CLUSTAL format seed alignment for MF_00548

_____________________________________________________________________________

Features found in the protein:
The following colors are used to highlight features:
blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
magenta is used to display DISULFID, THIOLEST and THIOETH.
red is used for all other features, such as INIT_MET, ACTIVE SITE,
 METAL,BINDING, NP_BIND, SITE, REGION, etc.
The ID of the sequence used as the template for feature propagation is 
underlined.
A '<' at the beginning of a sequence or '>' at the end indicate that
 the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________

ZUPT_SHIF8      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_SHIFL      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_SHISS      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_ECOHS      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_ECOLC      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_ECOLI      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_ECOL5      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_ECO24      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_ECO57      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_ECOL6      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_ECOK1      ---------MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLME
ZUPT_SHIDS      ---------MSVPLILTILAGAATFIGAFLGVLGQKTSNRLLAFSLGFAAGIMLLISLME
ZUPT_SALTI      ---------MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLME
ZUPT_SALTY      ---------MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLME
ZUPT_SALPB      ---------MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLME
ZUPT_SALCH      ---------MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLME
ZUPT_SALPA      ---------MSVPLILTLLAGAATFIGAFLGVLGQKPSNRMLAFSLGFAAGIMLLISLME
ZUPT_SALAR      ---------MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLME
ZUPT_ENT38      ---------MSVPLILTLLAGAATFIGAILGVIGQKPSNRVLAFSLGFAAGIMLLISLME
ZUPT_NEIMF      -MPDFSMSNLAVAFSITLAAGLFTVLGSGLVMFSKTPNPRVLSFGLAFAGGAMVYVSLTE
ZUPT_NEIMA      -MPDFSMSNLAVAFSITLAAGLFTVLGSGLVMFSKTPNPRVLSFGLAFAGGAMVYVSLTE
ZUPT_NEIMB      -MPDFSMSNLAVAFSITLAAGLFTVLGSGLVMFSKTPNPRVLSFGLAFAGGAMVYVSLTE
ZUPT_XANAC      -MLAVSSHNLWIALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVYVSLTE
ZUPT_XANCP      -MLEVSSHNVWTALAVTLAAGLATGLGSLMVVFAKKPNPRLLAFGLAFAGGAMVFVSLSE
ZUPT_STRMU      -----MSQHLFTAFILTALAGLSTGIGSLIAFVTKHTNKTFLSVSLGFSAGVMIYVSMIE
ZUPT_CLOPE      MKGGDNMNNVLMAFLLTLLAGLATGIGSCIAFFAKKTNKKFLCVSLGFSAGVMIYVSMIE
ZUPT_CHLCH      -----MTDNILFAFALTLFAGLSTGVGSLIGLLSKEFNPKVLTISLGFSAGVMIYVAMIE
ZUPT_OCEIH      ------MDNMLLAFLLTLFAGLATGVGSLIAFMAKTTNTKFLSFALGLSAGVMIYVSMVD
ZUPT_COREF      ----MDWSNIIFAFSLTLFAGLATGVGGVIAVARKAPGERFLAGSLGFSVGVMLFVSFVE
ZUPT_CORGL      ---------MLFAFGLTLFAGLATGIGGLIAVARKTVTEGFLAGSLGFSVGVMLYVSFVE
ZUPT_CAMJE      --MQFTFEQIFIAMLLTLFAGFSTAIGSIIAFFSRKDDLRVLSLGLGFSAGVMIYISFME
                         :  .: :*  **  * :*. : .  :     .*  .*.:: * *: ::: :

ZUPT_SHIF8      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_SHIFL      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_SHISS      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_ECOHS      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_ECOLC      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_ECOLI      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_ECOL5      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_ECO24      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_ECO57      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_ECOL6      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_ECOK1      MLPAA------LAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQK---------
ZUPT_SHIDS      MLPAA------LAAEGMSPVLGYGMFIFGLLGYLGLDRMLPHAHPQDLMQK---------
ZUPT_SALTI      MLPAA------LDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQK---------
ZUPT_SALTY      MLPAA------LDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQK---------
ZUPT_SALPB      MLPAA------LDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQK---------
ZUPT_SALCH      MLPAA------LDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQK---------
ZUPT_SALPA      MLPAA------LDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQK---------
ZUPT_SALAR      MLPAA------LDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVPK---------
ZUPT_ENT38      MLPAA------LRTDGMSPVMGYGMFVVGLLGYFALDKMLPHAHPQDLMQK---------
ZUPT_NEIMF      IFSKSSEAFAEIYDKDHAFAAATMAFLAGMGGIALIDRLVP---NPHETLD-------AQ
ZUPT_NEIMA      IFSKSSEAFAEIYDKDHAFAAATMAFLAGMGGIALIDRLVP---NPHETLD-------AQ
ZUPT_NEIMB      IFSKSSEAFAEIYDKDHAFAAATMAFLAGMGGIALIDRLVP---NPHETLD-------AQ
ZUPT_XANAC      ILNKSIAAFSQAYNDKLGFTFGTLTFLGGMLLIMVIDRLVP---NPHQSLS-------SD
ZUPT_XANCP      ILNKSIASFSNAYNDKLGFTYGTLTFLGGMLLIMVIDRLVP---NPHQSLS-------TD
ZUPT_STRMU      IFPTAQTILTKAMDKKSGSWLTVLAFFGGILLIAIIDKLIPSEENPHEIKT-------IE
ZUPT_CLOPE      MFQTAKESLVGVMGIKAGNWITVISFFAGIAIIALIDKFVPEEENPHEVRS-------VE
ZUPT_CHLCH      IMVKARESLVVGIGAEMGKVVTVLSFFAGIFLIALIDKLIPSYENPHELNV-------AQ
ZUPT_OCEIH      IFFKAKDALTAYLGDTQGYWLTVIAFFGGMLLIGFIDRFIPKYTNPHEVKK-------VE
ZUPT_COREF      ILPKAVEELTGVWGERGGNWAATGAFFAGIALIAVIDRLVPTAINPHEPST-------VG
ZUPT_CORGL      ILPGAFDELTSVWGEKGGSWAAVIGFFGGIALIAIIDRLVPTAINPHEPST-------VG
ZUPT_CAMJE      ILPTALKDFKNHYDSHWAELLGLACFFGGILISLLIDKLIPEDVNPHEPKEDLSELKICP
                ::  :            .       *. *:     :*:::*     .             

ZUPT_SHIF8      ----------------SVQLLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SHIFL      ----------------SVQLLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SHISS      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ECOHS      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ECOLC      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ECOLI      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ECOL5      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ECO24      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ECO57      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ECOL6      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ECOK1      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SHIDS      ----------------SVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SALTI      ----------------RQQPLPGSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SALTY      ----------------RQQPLPGSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SALPB      ----------------RQQPLPGSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SALCH      ----------------RQQPLPGSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SALPA      ----------------RQQPLPGSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_SALAR      ----------------RQQPIPGSIKRTAVLLTLGISLHNFPEGIATFVTASSNLELGFG
ZUPT_ENT38      ----------------NAKPTRGNIKRTAILLTLGISLHNFPEGVATYVTASNNLELGFG
ZUPT_NEIMF      DPSFQ-------------ESKRRHIARVGMMAAFAITAHNFPEGLATFFATLENPAVGMP
ZUPT_NEIMA      DPSFQ-------------ESKRRHIARVGMMAAFAITAHNFPEGLATFFATLENPAVGMP
ZUPT_NEIMB      DPSFQ-------------ESKRRHIARVGMMAAFAITAHNFPEGLATFFATLENPAVGMP
ZUPT_XANAC      DPQFR-------------EDNRAYIRRVGLMTAVAITAHNFPEGLATFFATLESPAVGMP
ZUPT_XANCP      DPQFR-------------DDNRAYIRRVGLLTAVAITAHNFPEGLATFFATLESPAVGMP
ZUPT_STRMU      E----------------EDQKPTKLMRMGLMTAIAIGIHNFPEGLATFISGLQDASIAIP
ZUPT_CLOPE      EVENEIEEYKGENKEGKADIKDKTLMRTGIVTALAIAIHNFPEGLATFVSALEGASLAIP
ZUPT_CHLCH      KLEE------------CSENQKKKLMRMGLFSAVAIGIHNFPEGLATFMSGLSNPTLGVS
ZUPT_OCEIH      DMKKP-----------HQPLRDPDLMKMGLFTALALAIHNFPEGIATFVSTLHDPSIGLA
ZUPT_COREF      GAVE-------------GYERRSRMMRAGVLTAIAISIHNFPEGFATFVAGLTDPRIAIP
ZUPT_CORGL      GAVE-------------GFERRNRMMKMGVLTALAIAIHNFPEGFATFLAGLSDPMIAIP
ZUPT_CAMJE      LPQKGQNPPKFHPGEKLHQINTKALKRTGIFTALAIAIHNFPEGFATFISSLDNLTLGIA
                                        : : .:. :..:  ******.**:.:   .  :.. 

ZUPT_SHIF8      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_SHIFL      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_SHISS      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_ECOHS      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_ECOLC      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_ECOLI      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_ECOL5      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_ECO24      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_ECO57      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_ECOL6      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_ECOK1      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_SHIDS      IALAVALHNIPEGLAVVGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVV
ZUPT_SALTI      IALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIV
ZUPT_SALTY      IALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIV
ZUPT_SALPB      IALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIV
ZUPT_SALCH      IALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIV
ZUPT_SALPA      IALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIV
ZUPT_SALAR      IALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMAEIFGGVLAWLILGSLVSPIV
ZUPT_ENT38      IALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLTWLILGSMISPVV
ZUPT_NEIMF      LALAIAIHNIPEGISIAAPVYFATRSRKKTVWACLLSGLAEPLGAALGYLVLQPFLSPAV
ZUPT_NEIMA      LALAIAIHNIPEGISIAAPVYFATRSRKKTVWACLLSGLAEPLGAALGYLVLQPFLSPAV
ZUPT_NEIMB      LALAIAIHNIPEGISIAAPVYFATRSRKKTVWACLLSGLAEPLGAALGYLVLQPFLSPAV
ZUPT_XANAC      LAFAIAIHNIPEGIAIAVPVYFATRNKFYAVGASLLSGLAEPVGAGIGYLALFSVLSDAV
ZUPT_XANCP      LAFAIAIHNIPEGIAIAVPVYFATRNKFYAFGASLLSGLAEPIGAGIGYLLLSSVLSEAV
ZUPT_STRMU      IVIAIAIHNIPEGIAVSVPIYQATGSKKKAFTYSFLSGLAEPLGAIIGWFLLMPIMNNIV
ZUPT_CLOPE      ITIAIAIHNIPEGISVSVPIFYATGDKKKAFLYSFLSGMSEPIGAIIGYTLLRNIFNDIT
ZUPT_CHLCH      IAVAIAIHNIPEGLAVSAPIFYATQSRKKAFILSFLSGLAEPVGALIGYFLLRSFFSPSL
ZUPT_OCEIH      IAIAVAIHNIPEGIAVSVPIYYATGDRKKAFKYSFLSGLAEPLGAIVAILILMPFLNDLM
ZUPT_COREF      VAVAIAIHNIPEGIAVAVPIREATGSRGKALKWATLSGLAEPAGAVVGFILLMPFLGPEA
ZUPT_CORGL      VAVAIAIHNIPEGIAVAVPLREATGSRRKALGWATLSGLAEPAGALIGFLLLMPFIGPEA
ZUPT_CAMJE      IAIAVAIHNIPEGLAVSLPIYHATGDKKKAFIYSALSGFAEPLGAFVGALILLPFIGDLT
                :..*:*:******:::  *:  ** .:  :.  . :**::*  *. :    *  ...   

ZUPT_SHIF8      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_SHIFL      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_SHISS      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_ECOHS      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_ECOLC      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_ECOLI      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_ECOL5      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_ECO24      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_ECO57      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_ECOL6      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_ECOK1      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_SHIDS      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
ZUPT_SALTI      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG
ZUPT_SALTY      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG
ZUPT_SALPB      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG
ZUPT_SALCH      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG
ZUPT_SALPA      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG
ZUPT_SALAR      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGLSLVILQTIGIG
ZUPT_ENT38      MAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGLSLVLLQTAGFG
ZUPT_NEIMF      FGSVFGVIAGVMVFLALDELLPAAKRYSDGHETVYGLTMGMAVIAVSLVLFHF----
ZUPT_NEIMA      FGSVFGVIAGVMVFLALDELLPAAKRYSDGHETVYGLTMGMAVIAVSLVLFHF----
ZUPT_NEIMB      FGSVFGVIAGVMVFLALDELLPAAKRYSDGHETVYGLTTGMAVIAVSLVLFHF----
ZUPT_XANAC      FGTVFGLISGVMVFLALDELLPAAKRYAQGHETVYGLVSGMGTLAISLVLFRFATP-
ZUPT_XANCP      FGAVFGVIAGVMVFLALDELLPAAKRYAQGHETVYGLVSGMGTLAISLVLFRYAAP-
ZUPT_STRMU      YGAIFSAVAGIMVFISLDELLPAAEEYGKHHLAIYGVISGMLIMAVSLLLFI-----
ZUPT_CLOPE      LGILLSAVAGIMVFISLDELLPTARKYGEHHLAIYGLIAGMVVMAVSLLLFI-----
ZUPT_CHLCH      FGVVFGAVAGIMVYISLDELLPAAEEYGEHHFAIGGVIAGMVVMAISLLLFT-----
ZUPT_OCEIH      FGIIFAMVAGIMVFISLDELLPAARKYDEAHMSMYGVISGMALMAVSLLLLA-----
ZUPT_COREF      MGLSFAAVAGIMVFISLDELLPTAISSGRHHTAIYGLVGGMAVMAVSLLLFI-----
ZUPT_CORGL      LGLCFAAVAGVMVFISVDELLPTAISSGKHHTAIYGLIAGMAVMAISLLLFI-----
ZUPT_CAMJE      LAISFAVIAGIMVFISLDELLPAAKTYDKAHDSLYGLIAGMAIMALSLNLLGQ----
                 .  :. ::*:** :::***:* *      : .  *:  **  :..** ::