CLUSTAL format seed alignment for MF_00719
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
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COBS_FUSNN --------------------------------MKGFLLLLSFMTRIPMPKTDYD-EEKLG
COBS_CLOD6 --------------------------------MKRFILILQFLTRIPIKLNVGF-DDEFY
COBS_CLOAB -----------------------------MAFFRRLILMIQFLTRIPIKYESDITTEDFG
COBS_ACET2 -----------------------------MKYLKRILLMVGFLTRIPVPFKIDGTEEDYG
COBS_CALS4 -----------------------------MEELKALILSIQFMTGIPIPINIDVKEDKIY
COBS_CLOTE -----------------------------MKYIYNFLLMIQFLTRIPVKRSLPCEKEDFR
COBS_LISMO --------------------------------MKTLILLIQFFTRIPLPIQINMDEINLK
COBS_LISMF --------------------------------MKTLILLIQFFTRIPLPVQINMDEINLK
COBS_LISIN --------------------------------MKTLILLIQFFTRIPLPIQINMDEINLK
COBS_LISW6 --------------------------------MKTLILLIQFFTRIPIPIAINMDEVNLK
COBS_CLONN --------------------------------MKNLILMIQFFTRIPINIEIDVKEDSFA
COBS_ALKOO --------------------------------MKSLLLMMTFFTRIPVTYPYDYDEKDFI
COBS_CLOP1 ----------------------------MKIFYKAINMTLSMFTVIPLPK-YEWDDRAAK
COBS_CLOPE ----------------------------MKIFYKAINMTLSMFTVIPSPK-YEWDDRAAK
COBS_CLOPS ----------------------------MKIFYKAINMTLSMFTVIPLPK-YEWDDRAAK
COBS_CLOB8 ----------------------------MKKLYKGFIMALSMFTILPTPY-VEWDDDGVK
COBS_GEOKA ----------------------------MKQAWNGWLLALQLFTTIPIRRSIAWNAAHVR
COBS_GEOTN ----------------------------MRQMWNGWLLALQLFTVIPIRRSIEWNDIHVR
COBS_HALH5 ----------------------------MKHGLNGLLLAFQFLTTVPITRQIPWTARSAR
COBS_ECOLI -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_ECO57 -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_SHIFL -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_SHIF8 -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_ECOHS -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_SHISS -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_ECO24 -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_ECOL5 -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_ECOL6 -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_SHIDS -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_SHIBS -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_ECOLC -------------------------------MSKLFWAMLSFITRLPVPRRWSQGLDFE-
COBS_SALTY -------------------------------MSKLFWAMLAFISRLPVPSRWSQGLDFE-
COBS_SALCH -------------------------------MSKLFWAMLAFISRLPVPSRWSQGLDFE-
COBS_SALTI -------------------------------MSKLFWAMLAFISRLPVPSRWSQGLDFE-
COBS_SALPA -------------------------------MSKLFWAMLAFISRLPVPSRWSQGLDFE-
COBS_SALAR -------------------------------MSKLFWATLSFISRLPVPSRWAQGLDFE-
COBS_CITK8 -------------------------------MSKLFWAMLAFISRLPVPTRWSQGLDFE-
COBS_KLEP7 -------------------------------MIKSFFAALSFISRLPVPARLSQGLEIE-
COBS_ROSS1 --------------MSSEDTTSQRAPRNWWGPFAPIGEALRFLTILPVPGL--PPMSEE-
COBS_CHLCH -------------------------------MLGGLVTALRTLTILPIP-------GKD-
COBS_CHLPM -------------------------------MLSGLVSAIRTLTIFSVP-------GKD-
COBS_CHLTE -------------------------------MLSGLVTALRTLTALPVP-------GRD-
COBS_VIBCH ------------------------MAAILRYQLELFLLAVSFFSRIPV----PVSLPYS-
COBS_VIBC3 ------------------------MAAILRYQLELFLLAVSFFSRIPV----PVSLPYS-
COBS_VIBVY -------------------------MKTWQYQYQLFCLAVSFFSRLPV----PKSTPYS-
COBS_VIBVU -------------------------MKTWQYQYQLFCLAVSFFSRLPV----PKSTPYS-
COBS_VIBPA -----------------MSESKSSRQATLRYQMELFLLAVSFFSRLPV----PSDLPYS-
COBS_PSEA6 ------------------------MTRFLNYQFNLILLAVSFFTRLPV----PTAIDYS-
COBS_SHESW ----------------------MSERESWHKEIDLFLVAMGYFTRIPM----PKWVEVD-
COBS_SHEPC ----------------------MSERESWHKEIDLFLVAMGYFTRIPM----PKWVEVD-
COBS_SHEB8 ----------------------MSERESWHKEIDLFLVAMGYFTRIPM----PKWVEVD-
COBS_SHEB9 ----------------------MSERESWHKEIDLFLVAMGYFTRIPM----PKWVEVD-
COBS_SHEB5 ----------------------MSERESWHKEIDLFLVAMGYFTRIPM----PKWVEAD-
COBS_SHESM ----------------------MSERESWHKEIDLFLVAMGYFTRIPM----PKWVEVD-
COBS_SHESR ----------------------MSERESWHKEIDLFLVAMGYFTRIPM----PKWVEVD-
COBS_SHESA ----------------------MSERESWHKEIDLFLVAMGYFTRIPM----PKWVEVD-
COBS_SHEON ----------------------MSERESWHKEIDLFFVAMGYFTRIPM----PKWVEVD-
COBS_SHEFN ----------------------MSGEIKWLRQLNLFFVAMSFFTRIPV----PSWVVID-
COBS_SHEDO ----------------------MSNEYNWLRQLNLFFVATGFFTRLPT----PSWVIAD-
COBS_SHEPA -------------------------MQAWQQQLNLFFIAMGFFTRIPM----PKWIEVD-
COBS_SHEHH -------------------------MQLWQKQLNLFFIAMGFFTRIPM----PKWIEVD-
COBS_SHEAM -------------------------MSTFKRELELFLLALTFFTRIPV----PVKLDYS-
COBS_AROAE -------------------------MTTMRYQLELFFTALGFFTRLPV----PAWVPWS-
COBS_RALN1 ------------------------MMAALREACRSLWIAIGYFTRIPV----PASVGFS-
COBS_LEPIC -------------------------MNKLQEEWNRFCASWMFNTRLPI----LPFYVYS-
COBS_LEPIN -------------------------MNKLQEEWNRFCASWMFNTRLPI----LPFYVYS-
COBS_POLSJ -------------------------MNPISQFVREYLLAVQFFTRIPVVGRLADWVGYS-
COBS_POLNA ----------------------------MLQFIRHYLLAVQFFTRIPVTGRLADWVGYS-
COBS_ALBFT ----------------------------MSQFIRHYLLSLQFFTRIPVTGRLANWVGFS-
COBS_BRADU ---------------------MIPGTETIRNVIADLRIAASFVTLLPVG---SSKPAAD-
COBS_RHILO -------------------MKLPNLTLSPRQILDDVALCLVFFTRLPLP---DLDFRGR-
COBS_SINMW -------------------------MTEIREFWDDVARSVAFLSRIPVP---DRHFRGH-
COBS_RHIME -------------------------MADIRELWDDVARSVAFLSRIPVP---DRYFHGY-
COBV_SINSX -------------------------MGFVGDFCDDVARSIGFLSRIPMP---ARHFEGY-
COBS_RHIEC --------------------------MKIKDYAVDTARAVAFLSRLPMP---PALFNGY-
COBS_RHIJ3 --------------------------MKIKDYAVDTARAVAFLSRIPMP---QSLFKGY-
COBS_BRUAB --------------------------MQRNGLIGDTIRSLGFLSRLPLP---QGWFDNT-
COBS_BRUSU --------------------------MQRNGLIGDTIRSLGFLSRLPLP---QGWFDNT-
COBS_BRUSI --------------------------MQRNGLIGDTIRSLGFLSRLPLP---QGWFDNT-
COBS_BRUC2 --------------------------MQRNGLIGDTIRSLGFLSRLPLP---QGWFDNT-
COBS_BRUA2 --------------------------MQRNGLIGDTIRSLGFLSRLPLP---QGWFDNT-
COBS_BRUME --------------------------MQRNGLIGDTIRSLGFLSRLPLP---QGWFDNT-
COBS_BRUO2 --------------------------MQRNGLIGDTIRSLGFLSRLPLP---QGWFDNT-
COBS_BRUA4 --------------------------MQRNSLIGDTIRSLGFLSRLPLP---QRWFEDG-
COBS_AZOC5 --------------------------MRHSRILADVGAALRFYSRIPVP---AGAAEDAF
COBS_PSEAE ----------------------------MREALRSLLVALQFLTRLPVRLSAMPTPEQF-
COBS_PSEAB ----------------------------MREALRSLLVALQFLTRLPVRLSAMPTPEQF-
COBS_PSEA7 ----------------------------MREALQSLLVALQFLTRLPVRLSAMPTPEQF-
COBS_PSEF5 --------------------------------MLPFWIALQFLSSLPVRLPGMPRPEEL-
COBS_PSEPF --------------------------------MLPLWIALQFLGSLPIRLPGMPTPEQL-
COBS_PSE14 --------------------------------MLPFWIALQFLGSLPIRLPGMPRPEEL-
COBS_PSEU2 --------------------------------MLPFWIALQFLGSLPIRLPGMPSPEEL-
COBS_PSESM --------------------------------MLPFWIALQFLGSLPIRLPGMPRPAEL-
COBS_PSEPK --------------------------------MLPFWIALQFLSSLPVSLPGMPAPREV-
COBS_PSEP1 --------------------------------MLPFWIALQFLSSLPVSLPGMPAPREV-
COBS_PSEPG --------------------------------MLPFLIALQFLSSLPVSLPGMPAAREV-
COBS_PSEE4 --------------------------------MLPFWIALQFLSSLPVRLPGMPTPNEM-
COBS_STUS1 --------------------------------MLPLLIALQFLTSLPIRLPAMPTPRQQ-
COBS_PSEMY --------------------------------MIAPRIALQFLTRLPVSLPGMPTPEQI-
COBS_ALKEH ----------------------------MTTAVRGLLLALAFLTRLPVWWLGPPRREDH-
COBS_SYNP6 -------------------------MIRQLW--TELNAAILFYTVLPLPQRWPTQFAGM-
COBS_SYNE7 -------------------------MIRQLW--TELNAAILFYTVLPLPQRWPTQFAGM-
COBS_NOSS1 -------------------------MVKLLL--LNLLASIIFYTNIPLPYINGLDFQRV-
COBS_TRIV2 -------------------------MVKLLL--LNLLASIIFYTSIPLPYIKGLDFQKV-
COBS_THEVB --------------------------MKSLW--QEWLGAIAFYTCLPISPRWPIQLAGA-
COBS_SYNY3 --------------------MEWWRRWYFLWGGDSVGAAILFYTRLPWPPSWPVNFDRI-
COBS_PROM3 --------------------------MRAPLWLRDLAGAWIFYSVLPAWPGLKPRFERI-
COBS_PROMM --------------------------MRAPLWLRDLAGAWIFYSVLPAWPGLKPRFERI-
COBS_PROMA --------------------------MSSPNWLKDLTGAWLFYTVFPKLTRINPRFERI-
COBS_MYCTU -------------------------------MMRSLATAFAFATVIPTPG--SATTPMGR
COBS_MYCTA -------------------------------MMRSLATAFAFATVIPTPG--SATTPMGR
COBS_MYCBO -------------------------------MMRSLATAFAFATVIPTPG--SATTPMGR
COBS_MYCBP -------------------------------MMRSLATAFAFATVIPTPG--SATTPMGR
COBS_MYCUA -------------------------------MIRSLATALSFGTVIPVPA--SVAAPMGR
COBS_MYCA1 -------------------------------MMRSLATAFAFGTVLPMPA--GGRGPMGR
COBS_MYCPA -------------------------------MMRSLATAFAFGTVLPVPA--GGRGPMGR
COBS_MYCGI -------------------------------MTRSLAGAFAFATVMPVPS--RRAAIAGR
COBS_MYCVP -------------------------------MISSLTGAFAFATVLPTPT--RATAMVGR
COBS_MYCS2 -------------------------------MIRSLAGAFAFGTVLPV----RASAGVGR
COBS_MYCSK -------------------------------MIGSLAGAFAFGTVLPVPA--GSTATLGR
COBS_MYCSS -------------------------------MIGSLAGAFAFGTVLPVPA--GSTATLGR
COBS_MYCSJ -------------------------------MIGSLAGAFAFGTVLPVPT--GSTATLGR
COBS_FRACC -------------------------------MMLEARTAFTLLTVLPLRGPEHTDRRLAG
COBS_CORGL ---------MSGKAGFTPEDPEDSDNRHGNPLFEGIFTALNWMTVLPVPGASVFDRTTGA
COBS_CORGB ---------MSGKAGFTPEDPEDSDNRHGSPLFEGIFTALNWMTVLPVPGASVFDRTTGA
COBS_COREF ---------MSGKAHVT-------DGDHGPALTEGVTTALNWLSVLPIRGATTFDRITGA
COBS_METAC ----------------------------MNSYLLAFKSGFGFLTTIPVGISMEGIDELMK
COBS_METMA ----------------------------MNSYLLAFKSGFGFLSTIPVGITMEGIDELMK
COBS_METBF ----------------------------MNSYLLAFKSGFGFLSTIPVGISMEGIDELMK
COBS_METBU ----------------------------MSGFLLALRTTFGFLSTIPVGMSMEGLDELVK
COBS_PYRAB -----------------------------------MRNILPFLTRIP----VKGDFEKAR
COBS_THEKO -----------------------------------MRNILPFLTRIP----VKGDFEKAR
COBS_PYRHO -----------------------------------MKNILPFLTRIP----IKGDFEKAR
COBS_PYRFU -----------------------------------MKNLIQFMTRVP----IKGDFEKAR
COBS2_ARCFU -------------------------------MIKAIRSAISFLTTLP----LGGDVEELR
COBS1_ARCFU ------------------------------MALDLLRSSLGFLTTLP----VKGDVDVLR
COBS_THEAC --------------------------------MKGLRSAFSFFTIIP------IKSELDE
COBS_THEVO ------------------------------MMISGLRSSFSFFTLVP------SRQKDIG
COBS_PICTO --------------------------------MQGLKSAISFFTIIP------VKADLNK
COBS_SULTO -----------------------------MKIFKKIASQISFFTIIP--STKATLEEVAS
COBS_SULAC ----------------------------MGRILKAILGQLSFFTIIP--SPSASLEEIAE
COBS_SACS2 ------------------------------MHLKEILAQFSFFTAIPV-KSSASLEEIAE
COBS_PYRCJ --------------------------------MQCLRALLSFFTIIP----AGVAKLDFK
COBS_PYRAE --------------------------------MRCLKSLLAFFTAFP----IGGAELSFK
COBS_PYRIL --------------------------------MRCLKAVVAFFTALP----VGGAELDFS
COBS_METJA ---------------------------MGITMFKEFKALLSFFTRIPIYVEDFDFENIAN
COBS_METTH -----------------------------MNVTGKLRGLISFSTVLPLKSEASIEDIASL
COBS_CARHZ -------------------------------MLTTFLLGLTFFTRIPVPGKLNFSEEKFN
COBS_DEIRA MVQPSPAPVVTITPAPAPAAPSHPHGWKRKQEFKALHLALAFLTTLPLPHVRDVQPGDFA
COBS_METKA ------------------------------MIRVEFLKVFRFLTVLPIGEHPKSPREIGE
..
COBS_FUSNN ------KSMKYFPVVGIIVGFILLFFCIIFNFILKNISYSAVLPLMIIVVILTDLITTGA
COBS_CLOD6 ------KSIVYFPLVGFVIGILSYLIGWISMLLFEPFIAS-------IIITLAGVLITGG
COBS_CLOAB ------KALALVPIVGLIIGGIMGVTYMLLVKVFFYKISA-------VLVLIEYIFLTGG
COBS_ACET2 ------KGLVFAPVVGLLIGGILTILFYILKRFFPPGVTG-------ILLIAAYIMLTGG
COBS_CALS4 ------KIASYFPVVGLLIGGILYIAYLLLKDLFSREIVM-------TFLVAFSYILTRG
COBS_CLOTE ------RGAAMLPLIGLIVGCIQWVVFYILSKIFPANITA-------IFIILVGMVLIGG
COBS_LISMO ------KGSALLPFVGVIIGAWNWLIFTLVALVMPLPVAI-------IAGLFAEVIITGG
COBS_LISMF ------KGSALLPFVGVIIGAWNWLIFTLVALLMPLPVAI-------IAGLFAEIIITGG
COBS_LISIN ------KGSALLPLVGVVIGAWNWLVFSLVALVMPLPVAI-------IAGLFAEIIITGG
COBS_LISW6 ------KGSALLPFVGLIIGAWNWLVFTLVALVMPLPVAI-------IAGLFAEIIITGG
COBS_CLONN ------KGISYLPLVGLIIGGFNAIVYFVSSKFILGTLPI-------VLALLANTIITGA
COBS_ALKOO ------KGVKFLPVIGLLIGILMYLP-TLLAPYIHRPIII-------VSIWALYFLITGG
COBS_CLOP1 ------HIMKLYPFIGLIIGALWYLSFFVLSK-LNVPIML-----MAALILTVPYILTGF
COBS_CLOPE ------HIMKLYPFIGLIIGALWYLSFFVLSK-LNVPIML-----MAALILTVPYILTGF
COBS_CLOPS ------HIMKLYPFIGLIIGILWYLSFFVLSK-LNVPIML-----MAALILTVPYILTGF
COBS_CLOB8 ------NMMKFYPLIGLIIGVLWSIIYYLASI-LNASIIL-----KSSIITIVPFIITGM
COBS_GEOKA ------WLVRCMPLAGALIGALSAGVYALFSTFSFSSPLV-----WALLLLWLGIWMAGG
COBS_GEOTN ------WLVRSMPLAGAAIGALAAGTYALCSMFSFGTPLF-----LALFLLWLGIWLAGG
COBS_HALH5 ------WSIVCYPLTGLVLGGLLVSLYLLLS--PFLSPLV-----LAALLVTLSIFYSGG
COBS_ECOLI ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGA-------PLAALFSVLVLVLMTGG
COBS_ECO57 ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGA-------PLAALFSVLVLVLMTGG
COBS_SHIFL ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGA-------PLAALFSVLVLALMTGE
COBS_SHIF8 ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGA-------PLAALFSVLVLALMTGE
COBS_ECOHS ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGV-------PLAALFSVLVLALMTGG
COBS_SHISS ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGV-------PLAALFSVLVLALMTGG
COBS_ECO24 ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGV-------PLAALFSVLVLALMTGG
COBS_ECOL5 ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGV-------PLAALFSVLVLALMTGG
COBS_ECOL6 ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGV-------PLAALFSVLVLALMTGG
COBS_SHIDS ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGV-------PLAALFSVLVLALMTGG
COBS_SHIBS ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGV-------PLAALFSVLVLALMTGG
COBS_ECOLC ---HYSRGIITFPLIGLLLGAISGLVFMVLQAWCGV-------PLAALFSVLVLALMTGG
COBS_SALTY ---QYSRGIVMFPFIGLILGGVSGLIFILLQPWCGI-------PLAALFCILALALLTGG
COBS_SALCH ---QYSRGIVMFPFIGLILGGVSGLIFILLQSWCGI-------PLAALFCILALALLTGG
COBS_SALTI ---QYSRGIVMFPFIGLILGGISGLIFILLQPWCGI-------PLAALFCILALALLTGG
COBS_SALPA ---QYSRGIVMFPFIGLILGGISGLIFILLQSWCGI-------PLAALFCILALALLTGG
COBS_SALAR ---QYSRGIVMFPLIGAILGGLSGLIFILLQPWCGI-------PLAALFCILALALLTGG
COBS_CITK8 ---EYSRGIVTFPLIGMLLGAIGGLVFVALQSWCGI-------PLAALFCVLTLALLTGG
COBS_KLEP7 ---QYQRSIVTFPLVGLLLGAIAGAVALLLQPWCGV-------PLAALFGVLALALLTGG
COBS_ROSS1 ---AIPQSIRYFPIAGLVIGGILAAVGWGAGVLWNE-------TVRAVVLVVAWGVLTAG
COBS_CHLCH -AVTFSHSLYWFPFVGLLLGALLAALGYVGSLSGWH-------EFAALLVVLGGIVLTRG
COBS_CHLPM -AENFSSSLYWFPVVGAFLGTLLAACAWLPLSIGWS-------ELASAVVVVGGFIVSRG
COBS_CHLTE -AERFSSSLYWFPVVGLVIGGIVVLLARAGMGVGWP-------ELAAVLALLGGLILTRG
COBS_VIBCH -SERMNQAGRYFALVGLLLGAICALVYSLATQLFS-------TNISVFLTMVLSLLLTGA
COBS_VIBC3 -SERMNQAGRYFALVGLLLGAICALVYSLATQLFS-------TNISVFLTMVLSLLLTGA
COBS_VIBVY -DERMNQAGRYFALVGTLLGLLCVLVYAFASLFFP-------YQVAIVLMMAFSLLLTGA
COBS_VIBVU -DERMNQAGRYFALVGTLLGLLCVLVYAFASLFFP-------YQVAIVLMMAFSLLLTGA
COBS_VIBPA -EERMNQAGRYFALVGVILGVLCALVFYFTQLIFP-------DSVAIVLTMAFSLLLTGA
COBS_PSEA6 -PQKLHQAGRYFPLVGWLLAALLSAFYCFMLPYLG-------REPTVCLLIIFSLMLTGA
COBS_SHESW -SDKLNKASRYFGLVGLLIGLLSAIVFWLTQNWLP-------AGVSVLLAMLVGVLLTGG
COBS_SHEPC -SDKLNKASRYFGLVGLLIGLLSAIVFWLTQNWLP-------AGVSVLLAMLVGVLLTGG
COBS_SHEB8 -SDKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLP-------AGVSVLLAMLVGVLLTGG
COBS_SHEB9 -SDKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLP-------AGVSVLLAMLVGVLLTGG
COBS_SHEB5 -SDKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLP-------AGVSVLLAMLVGVLLTGG
COBS_SHESM -ADKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLP-------AGVSVLLSMVTGVLLTGG
COBS_SHESR -ADKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLP-------AGVSVLLSMVTGVLLTGG
COBS_SHESA -ADKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLP-------AGVSVLLSMVTGVLLTGG
COBS_SHEON -ADKLNKASRYFGLVGLLVGLLSAIIFWLTQNWLP-------AGVSVLLSMLTGILLTGG
COBS_SHEFN -SDKLNKASRYFGLVGLLIGLICALVFWLAQLILP-------ASIAILLAMVAGVLVTGA
COBS_SHEDO -DNELKKSSRYFGLVGLLIGLICALVYWFTQQWLP-------TSVAVLLAMVAGVLVTGG
COBS_SHEPA -ADKLNKASRYFGLVGLLVGAISALVYTLMLYWVS-------PSIAIVLAMITSVLVTGG
COBS_SHEHH -ADKLNKASRYFGLVGLLVGAISAAVYSLMLYWVS-------PSVAIVFAMITSVLVTGG
COBS_SHEAM -GEGLNRASRYFGLVGTLVGLIAALVFYLTQFIFP-------ASVAVVLAMIATVLLTGG
COBS_AROAE -PERLNHAARFFPLVGWVVGAIGAASYLAFVQLLP-------PALAVLLSMAVTIRATGA
COBS_RALN1 -QDGLNRAARFFPLVGWLVGAAGALAYWLASRTVPA------PGVAVAASMAATLLLTGA
COBS_LEPIC -ESTLSRSSRYFPLIGWIVSAGTSYSTYFLSWILP-------IEISIILGMILSVLITGG
COBS_LEPIN -ESTLSRSSRYFPLIGWIVSAGTSYSTYFLSWILP-------IEISIILGMILSVLITGG
COBS_POLSJ -PELLRASAGHFPGVGILVGVMAALVYGLIQALLPNTPFT--PLVAAVLSTAATVLLTGG
COBS_POLNA -PGMLRASAVHFPGIGVVVGGAAAAMFALLQLLLPDTTFT--PLVAAAFSTVATVWLTGG
COBS_ALBFT -PAMLRASAGHFPGVGVLVGALVAAFTALLLFVLPRTGST--PLVAAALGTALGVLLTGA
COBS_BRADU --GAIARATWALPVAGLLVGLAGALVYKISSRLGLT------PNLAALLALATTALITGA
COBS_RHILO --G-LAAAIWAAPVAGLLVGLIGAIVFATAERFGLA------MGPAAALALVATVIATGC
COBS_SINMW -DGGLGRAVRAFPLAGILIALPAAVTAVLLGAIHAS------SLFTAFLIVAAQATVTGA
COBS_RHIME -DGGLGRAVRAFPLAAILITLPAAAIAFILGALHAS------SLFSAFLVVAVQAMVTGA
COBV_SINSX -DGRLSRAVRAFPFAGLAIALPSAAVAMALMALQVS------SLFAAFVVVAIQALVTGA
COBS_RHIEC -DGRLNRLVRAFPFAGLLIGFVPAVTLLLLLSLRTD------PLVAALVALSVQALVTGA
COBS_RHIJ3 -DGRLGRLVRAFPFAGIVIGFIPALALLLLLGLRAD------PLMAALIALSIQVLVTGA
COBS_BRUAB -DDSLPRNARAFPLAGGILGLLAGVALLIANAISLP------PLAAALIAIGALAAMTGA
COBS_BRUSU -DDSLPRNARAFPLAGGILGLLAGVALLIANAISLP------PLAAALIAIGALAAMTGA
COBS_BRUSI -DDSLPRNARAFPLAGGILGLLAGVALLIANAISLP------PLAAALIAIGALAAMTGA
COBS_BRUC2 -DDSLPRNARAFPLAGGILGLLAGVALLIANAISLP------PLAAALIAIGALAAMTGA
COBS_BRUA2 -DDSLPRNARAFPLAGGILGLLAGVALLIANAISLP------PLAAALIAIGALAAMTGA
COBS_BRUME -DDSLPRNARAFPLAGGILGLLAGVALLIANAISLP------PLAAALIAIGALAAMTGA
COBS_BRUO2 -DDSLPRNARAFPLAGGILGLLAGVALLIANAISLP------PLAAALIAIGALAAMTGA
COBS_BRUA4 -DDSLPRNARAFPLAGAVLGLLAGAVLFMAYKVNLP------PLACAMLAIGALAAMTGA
COBS_AZOC5 APPDLKRIAYAVPLAGAAIGLAGAAILIGAHALGLP------NLVAAILAVLTCVLLTGA
COBS_PSEAE -----GRAVLCYPLVGVLIGVVLYAAARSLD---GTPPL-----LQAALLLSLWVALSGA
COBS_PSEAB -----GRAVLCYPLVGVLIGVVLYAAARSLD---GTPPL-----LQAALLLSLWVALSGA
COBS_PSEA7 -----GRAVLCYPLVGVLIGVVLYGAARSLD---GTPPL-----LQAALLLSLWVALSGA
COBS_PSEF5 -----GRSLLFYPLVGLLFGVLLWVLNAMLG---GVPLL-----LHAALLLTAWVLLSGG
COBS_PSEPF -----GRSLLFYPLVGLLFGVILWALNIALA---GTPLL-----LHAALLLAVWVLLSGA
COBS_PSE14 -----GRSLLFYPLVGVVFGMLLLGFSALLS---GTPLM-----LHAALVLSAWVLLSGG
COBS_PSEU2 -----GRSLLFYPLVGAVFGTLLLGFNTLLS---GAPLM-----LHAALVLTAWVLLSGG
COBS_PSESM -----GRSLLFYPLVGVVFGTLLLGFNALLS---GAPLL-----LHAALLLSAWVLLSGG
COBS_PSEPK -----GRSLLYYPLVGLLFGLLLWLASHLLQ---GTPSP-----LHAALLLTLWVLLSGA
COBS_PSEP1 -----GRSLLYYPLVGLLFGLLLWLASHLLQ---GTPSP-----LHAALLLTLWVLLSGA
COBS_PSEPG -----GRSLLYYPLVGLLFGLLLWLASHLLQ---GTPAP-----LHAALLLTAWVLLSGA
COBS_PSEE4 -----GRSLLFYPVVGLLFGLLLWLASHLLQ---GAPAP-----LHAALLLALWVLLSGA
COBS_STUS1 -----GRSLLHYPAVGLFLGALLWLAALLLE---GASPL-----LQAALLLALWVALTGA
COBS_PSEMY -----GRSLLWYPAVGLLLGLLLWLAHLLLG---QTPDV-----LQAAIILALWVGLSGG
COBS_ALKEH -----AASLPAYPVVGLILGILLLALYALLQWFFPDQFV-----VQAALLVAAWALVTGL
COBS_SYNP6 --------SRWAPIVGLILGLILAVSDRLLAVGQFP------LPLRSLLIVLLAIALTGG
COBS_SYNE7 --------SRWAPIVGLILGLILAVSDRLLAVGQFP------LPLRSLLIVLLAIALTGG
COBS_NOSS1 --------ARLVPTVGLIIGGILGLFDGGMNYLGMP------VLTRSALVVVLWIFITGG
COBS_TRIV2 --------ARLVPMVGLIIGVILGLLDGGMNYLGMP------VLTRSALVVALWIFITGG
COBS_THEVB --------AKWCPWVGLVLGGMLWGVQWLLDFLQVP------SPVASAVLVALWLALTGG
COBS_SYNY3 --------ARWITLMGLLLSLILLALDRGLHWLGMD------NLLQSAVVVSLWLALTGG
COBS_PROM3 --------ARFAPWIGLVLGGLQSFLWLVLIRADWP------TSAVALLVIGLGAWLSGG
COBS_PROMM --------ARFAPWIGLVLGGLQSFLWLVLIRADWP------TSAVTLLVIGLGAWLSGG
COBS_PROMA --------ARFSPLIGVLIGVLQVSVLILLLQLQWP------NESMPFIAIALGLWITGG
COBS_MYCTU ------GPMTALPVVGAALGALAAAIAWAGAQVFGP-----SSPLSGMLTVAVLLVVTRG
COBS_MYCTA ------GPMTALPVVGAALGALAAAIAWAGAQVFGP-----SSPLSGMLTVAVLLVVTRG
COBS_MYCBO ------GPMTALPVVGAALGALAAAIAWAGAQVFGP-----SSPLSGMLTVAVLLVVTRG
COBS_MYCBP ------GPMTALPVVGAALGALAAAIAWAGAQVFGP-----SSPLSGMLTVAVLLVVTRG
COBS_MYCUA ------GAMTALPVVGVVLGGLAAGVTWSASLVFGP-----VSPLPGLLAVAVLLLATRG
COBS_MYCA1 ------GAMTALPVVGLALGALAAAVAWGGTVVFGR-----SSPLGGLLAVAALLLITRG
COBS_MYCPA ------GAMTALPVVGLALGALAAAVAWGGAVVFGR-----SSPLGGLLAVAALLLITRG
COBS_MYCGI ------GVLTALPVVGLVLGSAAAAVCWLGTRAFGS-----GSVLAGALTVAVLLLATRG
COBS_MYCVP ------GVLTALPVAGAALGVLAAGVLWAGSWAFGD-----GSALAGVLTVAVLLLATRG
COBS_MYCS2 ------GALTALPFVGLALGALAAAVVWAGGWAFAA-----GSPLPGVLAVAVLLLATRG
COBS_MYCSK ------GVMTALPGVGIVLGAVAAAVLWAGSWAFGP-----HSALAGLLAVAVLLLATRG
COBS_MYCSS ------GVMTALPGVGIVLGAVAAAVLWAGSWAFGP-----HSALAGLLAVAVLLLATRG
COBS_MYCSJ ------GVMTALPGVGIVLGAVAAAVLWAGSWAFGP-----HSALAGLLAVAVLLLATRG
COBS_FRACC ------RAMALAPFVGLALGLLAGSAVFATRIVTAVPGQRAQTLLPAVVGVTVLALVTRG
COBS_CORGL ------RVMASLPFVGFVFGMFTAIIMWAIGPISGVIH--VDGLLVAVLIVAFWELLNRF
COBS_CORGB ------RVMASLPFVGFVFGMFTAIIMWAIGPISGVIH--VDGLLVAVLIVAFWELLNRF
COBS_COREF ------RVMASLPVVGVVFGVLTAVLL----GLLGVLG--VTPLLTAVLVVIMWELLNRM
COBS_METAC ------KIYFYPVVGAVLGLLIGAIAYIGQLIFPDPVL--------AALIMGSVYYFTGF
COBS_METMA ------KIFFYPVVGAVLGLLIGIVAYAGQLVFPGPVL--------AALIMGFVYYITGF
COBS_METBF ------KIYFYPVVGAVLGLLIGAVAFIGQVIFPGPVL--------AALLMGFIYYITGF
COBS_METBU ------RSYLQTFAGIVLGSMIGIFAYLTESFLPSTIS--------AVLIMVFIYYITGL
COBS_PYRAB ------NELWAFPLVSLVSSIIPIAILYLRIPLANVLA--------LLSLYFVI----GL
COBS_THEKO ------NELWAFPLVALVSSALPTLILYLGLPLSNLLA--------VLALYWTI----GL
COBS_PYRHO ------RELWAFPLVSVFTSPLPALILYLKVPLASILA--------LLSLYFTI----GL
COBS_PYRFU ------EEVWMLPLLTPLTAFIPSLILYLNIPLKNVLS--------ILSLYWVI----GL
COBS2_ARCFU ------KNLWLFPYAAILIALIVSVPHFIRNFVDIRFL--------ALVLYLGAE---GI
COBS1_ARCFU ------RNLWVFSFVGIFIGSVISIPAVL----GFWFL--------CVLLYVAIE---GV
COBS_THEAC ------HLIAYVPLVALFDAALAASLYVAIYGISKLLA--------SFISVSAIYIVNGL
COBS_THEVO ------NPITFLPLVVTVGALIGDSILYITWQFSHLIA--------SFLSISSIIIYNGL
COBS_PICTO ------NIVFFFTITGAITGLMAASIFYLTSFINQLLA--------SVASVSFLIIIYGF
COBS_SULTO ------ASFISPIIIGVITALIDYSVVFVTSKFLGNLA--------FLLLLPTVEIIRGF
COBS_SULAC ------FSFISPLMVGIITGIIDWFVVLLGIRLIGSLG--------ALLLIPTVEIIRGF
COBS_SACS2 ------SSYISPIIVGISLGLIESVAYLILYRILGELT--------GIVLLGIIELLRGF
COBS_PYRCJ ------CAWALPYVVPPLVAGPAAAALWLGASPHVAYL--------LLLLMTGL------
COBS_PYRAE ------CVWALPYVAAPIIAAIPTTLLYLGASPAIAYI--------ALLAATGL------
COBS_PYRIL ------CIWATPYLAGLMVGGAGGAVYFLTHSPAAAYA--------ALLLATGL------
COBS_METJA -------YFYLIILIGYVFGIFSLILGYIFSFLLPNF-------LSAVLILFFIEYLNGF
COBS_METTH --------TLHWPLVGALIGVAVGSAGVAASLVFPG-------AVVACVAYGFAIWFTGF
COBS_CARHZ ------RAPIFLPAYGLVTGGILALIIELFGRSFPGF-------FWAGVIIAGQIYLSGA
COBS_DEIRA ------RASAYYPLAGYAVGGLVAGLLYLNVPLPPG--------VVAALGVGLWLGLTGM
COBS_METKA ------QAWLGLPAVGLVSGLLAGVVAWAFAGTPVR----------GCLVVLTLLVLEGA
COBS_FUSNN LHLDGLADTFDGIFSYR-S-KHKMLEIMKDSRLGSNGALALILYFLLKFILLFSLTIESR
COBS_CLOD6 LHIDGLGDTFDAIYSYR-D-KEKMLEIMKDSRLGTNSLLAIMFVLLLKVGFVYDIISNN-
COBS_CLOAB IHLDGLGDTFDGVFSNR-P-KERILEIMRDSRVGTNAVLAVISVIILNYVILTEIDPAY-
COBS_ACET2 LHLDGLGDTFDGIFSNR-S-REKMLEIMRDSRIGTNAVLAVICVVILNYALLSSIPLSG-
COBS_CALS4 MHIDGLADTFDGLFSNK-D-REKIIEIMKDSRLGTNGVLALVFMVILKILFLSDIRQSL-
COBS_CLOTE LHQDGLGDIFDGFFSFKGD-KEKIIEIMKDSRVGTFAVLALIFDILIKYSALSFIIENN-
COBS_LISMO FHVDALADTADGLFSSR-K-RERMLEIMKDSRVGANGVIAICFYFLFYGALFLSVTDTQQ
COBS_LISMF FHVDALADTADGLFSSR-K-RERMLEIMKDSRVGANGVIAICFYFLFYGSLFLSVPDTQQ
COBS_LISIN FHVDALADTADGLFSSR-K-KERMLEIMKDSRVGANGVIAICFYFLFYGALFLSVPNIQQ
COBS_LISW6 FHVDALADTADGLFSSR-K-KERMLEIMKDSRVGANGVIAICFYFLFYGALFLSVPSAYE
COBS_CLONN FHIDGLADTCDGIFSSR-K-KERMLEIMKDSRVGTNGAIAIVFDFMLRYAVLNSLNKKYI
COBS_ALKOO LHIDGLADTFDGIFSYR-S-KEEMLRIMKDSRIGAFGVLGILWLLILNLTLAYYTENM--
COBS_CLOP1 LHLDGFMDVSDALLSRR-D-KETKLRILKDSTVGAFSVISVVLLLLVEFAGMFTVLNKNL
COBS_CLOPE LHLDGFMDVSDALLSRR-D-KETKLRILKDSTVGAFSVISVVLLLLVEFAGMFTVLNKNL
COBS_CLOPS LHLDGFMDVSDALLSRR-D-KETKLRILKDSTVGAFSVISVVLLLLVEFAGIFTVLNKNL
COBS_CLOB8 LHLDGFMDVCDAILSRR-S-KEEKLRILKDSATGAFAVIPLVILFFLQFGGVYSILEKNS
COBS_GEOKA MHADGFMDVSDAFFSYR-D-VKRRQEIMSDPRVGAFAVLSLICLLSFRWLFLYESLQTGI
COBS_GEOTN LHADGWMDVSDAFFSYR-D-AKRRQQIMSDSRVGAFAVLSLACLLSFRWLFLYETIKAEI
COBS_HALH5 LHLDGWMDVSDAFLSRR-D-RETKLIILKDSRVGAFAVMTTILLIGWKVLLLMELI--AL
COBS_ECOLI FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_ECO57 FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_SHIFL FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_SHIF8 FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_ECOHS FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_SHISS FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_ECO24 FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_ECOL5 FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_ECOL6 FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_SHIDS FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_SHIBS FHLDGLADTCDGVFSAR-S-RDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_ECOLC FHLDGLADTCDGVFSAR-S-RDCMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGE
COBS_SALTY FHLDGLADTCDGIFSAR-R-RERMLEIMRDSRLGTHGGLALIFVLLAKILVVSELALRGT
COBS_SALCH FHLDGLADTCDGIFSAR-R-RERMLEIMRDSRLGTHGGLALIFVLLTKILVVSELALRGT
COBS_SALTI FHLDGLADTCDGIFSAR-R-RERMLEIMRDSRLGTHGGLALIFVLLAKILVVSELALRGT
COBS_SALPA FHLDGLADTCDGIFSAR-R-RERMLEIMRDSRLGTHGGLALIFVLLAKILVVSELALRGT
COBS_SALAR FHLDGLADTCDGIFSAR-R-RERMLEIMRDSRLGTHGGLALIFVLLAKILVVSELALRGT
COBS_CITK8 FHLDGLADTCDGIFSAR-R-RERMLEIMRDSRLGTHGGLALIFVLLAKVLVISELALRGT
COBS_KLEP7 FHLDGLADTCDGIFSAR-T-RDRMLEIMRDSRLGTHGGLALIFVLVAKVLVVGELLLRDI
COBS_ROSS1 MHLDGLSDTFDGVMSWR-S-RERKLEIMRDSRIGVMGALALAAVLGLKAAF---LAGAGD
COBS_CHLCH MHADGLADVADGFWGGR-S-KEAALRIMKDPTVGSFGALALSGVMLLKWVAVVRLLSFGL
COBS_CHLPM MHADGLADMADGFWGGG-D-RERTLSIMKDPTVGSFGALALLSLMLLKWVAILRLTEHGA
COBS_CHLTE LHADGLADLADGFFGGR-T-REAALRIMKDPNVGSFGSLALIGVMLFKWICLLELARAEA
COBS_VIBCH FHEDGLADMADGVGGGM-T-AERRLEIMKDSRIGTYGSSALIMVLLGKYLLLTELADLT-
COBS_VIBC3 FHEDGLADMADGVGGGM-T-AERRLEIMKDSRIGTYGSSALIMVLLGKYLLLTELADLT-
COBS_VIBVY FHEDGLTDMADGIGGGM-T-LDKRLTIMKDSRIGTYGSATLTMALIGKFVFLTTLARQP-
COBS_VIBVU FHEDGLTDMADGIGGGM-T-LDKRLTIMKDSRIGTYGSATLTMALIGKFVFLTTLARQP-
COBS_VIBPA FHEDGLTDMADGIGGGM-T-VERRLSIMKDSRIGTYGAATLVMALLAKFVLWSELVHLP-
COBS_PSEA6 IHEDGLADTADGFWGGQ-S-ITRKLTIMKDSQIGTYGTCALICALLSKFILLSSLAADQ-
COBS_SHESW FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGAIALILALLLKWQLLVELALYDP
COBS_SHEPC FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGAIALILALLLKWQLLVELALYDP
COBS_SHEB8 FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGALALILALLLKWQLLVELALYDP
COBS_SHEB9 FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGALALMLALLLKWQLLVELALYDP
COBS_SHEB5 FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGALALMLALLLKWQLLVELALYDP
COBS_SHESM FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGALALMLVLMLKWQLLVELALYDP
COBS_SHESR FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGALALMLVLMLKWQLLVELALYDP
COBS_SHESA FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGALALMLVLMLKWQLLVELALYDP
COBS_SHEON FHEDGLADTFDGFGGGW-T-AEDKLRIMKDSRLGSYGALALIMVLLLKWQLLVELALYDP
COBS_SHEFN FHEDGLADTADGFGGGW-T-VEDKLRIMKDSRLGSYGALSLGLVLLLKWQLLVELALYSP
COBS_SHEDO FHEDGLADTADGFLGGK-T-FEDKLRIMKDNHLGSYGAIVLALILLLRWQLLVELALFSP
COBS_SHEPA FHEDGLADTADGLGGGW-T-VEAKLNIMKDSRLGSYGALALVLALLLKWQLLTELALFDP
COBS_SHEHH FHEDGLADTADGLGGGW-T-VEAKLNIMKDSRLGSYGALALVLALLLKWQLLTELALFDP
COBS_SHEAM FHEDGLADTADGFGGAF-E-RERKLEIMKDSRVGSYGSLALMLALLLKFQLLSELALYSV
COBS_AROAE FHEDGWADACDGLGGGW-D-RLQVLTIMKDSRIGSYGTAGLVLMLLAKAAALVELAAHGN
COBS_RALN1 FHEDGLADCADGFGGGY-T-AEDRLRIMRDSRIGAFGAIAVCMALLLKWQLLMAMAAQHA
COBS_LEPIC FHEDGLADVCDAFGGGW-S-KEKILEIMKDSRIGTFGSIGLILSLGLKYLLLVNLFKISP
COBS_LEPIN FHEDGLADVCDAFGGGW-S-KEKILEIMKDSRIGTFGSIGLILSLGLKYLLLVNLFKISP
COBS_POLSJ FHEDGLADVADGLGGSQ-D-RERALEIMKDSRVGAFGAMALMLALLGKTALLAMLGSVDV
COBS_POLNA FHEDGLADVADGLGGSY-D-RERALEIMKDSRVGAFGAMALVLALLCKVALLALLGSVEA
COBS_ALBFT FHEDGLADVFDGLGGSA-E-RERALVIMKDSRVGAFGAIAVMLALLCKVALLALLGAVSA
COBS_BRADU LHEDGLADTADGLGGGR-T-RERKLEIMRDSRIGTYGVCALILSFGLRWSALAA---IAN
COBS_RHILO LHEDGLSDVADGFGGGK-S-RGRKLDIMRDSRIGAYGAMALALSLLIRWNVLSE---LVD
COBS_SINMW LHEDGLADTADGFGGGR-D-RESALEIMKDSRIGTYGAVALILSFGIRVSALAAFLPLLT
COBS_RHIME LHEDGLGDTADGFGGGR-D-RESALEIMKDSRIGTYGAVALILSFGLRVSALAAFLPLLT
COBV_SINSX LHEDGLGDTADGFGGGR-D-REAALAIMKDSRIGTYAAVALILSFGLRVSAFASILPLFS
COBS_RHIEC LHEDGLADTADGIGGGS-S-REQSLIIMKDSRIGTYGAIALILSFAIRAAALAAIIRHSS
COBS_RHIJ3 LHEDGLADTADGIGGGK-S-REQSLLIMKDSRIGTYGAIALILSLAIRAAALAVIARHSS
COBS_BRUAB LHEDGLGDTADGFFGAS-T-PDRRLDIMKDSRIGTFAALTLVIWTGVKASLLMAIIARAG
COBS_BRUSU LHEDGLGDTADGFFGAS-T-PDRRLDIMKDSRIGTFAALTLVIWTGVKASLLMAIIARAG
COBS_BRUSI LHEDGLGDTADGFFGAS-T-PDRRLDIMKDSRIGTFAALTLVIWTGVKASLLMAIIARAG
COBS_BRUC2 LHEDGLGDTADGFFGAS-T-PDRRLDIMKDSRIGTFAALTLVIWTGVKASLLMAIIARAG
COBS_BRUA2 LHEDGLGDTADGFFGAS-T-PDRRLDIMKDSRIGTFAALTLVIWTGVKASLLMAIIARAG
COBS_BRUME LHEDGLGDTADGFFGAS-T-PDRRLDIMKDSRIGTFAALTLVIWTGVKASLLMAIIARAG
COBS_BRUO2 LHEDGLGDTADGFFGAS-T-PDRRLDIMKDSRIGTFAALTLVIWTSVKASLLMAIIARAG
COBS_BRUA4 LHEDGLGDTADGFFGAS-S-PDRRLDIMKDSRIGTFAALTLIVFVGLKAALLMTIIDRAG
COBS_AZOC5 LHEDGLADTADGFGGGA-S-RLRRLEIMRDSRIGSYGACALVFSLLLRVALLDGLLAL-S
COBS_PSEAE LHLDGLADMADAWVGGLGD-RERTLAIMKDPRSGPVAVVVLVLVLLLKFSALAALLGQGE
COBS_PSEAB LHLDGLADMADAWVGGLGD-RERTLAIMKDPRSGPVAVVVLVLVLLLKFSALAALLGQGE
COBS_PSEA7 LHLDGLADMADAWVGGLGD-RERTLAIMKDPRSGPAAVVALVLVLLLKFGALAALLGAGR
COBS_PSEF5 LHLDGLADSADAWLGGFGD-RERTLSIMKDPRSGPIAVVTLVLVLLLKFTALVALIEQQQ
COBS_PSEPF LHLDGLADSADAWLGGFGD-RERTLTIMKDPRSGPIAVVTLVLVLLLKFAALLALIEQQQ
COBS_PSE14 LHLDGLADSADAWLGGFGD-RERTLQIMKDPRSGPIAVVTLVLVLLLKFAAILALIESHS
COBS_PSEU2 LHLDGLADSADAWLGGFGD-RERTLKIMKDPRSGPIAVVTLVLVLLLKFAAILALIESHA
COBS_PSESM LHLDGLADSADAWLGGFGD-RERTLNIMKDPRSGPIAVVTLVVVLLLKFAAIVALIESHN
COBS_PSEPK LHLDGLADSADAWLGGFGD-RERTLRIMKDPRSGPIAVVTLVLVLLLKFCALWVLVGQGI
COBS_PSEP1 LHLDGLADSADAWLGGFGD-RERTLRIMKDPRSGPIAVVTLVLVLLLKFCALWVLVGQGI
COBS_PSEPG LHLDGLADSADAWLGGFGD-RERTLQIMKDPRSGPIAVVTLVLVLLLKFCALWVLVEQGV
COBS_PSEE4 LHLDGLADSADAWLGGFGD-RERTLQIMKDPRSGPIAVVVLVLVLLLKFCALWVLVERGT
COBS_STUS1 LHLDGLADSADAWLGGFGD-PARTLEIMKDPRSGPVAVVVLVIMLLLKFSALLVVLQAQQ
COBS_PSEMY LHLDGLADTADAWVGGFGD-PGRTLAIMKDPRSGPIAVVVLVLLLLLKFAALLSLLQAGQ
COBS_ALKEH LHLDGLGDSADAWLGGHGD-RLRSLEIMKDPRSGPAAVAVITLALVVKVAALAALLRLDA
COBS_SYNP6 LHLDGAMDTADGLAVPN---PDRRLEVMSDSHTGAFGAIAAIAIISLKTIALCYLPAP--
COBS_SYNE7 LHLDGAMDTADGLAVPN---PDRRLEVMSDSHTGAFGAIAAIAIISLKTIALCYLPAP--
COBS_NOSS1 LHLDGAMDTADGLAVGD---PERRLEVMADSATGAFGAMSAIAILLLKTSALTEIGEY--
COBS_TRIV2 LHLDGAMDTADGLAVGD---PERRLQVMADSATGAFGAMSAIAILLLKTSALTEIGEY--
COBS_THEVB LHLDGAMDTADGLAVRD---QQRRLEVMADSRAGAFGVMAAMVILLLKVTSLSSLE----
COBS_SYNY3 LHLDGVADTADGLAVTN---PSKRLAVMQDSYTGAYGVMAIAVVLLLKTFALASFSDHGL
COBS_PROM3 LHLDGLMDTADGLAAG----RERCLQAMDDSCVGASGVQALLVVVLLQIAALLRLGSL--
COBS_PROMM LHLDGLMDTADGLAAG----RERCLQAMDDSCVGASGVQALLVVVLLQIASLLRLGSL--
COBS_PROMA IHVDGLMDTADGIAAG----PSRCIEAMKDSRIGASGIIALTINLLLQIAALFKLRLL--
COBS_MYCTU LHIDGVADTADGLGCYGPP--QRALAVMRDGSTGPFGVAAVVLVIALQGLAFATLTTVG-
COBS_MYCTA LHIDGVADTADGLGCYGPP--QRALAVMRDGSTGPFGVAAVVLVIALQGLAFATLTTVG-
COBS_MYCBO LHIDGVADTADGLGCYGPP--QRALAVMRDGSTGPFGVAAVVLVIALQGLAFATLTTVG-
COBS_MYCBP LHIDGVADTADGLGCYGPP--QRALAVMRDGSTGPFGVAAVVLVIALQGLAFATLTTVG-
COBS_MYCUA LHIDAVADTADGLGCYGPP--QRALAVMRDGSTGPFGVAAVVLVIAVQGSAFSTLSAAGS
COBS_MYCA1 LHIDGVADTADGLGCYGPP--DRARAVMRDGSTGPFGVAAVVVVVMAQALAFSALAAGRP
COBS_MYCPA LHIDGVADTADGLGCYGPP--DRARAVMRDGSTGPFGVAAVVVVVMAQALAFSALAAGRP
COBS_MYCGI LHIDGLSDTTDALGCYGPA--ERALAVMRDGRAGPFGVAAVAVTVVIQSVAFSQ------
COBS_MYCVP LHIDGLSDTVDALGCYGPP--ERALAVMRDGTAGPFGVAAVAATLLVQSLAFAQ------
COBS_MYCS2 LHIDGFCDTVDGLGCYGPP--ERALAVMRDGSAGPFGVAAVVVVIAVQALTFAE------
COBS_MYCSK MHIDGLSDTVDGLGCYGAP--ERALRVMRDGSAGAFGAASIVVAVGAQTLAFSMLPGGW-
COBS_MYCSS MHIDGLSDTVDGLGCYGAP--ERALRVMRDGSAGAFGAASIVVAVGAQTLAFSMLPGGW-
COBS_MYCSJ MHIDGLSDTVDGLGCYGAP--ERALRVMRDGSAGAFGAASIVVAVGAQTLAFSMLPGGW-
COBS_FRACC LHLDGLADLGDGLGAWRARGRDRALEIMRESTIGAFGAIIVLFVVLLQVGALSTTISAH-
COBS_CORGL MHLDGLADVSDALGSYAAP--PRAREILADPRTGLFGLATAMLSVLLQVAAVASLVDST-
COBS_CORGB MHLDGLADVSDALGSYAAP--PRAREILADPRTGLFGLATAMLSVLVQVAAVASLVDST-
COBS_COREF MHLDGLADVADALGSYAAP--ERAREILADPHTGLMGFSAVLFSLLVQVTAVAALVEGK-
COBS_METAC NHLDGVTDMGDGFMAHGSH--EKKIKALKDTTLGTGGVAFGMLVLLAFYGSIRSIQDEGI
COBS_METMA NHLDGVTDMGDGFMAHGSL--EKKVKALKDTTLGTGGVAFGILVLLAFYGSIRSVQEEGI
COBS_METBF NHLDGITDIGDGFMAHGSL--EKKIKALKDTTIGTGGVSFCILLLLTLYGSIRAVQQEGS
COBS_METBU NHLDGLGDFGDGATAHGSL--EKKVNALKDMSLGIGGVSYTVLALIALYASISSLQAE-V
COBS_PYRAB LHLDGLADWADGIMVKGDR--ERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSMLPFY--
COBS_THEKO LHLDGLADWADGIMAKGDR--ERKIEVMKDVNTGIAGLFAVVIVLLLQVYSLQLLPFY--
COBS_PYRHO LHLDGLADWADGIMVKGDR--EKKIKAMKDINVGVAGIFAVVTVLMLQIYSLQLVPFY--
COBS_PYRFU LHLDGLADWADGIMVKGDR--EKKVRAMKDVNTGIAGTFAVVMILLIQVYSLFSAPFY--
COBS2_ARCFU NHVDGLADFGDALFAPKNR--KR--EAIKDLNTGAGGVAVVVVYFLLLYTLLYRSDFW--
COBS1_ARCFU NHIDGLADFGDAFFAPEER--KK--VAIKDLNLGTGGAVFLCVYFLILFYSFQRVSAF--
COBS_THEAC NHVDAVADAGDAMMIRNR---SRIREVFEDHDVGAGGVFTLIFVYLLALISLSSMDLYIG
COBS_THEVO NHFDATADLGDALMVRDK---SRIPEVIKDHHVGAGGIFAVIFVYGIAVLSLARSTLYIG
COBS_PICTO NHADAVLDLGDTFMVHDP---EKKKIIIKDVYHGTGSVVTFFIIYIITISLLSSFNSIQG
COBS_SULTO HHLDGLLDFGDALMAKDY---NKKIKALHDVEVGAGGIGLLLVYVSIFLTVLLSIKTL--
COBS_SULAC HHLDGLLDMGDALMVGK----ERRPQVLHDLQTGSGAIGLFLVYFSIFLIATLNLNVS--
COBS_SACS2 NHLDGLLDLGDALMIRGNR--EKKIKALKDVEVGSGGIGLLLVYLSIQIVALLKLDFSLY
COBS_PYRCJ NHLDGLADVADALMVRDR---ERARAVLEDPRRGTGGIFAVVATYAVATAS-TASPLQ--
COBS_PYRAE HHLDGLADVGDALLVRDR---EAARRVLEDPRRGTGGIFAVTAVVVTTAAH-LHSPLQ--
COBS_PYRIL HHLDGLADVGDALMVRDR---ERARRVLEDPRRGVGGIFAVVALFVLAASARPESWLD--
COBS_METJA HHIDGLIDFGDGWMAVGDK--RKKLMAMKDRYIGCGGVVFAIFFNLMAVISLSYILDINI
COBS_METTH HHLDGLIDMGDALMSHGSF--ERKIEIMRDPRIGTGGLGLLLIVSSTTIAAIYSLPQGVL
COBS_CARHZ LHIDGLLDSLDAIYSNRDR--EKRLEILKDSRVGSMAVAFFGAFLILKYGSYASFTPKVQ
COBS_DEIRA LHFDGLVDSADALFAMKSP--EQRLDILKDVHVGAFGLATGVLALLLLWSLLGAGLPWY-
COBS_METKA QHFDGLVDVGDALMAGVIS-EEGATKAMRDPRVGVGGLAIGSMALLLAVASFGWIPFE--
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COBS_FUSNN EA-------------AVYAIITYPVVSRFCSVVSCAS------SPYARG-SGMGKTFVDN
COBS_CLOD6 ---------------SLWVIIFMPMIARLGVMLLTYK------TVTPRE-KGMGNLFIGK
COBS_CLOAB ---------------MVKVIILFPVAGRLGSIVSASL------STYARRGEGMGKSFIDY
COBS_ACET2 ---------------LPKALLLFPVAGRIGSLVGAGS------TVYAREGEGLGKSFINC
COBS_CALS4 ---------------LFSALLVSPVIARLSVVFSIAI------SKSARGGKGLGGLLLER
COBS_CLOTE ---------------MSYAIIITPIMSRCTLVFLFLI------GKNAKK-NGTGNLFIEN
COBS_LISMO ---------------ICWLFFVLPIVAKGVTMLLFAK------MTYAGSKEGLGSIFLG-
COBS_LISMF ---------------IGWLFFVLPIVAKGVTMLLFAK------MTYAGSKEGLGSIFLG-
COBS_LISIN ---------------IGWLFFVLPIVAKGVTMLLFAK------MSYAGSKEGLGSIFLG-
COBS_LISW6 ---------------IGWLFFVLPIVAKGVTMLLFAK------MTYAGSNEGLGSIFLG-
COBS_CLONN ---------------IIALILS-PVVAKTVVTLLMCF------SVYARKEGGLGGVFVGK
COBS_ALKOO ------------------LLLLVPVVGRASAVFAASR------TIYARSE-GMGGAFIES
COBS_CLOP1 ---------------DMRILIFIPIASRVINGYFIVS-------QEMLGQSSLAKFFKEG
COBS_CLOPE ---------------DMRVLIFIPIASRAINGYFIVS-------QEMLGQSSLAKFFKEG
COBS_CLOPS ---------------DMRILIFIPIASRTMNGYFIVS-------QEMLGQSSLAKFFKEG
COBS_CLOB8 ---------------SLYTLILIPIISRSVVAYYLLS-------RATIKESTLGTYFKKG
COBS_GEOKA ---------------PPALFAAVPLLSRAGAAWLLSV----GKLAKPTGMAASLREYSSW
COBS_GEOTN ---------------PPALFVAIPLLSRSGAAWLLSV----GKLAKSTGMAASVREYISW
COBS_HALH5 ---------------APREFTWLLLLVPVCLRWMIIVQLIYGKAASDQGMAASLLPYVT-
COBS_ECOLI SI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_ECO57 PI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_SHIFL PI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_SHIF8 PI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_ECOHS PI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_SHISS PI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_ECO24 PI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_ECOL5 PI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_ECOL6 PI--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_SHIDS PI--------------LASLAAACAVSRGIAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_SHIBS PI--------------LALLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_ECOLC PS--------------LASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTC
COBS_SALTY PM--------------LAALAAACAAGRGSAVLLMYRHRYAREEGLGNVFIGKVSGRQTC
COBS_SALCH PM--------------LAALAAACAAGRGSAVLLMYRHRYAREEGLGNVFIGKVSGRQTC
COBS_SALTI PM--------------LAALAAACAAGRGSAVLLMYRHRYAREEGLGNVFIGKVSGRQTC
COBS_SALPA PM--------------LAALAVACAAGHGSAVLLMYRHRYAREEGLGNVFIGKVSGRQTC
COBS_SALAR PV--------------LAALAAACAAGRGSAALLMYRHRYAREEGLGNVFIGKVSGRQTC
COBS_CITK8 PM--------------LAALAMACAAGRGVAVLLMYRHRYAREEGLGNVFIGKVTGRQTC
COBS_KLEP7 HP--------------IAALAAACAVGRGMAALLMYRHRYAREKGLGNLFIGKISLQQTL
COBS_ROSS1 AW--------------LTAVVLAPVLGRWADVYGIVRFPPAREGGLGRTFQSYLR-PGDF
COBS_CHLCH FD----------------VVMAGILLARLVQVLLASALPYARREAGTASAFVAGAGAPHA
COBS_CHLPM FA----------------LIASGVLLGRLSQVLLAASLPYARKEGGTASGFVGGAGRTHA
COBS_CHLTE YG----------------MIAAGAVLSRTAQVLLAARMPYARSDGGTAMAFVEDAGWPHL
COBS_VIBCH -S-------------LVPVWLLAYTLSRAVAASLIRNTPYVS-DTDSSKSKPLAQQLSGT
COBS_VIBC3 -S-------------LVPVWLLAYTLSRAVAASLIRNTPYVS-DTDSSKSKPLAQQLSGT
COBS_VIBVY -D-------------FGLMIVVAYTLSRAVAATLIYDMPYVS-DSDTSKSKPLANAQSST
COBS_VIBVU -D-------------FGLMIVVAYTLSRAVAATLIYDMPYVS-DSDTSKSKPLANAQSST
COBS_VIBPA -D-------------FWLVIVVAYTTSRALAATLIYDMPYVS-DSDTSKSKPLASKQSSS
COBS_PSEA6 -H-------------LLLALAIAYPLSRGLAISHVQHLAYARKNSDNSKSDSLAQPMQPR
COBS_SHESW VV-------------AGSALIVAHTVSRVVAASIIFTEKYVR-DDETSKSKPLSQHQGIN
COBS_SHEPC VV-------------AGSALIVAHTVSRVVAASIIFTEKYVR-DDETSKSKPLSQHQGIN
COBS_SHEB8 VV-------------AGSALIVAHTVSRVVSASIIFSEKYVR-DDETSKSKPLSQHQGIN
COBS_SHEB9 VV-------------AGSALIVAHTVSRVVSASIIFSEKYVR-DDETSKSKPLSQHQGIN
COBS_SHEB5 VV-------------AGSALIVAHTVSRMVSASIIFSEKYVR-DDETSKSKPLSQHQGIN
COBS_SHESM VV-------------AGSAMIVAHTVSRVVAASLIFTEKYVR-DDESSKSKPLAQHQGIN
COBS_SHESR VV-------------AGSAMIVAHTVSRVVAASLIFTEKYVR-DDESSKSKPLAQHQGIN
COBS_SHESA VV-------------AGSAMIVAHTVSRVVAASLIFTEKYVR-DDESSKSKPLAQHQGIN
COBS_SHEON VV-------------AGSAMIVAHTVSRVVAASLIFTETYVR-DDETSKSKPLAQHQGIN
COBS_SHEFN MA-------------AVSALVAGHTLSRVVASSLIFSEQYVR-DDDTSKSKPIAQDQQLN
COBS_SHEDO WA-------------AITGFIVAHTLSRVLAASLIFSVKYVT-DLELEEGKRLSHDQSLN
COBS_SHEPA SS-------------VSLALIVGHCLSRVVAASFIFSEPYVS-DSDTSKSKPLAQEQGIN
COBS_SHEHH SS-------------VSLALIVGHCLSRVVAASFIFSEEYVS-DTDTSKSKPLAQQQGIN
COBS_SHEAM SS-------------VAGGLVLGHTLSRAFAASIIFNHTYVR-EDAESKAKPLAQSMHWD
COBS_AROAE LQ-------------VALALLAAHPLSRLASTSLIHTMQYVR-EDESAKSKPLARRLSAT
COBS_RALN1 AA-------------AMAAMVAAHAASRGMAVSYLLTHDYAR-ME--GKAKPVAQPMGRR
COBS_LEPIC WI-------------FLFTSWFSHSASRWFALLLMMLIPYAR-ENDLSKSKPMIKKLPPF
COBS_LEPIN WI-------------FLFTSWFSHSASRWFALLLMMLIPYAR-ENDLSKSKPMIKKLPPF
COBS_POLSJ SPAELGDDASFSSWYIGAALLTGHVVSRGLPLLLIWLLPHVG-NTASSKSKPLADQISQG
COBS_POLNA VP-EAGEAPAFSSWYVCAALWTGHIVSRGLPLVMIWRLPHVG-DIAISKSKPLADQISAG
COBS_ALBFT TL-------------MVAALFVAHVLSRTWPLLTIRLLPHVG-DAAGSKSKPLADQISVA
COBS_BRADU PWLV------------TLALCAAHCAARAGVPAFMSLVPPARPDGLSASAGAPPGRSVAI
COBS_RHILO PTQA------------LFALVAAHAASRGVLGAFMHLLPPARSDGLSAGAGAVS-LETAI
COBS_SINMW PTGG------------GVALLATAALSRAAMVWHWSRLPPARRDGVAAAAGAPEAPATSV
COBS_RHIME PTGG------------GIALLATAALSRAAMVWHWSRLPPARRGGVAASAGIPEPGATSV
COBV_SINSX PLGA------------AMAILGAACLSRAAMVWHWSSLPPARSSGVAASAGEPEPAATRF
COBS_RHIEC PLAA------------ALAIPAVAALSRGAIAWHWQRLPPAKPDGVAASNGQPNEAAMHF
COBS_RHIJ3 PLTA------------ALAIPAVAALSRGAIAWHWQRLAPAKADGVAASTGQPDEAAMQF
COBS_BRUAB AGYA------------LLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVC
COBS_BRUSU AGYA------------LLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVC
COBS_BRUSI AGYA------------LLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVC
COBS_BRUC2 AGYA------------LLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVC
COBS_BRUA2 AGYA------------LLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVC
COBS_BRUME AGYA------------LLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVC
COBS_BRUO2 AGYA------------LLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVC
COBS_BRUA4 AGYA------------ALALVGCEAASRSGMLAFWHALPSARPGGLSDSVGQPQWETVVC
COBS_AZOC5 PTRA------------ALALIAAASLSRAAGMLLLEFLPPARADGASAAAGQPGADAAVR
COBS_PSEAE A----------------GLLPLAPWLARSSLPLLFLTTPYARPGGLGQAIAEHLPARSLP
COBS_PSEAB A----------------GLLPLAPWLARSSLPLLFLTTPYARPGGLGQAIAEHLPARSLP
COBS_PSEA7 P----------------GLLLLAPWLARSSLPLLFLTTPYARPGGLGQAIAEHLPARSLP
COBS_PSEF5 G----------------FALLLAPLIGRGALLGLFLCTPYVRAGGLGQALADHLPRVAGR
COBS_PSEPF S----------------MALIIVPLIGRAALLGLFLTTSYVRAGGLGQALADHLPRKTGW
COBS_PSE14 S----------------IGLLLAPVIGRAAMLGLFLGTPYVRSGGLGQALADHLPRGPGR
COBS_PSEU2 S----------------VWLLLAPVIGRAAMLGLFLGTPYVRSGGLGQALADHLPRGPGR
COBS_PSESM S----------------IGLLLAPLIGRSAMLALFLGTPYVRSGGLGQALADHLPRSLGR
COBS_PSEPK G----------------AQLLLAPLIGRAAMLGLFLCTPYVRPGGLGQALAEHMPRRAAG
COBS_PSEP1 G----------------AQLLLAPLIGRAAMLGLFLGTPYVRPGGLGQALAEHLPRRAAG
COBS_PSEPG G----------------AQLLLAPLIGRTAMLGLFLCTPYVRPGGLGQALAEHLPRRAAG
COBS_PSEE4 G----------------GWLVLAPVVGRAAMLGLFMGTPYVRKGGLGAALAEHLPRRAAG
COBS_STUS1 P----------------AALVLAPLLGRAALLALFLCTPYVRPNGLGQALAANLPRSRAL
COBS_PSEMY G----------------IYLVLLPWLGRSLLPLLLATTPYVRAGGLGQALVDHLPRRQLP
COBS_ALKEH AL---------------AALLIAPVLGRAAAALLIAGTPYARKQGLAGPLAEAPATRWIG
COBS_SYNP6 ---------------RSLLILLIPVWGRWAQVLAIVRYPYLKA--EGKGAIHKQTGRGAI
COBS_SYNE7 ---------------RSLLILLIPVWGRWAQVLAIVRYPYLKA--EGKGAIHKQTGRGAI
COBS_NOSS1 ---------------RWLVLMAACGWGRWGQQVAIACYPYLKA--TGKGAFHKQAIRSYK
COBS_TRIV2 ---------------RWLVLMAACGWGRWGQQVAIACYPYLKA--TGKGAFHKQAIRSYK
COBS_THEVB ---------------KGSVLVWVLVLGRLAQVWAIARYPYLKP--QGTGQIHKTSGVFPR
COBS_SYNY3 ---------------ASWALIMALGWGRWGQLLAIALYPYLRE--NGKGAMHKRNLKLRP
COBS_PROM3 ---------------APLALLIAAFWGRCAPLWAMARFFYLREGQAGSASFHRRYRQGWQ
COBS_PROMM ---------------APLALLIAAFWGRCAPLWAMARFFYLREGQAGTASFHRRYRKGWQ
COBS_PROMA ---------------ILFAIPIASFWGRYSQIWAISHYPYLNK-EGSSKFLHKKNWRGFL
COBS_MYCTU ----------------IAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVV
COBS_MYCTA ----------------IAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVV
COBS_MYCBO ----------------IAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVV
COBS_MYCBP ----------------IAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVV
COBS_MYCUA RG--------------IAGIAVAVFAGRVTAVLGCRRSVPAAAGSSLGSRVAGTQPISVL
COBS_MYCA1 V---------------PVGVAVAVFAGRVAAVLACRRTVPAAAGSSLGAAVAGSQPATVA
COBS_MYCPA V---------------PVGVAVAVFAGRVAAVLACRRTVPAAAGSSLGATVAGSQPATVA
COBS_MYCGI AG--------------WAAVLVAVAAGRVAVVVACRRGVPAAEGSTLGALVAGTQPLWVA
COBS_MYCVP SG--------------WAAVFIAVVAGRVAVVAACRRGVPAAAGSTLGALVSGTQPRWVA
COBS_MYCS2 LS--------------VLAVVTAVVAGRVAVVAACRRSVPAAAGSTLGAAVAGSQPRWVV
COBS_MYCSK SG--------------AVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVV
COBS_MYCSS SG--------------AVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVV
COBS_MYCSJ SG--------------AVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVV
COBS_FRACC RG--------------TLSILVAAMTSRLAATLACTGAVPPARPDGLGALVAGTVRTRDA
COBS_CORGL -V--------------WWMICFIPVLGRIAGQVTALKNHNAFSPTGFGALVIGTVKFWWI
COBS_CORGB -V--------------WWMICFIPVLGRIAGQVTALKNHHAFSPTGFGALVIGTVKFWWI
COBS_COREF -A--------------GWLVCFIPALSRLGGQIMARVGRTPLSPTGFGAMVVGTVRLWWV
COBS_METAC NVFGSNLPLLM-----FASMFIAEVSAKQSMLTIAAFGKPLPRPENQAYPGLGEMTINGA
COBS_METMA AAFGSNLPFLM-----FASMFIAEVSAKQSMLTIAAFGKPLPRLKEQTYPGLGEMTINGA
COBS_METBF AVFGSNLPVLM-----FESMFIAEVSAKQSMLTIAAFGKPIPPREKQAYPGLGAMTINGA
COBS_METBU LFFSDNAALII-----AISLLIAEIGAKQAMLTVAAFGKPI-------HEGLGSMIINNT
COBS_PYRAB --A----------------IYIAELNSKFSMLLGLATKKPL-------GQGLGAYFMEGM
COBS_THEKO --A----------------LFLAELNSKYAMLLALATKRPL-------GKGLGAYFMEGM
COBS_PYRHO --A----------------IFLAELNSKFAMLLAMATKKPL-------GKGLGAYFMEAL
COBS_PYRFU --S----------------IYLAELNSKMAMLLALATKKPL-------GEGLGKYFMDKL
COBS2_ARCFU --E----------------IALSQVLAKYSMLLLMLLSRPS-------WDGMGSYFMEKI
COBS1_ARCFU --Y----------------IIFSQVLAKFSMLLLLTTSKPA-------WQGMTGFMMEFA
COBS_THEAC IFS----------------IILAEFLSKSMMMITLHRSRPL-------FQGIGSLFIDLY
COBS_THEVO LVG----------------ILIGQVVSGSSMMISLIGSQPF-------VPGLADYFISLF
COBS_PICTO SIA----------------LILSETISRFSMLMSMYKSNSF-------SGGISEIFISYF
COBS_SULTO SFY----------------SLLIAEVESRALGILLLAIMPP-------IEISYMGKIFHK
COBS_SULAC NLW----------------FFLPSEVLARASAISLLGLMKP-------IPGSYLGKVFHD
COBS_SACS2 TIF----------------YLISSNVLSMSLSLYILSTISP-------IPESNLGRIFHD
COBS_PYRCJ -------------------LLLAEVFSKALIVTVAAFSKPF-------KPGLGALFIDGA
COBS_PYRAE -------------------LLLGEVFSKSTALLFAGFSKSF-------KPGLGEAFTEAA
COBS_PYRIL -------------------YIVTDLYSKALALVVAAYSKPF-------KEGLGSLFIVSA
COBS_METJA LY-----------------LLVGEVCAKLGMLSCSTFGNPLIEGTGRYFVKKADEKFLTI
COBS_METTH FQ----------------GLLIGEVSAKVCLTGCARVSRPLDGGTGRHFIMASRSPFTGM
COBS_CARHZ AF----------------TVLISEIILRGTGYLVIYSFPYVGSSLGRGFKDNASTAGLIF
COBS_DEIRA ------------------APLVAAVVARMVVLMPMNAYPAARQESLGAQSRQGRWGLAFL
COBS_METKA ------------------VLVPIEVFSRFTVLPMAAVGEPAPASYSGRVFTEYVDADQVL
COBS_FUSNN IKTCGLIVATVITLLYT----------------IGMLFMPFILFTNYSL----------P
COBS_CLOD6 LTTSMLITAIIYTLLIV----------------ALITKFIFLLPNIVLI----------K
COBS_CLOAB CTLKELAIGIILYAVIF----------------LSVGLSRGY------------------
COBS_ACET2 CGIKEILQGGIIYFIVS----------------LLVLNIKGL------------------
COBS_CALS4 AGLREFVIALLISTIAG----------------YFVMPLKDLA-----------------
COBS_CLOTE VSVKEFIISFIFMIVPS----------------VLLIGYKYSV-----------------
COBS_LISMO VPWWPIVIAQVIVLAVL----------------GLFFSYVGVI-----------------
COBS_LISMF VPWWPVVIAQVIVLVAL----------------GAFFSYIGVI-----------------
COBS_LISIN VPWWPIMIAQGIVLIVL----------------ALFFSYIGLI-----------------
COBS_LISW6 VPWWPIAISQLFVLFIL----------------GLVFSYIGLL-----------------
COBS_CLONN VKPFRVIVAFIISISIG----------------YVLIGYKYVA-----------------
COBS_ALKOO CRTKEGVISIAFSLLLG----------------SMVSIKGAII-----------------
COBS_CLOP1 TGKVDEIILLGIYVLVA----------------LITFFTLGINYL---------------
COBS_CLOPE TGKVDEIILLGIYVLVA----------------LITFFTLGINYL---------------
COBS_CLOPS TGKVDEIILLGIYVLVA----------------LITFFTLGINYL---------------
COBS_CLOB8 TNVYDKLIMIITLIITL----------------IISVILLNIYGI---------------
COBS_GEOKA RDAIWALGLAFVLLSLL----------------CASTAISVQTGA---------------
COBS_GEOTN RDAVWALVLAFLALSLL----------------LVFGGVPVWTSA---------------
COBS_HALH5 THVKNASRVWFLFIAGA----------------CFLLLQNVILTL---------------
COBS_ECOLI V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_ECO57 V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_SHIFL V-------TLGLAAIFA----------------AVLLLGMHGV-----------------
COBS_SHIF8 V-------TLGLAAIFA----------------AVLLLGMHGV-----------------
COBS_ECOHS V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_SHISS V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_ECO24 V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_ECOL5 V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_ECOL6 V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_SHIDS V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_SHIBS V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_ECOLC V-------TLGLAAIFA----------------AVLLPGMHGV-----------------
COBS_SALTY I-------TLGLAVIVA----------------TVLLPGMQGL-----------------
COBS_SALCH I-------TLGLAVIVA----------------TVLLPGMQGL-----------------
COBS_SALTI I-------TLGLAVIVA----------------TVLLLGMQGL-----------------
COBS_SALPA I-------TLGLAVIVA----------------TVLLPGMQGL-----------------
COBS_SALAR V-------TLGLAAIIT----------------TVLLPGMQGL-----------------
COBS_CITK8 V-------TLGLTAILA----------------AILMPGMHGV-----------------
COBS_KLEP7 V-------TMAMAIALA----------------TALL-GLQGL-----------------
COBS_ROSS1 A-------GASVATLAL----------------ALIVGGVGGL-----------------
COBS_CHLCH F--------SALLFTLA----------------LLFPFYTENF-------------PTML
COBS_CHLPM A--------VALALSLM----------------MTLPFFYRDP-------------FLLF
COBS_CHLTE L--------VASISGVV----------------LLFVLLDWQL-------------APSL
COBS_VIBCH D------VAVLSLTALA----------------TLLYFSWQFI----------------G
COBS_VIBC3 D------VAVLSLTALA----------------TLLYFSWQFI----------------G
COBS_VIBVY E------LAILILTGVL----------------AAISLGLGVG----------------L
COBS_VIBVU E------LAILILTGVL----------------AAISLGLGVG----------------L
COBS_VIBPA E------VAILLFTAGV----------------ASLFLGVIQT----------------S
COBS_PSEA6 V------LLWLLASSVP----------------AVLWLPLSSA----------------I
COBS_SHESW E------LFILVASGVL----------------VLLFLKGLAA----------------L
COBS_SHEPC E------LFILVASGVL----------------VLLFLKGLAA----------------L
COBS_SHEB8 E------LLILIASGVL----------------VLLFLKGLAA----------------L
COBS_SHEB9 E------LLILIASGVL----------------VLLFLKGLAA----------------L
COBS_SHEB5 E------LLILIASGVL----------------VLLFLKGLAA----------------L
COBS_SHESM E------LFILIASGVL----------------VLLVLKGIAA----------------L
COBS_SHESR E------LFILIASGVL----------------VLLVLKGIAA----------------L
COBS_SHESA E------LFILIASGVL----------------VLLVLKGIAA----------------L
COBS_SHEON D------LFILIASGVL----------------VLLVLKGIAA----------------L
COBS_SHEFN D------LFILIASGIF----------------VLLWLNGVAA----------------F
COBS_SHEDO D------LFILLASGIF----------------VLFWLNGLAA----------------F
COBS_SHEPA E------LSILLATGIL----------------ALLLVGVMQA----------------L
COBS_SHEHH E------LSILLASGVL----------------ALLLVGLVPA----------------L
COBS_SHEAM EV-----LFLVLSAGVI----------------CLLLTGVGAT----------------L
COBS_AROAE E------LVVAAVFGLA----------------PLALLAPAEA----------------L
COBS_RALN1 D------AAWAALFGGL----------------PLLGFGMACA----------------A
COBS_LEPIC DFALSTFFGCFPAVYFL----------------YQFQNQIPNV----------------L
COBS_LEPIN DFALSTFFGCFPAVYFL----------------YQFQNQIPNV----------------L
COBS_POLSJ S----LLVAFIWSFVVL----------------ALAGLALDAI--------------SLI
COBS_POLNA G----LAIAFSWCFGAL----------------ALASLALDAI--------------NLI
COBS_ALBFT A----LLTGFIWCFMAL----------------ALVISTQSATEYIAINLTDTALLQALL
COBS_BRADU A----------FAVGTL----------------VLTLALGPG---------------KAL
COBS_RHILO A----------GAVLGA----------------IPLLLLGAG---------------GAI
COBS_SINMW A----------LGSGVI----------------LALVLFFLSG----------IPTVAVL
COBS_RHIME A----------LGSGVL----------------LALVLFFLAG----------IPTVAVW
COBV_SINSX A----------LAFGLL----------------VAMLLFYLAQ----------VPALGVI
COBS_RHIEC A----------LVSAGL----------------LAALLIWPP-----------FGLRPLV
COBS_RHIJ3 A----------LASAGL----------------VAALLIWPA-----------FGLRPLV
COBS_BRUAB G----------CGLGLA----------------LLAIGFLPS-----------GGMVALI
COBS_BRUSU G----------CGLGLA----------------LLAIGFLPS-----------GGMVALI
COBS_BRUSI G----------CGLGLA----------------LLAIGFLPS-----------GGMVALI
COBS_BRUC2 G----------CGLGLA----------------LLAIGFLPS-----------GGMVALI
COBS_BRUA2 G----------CGLGLA----------------LLAIGFLPS-----------GGMVALI
COBS_BRUME G----------CGLGLA----------------LLAIGFLPS-----------GGMVALI
COBS_BRUO2 G----------CGLGLA----------------LLAIGFLPS-----------GGMVALI
COBS_BRUA4 G----------FGIGLA----------------FLVFTLIPA-----------GGFLSLI
COBS_AZOC5 S----------ALVGAL----------------LATLLIVPS-----------TGVGATL
COBS_PSEAE W---------VLGVSFG----------------LALAFGL-AG----------------L
COBS_PSEAB W---------VLGGSFG----------------LALAFGL-AG----------------L
COBS_PSEA7 W---------VLGVSFG----------------LALAFGL-SG----------------L
COBS_PSEF5 Q---------VLGLSVL----------------ACLLLGGYSG----------------L
COBS_PSEPF Q---------VLAVSAA----------------VCLVIAGFNA----------------V
COBS_PSE14 K---------VLAATAI----------------ACVLLAGWSG----------------V
COBS_PSEU2 K---------VLLATAI----------------ACVLLAGWSG----------------V
COBS_PSESM K---------VLLVSTV----------------ACVVLAGWSG----------------I
COBS_PSEPK W---------VLLVCVL----------------FCLFLGG--------------------
COBS_PSEP1 W---------VLLVCVL----------------FCLFLGG--------------------
COBS_PSEPG W---------VLLCCAL----------------FCLLLGG--------------------
COBS_PSEE4 W---------VLLGSVL----------------GCVVLGGSPG----------------L
COBS_STUS1 M---------VLALVVI----------------GCLLLGA-TG----------------L
COBS_PSEMY W---------VLGGHVA----------------AMLLLGW-GA----------------L
COBS_ALKEH L---------TALGALL----------------FVTALAGWAG----------------L
COBS_SYNP6 DLLPGA-----IALVLG----------------IGAIARFHSL-------------TVAL
COBS_SYNE7 DLLPGA-----IALVLG----------------IGAIARFHSL-------------TVAL
COBS_NOSS1 DLLPGLC---LMFAISG----------------LFWLVNNHHL-------------LISV
COBS_TRIV2 DLLPGLC---LMVAVSS----------------LFWLVNNHHL-------------LITV
COBS_THEVB DFWPSG---------------------------LLVLLLSFLL-------------PLPL
COBS_SYNY3 DLLLGTM---IIVFGGV----------------GMGYALAIEP-------------WLIL
COBS_PROM3 EALPAFLVLLLALTVVP----------------LLMIVGWPSQ-------------MVLM
COBS_PROMM EALPACLVLLLALTVVP----------------SLMIVGWPSQ-------------MVLM
COBS_PROMA IESIPSYAFLSFLIFIL----------------INIDISIIST-------------PNLI
COBS_MYCTU AAWLAVLLAVSVPAG--------------------PRPWQGPI-----------------
COBS_MYCTA AAWLAVLLAVSVPAG--------------------PRPWQGPI-----------------
COBS_MYCBO AAWLAVLLAVSVPAG--------------------PRPWQGPI-----------------
COBS_MYCBP AAWLAVLLAVSVPAG--------------------PRPWQGPI-----------------
COBS_MYCUA VAWLAVLLFASLAAA--------------------PRPWQGPA-----------------
COBS_MYCA1 AAWVAVLLGMSLVAG--------------------PRPWHGPV-----------------
COBS_MYCPA AAWVAVLLGMSLVAG--------------------PRPWHGPV-----------------
COBS_MYCGI AAWLVAIAGLATLAG--------------------ERAWQGPL-----------------
COBS_MYCVP AGWTVAVAAAAVPVC--------------------ARPWQGPL-----------------
COBS_MYCS2 AGWIVALAALAVFAC--------------------PRPWQGPL-----------------
COBS_MYCSK LVWLAAVAALAIPAT--------------------ERIWQGPL-----------------
COBS_MYCSS LVWLAAVAALAIPAT--------------------ERIWQGPL-----------------
COBS_MYCSJ LVWLAAVAALAIPAT--------------------ERIWQGPL-----------------
COBS_FRACC ALSFLAVCAVAALAGLL-----------DFDGGGPGRALRAVL-----------------
COBS_CORGL ALWLLVTAALAFWCAELISPLSPLTSVNTPFVAGPFPAAINPAWLGGWV----------A
COBS_CORGB ALWLLVTPALAFWCAELISPLSPLTSVNTPFVAGPFPAAINPAWLGGWV----------A
COBS_COREF AAWLVALGVTAGGVAV--------------WAAGPAVVWIVPA-----------------
COBS_METAC TR---KNFLIGFIFGAF----------------VCFLPFGLIG----------------L
COBS_METMA TR---KNFLIGFIFGAV----------------VCCLPFGLIG----------------L
COBS_METBF TR---KNFLIGFVFGAI----------------VCFLPFGWIG----------------L
COBS_METBU TF---PRYAVSFVLGAL----------------VCVLAFGTLG----------------I
COBS_PYRAB NG--RQLAIGVVLYVLL----------------YLPVVIYDPS----------------A
COBS_THEKO NG--RQLALGTLLYVLL----------------GLSVVLFEPR----------------A
COBS_PYRHO DR--NQLLYGTLIYLLL----------------YIPVIIAEPR----------------N
COBS_PYRFU TT--KRVFLGGVLYALL----------------LIPILLYDPQ----------------S
COBS2_ARCFU SS--KDVFIGAVPVVLL----------------CYKVGIESLA----------------A
COBS1_ARCFU RK--RDVVIGSLPLLLV----------------VLKP--LAVF----------------P
COBS_THEAC RKHDSLYTVEFVVIPIV----------------LALLSRASIM----------------I
COBS_THEVO RKHSVGYTIEFLAIPII----------------VSFIFSPLYV----------------V
COBS_PICTO DKPFKITFFNFLVIILI----------------FLIFYKYIIF----------------T
COBS_SULTO NLNNKW---KILSIIVE----------------VVLFGNPYIL----------------I
COBS_SULAC KMRDKLFSIKFLLVQVF----------------AILFSSPVLI----------------L
COBS_SACS2 KLKGKS-----TILLLE----------------LIPFISLYNV----------------I
COBS_PYRCJ RS---------TWPLAL----------------PALAVIICLR----------------P
COBS_PYRAE KR---------QWPAAL----------------PALAVLAYLA----------------P
COBS_PYRIL KR---------QWPAAL----------------PALAVAAWLH----------------P
COBS_METJA G--------IILSLPLL----------------LIFSGIERKI---------------VI
COBS_METTH V---------WIFWAVA----------------AYLLAGVPGA-----------------
COBS_CARHZ TLG----QTLIFTLGAA----------------AFFNFSLIKI----------------L
COBS_DEIRA FA-------------------------------LPALLLPHAW----------------L
COBS_METKA LG--------GILSTVV----------------SLPFSPVATL-----------------
COBS_FUSNN MQFMIRSVLIIVIIVGLLALFAFAFSKLIERKIGGITGDTLGALLEISSLVYIFLFLVIP
COBS_CLOD6 VLGSIIVVFVFIIL----------FKKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLI
COBS_CLOAB IIMIFPILTAVILI------------KYFTRKIGGATGDILGAVCELNQTFYLMTVYAVL
COBS_ACET2 LLAAATMITSFATV------------KFFAGKVGGATGDILGAVCELNQTFFLILFYLFK
COBS_CALS4 LLYVISLSFTCLIS------------KYISKKIGGMTGDTLGAVNEFVELIAFIYFSIL-
COBS_CLOTE IIIVVSFIITLAFL------------NLCNRKIGGITGDCLGANNEIVEMFTMLVFVALL
COBS_LISMO -AYVGVILFTIIYR------------AFVYKRIGGMNGDTLGAGGQMGQLICLFCLVLLW
COBS_LISMF -AYAGVILFTIIYR------------AFVYKRIGGMNGDTLGAGGQMGQLICLFCLVLLW
COBS_LISIN -AYAGVLVFTIIYR------------LFVYKRIGGMNGDTLGAGGQMGQLVCLFCLVLIW
COBS_LISW6 -AYAGVILFTIIYR------------TFVYKRIGGMNGDTLGAGGQMGQLVCLFCLVLVW
COBS_CLONN -LLLITVLFIEIYK------------KLIYSKIDGMTGDTLGAANEIAEIIFMLALLSFK
COBS_ALKOO -PMGITFLGVAMLT------------KKISKILGGMTGDTIGATIEISQTLFMLSAYLLK
COBS_CLOP1 IAILAMGLISFILL------------LKVKKELGGINGDVAGYILVLMEFTGILLLGII-
COBS_CLOPE IAILAMGLISFILL------------LKVKKELGGINGDVAGYILVLMEFTGILLLGII-
COBS_CLOPS IAILAMGLISFILL------------LKVKKELGGINGDVAGYILVLMEFTGILLLGII-
COBS_CLOB8 ILVLLMSLGIKLSV------------EKCRKEFGGISGDVAGFALVIGEVVGILILGIIP
COBS_GEOKA ALAAAAVVLAAAAK------------PWAEKQFGGITGDVLGALIEGGETVLWGVIWLLH
COBS_GEOTN ALAVAMALLALGAK------------PWVEKQFGGVTGDVLGALIEGGETLLWGVVWLLH
COBS_HALH5 CFLLMIWLFPLFWL------------RVCKREIGGMSGDTIGASIEGGELFLWGIMWTFF
COBS_ECOLI AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_ECO57 AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_SHIFL AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_SHIF8 AAMVVTMVAIFILG------------QLLKRTLDGQTGDTLGAAIELGELVFLLALL---
COBS_ECOHS AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_SHISS AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_ECO24 AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_ECOL5 AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIEFGELVFLLALL---
COBS_ECOL6 AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIEFGELVFLLALL---
COBS_SHIDS AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_SHIBS AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_ECOLC AAMVVTMVAIFILG------------QLLKRTLGGQTGDTLGAAIELGELVFLLALL---
COBS_SALTY AAMVVTCAAIFILG------------QLLKRTLGGQTGDTLGAAIELGELIFLLALL---
COBS_SALCH AAMVVTCAAIFILG------------QLLKRTLGGQTGDTLGAAIELGELIFLLALL---
COBS_SALTI ATMVVTLAAIFILG------------QLLKRTLGGQTGDTLGAAIELGELIFLLALL---
COBS_SALPA ATMVVTLAAIFILG------------QLLKRTLGGQTGDTLGAAIELGELIFLLALL---
COBS_SALAR AAIVITLAAIFILG------------QLLKRTLGGQTGDTLGAAIELGELIFLLALL---
COBS_CITK8 AALVVTLAAIFILG------------QLLKRTLGGQTGDTLGAAIELGELIFLLALL---
COBS_KLEP7 RAALITLVLIWGLG------------WALKRTLGGQTGDTLGAAIELGELLFLLALL---
COBS_ROSS1 IALALVWMVTHLLG------------RWWTRDLGGLTGDTYGALCEIAEVVALATLTLSA
COBS_CHLCH WLLGAALVAGSMVG------------MVSYRKIGGVTGDVLGAGSELTEVAVWITGALLL
COBS_CHLPM LLFGAALTAAALIG------------FLSMKKIGGITGDVLGAVSEVTELFVWLAAGVAF
COBS_CHLTE ILLFGSVVALFFVG------------WLSHRKIGGITGDVLGACSELVEAAVWLLAALWL
COBS_VIBCH VMIAASLIFRQIFR------------QWLIRRLGGFTGDCLGAAQQLMEILIYLILLAFL
COBS_VIBC3 VMIAASLIFRQIFR------------QWLIRRLGGFTGDCLGAAQQLMEILIYLILLAFL
COBS_VIBVY LLILFAILFRWAFK------------RWLLARLGGFTGDCLGGAQQLMELGIYLVLIAVV
COBS_VIBVU LLILFAILFRWAFK------------RWLLARLGGFTGDCLGGAQQLMELGIYLVLIAVV
COBS_VIBPA FIVIVLFAFRFAFK------------RWLTKRIGGFTGDCLGAAQQLSELLVYLTLIAFY
COBS_PSEA6 LVIVSACVLRFALK------------HWFKKHIDGYTGDCLGFAQQTQELLIYLLLIITL
COBS_SHESW SLLLVMIGLRRLIV------------VIFRRQIGGYTGDTLGAAQQICEIVCYLVLLIVG
COBS_SHEPC SLLLVMIGLRRLIV------------VIFRRQIGGYTGDTLGAAQQICEIVCYLVLLIVG
COBS_SHEB8 SLLLVMIGLRRLII------------VIFRRQIGGYTGDTLGAAQQIAEIVCYFVLLVVG
COBS_SHEB9 SLLLVMIGLRRLII------------VIFRRQIGGYTGDTLGAAQQIAEIVCYFVLLVVG
COBS_SHEB5 SLLLVMIGLRRLII------------VIFRRQIGGYTGDTLGAAQQIAEIVCYFVLLVVG
COBS_SHESM SLLLVMIGLRRLIV------------VIFRRQIGGYTGDTLGAAQQICEIVCYFVLLVVG
COBS_SHESR SLLLVMIGLRRLIV------------VIFRRQIGGYTGDTLGAAQQICEIVCYFVLLVVG
COBS_SHESA SLLLVMIGLRRLIV------------VIFRRQIGGYTGDTLGAAQQICEIVCYFVLLVVG
COBS_SHEON SLLLVMIGLRRLIV------------VIFRRQIGGYTGDTLGAAQQICEIVCYFVLLVVG
COBS_SHEFN VLFITLWLVRILLG------------GFFRKQIGGYTGDTLGAAQQISEVCCYLVILAVG
COBS_SHEDO VLFISLWALRFCLC------------KYFRSQIGGYTGDTLDAAQQVSEIMCYLIILAVG
COBS_SHEPA VLTLALTIVRYGFV------------RLFTKQIGGYTGDTLGAAQQGSELTCYLLLLVLG
COBS_SHEHH VLITGLVIVRYGFI------------RLFRSQIGGYTGDTLGAAQQGSELSCYLLLLILG
COBS_SHEAM VILVTLFVARSLLA------------RWQSRHIGGYTGDTLGACQQILELVVYLVLLLLW
COBS_AROAE AALTATAAATLWAA------------RVFARRLGGYTGDCLGAAQQGSELACYLGILAAW
COBS_RALN1 IAVAVLLAARWALG------------RYFTRRLGGITGDCLGLAQQVFELLVLWVLLAWT
COBS_LEPIC LGFFLSSIFVFYFR------------NYFNKWIEGFTGDCLGFIQQGTELLFYLGITVSW
COBS_LEPIN LGFFLSSIFVFYFR------------NYFNKWIEGFTGDCLGFIQQGTELLFYLGITVSW
COBS_POLSJ VACSFSLLALLWMG------------ALFKRRLQGFTGDCLGATQQVCEIAFYLGLAVSL
COBS_POLNA VACGFSVLALLGLL------------RFFRRRLQGFTGDCLGTTQQVCEIAFYLGLAVSL
COBS_ALBFT SAVVASCVAWAVMA------------RWFWRRLQGFTGDCLGATQQVCELAFYLGLAVGL
COBS_BRADU VGLILLSLAGLILA------------RLAIRQIGGQTGDILGAFEQTGEIVILLVAAAFQ
COBS_RHILO AALILLGLLFAAFH------------ALCLNQIGGQTGDTIGALQQVSEIAVLLVASVAL
COBS_SINMW LSFGAFVLAVLSFT------------RIASRKLGGHTGDTIGATQQLTEVAVLGALALAI
COBS_RHIME LSFAAFGLAVPGFT------------RIASRKLGGHTGDTIGATQQLTEVAVLGALALAI
COBV_SINSX AALVAFLATVKGFA------------RLAMRKIGGQTGDTIGATQQLTEIAVLGALALTV
COBS_RHIEC AGLLVAGVAGFAFT------------VFIRRKLAGHTGDTLGATQQICEIATLCALATAL
COBS_RHIJ3 ASLLATGIAGFAFT------------AFIRRKLAGHTGDTLGATQQICEIATLCALATAL
COBS_BRUAB NALVLMTVVLFGFA------------RLCMAKIGGQTGDTLGAAQQIGSLAALIGLVMAL
COBS_BRUSU NALVLMTVVLFGFA------------RLCMAKIGGQTGDTLGAAQQIGSLAALIGLVMAL
COBS_BRUSI NALVLMTVVLFGFA------------RLCMAKIGGQTGDTLGAAQQIGSLAALIGLVMAL
COBS_BRUC2 NALVLMTVVLFGFA------------RLCMAKIGGQTGDTLGAAQQIGSLAALIGLVMAL
COBS_BRUA2 NALVLMTVVLFGFA------------RLCMAKIGGQTGDTLGAAQQIGSLAALIGLVMAL
COBS_BRUME NALVLMTVVLFGFA------------RLCMAKIGGRTGDTLGAAQQIGSLAALIGLVMAL
COBS_BRUO2 NALVLMTVVLFGFA------------RLCMAKIGGQTGDTLGAAQQIGSLAALIGLVMAL
COBS_BRUA4 NALVLATGLLFGFA------------RLCIAKIGGQTGDTLGAAQQIGSVAVLAGLVMAL
COBS_AZOC5 MAIGLSVLALFAMT------------RLSNRLIGGQTGDVAGAVQQLCEIAFLMGVLIYA
COBS_PSEAE LALLVTLMLFAWLR------------SRFLARLGGTTGDTAGALVELTECAVLVALAL--
COBS_PSEAB LALLVTLMLFAWLR------------SRFLARLGGTTGDTAGALVELTECAVLVALAL--
COBS_PSEA7 LALLVTLMLFAWLR------------SRFLARLGGTTGDTAGALVELTECAVLVALAL--
COBS_PSEF5 WAVLLATVLFFWLR------------QVMMRRLGGTTGDTAGAVLELLETAVLLGVALF-
COBS_PSEPF VALLLAVIVFIWLR------------HLMVRRLGGTTGDTAGALLELLEMSVLVGLALF-
COBS_PSE14 AVLLVCAVCFFWLR------------QLMMRRLGGCTGDTAGALLELLELAVLLTLALL-
COBS_PSEU2 AVLLVCAVCFFWLR------------QLMMRRLGGCTGDTAGALLELLELAVLLTLALL-
COBS_PSESM AALLVCAVCFYWLR------------HMMMRRLGGSTGDTAGALLELLELAVVLTLALL-
COBS_PSEPK WSVLLALAVFAWLR------------HLMCRRLGGTTGDTAGALLELLELAVVLGLALGL
COBS_PSEP1 WSVLLALAVFAWLR------------HLMCRRLGGTTGDTAGALLELLELAVVLGLALGL
COBS_PSEPG WVVLLAVAVFAWLR------------HLMYRRLGGATGDTAGALLELLELAVVLGLALGL
COBS_PSEE4 WMLLLSLGVFLWLR------------RLMCKRLGGTTGDTAGAMVELLELAVLVGLALMV
COBS_STUS1 LALTLAGVTFLLAR------------RAMLRRLGGTTGDTAGALLELVECAVLVGLALQV
COBS_PSEMY IALATALALFVWLR------------RALMQRLGGTTGDTAGALLELAECAALLALALSL
COBS_ALKEH AAVLGVVAVGVWAQ------------HLMMRRLDGFTGDTAGALVEVAELAALLGLLAVL
COBS_SYNP6 QLLAIGLLWAWATG------------AWLQKKLGGQTGDTYGAIVEWTEALIWVSFTIGQ
COBS_SYNE7 QLLAIGLLWAWATG------------AWLQKKLGGQTGDTYGAIVEWTEALIWVSFTIGQ
COBS_NOSS1 VVLIAGSAIATLTA------------AWFNHKLGGHTGDTYGAVVEWTEALFLCVLTILT
COBS_TRIV2 VGLITGSAIASLTA------------AWFNHKLGGHTGDTYGAVVEWTEALFLCVLTILT
COBS_THEVB GQLLFGLLLILLIP------------AWFQSQLGGHTGDSYGAVVEWTEALLLVAFTVGS
COBS_SYNY3 GATGSSALIAWAVG------------RWFAQQFKGHTGDTYGAVVEWSEVLILLGLSLV-
COBS_PROM3 AGIGVGVLPAFLVP------------ELLGRRLGGHSGDSYGASVVLVETITLLLLAVLL
COBS_PROMM AGIGVGVLPAFLVP------------ELLGRRLGGHSGDSYGASVVLVETITLLLLAVLL
COBS_PROMA IGIIVGFLPALIIP------------HLLARRLGGHSGDSYGASVVLVETCMLIIFSIIL
COBS_MYCTU -AVLVAVTAGAALA------------AHCVHRFGGVTGDVLGSAIELSTTVSAVTLAGLA
COBS_MYCTA -AVLVAVTAGAALA------------AHCVHRFGGVTGDVLGSAIELSTTVSAVTLAGLA
COBS_MYCBO -AVLVAVTAGAALA------------AHCVHRFGGVTGDVLGSAIELSTTVSAVTLAGLA
COBS_MYCBP -AVLVAVTAGAALA------------AHCVHRFGGVTGDVLGSAIELSTTVSAVTLAGLA
COBS_MYCUA -AVVAAVCAGTLLI------------RHCVRRFGGITGDVLGCAIELATTVTAVVLAALV
COBS_MYCA1 -AVLLGLGCGAVLV------------RHCVRRFGGISGDVLGAAIELTATVSAVALAALV
COBS_MYCPA -AVLLGLGCGGVLV------------RHCVRRFGGISGDVLGAAIELTATVSAVALAALV
COBS_MYCGI -AVVVAVACSVVMV------------AHCVRRFGGITGDVLGAAVEVTTTVTALGLAIA-
COBS_MYCVP -VVALALACSAGLV------------AHCVRRFGGITGDVLGAALEVTTTIAAVGLAVR-
COBS_MYCS2 -AVLVAIGCSLALV------------AHCVRRFGGITGDVLGAAVEVTTTLAALGLAIG-
COBS_MYCSK -TVVVAVGMTALLV------------RHCVRRFGGITGDVLGAAIEVTTTVVAVGLVIR-
COBS_MYCSS -TVVVAVGMTALLV------------RHCVRRFGGITGDVLGAAIEVTTTVVAVGLVIR-
COBS_MYCSJ -TVVVAVGMTALLV------------RHCVRRFGGITGDVLGAAIEVTTTVVAVGLVIR-
COBS_FRACC -AVWVGTGVSFLLR------------RYLLTRFGGITGDILGGLIEITAAATLLVMAMTI
COBS_CORGL ITAVVACVFAALFS------------RRLSRSFGGLNGDCIGACIHLGASISAVMFAVVA
COBS_CORGB ITAVVACVFAALFS------------RRLSRSFGGLNGDCIGACIHLGASISAVMLAVVA
COBS_COREF -AGIIACVVSESAG------------RHVSRRFGGVNGDCIGAGIHLSAAVVAVFCAVAV
COBS_METAC IPYLAACISALVLL------------NRSYAHFGGLNGDGIGTANEIGRITALIIIAVTL
COBS_METMA IPYLAACISALVLL------------NRSYAHFGGLNGDGIGTANEIGRITALIVIAVTL
COBS_METBF LPYLGACLVALVIL------------NRSYAHFGGLNGDGIGTANEIGRVTALIILAVLL
COBS_METBU IGYISAIVTAFVIL------------NISIRHFKGINGDCIGTSNEIARIIVLMVLTVAI
COBS_PYRAB LFGVMGLVFAWYVI------------RLSLENFGGINGDCLGAMAEITRAGTLVILSFSL
COBS_THEKO LAGILGLLFGVHII------------RISLKNFDGLNGDCLGATAEITRAGTLVVMALVW
COBS_PYRHO LVSFLGLFIGLYAV------------KISLDNFGGLNGDCIGAVAEITRVGTLVVITLGW
COBS_PYRFU IFALLGLVGGIYAV------------KISLDNFGGLNGDCIGAVGEITRGATLLILGVWA
COBS2_ARCFU L--ASGFAVVLLLK------------AYSEKHFGGVNGDVIGSANCLTFAASLSALTIAG
COBS1_ARCFU L--LFAITISLLVK------------RYAEEKFGGVSGDVVGASNCLVFAGSLLVCYFLA
COBS_THEAC SVAL-AFLIFIIVK------------MAVIRRFGGINGDLAGFIGELGRSIFLMISLIMA
COBS_THEVO IVAL-NLLIVQLTK------------TMISRRFGGINGDVIGFLGEFSRSLFIFMLIIIA
COBS_PICTO MFSLISIVISYYFK------------SHEQKIFNGINGDIIGFTGELSRLISLLLILISF
COBS_SULTO SFAI----LLLFFY------------FLGYSTLKGSSGDFIGAIITLSFPIFLLIAERSC
COBS_SULAC AYVI----LLLVFY------------LMAKLVFDGMSGDIVGAIITLSFPIYLLVAEKTC
COBS_SACS2 VFII----FYMIMY------------KICGSLG-GSSGDIAGASITLSFPLFLITDEITN
COBS_PYRCJ AATLAALAVALALY------------AVAYQHLGGANGDVFGYLLEVSRVAYIVTWHM--
COBS_PYRAE VTTAVSLATSALLY------------QLAYRHLGGANGDVYGYLLEVSRSAFVIWSAYVP
COBS_PYRIL AAFLAATVLSLFFY------------VAAYKHLGGANGDLLGALLEVTRALYLATVDLST
COBS_METJA IAIITTIITGLCMA------------KIAKRHFGGVNGDVLGASNEITRVVVLLSIIASI
COBS_METTH VSVAVAVLSGVFIG------------LVARRNFYWSTGDVLGASNEVGRMMSLLGLLAAI
COBS_CARHZ IILLLAYLFAFVVA------------ARWQQFFGGLTGDNYGGIMELTGLFVPVAVLLIN
COBS_DEIRA AALVALLGVTLVAA------------WAARRLGGGLSGDVYGLLIVVAELLVLGFYGWGF
COBS_METKA TCAVCSAVVAWTCL------------EAARRTIRGVNGDFLGASIWVSRVLSAVCLSSLP
.** .
COBS_FUSNN TFFIG---------------
COBS_CLOD6 FMFF----------------
COBS_CLOAB YFRG----------------
COBS_ACET2 --------------------
COBS_CALS4 --------------------
COBS_CLOTE YIN-----------------
COBS_LISMO GLV-----------------
COBS_LISMF GLI-----------------
COBS_LISIN GLM-----------------
COBS_LISW6 GLI-----------------
COBS_CLONN GCGLL---------------
COBS_ALKOO SIII----------------
COBS_CLOP1 --------------------
COBS_CLOPE --------------------
COBS_CLOPS --------------------
COBS_CLOB8 --------------------
COBS_GEOKA SSVMG---------------
COBS_GEOTN SSAMG---------------
COBS_HALH5 LSVTA---------------
COBS_ECOLI --------------------
COBS_ECO57 --------------------
COBS_SHIFL --------------------
COBS_SHIF8 --------------------
COBS_ECOHS --------------------
COBS_SHISS --------------------
COBS_ECO24 --------------------
COBS_ECOL5 --------------------
COBS_ECOL6 --------------------
COBS_SHIDS --------------------
COBS_SHIBS --------------------
COBS_ECOLC --------------------
COBS_SALTY --------------------
COBS_SALCH --------------------
COBS_SALTI --------------------
COBS_SALPA --------------------
COBS_SALAR --------------------
COBS_CITK8 --------------------
COBS_KLEP7 --------------------
COBS_ROSS1 PMRLLAT-------------
COBS_CHLCH SDYLLF--------------
COBS_CHLPM TAF-----------------
COBS_CHLTE KGLFWAIA------------
COBS_VIBCH QHEVMI--------------
COBS_VIBC3 QHEVMI--------------
COBS_VIBVY Q-------------------
COBS_VIBVU Q-------------------
COBS_VIBPA QNI-----------------
COBS_PSEA6 PKTVNEQTIGFLL-------
COBS_SHESW SIL-----------------
COBS_SHEPC SIL-----------------
COBS_SHEB8 NIL-----------------
COBS_SHEB9 NIL-----------------
COBS_SHEB5 NIL-----------------
COBS_SHESM SIL-----------------
COBS_SHESR SIL-----------------
COBS_SHESA SIL-----------------
COBS_SHEON GIL-----------------
COBS_SHEFN LS------------------
COBS_SHEDO LSA-----------------
COBS_SHEPA VSW-----------------
COBS_SHEHH VSW-----------------
COBS_SHEAM SQS-----------------
COBS_AROAE NFI-----------------
COBS_RALN1 SS------------------
COBS_LEPIC NSI-----------------
COBS_LEPIN NSI-----------------
COBS_POLSJ --------------------
COBS_POLNA --------------------
COBS_ALBFT --------------------
COBS_BRADU MGR-----------------
COBS_RHILO SS------------------
COBS_SINMW --------------------
COBS_RHIME --------------------
COBV_SINSX --------------------
COBS_RHIEC --------------------
COBS_RHIJ3 --------------------
COBS_BRUAB --------------------
COBS_BRUSU --------------------
COBS_BRUSI --------------------
COBS_BRUC2 --------------------
COBS_BRUA2 --------------------
COBS_BRUME --------------------
COBS_BRUO2 --------------------
COBS_BRUA4 --------------------
COBS_AZOC5 RPH-----------------
COBS_PSEAE --------------------
COBS_PSEAB --------------------
COBS_PSEA7 --------------------
COBS_PSEF5 --------------------
COBS_PSEPF --------------------
COBS_PSE14 --------------------
COBS_PSEU2 --------------------
COBS_PSESM --------------------
COBS_PSEPK --------------------
COBS_PSEP1 --------------------
COBS_PSEPG --------------------
COBS_PSEE4 --------------------
COBS_STUS1 GR------------------
COBS_PSEMY --------------------
COBS_ALKEH ANSAG---------------
COBS_SYNP6 V-------------------
COBS_SYNE7 V-------------------
COBS_NOSS1 --------------------
COBS_TRIV2 --------------------
COBS_THEVB AS------------------
COBS_SYNY3 --------------------
COBS_PROM3 TAG-----------------
COBS_PROMM PAG-----------------
COBS_PROMA PAS-----------------
COBS_MYCTU RL------------------
COBS_MYCTA RL------------------
COBS_MYCBO RL------------------
COBS_MYCBP RL------------------
COBS_MYCUA RL------------------
COBS_MYCA1 RV------------------
COBS_MYCPA RV------------------
COBS_MYCGI --------------------
COBS_MYCVP --------------------
COBS_MYCS2 --------------------
COBS_MYCSK --------------------
COBS_MYCSS --------------------
COBS_MYCSJ --------------------
COBS_FRACC PTPVLHTLGLH---------
COBS_CORGL NAMV----------------
COBS_CORGB NAMV----------------
COBS_COREF AGMTG---------------
COBS_METAC ELSLN--TGGLEWTLL----
COBS_METMA KLSLNGYLGGLEWTLL----
COBS_METBF QLSLNGYMGGFKWTLL----
COBS_METBU TAVNNG-YGGLFWTPL----
COBS_PYRAB CFTT----------------
COBS_THEKO WYL-----------------
COBS_PYRHO RI------------------
COBS_PYRFU --------------------
COBS2_ARCFU QL------------------
COBS1_ARCFU D-------------------
COBS_THEAC QSSVLSTYDILSKIMSSL--
COBS_THEVO HYNVASTYDIFSKMLSSFTS
COBS_PICTO KLI-----------------
COBS_SULTO YLF-----FTSLFSLI----
COBS_SULAC YHY-----FIFQYSLTLP--
COBS_SACS2 LNYSLLSILCYLFSHLH---
COBS_PYRCJ --------------------
COBS_PYRAE VPTAF---------------
COBS_PYRIL SLINGLF-------------
COBS_METJA KVFSIYLLG-----------
COBS_METTH RLTGL---------------
COBS_CARHZ NIGVV---------------
COBS_DEIRA TPL-----------------
COBS_METKA W-------------------