HAMAP data

                CLUSTAL format seed alignment for MF_00078

_____________________________________________________________________________

Features found in the protein:The following colors are used to highlight features:blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
magenta is used to display DISULFID, THIOLEST and THIOETH.
red is used for all other features, such as INIT_MET, ACTIVE SITE,
 METAL,BINDING, NP_BIND, SITE, REGION, etc.
The ID of the sequence used as the template for feature propagation is 
underlined.
A '<' at the beginning of a sequence or '>' at the end indicate that
 the protein is fused with another domain either at the N- or C-terminus._____________________________________________________________________________

PMDHS_METAC       --------MVPIKLKGRTISRGCAEGEILISRDP--ISFLGSVDPKTGIVVEEKHSLAGK
PMDHS_METMA       --------MIPIKFKGRTISRGCAEGEVLISRDP--ISFLGSVDPRTGIVVEEKHSLAGK
Q46EJ6_METBF      --------MIPIKLKGRTISRGCAKGEVLLSRDP--ISFLGNVDPKTGVVIEENHALEGK
D5E7X8_METMS      --------MVPIRIKGRGISKGSAGGEVLLSEDP--ISFLGNVDPQTGKIVDPDHCLFGK
PMDHS_METBU       --------MVTIKIECRTIARGVAEGEVLLSEDA--LSFLGNVDPKTGVVVDPGHAIYGE
D7EBP1_METEZ      --------METTKINCRKISRGVAEGEVLITDNS--ISFLGNVDPESGIVVEPGHELYNK
PMDHS_METAR       -----------MQIKGHRICGGRATGPALVSKDA--ISFLGGVDPGTGTVIEKGHALYGK
D1Z109_METPS      -----------MILKGRTVSRGKAAGPALVSKDA--ISFLGGVDPKTGNVIEKGHALYGR
PMDHS_METTP       -----------MEIKCHRVSGGCAEGPALVTRER--ISFLGNVDPETGVVVDPAHELYGR
PMDHS_PYRAB       -----------MKLKGKGVGKNIVEGEVIVSKKP--LSFLGGVDPETGIIIDPDSDIKGE
PMDHS_PYRHO       -----------MKLKGKGIGKVVVEGEVIVSRKP--LSFLGGVDPETGTITDPESDIKGE
PMDHS_PYRFU       -----------MKLKGRGIVKGVAEGELVVSRKP--LSFLGGVDPNTGIITDPESDIQGE
PMDHS_THEGJ       -----------MKLRGRKVVGGKAEGELIVSKKP--LSFLGGVDPETGIVTDAESDIRGQ
PMDHS_THEON       -----------MKLKGRKIVGGKAEGELIVSQKP--LSFLGGVDPNTGIVTDAESDIRGQ
PMDHS_THEKO       -----------MKLKGRKIVGGKAEGEVIVSRKP--LSFLGGVDPETGIVTDAESDIRGQ
PMDHS_THESM       -----------MRLKGRKIFGGKVRGTALVSRRP--LSFLGGVDPNTGVIIDVESDIRGE
F0LM22_THEBM      -----------MKLKGRRITKGKAKGIALVSRRP--LSFLGGIDPKTGIITDVESDIRGE
PMDHS_METJA       -----------MELKGRSISKGIIEGIAIVSKKP--FSFLGGVD-EEGNIIDKDSDLYGQ
D3S7M2_METSF      -----------MELKGRSISKGLIEGIAIVSKKP--FSFLGGVD-EEGNIIDKDSDLYGQ
C7P5U0_METFA      -----------MELKGRAISKGVVEGIAIVSKKP--FSFLGGVD-EDGNIIDKDSDLYEE
C9RI90_METVM      --------MIIVELKGRGISKGKVEGIAIVSKKP--FSFLGGVN-KDGDIIDKNSDLYGQ
D5VQM1_METIM      -----------MILKGRVISKGYVEAELLVSKKP--FSFLGGVD-KEGNVIDKESDIYGE
A4FXT5_METM5      ----------MKELNGRIISKGVVEGEAIVSKSS--ISFLGGVN-EEGIVTDKENELFGK
A9AB42_METM6      ----------MKELNGRIISKGVVEGEAIVSKSS--ISFLGGVN-EEGIVTDKENELFGK
A6VFJ3_METM7      ----------MKELTGRIISKGVVEGEAIVSKSS--ISFLGGVN-EEGIVTDKENELFGK
Q6LYT5_METMP      ----------MKELNGRIISKGVVEGEAIISKSP--ISFLGGVN-EEGIVTDKENELFGK
A6UN62_METVS      ----------MKELKGRIISKGIVEGEAIISKSP--VSFLGGIN-EEGIVTDKENELFGK
D7DTY0_METV3      ------MGDNLEELKGRIISKGYTEGEIIISNSP--ISFLGGVS-EEGVITDKENELYGE
A6UU66_META3      --MNNIESTEYIELKGRIISKGYIEAEAIVSEES--ISFLGGVN-EEGVITDKDSKLNGQ
D3S160_FERPA      -----------MRIKARGVSKGFARGEALVSKSK--ISFLGDVDAKSGVVVDKNSDIYGE
D2RHH9_ARCPA      -----------MRIRGRVISKGYAEGEVIVSRRK--FSFLGDVDVESGVVVAEDSDISGE
PMDHS_ARCFU       -----------MKFACRAITRGRAEGEALVTKEY--ISFLGGIDKETGIVK-EDCEIKGE
PMDHS_METTH       -----------MEVDCRVISRGKGRGPVLVSTEP--LSFLGGVDPGTGRVIDQKHPLHGR
D9PU24_METTM      -----------MEISCRIISRGRGKGPVIISDKP--LSFLGGVDPGTGTVIDPRHPLHGR
F0T6M3_METLA      --------MDPKIINCRKISKGITSGEVIITRDS--LSFLGGVNPDTGEIIDSKHELFGK
D3DZ99_METRM      ------------MIECRNISKGKAEGELIVSDEA--ISFLGGVDPETGVVIDPNHELKGQ
A5UMD2_METS3      ------------MIDCRNIAKGKDSGELIVSSEP--ISFLGGVDPKTGIVIDPNHELKGQ
Q2NHJ1_METST      ---------MSSNIKCRIISKGKDSGNALVTKDP--ISFLGGVDPKTGIVIDKKHELYNE
E3GYB3_METFV      -------------MNVRVISKGNAKGKPLVSNEP--LSFLGGVDPKTGKVIDPRHPLKGK
A7I8B4_METB6      MIIFNHLCGVILLITGRSISRGRGTGKLLVSPEP--ISFLSGVDPETGIVVEKGHPLEGT
A3CV39_METMJ      -------------MQGRSISRGIGTGELLVSSEP--ISFLSGVDPETGIVVEHGHPLEGQ
Q2FUD8_METHJ      -----------MIIQGRGISRGIGKGPLLIGPDP--ISFLSGVDPETGIVLEPGHPLEGK
E1RJU7_METP4      --------------MARGISGGKGTGELLVSGEA--ISFLSGVDPETGIVIESGHPLEGK
B8GKJ6_METPE      -------------MQGRGIAKGSGSGELLVSEAP--ISFLSGVDPVTGVIIEQGHPLQGR
A2SRL5_METLZ      -----------MLIQGRSIAKGTGTGPLLITDTP--ISFLGGVDPKTGIVIDETHPLFGK
C7NT80_HALUD      MSSESSDSAAEGAIDAEPITEGQGRGEVLRSDVP--ISFYGAVEPDTGEFIEDGHPLEGE
PMDHS_AERPE       --------MEVLRYRSRPIVGGEAEGPAVVIDS---LSFYGEVDPETGVTSG------GK
D9PZT3_ACIS3      ---------MTMELRGRQLVPGRAAGQAVVMDA---LSFYGDVDPHTGRTPD------GR
PMDHS_METKA       --------MSVSPVRCEPVVDVEEPVEAEVLVSSQRLSFLGGVDPKTGEVVDPSHELCGE
                                  . :                 .** . :.   *            

PMDHS_METAC       SIKGKVLVFPHGKGSTVGSYVMYQLKKNGAAPVAIINLETEPIVAVGAIISEIPLVDMLE
PMDHS_METMA       SIKGKVLVFPHGKGSTVGSYVMYQLKKNEAAPAAIINLETEPIVAVGAIISEIPLVDMLE
Q46EJ6_METBF      SIQGKVLVFPHGKGSTVGSYVMYQLKKNGTAPAAIINLETEPIVAVGAIISEIPLVDMLE
D5E7X8_METMS      KIGGKVLVFPHGKGSTVGSYVIYQLFKNGVAPVAMVNLECEPIVAVGAIISEIPLVDGLE
PMDHS_METBU       CIRDKILVFPHGKGSTVGSYVIYQLKKNNVSPAAMINIDSEPIVAVGAIISDIPLVDRLD
D7EBP1_METEZ      SIKDKVLVFPQGKGSTVGSYVLYQLSKNDVAPAAMINIESEPIVAVGAIISGIPLVDKLE
PMDHS_METAR       NVKGTVLIFPGGKGSTVGSYVIYQLMKNGVAPAAMINIKAEPIVAVGAIISGIPMVDRLE
D1Z109_METPS      NVKGTVLVFPGGKGSTVGSYVIYQLKKNGVAPAAIINIRSEPIVAVGAIISDIPMVDALD
PMDHS_METTP       SIAGVVLIFPGGKGSTVGSYVIYQLRKRGMAPAAMINLKSEPIVAVGAIISDIPLVDRVP
PMDHS_PYRAB       SIEGKILVFPKGRGSTVGSYVIYALSRNGKAPKAIIVEEAEPIVTVGAIISGIPLIAGVD
PMDHS_PYRHO       SITGKILVFPKGKGSTVGSYILYALSKNGKGPKAIIVEEAEPIVTAGAIISGIPLITNVD
PMDHS_PYRFU       KITGKILAFPRGKGSTVGSYVIYALAKKGTGPKAIIVEEAEAIVAVGAIIAGIPLVTGID
PMDHS_THEGJ       SIAGKILAFPRGKGSTVGSYVIYALKKNGKAPKAIIVGEAETIVATGAIIAGIPMVQGID
PMDHS_THEON       SIAGKVLAFPRGKGSTVGSYVIYALKKNGKAPKAIIVGEAETIVATGAIIAGIPMVDGID
PMDHS_THEKO       SIAGKILVFPRGKGSTVGSYVIYALKKNNKAPKAIIVGEAETIVATGAIISDIPMVDGVD
PMDHS_THESM       NVKDKILVFPRGKGSTVGSYIVYQLKKNGVAPKAIVVEEAETIVATGAIIAGIPMVDKID
F0LM22_THEBM      SVKDKILVFPRGKGSTVGSYIIYQLKKNNVAPKAIVVEDAETIVATGAIIAEIPMVDRID
PMDHS_METJA       SLKGKIFVFPYGRGSTVGSYVIYGLAKRG-ILKGIVNKECEPIVATGAILGGIPLVDKID
D3S7M2_METSF      SLKGKIFVFPYGKGSTVGSYVIYGLAKKG-ILKGIVNKECEPIVATGAILGGIPLVDKID
C7P5U0_METFA      SLKGKIFVFPYGKGSTVGSYVIYGLAKRG-ILKGIVNKECEPIVATGAILGGIPLVDKVD
C9RI90_METVM      SIKDKIFVFPYGKGSTVGSYVIYGLAKRG-ILKGIINKECETIVATGAILGGIPLVDMVD
D5VQM1_METIM      SLKGKIFAFPYGKGSTVGSYVIYDLAKRG-ILKGIINKECEPIVATGAILGGIPLIDRID
A4FXT5_METM5      SIANKIFVFPTGKGSTVGSYVIYGLAKRG-LLKGMVNFESEPIVATGAILGKIPLVDKVN
A9AB42_METM6      SIANKIFVFPTGKGSTVGSYVIYGLAKRG-LLKGMVNFESEPIVATGAILGKIPLVDKVN
A6VFJ3_METM7      SIANKIFVFPTGKGSTVGSYVIYGLAKRG-LLKGMVNFESEPIVATGAILGKIPLVDKVN
Q6LYT5_METMP      SIANKIFVFPSGKGSTVGSYVIYGLAKRG-LLKGMVNFESEPIVATGAILGKIPLVDKVN
A6UN62_METVS      SIVGKIFVFPTGKGSTVGSYVIYALSKQG-ILKGMINSESEPIVATGAILGKIPLVDKVN
D7DTY0_METV3      SIANKIFVFPTGKGSTVGSYVIYGLAKKG-LLKGIVNQDCEPIVATGAILGKIPLVDHID
A6UU66_META3      TVKNKIFVFPTGKGSTVGSYVIYGLAKNN-ILKGIINADCEPIVATGAILGKIPMVDKID
D3S160_FERPA      SVANKVLVFPSGKGSTVGTYVLLQLKKNGVAPLAIINEKTEVIIAVGAIIAEIPLVDMPE
D2RHH9_ARCPA      RIANKIFIFPHGRGSTVGTYVLLRMKKKGTAPKAIINIETEPIIAVGAIIAEIPLMDKLE
PMDHS_ARCFU       SVAGRILVFPGGKGSTVGSYVLLNLRKNGVAPKAIINKKTETIIAVGAAMAEIPLVEVRD
PMDHS_METTH       SIRGKVLLIPGGKGSTVGSYVIFQMAKNETAPAAIICLNAEPIIATGAIMAGIPMVDRPS
D9PU24_METTM      SMSGKVLVIPGGKGSTVGSYVIFQMSKNGTAPAAIICSNAEPIIATGAIMAGIPMVDRPE
F0T6M3_METLA      NIKNKILVMPSGKGSTVGSYVLYQMAKNSTAPLAVVAIEGEPIIATGAIMAGIPMVDRPE
D3DZ99_METRM      SIKDKILFIPGGKGSTVGSYVIFQMMKNNTAPKAIICLKAEPIIATGAIMSDIPMVDSP-
A5UMD2_METS3      SIKDKVLFIPGGKGSTVGSYVIFQMKKNNTAPKAIICLNAEPIIATGAIMSDIPMVDSP-
Q2NHJ1_METST      CITDKILVIPSGKGSTVGSYVIYQMAKNNTAPRAIICQKAEPIIAIGAIISKIPMVDNPD
E3GYB3_METFV      SIKNKILIIPGGKGSTVGSYVLYQLAKNKTAPAGIICIKAEPIVAVGAIIAKIPLVDGIT
A7I8B4_METB6      SVAGTVLVFPYGKGSTVGSYVIYALSRNGHAPAAIVNTEAEPIIATGAIIGNIPMIDRPK
A3CV39_METMJ      SIAGRVLAFPYGKGSTVGSYVIYALKQNGLAPAAIINTETEPIIAVGAIIAEIPMIDRLP
Q2FUD8_METHJ      DITGSVLAFEYGKGSTVGSYILYALSRNGHAPAAIINQEAETIIVVGAIMGKIPMIDRIK
E1RJU7_METP4      SIGGKVLAFPHGKGSTVGSYIIYALRRNGKAPSAIINIEAETIIAVGAIIADIPMVDKPE
B8GKJ6_METPE      SIEGTIFAFPHGKGSTVGSYILYALARNHKAPAAIINQEAEPIIVVGAIISGIPMVDRLD
A2SRL5_METLZ      SVAGKVLVFPYGKGSTVGSYVLYALAKNHVAPAAIINTECETIIATGAIIAEIPTVDRLK
C7NT80_HALUD      NIAGKVLVFPRGKGSTVGSYVLYGLANNDCAPAAIVNEETETIVATGAILGEIPCLDSPD
PMDHS_AERPE       PLAGRVAAIRRSRGSTVGSYVIYALKENGVAPLAILMERAEPIVIAGCVLAGIPLYDGLP
D9PZT3_ACIS3      SVASRVIVARRPRGSTVGSYVIYALKANGAAPAAIVMSRVDPIIVAGCVLAGIPLVDSIP
PMDHS_METKA       KLTGRVLVLPGGRGSTVGSYVLMEMADRGTAPAGIVVREAEPILVVGCVLGDIPLFHRPE
                   : . :      :*****:*::  :  .     .::    : *:  *. :. **      

PMDHS_METAC       KSPYESLKDGDVVQVNGSEGYIELIKPKGSKIEE---
PMDHS_METMA       KDPYEFLKDGDTVLVNGSEGYIELLKQGEGQAKK---
Q46EJ6_METBF      KNPYEVLNNGDLVLVNGSKGYIELFKQETIKTENEKK
D5E7X8_METMS      SNPFEMLKDGMNVNVDGKEGWLEIKD-----------
PMDHS_METBU       KDPFTIFKNGDRVKVDSTSGFVELMDR----------
D7EBP1_METEZ      RDPYTLLKNGYRVKVDGSNGFIEIKDYNHQN------
PMDHS_METAR       QNPVETIKDGDTVTVDGTAGIIELS------------
D1Z109_METPS      KDPVEIIRDGMTVTVDGTTGTVELPC-----------
PMDHS_METTP       EWILDV-KDGTRVVVDARREVVVLPDGSVKV------
PMDHS_PYRAB       I---SKLRTGMKVRINPRTGEVEIIG-----------
PMDHS_PYRHO       I---SKLKTGMRVRINPQEGEVEILAEGNL-------
PMDHS_PYRFU       I---SKLKSGMKVRVDGERGEVEIIAQGDL-------
PMDHS_THEGJ       V---SKLKTGQRVRINADEGEVEVLDG----------
PMDHS_THEON       V---SKLKSGQRVRVKADEGLVEVEE-----------
PMDHS_THEKO       V---SKLKTGMKVRVDADSGEVEILEDGE--------
PMDHS_THESM       T---SKIRSGQIIEVDADKGEVNVEE-----------
F0LM22_THEBM      I---RKIKNGQIIEVDADRGEIIIHEEEGI-------
PMDHS_METJA       I---EEIKTGDRIVVDGNTGVVKILNK----------
D3S7M2_METSF      I---EKIKTGDRIVVDGNTGVVKILNK----------
C7P5U0_METFA      I---EKINTGDKIIVDGNKGVVKILNK----------
C9RI90_METVM      I---EKIKTGDKILIDGDKGIVKILNKSKN-------
D5VQM1_METIM      I---DKLESGKRIVLDAYKGLVKL-------------
A4FXT5_METM5      I---DEIKDGDIVVVDGNTGTVKIKEQ----------
A9AB42_METM6      I---DEIKDGDIVVVDGNTGTVKIKEQ----------
A6VFJ3_METM7      I---DEIKDGDIVVVDGNTGTVKIKEQ----------
Q6LYT5_METMP      I---DEIKDGDIVVVDGNTGTVKIKEQ----------
A6UN62_METVS      I---DEIKDGDIVVVDGNTGTVKIKQSN---------
D7DTY0_METV3      I---SKLKNGDKIVVDGNNGMVKIEN-----------
A6UU66_META3      I---SEIKTGDKIIIDGNNGTIKIFKK----------
D3S160_FERPA      VNVFEILKSGDIVTVNATEGWIEIE------------
D2RHH9_ARCPA      INPLEVFESGDFAVVNAYEGYVEKRD-----------
PMDHS_ARCFU       EKFFEAVKTGDRVVVNADEGYVELIE-----------
PMDHS_METTH       EDLLGLLEDSMEVEVDADEGKIRF-------------
D9PU24_METTM      ADLFQILEDSLEVEVDAVEGKIRV-------------
F0T6M3_METLA      IDIFDLLHDGQVVEVNADEGYLKII------------
D3DZ99_METRM      -SSVEELVNGQMVEVDSDNGKIEIL------------
A5UMD2_METS3      -EDTDELKNGVLVEVDGDNGKIAIL------------
Q2NHJ1_METST      VDIINTINTNDEITVDADNSTIVIN------------
E3GYB3_METFV      IEDMEKLSKCHEVEIK--NGKIKMIKK----------
A7I8B4_METB6      I-PLDRLMTGTQAIVDGDAGTLEYDGTPV--------
A3CV39_METMJ      P-EFSDLPPGTTVTVNGDTGEVSCDGTS---------
Q2FUD8_METHJ      T-PLTSLPSGTIVEVDGTAGTLTIPDEKVNQV-----
E1RJU7_METP4      K-PISEIPDGSVVTVNGDTGEIIVE------------
B8GKJ6_METPE      I-PFEELKEHRSATVNGETGEVTFDD-----------
A2SRL5_METLZ      ----GDLPKDGIVTVDGTSGTVSFAQCG---------
C7NT80_HALUD      A-DLETLEDGERVAVDADAGTIRRV------------
PMDHS_AERPE       PEFFERVRDGYRVRVHS-DGLVEVLGPGQP-------
D9PZT3_ACIS3      EDQLSKVRDGDLVELDG-SGVVRVRRAAP--------
PMDHS_METKA       RDLVEELSTGDVVKLLP-GGKVEV-------------
                                :      :