SULIK DMNHYDP-----------------------------------------------------
Y739_SULIN DMNHYDP-----------------------------------------------------
Y2062_SULTO DMNHYEP-----------------------------------------------------
Y089_SULAC DLNHYEP-----------------------------------------------------
*: *
A2DWN3_TRIVA WEKISAIDHGAMEAI----STC-----KAKNFQDYIKSTRATICGRNPITIAMMAFD---
A5K624_PLAVS FKQVENMDRDAASII----SRH-----DIADFIEYLNKTHNTICGSNPIKMMLQLLQ---
Q7RG18_PLAYO NILEKYNDKYIHKKI----ENM-----DKDGINVI-------------------------
Q6CB70_YARLI YKSIEYLDKKGMEVA----SLT-----SYDKWKEYCKKTDNTICGRKPLAILISMLENYA
V5DRI1_TRYCR ADAIIAMDHEGMEWL----EKR-----DMNGWYEYLNKTHNTICGRRPISIGMEAVK---
MHO1_YEAST WQSIEIMDRYAMKTLSDTPNGE-----RYDAWKQYLEITGNTICGEKPISVILSALSKIR
Q74ZF7_EREGS YKSIELLDRYAMDIL----GQMADSREKYQIWKDYLEVTGNTICGEKPIGVLLCAFS---
I7ML70_TETTS YEQIEKLDQKGMEHI----EMN-----DIDAFQQYIRETENNICGRHAISILMNAIA---
B8C1A5_THAPS HEYIEYLDRKGMSLI----EMQ-----RPGAFADYLREYSNTICGRHPIAVWLNTVVTNR
YAY4_SCHPO YESISNLDHIGMKII----ETK-----SSDDFSEYLKTTQNTICGRYPIELIMKSME---
MEMO1_CAEEL YEQITNMDKQGMSAI----ETL-----NPAAFNDYLKKTQNTICGRNPILIMLQAAEHFR
MEMO1_DANRE YRSIEHLDKMGMGII----EQL-----DPISFSNYLKKYHNTICGRHPIGVLLNAVAELK
MEMO1_XENLA YRSIENLDKMGMSII----EQL-----DPVQFSNYLKKYHNTICGRHPIGVLLNAATELQ
MEMO1_XENTR YRSIENLDKMGMGII----EQL-----DPVQFSNYLKKYHNTICGRHPIGVLLNAAT-EL
MEMO1_BOVIN YRSIEHLDKMGMSII----EQL-----DPVSFSNYLKKYHNTICGRHPIGVLLNAIT---
MEMO1_RAT YRSIEHLDKMGMSII----EQL-----DPVSFSNYLKKYHNTICGRHPIGVLLNAITELQ
MEMO1_HUMAN YRSIEHLDKMGMSII----EQL-----DPVSFSNYLKKYHNTICGRHPIGVLLNAITELQ
MEMO1_MACFA YRSIEHLDKMGMSII----EQL-----DPVSFSNYLKKYHNTICGRHPIGVLLNAIT-EL
MEMO1_MOUSE YRSIEHLDKMGMSII----EQL-----DPVSFSNYLKKYHNTICGRHPIGVLLNAIT-EL
MEMO1_DICDI YKYIEELDRKGMEII----ESG-----DPVQFSKYLKETKNTICGRCPIAVMLWITK---
Q5KH61_CRYNJ WKSIEYMDHEGMDLLRKPGEDG-----AVEKWHGYLERTKNTICGRNPITVLLNLVQFVY
I3XTV4_SULBS EEEANRRDTFCINAI----NTL-----DLHAL------ENCEACGKLGVKALVHSAR---
Q30PF9_SULDN QEEALRVDNICVSAI----ENL-----DIEKLHS-----GCEACGIIGVEAMLLSAK---
E4TY61_SULKY LSQAQQLDSICLEAI----REE-----DSDKLHQ-----GCEACGMIGVEAMLNIAK---
C4L846_TOLAT KDIAELQDDYTIRQI----LQF------------SETLTGDQACGCYALNGALHWAH---
I0IKV0_LEPFC PDEGQLLDARTASDI----ISP-----EYRPLTNEM------ACGSQPLNGFLMAAQ---
D2S5D7_GEOOG EPSARERDRRTADAV----LAR-----DAAALRPD------DACGHQPLRGPLHHAA---
D7GHE8_PROFC YDDARKLDAGTIDKV----LAL-----DDT-------VAPNRACGCFSLNGLLLASG---
C4ZJW4_THASP YREAQWSDRAAVDQV----LEL------RPGLDHE------QACGATPINGLLLAAR---
B7J591_ACIF2 YAEARAIDHHTVEEI----LRF-----DPTPIDHE------QACGATPINGLLPVAR---
G8QLV8_AZOOP YAEAERLDQATCARI----AAA-----RAD-LAPQ------EACGAIPINGLLLAAA---
F9ZLF3_ACICS YATAQRLDARTAEII----EAL-----QPEAIHYE------QACGRIPLGGLLELAR---
I3YH75_THIV6 DRSARRLDAATSAAI----ESL-----RPDDIGYD------QACGRTPVNGLLTVAK---
Q727F8_DESVH RTQAEERDALALGRM----AAL-----DPEGLYATVRHNRITMCGVLPAVVALHACR---
E3H5Y6_ILYPC SEEGAKLDSYAIESL----LKM-----DSGEFQDRILEKDISICGMGPIMVLLEYSK---
Q74NK0_NANEQ GRKVKELDMKLISYI----LKL-----DSLGFYKEIVRTGATVCGWGPIVSVIEFAK---
Y237_THEAC AKRVEKKDMDLISAI----LTL-----DLDKFYSVLEKENVTACGYGAIAALMYYTK---
Y1383_THEVO SDIVERKDMDLISRI----VDL-----DIDGFYDTIERENVTACGYGAIAILMIIAK---
A0RY15_CENSY NAFAHEQDGALIEAI----LSM-----DTVKFYAVLRERKVSACGYGAIAATMAASI---
Y215_NITMS NSFAHSQDKALIEPI----LEM-----DVEKFYSVLMEKRVTACGYGAMASVMIACK---
Q2FTN8_METHJ AEKAYRDDHYAIEAL----LQM-----NVPEFFSRIQSHNITACGYGPIGCMMEVLR---
E1RIU4_METP4 DEEARRLDGYAIEAL----FDL-----DSEEFFRRIREEGVSACGYGPIAVMVEACR---
Y890_AQUAE AEEARKKDEILISAM----ERL-----NTEELYFKAVQYNITMCGVVPAVVGIESAK---
B5YIM6_THEYD DELARKVDSLAVEKI----RHF-----DPEGLYNTVLEHGISMCGFVPTVTMLYTTK---
Q74C45_GEOSL AESARLKDEAALSCV----LAL-----DAEGLLKVCRQRGITMCGVIPSTVMLVAAR---
Q1IL90_KORVE DADTRVKDRLAIERL----LAL-----DAKGLYDVVHEKNISMCGYGPAVAMLTAAK---
Y1771_AERPE YEENKRKDLLLLKAI----EEG-----DPEAVFKTIEAHAISACGPSPIAAAVEAGR---
A2BMN4_HYPBU RENVAKLDMAIIEHI----LRL-----DTKGFLETIYRYGATVCGYGAIATLIEYAK---
Y1438_METS3 QERANKVDGFVLEDI----ENM-----DEFKLLEEIIQYNITMCGYGPVMTTMILSK---
Y539_PYRAB PNMVKEWDMRIIRRI----LDF-----DLKGMFEEIREMDHTMCGPGGVGAGIVYSR---
Y1626_PYRHO PNMVRDWDMRIIRRI----LDF-----DLDGMFSEIREMNHTMCGPGGVGAGIIYSR---
Y1638_PYRFU PNLVKEWDMRVIRRI----LDF-----DVEGMFEEINAMNHTMCGPGGVGVGIVYSK---
Y132_THEON PHRVKEWDFRVIQKI----LDF-----DVKGMFGELRKMDHTMCGPGGVGTAIVYSR---
Y1477_THEKO PHRIKEWDFRIIRRI----LDF-----DVRGMFEEIREMNHTMCGPGGVGTAIVYSR---
Y1726_THEGJ PHRIKEWDFRLIRRI----LDF-----DVDGLFRELREMRHTMCGPGAVGTAIVYSR---
Y605_THENN QKTTLKKDYLVVEAI----EKR-----DSRLLYEYLVKEDISMCGYGGVAVLLNL-----
Y837_THEP1 QRTTLRKDSYIMEAI----RNK-----DPRLLYEYLVKEDISMCGYGGVATLLNM-----
Y087_THEMA QRTTLRKDSYIIEAI----EGM-----DPSLLYEYLVREDISMCGYGGVATLLNM-----
Y860_THESQ QRTTLRKDSYIIEAI----KSN-----DPRLLYEYLVKEDISMCGYGGVATLLNM-----
Y2310_ARCFU DEECRRLDSIVIDAI----LSM-----DVKKYYETIYRLQASVCGYGCIAVAMYYSK---
Y2394_METBU QEKAEKSDNYLIDAI----LDM-----DVPEIYRRKYEKDITACGYGPITAMLTAAK---
Y1422_METBF ANLARETDNEIIEAI----LNL-----DVPGIYERLYRRNASVCGYGPISAMLTASK---
Y601_METAC AEHARETDSEVIDAI----LKL-----DVPGMYDSLYRRNASVCGYGPIAAMLSASQ---
Y1761_METMA AERAKEIDSEVIDSI----LNF-----DISGMYDRLYRRNASVCGYGPITAMLTASK---
Y403_METJA QEIASKKDAIVIKDI----LEM-----NEKELYEDVVNYNISMCGYGPVIAMLKAMK---
Y697_METVS EEIASKKDAIIIKDI----LKM-----EEEEIFTDVVTNNVTMCGYGPIIAMIKAMK---
Y1387_METMP QEQASKKDAVVIKDI----LEL-----NDEEIFTDVVTHTISMCGYGPVIAMVKAMK---
Y1286_METM6 QESASKKDAIVIKDI----LEL-----KDEEIFIDVVTHNISMCGYGPVIAMVKAMK---
Y191_METM5 QESASKKDALVIKDI----LEL-----KDEEIFTDVVTHNISMCGYGPVIAMIKAMK---
Y632_METM7 QESASKKDALVIKDI----LEL-----NDEEIFTDVVTHNISMCGYGPVIAMVKAMK---
Y045_METTH QDIAEATDRRIIDRI----TAM-----DDTGMYGVISELNATMCGYGPVAATIIASR---
Y963_METKA HDQAQKKDRKVIERI----TAL-----DEAGMIEIVERYNVSMCGVGPTAATIVAVK---
Y1590_CALMQ HEVTTDKDMKVIERI----LNM-----DEEGFYTVMDKYDVSVCGFGAIMTAIVYSR---
Y028_PYRCJ HDVTVKKDDMAIGKI----LEL-----DEAGLFDVASRFDISICGIGPIASVIVAAK---
Y062_PYRAR HEVTVQKDDMAISKI----LKV-----DEAGLFEVASKFDISICGLGPIGALIVIAK---
Y818_PYRAE HDITTRKDEMAISKI----LKL-----DEAGLFEISSKFDISICGIGPIGVLIAAAK---
Y1105_PYRIL HDITTKKDEMAIGKI----LQL-----DETGLFEVASKFDISICGIGPIGALIVAAK---
Y1357_DESA1 HEETSRKDSMAIDRI----LKL-----DTDGLYNVILHNDISICGPGGIMTLMEYTK---
Y992_IGNH4 HDITVEKDMLALEKI----VNL-----DPEGLQEVLVKYDISMCGPGPVMVNMYLDK---
Y2139_METS5 HDVTMTKDELVIRKI----QDM-----DYKGLYKVVEEYDVTVCGYAPIMASLILAK---
Y066_SACS2 HEITMKKDEEAIEKI----QQL-----DYRGLYEVVEGKDVTLCGYGPIMVSLILAK---
Y2180_SULIY HEITVKKDVEAIEKI----QQL-----DYKGLYEVVEGKDVTLCGYGPIMVNLILAK---
Y2219_SULIL HEITVKKDVEAIEKI----QQL-----DYKGLYEVVEGKDVTLCGYGPIMVNLILAK---
Y2054_SULIM HEITVKKDEEAIEKI----QQL-----DYKGLYEVVEGKDVTLCGYGPIMVNLILAK---
Y2134_SULIA HEITVKKDEEAIEKI----QQL-----DYKGLYEVVEGKDVTLCGYGPIMVNLILAK---
Y2061_SULIK HEITVKKDEEAIEKI----QQL-----DYKGLYEVVEGKDVTLCGYGPIMVNLILAK---
Y739_SULIN HEITVKKDVEAIEKI----QQL-----DYKGLYEVVEGKDVTLCGYGPIMVNLILAK---
Y2062_SULTO HEKTIEKDNMAIEKI----LSL-----DYKGLFNVVEEKDVTACGFGPMMTVLMLAK---
Y089_SULAC HDKTIEKDNLAIDEI----QKL-----DYKGLFRVVEEKDVTACGYGPIMTVLILAK---
*
A2DWN3_TRIVA -----KPYRVDWPHYSQSSHAKNMADSSVSYAGGVIRFV--------
A5K624_PLAVS --DLPGKVSTKLMHYSQSNQARSANDSSVSYAGMVSFIN--------
Q7RG18_PLAYO -----------------------TKHNVQGYLN--------------
Q6CB70_YARLI IEKGDKPISLEWIGYSQSNQVRDISEGSVSYASGFALLR--------
V5DRI1_TRYCR --ND-RSTTVRFLHYSQSNRCASLSDSSVSYASALITHR--------
MHO1_YEAST DAGP-SGIKFQWPNYSQSSHVTSIDDSSVSYASGYVTIG--------
Q74ZF7_EREGS --YVNTPLSFHWCGYSQSSEVKSLEDSSVSYAAGYCIF---------
I7ML70_TETTS KSKISNQIDTKFIRYSQSSLVRDKNDSSVSYAAAVSIITE-------
B8C1A5_THAPS EEGK-ERLDVRFAKYAQSGKATSLRDFSVSYASAVARTANS------
YAY4_SCHPO --CANFSERFKFISYAQSSHVELVTDSSVSYATATA-----------
MEMO1_CAEEL ISNN-HTHEFRFLHYTQSNKVRSSVDSSVSYASGVLFVHPN------
MEMO1_DANRE -KNG-IDMNFSFLNYAQSSQCRNWSDSSVSYAAGALIVH--------
MEMO1_XENLA -KNG-VNMSFSFLNYAQSSQCRSWQDSSVSYAAGALVVH--------
MEMO1_XENTR QKNG-VNMSFSFLNYAQSSQCRSWQDSSVSYAAGALVVH--------
MEMO1_BOVIN --EL----QKNGMNMSFSFFQQASWRRRMGAAAV-------------
MEMO1_RAT -KSG-MNMSFSFLNYAQSSQCRSWQDSSVSYAAGALTVH--------
MEMO1_HUMAN -KNG-MNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH--------
MEMO1_MACFA QKNG-MNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH--------
MEMO1_MOUSE QKNG-MNMSFSFLNYAQSSQCRSWQDSSVSYAAGALTVH--------
MEMO1_DICDI --NSQFKYNISSLYYEQSSKVIKSSDSSVSYGVLSFTKEN-------
Q5KH61_CRYNJ KNQP-VKPEFVFVRYEQSSKCVNGKDSSVSYVSGVLRLPQ-------
I3XTV4_SULBS ---L-HAFKPYFLDYRTSYARSGDASRVVGYTSFVLGCAT-------
Q30PF9_SULDN --K--ATLVPHLLDYRTSADASGDESRVVGYVSVYFAE---------
E4TY61_SULKY --K--RDLKNIILDYRTSADASQDTSRVVGYASVLFY----------
C4L846_TOLAT --Q--QQLDIKLLAKCNSGDTSHDKERVVGYAAFALY----------
I0IKV0_LEPFC --E--AGLKGEILDLRNSGDTAGPKNEVVGYGSFAFWSP--------
D2S5D7_GEOOG --E--RHLSVELLRMATSADSGAGRARVVGYGAFLLREAAGGRTS--
D7GHE8_PROFC --E--HHLTPTLLSARNSGDTAGDKGRVVGYASFAFQADQ-------
C4ZJW4_THASP --K--HDLQAHLLDLRNSGDTAGDRSRVVGYTSIAFCEAEPPSHARH
B7J591_ACIF2 --K--HHLHPRLVGLCNSGDTAGSRDAVVGYAAVAFYGESHDHTGR-
G8QLV8_AZOOP --R--HGLRPRLLDRRNSGDTAGDRERVVGYAAFALEPDHGPH----
F9ZLF3_ACICS --K--RHMRIERVDLRNSGDTTGPRDQVVGYGAWVLYEDAA------
I3YH75_THIV6 --R--RGMQARTLDLRNSGDTAGSRDQVVGYGAYVFH----------
Q727F8_DESVH --AL-GAESACLAAYDTSASASGDHERVVGYAGMVAKRPAA------
E3H5Y6_ILYPC --MILKNPKLEILKRGHSGEVY-PSDEVVDYVSILVYEE--------
Q74NK0_NANEQ --ER-G-LEPILLDYYTSGDVTGDYSLVVGYASIIFV----------
Y237_THEAC --KR-G-GRMIFLNHSNSGDVTGDYSEVVGYASLVSVIP--------
Y1383_THEVO --KI-G-AKISLLNHSNSGDVTNDYDEVVGYSSIVACRQI-------
A0RY15_CENSY --EL-GATKGTLLKYATSGDITGDEQSVVGYCSIVFS----------
Y215_NITMS --NL-GAVKGELLSYTTSGDVMGDTSSVVGYGAIKFI----------
Q2FTN8_METHJ --TR-GKTRCDLLEYTTSGETSGDYDQVVGYAALAVR----------
E1RIU4_METP4 --ELFGAKKSELLKYMTSGDVSGDFSQVVGYAAVAVF----------
Y890_AQUAE --VL-GATKGIVVDYSNSGDTTGDYSQVVAYLGMIFL----------
B5YIM6_THEYD --LL-GAKEIQVIKYTTSAEVSRDYDKVVGYLGAIVY----------
Q74C45_GEOSL --EL-GASRAELIRYGTSGDVTGDNRQVVAYAAVAVY----------
Q1IL90_KORVE --RV-GASRAELIKYATSGDVSGDRDMVVGYAGIAVL----------
Y1771_AERPE --LA-G-VKPRVLAYANSGDVTGEKAWVVGYPAVRV-----------
A2BMN4_HYPBU --LE-G-ARAKLLKYYNSADVTGDEAAVVGYAAILFHL---------
Y1438_METS3 --MC-GKNTSEILAYKTSGDISGDLSSVVGYASGIFK----------
Y539_PYRAB --LM-NAREAELLHYTTSFEVSRSTDAIVGYASIVMRR---------
Y1626_PYRHO --LM-KAKEAELLHYTTSFEVSRSPDAIVGYASIIMKR---------
Y1638_PYRFU --LA-GAIEAELLHYTTSFEVSRSTDAIVGYASIVMRKA--------
Y132_THEON --LA-GALEAELLHYTTSFEVSRSTDAIVGYASIVFRK---------
Y1477_THEKO --LA-GAVEAELLHYTTSFEVSRSTEAVVGYASIVFRR---------
Y1726_THEGJ --LA-GAVEAELLHYTTSYEISRSTEAVVGYASIVMRR---------
Y605_THENN -----GFSSVRILKHATSGDVSGDTLEVVGYLSAILS----------
Y837_THEP1 -----NFKNARILKHATSGDVSGDKLEVVGYLSAILF----------
Y087_THEMA -----DFENVRILKHATSGDVSGDTLEVVGYLSAILF----------
Y860_THESQ -----NFKNARILKHATSGDVSGDKLEVVGYLSAILF----------
Y2310_ARCFU --AK-GA-RAELVDYSTSGDVA-DRSQVVGYAGIVFRV---------
Y2394_METBU --EC-GAKNTELVKYGTSGDVTGD-PMVVGYAAIIVK----------
Y1422_METBF --KL-GATRAELLNYSNSGEVSGDMNAVVGYAAIIVE----------
Y601_METAC --KL-GGSRATLLEYANSGDVSGDMSAVVGYAAIIVE----------
Y1761_METMA --KL-GGSRATLLKYANSGDVSGDKDAVVGYAAIIVE----------
Y403_METJA --TL-GAEKAKLLAYATSGDITGDYSAVVGYASAIVE----------
Y697_METVS --VL-GAKESKLLSYSTSGDVTKDYSEVVGYGALIIE----------
Y1387_METMP --DL-GARTSYLLYYSTSGDVTKDYSEVVGYASLLIK----------
Y1286_METM6 --DL-GAKTANLLYYSTSGDVTKDYSEVVGYASILVK----------
Y191_METM5 --DL-GAKNSNLLYYSTSGDVTKDYSEVVGYASILVK----------
Y632_METM7 --DL-GATNSNLLYYSTSGDVTKDYSEVVGYASILVK----------
Y045_METTH --IL-GATECDLLRYATSGDVTGDRSSVVGYAHLS------------
Y963_METKA --AM-GASEGELLKYATSGDVSGDYSQVVGYAAIVFRRG--------
Y1590_CALMQ --KQ-GSTGVKLLKHATSGDTSGYLLETVGYASIAFYK---------
Y028_PYRCJ --EL-GFSNAALLKHATSGDTSGYRDETVGYASILFYK---------
Y062_PYRAR --EL-GFGNVTLLKHATSGDTSGYKDETVGYASILFHR---------
Y818_PYRAE --EL-GYINVTLLKHATSGDTSGYKDETVGYASILFYR---------
Y1105_PYRIL --EL-GYKNVTLLKHATSGDTSGYREETVGYASIIFYR---------
Y1357_DESA1 --KL-G-GKAQLLKYATSGDTSGDYSHVVGYAALKFYI---------
Y992_IGNH4 --EY-GAERAILLKHATSGDTSGDKSAVVGYAAVKFPLP--------
Y2139_METS5 --KM-H-KKPYILKHATSGDTSGDKSSVVGYLATRFSD---------
Y066_SACS2 --KL-G-KKAYILKHATSGDTSGPKDSVVGYLAARFGS---------
Y2180_SULIY --KF-G-KKAYILKHATSGDTSGPKDSVVGYLAARFGS---------
Y2219_SULIL --KF-G-KKAYILKHATSGDTSGPKDSVVGYLAARFGS---------
Y2054_SULIM --KF-G-KKAYILKHATSGDTSGPKDSVVGYLAARFGS---------
Y2134_SULIA --KF-G-KKAYILKHATSGDTSGPKDSVVGYLAARFGS---------
Y2061_SULIK --KF-G-KKAYILKHATSGDTSGPKDSVVGYLAARFGS---------
Y739_SULIN --KF-G-KKAYILKHATSGDTSGPKDSVVGYLAARFGS---------
Y2062_SULTO --KF-N-KKPYVLKHATSGDTSGDKSSVVGYLSVRFGD---------
Y089_SULAC --KL-G-KKPYVLRHATSGDTSGDKSSVVGYLSVRFGD---------