CLUSTAL format seed alignment for MF_00079
_____________________________________________________________________________
Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
HIS1_BUCAI -------------MFENNRVRIAMQKTGRLSKDSIRLLTSCGVKINLKQ--QKLIAFAEN
HIS1_BUCAP -------------MFNTNRVRIAMQKTGRLSSESIKLLTCCGIKINLKQ--QKLIAFAEN
HIS1_BUCBP -------------MISNNRLRIAMQKTGRLSDDSKDLLTRCGIKINLHK--QKLIAFAEN
HIS1_ECOLI -------------MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHT--QRLIAMAEN
HIS1_SHIFL -------------MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHT--QRLIAMAEN
HIS1_ECO57 -------------MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHT--QRLIAMAEN
HIS1_SALTI -------------MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHT--QRLIAMAEN
HIS1_SALTY -------------MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHT--QRLIAMAEN
HIS1_YERPE -------------MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQ--QRLIAFAEN
HIS1_PHOLL -------------MLDKSRLRIAMQKSGRLSEDSQELLARCGIKINLQQ--QRLIAFAEN
HIS1_BLOFL -------------MLDKSRLRIAMQKSGRLSKESQKLLEQCGIKINLQQ--QQLLAFAEN
HIS1_HAEIN ---------MTNTTMQPNRLRIALQKKGRLSQDCAILLKQCGVKINWNE--QRLIAYAEN
HIS1_PASMU -------------MIESKRLRIAMQKSGRLSQESQALLKQCGVKINLQE--QRLIAYAEN
HIS1_CAMJE -------------MQENTRLRIAIQKSGRLSKESIELLSECGVKMHIHE--QSLIAFSTN
HIS1_SHEON -------------MTESNRLRIAIQKSGRLSTDSQQLLKSCGVKFSINE--QRLIAHADN
HIS1_VIBVU --------------MQTQRLRIAIQKKGRLSEECQGLLKKCGVKFNIMG--ERLVVHSEN
HIS1_VIBVY --------------MQTQRLRIAIQKKGRLSEECQGLLKKCGVKFNIMG--ERLVVHSEN
HIS1_VIBPA --------------MQTQRLRIAIQKKGRLSKESQALLKQCGVKFNVMG--ERLVVHSEN
HIS1_VIBCH --------------MQTQRLRIAIQKKGRLSQECQELLKKCGVKFNIMG--ERLVVHSLN
HIS1_XANAC -------MSASTAAPARDRLRIAIQKSGRLAEPARSLLAACGLSWRQSR--DKLFCYGES
HIS1_XANCP -------MSASTAAPARDRLRIAIQKNGRLAEPARSLLAACGLSWRQSR--DKLFCYGES
HIS1_XYLFA -------MSASTALPVRDRLRIAIQKSGRLTEPARRLLTACGLSWRQSR--DKLFCYGES
HIS1_XYLFT -------MSASTALPVRDRLRIAIQKSGRLTEPARRLLTACGLSWRQSR--DKLFCYGES
HIS1_BACTN ------------------MLRIAVQAKGRLFEETMALLGESDIKISTTK--RTLLVQSSN
HIS1_CORGL ------------------MLKIAVPNKGSLSERAMEILAEAGYAGRGDS--KSLNVFDEA
HIS1_COREF ------------------MLKIAVPNKGSLSERAMEILNEAGYAGRGDS--KSLNVLDSA
HIS1_CORDI ------------------MLKIAIPNKGSLSEAAVEILAEAGYAGRGES--KTLNVYDKT
HIS1_MYCLE ------------------MLRVAVPNKGALSEPATEILAEAGYRRRTDP--KDLTVVDPV
HIS1_MYCTU ------------------MLRVAVPNKGALSEPATEILAEAGYRRRTDS--KDLTVIDPV
HIS1_MYCPA ------------------MLRVAVPNKGTLSEPATEILAEAGYRRRTDS--KDLTVIDPV
HIS1_STRAW ------------------MLRIAVPNKGSLSGPAAEMLHEAGYQQRRES--KELRIVDPE
HIS1_STRCO ------------------MLRIAVPNKGSLSGPAGEMLHEAGYQQRRES--KELRIVDPV
HIS1_BIFLO ------------------MLRIAVPNKGMLSEPAWNMLAEAGYRLRTNP--RQLVVQDPD
HIS1_RHOBA MVPMTTLAPLGSGSDPDSFLRLGIPSKGRLSELATGLLNQAGLSFRRQN--RGLFARVSG
HIS1_METAC ------------------MIRIAIPNKGRLHEPTMSLFKDAGLPISGGAESRILFAKTTD
HIS1_METMA ------------------MIRIAIPNKGRLYEPTISIFKDAGLPISGGAESRKLFAKTTD
HIS1_HALSA -------------------MRIAVPNKGRLHDPTLALLDRAGIGVEDGAD-RQLYADTVD
HIS1_METKA ------------------MITVAVPNKGRLHEPALKLLERAGIGVEEPLG-RRLKARTTD
HIS1_METJA ------------------MIMFALPNKGRISEPVMKVLEKAGLKITVK--GRSLFANTVD
HIS1_METMP ------------------MILLALPNKGRISKPVNEILEKSGLKISVH--GRSLFAKTVD
HIS1_METTH -----------------MKIRIAVPSKGRISEPAIRLLENAGVGLKDTV-NRKLFSKTQH
HIS1_SACS2 ---------------MVRNLKIAIPNKGRLQQPTLQFLQSVGIKPLASD-DRALIVPTSW
HIS1_SULTO -------------------MKMAIPNKGRLKDPVVQFLASVGVKGNFSD-DRALIIPTNW
HIS1_PYRAE -------------------MLLAVPSKGRLQEPTLKLLEAVGIRPLASD-ERALVVPTSW
HIS1_CHLTE -------------MSNNKVLKLGLP-KGSLQDSTLELFANAGFHFSVQS--RSYFPSIDD
HIS11_GEOSL -------------MSG--LLNFGVP-KGSLENATVELFRKAGWQISISS--RSYFPGVDD
HIS1_BRADU ---------------MSAPFVLAVPSKGRLQENTEAFFARAGLKLSKAGGARDYRGTIAG
HIS1_RHOPA ---------------MSAPFVLAVPSKGRLQENAEAFFARAGLTLSKPGGARDYRGTIAG
HIS1_CAUVC ---------------MSTPMIFAIPSKGRLKDQVEAWLADCGFKLEMTGGARGYSAELSG
..: .* : : .
HIS1_BUCAI MP-IDVMLVRDDDIPGLVMDGVVDLGIVGENVLEEELLKRKSQKSECSYITLRRLDFGVC
HIS1_BUCAP MP-IDVMLVRDDDIPGLVMDGVVDLGIVGENVLQEELLHRISQNLENSYITLRRLDFGIC
HIS1_BUCBP MP-IDVMCVRDDDIPGLVMDKVVDIGIIGENVLEEEVLNRQVQLDNCSYTKLKRLDFGIC
HIS1_ECOLI MP-IDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGC
HIS1_SHIFL MP-IDILRVRDDDIPCLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGC
HIS1_ECO57 MP-IDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGC
HIS1_SALTI MP-IDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYLTLRRLDFGGC
HIS1_SALTY MP-IDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYLTLRRLDFGGC
HIS1_YERPE MP-IDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGC
HIS1_PHOLL MP-IDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLSRRAQGENPRYFTLRRLDFGTC
HIS1_BLOFL MT-IDIMRVRDDDIPGLIMDGVVDLGIIGENVLEEALLTRQSQGDNPCYVTLRRLDFGDC
HIS1_HAEIN LP-IEILRVRDDDIPGLIFDGVVDLGIIGENVLEEEELGRRAANETVTYKKLRQLDFGDC
HIS1_PASMU MP-IDILRVRDDDIPGLVFDGVVDLGIIGENVLEEEELTRQAAGETVNYKKLRRLDFGGC
HIS1_CAMJE LP-IDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYC
HIS1_SHEON MP-IDLLRVRDDDIPGLVMDGVVDLGIIGENVLEEEQIERQTLNKPAEYVKLRQLDFGAC
HIS1_VIBVU MP-IDLLLVRDDDIPGLIMDGVVDLGFIGENVLEEVRLERKATGDACQFETLSRLDFGGC
HIS1_VIBVY MP-IDLLLVRDDDIPGLIMDGVVDLGFIGENVLEEVRLERKATGDACQFETLSRLDFGGC
HIS1_VIBPA MP-IDLLLVRDDDIPGLIMDGVVDLGFIGENELEEVRLDRKALGEPCEFVQLRRLDFGGC
HIS1_VIBCH MP-IDLLLVRDDDIPGLIMDGVVDLGFVGENVLEETRLDRLALNQRNEFTTLRRMDFGGC
HIS1_XANAC LP-VDLLLVRDDDIPGLIADGVCDLGIVGQNELEEQAAERRRHGLPAAYHAVRGVGFGQC
HIS1_XANCP LP-VDLLLVRDDDIPGLIADGVCDLGIVGQNELDEQASARRRAGLPAAYHAVRGVGFGQC
HIS1_XYLFA LP-VDLLLVRDDDIPGLIAQGVCDLGIVGRNELDEQAASRRRNGLPVPYQTLRGLHFGQC
HIS1_XYLFT LP-VDLLLVRDDDIPGLIAQGVCDLGIVGRNELDEQAASRRRNGLPVPYQTLRGLHFGQC
HIS1_BACTN FP-IEVLFLRDDDIPQTVATGVADLGIVGENEFMEKEED---------AEIIKRLGFSKC
HIS1_CORGL NN-VEFFFLRPKDIAIYVAGGQLDLGITGRDLARD---------SQADVHEVLSLGFGSS
HIS1_COREF ND-VEFFYLRPKDIAIYVAGGQLDLGITGRDLAAD---------SRADVHEVLSLGFGSS
HIS1_CORDI ND-VEFFFLRPKDIAIYVAGGQLDLGITGRDLATD---------SHANVEEVMSLGFGNS
HIS1_MYCLE NR-VEFFFLRPKDIAIYVGSGDLDFGITGRDLVHD---------SDASVCERLALGFGSS
HIS1_MYCTU NN-VEFFFLRPKDIAIYVGSGELDFGITGRDLVCD---------SGAQVRERLALGFGSS
HIS1_MYCPA NQ-VEFFFLRPKDIAIYVGSGELDFGITGRDLVGD---------SDAPVRERLALGFGSS
HIS1_STRAW NE-VEFFYLRPRDIAIYVSSGRLDIGLTGRDLLID---------SGANAEEILPLGFARS
HIS1_STRCO NE-VEFFYLRPRDIAIYVSSGKLDIGITGRDLLVD---------SGAHAEEILPLGFARS
HIS1_BIFLO NG-IELFYLRPLDIAVYVGRGAIDVGITGQDLLKN---------SGTAALEHMPLGFGTS
HIS1_RHOBA LP-IDLIFLRTDDIPTLCAEGAIDMGITGSDLIEE---------AGANVEQRMAFGVGRC
HIS1_METAC PD-IHILFARAADIPEYVQDGAADVGVTGMDLITER-------GAD--VEALLDLKYGKA
HIS1_METMA PD-IHILFARAADIPEYVQDGAADVGITGMDLITER-------GAN--VEALLDLKFGRA
HIS1_HALSA PA-LTVLYARAADIPEYVADGAADAGITGHDQLRES-------DVDC-VEERLDLNYGSC
HIS1_METKA PD-IEVMFVRAADIPRLVEEGVAQLGITGYDLIVEA-------GAE--VKELLDLRFGRA
HIS1_METJA DN-IKVMFARARDIPEFVADGVADIGVTGYDLVLER-------NVEDKVDFLLDFGFGFA
HIS1_METMP PE-IKVMFARAKDIPEFVRDGVADVGVTGYDLMLER-------DTEEELEMLLDFKFGNA
HIS1_METTH PQ-IEVMFSRAADIPEFVADGAADLGITGYDLIVER-------GSD--VEILEDLKYGRA
HIS1_SACS2 EG-VQLVMIRTEDIPNIVETGATELGITGHDYVIES-------SAD--VEELIKLDFGRS
HIS1_SULTO EG-VQLVMVRTEDIPSIVESGAAELGITGHDYVIES-------NSD--VDELIRLDFGKS
HIS1_PYRAE SD-VNLIRARPEDIPYLVESGRVWAGITGHDYVVES-------GSN--VAEVLELEFGRG
HIS1_CHLTE DE-LEAILIRAQEMGRYVSLGAFDAGLTGKDWIIETDAD----VVEVADLVYSKASMRPV
HIS11_GEOSL DE-MNCKLIRPQEMGKYVERGTIDAGIAGRDWVRENESD----VVEVCEMVYSKVSRRPA
HIS1_BRADU LDNVEVAYLSASEIAAQLSRGLAHLGVTGEDLVRENIA-----DADKRVSLIEGLGFGYA
HIS1_RHOPA LDNVEVAYLSASEIAANLARGSVHFGVTGEDLVRESIT-----DADKRVLLIDGLGFGYA
HIS1_CAUVC LPGVSVRLLSAGDIAAGLDSGDLHLGVTGEDLLRERGD-----DMDSRVMLLRALGFGRA
: :: *. * : :
HIS1_BUCAI RLSLALPV-----------NTIYTNITCLK--NIRIATSYPHLLKKYLDEKN-ISFKSCM
HIS1_BUCAP RLSLAIPI-----------NTPYVDITSLK--NFRIATSYPHLLKKYLDSKN-IVFKSCM
HIS1_BUCBP RLSLAVPI-----------NIEYNNIHCLN--HTRIATSYPHLLKRYCDKKK-LTFKSCM
HIS1_ECOLI RLSLATPV-----------DEAWDGPLSLN--GKRIATSYPHLLKRYLDQKG-ISFKSCL
HIS1_SHIFL RLSLATPV-----------DEAWDGPLSLN--GKRIATSYPHLLKRYLDQKG-ISFKSCL
HIS1_ECO57 RLSLATPV-----------DDAWDGPLSLN--GKRIATSYPHLLKRYLDQKG-ISFKSCL
HIS1_SALTI RLSLATPV-----------DEAWDGPAALD--GKRIATSYPHLLKRYLDQKG-VSFKSCL
HIS1_SALTY RLSLATPV-----------DEAWDGPAALD--GKRIATSYPHLLKRYLDQKG-VSFKSCL
HIS1_YERPE RLSLAAPL-----------DAEYTGPQCLQ--DTRIATSYPHILKQYLDKQG-VRFKSCL
HIS1_PHOLL HLSLAAPL-----------DYNYTGVECLQ--NARIATSYPHLLKRYLDQKK-ILFKSCL
HIS1_BLOFL RLSMALPM-----------DKPWNGPKCLQ--GKRIATSYPHLLKQYLDKLG-INFKSCL
HIS1_HAEIN RLSLAVDR-----------DCHYENVKDLA--NRRIATSYPHLLKRYMNENG-VSFKSCL
HIS1_PASMU RLSIAIPQ-----------DEAYNGISDLK--NARIATSYPNLLKRYMQQQG-VDFKTCS
HIS1_CAMJE RLSLALPQ-----------ENKFQNLKDFE--GLRIATSYPQLLKRFMKENG-INYKNCT
HIS1_SHEON RLSLAVPT-----------EFSYADASSLE--GLRIATSYPNLLRRFMQQKS-INYRDCM
HIS1_VIBVU RLSIAIDK-----------DEKYNGPQDLA--GKRIATTYPQLLKAYMDRQG-VPFSTCM
HIS1_VIBVY RLSIAIDK-----------DEKYNGPQDLA--GKRIATTYPQLLKAYMDRQG-VPFSTCM
HIS1_VIBPA RLSIAIDK-----------DEEYNGPQDLA--GKRIATTYPQLLKAYMDEAG-VPFSTCM
HIS1_VIBCH RLSIAIEK-----------DAEYRGPQDLN--GKRIATTYPQLLKAYMDRQG-VDFSTCM
HIS1_XANAC RLMLAVPE-----------EWDWHGVAQLA--GKRIATSYPAILADWLERQG-IEATVVE
HIS1_XANCP RLMLAVPE-----------EWGWQGVAQLA--GKRIATSYPAILADWLERQG-IDASVVE
HIS1_XYLFA RLMLAVPE-----------EWEWQDISQLT--GKRIATSYPAILTDWLQTHH-IAAQIVE
HIS1_XYLFT RLMLAVPE-----------EWEWQDISQLT--GKRIATSYPAILADWLQTHH-IAAQIVE
HIS1_BACTN RLSLAMPK-----------DIEYPGLSWFN--GKKIATSYPVILRNFLKKNG-VNAEIHV
HIS1_CORGL TFRYAAP------------ADEEWSIEKLD--GKRIATSYPNLVRDDLAARG-LSAEVLR
HIS1_COREF TFRYAAP------------AGQGWSIEKLE--GKRIATSYPNLVRDDLAARG-ITAEVIR
HIS1_CORDI SFRYAAP------------ADQKWTVEMLE--GKRIATSYPNLVRDDLQARG-INATVIR
HIS1_MYCLE SFRYAGP------------AGRDWTTSDLA--GKRIATAYSNLVRKDLVAKG-IEATVIR
HIS1_MYCTU SFRYAAP------------AGRNWTTADLA--GMRIATAYPNLVRKDLATKG-IEATVIR
HIS1_MYCPA SFRYAGP------------AGRDWKIADLA--GKRIATAYPNLVRKDLAERG-IEATVIR
HIS1_STRAW TFRFAGK------------PGTAKGIEDLA--GLTVATSYEGIVAKHLADSG-IDASVVH
HIS1_STRCO TFRFAGK------------PGAATGIDDLK--GRTVATSYEGIVAAHLADRG-VDASVVH
HIS1_BIFLO TFRFAAPN-----------ESPITTLEDIQ--GKRVATTFDKLVHDYLVEHG-IQAETIH
HIS1_RHOBA RLAFCVPD-----------DEDYTDAAQLN--GKRIATSFPHVTEQYLATKN-AKAHLVS
HIS1_METAC SLVLAVPE-----------ESVFQSARDLE--GKKVATEFPEITRQYFKNLG-ITVEVIT
HIS1_METMA NLVLAVPE-----------DSDFEKAQDLE--GKKVATEFPEITRRYFEKLG-VNVNVIK
HIS1_HALSA RLVLAAPE-----------DGDVTAPADLD--GATVATEFPTITRAYFADTT-ATPEIVE
HIS1_METKA RLVLAVPE-----------ESDVKSPEDLD--GGTVATEFPNIARQYFEDVG-VDVEIIQ
HIS1_METJA KLVLAAPE-----------SSNINSIDDIKE-GMRVATEFPNLTKKYFEKLN-KKVEIIE
HIS1_METMP RLVLAAPE-----------NSDVNSIEDVKN-GMKIATEFPGLTKRYLEKKG-LNLEIIE
HIS1_METTH SLVLAAPE-----------DSTIRGPEDIPR-GAVIATEFPGITENYLREHG-IDAEVVE
HIS1_SACS2 KIVLAVPQ-----------TWRENSVDELKGKEFRVATKYYNIAKEYVRRRE-LNAKVVK
HIS1_SULTO KIVLAVPV-----------SWNIDRVEEIK-DEIRIATKYYNIAKQYLEKKN-IKAKIVK
HIS1_PYRAE KLVVAVPR-----------SSGITSVEDLP-PGARIATKFVNIAYNYFAELG-KRVRIIR
HIS1_CHLTE RWVLAVPE-----------SSPIKTVKDLE--GKHIATEVVNITKKYLAENG-VNASVEF
HIS11_GEOSL RWVLVVTR-----------DSAVQKPEDLH--GATISTELVGFTKRYFAERN-IPVTVEF
HIS1_BRADU DVVVAVPQAWIDVRTMADLDDVTTGFREQHHMRMRVATKFVNLTRAFFQNHGITDYRIVE
HIS1_RHOPA NVVVAVPQAWIDVRTMADLDDVTTGFRAQHNRRMRVATKYINLTRGFFAQHSVVDYRIVE
HIS1_CAUVC DLVVTAPKNWLDVDTMADVDEVGHAHLARTGRRLRVATKYVTQTRAFFARHGVADYRIVE
::*
HIS1_BUCAI LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVQV--VYHSHACLICKTGNINS----
HIS1_BUCAP LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVQV--VFRSHACLICKTGNINF----
HIS1_BUCBP LNGSVEVAPRAGLSDAICDLVSTGATLEANGLREVEV--IFFSKACVICKTGFISL----
HIS1_ECOLI LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEV--IYRSKACLIQRDGEMEE----
HIS1_SHIFL LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEV--IYRSKACLIQRDGEMEE----
HIS1_ECO57 LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEV--IYRSKACLIQRDGEMEE----
HIS1_SALTI LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEV--IYRSKACLIQRDGEMAQ----
HIS1_SALTY LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEV--IYRSKACLIQRDGEMAQ----
HIS1_YERPE LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEV--IYRSKACLIQRDGEMSV----
HIS1_PHOLL LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEI--IYRSKACLIQRDGEMPA----
HIS1_BLOFL LNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEV--IYRSKACLIQRSGNLSK----
HIS1_HAEIN LNGSVEVAPSAGIAYAICDLVSSGATLEANGLKEVDV--IYRSKACLIQRAEPLES----
HIS1_PASMU LTGSVEVAPRAGLADAICDLVSSGATLEANGLKEVEI--IYRSKSCLIQRAAELSP----
HIS1_CAMJE LTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKV--IYESRACLIQKENALSK----
HIS1_SHEON LKGSVEVAPRAGLADGICDLVSTGATLEANGLYETEV--IYRSMACIIQSTQTQAP----
HIS1_VIBVU LTGSVEVAPRAGLADAIADLVSTGATLEANGLKEAEV--IFQSKATLIQRSGEFAQ----
HIS1_VIBVY LTGSVEVAPRAGLADAIADLVSTGATLEANGLKEAEV--IFQSKATLIQRSGEFAQ----
HIS1_VIBPA LTGSVEVAPRAGLADAIADLVSTGATLEANGLKEAEV--IFRSKATLIQRIGEFDA----
HIS1_VIBCH LTGSVEVAPRAGLADAIADLVSTGATLEANGLKEVEV--IFESKATLIQRPGAFAA----
HIS1_XANAC LSGSVEIAPRLGTADLICDLVSSGATLAANQLKPVEL--VMESEAVLAGAVREPAD----
HIS1_XANCP LSGSVEIAPRLGTADLICDLVSSGATLAANQLKPVEL--VMESEAVLAGAVREPAD----
HIS1_XYLFA LSGSVEIAPRLGTADLICDLVSSGATLAAHQLKPVIQ--IMESQAVLAGMIRQPAD----
HIS1_XYLFT LSGSVEIAPRLGTADLICDLVSSGATLAAHQLKPVIQ--IMESQAVLAGMICQPAD----
HIS1_BACTN ITGSVEVSPGIGLADAIFDIVSSGSTLVSNRLKEVEV--VMKSEALLIGN-KNMSD----
HIS1_CORGL LDGAVEVSIKLGVADAIADVVSTGRTLRQQGLAPFGE--VLCTSEAVIVGRKDE------
HIS1_COREF LDGAVEISIKLGVADAIADVVSTGRTLRQQGLEPFGE--SLCTSEAVIVGRRDE------
HIS1_CORDI LDGAVEISIKLGVADAIADVVSTGRTLRKQGLATFGE--VICQSEAVIVGQQGN------
HIS1_MYCLE LDGAVEISVQLGVADVIADVVGSGRTLSLHDLVAFGE--PLCDSEAVLIERGDRGSLDHH
HIS1_MYCTU LDGAVEISVQLGVADAIADVVGSGRTLSQHDLVAFGE--PLCDSEAVLIERAGT---DGQ
HIS1_MYCPA LDGAVEISVQLGVADAIADVVGSGRTLSLHNLVAFGE--PLCDSEAVLIE-SDRG--GQD
HIS1_STRAW LDGAVETAIELGVAEVIADVVETGTSLRNAGLEVFGE--PIMKSEAVVIRRVGAG--TDE
HIS1_STRCO LDGAVETAIELGVAEVIADVVETGTSLRNAGLEVFGE--PIMKSEAVVIRRSDAE--PDE
HIS1_BIFLO LDGAVESSVQLGVADLIADVVSTGTTLRNAGLRVFAE--PLMHSEACLIRSPRLN-----
HIS1_RHOBA LSGSVEAMIRLGVADAIVDLVETGSTLAANRLRILEE--IGHYETVLIQNGTHRC-----
HIS1_METAC VSGACEMTPHVGIADAIVDISSSGTTLLINHLKAIDT--VFSSTVHLIANKKSLKE----
HIS1_METMA VSGACEMTPHVGIADAIVDISSSGTTLLINHLKAIDM--AFSSTVYLIANKESLRT----
HIS1_HALSA VTGATELTPHVEMADAIVDITSTGTTLRVNRLQVVDE--VLSSSVRLFAH-EDVHD----
HIS1_METKA VSGATEIMPRIGVADAIVDLCSTGTTLKVNRLRVVDE--LLETSARLIAN-PDATD----
HIS1_METJA LSGATEIAPFIGIADLISDLTSTGTTLRLNRLKVIDE--IVSSTTRLIANKNSLKDK---
HIS1_METMP LSGATEIAPFIGVSDLICDLTSTGTTLQLNRLKEIEN--VVSSSTRLVANKKSMEDP---
HIS1_METTH LTGSTEIAPFIGVADLITDLSSTGTTLRMNHLRVIDT--ILESSVKLIANRESYAT----
HIS1_SACS2 ISGAAEVMPSLGAAEAIIDVMSTGTTLKLHGLKAIDV--IMDSYAVVIGNRNWIKN----
HIS1_SULTO ISGAAEVMPSLGAADAIIDVMSTGTTLKLHGLKPLDT--ILESSAVVIANRNWVKS----
HIS1_PYRAE VTGSVEVLPQLGIADAILDVMATGTTLEVHGLVPIAT--VLETSARLVVNPQYV------
HIS1_CHLTE SWGATEVKPPE-LADAIVEVTETGSSLRANKLRIVET--VLQSNTQLIANKAAWAD---P
HIS11_GEOSL SWGATEAKVVDGLCDAIVEVTETGSTIKANGLRIVCD--LMESVPVLIANKAAWAD---P
HIS1_BRADU SAGATEGAPAAGSAELIVDITTTGATLAANGLRVLDDGMILRSQANLVASRDADWS---P
HIS1_RHOPA SAGATEGAPAVGTAEMIVDITTTGATLAANGLKVLDDGVLLRSQANLVASREADWS---D
HIS1_CAUVC SSGATEGAPAAGAAELVVDITTTGATLAANGLKILSDGVILKSQAQLTASLTAGWN---G
*: * . : :: :* :: *
HIS1_BUCAI IKKEFINKLMTRIKGVIKARESKYIMLHAPIKQLEAVISLLHGAERPTILKLAGDD----
HIS1_BUCAP AKKEVINKLMTRIKGVIKARESKYIMLHAPVNKLEEVISLLHGAEKPTILKLAGDD----
HIS1_BUCBP EKKNVIDKLMTRIQGVIKARESKYIMLHAPIEKLEKVMNLLHGAENPTILKLAGDN----
HIS1_ECOLI SKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQ----
HIS1_SHIFL SKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQ----
HIS1_ECO57 SKQQLIDKLLTRIQGVIQARESKYIMMHAPTQRLDEVIALLPGAERPTILPLAGDQ----
HIS1_SALTI SKQQLIDKLLTRIQGVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQ----
HIS1_SALTY SKQELIDKLLTRIQGVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQ----
HIS1_YERPE DKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDK----
HIS1_PHOLL DKQQLIEKLLTRIQGVIQARESKYIMLHAPSAKLEEVIALLPGAERPTILPLVGDQ----
HIS1_BLOFL TKQSLIDKLMIRIQGVIQARESKYIMLHAPAERLEEIINLLPGAESPTVLPLAGNQ----
HIS1_HAEIN TKQALVDKLLTRIQGVQQAAESKYIMLHAPKEKLEKITALLPGVENPTILPLASDT----
HIS1_PASMU EKQALVDKLLTRIQGVQQAAESKYIMLHAPKEKLEEITALLPGVENPTILPLAHDN----
HIS1_CAMJE EKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDE----
HIS1_SHEON SKQALIDRILSRVNGVIRARESKYILLHAPTETLDQIVALLPGAENPTVLPLNDDT----
HIS1_VIBVU DKQALIEKLLTRMQGVQQAKESKYIMLHAPVDKLEQIKALLPGAEDPTVLPLSAEK----
HIS1_VIBVY DKQALIEKLLTRMQGVQQAKESKYIMLHAPVDKLEQIKALLPGAEDPTVLPLSAEK----
HIS1_VIBPA DKAELINKLLTRMQGVQQAKESKYIMLHAPAGKLEQIKALLPGAEDPTVLPLSADK----
HIS1_VIBCH DKAALIDKLLTRMHGVQQAKESKYIMLHAPVEKLAQIKTLLPGAEDPTVLPLSADK----
HIS1_XANAC ARAGLLAMLLRRMDGVLKLRDSKLLMFRAEQTKVDALRRLLPDADPLVQLPDDGN-----
HIS1_XANCP ARAALLAMLLRRMDGVLKLRDSKLLMFRAEQGNVDALRRLLPDADPLVQLPDDGN-----
HIS1_XYLFA ARAGLLAMLLRRMDGLLTLRDSNLLMFRAFQEHLDALTHLLPDADPLVQLPDDGS-----
HIS1_XYLFT ARAGLLAMLLRRIDGMVNLRDSNLLMFRAFQEHLDALTRLLPDADPLVQLPDDGS-----
HIS1_BACTN EKKEVLEELLFRMNAVKTAEDKKYVLMNAPKDKLEEIIAVLPGMKSPTIMPLAQE-----
HIS1_CORGL KVTPEQQILLRRIQGILHAQNFLMLDYNVDRDNLDAATAVTPGLSGPTVSPLARD-----
HIS1_COREF EITPAQRVLLSRIQGILHAQNYLMLDYNVDRDRLDEASAVTPGISGPTVSPLARE-----
HIS1_CORDI VVDNEQKVFLRRIEGILHAQNYLMLDYNIDRVNLAASEKITPGISGPTVSPLARE-----
HIS1_MYCLE ETVAARDQLVARVQGVVFGQQYLMLDYDCPRSVLDKATLITSGLESPTIAPLAEP-----
HIS1_MYCTU DQTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAPLADP-----
HIS1_MYCPA DTQAARDQLVARIQGVVFGQQYLMLDYDCPRAVLDKATAITPGLESPTIAPLADA-----
HIS1_STRAW AAESKVQQFLRRLQGVLVARTYVMMDYDCRAEHLEKAVALTPGLESPTISPLHNE-----
HIS1_STRCO TTEPKVQQFLRRLQGVLVARTYVMMDYDCRVEQLEKAVALTPGLESPTVSPLHNE-----
HIS1_BIFLO EQDSRLAVLTRRLQGVLTAHQYVLMDYDIPISKVAAAVAVTPGFESPTISPLHDK-----
HIS1_RHOBA --KEVADRLVSRLEGVVLARDYSLVEYNIPRSRVSEAEKITPGFNSPTINSLEDK-----
HIS1_METAC --KGKILDIKTALESVLNAKKKRYLMMNVPEASLQAVKEVLPGMSGPTVMKVESSRSSEE
HIS1_METMA --KEKILDIKTAFESVLNAKKKRYLMMNVPESSLKAVKEVLPGMSGPTVMKVESSKFSEE
HIS1_HALSA --DPKVQQVETALRSVLDAHGKRYVMLNAPADRLDDVKAVLPGLGGPTVLDVD-----EP
HIS1_METKA --GEVIRRVYLSLKGVLNADGKCLVMMNVPRERLEEFHELLPGVTGPTVSEIYG----DE
HIS1_METJA EKREKINQIVIAIKSVLFAETKRLIMMNAPKDKVEEIRKLIPGMAGPTVSKVLS----DD
HIS1_METMP EKSAKINQVLSGIKSVMYAQSKRLIMMNAPKDKVSEITSVIPGMGGPTVSEILS----NC
HIS1_METTH -KSGIIEELRTGIRGVIDAEGKRLVMLNIDRKNLDRVRALMPGMTGPTVSEVLS----DN
HIS1_SACS2 DEADRINLLLTMMKGAIAAKGKKMIFMNVPDNKLDGVINSLPAMLAPAITRLSR-----S
HIS1_SULTO EEADKINLLLTMMKGALMARNKKMIFMNVPDDKLDKVIASLPAMLSPTLSKLAK-----S
HIS1_PYRAE -EHDLTKKLVTFIKGFYAAQGKKMVFLNVPASRLDAVLAVLPAMEAPSVTKLAK-----G
HIS1_CHLTE WKRKKIENMAMLLQGAINAQGKVGLKMNAPKAALDKIMSGIPALRQPTVSDLADK-----
HIS11_GEOSL WKREKIETIATLLKSALAAEGMVGLKMNAPNDQLEAITRVLPSLKNPTVSHLFNS-----
HIS1_BRADU QARETARVILDHIAARARANKYREVRTRFRQCDAALLGEAHSRFGVEAPFGGPT------
HIS1_RHOPA TARETARVILDHIASRARAGKYKEVRTRFKGCNDALLAEAHSRFGVVSPFGGPT------
HIS1_CAUVC EQLDALRRLLSVVEAKGRAGKLATLVWPAEQDRAAQDAVA----AFIARGGSRR------
. . . :
HIS1_BUCAI NRVAMHMVSSETLFWETMEKLKLLGASSILVLPIEKMME-----------------
HIS1_BUCAP HRVAMHMVSSETLFWETMEKLKSLGASSILVLPIEKMME-----------------
HIS1_BUCBP TRVAMHMVSSETLFWETMEKLKLLGASSILVLPIEKMME-----------------
HIS1_ECOLI QRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME-----------------
HIS1_SHIFL QRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME-----------------
HIS1_ECO57 QRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME-----------------
HIS1_SALTI QRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME-----------------
HIS1_SALTY QRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME-----------------
HIS1_YERPE SRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME-----------------
HIS1_PHOLL NRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME-----------------
HIS1_BLOFL HRVAIYMVSNEALFWETMENLKNLGASSILVLPIEKMME-----------------
HIS1_HAEIN TRVAMHVVSQENLFWETMEQLKEAGASSILVLPIEKMME-----------------
HIS1_PASMU SKVAMHVVSQENLFWETMEQLKDAGASSILVLPIEKMMG-----------------
HIS1_CAMJE KNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK-----------------
HIS1_SHEON NRVAIHAVSTEDLFWDTMEQLTALGASSILVMPIEKMMG-----------------
HIS1_VIBVU QRVAVHLVSTENLFWETMEQLKELGASSILVLPIEKMME-----------------
HIS1_VIBVY QRVAVHLVSTENLFWETMEQLKELGASSILVLPIEKMME-----------------
HIS1_VIBPA QKVAVHLVSTENLFWETMEQLKELGASSILVLPIEKMME-----------------
HIS1_VIBCH SKVAVHMVSSENLFWETMEQLKALGASSILVLPIEKMME-----------------
HIS1_XANAC GALRLQTMCHGAVTWQRLEELERAGAQGLMVLTVERSLA-----------------
HIS1_XANCP GALRLQTMCHGAVTWQRLEELERAGAQGLMVLTVERSLA-----------------
HIS1_XYLFA GTLRVQTMCHGTITWQRLEELERAGAQGLMVLTVERSLA-----------------
HIS1_XYLFT GTLRVQTMCHGTITWQRLEELERAGAQGLMVLTVERSLA-----------------
HIS1_BACTN GWCSVHTVLDEKRFWEIIGKLKGLGAEGILVLPIEKMIV-----------------
HIS1_CORGL NWVAVRAMVPRRSANAIMDKLAGLGAEAILASEIRIARI-----------------
HIS1_COREF NWVAVRAMVPLKSANATMDKLASIGAEAILASEIRIARI-----------------
HIS1_CORDI NWVAVRAMVPRKEANHIMDQLSELGAQAILASEIRIARL-----------------
HIS1_MYCLE GWVAIRALVPRRDINGIMDELAAIGAKAILASDIRFCRF-----------------
HIS1_MYCTU DWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF-----------------
HIS1_MYCPA DWVAIRALVPRRGVNEIMDELAAIGAKAILASDIRFCRF-----------------
HIS1_STRAW GWVAVRAMVPAKEAQRIMDDLYALGARAILTTAIHACRL-----------------
HIS1_STRCO GWVAVRAMVPAKEAQRIMDDLYEIGARAILTTAIHACRL-----------------
HIS1_BIFLO QWNAVRVMVPKAKVNQLMDDLYEVGARGIIVTALQASRM-----------------
HIS1_RHOBA DWCAVQVMVRRGEVVEVMERLKEIGASGIFEMTINNCRL-----------------
HIS1_METAC SFLAVHSVVDADLIFTIVNKLKNVGARDILVVPIERIMP-----------------
HIS1_METMA SILAVHAVVDADLIFTIVNRLKKVGARDVLVVPIERIMP-----------------
HIS1_HALSA GTVAVHAVVPERDVFEAISELKAVGASGILVTEIERLVD-----------------
HIS1_METKA DMVEVYAVVNEEDVSEVVLRAKELGAEGIIVLPIERMIP-----------------
HIS1_METJA NMVAIHAVVNEDEIFTLVPKLHALGARDILVVPIERIL------------------
HIS1_METMP NMLAINAVIDENKVFETVSNLEKLGARDILVVPIERIL------------------
HIS1_METTH GVVAVHAVVDEKEVFNLINRLKAVGARDILVVPIERIIP-----------------
HIS1_SACS2 DIWEVITVAEEDILPEVIAKVKAAGARDIVVIDIEKVVK-----------------
HIS1_SULTO DAWEVITVVDEDLIPEVIAKVKANGARDIVVVNIEKVVK-----------------
HIS1_PYRAE DVYEVFSVVPEDVLPDLVMKLKEAGARDIVITPIEKLIV-----------------
HIS1_CHLTE EWVALEVIVSEKIVRTLIPELKRAGAEGIFEYNINKLID-----------------
HIS11_GEOSL DWVSIESILPEKEVRRIVPELIKLGAEGIVEYPLNKII------------------
HIS1_BRADU SSGMLTLHCPPGQLYALASFLREHGAETVSVVSLDYVFDRENPLFAKLEAFLRR--
HIS1_RHOPA SSGMLTLHCPPAQIYALGSFLRQHGADTVSVAALDYVFDKENPLFSKLAAFLPQ--
HIS1_CAUVC ANGALLATA---DLFDAAAALAEAGVEPVTVSRPDYVFESRSAVLDRFAEALKSKI
: *. :