CLUSTAL format seed alignment for MF_00176
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
SYS_BUCAP ---MLNPYLLRNQIDAISKKL--LKK-KFKLDISLISSLEKKRKKLQIKTDNLQYKHNTL
SYS_BUCAI ---MLNPYLLRNELHLTAKKL--LKK-GYKLNISKISSMEEKRKTLQIQTENLQFKHNAL
SYS_ECOLI ---MLDPNLLRNEPDAVAEKL--ARR-GFKLDVDKLGALEERRKVLQVKTENLQAERNSR
SYS_HAEIN ---MIDPNLLRNNLAEVAEKLK-VKR-NFMLDTEKLTALEDQRKNLQVTTENLQAERNAR
SYS_BLOFL ---MLDTNLLFNHFEWVAKKL--ARK-NFVLNFDELNQYNDLRKILQKKIEKLQIDRKNL
SYS_COXBU ---MLDPKILRQNLEHVVEKL--RRR-GFEMDSDTFLQLENKRKEAQLAIQSFQTKRNQL
SYS_RICPR ---MLNIKWIRENQELFDEKL--SQR-FIEPMSSKIAMLDQEKRKITSLIQEFQHARKVK
SYS2_STRAW ---MHDPSELLEDGPAAVRRL--ARR-RYDLDLAALEKAVRRRSEAQAEVTRLRTELNRT
SYS_AQUAE ---MIDINLIREKPDYVKERLATRDK-ELVSLVDKVLELDKRRREIIKRLEALRSERNKL
SYS_THEMA ---MIDIKLIRQNPDFVKEALRKRG--EDPAIIDEILKIDADWRATITKTNELRSRRNEI
SYS_BACSU ---MLDTKMLRANFQEIKAKLVHKG--EDLTDFDKFEALDDRRRELIGKVEELKGKRNEV
SYS_STAA8 ---MLDIRLFRNEPDTVKSKIELRG--DDPKVVDEILELDEQRRKLISATEEMKARRNKV
SYS_HALMA ---MLSRQFVREHPETVRDAIE-RKG-VTGVDLDEILDIDEEWRELKAEGDGLRQERNEV
SYS_SYNY3 ---MLDLKQIRENPTAIQNRLNQRGG-GASYDLEPILAIAAEQKAKESERTVLQSRSNEI
SYS_HELPY ---MIDRKLLLQDFDKVALSLKKRNN-AMDDELERLREVITHYKKRLIELEGLQAFQNKV
SYS_HELPJ ---MIDRKLLLQDFDKVALSLKKRNH-AMDDELERLREAIAHYKKQLIELEGLQAFQNKV
SYS_MYCGE ---MLDPNKLRNNYDFFKKKLLERN--VNEQLLNQFIQTDKLMRKNLQQLELANQKQSLL
SYS_MYCPN ---MLDRNKLRNNLDFFKKKLVERG--VSESQFEAYVQADKAMRKLLHQIELANQKQTLL
SYS_MYCPU ---MLDLKKILNNPDYYRNILLNKK--ANISLFDELVKIGKKRGELMQKSQSLKAKINEL
SYS2_CLOAB ---MLDLDLIRNDTEKVKKAL--LKK-IDNVDFTELLKLDDERRKLIHEVEVLKNKKNEA
SYS_CHLTR ---MLDIRLIRKEPKECESRLQ--KK-DPAISLERLLDLDKTVRQLKADSEALLAKRKVL
SYS_CHLPN ---MLDIKIIRKTPEECETRLR--KK-DPKISLEPVLSLDKEVRQLKTDSETLQAQRRLL
SYS_THEAC ---MIDVKLLRSNRELFEKNCEYRG--VDKAPVEDFFRLDEEWRSINRELNGLRSQKNRE
SYS_THEVO ---MIDVKLLRSNRELFEKNCEYRG--VDKAIIDQFFKLDEEWRSVNRELNGQRAEKNRM
SYS_PYRAE -MSYSVLEALRNSPDVVRKVLTARR--MDASLVDKFLELDEKWRRLKKEVDELRHEYNKL
SYS_AERPE MAGWSILELLRSNPEALKEHVRKRL--MDPAIVDRAYRLDVEWRRLLTMVNEVRRRHNEI
SYS_ARCFU --MWSILKAVRENPEILYESQRRRG--LSVDIVDRAIELDRKWREELKRVNQLRKRRNEL
SYS_PYRHO ---MLDIKLIRENPELVKNDLIKRGELEKVKWVDEILKLDTEWRTKLKEINRLRHERNKI
SYS_MYCLE ---MIDLQLLREDPDVVRRSQLSRG--EDPALVDALLTADTARRAAISAADSLRAEQKAT
SYS_MYCTU ---MIDLKLLRENPDAVRRSQLSRG--EDPALVDALLTADAARRAVISTADSLRAEQKAA
SYS_COREF ---MIDLKFLRDNPDVVRTSQITRG--EDPALVDELLSADEARRQAIQVADELRSEQKAF
SYS_BIFLO ---MLDIQFIREHTDIVKESQRKRG--ESVELVDEVLSSDTARREALKAFEEARAQQKEI
SYS_STRCO ---MIDLRLLREDPDRVRASQRARG--EDVALVDSLLSADERRRSSGVRFDELRAEQKGL
SYS_TROWT ---MIDPEILVNTPDIVRLSQKKRG--ESQSIVEDALIARRNLRTAINNFETLRAEQNVL
SYS_BORBU ---MLDLKFIRDNLDLVKRSIKARG--LVLDIDKLIYLDDKRKKLITKIGELNAKRNENS
SYS_TREPA ---MLDYRFIRENVDAVKENVKVRN--VHADVDAIVHLYDQRVKLLAELQELQRARNENA
SYS_RHOBA ---MLDRKFILQNAQLVAENSAKRG--VSVDVDAICRLEAERMDALKQAEELNRQANEVS
SYS_THET2 ---MVDLKRLRQEPEVFHRAIREKG--VALDLEALLALDREVQELKKRLQEVQTERNQ-V
.
SYS_BUCAP SALFKKEKKI-QE----LDENLKRTLTKSSKNLSELKIELNLLQEKIHNFSLSIPNIPSD
SYS_BUCAI SNLFKENKNI-KN----KNELLRHQVIQSSKDLNASKIELNSLKEKIHHFSMCIPNIPSD
SYS_ECOLI SKSIGQAKAR-GE----DIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPAD
SYS_HAEIN SKAIGAAKAR-GE----DIAPLLAEMDDMGNQLTEAKAQLDAVLAEINQIALSIPNLPAD
SYS_BLOFL SKTIILAKSQ-QI----NLQSLQKQARLLNQKLILIKSEIRTLKSKIKQYQLSIPNIPDD
SYS_COXBU SKTIGMAKSK-GE----NPELLMAEVSQLNDELKQEEANFETIQKAFSDFQLAIPNLPHD
SYS_RICPR SKILGNMVSKSGE----EFEELQRDVNHINEKLAELEQNLDN-NNELNELLNMLPNIPDE
SYS2_STRAW SRARGRSGPP--------SEEEKEAARALRADVQQAEATARTAGHDLTELLLGIPNVPLD
SYS_AQUAE SKEIGKLKREGK-----DTTEIQNRVKELKEEIDRLEEELRKVEEELKNTLLWIPNLPHP
SYS_THEMA SKNVARLKKEGKN---AEAEALIEEGKRLGEEIKALEEKEKELQKKLNDLLLMIPNIPHE
SYS_BACSU SQQVAVLKREKK-----DADHIIKEMREVGEEIKKLDEELRTVEAELDTILLSIPNIPHE
SYS_STAA8 SEEIALKKRNKE-----NADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISD
SYS_HALMA SSKIGELKQDGKD---EEAQEAIDRSQELKDELQDIEERADELESQLEEALLELPNIPHE
SYS_SYNY3 GKLIGQKIGQGADPKGEEIQTLREEGNSLKIQLADLEPQEKDLKEQLQKLLLELPNLPCE
SYS_HELPY SKEFGIKMAQKVDT-----SDLKKELENNKIKLNELSKSVGELEQQIDLKLSIIPNLVDE
SYS_HELPJ SKEFGIKMAQKMDT-----SDLKKELENNKIKLNELSKSVGEAEQEMDLKLSIIPNLVDE
SYS_MYCGE AKQV-AKQKDNKK--------LLAESKELKQKIENLNNAYKDSQNISQDLLLNFPNIAHE
SYS_MYCPN AQQV-AKKKGDPK--------LLKESKELKQKLEQLNIAFKEAETLSQELLLNLPNIADE
SYS_MYCPU SKSF-IKLKTNEEK-----NELKAKISKIKKEQEQKEKKSELIDDRVFFLLANLPNIILD
SYS2_CLOAB SKQISNIKSQGGK----VDESFFKDIKEISNKISELETSLEPIKGKMDTFLEALPNIPDE
SYS_CHLTR SGQIHKAKVANEN-----ADALIQEVNTIADQLVAFETTLQEQEALLEDLMARLPNYPDE
SYS_CHLPN SQDIHKAKTQGVD-----ATNLIQEVETLAADLEKIEQHLDQKNAQLHELLSHLPNYPAD
SYS_THEAC TRKIAELIKNNGDASA-----EKKAVEDINARISDLENKLKKIEEERDRILWTIPNLVHE
SYS_THEVO TRAIAESLKRGKIVSN-----EKDRVELINEKIVSLEKKIREIEEERDRVLWTIPNLIHE
SYS_PYRAE SKEGAKAPP--ERRRE-----IADKARELAARLERAEKELEETERAREEVLWSFPNLIHE
SYS_AERPE TRMIAKAGSREERERL-----IAEAKRLLRER-EDLEEKLKKVEREREEALLGLPNIVAP
SYS_ARCFU ARAVKEAKG--EERAK-----VIEEAKAVSEEVKRAEEELKRLEAELEEVLLSIPNIIHE
SYS_PYRHO AVEIGKRRKKGEPVDE-----LLAKSREIVKRIGELENEVEELKKKIDYYLWRLPNITHP
SYS_MYCLE SKSLGAASA--EDRPA-----LLERAKDLAEQVKAAETTQAETAAAFAAAYMAISNVVLD
SYS_MYCTU SKSVGGASP--EERPP-----LLRRAKELAEQVKAAEADEVEAEAAFTAAHLAISNVIVD
SYS_COREF GKKIGQASP--EDRPA-----LLEGSNELKAKVKEAEAAQETAEQRVHDLQMKLSNVV-E
SYS_BIFLO GKKVASAPA--DEKAK-----LIAETKELSQKVSEYKSKADSAAEEYTTAMWKLSNIVEP
SYS_STRCO GKLIGKAAG--DEKAE-----LLKRAEQLKTDVKAADAERDAADAETQELLQRLGNLVHP
SYS_TROWT SKKIAGSED--SDRPE-----LMRVANLLAERVKNAREEQEKANSEWKKLLFEIPNIVSS
SYS_BORBU SKMQENLDK--VLKIS-----LIETGKILKKQLIDLEEELERVSVDFDLENKKVPNILSP
SYS_TREPA QTMKSSLDA--LARSA-----CVETGRALKDRIAHSERLLVQISDQLLSATQALPNMTHM
SYS_RHOBA KQIKSAKDN--DERQE-----LIAKGRSLREQKDAAGAAQDRLEAEILELQTILPNMTHP
SYS_THET2 AKRVPKAPP--EEKEA-----LIARGKALGEEAKRLEEALREKEARLEALLLQVPLPPWP
.
SYS_BUCAP DVPEGNSSENNKIVKYWGKK-----------------------REYSFAVRDHVEIGN-K
SYS_BUCAI DVPEGNTSINNKEIKYWGQK-----------------------KKYDFEIQDHIELGK-K
SYS_ECOLI EVPVGKDENDNVEVSRWGTP-----------------------REFDFEVRDHVTLGE-M
SYS_HAEIN EVPLGKDDTENKEILRWGTP-----------------------RTFDFEVKDHITLGE-E
SYS_BLOFL EIPNGFKDQDNIEIMRWGKV-----------------------HKYDFKLLDHITLGK-L
SYS_COXBU SVPDGKSENDNREIRQWGAP-----------------------PGFDFTPKDHTVLGE-R
SYS_RICPR EVPYGIDGSMNKLVRAYGKT-----------------------NKNALN-KQHFELGT-K
SYS2_STRAW SVPDGDTDQEAVEVRRWGRPP----------------------HDAGTDARHHSDIGE-S
SYS_AQUAE SVPVGEDEKDNVEVRRWGEP-----------------------RKFDFEPKPHWEIGE-R
SYS_THEMA SVPVGEDESQNVEVRRWGEP-----------------------REFDFTPLAHWDLGP-A
SYS_BACSU SVPVGETEDDNVEVRKWGEK-----------------------PSFAYEPKPHWDIAD-E
SYS_STAA8 DVPQGESDEDNVEVKKWGTP-----------------------REFSFEPKAHWDIVE-E
SYS_HALMA SVPTGEGEADNVERYREGFDDL---------------------RDLPDEVVPHYDLGE-D
SYS_SYNY3 TTPIGASEADNIEVKRWGDQYL---------------------KAETVGILPHWEIGE-K
SYS_HELPY KTPLGTNEEDNIEIKK-ILTP----------------------RVFTFKPKEHFELAQ-Q
SYS_HELPJ KTPLGASEEDNIEIKK-ILTP----------------------RNFTFKPKEHFELAQ-Q
SYS_MYCGE SVPVGKNESANLELLK-EGRK----------------------PVFDFKPLPHRELCE-K
SYS_MYCPN SVPVGRDETANLELLK-EGRK----------------------PVFDFTPLPHWELCE-R
SYS_MYCPU DVPFGEDENSNIVIEKKENLG----------------------NGLIVHDFSHYDIAE-K
SYS2_CLOAB DVLPGGKENNKVVHVYGEKP------------------------QFEFEPKDHVELSN-I
SYS_CHLTR DVPVSPDKTGNQVIKGHGEV-----------------------PTFPFPPKHHMQLNE-A
SYS_CHLPN DIPVSEDKAGNQVIKSVGDL-----------------------PIFSFPPKHHLELNQ-E
SYS_THEAC SVPVCFGDENNQLVRYVGHAKVFRDDIEEFKKNSGNS---QDYEVLDERPKSHVDLGL-D
SYS_THEVO SVPICFGDENNKIVRYVGHAKVYRDDEEEFLKGSGGN---GDYEVIDERPKSHVDLGQ-E
SYS_PYRAE SVPICPEGVDSIPVRHWGVVKTTKDVVDKLDKG-------VDYLVVEKAPVGHADMAEVV
SYS_AERPE DVPVGDES-ATRPIEFWGKPKVWKGHVDAFREQTEAYGFKVDHEVIEWRPRGHADMMEEV
SYS_ARCFU SVPVGKDDSENVPIKYWGKAKVYFEDVDAFVEMTQGM---AEYEVTDVKPIGHADAVE-I
SYS_PYRHO SVPVGKDENDNVPIRFWGKARVWKGHLERFLEQSQGK---MEYEILEWKPKLHVDLLE-I
SYS_MYCLE GVPTGG-KDDYAVLDIVGDP--------------------PPLSN----PKDHLELGE-A
SYS_MYCTU GVPAGG-EDDYAVLDVVGEP--------------------SYLEN----PKDHLELGE-S
SYS_COREF GAPAGG-EDDFVVLEHVGEP--------------------RTFDFE---PKDHLELGE-S
SYS_BIFLO EAPEGG-EDDYVVVKKVGQI--------------------RDFAAEGFEPKDHLTLGT-G
SYS_STRCO DVPVGG-EEDFVTLETHGTH--------------------RDFAAEGFEPRDHLELGQ-L
SYS_TROWT EAPYGV-EDKCAVMKTVGDI--------------------PEFDFE---PADHLQLGE-Q
SYS_BORBU DVPIGSSEEDNFEIKRVGVV--------------------PQFDFK---PKDHLELGR-D
SYS_TREPA CTPHGRSDSDNLEIKRCGVP--------------------PCFSFS---PRDHVELAR-L
SYS_RHOBA DVPEGGEHDANEIGRGKTPV--------------------PEMDFQ---PLDHLQLGE-K
SYS_THET2 GAPVGG-EEANREIKRVGGP--------------------PEFSFP---PLDHVALME-K
*
SYS_BUCAP LNQLDWKSSAKISGARFIVMKGNIALLHRALSQFMLDLHTIKHGYTETYVPYLVNHDSLY
SYS_BUCAI FNELDWKSSAQMSGSRFVIMKGKIALLHRALSQFMLDLHTLKHGYIESYVPYLVHSEALY
SYS_ECOLI HSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLY
SYS_HAEIN ANGLDFAAGAKLAGARFAVMKGQIAKMHRALAQFMLDLHTEQHGYLETYVPYLVNHATLY
SYS_BLOFL IGGIDLSSASKITGTRFIILKGEIAYLHRALSQFMIDIHIQNHGYIEYYLPYLINVESLY
SYS_COXBU DNQLDFEAAAKLSGARFVVLRGSLARAHRALAQFMLDLHTDQHGYEEVYVPYLVHEECLY
SYS_RICPR LNLMDFEQTAKISGSRFVTLKGDLAKLERALINFMIDIHTKEFDFFEISPPFLVRDRAMY
SYS2_STRAW LGILDGPAAAKLSGSRFSVGRGAGARLERALADFFLDLHTGEHGYTEYSVPFLVNRDTMT
SYS_AQUAE LGILDFKRGAKLSGSRFTVIAGWGARLERALINFMLDLHTKK-GYKEICPPHLVKPEILI
SYS_THEMA WGLMDFSRASKLSGSRFTVMYGKLARLERALINFMLDVHTKEHGYTEVWVPHLVKRETIT
SYS_BACSU LGILDFERAAKVTGSRFVFYKGLGARLERALYNFMLDLHVDEYNYTEVIPPYMVNRASMT
SYS_STAA8 LKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMY
SYS_HALMA LDLLDFERGAKVSGGGYQFVKGEGARLEHALIQFMLDVHREQ-EYVDVLPPIPVNSDSME
SYS_SYNY3 LGIIDSERGVKVAQSRFISLMKAGAALERALINFMLERHIGV-GYQEIMPPILVNSDSLL
SYS_HELPY NGWIDFESGVKLAKSRFSVIRGFGAKIYRALIHLMLDF-NEKNGFEIIYTPALVNEKMLF
SYS_HELPJ NGWIDFESGVKLAKSRFSVIRGFGAKIYRALIHLMLDF-NEKNGFEIIYTPALVNEKMLF
SYS_MYCGE LNLVAFDKATKISGTRFVAYTDKAAKLLRAITNLMIDL-NKSK-YQEWNLPVVINELSLR
SYS_MYCPN LQLVAFDKATKLTGARFVAYTDKAAKLLRAIASLMIDL-NKNK-YQEWNVPVIVNETSLT
SYS_MYCPU FGLVDFKRASKLSGPRFVIFKNQGAKLARALMDFMLDT-NIQKGYKEILPPFIVKGHNLF
SYS2_CLOAB HDLIDYKRGTKLSGNGFWIYKGYGAILEWALLNYFIEEHIKD-GYEFILPPHILNYECGR
SYS_CHLTR LQILDFKLPAKTTGSGWPAYCNEGVLLEWALLTYLLNK-QQAHGFQLWLPPLLVKRDILF
SYS_CHLPN LDILDFQAAAKTTGSGWPAYKNRGVLLEWALLTYMLQK-QAAHGFQLWLPPLLVKKEILF
SYS_THEAC LNVIDLESAARISGSRFYFIKNRLLKLEMALENYAVDFLSQR-GFSIVEPPYMLNLESMR
SYS_THEVO LGIIDLESAAKISGARFYFIKNRLLKLEMALENYAVDFLSQR-GFTVVEPPYMLNLESMR
SYS_PYRAE LKMADTLKAGEVAGSRFYYLFDDLVWLDFALAMYALDYLAQK-GFRPVIPPYMLKYDLIR
SYS_AERPE LKLGDTLRAARVAGSRFYYLFEDLVFLDLALLMYAIDFMTSK-GYVLVLPPYMLRYNVMS
SYS_ARCFU FGWADLERAAKVAGARFYYLLNDLVWLDFALTMYALDFLRKE-DFTIVSPPYMMRREAYS
SYS_PYRHO LGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDRLIEK-GFTPVIPPYMVRRFVEE
SYS_MYCLE LGLIDMQRGAKVSGSRFYFLTGRGALLQLGLLQLALRLAVEN-DFIPMIPPVLVRPEVMS
SYS_MYCTU LGLIDMQRGAKVSGSRFYFLTGRGALLQLGLLQLALKLAVDN-GFVPTIPPVLVRPEVMV
SYS_COREF LGLIDMKRGTKVSGARFYYLTGDGAMLQLGMLTLAAQKATAA-GFTMMIPPVLVRPEIMA
SYS_BIFLO VAGIDMRRGVKVGGSRFYFLRGQVARMQIAMLTMAVDQAEEH-GFTLAITPTLVRPEVMR
SYS_STRCO LGAIDVERGAKVSGSRFYFLTGVGALLELALVNAAIAQATAA-GFTPMLTPALVRPQSMA
SYS_TROWT LDAIDVSRGVKVSGTRFYFLKGWGARLELAVMNLALDLALKS-GLTLLITPTLVKPEIML
SYS_BORBU LDLLDFDRAREISGSKFYYLKNEAVFLEIALINFSLNKLRDK-GFDVFITPDVAREFIVD
SYS_TREPA LDIVDFEAGKKVSGIKFYYLKREGVLLEQALIMFGLQFLQER-GFVPFLTPDIAREGMVC
SYS_RHOBA HDLFDFEGGARVAGSGFYFLRNAAVRLDLALQQFAISHLAGK-GFTPVSTPDLALTSVLQ
SYS_THET2 NGWWE-PRISQVSGSRSYALKGDLALYELALLRFAMDFMARR-GFLPMTLPSYAREKAFL
. .: *
SYS_BUCAP GTGQLPKFTDDLFHINSIDKK------KYVLIPTAEVPLTNLFSNQILNETELPIMLTAH
SYS_BUCAI GTGQLPKFSDDLFHINLTDKK------KYILIPTGEVPLTNLVYDQIIDEKDLPIMLTAH
SYS_ECOLI GTGQLPKFAGDLFHTRPLEEEADT--SNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAH
SYS_HAEIN GTGQLPKFGEDLFHTLALEGE-----QPYALIPTAEVPVTNLVRDVIIDEAELPIKMTAH
SYS_BLOFL GSGQLPKFYDDLFHTQSVVSVNSSKCSTYTLIPTAEVPLVNIMRSVTVHKNELPIKMVAH
SYS_COXBU GTGQLPKFREEQFQVAGDRN--------FFLVPTGEVPLVNLARDEIIEAPALPKKWVAQ
SYS_RICPR NAGQLPKFSEESFITT----------NGYRLIPTAEVSLVNIVADTIIQREKLPMRYVAY
SYS2_STRAW GTGQLPKFEDDLFRTQVGDRE-------LFLIPTAEVPLTNLVAQQLLDARALPYAFTAR
SYS_AQUAE GTGQLPKFEEDLYKCER---------DNLYLIPTAEVPLTNLYREEILKEENLPIYLTAY
SYS_THEMA ITGQLPKFEEELYLAER---------DDLFLIPTAEVPLAALHSGEILEEKELPKKYVSY
SYS_BACSU GTGQLPKFEEDAFKIRE---------EDYFLIPTAEVPITNMHRDEILSGDSLPINYAAF
SYS_STAA8 GTGQLPKFEEDLFKVEK---------EGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQ
SYS_HALMA GTGQLPKFAEDAYRVGARQDDDYD-SDDLWLLPTAEVPVTNMYRGEILLDDDLPVKHQAF
SYS_SYNY3 GTGQLPKFAEESFQCRG---------DDLWLIPTAEVPVTNLYRDEVLDLEQLPIKHCAY
SYS_HELPY GTGQLPKFKEDVFKIENE---------NLYLIPTAEVTLTNLYNDTIISVENLPIKMTAH
SYS_HELPJ GTGQLPKFKEDVFKIENE---------NLYLIPTAEVTLTNLYNDTIISVENLPIKMTAH
SYS_MYCGE STGQLPKFKDDVFKLENT---------RYYLSPTLEVQLINLHANEIFNEEDLPKYYTAT
SYS_MYCPN GTGQLPKFKDDVFKLENT---------RYYLSPTLEVQLANLHANEIFTEGELPKYYTAT
SYS_MYCPU GTGQLPKFEEDLFKLEN----------GMYLIPTAEVPVTNYYNDEIINLD-KPKMFVSF
SYS2_CLOAB TAGQFPKFKDEVFKVGSNGEGE----GMQFILPTAETALVNLHRDEILKEDELPKKYFAY
SYS_CHLTR GSGQIPKFDGQYYRVEDGD-------QSLFLIPTAEVVLNGFHSQEILNEQDLPLCYAAF
SYS_CHLPN GSGQIPKFDGQYYRVEDGE-------QYLYLIPTAEVVLNGFRSQDILTEKELPLYYAAC
SYS_THEAC GATDLETFKDTLYKIEG---------EDLYLIATSEHSIAAMLSNQFLEEKDLPLRVAGI
SYS_THEVO GATDLETFKDTLYKIED---------EDLYLIATSEHSIASMLSNEFLEEKELPIRVAGV
SYS_PYRAE RVLDFDTFKDAIYKIDG---------EDLYLIATAEHGIAAYLYKRELLEEELPQLYVGW
SYS_AERPE RVIDLETFKDAIYEIAG---------EDLYLIATAEHPLAALYYNSEIYDEDLPLKLVGV
SYS_ARCFU GVTAFSDFEEVIYKVED---------EDLYLIATSEHPIAAMHMREVLEERELPLLYAGV
SYS_PYRHO GSTSFEDFEDVIYKVED---------EDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGV
SYS_MYCLE GTGFLGAHAEEVYRV-----------DDLYLVGTSEVPMAGYHSDEILDLSVGPLRYAGW
SYS_MYCTU GTGFLGAHAEEVYRVEG---------DGLYLVGTSEVPLAGYHSGEILDLSRGPLRYAGW
SYS_COREF GTGFLGDHSEEIYYLER---------DDMYLVGTSEVALAGYHKDEIIDLNNGPVKYAGW
SYS_BIFLO GTGFLNSHADEIYRLREP--------DDQYLVGTSEVALAGMHENEILDLGNGPLRYCGW
SYS_STRCO GTGFLGQAAQDVYHLDK---------DDLYLVGTSEVPLAAYHMDEILDGDRLPLRYAGF
SYS_TROWT GTGFLGRHEGEVYRLPS----------GYYLTGTSEVAIAGYHSDEILDISSGPIRYAGW
SYS_BORBU GIGFNPRGNESNIYKIED--------TDKYLVGTSEITLGGYYYNKIID-LTLPIRMAGF
SYS_TREPA GLGFNPRGSGSNIYRIEG--------EHRCLVATAEITLGAYHAGEVLEERSLPRLYAGL
SYS_RHOBA GTGFNPRGPETQIYSIEN--------TELNLVATAEIPLGGMLSGQILASEELPLRYCGL
SYS_THET2 GTGHFPAYRDQVWAIAE---------TDLYLTGTAEVVLNALHSGEILPYEALPLRYAGY
* * : . * .
SYS_BUCAP TPCFRSEASSYGRDSKGLIRLHQFDKVELVQIIQP--ELSMNALELLTHHAEKVLQLLEL
SYS_BUCAI TPCFRSEASSYGRDTKGLIRLHQFDKVELVQIVKP--EKSYEALEKLTNHAEKVLQLLNL
SYS_ECOLI TPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRP--EDSMAALEEMTGHAEKVLQLLGL
SYS_HAEIN TPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVDP--DKSMEALEELTGHAEKVLQLLNL
SYS_BLOFL TPCFRLEAGTYGYRAHGLIRTHQFDKVELVQVVHP--DQSVQALEEITNHAEKILQLLEL
SYS_COXBU TPCFRSEAGSYGKDVRGMIRQHQFQKVELVQLVQP--ENSYQALEEITRQAEKVLQLLAL
SYS_RICPR TTCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTP--EESKNEHEYITNASETILKKLDL
SYS2_STRAW TPCFRAEAGAYGRDTRGILRLHQFEKVELVRVCAP--EDAPAQLELMVGHAEECLRRLEL
SYS_AQUAE TPCYRREAGAYGKDIRGIIRQHQFDKVELVKIVHP--DTSYDELEKLVKDAEEVLQLLGL
SYS_THEMA TPCYRREAGSYGKDVRGMIRQHQFDKVELVWVTTP--ERSFEDLEELVKDAETILRKLEL
SYS_BACSU SACFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKP--EDSYEELEKLTNQAERVLQLLEL
SYS_STAA8 SACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQP--EDSWNALEEMTTNAEAILEELGL
SYS_HALMA SPNFRREAGEHGTETRGYVRVHQFHKVELVNFVRP--ENSYDRLESLLDEAAEVLDRLEL
SYS_SYNY3 TPCFRREAGSYGRDTKGLIRLHQFNKVELVKLVKP--EESAAEHQALVADAEAILQALEL
SYS_HELPY TPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHP--KESDVMQEHMLESASEILKALEL
SYS_HELPJ TPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHP--KESDAMQEHMLESASEILKALEL
SYS_MYCGE GINFRQEAGSAGKQTKGTIRLHQFQKTELVKFCKP--ENAINELEAMVRDAEQILKALKL
SYS_MYCPN GVNFRQEAGSAGKQTKGTIRLHQFQKVELVKFCKP--SEAIHELEEMTRDAEQILLELKI
SYS_MYCPU TECFRSEAGSGGKDNRGLIRSHQFKKVEIVKITNE--QDGIKEFEKTIEDASHLLELLEI
SYS2_CLOAB TPCYRVEAGSYRASERGMIRGHQFNKIEMFQYTKP--EDSDAALEELIGKAEKLVKGLGL
SYS_CHLTR TPCFRREAGAGGAHERGLVRVHQFHKVEMFAFTTP--EQEEVVYQKMLHVVEEILSELQL
SYS_CHLPN TPCFRREAGAAGAQERGLVRVHQFHKVEMFAFTTP--NQDDIAYEKMLSIVEEMLTELKL
SYS_THEAC SACFRREAGAHGKDTKGIFRVHQFNKIEQFVFCKP--EDSWDFLEEILGNAEAIYRSLGI
SYS_THEVO SACFRREAGAHGKDTKGIFRVHQFNKIEQFIFCKP--EDSWDYLEEILSNAEEIYRSLGI
SYS_PYRAE SPCFRKEAGAGSRDIKGIFRVHIFHKVEQFVFSLP--EDSWKWHEEITKNTEELIRGLGL
SYS_AERPE SPCFRKEAGAGNRDLKGIFRVHQFHKVEQFVYSLP--EESSKLHEELISNAKEIFKGLEI
SYS_ARCFU SPCFRKEAGAHGKDTKGIFRVHQFNKVEQFVFCLP--EQSWEWHEKLIENVEKLWQGLGI
SYS_PYRHO SPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRP--EESWEWHEKIIRNAEELFQELEI
SYS_MYCLE SSCFRREAGSHGKDTRGIIRVHQFDKVEGFVYCAP--TDAEVEHQRLLGWQREMLARIEV
SYS_MYCTU SSCFRREAGSHGKDTRGIIRVHQFDKVEGFVYCTP--ADAEHEHERLLGWQRQMLARIEV
SYS_COREF SSCFRREAGSYGKDTRGILRVHQFDKVEMFVYCKP--EEAEEQHRRLLEMEKDMLAAVEV
SYS_BIFLO SSCYRREAGAAGKDTSGIIRVHQFDKVEMFVYAKQ--EDSYKEHEHLLAMEQEMLAKVEV
SYS_STRCO SPCFRREAGSHGKDTRGIFRVHQFDKVEMFSYVLP--EDSQAEHQRLLEWEKQWLTSLEL
SYS_TROWT SSCYRREAGSHGRDTRGIMRVHQFSKLEMFSYVHP--QQSTRELEHIVSMQEKMLNLLEI
SYS_BORBU SHCFRKEAGAYGQLSKGLYRVHQFSKVEMFCFCKA--EESGVIHDEFLSIQEQIFTELEI
SYS_TREPA SHCFRKEAGAAGQFSRGLYRVHQFTKLEMFAYCTP--SDSECLHERLRSLEEEIFTALEI
SYS_RHOBA SHCFRTEAGAAGRASKGLYRVHQFTKVEMFAFTLP--DQSTAMHEEMRELECEIFDALEV
SYS_THET2 APAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLEL
:* **. * * * * * * : :
SYS_BUCAP PYRKVLLCGGEMGFSATKTYDLEVWFPSQKK---------YREISSCSNMSDFQARRMKT
SYS_BUCAI PYRKMLLCTGDTGFAAVKTYDLEVWFPSEKK---------YREVSSCSNMSDFQARRIKA
SYS_ECOLI PYRKIILCTGDMGFGACKTYDLEVWIPAQNT---------YREISSCSNVWDFQARRMQA
SYS_HAEIN PYRKVLLCTGDMGFGSCKTYDLEVWVPAQNT---------YREISSCSNMWDFQARRMQA
SYS_BLOFL PYRKMLLCAGNISFTSCKTYDLEVWLPARNE---------YCEISSCSNIRDFQSRRINA
SYS_COXBU PYRVVELCAGDLGFAAAKTYDLEVWLPSQNK---------YREISSCSNCEDFQARRIQA
SYS_RICPR PYRVMLLCTGDMGFAAKKTYDIEVWLPGQNQ---------YREIASCSNCGDFQARRMKA
SYS2_STRAW SYRVVQLPAGDLGFSARMTYDIEVWLPGSDA---------YREISSVSDCGTFQARRADI
SYS_AQUAE PYRVVELCTGDLGFSAAKTYDIEVWFPSQNK---------YREISSCSNCEDFQARRMNT
SYS_THEMA PYRVVSLCTGDLGFTSAKTYDIEVWLPSYNA---------YKEISSCSNVTDFQARRGNM
SYS_BACSU PYRVMSMCTGDLGFTAAKKYDIEVWIPSQDT---------YREISSCSNFEAFQARRANI
SYS_STAA8 PYRRVILCTGDIGFSASKTYDLEVWLPSYND---------YKEISSCSNCTDFQARRANI
SYS_HALMA PYRVLDMCTGDMGFTQAKKYDIEVWAPGDDMEDGPDRGGRWLEVSSVSNFEDFQARRAGL
SYS_SYNY3 PYRVVELCTGDLGFGAAKCYDLEVWLPSANT---------YREISSCSNFHDFQARRANI
SYS_HELPY PHRFVQLCSGDLGFSASNTIDIEVWLPGQNC---------YREISSVSNTRDFQARRAKI
SYS_HELPJ PHRFVQLCSGDLGFSASNTIDIEVWLPGQNC---------YREISSVSNTRDFQARRAKI
SYS_MYCGE PFRRLLLCTGDMGFSAEKTYDLEVWMAASNE---------YREVSSCSSCGDFQARRAMI
SYS_MYCPN PFRRLLLCSGDMGFSAQKTYDLEVWMAGCNE---------YREVSSCSSCGDFQARRAMI
SYS_MYCPU PYQKVLLCSGDTSFSSMKTIDLELWLPSEKR---------FRETSSISYFGDFQGRRAKI
SYS2_CLOAB HYRLSKLAAADCSASMAKTYDIEVWIPSMNE---------YKEVSSASNARDYQARRGKI
SYS_CHLTR PYQLSLLSTGDMSFTAKKTIDAEVWLPGQKA---------FYEVSSISKCGDFQARRSET
SYS_CHLPN PYRLSLLSTGDMSFTASKTIDAEVWLPGQKA---------FYEVSSISQCTDFQSRRSGT
SYS_THEAC PYRVVNVCSGELGRLAAKKYDIEAWFP---AQ------GKFREIVSASNDTDYQARSLNI
SYS_THEVO PYRVVNVCSGELGRLAAKKYDIEAWFP---AQ------GKFREIVSASNDTDYQARSLNI
SYS_PYRAE PYRVVNICAHDLGAPAAKKYDIEVWYP---SQ------GMYRELASCSNVTDWQSYRLGI
SYS_AERPE PFRVVNIASGDLGACAVKKYDLEAWMP---AQ------GKYREMVSASNCTDWQAYRLGI
SYS_ARCFU PYRIVNICTGDLGIVAAKKYDLEAWMP---AQ------AKYREMVSCSNCTDWQSYRLDI
SYS_PYRHO PYRVVNICTGDLGYVAAKKYDIEAWMP---GQ------GKFREVVSASNCTDWQARRLNI
SYS_MYCLE PYRVIDVAAGDLGSSAARKFDCEAWVP---TQ------GSYCELTSTSNCTTFQARRLAT
SYS_MYCTU PYRVIDVAAGDLGSSAARKFDCEAWIP---TQ------GAYRELTSTSNCTTFQARRLAT
SYS_COREF PYRIIDVAGGDLGASAARKFDTEAWVP---TQ------GTYRELTSTSNCTTFQGRRLQT
SYS_BIFLO PYRIIDTAAGDLGSSAARKFDCEAWVP---TQ------GRYRELTSTSNCTEYQARRLNI
SYS_STRCO PFRVIDVASADLGSSAARKYDCEAWIP---TQ------GKYRELTSTSDCTEFQSRRLSI
SYS_TROWT PYRVSDIAAEELGTSASRKYDLEAWIP---SQ------NTWREVTSASDCTTFQARRLNV
SYS_BORBU PYRVLNICSFDLGSPAYKKYDIEAWMPGRDGK------GGYGEVTSTSNCTDYQSRRLKI
SYS_TREPA PFRVVEVCAGDLGAPAYRKWDLEAWMPGRQG-------GSWGEVTSASNCTDYQARRLNV
SYS_RHOBA PYRVIDTATGDLGGPAYRKYDLEAWMPGRGES------GDWGEVTSTSNCTDYQARRLNV
SYS_THET2 PYRLVEVATGDMGPGKWRQVDIEVYLP---SE------GRYRETHSCSALLDWQARRANL
.: : . * * : . : * * * :*.
SYS_BUCAP RYKKKKEKSN-SFVHTLNGSGLAIGRTLAAILENYQDSD-GRVTIPKILQKKYMQGIEYI
SYS_BUCAI RYRKKSEQKN-FFVHTLNGSGLAIGRTLAAILENYQHSN-GRIEIPKVLQKKYMQGLEFI
SYS_ECOLI RCRSKSDKKT-RLVHTLNGSGLAVGRTLVAVMENYQQAD-GRIEVPEVL-RPYMNGLEYI
SYS_HAEIN RCKAKGDKKT-RLVHTLNGSGLAVGRTLVAVLENYQNAD-GSITVPEEL-RPYMGGLDVI
SYS_BLOFL RFKDGINKRS-KLLHTLNASGVAVGRALVAILENYQLEN-GCIKIPEVL-SPYMNGMTHI
SYS_COXBU RWRNPKTGKP-ELLHTLNGSGLAVGRTLVAVMENYQQAD-GHIRVPDAL-KSYMGGVDYF
SYS_RICPR RYKEFGSNET-TLVHTLNASGLPIGRTIVAILENYQNND-GSITIPDVL-INYMGGLQKI
SYS2_STRAW RHKRADGRK--APAATLNGSALPIGRTVAALLEQGVRED-GSVLLPEAL-VPYTGFRRIL
SYS_AQUAE RFKDSKTGKN-RFVHTLNGSGLAVGRTLAAILENYQQED-GSVVVPEVL-RDYVGTDVIR
SYS_THEMA RYRRRSDGKL-EYVHTLNGSGIAVGRALVAILENYQQPD-GSVRVPEVL-VPYTGFEVIP
SYS_BACSU RFRREAKGKP-EHVHTLNGSGLAVGRTVAAILENYQQED-GSVVIPKVL-RPYMGNR-EV
SYS_STAA8 RFKRDKAAKP-ELAHTLNGSGLAVGRTFAAIVENYQNED-GTVTIPEAL-VPFMGGKTQI
SYS_HALMA RYRPERHESA-DYLHTLNGSGLAVPRVLVAIME-YYQNDDGTITVPEPL-RPYMGGQEVI
SYS_SYNY3 RYKEKGKKGT-QFVHTLNGSGLAIGRTMAAILENYYEPSSGQVKVPVVL-QDFLKRDYL-
SYS_HELPY RFKENQ--KN-QLAHTLNGSSLAVGRTMVALME-NHQQADGSIHIPKAL-EKYL------
SYS_HELPJ RFKENQ--KN-QLVHTLNGSSLAVGRTMVALME-NHQQADGSIHIPKAL-EKYL------
SYS_MYCGE RYKDINNGKN-SYVATLNGTALSIDRIFAAILE-NFQTKDGKILIPQAL-KKYLDFDTIK
SYS_MYCPN RYKDLTTGKN-TYVATLNGTALAIDRIFAAILE-HYQTKAGEVMIPQAL-LKYLDFDKIT
SYS_MYCPU RYKQND--KT-YFAHTINGSALAIDRVFAALIELNYDSKNELIKIPEKL-VPYFGSSQIA
SYS2_CLOAB RFRREETKKI-EYVNTLNASGLATSRVLPAILEQMQDKD-GSIVVPEVL-RKWVGKDKL-
SYS_CHLTR RYRDAQ-GKL-HFVNTLNGSGLATPRLLVAILENYQQAD-GSVVIPSVL-RPYMNNQEIL
SYS_CHLPN RYKDSQ-GKL-QFVHTLNGSGLATPRLLVAILENNQQAD-GSVVIPEVL-RPYLGGLEIL
SYS_THEAC KYRTSEGN---RFVHTLNSTAIATTRILVAIME-NFQ-EGDRIRIPDVL-VPYTGFQYIE
SYS_THEVO KYRKSGGN---EFVHTLNSTAIATTRILVAIME-NFQ-EDGRIRIPDVL-VPYTGFQYID
SYS_PYRAE RVTR-KGMKR-EYVHTLNCTGLATTRTITAILE-NFQREDGAVEIPKVL-RQYLEPIKAA
SYS_AERPE RLVRRKGMER-GYVHTLNATAVASTRTITAILE-NFQDEEGVVAIPRAL-RRYLEVFKRA
SYS_ARCFU RFAEERGKPSKGFVHTLNSTAIATTRAITAIIE-NFQLEDGRVEIPRVL-RKYLEPIESA
SYS_PYRHO RFRDRTDEKP-RYVHTLNSTAIATSRAIVAILE-NHQEEDGTVRIPKVL-WKYTGFKEIV
SYS_MYCLE RYRDASGKP--QIVATLNGTL-GTTRWLVAILE-NHQRPDGSVRVPPAL-VPFVG-TELL
SYS_MYCTU RYRDASGKP--QIAATLNGTL-ATTRWLVAILE-NHQRPDGSVRVPDAL-VPFVG-VEVL
SYS_COREF RYRDENGKP--QIAATLNGTL-ATTRWLVAILE-NNQQADGSVIVPEAL-RPFVG-KDVL
SYS_BIFLO RERMEDGGT--RPVSTLNGTL-ATTRWLVAIME-NHQQKDGSIEIPKAM-RAYMGGKEVI
SYS_STRCO RVR-EGKKV--RPLATLNGTLCAVPRTIVAILE-NHQQADGSVRVPEVL-RPYLGGREVL
SYS_TROWT RYRDESGRT--GYVATLNGTL-ATTRFLVAILE-NHQTSNGSIRVPEAL-RPLLG-QDVI
SYS_BORBU RYK-DQDGQN-KFAHMVNGTAIATTRVIISILE-NFQDQKGGVRIPKSL-VKYTGFDYIP
SYS_TREPA RYK-DAEGKK-HYVHMLNGTALAISRVLIALLE-NGQDAEGRVRIPQAL-VPFCGFEYLY
SYS_RHOBA RSKSNTQKGT-DFVHTLNGTAIATGRAMIAILE-NHQRADGTINVPEIL-RPWVGCDVLK
SYS_THET2 RYR-DPEGRV-RYAYTLNNTALATPRILAMLLE-NHQLQDGRVRVPQAL-IPYMGKEVLE
: :* : * . ::* : :* :
SYS_BUCAP N----------------
SYS_BUCAI N----------------
SYS_ECOLI G----------------
SYS_HAEIN GK---------------
SYS_BLOFL HYQNK------------
SYS_COXBU -----------------
SYS_RICPR TTYSE------------
SYS2_STRAW PGGATA-----------
SYS_AQUAE PE---------------
SYS_THEMA -----------------
SYS_BACSU MKP--------------
SYS_STAA8 SKPVK------------
SYS_HALMA EGSEKIGESAVGAGEKE
SYS_SYNY3 -----------------
SYS_HELPY -----------------
SYS_HELPJ -----------------
SYS_MYCGE -----------------
SYS_MYCPN KPK--------------
SYS_MYCPU RK---------------
SYS2_CLOAB -----------------
SYS_CHLTR LPKTVR-----------
SYS_CHLPN LPKDQ------------
SYS_THEAC KG---------------
SYS_THEVO KE---------------
SYS_PYRAE PKDYILPKAAKSP----
SYS_AERPE PTDAIHPRRRPPA----
SYS_ARCFU PKDFIMPAKSQ------
SYS_PYRHO PVEKKERCCAT------
SYS_MYCLE ESPR-------------
SYS_MYCTU EPVA-------------
SYS_COREF EPVK-------------
SYS_BIFLO EPTKWEA----------
SYS_STRCO EPVAK------------
SYS_TROWT ER---------------
SYS_BORBU FKN--------------
SYS_TREPA PRVL-------------
SYS_RHOBA CE---------------
SYS_THET2 PCG--------------