CLUSTAL format seed alignment for MF_00952
_____________________________________________________________________________
Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
Q6F0G3_MESFL ---------------------------------------------------MAKYLVLLE
F0V2L5_MYCS3 ----------------------------------------------------MRELMFVE
Q9PPP9_UREPA ---------------------------------------------------MQKDLIVVE
TOP1_MYCGA ------------------------------------------------MTNHSSKILVIE
TOP1_MYCPN ---------------------------------------------------MSKNLVVIE
TOP1_MYCGE ---------------------------------------------------MIKNLVVIE
Q3M6J7_TRIV2 ---------------------------------------------------MPKRLLVVE
Q4AA55_MESHJ ----------------------------------------------------MEKLIIVE
B3PMD8_META1 ---------------------------------------------------MDQKVLIVE
TOP1P_MIMIV ----------------------------------------------------MSILILLE
Q8F5G0_LEPIN ----------------------------------------------------MSLLIIVE
TOP1_BORBU --------------------------------------------------MQNKKLIIVE
H8H3H1_DEIGI -----------------------------------------------------MPLLIVE
B1VAJ5_PHYAS ---------------------------------------------------MKKKVIIVE
TOP1_FERIS ----------------MAKSKVVEKDKKNELDNQSADIELKGQSKNEESKGGKKKVIIVE
TOP1_THEMA ------------------------------------------------MSKKVKKYIVVE
B2V7T0_SULSY --------------------------------------------------MSEKKIVIVE
TOP1_AQUAE -----------------------------------------------------MELFIVE
D3SM80_THEAH ----------------------------------------------------MMRLFLVE
G8QVT8_SPHPG -------------------------------------------------MDDTKVLIIVE
TOP1_SYNE7 ----------------------------------------------------MPKLVIVE
TOP1_SYNY3 ----------------------------------------------------MSKLVIVE
TOP1_STRCO ------------------------------------------MSPTSETAKGGRRLVIVE
TOP1_MYCTU ------------------------------------MADPKTKGRGSGGNGSGRRLVIVE
TOP1_MYCLE --------------------------------------MKGPRGSRSGRNGSPRRLVIVE
I0II60_PHYMF -----------------------------------------------MKDAQGRHLVIVE
J9Z7K0_LEPFM ------------------------------------------------------------
TOP1_BUCAI ---------------------------------------------------MQKSLVIVE
TOP1_BUCAP ---------------------------------------------------MCKSLVIVE
TOP1_PSEAE ---------------------------------------------------MGKSLVIVE
TOP1_VIBCH ---------------------------------------------------MGKSLVIVE
TOP1_ECOLI ---------------------------------------------------MGKALVIVE
TOP1_SALTY ---------------------------------------------------MGKALVIVE
TOP1_HAEIN ---------------------------------------------------MSKSLVIVE
TOP1_PASMU ---------------------------------------------------MSKSLVIVE
TOP1_CAMJE ---------------------------------------------------MKKNLIIVE
TOP1_HELPY ----------------------------------------------------MKHLIIVE
TOP1_HELPJ ----------------------------------------------------MKHLIIVE
TOP1_TREPA -------------------------------------MEVRGLQPKRQKTFARKHLVIVE
TOP1_LACLA ----------------------------MPTSTKSKTKTTTKKKTTRKRVTPGKNLVIVE
TOP1_STAS1 ---------------------------------------------------MAENLVIVE
TOP1_STAAB ---------------------------------------------------MADNLVIVE
TOP1_STAA8 ---------------------------------------------------MADNLVIVE
TOP1_STAAU ---------------------------------------------------MADNLVIVE
TOP1_STAAM ---------------------------------------------------MADNLVIVE
TOP1_STAHJ ---------------------------------------------------MADNLVIVE
TOP1_STAES ---------------------------------------------------MADNLVIVE
TOP1_BACSU ---------------------------------------------------MSDYLVIVE
TOP1_HALH5 ---------------------------------------------------MADYLVIVE
A5CVH7_VESOH ---------------------------------------------------MAKNLVIVE
Q28MI5_JANSC -----------------------------------------------------MPVVVVE
TOP1_XYLFT ---------------------------------------------------MPKHLLIVE
TOP1_XYLFA ---------------------------------------------------MPKHLLIVE
TOP1_RICTY -----------------------------------------------------MKLVIVE
TOP1_RICPR -----------------------------------------------------MKLVIVE
TOP1_RICBR -----------------------------------------------------MKLVIVE
TOP1_RICFE -----------------------------------------------------MKLVIVE
TOP1_RICCN -----------------------------------------------------MKLVIVE
B7J7I8_ACIF2 ----------------------------------------------------MTKLLIVE
Q7WXW8_PSEAI -----------------------------------------------------MHIVIIE
C6XEP4_METGS ---------------------------------------------------MSKTLIIVE
B1M9R9_METRJ -----------------------------------------------------MKLMVVE
TOP1P_XYLFA -----------------------------------------------------MKLMIIE
C8W7T0_LANP1 -----------------------------------------------------MILVVTE
E1RJ15_METP4 -----------------------------------------------------MHLIIAE
C7P1M5_HALMD -----------------------------------------------------MELIITE
TOP1_THEAC --------------------------------------------------MDGFRIIIAE
TOP1_ARCFU --------------------------------------------------MVMSWLIITE
B5IE55_ACIB4 ----------------------------------------------------MNILVIAE
B1L3G6_KORCO ----------------------------------------------------MTTLILTE
TOP1_AERPE --------------------------------------------------------MVAE
A3DP02_STAMF MGDKAKKSIIDYILSYSEKQKKKPVKTKEKTSSKKAIEKTEIQITHNIWDLIGKIVVIAE
B8D5I1_DESA1 ----------------------------------------MVSKSIRIWDLKGRILVIAE
K0IBM4_NITGG ----------------------------------------------------MYTLVVCE
TOP1_METTH ---------------------------------------------MRSLSGKMHEVIICE
F6D5C7_METPW ----------------------------------------------------MHEVIICE
TOP1_METJA ------------------------------------------------MAEIMTALIICE
TOP1_PYRAB -----------------------------------------------------MILVIAE
TOP1_PYRHO -----------------------------------------------------MILIIAE
Q6F0G3_MESFL SPSKVEKIKHYLEK-----------------NFQEDSFEVLASGG---HIN--RIADSGP
F0V2L5_MYCS3 SPAKIKSISKYLSG---------------------RNLKVFATYG---HIR--ELSK---
Q9PPP9_UREPA SPNKIKSIQSYLGD----------------------SYNVIATCG---HLR--ELA----
TOP1_MYCGA SPNKVKTIKKYLTD----------------------DYEIVATVG---HIR--DLPK---
TOP1_MYCPN SPNKVKTLQKYLPN----------------------DFEIVSTIG---HIR--EMVH---
TOP1_MYCGE SPNKVKTLKQYLPS---------------------DEFEIVSTVG---HIR--EMVY---
Q3M6J7_TRIV2 SPGKVKKLSQILGS----------------------EWIVRASCG---HIR--ELSDEGE
Q4AA55_MESHJ SPNKINTISSYLDS----------------------SYKVTACVG---HIT--NLAKTGQ
B3PMD8_META1 SPNKVKTIQQYVGS----------------------DYNVVSSVG---HIL--KLSTSGV
TOP1P_MIMIV SPGKISKISSILGK----------------------NYVVKASMG---HFR--DLDP---
Q8F5G0_LEPIN SPSKAKTIAGYLGK----------------------EFRILATLG---HVA--DLPK---
TOP1_BORBU SPTKAKTIKKFLDE----------------------SFLVEACIG---HVV--DLPNNAK
H8H3H1_DEIGI SPKKAKQIASYLGR----------------------DWTVKACFG---HVR--DLPATKA
B1VAJ5_PHYAS SPAKIKTLSRFFDD----------------------KVEILSSKG---HIR--DLSLSGK
TOP1_FERIS SPAKAKTIERILGN----------------------DYQVISSKG---HIR--DLPQ---
TOP1_THEMA SPAKAKTIKSILGN----------------------EYEVFASMG---HII--DLPK---
B2V7T0_SULSY SPKKAKEISHFLGK----------------------DFIVKATVG---HFK--DLPE---
TOP1_AQUAE SPTKAKTIQKFLGK----------------------GFLVKATLG---HVK--DLPE---
D3SM80_THEAH SPTKAKTIQKYLGK----------------------DWKVLASMG---HIK--DLPE---
G8QVT8_SPHPG SPTKAKTITKFLPK----------------------TCKVVASKG---HIR--DLPE---
TOP1_SYNE7 SPTKARTIRNYLPK----------------------DYRVEASMG---HVR--DLPQSAS
TOP1_SYNY3 SPTKARTIRNYLPQ----------------------DYRVEASMG---HVR--DLPASAE
TOP1_STRCO SPAKAKTIKGYLGP----------------------GYVVEASVG---HIR--DLPSGAA
TOP1_MYCTU SPTKARKLASYLGS----------------------GYIVESSRG---HIR--DLPRAAS
TOP1_MYCLE SPTKARKLSGYLGS----------------------AYIVESSRG---HIR--DLPRTAA
I0II60_PHYMF SPTKAKTINKYLGR----------------------DYHVMASVG---HVR--DLPKSAP
J9Z7K0_LEPFM -------------------------------------------MG---HVK--DLPP---
TOP1_BUCAI SPAKAKTINQYLGS----------------------EYIVKSSIG---HIR--DLTKGKL
TOP1_BUCAP SPVKAKTISKYLGK----------------------QYIVKSSVG---HVR--DLINNKS
TOP1_PSEAE SPAKAKTINKYLGS----------------------QYVVKSSIG---HIR--DLPTSGS
TOP1_VIBCH SPAKAKTINKYLGK----------------------DFIVKSSVG---HVR--DLPTAGQ
TOP1_ECOLI SPAKAKTINKYLGS----------------------DYVVKSSVG---HIR--DLPTSGS
TOP1_SALTY SPAKAKTINKYLGN----------------------DYVVKSSVG---HIR--DLPTSGS
TOP1_HAEIN SPAKAKTINKYLGS----------------------QYVVKSSVG---HIR--DLPTVGS
TOP1_PASMU SPAKAKTINKYLGS----------------------NYVVKSSVG---HIR--DLPTVGS
TOP1_CAMJE SPAKAKTIGNFLGK----------------------DYEVIASKG---HIR--DLPK---
TOP1_HELPY SPAKAKTIKNFLDK----------------------NYEVIASKG---HVR--DLSK---
TOP1_HELPJ SPAKAKTIKNFLDK----------------------NYEVVASKG---HVR--DLSK---
TOP1_TREPA SPAKAQTIEKYLGT----------------------QYVVRASMG---HVI--DLPK---
TOP1_LACLA SPAKAKTIEKYLGR----------------------NYKVVASVG---HIR--DLKK---
TOP1_STAS1 SPAKAKTIEKYLGK----------------------KYKVIASMG---HVR--DLPR---
TOP1_STAAB SPAKAKTIEKYLGK----------------------KYKVIASMG---HVR--DLPR---
TOP1_STAA8 SPAKAKTIEKYLGK----------------------KYKVIASMG---HVR--DLPR---
TOP1_STAAU SPAKAKTIEKYLGK----------------------KYKVIASMG---HVR--DLPR---
TOP1_STAAM SPAKAKTIEKYLGK----------------------KYKVIASMG---HVR--DLPR---
TOP1_STAHJ SPAKAKTIEKYLGK----------------------KYKVIASMG---HVR--DLPR---
TOP1_STAES SPAKAKTIEKYLGK----------------------RYKVIASMG---HVR--DLPR---
TOP1_BACSU SPAKAKTIERYLGK----------------------KYKVKASMG---HVR--DLPK---
TOP1_HALH5 SPAKAKTIGKYLGK----------------------KYTVKASMG---HVR--DLPK---
A5CVH7_VESOH SPTKAKTIEKFLGK----------------------DFSVKSSIG---HIR--DMPK---
Q28MI5_JANSC SPAKAKTINKYLGS----------------------DYTVLASYG---HVR--DLPS---
TOP1_XYLFT SPAKAKTINKYLGK----------------------DFTVLASYG---HVR--DLVP---
TOP1_XYLFA SPAKAKTINKYLGK----------------------DFTVLASYG---HVR--DLVP---
TOP1_RICTY SPAKAKTINKYLGD----------------------EFKVIASFG---HIR--DLPS---
TOP1_RICPR SPAKAKTINKYLGD----------------------EFKVIASFG---HIR--DLPS---
TOP1_RICBR SPAKAKTINKYLGD----------------------EFKVIASFG---HIR--DLPS---
TOP1_RICFE SPAKAKTINKYLGD----------------------EFKVIASFG---HIR--DLPS---
TOP1_RICCN SPAKAKTINKYLGD----------------------EFKVIASFG---HIR--DLPS---
B7J7I8_ACIF2 SPTKAHHIQAMLGS----------------------GWSVKATVG---HIR--DLPIKGD
Q7WXW8_PSEAI APGKLKKLRSLLPS-----------------IRPDVTWQVEATAG---HIR--DLPVHGQ
C6XEP4_METGS SPTKAKKLSEYLGS----------------------EYLVKASFG---HVR--DLPTSN-
B1M9R9_METRJ SPNKVASIQGYLGD----------------------DWKVVASSG---HIR--DLPQ---
TOP1P_XYLFA SPGKIEKLSTILGD----------------------GWKIAASVG---HVR--DLPQ---
C8W7T0_LANP1 KNDAAQQIARLLSESGKPEADKVYNTPVYRFRRGGEDYVAIGLRG---HILQPDFPLALK
E1RJ15_METP4 KNIAAQRIAGILAENKKPSVKREEGVNTY-------SFDDKVAIGLRGHVV--EID----
C7P1M5_HALMD KENAARRIAEILSDGAATAERENGVNVY--------RWGTKRCMGLSGHVV--GVD----
TOP1_THEAC KADAGRRIAYFLSG-GQVKSHRAKGTSYLEFEYNGSKTYLIPLSG---HIV--EAD----
TOP1_ARCFU KDNTARRIASILFKD-VKTL-KKGRVSYY-HSPSNDAY-VVGLKG---HIV--ELD----
B5IE55_ACIB4 KRNAAQRIAKILSG-GRYETIKKGRNAYYSFTKGKDRYFVVPLRG---HIL--HMD----
B1L3G6_KORCO KPNVAKRIASILSE--GAKAKREGKVYYYEFDTGGERYYVAPAAG---HLL--ELD----
TOP1_AERPE KPKAAAKIAYALSDGRGVLRCSEYGVPYWIVRRDGAAIVVAPSAG---HLF--GPHT---
A3DP02_STAMF KPKAANKIALALSR--NPIRKSMYGIPYYLIKNRHSSIIVASAAG---HLY--GLHT---
B8D5I1_DESA1 KPKAAKKIASALSP--THNAKRIGSITIYEVDSYSSSIIIASSVG---HLY--QLHT---
K0IBM4_NITGG KPDAARRIAQALGD---PKESKPAGISVFDVANSDCHYKVCSALG---HLY--GLADSTK
TOP1_METTH KPKSSEKIAGALFP--DAMKKKHGKVSYWEHVEGDKRVTIVSAVG---HLY--SLRPRQS
F6D5C7_METPW KPKAAEKISSALSK--GAAKKHYKKVPYYEFEENGKKTTVLTAVG---HLY--SLAPKDK
TOP1_METJA KPSVAKKIANALGK---AKKKSIDGVPYYELERDGKKIIVASAVG---HLF--TLVEKEN
TOP1_PYRAB KPNVARKIAGALSE-RRPIRKTIFGVPYYEVFRDGKKLIVASAVG---HLY--GLAPKQ-
TOP1_PYRHO KPNVARKIAGALSE-RRPIKKSLFGVPYYEIFREGKKLIVASAVG---HLY--GLAPKR-
* *.
Q6F0G3_MESFL ----------------------------------WGLG---IDLQT--M-----TPTFKI
F0V2L5_MYCS3 --------------------------------GWLNFG---PDNFEIKWSNIERKISYEN
Q9PPP9_UREPA ----------------------------------KKSG---YDPKT--Y-----DLKWEI
TOP1_MYCGA ----------------------------------YTLG---FNTED--F-----VPKWEI
TOP1_MYCPN ----------------------------------KNFG---FNEAD--Y-----SPVWED
TOP1_MYCGE ----------------------------------KNFG---FDENT--Y-----TPIWED
Q3M6J7_TRIV2 ----------------------------------DALG---FSMDGGSV-----QCHYVP
Q4AA55_MESHJ ----------------------------------FGLG---IDINT--W-----TPSYVL
B3PMD8_META1 ----------------------------------DGLG---IDFTN--W-----EPMMIQ
TOP1P_MIMIV ----------------------------------KKMS---IDFDND-F-----EPVYIV
Q8F5G0_LEPIN ----------------------------------TTLG---LDLKNR-F-----EPEYVI
TOP1_BORBU EIPK-----------------------EYKKYEWANIS---IDYNNG-F-----NPIYII
H8H3H1_DEIGI DIPE-----------------------KYRDQAWARLG---INVDAG-Y-----APLYVS
B1VAJ5_PHYAS ----------------------------------DRLG---IDIKNG-F-----IPKYEI
TOP1_FERIS ----------------------------------KQFG---VDLNSL-------KLDFEI
TOP1_THEMA ----------------------------------SKFG---VDLEKD-F-----EPEFAV
B2V7T0_SULSY ----------------------------------NEMG---VDLNT--Y-----EPKFVI
TOP1_AQUAE ----------------------------------KELG---VDLRT--L-----KAKYVY
D3SM80_THEAH ----------------------------------DELG---VDLKT--L-----EPRYVF
G8QVT8_SPHPG ----------------------------------DRMA---IDVANG-F-----ACDYKT
TOP1_SYNE7 DIPT-----------------------ELKGEKWSNLG---VDVENN-F-----APLYIV
TOP1_SYNY3 EVPA-----------------------AYKDKSWANLG---VNVEDH-F-----SPLYVI
TOP1_STRCO EVPE-----------------------KYTGEV-RRLG---VDVEHD-F-----QPIYVV
TOP1_MYCTU DVPA-----------------------KYKSQPWARLG---VNVDAD-F-----EPLYII
TOP1_MYCLE DVPA-----------------------KFKSEPWARLG---VNVDAD-F-----EPLYII
I0II60_PHYMF KGSS-----------------------KEDQ---VLPG---VDLARN-F-----EPTYEI
J9Z7K0_LEPFM ----------------------------------SRLG---IDVDHD-F-----ALEFEV
TOP1_BUCAI YNKE---------KNKKFLNENFIEKTNENKILIKQMG---IDPYQN-W-----KFEYHI
TOP1_BUCAP KNKK--------------NIKKSNIKHNEKTALIQQMG---INPYKN-W-----KAEYHI
TOP1_PSEAE SSSK---EPAAKGRKSASEAPALSPKEKARRQLVSRMG---VDPEHG-W-----KAKYEI
TOP1_VIBCH TATPTGKAAAASTKKASTTDKEQQKREKERAALIKKMG---VDPYHG-W-----QANYQI
TOP1_ECOLI AAKK--------SADSTSTKTAKKPKKDERGALVNRMG---VDPWHN-W-----EAHYEV
TOP1_SALTY AAKK--------SADSTSTKTAKKPKKDERGALVNRMG---VDPWHN-W-----DAHYEV
TOP1_HAEIN STGE--KAKPISTKGMDAEEKAKIKAEKERNALVKRMG---IDPYHD-W-----KANYQI
TOP1_PASMU SNGE--KAKAISTKGLSAEEKSAIKQEKDRNALVKRMG---IDPYHQ-W-----KANYQI
TOP1_CAMJE ----------------------------------SSFG---IKIEDDEF-----IPEYRI
TOP1_HELPY ----------------------------------FALG---IKIDETGF-----TPNYVV
TOP1_HELPJ ----------------------------------FALG---IKIDETGF-----TPNYVV
TOP1_TREPA ----------------------------------SRLA---IDIEHD-F-----QPEYIT
TOP1_LACLA ----------------------------------STMS---VDIEND-Y-----EPQYIN
TOP1_STAS1 ----------------------------------SQMG---VDAEND-Y-----EPKYIT
TOP1_STAAB ----------------------------------SQMG---VDTEDN-Y-----EPKYIT
TOP1_STAA8 ----------------------------------SQMG---VDTEDN-Y-----EPKYIT
TOP1_STAAU ----------------------------------SQMG---VDTEDN-Y-----EPKYIT
TOP1_STAAM ----------------------------------SQMG---VDTEDN-Y-----EPKYIT
TOP1_STAHJ ----------------------------------SQMG---VDVEDN-Y-----EPKYIT
TOP1_STAES ----------------------------------SQMG---VDTEDN-Y-----EPKYIT
TOP1_BACSU ----------------------------------SQMG---VDIEQN-F-----EPKYIT
TOP1_HALH5 ----------------------------------SQMG---VDIEDE-Y-----SPRYIT
A5CVH7_VESOH ----------------------------------KNMG---IDIDNN-F-----TPTYEI
Q28MI5_JANSC ----------------------------------KDGS---VDPEEG-F-----FMKWEI
TOP1_XYLFT ----------------------------------KEGA---VDPENG-F-----AMRYDL
TOP1_XYLFA ----------------------------------KEGA---VDPENG-F-----AMRYDL
TOP1_RICTY ----------------------------------KKGS---VLPDKN-F-----AMEYDI
TOP1_RICPR ----------------------------------KKGS---VLPDKN-F-----LMEYDI
TOP1_RICBR ----------------------------------KKGS---VIPDEN-F-----SMKYDI
TOP1_RICFE ----------------------------------KKGS---VLPDEN-F-----AMKYDI
TOP1_RICCN ----------------------------------KKGS---VLPDEN-F-----AMKYDI
B7J7I8_ACIF2 A-----------------------------------AY---VRPPD--F-----KLNYEI
Q7WXW8_PSEAI DP--------------------------------QMLT---VGVGQD-F-----KPHYQI
C6XEP4_METGS ----------------------------------GEIG---YHPET--F-----EPIYEV
B1M9R9_METRJ ----------------------------------REFG---ISKPD--F-----SLQYEY
TOP1P_XYLFA ----------------------------------KEMG---VAAPD--F-----KPSYEL
C8W7T0_LANP1 FDKEEGWYGETAEGEHLPADVPDGLERPPYKVKRKPFMADGVDLKG--WKIP--SLPYLI
E1RJ15_METP4 -----------------------------------------FEPGYSNWRSETHTPKSLI
C7P1M5_HALMD -----------------------------------------FPPEYSDWR--DVEPAELV
TOP1_THEAC -----------------------------------------FESGYSDWN--KIDLSDLI
TOP1_ARCFU -----------------------------------------FPKELNNWT--K-TPLEKL
B5IE55_ACIB4 -----------------------------------------YPDEFKRWS--L-GDLQRL
B1L3G6_KORCO -----------------------------------------YPPGK--WEYPSIVPPERL
TOP1_AERPE ----------------------------------DSRG---FPVFDFEW-----RPIFEF
A3DP02_STAMF ----------------------------------DQYG---YPVFKYEW-----KPLYQI
B8D5I1_DESA1 ----------------------------------SLRG---YPVYSYEW-----IPLHLT
K0IBM4_NITGG ----------------------------------NRSV---YPVLDLEW-----APVDKN
TOP1_METTH N---------------------------------EEHF---FDLE---W-----APIHEI
F6D5C7_METPW KQ--------------------------------DKL----FDVE---W-----VPLYEK
TOP1_METJA ----------------------------------KEFGF--YPVFDIKW-----VPASVD
TOP1_PYRAB ----------------------------------DFFG---YPIFDIEW-----VPVYIA
TOP1_PYRHO ----------------------------------DVFG---YPIFDIEW-----VPVYIA
Q6F0G3_MESFL E-TT---------------------KKKNVSEIVKAGKSA-DKIILASDPDREGEAIAWH
F0V2L5_MYCS3 K------------------------KVSIIEAIKNEAKQA-SKIYLSTDPDREGEAIAWH
Q9PPP9_UREPA IKTTNK------------KLS----KKQQIKTIIDLAKKS-NNIYLATDPDREGEAISWH
TOP1_MYCGA IQEKKPAKGVSATKKAKTVKKAVKNKKEIIDELVDKAKKA-DEIYLATDPDREGEAISWH
TOP1_MYCPN W-TKSKKKFSSLSFKGNLKGKKLLSKYDIIKSIKEKASKA-TNIYLATDPDREGEAISWH
TOP1_MYCGE W-TKNKQK--------NPKQKHLLSKFEIIKSIKAKASDA-QNIFLASDPDREGEAISWH
Q3M6J7_TRIV2 RDQR---------------------SKETIQQLKSAAKQV-SEVVLATDPDREGETIAWH
Q4AA55_MESHJ D-KT---------------------KKKTIDEIKKLAKQA-KTVIIATDADREGEAIGAS
B3PMD8_META1 D-RT---------------------KAKVIKALKDATKNA-KEVLIATDPDREGEAIAQN
TOP1P_MIMIV T------------------------KPDVVKNLKSAMKNI-DLVYLAADEDREGEAIAQS
Q8F5G0_LEPIN L-PG---------------------KKKILSEIIKTAKQS-QKVFLATDPDREGEFISAY
TOP1_BORBU P-SN---------------------KKPIVSKLKKLVKTI-NEIYLATDQDREGETIAFH
H8H3H1_DEIGI --RA---------------------RTGVLTDLRAATKAAGGDVYLASDPDREGESIAWH
B1VAJ5_PHYAS I-KE---------------------KKTLVESLIKKTKN--KEIFLATDPDREGEAIAWH
TOP1_FERIS I-PG---------------------KESVVEQIKKMTSG--KEVLLPSDQDREGEAIAWH
TOP1_THEMA I-KG---------------------KEKVVEKLKDLAKK--GELLIASDMDREGEAIAWH
B2V7T0_SULSY KSQN---------------------HKKILSEIKKLAEK--SEVIIATDPDREGYAIGFF
TOP1_AQUAE K-RG---------------------KKKLVEQLKKLSRRS-SIVYLGTDPDREGEAIAYF
D3SM80_THEAH V-RG---------------------KRKVWDQIKRTAQKC-ESIYIGTDPDREGEAIAYF
G8QVT8_SPHPG V-EG---------------------KESLIRELKSSLKGV-DKLLLATDEDREGESISWH
TOP1_SYNE7 P-KD---------------------KKKIVKTLKDALKDA-DELILATDEDREGESISWH
TOP1_SYNY3 P-KS---------------------KKKVVKELQTALKNA-DEVILATDEDREGESISWH
TOP1_STRCO N-AD---------------------KKSQVKKLKDLLKES-DELFLATDEDREGEAIAWH
TOP1_MYCTU S-PE---------------------KRSTVSELRGLLKDV-DELYLATDGDREGEAIAWH
TOP1_MYCLE T-PE---------------------KKSTVTELKGLLQGV-DELYLATDGDREGEAIAWH
I0II60_PHYMF L-PD---------------------KKDTVSNLRKAAKVA-TDVYFATDLDREGEAIAWH
J9Z7K0_LEPFM H-PD---------------------KKKVLSEIRSEARSA-REVYLASDPDREGEAIAYH
TOP1_BUCAI L-PG---------------------KEKIISELKYIANQV-KHIYLATDLDREGEAIAWH
TOP1_BUCAP L-PG---------------------KEKIISELKNIANKV-HYIYLATDLDREGEAIAWH
TOP1_PSEAE L-PG---------------------KEKVIDELRRLAKDA-DTVYLATDLDREGEAIAWH
TOP1_VIBCH L-PG---------------------KEKVVAELQKLAKDA-DSVYLATDLDREGEAIAWH
TOP1_ECOLI L-PG---------------------KEKVVSELKQLAEKA-DHIYLATDLDREGEAIAWH
TOP1_SALTY L-PG---------------------KEKVVSELKQLAEKA-DHIYLATDLDREGEAIAWH
TOP1_HAEIN L-PG---------------------KEKVVSELKSLAKKA-DHIYLATDLDREGEAIAWH
TOP1_PASMU L-PG---------------------KEKVVAELKSLAKKA-DHIYLATDLDREGEAIAWH
TOP1_CAMJE T-SD---------------------HSALVKELKSKAKDA-KEVYLATDEDREGEAIAYH
TOP1_HELPY D-KD---------------------HKELVKQIIELSKKA-SITYIATDEDREGEAIGYH
TOP1_HELPJ D-KD---------------------HKELVKQIIELSKKA-SITYIATDEDREGEAIGYH
TOP1_TREPA V-RG---------------------RAQCLKELRTLSKQS-LQVFLASDRDREGEAIAYH
TOP1_LACLA I-RG---------------------KAPLINSLKKEAKAA-KAVYLASDPDREGEAISWH
TOP1_STAS1 I-RG---------------------KGPVVKELKKHAKKA-KKVFLASDPDREGEAIAWH
TOP1_STAAB I-RG---------------------KGPVVKELKKHAKKA-KNVFLASDPDREGEAIAWH
TOP1_STAA8 I-RG---------------------KGPVVKELKKHAKKA-KNVFLASDPDREGEAIAWH
TOP1_STAAU I-RG---------------------KGPVVKELKKHAKKA-KNVFLASDPDREGEAIAWH
TOP1_STAAM I-RG---------------------KGPVVKELKKHAKKA-KNVFLASDPDREGEAIAWH
TOP1_STAHJ I-RG---------------------KGPVVKDLKKYAKKA-KNVFLASDPDREGEAIAWH
TOP1_STAES I-RG---------------------KGPVVKDLKKHAKKA-KKIFLASDPDREGEAIAWH
TOP1_BACSU I-RG---------------------KGPVLKELKTAAKKA-KKVYLAADPDREGEAIAWH
TOP1_HALH5 I-RG---------------------KGPVLKELKSAAKKV-KRVYLAADPDREGEAIAWH
A5CVH7_VESOH T-AD---------------------KKKVVTDLRKAVKVA-EKVYLATDEDREGEAIAWH
Q28MI5_JANSC G-SD---------------------SKKHVKAIVDALKDD-NSLILATDPDREGEAISWH
TOP1_XYLFT I-DK---------------------NEKHVEAITKAAKTA-DSIYLATDPDREGEAISWH
TOP1_XYLFA I-DK---------------------NEKHVEAITKAAKTA-DSIYLATDPDREGEAISWH
TOP1_RICTY S-DK---------------------ASKYVDAIVKYARKA-EAVYLATDPDREGESISWH
TOP1_RICPR S-DK---------------------AGKYVDAIVKEARKA-EVVYLATDPDREGESISWH
TOP1_RICBR S-EK---------------------AGKYVDAIIKDAKKA-ESVYLATDPDREGESISWH
TOP1_RICFE S-DK---------------------AGKYVDAIVKDAKKA-DAVYLATDPDREGEAISWH
TOP1_RICCN S-DK---------------------AGKYVDAIVKDAKKA-DAVYLATDPDREGESISWH
B7J7I8_ACIF2 T-ER---------------------ASKTVPALRAAARDA-ESVYIATDPDREGEAIAWH
Q7WXW8_PSEAI L-SG---------------------KEKTVARLKELRQKA-VEIYVASDPDREGESIGWH
C6XEP4_METGS T-EK---------------------ARTTIKVLKAAVKEC-DRVLLATDPDREGEAISWH
B1M9R9_METRJ IPPQKV------------GNKTFPGAADRVARIKREVAKA-DAVYLATDPDREGEAISWH
TOP1P_XYLFA TERG----------------------EGVVAKLKNLLKQA-DSVYLATDPDREGEAISWH
C8W7T0_LANP1 WAPVDK------------QPA----EKEIIRALKNLAKKA-ESVIIGTDFDREGELIGSD
E1RJ15_METP4 D-AGTI------------KKPT---EKRIVQLIKRLAKKA-DHVIIATDFDREGELIGKE
C7P1M5_HALMD AADVVK------------SAT----QENIVATLRKLARRA-DEATIATDYDREGELIGKE
TOP1_THEAC DARIVK------------NIK----NKVAYQTLQAFRGKV-EEIVIATDYDREGELIGVE
TOP1_ARCFU LQAELV------------KKVK---ERTISSILKEIAKKA-DRVTVATDYDREGELIGVE
B5IE55_ACIB4 VDEEPI------------KIIK---EKGIANILRTLAKDA-DMLIIATDYDREGELIGVE
B1L3G6_KORCO VLKEIK------------G------KREYLKILEKLGKLS-NRIIVATDLDSEGSSIALE
TOP1_AERPE D-RGAG------------Y------LSKFYRMLSRILPGA-SLYVNACDYDIEGSVIGFK
A3DP02_STAMF D-PKAK------------H------TEKFIMVLSKLCSNA-DYYVNACDYDIEGSVIGYL
B8D5I1_DESA1 D-PSKK------------Y------IREYLEVLGKLCRGV-DYYVNACDYDIEGSVIGYL
K0IBM4_NITGG --PR---------------------AARAIKVISELSKNA-SAFVHACDYDQEGEVIGHN
TOP1_METTH DKKKGY-------------------VKDYLNVIRKFAAGA-DRYIHACDYDIEGTLIGFN
F6D5C7_METPW DKKKKY-------------------VKNYIDAIKKLSKDA-DTFVHACDYDIEGTLIGYN
TOP1_METJA KGKEY--------------------VNKYIKALKKLSKDA-DEFYIATDWDIEGELIGYH
TOP1_PYRAB E-KNKD------------Y------AKDYIKALSVLAKRV-KEFIVACDYDTEGEVIGYT
TOP1_PYRHO E-KGKE------------Y------AREYIKALSVLAKRV-REFIVACDYDTEGEVIGYT
: * * ** *.
Q6F0G3_MESFL -LANLFA-----KDNKEIKRITFNEITESAVVKAFGE--MR-EI-DIDLVNAQLSRQMLD
F0V2L5_MYCS3 -IYSILG----KEHQKKCSRAVFNEITESAVKYSLEN--TR-QL-DQAQINSYLARVLLD
Q9PPP9_UREPA -VYDLLP----KKDKERVKRITFNEITQKAILKSIDE--KH-DI-DFNLVDSQFARRILD
TOP1_MYCGA -VYDVLK--EKGVNVNKCKRIIFNEISEKAVKNAIAN--PR-EI-QKDWVSSQITRRRLD
TOP1_MYCPN -VYDVLD----EKDKSKCQRITFNEITKNAVLDALKN--PR-EI-DQSWVQSQFARQILD
TOP1_MYCGE -VYDLLD----QKDKAKCKRITFNEITKKAVVDALKQ--PR-NI-DLNWVESQFARQILD
Q3M6J7_TRIV2 -LKEVLG-------LREPKRVVYTEITASAVQSAIAH--PR-KL-DLNLVGAGLCRDCLD
Q4AA55_MESHJ -LVEHLA------ITDKYQRIKYNEITKTAILEALEN--PG-EL-NQNLINSQQTRRMLD
B3PMD8_META1 -LVDTLK------LSKIYRRIKYNEITAEAIKEALEN--PQ-MI-DDNLVKAQKTRRMLD
TOP1P_MIMIV -LYDVLK-------PSNYKRLRFNAITKDAIMSAIKN--AG-DI-DKNLVDAQKARRVLD
Q8F5G0_LEPIN -IRDRLQ------KKSNVFRIRFTEVTKQAILNSLQN--PD-TI-NEFLVDAQKTRRIGD
TOP1_BORBU -LKEVLK-------IKNYKRMIFHEITETAITESLKN--TR-NI-DMNLVNAGEARRILD
H8H3H1_DEIGI -LSVVLG-------LKDARRVTYQEVTKTAIQKALQN--PR-PI-NLALVAAQESRRILD
B1VAJ5_PHYAS -LSKVLN-----LNPQMANRIVFREITKEVVLKALQN--PR-TV-DELLVFSQETRRMLD
TOP1_FERIS -LSTILG-------VKGKNIITFTEITERAIKEAVKN--PR-EI-DMNKVNAQLARRVLD
TOP1_THEMA -IARVTN------TLGRKNRIVFSEITPRVIREAVKN--PR-EI-DMKKVRAQLARRILD
B2V7T0_SULSY -MYEELK-----KKAKEVKRAEFHEITKEHIKEKIKNAVPF-EKTNFGLFNAFLGRRVGD
TOP1_AQUAE -LKKDLE-----KVNKNIKRAVFYEITPEAIRESIRN--AG-DV-NMNLVYAQFARRILD
D3SM80_THEAH -LWNLLK-----PLGKKLYRVRFYEVSKEAITLSVQK--PE-DSPNMNLVRAQMARRVLD
G8QVT8_SPHPG -LLEVLK------PKIPYQRMVFHEITKGAIQKALES--GR-DL-DLNLVQAQEGRRIVD
TOP1_SYNE7 -LLQLLQ------PRVPTKRMVFHEITQEAIQAALKN--CR-DV-DQRLVHAQETRRILD
TOP1_SYNY3 -LLQLLQ------PKVPIKRMVFHEITQEAIRSALEN--CR-DI-DENLVHAQETRRILD
TOP1_STRCO -LQEVLK------PKIPVKRMVFHEITKDAIRAAVAN--PR-EL-NQKLVDAQETRRILD
TOP1_MYCTU -LLETLK------PRIPVKRMVFHEITEPAIRAAAEH--PR-DL-DIDLVDAQETRRILD
TOP1_MYCLE -LMQTLK------PRVPVKRMVFHEITEHAILAAAAH--PR-EL-DIDLVDAQETRRILD
I0II60_PHYMF -LAEALK-----VPTDQAKRVVFNAITKSALEEAFAR--PR-GI-AIPRVDAQQTRRILD
J9Z7K0_LEPFM -IASELE-----ALPVPPKRVLFHELTEGGIRSALSE--PG-EI-DVRKVEAQKARRALD
TOP1_BUCAI -LKEVIG-----GDSSKFSRVVFNEITQHSIQKAFKN--VG-HI-NMNRVHAQQARRFMD
TOP1_BUCAP -LKEVIG-----GNSLKFRRVVFNEITKKSIEKAFQN--IG-KI-NMNRVYSQQARRFMD
TOP1_PSEAE -LREAIG-----GDESRYKRVVFNEITKKAIQEAFSQ--PG-EL-DINRVNAQQARRFLD
TOP1_VIBCH -LREIIG-----GDEKRYKRVVFNEITKNAIQQAFKQ--PG-EL-NMDGVNAQQARRFMD
TOP1_ECOLI -LREVIG-----GDDARYSRVVFNEITKNAIRQAFNK--PG-EL-NIDRVNAQQARRFMD
TOP1_SALTY -LREVIG-----GDDARYSRVVFNEITKNAIRQAFEQ--PG-EL-NINRVNAQQARRFMD
TOP1_HAEIN -LREVIG-----GNDDRFSRVVFNEITKNAIKQAFEK--PE-QL-NMDRVNAQQTRRFLD
TOP1_PASMU -LREVIG-----GDDARFSRVVFNEITKNAIQQAFEK--PE-QL-NLDRVNAQQTRRFLD
TOP1_CAMJE -IAKAIG-----KDENTLPRIVFHEITKSAIENALKN--PR-KL-NMHSVNAQQTRRLLD
TOP1_HELPY -VACLIG-----GKLESYPRIVFHEITQNAILNALKT--PR-KI-DMSKVNAQQARRFLD
TOP1_HELPJ -VACLIG-----GKLESYPRIVFHEITQNAILNVLKT--PR-KI-DMFKVNAQQARRLLD
TOP1_TREPA -LAQSIQ----AYCDTPIKRIVFNEITPHAIRAAIGH--PV-PI-DTAKVNAQKARRVLD
TOP1_LACLA -LAHILN-----LPLEEKNRVVFNEITKDAVKNAFKE--PR-QI-DVDLVDAQQARRVLD
TOP1_STAS1 -LANILN-----LEDSTENRVVFNEITKDAVKDSFKH--PR-GI-EMELVDAQQARRILD
TOP1_STAAB -LSKILE-----LEDSKENRVVFNEITKDAVKESFKN--PR-EI-EMNLVDAQQARRILD
TOP1_STAA8 -LSKILE-----LEDSKENRVVFNEITKDAVKESFKN--PR-EI-EMNLVDAQQARRILD
TOP1_STAAU -LSKILE-----LEDSKENRVVFNEITKDAVKESFKN--PR-EI-EMNLVDAQQARRILD
TOP1_STAAM -LSKILE-----LEDSKENRVVFNEITKDAVKESFKN--PR-EI-EMNLVDAQQARRILD
TOP1_STAHJ -LSKILE-----LDDSKENRVVFNEITKDAVKESFKH--PR-GI-EMDLVDAQQARRILD
TOP1_STAES -LSKILE-----LEDSKENRVVFNEITKDAVKDSFKH--PR-GI-EMDLVDAQQARRILD
TOP1_BACSU -LAHSLD-----LDLNSDCRVVFNEITKDAIKESFKH--PR-MI-NMDLVDAQQARRILD
TOP1_HALH5 -LAHSLD-----IDETSECRVVFNEITKQAIKDAFKS--PR-PI-NMDLVDAQQARRVLD
A5CVH7_VESOH -LLEALN------LPKDTPRIVFHEITKNAITHAISE--PR-IV-NYRLVDAQQARRIID
Q28MI5_JANSC -LQEALTSRKAIKTDTPVSRVTFNAITKDAVTKAMAE--PR-QV-DMELVEAYLARRALD
TOP1_XYLFT -ISEILK-ERGLLKDKPMQRIVFTEITPRAIKEAIQK--PR-MI-ASDLVDAQQARRALD
TOP1_XYLFA -ISEILK-ERGLLKDKPMQRIVFTEITPRAIKEAIQK--PR-MI-ASDLVDAQQARRALD
TOP1_RICTY -VAEVIKEKNKVESDDFFKRVAFNEITKKAIIHAVEN--PR-KL-DTNLVNAQQARRALD
TOP1_RICPR -VAEVIKEKNKVESDDFFKRVAFNEITKKAIMNAVAN--PR-KL-DTNLVNAQQARRALD
TOP1_RICBR -IAEVIKEKNKVKSDDFFKRVAFNEITKKAITHAIEN--PR-KL-DNNLVNAQQARRALD
TOP1_RICFE -VAEVIKEKNKVKSDDFFKRVAFNEITKKAIIHAVEN--PR-KL-DANLVNAQQARRALD
TOP1_RICCN -VAEVIKEKNQVKSDDFFKRVAFNEITKKAIIHAVEN--PR-KL-DTNLVNAQQARRALD
B7J7I8_ACIF2 -VCQVLG-----IKPGAAKRVTYQEVTEPAIRKAIAA--PR-TV-NMPLVAAQEARRALD
Q7WXW8_PSEAI -ILQAAG-------IKNYKRVAFKEITKSCITAELSS--PR-RL-DLPKVASQECRRVID
C6XEP4_METGS -LAELLG-------LRKRERVKFHEITASAILKAINT--PS-AI-DTSLVRAQEARRIID
B1M9R9_METRJ -LKEALQ-----LGEDDYERVTFTEITPKAIQAALRA--AR-RI-DMDLVHAQEGRRALD
TOP1P_XYLFA -LQQCLK-------LSNPLRVTFNEITANAVKASLVA--PR-TI-DVKRVAAQEARRVLD
C8W7T0_LANP1 ALAQVLS----VNPNLAVFRARYSAFTKTEIETAFNN--LV-DL-DYNLAAAGESRQYID
E1RJ15_METP4 -AYEIVR---AANKTVPIKRARFSAITKQEITSAFAN--PA-EL-DFNLAEAGEARQVVD
C7P1M5_HALMD -AYELIR----EETDVPVDRVRFSSITDREVREAFAN--PD-EI-DFDLAAAGEARQVID
TOP1_THEAC -ALDIIK-----EGKEEIRRAKFSALTKNEILDSFKN--LI-GV-NYSLADAADARESID
TOP1_ARCFU -ALEIVK---SVNPTVKVDRVRYSAVTEKEIRSAFSK--PV-KV-DFNLANAALARQKID
B5IE55_ACIB4 -SLSITN------FKGPVKRAKFSALTEREIENAFSN--LV-DV-NYNLASAAETRQKID
B1L3G6_KORCO -IIKALN-----WEGKEILRMEFSSLTKEEIRSSFRD--LK-PF-DYPRAYAGWVRRVID
TOP1_AERPE -IIEAFG------DVNRARRMKFSTLAPQDIRRAYAR--ME-RL-DVEMIEAGMARSEMD
A3DP02_STAMF -IIYFHG------DLEKSLRAKFSSLTIEELRESFRK--LT-SL-DWEMIEAGLCRHELD
B8D5I1_DESA1 -IIKFNG------DERKAFRARFSSLTIEELRKAFNN--LT-RL-DYEMIEAGLCRHELD
K0IBM4_NITGG -ILQYAC----GGKYEKALRAKFSTLTDEEIRESFAS--LE-RP-SGGLAEAGRSRHMLD
TOP1_METTH -ALKYGC---GEEALRKTSRMKFSTLTREEIQRAYKN--PI-EV-DYGQVDSGAARHILD
F6D5C7_METPW -ALKYAC---GDESLKNVMRMKFSTLTDEDILKAYKK--PM-EL-DFKQVDSGIARHVLD
TOP1_METJA -ALKYCC------GREKAKRMRFSSLTKKEIVRAFEN--PD-EI-DYGLVDAGESRHILD
TOP1_PYRAB -ALKYAC----GVDPSRAKRMKFSALTKRDLLNAWRN--LEPTI-NFGMANAGIARHVLD
TOP1_PYRHO -ALKYAC----GVDPRVAKRMKFSALTKRDLLNAWRN--LEPTI-NFGMANAGIARHILD
: .: : : * *
Q6F0G3_MESFL KIIGYMVSNSLQKST-----GLL---SAGRVQTPALKILVDRDKIIKAFVETI----YKK
F0V2L5_MYCS3 RWIGFNLSSYVRKKV-----GGQ---SAGRVQSIALKFLADRDEEIKSFQPKN----WFI
Q9PPP9_UREPA RVIGYKLSGLVKKNL-----HGL---SAGRVQSIALLFVVERELERRSFVKEE----WYQ
TOP1_MYCGA RLIGFKLSSLMKSKI-----NAD---SAGRVQSIALKFITEREELINKFVPRF----WWT
TOP1_MYCPN RMIGFRLSRLLNNYL-----SAK---SAGRVQSVALRFLEEREQEIRSFVPRF----WWT
TOP1_MYCGE RMIGFRLSRLLNSYL-----QAK---SAGRVQSVALRFLEEREKEIAKFVPRF----WWT
Q3M6J7_TRIV2 KLVGYKGSPLVWALNN----GAK---SVGRVQSSTLHLICQREREIQSFVPQD----YWS
Q4AA55_MESHJ RIIGFRLTALLKNKIK----NPPKNPAAGRVQSFALSLIFDREKEIREFIPEK----YFN
B3PMD8_META1 RIIGFRLSQLMKRKVK----NAPSLPSAGRVQSIALKLVCDKEKEIKAFIPIK----YNK
TOP1P_MIMIV RLFGYLISPILQRQIG----GKL---SAGRVQSVTVRIIIDKENEIKNFINKNADSSYFK
Q8F5G0_LEPIN RLIGYFISPVLWKQIG----PGL---SAGRVQSVALKWICEREEEIRNFKIEI----YYN
TOP1_BORBU RLYGYTISPLLWKKVA----YGL---SAGRVQSVGLKLLIEKEKTRINFKKAN----YYS
H8H3H1_DEIGI RLAGYGVSPLLWDAIG----GPQ---SAGRVQSAALMLLAQREQSRLSFIPSA----YWR
B1VAJ5_PHYAS RIIGFKLSRLV-RRI-----KSQ---SAGRVQSVALKLIVDLEKEINSFVPEE----YNL
TOP1_FERIS RIVGYMISPLLWRIIK----DAR---SAGRVQSAALKIICERERERYRFVPQK----YFK
TOP1_THEMA RIVGYSLSPVLWRNFK----SNL---SAGRVQSATLKLVCDREREILRFVPKK----YHR
B2V7T0_SULSY RIVGYTLSPIASREIG----GRF---SVGRVQSPAVRLIVEREIEIQNFKPTP----YYV
TOP1_AQUAE RLIGYLISPILWKEFK---NYKL---SAGRVQSPALRLIVEREREIQNFKVKK----YYY
D3SM80_THEAH RLIGYLLSPKLWVYLK---NNRL---SVGRVQSPALRLIVERERQIRQFKKKK----FYY
G8QVT8_SPHPG RLYGYTLSPTLWKKLA---NKRL---SAGRVQSVGLRLTVERERQRIAFTKSS----YFD
TOP1_SYNE7 RLVGYTLSPLLWKKIA----WGL---SAGRVQSVAVRLLVQRERARRAFRQGS----YWD
TOP1_SYNY3 RLVGYTLSPLLWKKIA----WGL---SAGRVQSVAVRLIVQRERARRAFKTAG----YWD
TOP1_STRCO RLYGYEVSPVLWKKVM----PRL---SAGRVQSVATRLVVERERERIAFRSAE----YWD
TOP1_MYCTU RLYGYEVSPVLWKKVA----PKL---SAGRVQSVATRIIVARERDRMAFRSAA----YWD
TOP1_MYCLE RLYGYEVSPVLWKKVA----PKL---SAGRVQSVATRIIVQRERDRMAFCSAV----YWD
I0II60_PHYMF RIVGYQVSPLLWRKVA----GGL---SAGRVQSVATRLVVERERAIEAFVPEE----FWK
J9Z7K0_LEPFM RIVGYTISPLLWDRVR----RGL---SAGRVQSVAVRLVCDREDEIARFVREE----YWT
TOP1_BUCAI RIVGYMISPLLWKKIA----RGL---SAGRVQSVAVRIIADRESIIKNFVPEE----YWK
TOP1_BUCAP RIVGYMISPLLWKKIS----RGL---SAGRVQSAAVRLITDREYEIKNFIERE----HWK
TOP1_PSEAE RVVGYMVSPLLWQKIA----RGL---SAGRVQSVAVKLVVEREREIRAFVPEE----YWE
TOP1_VIBCH RVVGFMVSPLLWKKVA----RGL---SAGRVQSVAVKLLVEREREIKAFVPEE----FWD
TOP1_ECOLI RVVGYMVSPLLWKKIA----RGL---SAGRVQSVAVRLVVEREREIKAFVPEE----FWE
TOP1_SALTY RVVGYMVSPLLWKKIA----RGL---SAGRVQSVAVRLVVEREREIKAFVPEE----FWE
TOP1_HAEIN RVVGFMVSPLLWKKVA----RGL---SAGRVQSVAVKLLVEREREIKAFQPEE----YWE
TOP1_PASMU RVVGFMVSPLLWKKVA----RGL---SAGRVQSVAVKLVVEREREIKAFQPEE----YWE
TOP1_CAMJE RIVGYKLSPLLGQKIQ----RGL---SAGRVQSAALKIIVDREKEIRAFVPLE----YFS
TOP1_HELPY RIVGFKLSSLIASKIT----KGL---SAGRVQSAALKLVIDKEREIKAFKPLT----YFT
TOP1_HELPJ RIVGFKLSSLIASKIT----KGL---SAGRVQSAALKLVIDREKEIRPFKPLT----YFT
TOP1_TREPA RLVGYHLCPLLWHKVK----NGL---SAGRVQSVALRLICEREVEVKRFVPEE----YWT
TOP1_LACLA RLVGYSISPILWKKVK----KGL---SAGRVQSIALKLIVDRENEINAFIPEE----YWS
TOP1_STAS1 RLVGYNISPVLWKKVK----KGL---SAGRVQSVALRLVIDRENEIRNFKPEE----YWK
TOP1_STAAB RLVGYNISPVLWKKVK----KGL---SAGRVQSVALRLVIDRENEIRNFKPEE----YWI
TOP1_STAA8 RLVGYNISPVLWKKVK----KGL---SAGRVQSVALRLVIDRENEIRNFKPEE----YWT
TOP1_STAAU RLVGYNISPVLWKKVK----KGL---SAGRVQSVALRLVIDRENEIRNFKPEE----YWT
TOP1_STAAM RLVGYNISPVLWKKVK----KGL---SAGRVQSVALRLVIDRENEIRNFKPEE----YWT
TOP1_STAHJ RLVGYNISPVLWKKVK----KGL---SAGRVQSVALRLVIDRENEIRNFKPEE----YWS
TOP1_STAES RLVGYNISPVLWKKVK----KGL---SAGRVQSVALRLVIDRENEIRNFKPEE----YWS
TOP1_BACSU RLVGYKISPILWKKVK----KGL---SAGRVQSVALRLIIDREKEINDFKPEE----YWT
TOP1_HALH5 RLVGYNISPLLWKKVK----KGL---SAGRVQSVAVKMIIDREKEIQAFEPEE----YWS
A5CVH7_VESOH RLVGFEISPILWRKIS----GAR---SAGRVQSPVVRLVVEREREISKHIDNS----TYK
Q28MI5_JANSC YLVGFNLSPVLWRKLP----GAK---SAGRVQSVCLRLVVEREMEIEAFRPRE----YWS
TOP1_XYLFT YLVGFNLSPVLWRKVQ----RGL---SAGRVQSPALRMIVEREEEIEAFITRE----YWS
TOP1_XYLFA YLVGFNLSPVLWRKVQ----RGL---SAGRVQSPALRMIVEREEEIEAFITRE----YWS
TOP1_RICTY YLVGFTLSPLLWRKLP----GCK---SAGRVQSVALRLICDREDEIERFKAEE----YWD
TOP1_RICPR YLVGFTLSPLLWRKLP----GCK---SAGRVQSVALRLICDREDEIERFKSEE----YWD
TOP1_RICBR YLVGFTLSPLLWRKLP----GCK---SAGRVQSVALRLICEREDEIERFKSEE----YWD
TOP1_RICFE YLVGFTLSPLLWRKLP----GCK---SAGRVQSVALRLICEREDEIERFKSEE----YWD
TOP1_RICCN YLVGFTLSPLLWRKLP----GCK---SAGRVQSVALRLICEREDEIERFKSEE----YWD
B7J7I8_ACIF2 RIVGWEVSGPLSNAIG----SRA---SAGRVQTPALSLVVAREQAIRQFKPTP----WFQ
Q7WXW8_PSEAI RLVGYLVTPELRRVMG----RPT---TAGRVQSVAVYLVVLREREIRAFTAIK----HFG
C6XEP4_METGS RQVGWLVSGPLTRKIG----QRA---SAGRVQSPALALVVEREREILAFKKEA----FFT
B1M9R9_METRJ RFVGYMVSPLLSDMLG----MNL---SAGRVQSVAVRLVVDLERRIAAFKSTK----HFS
TOP1P_XYLFA RLVGYMVSPELSRLTG----KRL---SAGRVQSPAVRLVVEREREIKAFKVTN----HFG
C8W7T0_LANP1 LIWGAVLTRYLTTARFGGLGNTR---SAGRVQTPTLALVVERERERLAFKPED----YWV
E1RJ15_METP4 LIWGASLTRFISLAAKRGGNNIL---SVGRVQSPTLAMIVDREKEIEAFVPEP----YWM
C7P1M5_HALMD LVWGAALTRFLSLSARQLGDDFI---SVGRVQSPTLKLIVDREREIQAFDPED----YWE
TOP1_THEAC LIWGSVLTRFFSVTTGRLGKSFL---SAGRVQTPTLAIVVDREREIQSFRPER----YWT
TOP1_ARCFU LIWGATLTRLISVHSGRMGKDFL---SVGRVQTPTLRLIVDRELEIQNFKPEK----YYE
B5IE55_ACIB4 LAWGASLTRFISLASSRRGKDYL---SVGRVQSPTLALIVKREKEIENFVPTP----YWN
B1L3G6_KORCO LEWGANVSRGLTLSTR--RKGWVRVLSSGRVQGPTLSMIVKREREIREFVPKK----YYT
TOP1_AERPE WLWGINVSRALMEAARRAAGRRV-ILSAGRVQSPTLVEAYRRWREINLHVPKA----SVA
A3DP02_STAMF WIWGINISRALMSSVKIASGKRV-ILSAGRVQTPTLRYVVEKDIERRLFIPLP----QYS
B8D5I1_DESA1 WIWGINVSRALMKAVEDAVGERI-ILSAGRVQTPTLKYVVDKVVERNLFIPLP----QYN
K0IBM4_NITGG FIYGVNLSRALAQSLK-MASNGYCNLSIGRVQGPTLAFAVDRELEIRLHVPDP----YWT
TOP1_METTH FIFGVNISRSLMKSVKAATNRFI-KLSAGRVQTPTLAILVEREKEIRDFKPVP----YWI
F6D5C7_METPW FFFGVNMSKHLTDSVMKATKRYI-QLSAGRVQTPTLSILVDREKEIKEFIPVP----YWL
TOP1_METJA WYFGINLSRALMNAIR-AVNRWK-TMSVGRVQGPALAFLTERELEIKKFIPKP----YWV
TOP1_PYRAB WYWGVNLSRALTHAIKRASGKWV-VLSTGRVQGPTLKFLVEREREIQSFVPKP----YWV
TOP1_PYRHO WYWGVNLSRALTHAIKKASGKWV-VLSTGRVQGPTLKFLVEREREIQSFVPRP----YWV
* : **** .
Q6F0G3_MESFL IFVMDS-KQNVK---------------------------------LFLYKDDNNLVVNDP
F0V2L5_MYCS3 LKVQLQ-VGLTITLFK-----------------------------LSEAAESQVVLSPHG
Q9PPP9_UREPA IEGIIE-KNIFVSLRKIP---------------------------YDVELYNQKDNSDSD
TOP1_MYCGA LDVILK-DGTELMLRKIDEK-------------------------LKDKLGFKELEEVSG
TOP1_MYCPN LDVLLNPKAEGVREACANRS-------------------------IPIVLREINPALRAG
TOP1_MYCGE VDVLLN-KENNQKVVCANKSIPLVLRE------------------INPELSASLKLDFEA
Q3M6J7_TRIV2 VWVDYV-EG------------------------------------FRAFYKG----AVNT
Q4AA55_MESHJ LEVKIN-DENGN---------------------------------FFDTIYCNQQNEAKK
B3PMD8_META1 IQAKIS-ED------------------------------------VIADFYYPTNSDFKN
TOP1P_MIMIV VSGTFN-GAKATLHESNDKKP------------------------FDLETA------YKG
Q8F5G0_LEPIN ILLHGT-DQKG----------------------------------IVGIFSR-----TGD
TOP1_BORBU ILLQCK-HEKKNLL-------------------------------LEAKLEE-----IDG
H8H3H1_DEIGI VTASVG-TTPT----------------------------------FQASVQA-----IRG
B1VAJ5_PHYAS ITAFFP-F-------------------------------------FQAEYQN-----PNN
TOP1_FERIS VWIDIA-G-------------------------------------LKAYLTK-----VDG
TOP1_THEMA ITVNFD-G-------------------------------------LTAEID------VKE
B2V7T0_SULSY LSAVLRATSHVSPLT------------------------------FTAI--------YEN
TOP1_AQUAE VKALLR-KGSEE---------------------------------FWAIYDY-----RYE
D3SM80_THEAH IKAVFE-KNGHT---------------------------------FHLIWDY-----RFE
G8QVT8_SPHPG AKVDLL-SSDGQ------Q--------------------------FEAKLFS-----YQE
TOP1_SYNE7 LKAQLT-VEAGQ---------------------------------FEAKLWT-----LAG
TOP1_SYNY3 LKAELE-QNKNP---------------------------------FQAKLMT-----LGG
TOP1_STRCO LTGTFA-TGRAGDASDPSS--------------------------LVARLQT-----VDG
TOP1_MYCTU ILAKLD-ASVSDPDAAPPT--------------------------FSARLTA-----VAG
TOP1_MYCLE IVAKLD-ASVSDPTAQPLT--------------------------FVARLTA-----VDG
I0II60_PHYMF LTGFFT-PKMDEAKKLGDAWRDFLKKSGEDVTIKNQNGFLSENGVLRAELDT-----VGG
J9Z7K0_LEPFM IDARFR-PGDPRVPPT-----------------------------FLARLDR-----VSG
TOP1_BUCAI LDVSLI-SQDKKK--------------------------------INMDVTH-----YNN
TOP1_BUCAP ISLSLLSKENKK---------------------------------VTMDITH-----YRN
TOP1_PSEAE VHADLG-TAKGAN--------------------------------VRFEVTR-----EKG
TOP1_VIBCH INADTL-TADKQD--------------------------------FRLLVAQ-----KDG
TOP1_ECOLI VDASTT-TPSGEA--------------------------------LALQVTH-----QND
TOP1_SALTY IDANTT-TPSGEA--------------------------------LPLQVTH-----QND
TOP1_HAEIN VAVLTN-NQNKQA--------------------------------IRLDVTD-----YKG
TOP1_PASMU IDVLTQ-TQAKQA--------------------------------LRLAVTQ-----FKG
TOP1_CAMJE IDMIFQ-KD------------------------------------LDAELVE-----FDK
TOP1_HELPY LDAYFE-SH------------------------------------LEAQLIS-----YKG
TOP1_HELPJ LDALFE-PH------------------------------------LEAQLIS-----YKG
TOP1_TREPA VEGTFE-KDKKS---------------------------------FSALLIL-----IQG
TOP1_LACLA IDGEFK-KGTKK---------------------------------FKASFWG-----IDG
TOP1_STAS1 IEGEFR-YKKTK---------------------------------FTAKFLH-----FKN
TOP1_STAAB IEGEFR-YKKSK---------------------------------FNAKFLH-----YKN
TOP1_STAA8 IEGEFR-YKKSK---------------------------------FNAKFLH-----YKN
TOP1_STAAU IEGEFR-YKKSK---------------------------------FNAKFLH-----YKN
TOP1_STAAM IEGEFR-YKKSK---------------------------------FNAKFLH-----YKN
TOP1_STAHJ IEGEFR-YKKSK---------------------------------FTAKFLH-----YKN
TOP1_STAES IEGEFR-YKKSK---------------------------------FTAKFLH-----YKN
TOP1_BACSU IDGTFL-KGQET---------------------------------FEASFFG-----KNG
TOP1_HALH5 IQGTFA-LDGEP---------------------------------FEAKFYG-----TNG
A5CVH7_VESOH VKAELS-SESGEI--------------------------------FKVKLSK--------
Q28MI5_JANSC VRAVLE-TPRGQT--------------------------------IEARLTV-----LGG
TOP1_XYLFT IHAECT-HPAQH---------------------------------FSAKLIK-----LDG
TOP1_XYLFA IHAECA-HPAQH---------------------------------FSAKLIK-----LDG
TOP1_RICTY ISLKMQ-NSNNEL--------------------------------FTAKLTH-----VND
TOP1_RICPR ISLKMQ-NSNNDL--------------------------------FTAKLTH-----VND
TOP1_RICBR ISLKML-NSNNEL--------------------------------FTAKLTH-----IND
TOP1_RICFE ISLKMQ-NSNNEL--------------------------------FTAKLTH-----VND
TOP1_RICCN ISLKMQ-NSNNEL--------------------------------FTAKLTH-----VND
B7J7I8_ACIF2 VLAHVA-GKDAAPD-------------------------------WRAVWVD----GTQE
Q7WXW8_PSEAI VELTFV-SPSDGRT-------------------------------WTAEWDPVPVFASEE
C6XEP4_METGS VEAEFS-EE------------------------------------WGAVWPS------DE
B1M9R9_METRJ AVVTFDAGAGAK---------------------------------WSAQWDTKPYV-TED
TOP1P_XYLFA AMLFFA-DAKTSGE-------------------------------WSAEWLTKPKFVAED
C8W7T0_LANP1 ISGVASPEDDDEAT-------------------------------FKMV--------HQT
E1RJ15_METP4 ISLDSE-TEEEK---------------------------------FEAR--------HTE
C7P1M5_HALMD IFGDLQ-GDDAA---------------------------------FEAQYFY-----DDD
TOP1_THEAC ISITFD-KDGQ----------------------------------FKARYPE--------
TOP1_ARCFU IFAEFE------------------------------------------GFIA-----KHP
B5IE55_ACIB4 IKGLFF-KRRN----------------------------------FSGM--------HIS
B1L3G6_KORCO VIVKVD-KG------------------------------------FSLELAP-----PKG
TOP1_AERPE VKITAE-KGGGV---------------------------------FDARPHG-----WKP
A3DP02_STAMF LSINIF-KNN-----------------------------------YEIHVE------YKG
B8D5I1_DESA1 INITVE-KNGEK---------------------------------IRLE--------YTG
K0IBM4_NITGG IAAQFE-KNNQT---------------------------------FSAQYEK-----PKV
TOP1_METTH IRAELG-EG------------------------------------IIAE--------SKR
F6D5C7_METPW IKADLDVTGVKEG--------------------------------ITAD--------HKK
TOP1_METJA IEALLK-DN------------------------------------LKAI--------HEK
TOP1_PYRAB IKLVIE-KNGQK---------------------------------LVAN--------YEK
TOP1_PYRHO IKLIFE-KNGQK---------------------------------FTAN--------YEK
Q6F0G3_MESFL KNY------------------------YISEEQSKVIINNL-------------------
F0V2L5_MYCS3 KKG---------------------VVSFQKKEDLERIINDH-------------------
Q9PPP9_UREPA LKF-------------------------LHKKDAQRVIDDL-------------------
TOP1_MYCGA IDF-------------------------NTKEDAELVKQHL-------------------
TOP1_MYCPN LKF--------------EEEKSVSGIDFLDEASAKKFGEQL-------------------
TOP1_MYCGE AEN-------------------VSGIDFLNEASATRFANQL-------------------
Q3M6J7_TRIV2 RSDSPETEVEIHDDAAGNSTTAPESTRVLAEAEANRLVEEA-------------------
Q4AA55_MESHJ VNW------------------------INSEEELSEIIAEI-------------------
B3PMD8_META1 DNT------------------------WILPEKIDSIVAEL-------------------
TOP1P_MIMIV KTA--------------------QIALINSENPNSKVVNFM-------------------
Q8F5G0_LEPIN RIF--------------------------SKEKADQILQNV-------------------
TOP1_BORBU KNIAEGKDFVNETGKLKNIA----KTTIITQDLMIELEKEL-------------------
H8H3H1_DEIGI LPLATAASFTAQGQLKEGI-----EVAQLDAQKAEGLRAYL-------------------
B1VAJ5_PHYAS KKI--------------------------KSAEALGIVAKI-------------------
TOP1_FERIS KKI---------------------KPTDITEEISKDVLQKV-------------------
TOP1_THEMA KKF-------------------------FDAETLKEIQ----------------------
B2V7T0_SULSY PKI-------------------------ENKEEAEKIYADI-------------------
TOP1_AQUAE NP-----------------------------SDAKIIAKKL-------------------
D3SM80_THEAH KP-----------------------------ENAKPYLEKL-------------------
G8QVT8_SPHPG KSIAQSKDFDSVSGIYKGKA----SVLLLDKNQLHAIVQDL-------------------
TOP1_SYNE7 QRLATGNDFDESTGQIIAG----RQVCLLDQQEAEALRDRL-------------------
TOP1_SYNY3 TKLANGSDFDPNTGALLPD----KQVVVLDEAQAIALKERL-------------------
TOP1_STRCO RRVAQGRDFD-SLGQLKSAN-----TLHLDEANARALAAAL-------------------
TOP1_MYCTU RRVATGRDFD-SLGTLRKGD----EVIVLDEGSATALAAGL-------------------
TOP1_MYCLE LRVATGRDFG-AMGTLR-GDCEVSKIIVLDDLTATTLAAGL-------------------
I0II60_PHYMF RKW-----------------------KTDDREQALALAESLGFVLDDAVETEHPDEKGPA
J9Z7K0_LEPFM EKP-----------------------VLPDEETAGRTVERI-------------------
TOP1_BUCAI KKF-----------------------RPINENEVSFAVEKI-------------------
TOP1_BUCAP KTF-----------------------LLNNKKEVNSTIEKI-------------------
TOP1_PSEAE EAF-----------------------KPLNEAQAMAALEKL-------------------
TOP1_VIBCH LAF-----------------------KPVNETEALAAVAAL-------------------
TOP1_ECOLI KPF-----------------------RPVNKEQTQAAVSLL-------------------
TOP1_SALTY KPF-----------------------RPVNREQTLAAVSLL-------------------
TOP1_HAEIN KKF-----------------------DPKNQKEAQSAVDFL-------------------
TOP1_PASMU KKF-----------------------EPKNATQAQSAVDFL-------------------
TOP1_CAMJE AKI--------------------EKLTITNKDRAKLILEAC-------------------
TOP1_HELPY NKL--------------------KAQELIDEKKAQEIKNEL-------------------
TOP1_HELPJ NKL--------------------KAQELIDEKKAQEIKNEL-------------------
TOP1_TREPA KKA-----------------------VFKSKQEATSAIGLF-------------------
TOP1_LACLA KKH-----------------------PLKTNEDVIKVMERL-------------------
TOP1_STAS1 KPF-----------------------KLTEKADVEKITTQL-------------------
TOP1_STAAB KPF-----------------------KLKTKKDIEKITAAL-------------------
TOP1_STAA8 KPF-----------------------KLKTKKDVEKITAAL-------------------
TOP1_STAAU KPF-----------------------KLKTKKDVEKITTAL-------------------
TOP1_STAAM KPF-----------------------KLKTKKDVEKITAAL-------------------
TOP1_STAHJ KPF-----------------------KLKTKKDVEKVTAEL-------------------
TOP1_STAES KPY-----------------------KLNNKDDVQRITEAL-------------------
TOP1_BACSU KKL-----------------------PLNSEADVKEILSQL-------------------
TOP1_HALH5 KKV-----------------------ELKSEDDVNNVLAKL-------------------
A5CVH7_VESOH --------------------------EFKSKKQVLAFANIL-------------------
Q28MI5_JANSC KKL--------------------DRYDLPSAAEAGLAVQAV-------------------
TOP1_XYLFT KKF--------------------EQFTITDSDTAAAAQRRI-------------------
TOP1_XYLFA QKF--------------------EQFTITDSDTAAAAQRRI-------------------
TOP1_RICTY QKL--------------------KKFSIINEKEAKDLTRKL-------------------
TOP1_RICPR QKL--------------------KKFSIINEKEAKDLTQKL-------------------
TOP1_RICBR QKL--------------------EKFSITNDKEAKDLTEKL-------------------
TOP1_RICFE QKL--------------------EKFSIINEKDAKDLTEKL-------------------
TOP1_RICCN QKL--------------------EKFSIINEKNAKDLTKKL-------------------
B7J7I8_ACIF2 GEY------------------------FQDKAHAKALADAL-------------------
Q7WXW8_PSEAI FPY------------------------VQDRQLAELVGA---------------------
C6XEP4_METGS QQC-------------------------KDRSVAETIAESK-------------------
B1M9R9_METRJ SPY------------------------VLDEALAAKASQSR-------------------
TOP1P_XYLFA NPY------------------------FMDRDFAAAVAQ---------------------
C8W7T0_LANP1 ARF-------------------------WDQAEADTVYDVV-------------------
E1RJ15_METP4 GKF-------------------------WDKESAERSLKGT-------------------
C7P1M5_HALMD GSE---------------------AERVWDEATAESVYEDL-------------------
TOP1_THEAC --------------------------NIKDQDTAEKIYEAI-------------------
TOP1_ARCFU KRY-------------------------GSKEEAEKLFAKI-------------------
B5IE55_ACIB4 NPF-------------------------WKEEEAMEVYEKV-------------------
B1L3G6_KORCO EER------------------------IWDQDYARRAAESV-------------------
TOP1_AERPE QSL----------------------------ETARSIKSEL-------------------
A3DP02_STAMF KSV-------------------------ETKKNAKEIIDEI-------------------
B8D5I1_DESA1 NPV-------------------------EKERDARDIVEKI-------------------
K0IBM4_NITGG GTL----------------------------AEAKSIVSAC-------------------
TOP1_METTH GKI-------------------------FKRELVDSILEKC-------------------
F6D5C7_METPW GKI-------------------------LEKKDADAILVEC-------------------
TOP1_METJA EKF-------------------------WNEKEAKNVYEKI-------------------
TOP1_PYRAB DKI-------------------------WSEEEAKKIVTEV-------------------
TOP1_PYRHO DKI-------------------------WEEEEGKRIVLEV-------------------
Q6F0G3_MESFL ------------GE---DYKCTKYKA-KEFEVRSFK-PYSTASLLQDGFSKLRMSAA---
F0V2L5_MYCS3 -----------LDD---HYILEEIGEKKLETSSPPE-VLKTSTLFELAINKLGLKAE---
Q9PPP9_UREPA -----------SD----IFKVYSIDDLKITKGDVQL-PLTTDKLLQIASNNFGWSAN---
TOP1_MYCGA -----------SD----KYRVYAIDTPKLKSSYPKE-VYKTSTLQQDAINKLKWRSM---
TOP1_MYCPN -----------KG----VFEVYNIDETKHYSSSPNS-AYTTASLQKDAINKLGWSSK---
TOP1_MYCGE -----------TG----EYEVYFIDEPKIYYSSPNP-VYTTASLQKDAINKLGWSSK---
Q3M6J7_TRIV2 -----------RRH---PHQIVQYEG-KIANRQPPP-PFITSTLQQAAGSKLKFAPE---
Q4AA55_MESHJ -----------KEN---PYLIFKKYS-KATRKDPKVIPLKQATIFKKMSQ---YSSA---
B3PMD8_META1 -----------NKNK--SLLVKDFKV-SQRKESQIT-PFKQSVLYKEA----KYSAT---
TOP1P_MIMIV -----------KRCLKSQFFIHSVED-KMTTRSPAP-PFTTSTLQQEANRKFGMSID---
Q8F5G0_LEPIN -----------QKEK--EFRISEKKE-TLGKLFPPP-PFQTASLQQEAFKKLRFSSK---
TOP1_BORBU ----------KNGQ---KIELISIET-KKIKIPPPK-PFTTSTLQQEINKRLKIGTK---
H8H3H1_DEIGI -----------EGR---DAEITNIEV-SPITRRPPP-PFTTSSLQQAAGARLHLGVE---
B1VAJ5_PHYAS -----------TNK---PFIVKKIKQ-TETFSKPKK-PLITSTLQQEAINNLYMTSN---
TOP1_FERIS -----------K-----SVRLVDIDV-KEVRKNPPA-PFITSTLQQDAASKLGFPVS---
TOP1_THEMA -----------SID---ELVVEEKKV-SVKKFAPPE-PFKTSTLQQEAYSKLGFSVS---
B2V7T0_SULSY -----------KDEK--IATIKKVEK-KQVKQSPKP-PFTTSTLQQTASTVYRFAPE---
TOP1_AQUAE -----------EKG---YFSVYKVEK-KKEKVSPPK-PFITSDLQSEANAKFGFSSE---
D3SM80_THEAH -----------KSV---PFEVERVVR-GKVKKEPPK-PFHTANLQAVASQKLGVGVD---
G8QVT8_SPHPG -----------NGA---PYEIVDIQR-KPFLTRPNI-PFTTSTLQQDAIKKLHFSAS---
TOP1_SYNE7 -----------QTQ---PWQVKSLEE-KPTTRKPAP-PFTTSTLQQESNRKLRLSAR---
TOP1_SYNY3 -----------TGK---PWAVVNTEE-KPGVRKPSP-PFTTSTLQQEANRKLGISAR---
TOP1_STRCO -----------ENT---RFAVRSVES-KPYRRSPYA-PFRTTTLQQEASRKLGFGAK---
TOP1_MYCTU -----------DGT---QLTVASAEE-KPYARRPYP-PFMTSTLQQEASRKLRFSAE---
TOP1_MYCLE -----------RGA---QLTVASAEE-KLYTRRPYP-PFMTSTLQQEAGRKLRFSAE---
I0II60_PHYMF QKQVRFLGGIGNAP---DYKIQSVET-KRTKRRPAP-PFITSTLQQRASSYLGFNLK---
J9Z7K0_LEPFM -----------RRE---RFTVGEITR-ADKKRNPSP-PLTTSRLQQEAANRLRFSAK---
TOP1_BUCAI -----------QKS---SCIVKNYEE-KISYLKAPA-PFITSTLQQSASLRLGFSVK---
TOP1_BUCAP -----------KNL---SFIITDRKD-KIFKKKPPA-PLITSTLQQASNIDLGFSVK---
TOP1_PSEAE -----------KAS---AYSVAKRED-RPTSSRPSA-PFITSTLQQAASNRLGFGVK---
TOP1_VIBCH -----------NKA---QYEVCKRED-KPTTSKPSA-PFITSTLQQAASTRLGYGVK---
TOP1_ECOLI -----------EKA---RYSVLERED-KPTTSKPGA-PFITSTLQQAASTRLGFGVK---
TOP1_SALTY -----------EKA---RYSVLERED-KPTSSKPGA-PFITSTLQQAASTRLGFGVK---
TOP1_HAEIN -----------NVS---DYVVTDLET-KPTSSRPRA-PFITSTLQQTASTRLGFGVK---
TOP1_PASMU -----------QHA---DYVVSDLET-KPTHSRAKA-PFITSTLQQTASTRLGFGVK---
TOP1_CAMJE -----------KNE---VYSISDIES-KERKIAPPP-PFMTSTLQQSASNRLGFNPK---
TOP1_HELPY -----------EKE---SYAISSIVK-KSKKSPTPP-PFMTSTLQQSASSLLGFSPT---
TOP1_HELPJ -----------EKE---SYIISSIIK-KSKKSPTPP-PFMTSTLQQSASSLLGFSPT---
TOP1_TREPA -----------SQS---EARVSQIRS-FEKNVRPKQ-PFTTSTLQQCAANRLGFTSR---
TOP1_LACLA -----------DGP---DFNVDKVEK-KERRRNAPL-PYTTSSMQQDAANKLNFRTR---
TOP1_STAS1 -----------DGD---QFEVTKVTK-KEKTRYPAN-PFTTSTLQQEAARKLNFKAR---
TOP1_STAAB -----------DGD---QFEITNVTK-KEKTRNPAN-PFTTSTLQQEAARKLNFKAR---
TOP1_STAA8 -----------DGD---QFEITNVTK-KEKTRNPAN-PFTTSTLQQEAARKLNFKAR---
TOP1_STAAU -----------DGD---QFEITNVTK-KEKTRNPAN-PFTTSTLQQEAARKLNFKAR---
TOP1_STAAM -----------DGD---QFEITNVTK-KEKTRNPAN-PFTTSTLQQEAARKLNFKAR---
TOP1_STAHJ -----------DGD---KFEITNVNK-KEKTRNPAN-PFTTSTLQQEAARKLNFKAR---
TOP1_STAES -----------NGD---QFEITNVNR-KEKTRYPAH-PFTTSTLQQEAARKLNFKAR---
TOP1_BACSU -----------KGN---QYTVEKVTK-KERKRNPAL-PFTTSTLQQEAARKLNFRAK---
TOP1_HALH5 -----------KGD---QFHVDSVQK-KERKRNPVS-PFTTSSLQQEAARKLNFRAK---
A5CVH7_VESOH -----------LLA---NLTITSIEK-KPFKRSPKP-PFITSTLQQEAFQKLGFSVK---
Q28MI5_JANSC -----------SSR---KLSVSDVEA-KPANRNPSP-PFMTSTLQQEASRKLGMGAK---
TOP1_XYLFT -----------QQAAQGRLHITDVTN-KERKRRPAP-PFITSTLQQEASRKLGFTTR---
TOP1_XYLFA -----------QQVAQGRLHITDVTN-KERKRRPAP-PFITSTLQQEASRKLGFTTR---
TOP1_RICTY -----------KLQ---KFYVEKIEK-KQQKRQPQP-PFITSSLQQEAARKLGFSAK---
TOP1_RICPR -----------KLQ---KFYVEKIEK-KQQKRQPQP-PFITSSLQQEAARKLGFSAK---
TOP1_RICBR -----------KSQ---NFHVDKIEK-KQQKRQPQP-PFITSSLQQEAARKLGFSAK---
TOP1_RICFE -----------KSQ---NFHVDKIEK-KQQKRQPQP-PFITSSLQQEAARKLGFSAK---
TOP1_RICCN -----------KSH---KFHVDKIEK-KQQKRQPQP-PFITSSLQQEAARKLGFSAK---
B7J7I8_ACIF2 -----------PSM---ALKVTKAET-KPVRKPPAP-PFTTSSMQMDGARALKAPVD---
Q7WXW8_PSEAI ------------IR---NVIVETCID-SEETDAPPA-PFISSSLQMAAGNALKWSPD---
C6XEP4_METGS -----------------QFSVLEYDL-SKLHEDPPP-PFRTSKLLQAASVVLGFDPK---
B1M9R9_METRJ -----------------QFVVLESKT-EEKSERPPS-PLSTLGMLRAASTALKMSSA---
TOP1P_XYLFA ------------VK---AVVVKSFDE-SEAKRSPPP-PFTTSTMQQAASVTLGVDPK---
C8W7T0_LANP1 -----------KDQT--QATVVEIES-RSRKQQPPA-PFNTTSLQAAAAAE-GISPA---
E1RJ15_METP4 -----------KE----PLTVIDIKE-GTRADHAPT-PFDTTAYIVAAS-RLGLSAS---
C7P1M5_HALMD -----------AALD--AATVTSVRE-RTRTDAPPE-PFNTTAFISAAGS-LGYSAQ---
TOP1_THEAC -----------KGK---NGRVSSYTS-KEDHIRRPA-PFSTTEFLREAS-RIGIMPT---
TOP1_ARCFU ------------GE---TAKVEEFTR-RRMEENRPT-PFNTTEFLREASKFM--SPH---
B5IE55_ACIB4 -----------KDTK--SAKVLDFIQ-EDRKIRPPI-PFNTTEFLSEAT-KLGFSAA---
B1L3G6_KORCO -----------K-----DTLIARVKS-DERKLSPPP-PFDGTSLQVEVSAITGLTPRQIA
TOP1_AERPE -----------RKN---PWLAVEEVRSERSILRPPP-AFNLGDLQKEANRILGLPPL---
A3DP02_STAMF -----------KRTG--YLIVKKYEE-KIYTLNPPP-AFNLGDLQEEAARIYGFSPY---
B8D5I1_DESA1 -----------RGYK--YLIVSKVEK-KHHILHPPP-PFNLGDLQKEAARLYGFSPA---
K0IBM4_NITGG -----------IGR---DGTVSDVVD-SKAVLGPPT-PFNIGDLQREAYRLFKLGPG---
TOP1_METTH -----------QGS---DAEVKDVRV-RDTIRKPPV-PFDLGTLQSEAYRVFGFSPK---
F6D5C7_METPW -----------KGK---DAVITEVNL-RKTTKTPPF-PFDLGSLQSEAYGVFGFSPR---
TOP1_METJA -----------KDEK--SAKVVEIKK-TKRKLKPLP-PFDLGTLQREAYSYFKISPK---
TOP1_PYRAB -----------KKS---KARVSNIEV-KRQKRNPPV-PFDLGTLQREAYSAFGFSPK---
TOP1_PYRHO -----------KKS---IPRVSNVEI-KRQKRTPPH-PFDLGTLQREAYSAFGFSPK---
Q6F0G3_MESFL -QITVAAQKLYE----------AGLVTYIRTDSNRYSS--DFVL--EAKNFIN--KNFKG
F0V2L5_MYCS3 -DVRRVAQSLYEGINLGGET--ISLITYPRTDRSSVSE--EFLK--LVKKFIL--KEYGE
Q9PPP9_UREPA -KTTLIAQQMFEGLEINNQQ--LALITYPRTDSERLSD--DFLQ--EANAFIE--NNFGK
TOP1_MYCGA -KITSVAQELYEGVTIDDEQ--IALISYPRTDSTRLSP--EYGK--TVLDFVA--KTYGK
TOP1_MYCPN -KVTLIAQHLYEGVSINGEQ--TALISYPRTDSTRLSA--QFQQ--SCKEYIL--NHYGE
TOP1_MYCGE -KVTMVAQRLYEGISVNGKQ--TALISYPRTDSIRISN--QFQS--ECEKYIE--KEFGS
Q3M6J7_TRIV2 -KTMQLAQKLYE----------AGLITYMRTDSVMLSP--EFCE--SARQWLE--QNDPQ
Q4AA55_MESHJ -SVSNALQKLYEGYGD------YGLISYPRTDSTRLSQ--TFIE--KGKEFII--KNFGP
B3PMD8_META1 -TVQISAQKLFE----------MGLISYPRTDSTRMSD--TFIA--KAREYIK--EKFGE
TOP1P_MIMIV -STMKTAQKLYE----------GGYITYMRTDSVEISA--EGHR--DIKKIIT--DQYGA
Q8F5G0_LEPIN -KTMSLSQRLYEGMDL-GNGQRNGLITYMRTDSVRLSS--EFVE--RARSWIL--SELGE
TOP1_BORBU -QIMQHAQKLYE----------HGYITYMRTDSHNIAK--IAKD--KITKIIK--NKYGK
H8H3H1_DEIGI -TVTRAAQSLYE----------QGLITYIRTDSPALSD--EALQ--LARAAVA--ERFGE
B1VAJ5_PHYAS -QTMRVAQKLYEGIDIEGES--IGLITYMRTDSPRFSE--VFVK--DAQKLIK--EKYGQ
TOP1_FERIS -KTMKIAQELYEGVD--TKEGHTAFITYMRTDSTRVSD--VAKE--AAEKFIL--KNFGR
TOP1_THEMA -KTMMIAQQLYEGVE--TKDGHIAFITYMRTDSTRVSD--YAKE--EARNLIT--EVFGE
B2V7T0_SULSY -KTMMLAQDLFE----------SGLITYHRTDSVRISE--KAID--GIRNLIN--KEFGK
TOP1_AQUAE -RTQKLAQELYE----------KGYITYPRTDSYRMNE--KKAK--EFMNYIE--KKYGK
D3SM80_THEAH -KVQKLAQKLYE----------EGFITYPRTDSLRMDE--KKAQ--EFMNYIK--KTLGE
G8QVT8_SPHPG -DTMRIAQKLYE----------NGFITYMRTDSPALSS--EGTQ--AARLLVK--QLYGP
TOP1_SYNE7 -ETMRVAQSLYE----------RGFITYMRTDSVHLSQ--QAIE--AARSCVE--QMYGK
TOP1_SYNY3 -DTMRVAQKLYE----------EGYITYMRTDSVHLSD--QAVT--AARNCVQ--QMYGK
TOP1_STRCO -STMQVAQKLYE----------NGYITYMRTDSTTLSD--TAVS--AARAQVT--QLYGA
TOP1_MYCTU -RTMSIAQRLYE----------NGYITYMRTDSTTLSE--SAIN--AARTQAR--QLYGD
TOP1_MYCLE -RTMSIAQRLYE----------NGYITYMRTDSTTLSE--SAIN--AARTQAR--QLYGE
I0II60_PHYMF -RTMRVAQQLYEGIDLKGSRGQTGLITYMRTDSTFLSG--EAIG--AARGYIE--DKLGK
J9Z7K0_LEPFM -KTMTVAQKLYEGVDL-PGQGPVGLITYMRTDSVRVSP--EAAE--AARSWIR--QNHPD
TOP1_BUCAI -KTMFLAQKLYE----------EGYITYMRTDSNYLSE--YAIK--KVRKYIK--SNYGS
TOP1_BUCAP -KTMFLAQKLYE----------QGYITYIRTDSYFLSN--YAIE--KVRSYIE--NFYGS
TOP1_PSEAE -KTMMMAQRLYE----------AGYITYMRTDSTNLSA--DAIG--MVRGFIE--DEFGQ
TOP1_VIBCH -KTMMLAQRLYE----------AGYITYMRTDSTNLSA--EAVE--NLRGYIT--KHYGE
TOP1_ECOLI -KTMMMAQRLYE----------AGYITYMRTDSTNLSQ--DAVN--MVRGYIS--DNFGK
TOP1_SALTY -KTMMMAQRLYE----------AGYITYMRTDSTNLSQ--DAVN--MVRGYIG--DNFGK
TOP1_HAEIN -KTMMLAQRLYE----------AGYITYMRTDSTNLSQ--DALN--MARTYIE--NHFGA
TOP1_PASMU -KTMMLAQRLYE----------AGYITYMRTDSTNLSQ--DALK--MVRGYIQ--SHYGE
TOP1_CAMJE -KTMMIAQKLYEGVN--THEGVMGVITYMRTDSLNLAK--EAVE--NARKFIQ--ANFGK
TOP1_HELPY -KTMSIAQKLYEGVA--TPQGVMGVITYMRTDSLNIAK--EALE--EARNKIL--KDYGK
TOP1_HELPJ -KTMSIAQKLYEGVA--TPQGVMGVITYMRTDSLNIAK--EALE--EARAKIL--KDYGK
TOP1_TREPA -KTMQVAQQLYEGVSL-GTH-RVGLITYMRTDSVRVSE--AAVK--EVRAWIA--THFSD
TOP1_LACLA -KTMMVAQQLYEGLTL-GSQGHQGLITYMRTDSTRISP--VAQS--AAHNYIA--DQFGE
TOP1_STAS1 -KTMMLAQQLYEGIDL-KKQGTVGLITYMRTDSTRISD--QAQS--EAKNYIQ--ETYGN
TOP1_STAAB -KTMMVAQQLYEGIDL-KKQGTIGLITYMRTDSTRISD--TAKA--EAKQYIT--DKYGE
TOP1_STAA8 -KTMMVAQQLYEGIDL-KKQGTIGLITYMRTDSTRISD--TAKV--EAKQYIT--DKYGE
TOP1_STAAU -KTMMVAQQLYEGIDL-KKQGTIGLITYMRTDSTRISD--TAKA--EAKQYIT--NKYGE
TOP1_STAAM -KTMMVAQQLYEGIDL-KKQGTIGLITYMRTDSTRISD--TAKA--EAKQYIT--DKYGE
TOP1_STAHJ -KTMMLAQQLYEGIDL-KRQGTVGLITYMRTDSTRISQ--TAKD--EAKQYIE--DKYGK
TOP1_STAES -KTMMLAQQLYEGIDL-KRQGTVGLITYMRTDSTRIST--SAKS--EAQQYIN--DKYGE
TOP1_BACSU -KTMMIAQQLYEGIDL-GREGTVGLITYMRTDSTRISN--TAVD--EAAAFID--QTYGK
TOP1_HALH5 -KTMMLAQQLYEGIDL-GKEGTVGLITYMRTDSTRISD--TAKA--ETKEYIE--SKFGK
A5CVH7_VESOH -QTMILAQNLYR----------KGFITYMRTDSFILSE--TAIE--AVHKIIV--REFGS
Q28MI5_JANSC -QAMSTAQRLYE----------AGHITYMRTDGIDMAP--EAVE--DARGAIK--TRYGV
TOP1_XYLFT -KTMQIAQKLYEGIAL-GEEGSVGLITYMRTDSVNLSL--DALS--EIRDIIA--RDYGT
TOP1_XYLFA -KTMQIAQKLYEGIAL-GEEGSVGLITYMRTDSVNLSL--DALS--EIRDIIA--RDYGT
TOP1_RICTY -KTMQIAQKLYEGVDI-GKE-TIGLITYMRTDGVTLSN--DAIA--DIRKLID--KNYGN
TOP1_RICPR -KTMQIAQKLYEGVDI-GKE-TIGLITYMRTDGVTLSN--DAIA--DIRKLID--KNYGN
TOP1_RICBR -KTMQIAQKLYEGVDI-GKE-TIGLITYMRTDGVTLSN--DAVD--EIRKLIN--KDYGD
TOP1_RICFE -KTMQIAQKLYEGVDI-GKE-TIGLITYMRTDGVTLSN--DAIA--DIRKLID--KNYGD
TOP1_RICCN -KTMQIAQKLYEGVDI-GKE-TIGLITYMRTDGVTLSN--DAIA--DIRKLID--KSYGD
B7J7I8_ACIF2 -AIMKAAQSLFE----------HGHITYHRTDSPNLSE--EGEG--LLRAALK--KE-NL
Q7WXW8_PSEAI -KTMKVAQRLYE----------QGLITYHRTDNPNISK--DSMP--DIRAVA---KALGL
C6XEP4_METGS -RTMDLAQSLFQK---------HGAISYHRTDESNISD--DAYG--MIVEYGQE-RNYPM
B1M9R9_METRJ -ATTKAAQKLFE----------DGHITYIRTDSVNLSP--DAAD--KVRSFAA--SQ-GM
TOP1P_XYLFA -AAMDAAQKLYE----------QGHITYHRTDNPNVSD--ESLG--DIYAVSV---KLGL
C8W7T0_LANP1 -RTMRLAESLYM----------DGLISYPRVDNTVYPSSLDLKD--CVRTLSAV-PQYAP
E1RJ15_METP4 -NAMRIAEELYM----------NGYISYPRTDNTIYPSSLDLKG--ILTELKK--SPFKR
C7P1M5_HALMD -RAMSLAEELYT----------AGYMTYPRTDNTVYPEDLEPDE--LLDEFVGS-STFGE
TOP1_THEAC -KAMSIAENLYM----------RGLISYPRTDNTVYPRSINLKS--VLKKLEN--TAYSK
TOP1_ARCFU -KAMNIAETLYM----------NGYISYPRTDNTVYPPTINLIE--IVSALS---SVFPR
B5IE55_ACIB4 -RAMRLAEELYM----------GGYISYPRTDNTVYPKTLSINS--ILKSLEK--SKFKE
B1L3G6_KORCO DRTSGIAQKLYE----------AGLISYIGTESQKYPKSWKKKDFVDMVKLIASYSPLKE
TOP1_AERPE -RTQSIAEELYL----------EALISYPRTNSQKLPPSINYRA--ILDKLAH--GPLGR
A3DP02_STAMF -KTQSIAEKLYL----------DALISYPRTNSQKLPPTLNYKA--IMNKLSRI-NNYKE
B8D5I1_DESA1 -ETQSIAEQLYL----------DALISYPRTNSQKLPPTLDYRR--ILENISSI-KSYRN
K0IBM4_NITGG -YTLAIAEKLYL----------QALISYPRTSSQKLPPSIGYGK--IISSLSRI-GGYGQ
TOP1_METTH -KTQTIAQNLYT----------EGYTSYPRTSSQKLPESIGYEK--ILKNLAKN-PRFGV
F6D5C7_METPW -KTQQIAQNLYT----------EGYTSYPRTSSQKLPKSIGYDK--ILKKLSYS-SAFGN
TOP1_METJA -ETQEIAQKLYE----------NALISYPRTSSQKLPKDRKYLE--DILNIIKNHPVYGK
TOP1_PYRAB -KTLDIAQSLYE----------KGFTSYPRTESQKLPKNLNFRL--IIQNISRM-PQYRP
TOP1_PYRHO -KTLDIAQSLYE----------KGFSSYPRTESQKLPRNINFRM--IIQNLAKM-PQYRP
: :: . :* ..
Q6F0G3_MESFL D---LF------KE----AVPVRTQANA---QEAHE-SIRPT-DLNQRPENISSQIE---
F0V2L5_MYCS3 T---YWVEEG--TL----KKKSIMGKKEIFIQGAHE-GIRPT-DVELTPQKLSKLLST--
Q9PPP9_UREPA E---YLENF---KN----KKINRKEVNI---QDAHE-AIRPV-DINLKPEEIKDYVSL--
TOP1_MYCGA D---YVATQSQLNG----ETKANKKQKA-KVQDAHE-AIHPI-DISITPDSVKNKISS--
TOP1_MYCPN K---YLS-----NR----IVSAKGKKGEKIIQDAHE-AIHPT-DINITPEMVKNAIKK--
TOP1_MYCGE H---YLADKN--KL----KRHKKDEKII---QDAHE-GIHPT-YITITPNDLKNGVKR--
Q3M6J7_TRIV2 N----VP-----KQ----VARHRSSKTA---QQGHE-AIRPT-DVFRPSAQLRIELST--
Q4AA55_MESHJ K---YFT-K---SI----KGF----AGD---QDAHE-AIRPT-NLELSPELAREKYHLGQ
B3PMD8_META1 N---YVA-S---DI----KSF----SGA---QDAHE-AIRPT-DIYLIPQVAKTKYDLGE
TOP1P_MIMIV D---YY------QK----NLYKNKAANS---QEAHE-AIRPTHPELLTLEGEIEDA----
Q8F5G0_LEPIN T---FAS-P---LE----RKIRKSAKKI---QDAHE-AIRVT-DPFLTPKEIKKFLGK--
TOP1_BORBU E---YIE-E---KD----RIYEKE-KMA---QNAHE-AIRPS-EIFI-PNETIEIESK--
H8H3H1_DEIGI A---ALP-P---SP----RQYATRNANA---QEAHE-AIRPA-GAFLAPEAT--GLNG--
B1VAJ5_PHYAS K---YLA-----------VFKQNQKNKA---QDAHE-AIKPT-DLSKTPESLMSYLDK--
TOP1_FERIS E---YLNESSEVAS----KKGSKTKGKV---QDAHE-CIRPV-DVNITPEKAKELLDK--
TOP1_THEMA E---YVG-----SK----RERRKSNAKI---QDAHE-AIRPT-NVFMTPEEAGKYLNS--
B2V7T0_SULSY D---YLP-E---KI----RVYKSK-NTQ---ADAHE-AIRITHFVNLEEQKKLIKEKGLS
TOP1_AQUAE E---YVG-----RL----RRFREK-ATA---QGAHE-CIRPTSLREEIPERE--------
D3SM80_THEAH E---YVG-----TL----RKFKEK-PTS---QGAHE-CIRPV-SLDRSPTGGV-------
G8QVT8_SPHPG D---FLS-P---TE----RHFAAKTAGA---QEAHE-AIRPSGERFRVPGET--GLSG--
TOP1_SYNE7 N---YLS-P---QP----RQFTTKSKNA---QEAHE-AIRPAGNTFRLPQET--GLSG--
TOP1_SYNY3 E---YLS-P---QP----KQYTTKSKGA---QEAHE-AIRPAGTEFRIPNQT--GLKD--
TOP1_STRCO D---YLP-P---QP----RTYAGKVKNA---QEAHE-AIRPSGDRFRTPAET--GLTG--
TOP1_MYCTU E---YVA-P---AP----RQYTRKVKNA---QEAHE-AIRPAGETFATPDAVRRELDGPN
TOP1_MYCLE E---YVS-D---SP----RQYTRKVKNA---QEAHE-AIRPAGETFATPDAVCNELDG--
I0II60_PHYMF N---YRPED---KP----RFYKSSNQDA---QEAHE-AIRPT-DVTITPSSIQNQLSE--
J9Z7K0_LEPFM G---LPA-----RP----PAYKNR-KGI---QDAHE-AIRPS-DVRRTPESLQGAIDP--
TOP1_BUCAI N---YLP-K---EP----NIYSNE-KHS---QEAHE-AIRPS-DIKIKNIDSDH-LNS--
TOP1_BUCAP D---FLP-K---KS----NIYSNQ-KYS---QEAHE-AIRPS-DVQVVNIDNCDP-----
TOP1_PSEAE K---YLP-G---KA----NVYSSK-EGA---QEAHE-AIRPS-DVNLKPTQLSG-MER--
TOP1_VIBCH A---YLP-S---QP----NVYGSK-QNA---QEAHE-AIRPS-DVTVTADDLEG-MEA--
TOP1_ECOLI K---YLP-E---SP----NQYASK-ENS---QEAHE-AIRPS-DVNVMAESLKD-MEA--
TOP1_SALTY K---YLP-D---NP----NQYASK-ENS---QEAHE-AIRPS-DVAVMAESLKD-MEA--
TOP1_HAEIN Q---YLP-E---KP----NFYSSK-ENA---QEAHE-AIRPS-DIRALPESLEG-MEK--
TOP1_PASMU S---YLP-S---KP----VFYSSK-ENA---QEAHE-AIRPS-DVNTLAEQLTG-MDK--
TOP1_CAMJE D---YLP-S---KA----NVYTTKTKGA---QEAHE-AIRPT-NLSFTPEIAAKFLDK--
TOP1_HELPY D---YLP-P---KA----KVYSSKNKNA---QEAHE-AIRPT-SIILEPNALKDYLKP--
TOP1_HELPJ D---YLP-P---KA----KVYSSKNKNA---QEAHE-AIRPT-SIILEPNALKDYLKP--
TOP1_TREPA A---LPG-----TP----NRYAAKGKS----QDAHE-AIRPT-YVAHTPERIKAHLTR--
TOP1_LACLA K---YS------KH----GSKVKNASGA---QDAHE-AIRPS-NVFNTPDAIAKYLDK--
TOP1_STAS1 D---YT------------SNRKSKGQGD---QDAHE-AIRPS-STLRTPNEMKNFLTR--
TOP1_STAAB S---YTS-----------KRKASGKQGD---QDAHE-AIRPS-STMRTPDDMKSFLTK--
TOP1_STAA8 S---YTS-----------KRKASGKQGD---QDAHE-AIRPS-STMRTPDDMKSFLTK--
TOP1_STAAU S---YTS-----------KRKASGKQGD---QDAHE-AIRPS-STMRTPDDMKSFLTK--
TOP1_STAAM S---YTS-----------KRKASGKQGD---QDAHE-AIRPS-STMRTPDDMKSFLTK--
TOP1_STAHJ D---YLS-----------NRTAKGKQGD---QDAHE-AIRPT-STLRTPYEMKAYLTR--
TOP1_STAES Q---YVS-----------QRKSSGKQGD---QDAHE-AIRPT-STMRTPDDMKAFLTR--
TOP1_BACSU E---FLG-----GK----RKPAKKNENA---QDAHE-AIRPT-SVLRKPSELKAVLGR--
TOP1_HALH5 E---YAQ-----NG----TKAVKKDKKS---QDAHE-AIRPT-SVERDPKSLKEYLSR--
A5CVH7_VESOH E---YH------NT----RRYKSKESRA---QEAHE-AIRPT-DLTRSN---IFDIEE--
Q28MI5_JANSC D---YVP-G---KP----RIYKNKAKNA---QEAHE-CVRPT-DMSKAANDLKLSED---
TOP1_XYLFT N---ALP-D---KP----NVYTTKSKNA---QEAHE-AVRPT-SALRTPTQVAPYLSN--
TOP1_XYLFA N---ALP-D---KP----NVYTTKSKNA---QEAHE-AVRPT-SALRTPTQVAPYLSN--
TOP1_RICTY K---YLP-I---NP----RIYQSKVKNA---QEAHE-AIRPT-NITYTPDNLKQKLEK--
TOP1_RICPR Q---YLP-I---KP----RIYQSKVKNA---QEAHE-AIRPT-NITYTPDSLKQKLEK--
TOP1_RICBR K---YLP-S---SP----RIYKSKVKNA---QEAHE-AIRPT-NINYIPNDLKEKLEK--
TOP1_RICFE K---YLP-N---SP----RIYKSKVKNA---QEAHE-AIRPT-NITYTPDSLKEKLEK--
TOP1_RICCN K---YLP-T---SP----RIYKSKVKNA---QEAHE-AIRPT-NITYTPDSLKEKLDK--
B7J7I8_ACIF2 P---LVE-----TP----RRWRSK-GGA---QEAHE-AIRPTRPMVRQAGENDL------
Q7WXW8_PSEAI K---CVE-----QQ----RMFKAD-QDA---QEGHP-AITPT-DWMAAAAGETA------
C6XEP4_METGS S-----------SE----KRTWKGVVAA---QEAHE-AIRPS-DMNYQPDETMTA-----
B1M9R9_METRJ A---LSP-----EV----RRWKEK-ASA---QGGHADAVRPT-HIEVEDAGADD------
TOP1P_XYLFA D---IAE-----KP----RKFKAP-AGA---QVGHP-AVTPT-HWEVEEAGETS------
C8W7T0_LANP1 TCKKLLG-----QP----KLHATRGKQE---STDHP-PIYPT--AAANPDSLQP------
E1RJ15_METP4 EVEWVSA-----NM----RPSPTRGKKS---STDHP-PIHPT------AAASKGDMDE--
C7P1M5_HALMD DAESLLE-----QD----EIVPTEGDEE---TTDHP-PIHPT-GELPPRGELDD------
TOP1_THEAC ----YVK-----EIETFDRILPSRGRIE---TTDHP-PIYPV---DSPKEQLKG------
TOP1_ARCFU EAQIVLS-----QD----KITPSRGRRE---TKDHP-PIYPT-GVAKRGELSK-------
B5IE55_ACIB4 E---ALKLQK--ER----RRYPTRGKKE---STDHP-PIVPT-----RGANLEG------
B1L3G6_KORCO EAEFVLG-----DM----REAAVEGKKD---DPAHP-TIHVV---GVPEERLEG------
TOP1_AERPE EARELLKET---GG----VLRPVQGSKD---DPAHP-AIHPT------GEKPSQRLSK--
A3DP02_STAMF LVSNLLVET---KG----VLKPVQGSKD---DPAHP-AIYPT---GVKPKDLGK------
B8D5I1_DESA1 LVESLISET---KG----VLTPVEGEKE---DPAHP-AIYPT---GVVPGRLTE------
K0IBM4_NITGG LTSMLLS-----KG----RLVPNEGRMT---DPAHP-AIYPT---GVAPQQKLSSL----
TOP1_METTH H---IERL----RG----PLKPHEGKKE---DDAHP-AIHPT---GLLPSELSK------
F6D5C7_METPW H---VAQLK---KP-----YKPNEGKKT---DEAHP-AIHPT---GVLPKELST------
TOP1_METJA W---AERIL---KE----NLKPVEGKKE---DPAHP-AIHIV---DIPKEELSE------
TOP1_PYRAB YAHLLLG-----MP----ELKPVEGKKE---DPAHP-AIYPT-GEIPGPGDLSK------
TOP1_PYRHO YAHILLG-----LP----ELKPVEGKKE---DPAHP-AIYPT-GEIPRPGDLTK------
* :
Q6F0G3_MESFL -DKNMIRLYNLIWWNTVKSLMKGPSGFYHNWTFWN-----N---G----YEFKQSWKEVL
F0V2L5_MYCS3 -SSLEFQLYRLIWSYTVASFFPSSRNEKRRYVFEN-----Q---G----NFFYASESSEV
Q9PPP9_UREPA -D--IYKLYNLVWNKTLSALMKVPTFNKQVIRFIN-----N---E----YKFYTAYKTIR
TOP1_MYCGA -D--QYSLYKLIWTRTVAHYMAAAVYELVNIRFIN-----N---N----NKFYAVNNTLK
TOP1_MYCPN -D--EFLLYRLIWIRTVASLMADCKKSHTHIRFIN-----D---G----NKFYASSKSLV
TOP1_MYCGE -D--EFLLYRLIWIRTVASLMADAKTSRTIVRFIN-----Q---K----NKFYTSSKSLL
Q3M6J7_TRIV2 -D--EFNLYVMIWKRAIASQCRPAQLRKTVVITQS-----G---Q----ILWQARGQVVE
Q4AA55_MESHJ -I--EFQIYQLIYQTTIQALMRSPERKITNLTFKT---PIK---D----HIFSYSYSEFT
B3PMD8_META1 -V--ESYIYTIIYNKTMSSLMTPPVREIYRYELVN-----G---L----YYFKMSYSKVI
TOP1P_MIMIV -Y--QIKLYKLIWQRTIASQMKPAKIKVTIIQISISKYVED---KLNPFYYFQSQIETVV
Q8F5G0_LEPIN -E--EAALYDLIWKRTISSLLPAEEFIKIEYSIFA-----A---G----ECFQLETKKTI
TOP1_BORBU -T--AKEIYKIIWDRTIISGMKDAIKENIKLTFKY-----K---N----LIFRSSFTKII
H8H3H1_DEIGI -D--ELALYTLIYTRTVASQMQDALGEKTTITLQA-----G---V----VTLGATGTRLT
B1VAJ5_PHYAS -Y--EYKLYDLIYKRSLASLMKPAIFQKNQVFFEV-----E---K----HSFLTEGLIKT
TOP1_FERIS -D--HHKLYELIWKRFIASQMSSAIYKQYSYDFES-----G---K----YVFEASIRERI
TOP1_THEMA -D--QKKLYELIWKRFLASQMKPSQYEETRFVLRT-----K---DGK--YRFKGTVLKKI
B2V7T0_SULSY ED--HFKLLKLIYERTVASQMADAIFERTSAAVDI-----K---G----YTFKASGSILK
TOP1_AQUAE -E--LRLLYDLIFRRTIASLMKEMLLEREKVTVEAITPELK---HP---VYLVAKGLKIV
D3SM80_THEAH ----EEKLFTLIMKRTLASLASPALLEKTDVVVVP---LCE---PR---MEFKGQWQRIL
G8QVT8_SPHPG -R--ELALYELIWKRTLASQMADAKKATTSVSIQA-----N---D----ALFTATGTQIV
TOP1_SYNE7 -A--EFALYDLIWKRTIASQMAEARQTMLSVLLEV-----D---N----AEFRASGKRID
TOP1_SYNY3 -R--ELALYELIWKRTVACQMADARITQLSVLLKV-----E---D----AEFRAAGKRID
TOP1_STRCO -D--QFKLYELIWKRTVASQMKDATGNSVTVKIGGAASDGR---D----VEFSASGKTIT
TOP1_MYCTU ID--DFRLYELIWQRTVASQMADARGMTLSLRITGMSGH-Q---E----VVFSATGRTLT
TOP1_MYCLE -D--EFRIYELVWRRTVASQMADARGTTLSLRIEG-----R---AGEQHVVFSASGRTLT
I0II60_PHYMF -E--QFRLYDLIWRRFVACQMVDAQFDSTSIIIAC-----E---KAE--ATFRASGSVLV
J9Z7K0_LEPFM -D--LFRLYDLIWKSFVESQMSPALYLQTTVLVEG-----D---QG---DVFRASGRVLK
TOP1_BUCAI -S--AKKLYELIWNQFLASQMKSVKYKSITVTVLA-----D---M----FKLQKSERIVM
TOP1_BUCAP -D--AKKLYKLIWNYFIASQMKSERYKSIKTTVMA-----D---V----FKLQSNTKIVL
TOP1_PSEAE -D--AERLYDLIWRQFVACQMTPAEYLSTSVSVTA-----G---D----FELRAKGRILK
TOP1_VIBCH -D--AHKLYALIWNQFVACQMTPAQYDSTTVSVKA-----A---E----YTLKAKGRILK
TOP1_ECOLI -D--AQKLYQLIWRQFVACQMTPAKYDSTTLTVGA-----G---D----FRLKARGRILR
TOP1_SALTY -D--AQKLYQLIWRQFVACQMTPAQYDSTTLTVGA-----G---E----FRLKARGRILR
TOP1_HAEIN -D--AVRLYDLIWCQFLACQMPPAQYDSSTLTVTA-----G---D----YTLKAKGRILR
TOP1_PASMU -D--AVRLYDLIWRQFVACQMPAAQYDSTTVTVRA-----G---E----YELKAKGRILR
TOP1_CAMJE -D--ELKLYTLIYNRFLACQMSPAISQTQNVFVKN-----D---R----VVFKISGRKIL
TOP1_HELPY -E--ELRLYTLIYKRFLASQMQDALFESQSVVVAC-----E---K----GEFKASGRKLL
TOP1_HELPJ -E--ELKLYTLIYKRFLASQMQDALFESQSVVVAC-----E---K----GEFKASGRKLL
TOP1_TREPA -D--QIRLYTLIWERFVASQMTDARVRSLTFEITA-----G---P----AVFSATETQVI
TOP1_LACLA -D--QLKLYTLIWNRFVASQMVAAIFDTVKVNLSQ-----N---G----VIFIANGSQVK
TOP1_STAS1 -D--QHRLYKLIWERFVASQMAPAILDTVAMDLTQ-----N---D----IKFRANGQTIK
TOP1_STAAB -D--QYRLYKLIWERFVASQMAPAILDTVSLDITQ-----G---D----IKFRANGQTIK
TOP1_STAA8 -D--QYRLYKLIWERFVASQMAPAILDTVSLDITQ-----G---D----IKFRANGQTIK
TOP1_STAAU -D--QYRLYKLIWERFVASQMAPAILDTVSLDITQ-----G---D----IKFRANGQTIK
TOP1_STAAM -D--QYRLYKLIWERFVASQMAPAILDTVSLDITQ-----G---D----IKFRANGQTIK
TOP1_STAHJ -D--QHRLYKLIWERFVASQMAPAILDTVALDVTQ-----N---N----IKFRANGQTIK
TOP1_STAES -D--QHRLYKLIWERFVASQMAPAILDTVALDVTQ-----N---D----IKFRANGQTIK
TOP1_BACSU -D--QMRLYKLIWERFVASQMAPAVLDTMSVDLTN-----N---G----LTFRANGSKVK
TOP1_HALH5 -D--QLRLYKLIWERLVASQMAPAIMDTMTVDLSN-----E---G----VLFRATGSKVK
A5CVH7_VESOH -Q--AAKLYILIYKRTLSCQMSDAQLQKTKIKINI-----E---GLD--EIFIANGEVLV
Q28MI5_JANSC -D--QRKLYDLIWKRTIASQMEAARLERTTVTIAS-----D---DRE--VELRATGQVML
TOP1_XYLFT -E--EHRLYELVWKRTVASQMIPAILNTTSVDLAA-----G---NE---HVFRATGTTVV
TOP1_XYLFA -E--EHRLYELVWKRAVASQMIPAILNTTSVDLAA-----G---NE---HVFRATGTTVV
TOP1_RICTY -D--YYKLYELIWQRTIACQMENVIMDLVIANLAS-----E---NKE--YLAKANGSIIA
TOP1_RICPR -D--YYKLYELIWHRTIACQMENVIMDLVIANLAS-----E---NKE--YLAKANGSIIA
TOP1_RICBR -D--YYKLYELIWKRTIACQMENVIMDLVNATLAS-----E---NKE--YLARANGSTIA
TOP1_RICFE -D--YYKLYELIWKRTIACQMENVIMDLVVASLAS-----E---NKE--YLAKANGSTIA
TOP1_RICCN -D--YYKLYELIWKRTIACQMENVIMDLVVANLAS-----E---NKE--YLAKANGSTIA
B7J7I8_ACIF2 ----EQALYDLIRKRALASQMPDAVYQQTSCTLDGGMFQGR---P----AVFRAVGSVLK
Q7WXW8_PSEAI -D--EQALYQLIRVRALASQIEAAVYAVRTITLLGVGPDKK---P----LRFGAKGKLLN
C6XEP4_METGS -D--EAALYRLIHSRAVASQMEPAEYTVATATLSN-----E---QG---IKFKAQSKSLC
B1M9R9_METRJ -A--QRALYRLIRLRTLVSQMADARYTVNTVRLRA-----TDRDG----FEYVARGRKMI
TOP1P_XYLFA -D--QKALYKLIRLRAIACQLADARYAVRTVRLEAAQPVGG---KN---VEFEARGRTLI
C8W7T0_LANP1 -A--AWKLYNLIARRFLATLMGPATMSGTKITLDV-----A---G----QPFVANGTVLA
E1RJ15_METP4 -T--AWKVYELVVRRFLATLSPDARWKTLKYTFDA-----G---G----EPYASTGQRLD
C7P1M5_HALMD -D--EWEIYELVVRRFFATVAEPAKWAHLRVVAEA-----A---G----HSLKANGKRLL
TOP1_THEAC -D--YGRVYDLILRHFLSTLYRDGKKTVAEAEIYV-----N---G----YTFKAAGQHTT
TOP1_ARCFU -D--EWTIYELVVRRFLATLAPKAVWDVRRVVLDS-----N---G----VKFVANGRQLV
B5IE55_ACIB4 -D--KGKIYELVVRRFMATLAPDLEYRESKVKLAV-----K---D----EIFEAKGKELV
B1L3G6_KORCO -K--YREVYEIIARRNLATLAQDALIKRIRVESNV-----D---G----FIFRASGLSVL
TOP1_AERPE -E--HMAVYELIVRRFLAAFSREAIVSKSSVLLRDF----Q---G----RVWRAEGLRVE
A3DP02_STAMF -D--EWKIYDLIVRRFLAAFASKARISHRIVYLEY-----PKDPS----MVFQASGQKIL
B8D5I1_DESA1 -K--QWAIYDLIVKRFLAVFAPPAKIVYYVVKATT-----P---SHE--YVFETKGQVIE
K0IBM4_NITGG ----EFKVYDLVVKRFLATFGDPAISRHTDVSIDV-----N---S----HTFKAQGRSPV
TOP1_METTH -D--EKKVYDLIVHRFISVFGEDAILQTMKVELEI-----G---E----EEFSFSRKRVS
F6D5C7_METPW -D--YRKLYELIVYRFISVFGENATLETMKTTLTI-----G---K----EEFNFSRKRMS
TOP1_METJA -K--EKEIYDLIARRTLAAFWDNAEREYLNVKIDI-----K---G----EKFKLSGSRTV
TOP1_PYRAB -D--EEKLYDMIVRRFLALFMEPAVRESVKVTILA-----G---P----HKFMLSGARTV
TOP1_PYRHO -D--EEKLYDMIVRRFLAVFMEPAIRESVKVTIRA-----G---P----HKFFLSGGRTV
: :: .
Q6F0G3_MESFL DLGYNKLDKFETDEDVELDENDDEISNDDEIKPP-FEFKENYVFS---------------
F0V2L5_MYCS3 FDGYKYI--LRENGLL----ESRE--KSEFDFKQLIKNNKYLSKE---------------
Q9PPP9_UREPA TLGYWILDFYKKQRDE----------LEF-QPPI-INVGDEFKKE---------------
TOP1_MYCGA FDGYKKI--YTHY-------DDKDHLRKL-DLNH-FAIDKEFEAK---------------
TOP1_MYCPN FDGYRKI--YEHFENKESN-------DLYIDLDK-IRVGDRFMAK---------------
TOP1_MYCGE FDGYQRL--YEEIKP-----NTKD--ELYIDLSK-LKIGDKFSFE---------------
Q3M6J7_TRIV2 FLGYTRY--WPNLS------------KDT-LLPT-LQQGQMVTLE---------------
Q4AA55_MESHJ FDGYYKA-----TEKP----------SLK-FKPE-FSDIESLISK---------------
B3PMD8_META1 FDGYYRV--LNFE-------------EPK-PLPK-YEIGEAIPVL---------------
TOP1P_MIMIV FPGFMKV--YVESIDDPDTDNQITKNFTG-KIPT---VGSKVTME---------------
Q8F5G0_LEPIN FPGYKIL--------------NEA--DVK-TNPS-WEKGELFILQ---------------
TOP1_BORBU FDGFLKH--TKE--------QDEH--LNI-NFDL-IKKGDTFSIV---------------
H8H3H1_DEIGI QRGFTAL--YDDD-------QKDE--DDQ-ALPA-LTTGQRAPLS---------------
B1VAJ5_PHYAS FDGYQKI--LKDNL------------QDK-IIPT-FNLNESYFPE---------------
TOP1_FERIS FDGFEKV--YTIDN------------EPSEKHKE-LKVDQEYLV----------------
TOP1_THEMA FDGYEKV--WKTE-------------RNTGEFP--FEEGESVKPV---------------
B2V7T0_SULSY FKGYKAV--YDLEEE-----EDKE--ENQ-KLPD-LKNKDVLTLE---------------
TOP1_AQUAE FDGWSRV--YPSEI------------TEE-KLPE-LYEGDLLDLV---------------
D3SM80_THEAH FDGWLRI--------E----EEEL--DLQ-EPPP-LSEGEILLPK---------------
G8QVT8_SPHPG FPGFLRA--YVEGSDD-PDAALED--KES-LLPP-LSVGEICPLV---------------
TOP1_SYNE7 FPGFFRA--YVEGSDD-PDAALED--REI-LLPA-LKVGDRPTCQ---------------
TOP1_SYNY3 FPGYFRA--YVEGSDD-PDAALEN--QEV-ILPP-LKVGDRPNCR---------------
TOP1_STRCO FHGFLKA--YVEGADD-PNAELDD--RER-RLPQ-VAEGDALTAE---------------
TOP1_MYCTU FPGFLKA--YVETVDELVGGEADD--AER-RLPH-LTPGQRLDIV---------------
TOP1_MYCLE FPGFLKA--YVETVDELAGGEADD--AER-RLPH-LTSGQLLDVI---------------
I0II60_PHYMF FDGFMRISGVPKS-------------DEV-LLPKGLEENKPIAPI---------------
J9Z7K0_LEPFM APGFLALRGLSVSQDE-DGGDGEG--EDR-LLPP-LETGESVHLE---------------
TOP1_BUCAI FQGWNKV--LIEEK------------NVFSQFPI-LQTGSQLFIN---------------
TOP1_BUCAP FSGWTKI--LKKSNN-----------VNF-KFPV-LDIGTTLILD---------------
TOP1_PSEAE FDGYTRV--LPQQ-------SKPG--EDD-VLPE-MKEGENLKLI---------------
TOP1_VIBCH FDGWTRV--QRPLGKN----------EDQ-ILPP-VKVGDSLKLV---------------
TOP1_ECOLI FDGWTKV--MPAL-------RKGD--EDR-ILPA-VNKGDALTLV---------------
TOP1_SALTY FDGWTKV--MPAL-------RKGD--EDR-TLPA-VNKGDALTLL---------------
TOP1_HAEIN FDGWTKV--LPQI-------GKNP--EDQ-ELPS-VTVSEKLALK---------------
TOP1_PASMU FDGWTKV--LPTM-------SKNA--EDQ-VLPD-VQLNEKLHLE---------------
TOP1_CAMJE FDGYYKV--YGDMD------------KDK-ILPN-FKIGQNLKVQ---------------
TOP1_HELPY FDGYYKI--LGNDD------------KDK-LLPN-LKENDPIKLE---------------
TOP1_HELPJ FDGHYKI--LGNDD------------KDK-LLPN-LKENDPIKLE---------------
TOP1_TREPA EQGFYRV--L--KMLS----PKDL--SKA-VLPP-TKEGEVVALH---------------
TOP1_LACLA FDGYLRI--Y----------NDSD--KSN-MLPE-MEENETVKKA---------------
TOP1_STAS1 FKGFMTL--YVETKDD----SEDG--KDN-KLPN-IGEGEMVTAT---------------
TOP1_STAAB FKGFMTL--YVETKDD----IDSE--KEN-KLPK-LEQGDKVTAT---------------
TOP1_STAA8 FKGFMTL--YVETKDD----SDSE--KEN-KLPK-LEQGDKVTAT---------------
TOP1_STAAU FKGFMTL--YVETKDD----SDSE--KEN-KLPK-LEQGDKVTAT---------------
TOP1_STAAM FKGFMTL--YVETKDD----SDSE--KEN-KLPK-LEQGDKVTAT---------------
TOP1_STAHJ FKGFMTL--YVEAKDD----KDNE--KEN-KLPN-LSKGDEVTAT---------------
TOP1_STAES FKGFMTL--YVEAKDD----KEND--KEN-KLPQ-LDKGDKVTAT---------------
TOP1_BACSU FSGFMKV--YVEGKDD----QMEE--KDR-MLPD-LQEGDTVLSK---------------
TOP1_HALH5 FPGFMKV--YIEGNDE----GKKE--EDR-LLPN-LQEGQTVTKE---------------
A5CVH7_VESOH FPGFLRI--YDYLLS-----------EDK-LLPR-LNKGNALNLV---------------
Q28MI5_JANSC FDGFLKV--YEEGRDD---AGDDE--DSK-RLPQ-VSAGDPLKPSADAMADDYAKYSGDD
TOP1_XYLFT VQGFLAV--YEEGKDN-KNAEDDD--EGR-KLPV-MKTGENVPLE---------------
TOP1_XYLFA VQGFLAV--YEEGKDN-KNAEDDD--EGR-KLPV-MKTGENVPLE---------------
TOP1_RICTY FDGFYKV--YRESLDD----EDEE--DNK-MLPP-LKAQEHIKTK---------------
TOP1_RICPR FDGFYKV--YRESLDD----EDEE--DNK-MLPP-LKEQEHIKTK---------------
TOP1_RICBR FDGFYKV--YRESIDD----EAEE--ENK-MLPP-LKEQEHLKTK---------------
TOP1_RICFE FDGFYKV--YRESVDD----EAEE--ENK-MLPP-LKEQEPLKTK---------------
TOP1_RICCN FDGFYKV--YRESMDD----EAEE--ENK-MLPP-LKEQEPLKTK---------------
B7J7I8_ACIF2 DPGWMAL--YRETAEDEEGTENP---AAN-PVPR-LAVGDAVRAA---------------
Q7WXW8_PSEAI VPGWRKL--LQGDDAEEQKNETPS--NPI-PIPA-LEPRQILKVY---------------
C6XEP4_METGS KPGWRVL--AVQDEEH----DDNP--SLS-HIPD-LSVGQILHSS---------------
B1M9R9_METRJ DAGWRAL--LERDPDEEENSDDDA--AKDGQVPR-LAVGGDLRAI---------------
TOP1P_XYLFA YQGWLKL--IAGDQTEEEDGNEKE--SSN-PIPV-CAPGECLDVA---------------
C8W7T0_LANP1 EPGFREI--YPFGLK-----------KDD-QIPD-VGEGEIVSIK---------------
E1RJ15_METP4 YEGYRIV--YTYSQA-----------KEQ-ALPV-LAAGEKLPIL---------------
C7P1M5_HALMD EPGYHAV--YPYSSA-----------SEN-VVPA-VSEGDALTMS---------------
TOP1_THEAC DRGWTEI--YGYDP------------KDV-YLPE-LTEGEDLKAI---------------
TOP1_ARCFU EAGWRDI--YIYSKA-----------EET-ELPL-LKKGDVLRIL---------------
B5IE55_ACIB4 NEGWLYY--YPYARF-----------EEE-KIPI-LRIGDEVKVK---------------
B1L3G6_KORCO REGWLRV--YPYA-------------RME-EFPE-VEDSEELRVV---------------
TOP1_AERPE DLGWLKY--YHYSTP-----------GEK-PMPP-LDRGDKARVV---------------
A3DP02_STAMF DLGWLRY--YPFSKP-----------EER-FLPK-FQYGEKVKIV---------------
B8D5I1_DESA1 EYGWLKY--YNFHNY-----------HAG-KIPV-LKEGELLNIV---------------
K0IBM4_NITGG YEGWMVF--YKPHVRL----------EQH-ELPE-LRKGDLVKNL---------------
TOP1_METTH KAGWMES--YPYTKM-----------EDE-EFPE-ISGGDSLAVR---------------
F6D5C7_METPW KMGWMGH--YPFRKI-----------EED-YFPT-MNKGETLNVK---------------
TOP1_METJA KEGWHEI--Y-YFPKF----------DEI-ELPP-LKKNDIIKVE---------------
TOP1_PYRAB KQGWLSV--YGKYIKF----------DEV-TLPE-FFIGERVRVL---------------
TOP1_PYRHO KKGWLSV--YGKYVKF----------EEV-TLPE-FFIGERIKVI---------------
*
Q6F0G3_MESFL ------------------INKNAIVTEEAK----------TSPPRMFNQASLVRELKDLG
F0V2L5_MYCS3 ----------------------DIIMEER-----------NSPPSKYSEATLIKALENKG
Q9PPP9_UREPA ----------------------KIDLIQKE----------TTPPPYYTEASLIAALKNAG
TOP1_MYCGA ----------------------DVLLNEHQ----------TKPPARFTQATLIEALETEG
TOP1_MYCPN ----------------------DIKITARQ----------THPAARYTQASLIEALEKSN
TOP1_MYCGE ----------------------KISVNEHK----------TNPPPRYTQASLIEELEKSN
Q3M6J7_TRIV2 ----------------------NAGHEKKQ----------TQPPPRYSEPKLVQLMERKG
Q4AA55_MESHJ ----------------------KFQVDKNFDNSIKSSLHQTKPPAHFRDGTLIEKLDDEK
B3PMD8_META1 ----------------------EFTRFDKE----------TQPPARYNEGSLIKMLDDIK
TOP1P_MIMIV ----------------------EIIARQEY----------MRPPPRYSEASLVKKLEELG
Q8F5G0_LEPIN ----------------------KVECEKKQ----------TEPPSRYSEGTLVAKLEKQG
TOP1_BORBU ----------------------KMKTSEHE----------TKAPFRYTEASLVQKMEKEG
H8H3H1_DEIGI ----------------------KVKAEEKK----------SSAPARFSEGSFVQLMEKAG
B1VAJ5_PHYAS ----------------------KIETFQKF----------TTPQARFSEATLIKTLEKLN
TOP1_FERIS ----------------------EPKSAEAQ----------TTPPDRYTEASLVKTLEMEG
TOP1_THEMA ----------------------VVKIEEQE----------TKPKPRYTEGSLVKEMERLG
B2V7T0_SULSY ----------------------KINLEEKF----------TKPPARYTEGGLVKKLEELG
TOP1_AQUAE ----------------------KTTLEERK----------TQPPPRYTEGTLIKTLEKLG
D3SM80_THEAH ----------------------KVTLEERR----------TEPPPRYTEATLVKTLEKLG
G8QVT8_SPHPG ----------------------KLSEVEHQ----------TKPPARYTEASLVQELEKRG
TOP1_SYNE7 ----------------------ELAAIGHE----------TQPPARYTEASLVKMLENEG
TOP1_SYNY3 ----------------------EIDTVGHE----------TQPPARYTEASLVKTLESEG
TOP1_STRCO ----------------------EITVDGHA----------TKPPARYTEASLVKELEERE
TOP1_MYCTU ----------------------ELTPDGHA----------TNPPARYTEASLVKALEELG
TOP1_MYCLE ----------------------DLTPDGHA----------TNPPARYTEASLVKALEELG
I0II60_PHYMF ----------------------DLDPRQQF----------TSPPARYTEASLQKELEKEG
J9Z7K0_LEPFM ----------------------EVTPDQHF----------TEPPPRYSEASLIRELEEKG
TOP1_BUCAI ----------------------KVTPSQKF----------TKPPPRFSEASLVRELEKKG
TOP1_BUCAP ----------------------KILPHQIF----------TKPPPRFSESSLVRELEKKG
TOP1_PSEAE ----------------------KLDPSQHF----------TKPPARYSEASLVKELEKRG
TOP1_VIBCH ----------------------SLDPKQHF----------TKPPARYTEAALVKELEKRG
TOP1_ECOLI ----------------------ELTPAQHF----------TKPPARFSEASLVKELEKRG
TOP1_SALTY ----------------------ELTPAQHF----------TKPPARFSEASLVKELEKRG
TOP1_HAEIN ----------------------EVQPTQHF----------TKPPARFTEAALVKELEKRG
TOP1_PASMU ----------------------HVLPEQLF----------TKPPARFSEAALVKELEKRG
TOP1_CAMJE ----------------------NLEMNSHF----------TEPPSRYSEAGLVKKLESLG
TOP1_HELPY ----------------------KLESNAHV----------TEPPARYSEASLIKVLESLG
TOP1_HELPJ ----------------------KLESNAHV----------TEPPARYSEASLIKVLESLG
TOP1_TREPA ----------------------NVQSVQHF----------TQGPVRYTDASIVKMLEEKG
TOP1_LACLA ----------------------NVKPEQHF----------TQPPARYSEATLIKTLEENG
TOP1_STAS1 ----------------------NIEPSQHF----------TQPPPRYTEARLVKTMEELK
TOP1_STAAB ----------------------QIEPAQHY----------TQPPPRYTEARLVKTLEELK
TOP1_STAA8 ----------------------QIEPAQHY----------TQPPPRYTEARLVKTLEELK
TOP1_STAAU ----------------------QIEPAQHY----------TQPPPRYTEARLVKTLEELK
TOP1_STAAM ----------------------QIEPAQHY----------TQPPPRYTEARLVKTLEELK
TOP1_STAHJ ----------------------QIEPAQHF----------TQPPPRYTEARLVKTLEELK
TOP1_STAES ----------------------KIEPAQHF----------TQPPPRYTEARLVKTLEELK
TOP1_BACSU ----------------------DIEPEQHF----------TQPPPRYTEARLVKTLEERG
TOP1_HALH5 ----------------------EIEPSQHF----------TQPPPRYTEARLVKTMEELG
A5CVH7_VESOH ----------------------NFKARESF----------SRAKPRYTEASLVKKIEEMG
Q28MI5_JANSC VVEDDGNGDVRRSKSAILSREGAVLGQQHH----------TAPPPRYTEATLVKRMEELG
TOP1_XYLFT ----------------------RILTEQHF----------TQPPPRYTEAALVKALEEYG
TOP1_XYLFA ----------------------RILTEQHF----------TQPPPRYTEAALVKALEEYG
TOP1_RICTY ----------------------EVIPNKHF----------TEPPPRYSEASLVKKLEELG
TOP1_RICPR ----------------------EVIPNKHF----------TEPPPRYSEASLVKKLEELG
TOP1_RICBR ----------------------EIIPNQHF----------TEPPPRYSEASLVKKLEELG
TOP1_RICFE ----------------------EIIPNQHF----------TEPPPRYSEASLVKKLEELG
TOP1_RICCN ----------------------AVIPNQHF----------TEPPPRYSEASLVKKLEELG
B7J7I8_ACIF2 ----------------------RGECLSKT----------TKAPPRYTESTLIKALEDHG
Q7WXW8_PSEAI ----------------------SGEVLEKK----------TTPPKRFTDASLVGEMKRRG
C6XEP4_METGS ----------------------NVTVCEHS----------TRPPKRYTKASLTNALERLG
B1M9R9_METRJ ----------------------DGKVLDKK----------TEPPRRFTEATLLQKLEDEG
TOP1P_XYLFA ----------------------RGKLLEKK----------TKPPSHYTQATLVKKLESEG
C8W7T0_LANP1 ----------------------SLSLDAKQ----------TEPPARYSQGKLIQEMEKRG
E1RJ15_METP4 ----------------------DIRLEEKE----------TLPPPRYSQSKLIQVMEELG
C7P1M5_HALMD ----------------------DVSLDAKQ----------TQPPRRYGQSRLIKKMEDFG
TOP1_THEAC ----------------------DWNIQREE----------TKPPPRYDMSSLLKKMEELN
TOP1_ARCFU ----------------------KKRLEEKE----------TKPPGRYSASSLIKMMEKLN
B5IE55_ACIB4 ----------------------KIEIERKE----------TRPPARYTQSSLIREMEKLN
B1L3G6_KORCO ----------------------EVKIEEKE----------TQPPKRYSHISLIKEMERLG
TOP1_AERPE ----------------------RVDVRVEW----------SQTPVRLDKASLLRWMESVN
A3DP02_STAMF ----------------------KASIRKTY----------TKPPEKINKIKILRWMENVG
B8D5I1_DESA1 ----------------------KATASESY----------TKPPKRLTKTDLLRWMESVE
K0IBM4_NITGG ----------------------GIDMEEKF----------TQPPYRYNQASLLAKMEQEQ
TOP1_METTH ----------------------SVSADERE----------TKPPARYNEASLIRELERRG
F6D5C7_METPW ----------------------EVRAEDKE----------TKPPARYNQASLIRELEKRG
TOP1_METJA ----------------------KITITRKE----------TQPPKRYTVASIIKELEKRG
TOP1_PYRAB ----------------------QVRREKKK----------TKPPARYSPAAVIKKMEDLG
TOP1_PYRHO ----------------------QVKREKKK----------TKPPARYSPAAVIKKMEDLG
. :.
Q6F0G3_MESFL IGRPSTYTPTLSKLKEREYAIP-------------------------------------H
F0V2L5_MYCS3 IGRPSTYPLISEIVRTRNYANF-------------------------------------K
Q9PPP9_UREPA VGRPSTYATMATIGTTRGYINK-------------------------------------D
TOP1_MYCGA IGRPSTYSTILDIVLKRNYAEL-------------------------------------V
TOP1_MYCPN IGRPSTYNTMASVNLDRGYASL-------------------------------------N
TOP1_MYCGE IGRPSTYNTMASVNLERGYANL-------------------------------------V
Q3M6J7_TRIV2 IGRPSTYSPTIATLKKRGYVEL-------------------------------------T
Q4AA55_MESHJ VGRPSTFAISVKKLKDHLYVDS-------------------------------------E
B3PMD8_META1 VGRPSTFASTINIIKKRLFVET-------------------------------------I
TOP1P_MIMIV IGRPSTYVNTIKTIINREYVKITDVPGIKKDITIYSIKSENKKHIMEVYEDTDTILLGKE
Q8F5G0_LEPIN IGRPSTYATVSETLLKRKYVYE-------------------------------------E
TOP1_BORBU IGRPSTYSTIISTLLEREYAFK-------------------------------------L
H8H3H1_DEIGI IGRPSTYASTLKTLLGRNYVAI-------------------------------------R
B1VAJ5_PHYAS IGRPSTYSQIIFTLKKRFYVDM-------------------------------------I
TOP1_FERIS IGRPSTYATIIQTLLDRGYVVK-------------------------------------K
TOP1_THEMA IGRPSTYASTIKLLLNRGYIKK-------------------------------------I
B2V7T0_SULSY IGRPSTYATIIKTIKERGYVVK-------------------------------------E
TOP1_AQUAE IGRPSTYATIVKTLKERGYVEV-------------------------------------K
D3SM80_THEAH IGRPSTYAQIVKTLKDRGYVTE-------------------------------------E
G8QVT8_SPHPG IGRPSTYATIIKTLLDRKYVVK-------------------------------------D
TOP1_SYNE7 IGRPSTYASIIGTIVDRGYAQL-------------------------------------V
TOP1_SYNY3 VGRPSTYASIIGTIIDRGYVQM-------------------------------------R
TOP1_STRCO IGRPSTYASIIGTILDRGYVFK-------------------------------------K
TOP1_MYCTU IGRPSTYSSIIKTIQDRGYVHK-------------------------------------K
TOP1_MYCLE IGRPSTYSSIIKTVQDRGYVQK-------------------------------------K
I0II60_PHYMF IGRPSTYAAIIGTIQDRKYVET----------------------------------VNAR
J9Z7K0_LEPFM IGRPSTYATILSTIQDREYVEK-------------------------------------K
TOP1_BUCAI IGRPSTYSAITSKIQDRGYVKI-------------------------------------K
TOP1_BUCAP IGRPSTYATIITKIKEKGYLKI-------------------------------------K
TOP1_PSEAE IGRPSTYAAIISTIQERGYVTT-------------------------------------H
TOP1_VIBCH IGRPSTYASIISTIQDRGYVKV-------------------------------------D
TOP1_ECOLI IGRPSTYASIISTIQDRGYVRV-------------------------------------E
TOP1_SALTY IGRPSTYASIISTIQDRGYVRV-------------------------------------E
TOP1_HAEIN IGRPSTYAAIISTIQERGYVRT-------------------------------------E
TOP1_PASMU IGRPSTYAAIISTIQERGYVRV-------------------------------------E
TOP1_CAMJE IGRPSTYAPTISILTSRDYVTI-------------------------------------D
TOP1_HELPY IGRPSTYAPTISLLQNRDYIKV-------------------------------------E
TOP1_HELPJ IGRPSTYAPTISLLQNRDYIKV-------------------------------------E
TOP1_TREPA IGRPSTYAPTISVLLDRYYVTR-------------------------------------I
TOP1_LACLA VGRPSTYAPTLETIQKRYYVRL-------------------------------------S
TOP1_STAS1 IGRPSTYAPTIDTIQKRNYVKN-------------------------------------E
TOP1_STAAB IGRPSTYAPTIDTIQKRNYVKL-------------------------------------E
TOP1_STAA8 IGRPSTYAPTIDTIQKRNYVKL-------------------------------------E
TOP1_STAAU IGRPSTYAPTIDTIQKRNYVKL-------------------------------------E
TOP1_STAAM IGRPSTYAPTIDTIQKRNYVKL-------------------------------------E
TOP1_STAHJ IGRPSTYAPTIDTIQKRNYVKL-------------------------------------E
TOP1_STAES IGRPSTYAPTIDTIQKRNYVKL-------------------------------------E
TOP1_BACSU IGRPSTYAPTLDTIQRRGYVAL-------------------------------------D
TOP1_HALH5 IGRPSTYAPTLDTIQKRGYVAL-------------------------------------D
A5CVH7_VESOH IGRPSTYSTMVSTVQDRNYVTKKNGRGVEREYQLIEIKDN------QVIQSQPSEVISGE
Q28MI5_JANSC IGRPSTYASIMDTIQNRGYVIK-------------------------------------D
TOP1_XYLFT IGRPSTYASIIQTLLFRKYVDM-------------------------------------E
TOP1_XYLFA IGRPSTYASIIQTLLFRKYVDM-------------------------------------E
TOP1_RICTY IGRPSTYASILSVLQDRKYVTL-------------------------------------E
TOP1_RICPR IGRPSTYASILSVLQDRKYVAL-------------------------------------E
TOP1_RICBR IGRPSTYATILSVLQDRKYVTL-------------------------------------E
TOP1_RICFE IGRPSTYASILSVLQDRKYVSL-------------------------------------E
TOP1_RICCN IGRPSTYASILSVLQDRKYVAL-------------------------------------E
B7J7I8_ACIF2 VGRPSTYASILKNLFAREYIRR-------------------------------------K
Q7WXW8_PSEAI IGRPSSYASIVKNIIDKGQVQM-------------------------------------K
C6XEP4_METGS IGRPATYASMVDGLTDRSYVQV-------------------------------------V
B1M9R9_METRJ VGRPATFAAIMTNVLGRSYVEL-------------------------------------D
TOP1P_XYLFA IGRPATYAAIMDNIVSRGYVKT-------------------------------------E
C8W7T0_LANP1 LGTKSTRASIIDTLYQRKYLKN--------------------------------------
E1RJ15_METP4 LGTKSTRHDVIGKLFSRRYVEG--------------------------------------
C7P1M5_HALMD LGTKSTRHNTIEKLYDRGYIEG--------------------------------------
TOP1_THEAC LGTKSTRHDIIGKLIERGFIEG--------------------------------------
TOP1_ARCFU LGTKSTRHEIIQKLVSRRYIHG--------------------------------------
B5IE55_ACIB4 LGTKSTRAEIIQKLFERGYVRG--------------------------------------
B1L3G6_KORCO LGTKNTRVQIIDILKSRGYLEE--------------------------------------
TOP1_AERPE IGTEGTRARIIETLYKRGYLEG-------------------------------------S
A3DP02_STAMF IGTEATRARIIEILFSRYYLRS-------------------------------------V
B8D5I1_DESA1 IGTEATRAQIIEKLFERKYLYQ-------------------------------------H
K0IBM4_NITGG IGTKATRADIIATLFKRNYIAS-------------------------------------S
TOP1_METTH LGTKSTRADIIAKLYDRKYIEG--------------------------------------
F6D5C7_METPW LGTKSTRANIIDILFSRKYVEG--------------------------------------
TOP1_METJA LGTKATRAEIIDKLIKRGYVID-------------------------------------D
TOP1_PYRAB IGTKATRAQILETLYQRGYIEG-------------------------------------K
TOP1_PYRHO LGTKATRAQILETLYQRGYIEG-------------------------------------K
:* : .
Q6F0G3_MESFL RGK--PFEVTEKGYQAEEFLYNKYEDFFNVNYTAKMEENLDEIAEGKFDYKDWIKTIYED
F0V2L5_MYCS3 N-K--KFEITELGYKVSKDLDQNFSNFISYDYTRTMEEELDNISKLKTDWKKFLEGVFIA
Q9PPP9_UREPA K-S--KLIPTELGIKVIQELKEAFPKVISIKFTSEMEERLDVIANGKLFWKDLVSTFIPI
TOP1_MYCGA NGR--YYKTTDLGQKLAFELDKNFPTIINKEFTKNMETTLDEIAQGTVNDVSYLQAFWND
TOP1_MYCPN K-H--AFHVTQLGEQVNEELSKHFGKIINKEFTKNMEKSLDEIAENKKNYQEFLRDFWSN
TOP1_MYCGE N-R--FFYITELGEKVNNELSKHFGNVINKEFTKKMEKSLDEIAENKVNYQEFLKQFWTN
Q3M6J7_TRIV2 K-D--NLHPTNLGLEVDTFLQKALPDLLEAEFTAKMENALDAIAEGKQPWQIYLTTWNQN
Q4AA55_MESHJ S-K--SLVLSDFGKIVYENLKIISPEIIDAKFTAQVEEELDLIAQGKQDYKKYLDSMWSK
B3PMD8_META1 N-G--ALHPTVFGEVVLKKLIEGFPNTITEEYTAQVEEELDEVSEGKADYKILLEDFWNR
TOP1P_MIMIV N-K--KIVPTNLGITVNDFLMKYFPEFLDYKFTANMETDLDYVSTGTKNWVDIVQDFYDK
Q8F5G0_LEPIN K-K--FFYPFSLGEKVNFFLQSSFGELFREKFTAELESDLDRIEKKEIDSNSILNRLWLD
TOP1_BORBU N-N--TLMPTIKGAAVINLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYLSKFYNG
H8H3H1_DEIGI A-R--KLHVTPLGLCVALYLLQQLPQLVDARFTAQMEQDLDAIANGELKRLDYLDRVWRD
B1VAJ5_PHYAS E-K--RFQPTEQGILTIQNLELFFKQFLDYQYTAQMESDLDKIASGLVDNKQLMQTFYTN
TOP1_FERIS R-K--TLIPTILGFVVNHYLEQRFPDIVDKGFTAEMEKELDEVENGKKDWKEVVKSFLKE
TOP1_THEMA R-G--YLYPTIVGSVVMDYLEKKYSDVVSVSFTAEMEKDLDEVEQGKKTDKIVLREFYES
B2V7T0_SULSY N-G--SLRPTENAFHLIEYLNTRYNWVIDYSFTKKMEDFLDKVEENKKDWKEFVKQLHEK
TOP1_AQUAE K-K--ALVPTEIAFQVVEFLMERFPTLMDYKFTAQMEEKLDLVEEGKLNWKSVVYEFMEK
D3SM80_THEAH K-G--VLKPTPLGEQVLDFLEKYYPRLVDYKFTAYMEEELDSVEEGKD-WKTAVRYLFRA
G8QVT8_SPHPG G-P--ALAPTFIGFGVCQYLEDYFAQFVDYDFTSTMESGLDQIASGQLDKESFLEKFYLG
TOP1_SYNE7 S-N--TLTPTFTAFAVTALLEQHFPDLVDTSFSARMEQSLDDISNGEVDWLPYLSQFYRG
TOP1_SYNY3 S-K--ALTPTFTAFAVVSLLESHFPDLVDTGFTSRMEQKLDEIAIGKTQWLPYLQGFFLG
TOP1_STRCO G-T--ALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQSVPWLRRFYFG
TOP1_MYCTU G-S--ALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFG
TOP1_MYCLE G-S--ALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIANGNEQRTNWLNNFYFG
I0II60_PHYMF D-K--RLMATDLGKVVTDKLIEAFPEILDVGYTRDLEAQLDDIENDGRDWRKTLGDFYKP
J9Z7K0_LEPFM D-N--RFHPTDLGKAVNRLLVESFPDLMSVRFTARMEEELDQVEEGERGYRDVVGDFYTP
TOP1_BUCAI K-N--KFYAEKMGEILTIRLKKSFSNLIDYNFTAHMEKKLDQVAENKVTWRYLLDDFFKK
TOP1_BUCAP K-N--KFYAAKIGEILITRLKKNFSDLVDYDFTARMEKNLDQVSDKLINWKHLLNSFFDN
TOP1_PSEAE N-R--RFYAEKMGDIVTDRLNESFANLMDYGFTAGMEEHLDDVAQGERDWKHLLDEFYGD
TOP1_VIBCH Q-R--RFFAEKMGEIVTDRLDENFDDLMNYDFTARMEEKLDQIAEGEVNWTAVLDEFFAD
TOP1_ECOLI N-R--RFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSD
TOP1_SALTY N-R--RFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSD
TOP1_HAEIN N-R--RFYAEKMGEIVTDRLNESFGELMNYDFTANMEDTLDKIASGSVNWKTELNQFFKD
TOP1_PASMU N-R--RFYAEKMGEIVTDRLNQSFTALMNYDFTANMENILDQIANGEKNWKTELNQFFKD
TOP1_CAMJE K-K--QLIPSDVAFNVTEVLEKNFSDIVDSKFTSNLENTLDEIAEDKADWQETLKEFYYP
TOP1_HELPY K-K--QISALESAFKVIEILEKHFEEIVDSKFSASLEEELDNIAQNKADYQQVLKDFYYP
TOP1_HELPJ K-K--QISALESAFKVIEILEKHFEEIVDSKFSASLEEELDNIAQNKADYQQVLKDFYYP
TOP1_TREPA Q-K--QLMPTPLGKVISDLLTTYFHDVVDVSFTARMESKLDEVEEDKIKWNCVIADFYPA
TOP1_LACLA A-K--RFEPTELGEIVNKLIVEFFPNIVNTEFTAEMEKDLDEVEEGKRQWIEVVDQFYKP
TOP1_STAS1 S-K--RFVPTELGEIVHEQVKDYFPEIIDVDFTVNMETLLDKVADGEIGWKKVISDFYSS
TOP1_STAAB S-K--RFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSS
TOP1_STAA8 S-K--RFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSS
TOP1_STAAU S-K--RFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSS
TOP1_STAAM S-K--RFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSS
TOP1_STAHJ S-K--RFVPTELGEIVYEQVKDYFPEIIDVEFTVNMETLLDKIAEGDIGWRKVIDNFYGS
TOP1_STAES S-K--RFIPTELGEIVYEQVKEYFPEIIDVEFTVNMETLLDKIAEGDMNWRKVIGDFYNS
TOP1_BACSU N-K--RFVPTELGQIVLDLIMEFFPEIINVEFTAKMERDLDHVEEGNTEWVKIIDNFYTD
TOP1_HALH5 E-R--RFVPTELGEIVLELMTEFFPEILDVEFTAKMEDDLDSIEEGKQQWIKIIDDFYKG
A5CVH7_VESOH K-N--KLFPTNIAYLLTDFLVKYFNNIIDYKFTAKLESDFDTIATQNISWQGVVKNFYIP
Q28MI5_JANSC K-G--RLIPEDKGRLVTVFLSNYFNRYVQYDFTADLEQQLDEVSAGDRHYKDVLDRFWRD
TOP1_XYLFT G-R--SFRPTDIGRAVSKFLSSHFTQYVDYDFTAHLEDELDAISRGEEEWIPLMKKFWVP
TOP1_XYLFA G-R--SFRPTDIGRAVSKFLASHFTRYVDYDFTAHLEDELDAISRGEEEWIPLMKKFWVP
TOP1_RICTY K-K--RFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKTSLNNFWSG
TOP1_RICPR K-K--RFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKTALNNFWRG
TOP1_RICBR K-K--RFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKSALGNFWNG
TOP1_RICFE K-K--RFMPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKAALNNFWSG
TOP1_RICCN K-K--RFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGKLEWKAALNNFWSG
B7J7I8_ACIF2 G-KSPALYATELGEKIVEALSVF--DFSNVDYTREVEADLDRITEGQMRPRDLLAKSFAD
Q7WXW8_PSEAI G-R--SLIPGELGEATIALLEHNFS-FLSLDFTRNLEVALDRIANSEDTYMNVVQQFYQL
C6XEP4_METGS E-R--FLTPEPVGFAIYDALKGAFS-FIETEYTRGMESDLDLIVKGDKTYRSVVSSKYSD
B1M9R9_METRJ KKR--CLLPTEIGELVVDNLLRGQFGFMELGFTRELEVQLDAIAEGKASYRDVVEPAYRQ
TOP1P_XYLFA K-K--YLFPTETGELIVDSLVGKF-EFLDLGFTREIEESLDRIAQGESGYKAVIAKVHDQ
C8W7T0_LANP1 --D--PVEPSQLGMAIVDALSQFAPHITSPDMTAELESDMTSVAEGKDTRDGVVTHSRSL
E1RJ15_METP4 --N--PLKPTLVGRAVTESLEDHAGLITKPDMTRTLEEHMEEIKKSILSKDSVVQESREM
C7P1M5_HALMD --D--PPRPTTLAEAVVEAAEEFADRIVSEEMTAQMEADMSAIASGEATLDEVTAESREM
TOP1_THEAC --N--PVKPTPLGMAFIDAVRSVNSHIADPEMTAKLEEDMDRIEKNEMSKNDVVEESKKM
TOP1_ARCFU --N--PFRPSETAFSVINVLKETAETITLPDMTAKLENEMDLIAEGKKREPEVVDESREM
B5IE55_ACIB4 --N--PIRPTQLGKALIESLEGNNVDVIKPDMTARLEMDMDEIEKGSKAPEFVVKESREM
B1L3G6_KORCO --G--SFKPTRLGEAIVEVLESFVPALTNPELTAKLERGMNEIELGKLDPSNFLKESLDE
TOP1_AERPE R----KSEVTPLGEAVAVIIQTLFPELSKPDLTRRFESMIEDIRSGRRTRQEVIDMSKKT
A3DP02_STAMF G-G--RVEATDLGLGIIEVLMEYFPEITSVSLTRHFEEEMEKIRLGVKRREEVVKDAKNT
B8D5I1_DESA1 Q-KSSGIDVSEIGFGVVEILEKFFPDLLSVELTRKFEKEMDSIRSGVKRRSEVLEEARRV
K0IBM4_NITGG VRG--GIEVTDLGFAVIDSMRTFVPAIISTSLTRSMEEQLEKVEQGSAESVLVIEQAVDK
TOP1_METTH --K--KIRVSPLGENIIDTLTRYCEKIISEELTRQFERELEDIMRGKISKDRVIDEAITE
F6D5C7_METPW --K--KITVNKLGEQLIDTLRKYSKKITSEELTREFETKLEGIMEGKDKKDKIIDEARVE
TOP1_METJA G----SLKVTDLGISVIETLKRFCPEIIDEKMTRDLEEKLEKIQFRKIKKDDVLDEAEKR
TOP1_PYRAB K----SIKVTPLGMKVIETLEKYVPEIISVELTREFERKMDLIMQGKLTKEEVIEEAKVK
TOP1_PYRHO K----SIKVTPLGMKVIETLEKYVPEIISVELTREFEKKMELIMEGRLTKEEVIEEAKER
. : .* : :
Q6F0G3_MESFL -LNASVKAQIQ------------------------------------------------E
F0V2L5_MYCS3 -WNDSLKGAEKA------------------------------------------------
Q9PPP9_UREPA -FEEEVKQAYT---------------------KIEKVP----------------------
TOP1_MYCGA -FSEVLNEAKT---------------------NIVKKV----------------------
TOP1_MYCPN -FKEEVKLAE-------------------G--SIQRVKK--------------------E
TOP1_MYCGE -FKSDVKLAEN---------------------SIQKVKKE--------------------
Q3M6J7_TRIV2 YFAPALAKAKT-------IAVD-------S--GNPTKTF-----PPR------------Q
Q4AA55_MESHJ -IENTIEKAVE---------------------VEKVIME---------------------
B3PMD8_META1 -FQRSYDDASK---------------------TIEISIM--------------------P
TOP1P_MIMIV -LKPIVDELSK-----------------------QKGLS---------------------
Q8F5G0_LEPIN -LQTQIQNSKF--------------ILFQKEWATVLQKK---------------------
TOP1_BORBU --KKGLKDTVM---------------------QLEPKID--------------------S
H8H3H1_DEIGI ALKPAIAGAQ--------------------------------------------------
B1VAJ5_PHYAS -FLQLYQIADQ---------------------KLEKIK----------------------
TOP1_FERIS -FNKDLERAKN---------------------EFFAI-----------------------
TOP1_THEMA -FSSVFDRNDR-------------------------IVV---------------------
B2V7T0_SULSY SGSKQNVKISK---------------------KM--------------------------
TOP1_AQUAE IFGKELEMVR--------------------------------------------------
D3SM80_THEAH ------------------------------------------------------------
G8QVT8_SPHPG --AEGLENQNT------L--------------QLAQDNK--------------------V
TOP1_SYNE7 --DRGLEEQV----------------------KLRESE----------------------
TOP1_SYNY3 --ESGLENQV----------------------KVRQDQ----------------------
TOP1_STRCO -EGDGTGGGGA---------ADAGNGDGDHLGGLKELVT--------------------D
TOP1_MYCTU -GDHGVPDSVA------------------RSGGLKKLVGINLEGIDAR------------
TOP1_MYCLE -GNHGVSDSIA------------------RSGGLKKLVGVNIEGIDAR------------
I0II60_PHYMF -FKVQLDDAM-------------------A--NMTHAKA--------------------A
J9Z7K0_LEPFM -FHHEVEKAKK------------------G--GMANLKK--------------------L
TOP1_BUCAI -FSEQLEQAKK-------SPEE-------G--GMELN----------------------N
TOP1_BUCAP -FSQQLEQAKK-------PPEE-------G--GMELN----------------------T
TOP1_PSEAE -FKKKLEVAEV-------SEK-----------GMRAN----------------------Q
TOP1_VIBCH -FSRDLETAEQ-------DESL-------G--GMKPN----------------------H
TOP1_ECOLI -FTQQLDKAEK-------DPEE-------G--GMRPN----------------------Q
TOP1_SALTY -FTQQLDKAEK-------DPEE-------G--GMRPN----------------------Q
TOP1_HAEIN -FSSQLSKAEL-------DELE-------G--GMRPN----------------------S
TOP1_PASMU -FSQQLSQAEL-------DELE-------G--GMKPN----------------------S
TOP1_CAMJE -FMRKIEEGKT---------------------KIASQKT---------------------
TOP1_HELPY -FMDKIEAGKK---------------------NIISQKV---------------------
TOP1_HELPJ -FMDKIEAGKK------------------N--IISQK----------------------V
TOP1_TREPA -FSEKVSTVMK---------------------DLNSMRGVF-------------------
TOP1_LACLA -FAKELENAEE---------------------GMEKIQI--------------------K
TOP1_STAS1 -FKQDVERAEE---------------------EMEKIEI--------------------K
TOP1_STAAB -FKQDVERAEE---------------------EMEKIEI--------------------K
TOP1_STAA8 -FKQDVERAEE---------------------EMEKIEI--------------------K
TOP1_STAAU -FKQDVERAEE---------------------EMEKIEI--------------------K
TOP1_STAAM -FKQDVERAE-------------------E--EMEKIEI--------------------K
TOP1_STAHJ -FKLDVERAEE---------------------EMEKVEI--------------------K
TOP1_STAES -FKQDVERAE-------------------S--EMEKIEI--------------------K
TOP1_BACSU -FEKRVKKAES---------------------EMKEVEI--------------------E
TOP1_HALH5 -FEERLKVAE-------------------E--EMKEVEI--------------------K
A5CVH7_VESOH -FHQKIEDAVN---------------------ISREEIH---------------------
Q28MI5_JANSC -FRAAIDETS----------------------DLRIGEV----LDKINEVLEPHLFPDPG
TOP1_XYLFT -FKELVEDKKD---------------------SLDKTDAG--------------------
TOP1_XYLFA -FKELVEDKKD---------------------SLDKTDAG--------------------
TOP1_RICTY -FNNNIESVNE------------------Q--KITEIIN-----YLQKALDYHLF----G
TOP1_RICPR -FNHNIESVNE------------------Q--KITEIIN-----YLQKALDYHLF----G
TOP1_RICBR -FNHNIESVNK------------------Q--NITEIIS-----YVQQALDYHIF----G
TOP1_RICFE -FNHNIESVNE------------------Q--KITEIIS-----YVQKALDYHLF----S
TOP1_RICCN -FNHNIESVNE------------------Q--KITEIIS-----YVQKALDYHLF----G
B7J7I8_ACIF2 -IQRILDAMPT------------------------------------------------Q
Q7WXW8_PSEAI -LQTELQTLRA----------LPSAQDEPRASSTASISS---------------------
C6XEP4_METGS -LTTELASFG----------------------GAEIPRP---------------------
B1M9R9_METRJ -LNEELARIAVSG-----------------------------------------------
TOP1P_XYLFA -LNMELSTLQV-------------------------------------------------
C8W7T0_LANP1 -LAGMIDVLID------------------HKEDLSEAIADAVT-----------------
E1RJ15_METP4 -LHEIFESLEA------------------NQEDIGSEIMDKTA-----------------
C7P1M5_HALMD -LDRVFEELADSREEVGD--------------YLQESLK---------------------
TOP1_THEAC -LHEVLSHFLT------------------KTADVKDIITKGIN-----------------
TOP1_ARCFU -LLQILRAIDYRKLSK----------------DLREGVK---------------------
B5IE55_ACIB4 -LKKILNSLEE------------------NRSTVGSNIKSS-------------------
B1L3G6_KORCO -LSAIMDEFKR------------------NELKISERLYEGLREY---------------
TOP1_AERPE -ISKLLESFLD---------------------RLDTAVR------------------EIG
A3DP02_STAMF -LIKLIVSFDK------------------KKYQIGKTLSYRLG-----------------
B8D5I1_DESA1 -LTELLGKFDR------------------N--RIEAGKQ-----LA-------------L
K0IBM4_NITGG -LIESLSAFIE------------------KEVDIGARIGNAASSSANGAQ----------
TOP1_METTH -VRSILSDIEE---------------------NLRDIGK------------------ELY
F6D5C7_METPW -VSSILDDIEK------------------N--KLKIGEE-----LYKSY----------R
TOP1_METJA -LRKILEEFKK--------KEEDIGIYLIK--NLDATNK---------------------
TOP1_PYRAB -LTKILEEFKK------------------R--ELEIGLE-----LARIVVGDVKDEIKEE
TOP1_PYRHO -LTKILEEFKK------------------RELEIGIELAKIVVGEDEV------------
Q6F0G3_MESFL ----AKTSDIKCPR--CHEGNLVFIKSKF-G-RGR---GCSNF---TT-T-KCGYRE---
F0V2L5_MYCS3 ----EIVKDKSCPE--CGS-QCVYKFSRKNHNKFI---GCIDF------P-KCKFVENIE
Q9PPP9_UREPA ----DEKINRLCPI--CAH-DLLIKRSRM-NTRFI---ACSNF------P-TCRFTESLE
TOP1_MYCGA ----EYIEGKNCPN--CSS-QLVRREGRY-G-PFV---GCSNF------P-KCKFIEKSE
TOP1_MYCPN ----KEFVGRDCPS--CAS-PLLYRYTKRGNEKFV---GCSNF------P-NCKYNEFSQ
TOP1_MYCGE ----KELVERDCPK--CNQ-PLVYRYTKRGNEKFV---GCSDF------P-KCKYSEFSN
Q3M6J7_TRIV2 ----YDTSRTRCPD--CNNFLSKIPSSKLKK-KYF--LKCT--------S-GCENTVLFW
Q4AA55_MESHJ ----ARTTGEKCTE--CDA-DLVYRYNRKTNQRFI---GCSSF------P-NCRFIK---
B3PMD8_META1 ----QEFLERSCPR--CGS-TLLYRNNSKKHTKFI---GCSNF------P-ACRYSENA-
TOP1P_MIMIV ----QSSERLLGED--NDGNEITATKTKF-G-PVVRKKIGDKY------V-YAKIKDPLT
Q8F5G0_LEPIN ----KETGWGICPV--CRNGILQKKKSSR-KKEFY---QCNRF------P-DCEFVSYEL
TOP1_BORBU SEFRTVIESQKIEN--KNSINYTINIGKY-G-PYL-IFKGHNYSINAKTPLENLYKKDEI
H8H3H1_DEIGI ----RTSPRIKVPG--REA-VFEVRDGQV--------------------TLRTADGAALL
B1VAJ5_PHYAS ----PIETDQKCNL--CNEGNLLIKKSHY-G-SFL---GCSRF------P-DCKNTSPWK
TOP1_FERIS ----DFDTDITCED--CSG-NYKLKVGKY-G-LYL---HC---------P-NCKTNKALK
TOP1_THEMA ----DFPTNQKCS---CGK-EMRLSFGKY-G-FYL---KC-----------ECGKTRSVK
B2V7T0_SULSY ----LDYAKDLAEK--HGKSIEEIKDDPEKLKEFI-----DAHAEKNPSQKQIEYAKSLA
TOP1_AQUAE ------------------------------------------------------------
D3SM80_THEAH ----------------------------------------------------------VA
G8QVT8_SPHPG ----TSKTIRLSQI--SEENPIMI--GPY-G-PYV---LGSEV--------EGKAQYLSL
TOP1_SYNE7 ----IDPAAARTVA--LEGLPAKVRIGRF-G-AYLEA-EADGE------PIKANLPKELT
TOP1_SYNY3 ----IDPAIAKAIE--LENLAAKVKIGKF-G-PYIEIPQGEEI-------ITASIPQDLT
TOP1_STRCO LGAIDAREVSSFPV----GNDIKLRVGRY-G-PYVERGEKDAE-----NHQRADVPEDLA
TOP1_MYCTU ----EVNSIKLFDD--THGRPIYVRVGKN-G-PYLERLVAGDT--GEPTPQRANLSDSIT
TOP1_MYCLE ----EVNSIKLFDD--EHGRPVYVRVGKT-G-PYLERLLAGDD--GELTPQRANLNGTLT
I0II60_PHYMF ----TEVSDHLCPT--CGS-PCEYRLGKN-G-RFL---SCTAFNVPPVEV-RPEKDPVAP
J9Z7K0_LEPFM ----EVPTEVPCPV--CQS-PMNRKWGKN-G-PYL---SCSRY------P-ECKTTRNFT
TOP1_BUCAI ----IVPTSLNCPI--CCK-KMGIKTAIT-G-VFL---SCLGYNNTDNKK-RCKKTINLI
TOP1_BUCAP ----TVPTEIDCSL--CNK-KMGIKTAVT-G-VFL---SCLGYNSEPNEK-RCKNTINLI
TOP1_PSEAE ----PTLTNIPCRE--CGR-PMMIRTAST-G-VFL---GCSGY-SLPPKE-RCKATVNLI
TOP1_VIBCH ----IVMTNILCPT--CSR-PMGIRTAST-G-VFL---GCSGY-GLPPKE-RCKTTINLG
TOP1_ECOLI ----MVLTSIDCPT--CGR-KMGIRTAST-G-VFL---GCSGY-ALPPKE-RCKTTINLV
TOP1_SALTY ----MVLTSIDCPT--CGR-KMGIRTAST-G-VFL---GCSGY-ALSPKE-RCKTTINLV
TOP1_HAEIN ----LVETDIKCPT--CGR-NMAIRTAST-G-VFL---GCTGY-ALPPKE-RCKTTINLI
TOP1_PASMU ----LVPTDINCPT--CGR-KMAIRTAST-G-VFL---GCSGY-ALPPKE-RCKTTMNLI
TOP1_CAMJE ----VTKLGESCPD--CGG-ELAIRKGRF-G-EFV---ACLNF------P-KCKYSRNLK
TOP1_HELPY ----HEKTGQSCPK--CGG-ELVKKNSRY-G-EFI---ACNNY------P-KCKYVKQTE
TOP1_HELPJ ----HEKTGQSCPK--CGG-ELVKKNSRY-G-EFI---ACNNY------P-KCKYIKQTE
TOP1_TREPA ----DEKTDVVCSQ--CGD-TMVKKLGRF-G-FFL---ACGKF------P-ECRNTQPVP
TOP1_LACLA ----DEPAGFDCDV--CGS-PMVIKLGRF-G-KFY---ACSNF------P-DCRNTKAIV
TOP1_STAS1 ----DEPAGEDCEV--CGS-PMVIKMGRY-G-KFM---ACSNF------P-DCRNTKAIV
TOP1_STAAB ----DEPAGEDCEV--CGS-PMVIKMGRY-G-KFM---ACSNF------P-DCRNTKAIV
TOP1_STAA8 ----DEPAGEDCEI--CGS-PMVIKMGRY-G-KFM---ACSNF------P-DCRNTKAIV
TOP1_STAAU ----DEPAGEDCEV--CGS-PMVIKMGRY-G-KFM---ACSNF------P-DCRNTKAIV
TOP1_STAAM ----DEPAGEDCEV--CGS-PMVIKMGRY-G-KFM---ACSNF------P-DCRNTKAIV
TOP1_STAHJ ----DEPAGEDCEV--CGS-PMVIKMGRY-G-KFM---ACSNF------P-DCRNTKAIV
TOP1_STAES ----DEPAGEDCEV--CGS-PMVIKMGRY-G-KFM---ACSNF------P-DCRNTKAIV
TOP1_BACSU ----PEYAGEDCEL--CSS-PMVYKMGRY-G-KFL---ACSNF------P-DCRNTKPIV
TOP1_HALH5 ----DEPTGEMCEK--CGH-EMVYKMGRY-G-KFM---ACSNF------P-DCRNTKPIV
A5CVH7_VESOH ----SMRNLGVDPK--SDK-PVSVRVGRY-G-AFVQI-GHTDD--------KDKPTFASF
Q28MI5_JANSC ----DGTDPRLCPN--CGVGRLSMRTARAGG-AFI---GCSAY------P-ECRYTRPFG
TOP1_XYLFT ----SVRLLGIDPT--SGK-EVSARIGRF-G-PMVQIGTVDDE------E-KPRFASLRP
TOP1_XYLFA ----SVRLLGIDPT--SGK-EVSGRIGRF-G-PMVQIGTVDDE------E-KPRFASLRP
TOP1_RICTY ----ENKESKVCPS--CKTGQLSLKLGKF-G-AFL---ACSNY------P-ECTFKKSIV
TOP1_RICPR ----EDKESKVCPS--CKTGQLSLKLGKF-G-AFL---ACSNY------P-ECTFKKSIV
TOP1_RICBR ----ENKDSKVCPS--CKTGELSLKLGKF-G-AFL---ACSNY------P-ECNFRKSIV
TOP1_RICFE ----ENKESKACPS--CKTGELSLKLGKF-G-AFL---ACSNY------P-ECTFRKSIV
TOP1_RICCN ----ENKESKICPS--CNTGELSLKLGKF-G-AFL---ACSNY------P-ECTFRKSIV
B7J7I8_ACIF2 ----ARAQGRPCPIEGCDGTVRRLESKRKPGVFFW---MCSNR--------DAHPLLQDN
Q7WXW8_PSEAI ----APTSDFLCGK--CGLPLVHRKKAGKGGFDFW---GCSGY-----RTTGCKVSYPTK
C6XEP4_METGS ----APSTVGSCPK--CGK-GMVQRTGSR-G-PFL---GCSGY------P-KCKETQQLP
B1M9R9_METRJ ----EFTPRFKCPK--CGTG--MRRYAKPGKSPFW---RCTAE------AETCGHYMDDD
TOP1P_XYLFA ----SATPKHPCQE--CGK-PLRRIPGKN-G-HFW---GCSGY------P-DCSVTFPDE
C8W7T0_LANP1 ----ADAKVGTCPK--CGKDLVAKSSLKTRG-SFV---GCMGW------P-DCDVTYPLP
E1RJ15_METP4 ----EERVVGKCPV--CGK-SLMIRTTKGMA-QFI---GCTGY------P-DCSFNIGLP
C7P1M5_HALMD ----ADKTLGPCPE--CGE-DLLVRRSRQ-GSYFV---GCDGF------P-ECRFTLPLP
TOP1_THEAC ----AGQEIGDCPF--HEGKKIMVIRDRF---TYT--VRCEDP--------SCKINFRIK
TOP1_ARCFU ----KDKIVGKCPE--CGG-ELVVRQSKA-GKRFI---GCSNY------P-DCTFTLPLP
B5IE55_ACIB4 ----MRREIGECPD--GGK---LIYLERK---RLV---VCEND--------GETKYYNLP
B1L3G6_KORCO ----RSGSLGKCPE--CGG-DLNMRKSSY-G-YFI---VCSNY------PEKCDVKFNLF
TOP1_AERPE VSLGSVEVEAACHL--CGRKAVSAVSGYR---------LCSHH-----MEAFDRLRKALP
A3DP02_STAMF ----YITPINKCIL--CNREAYKNNLCKY---HYR----------------ALNTVIKTY
B8D5I1_DESA1 ----RLKIIQNTRK--CRV-SSCYREGVVNG-------LCSHH------ANAVKLVREYY
K0IBM4_NITGG ----AATMIGSCPV--CKKGQLRMIKSYKTKKRFV---GCSNY------SGGCKATAPLP
TOP1_METTH RAYQDSRVVGECPA--CGG-KLVIKYSPRNRSTFV---GCSSY------P-DCRTVYSLP
F6D5C7_METPW ----ESRVVGKCK---CGKNLILIDSPR--GSTFV---GCSGY------P-ECKSTYSMP
TOP1_METJA ----KAKIVGKCPK--CGGDLILIRHKKG---RFV---GCSNY------P-ECDVKYSLP
TOP1_PYRAB ----KPIVVGKCPK--CGG-DLIVKYNKKTGKRFV---GCSNW------P-KCDVTYPIL
TOP1_PYRHO ----KPLVVGKCPK--CGG-DLIVKYNKKTGKRFV---GCSNW------P-KCDVTYPIL
Q6F0G3_MESFL ------------------------------------------------------------
F0V2L5_MYCS3 QPQKEVELLD--------------------KLCSECKSPLAKKKNRWGNEFIS-------
Q9PPP9_UREPA KPEILNE-----------------------------------------------------
TOP1_MYCGA QKAKEIVYEE--------------------------------------------------
TOP1_MYCPN NKPNLTLEKL--------------------------------------------------
TOP1_MYCGE PKPKLTLETL--------------------------------------------------
Q3M6J7_TRIV2 SEFSKTWQA---------------------------------------------------
Q4AA55_MESHJ ------------------------------------------------------------
B3PMD8_META1 ------------------------------------------------------------
TOP1P_MIMIV LDTIKLSDAI--------------------------------------------------
Q8F5G0_LEPIN PESLE-------------------------------------------------------
TOP1_BORBU EKIINEKELK--------------------------------------------------
H8H3H1_DEIGI PAELLPEDLD--------------------------------------------------
B1VAJ5_PHYAS VQEKNKSKDS--------------------------------------------------
TOP1_FERIS SDVFGVIDGN--------------------------------------------------
TOP1_THEMA NDEIAVIDDG--------------------------------------------------
B2V7T0_SULSY EKTGLKLTEK--------------------------------------------------
TOP1_AQUAE ------------------------------------------------------------
D3SM80_THEAH PEEELPSSTS--------------------------------------------------
G8QVT8_SPHPG PLDWTPGNITDEDVKALIARGKVKAEPEILGTGKVAGLPVQLLNGRFGPYWQE-------
TOP1_SYNE7 PADLDVQRVE-------TLLRQKTEGPDQLGTHPETDEPIYLLTGAYGPYVQL-------
TOP1_SYNY3 PADLNPEQVA-------VLLKQKTEGPDKVGIHPETGEPIFILIGAYGPYVQL-------
TOP1_STRCO PDELSVELAEELLAKPSGDFE--------LGTDPATGHAIVAKDGRYGPYVTE-------
TOP1_MYCTU PDELTLQVAEELFATPQQGRT--------LGLDPETGHEIVAREGRFGPYVTE------I
TOP1_MYCLE PDELTLEVAEELFATPHEGRV--------LGVDPETGHEIVAKDGRYGPYVTEVLPKHDD
I0II60_PHYMF DGSPWLLHKAKGKARPKITTA--------DGETKLGWTKLSKTDKERFMNLSE-------
J9Z7K0_LEPFM EEDGQIRIVE------EALPE--------GEVCHVCQAPMVIKKGRFGTFLAC-------
TOP1_BUCAI TLNDFNKEQD--NQKKISLQL--------IQKCDICNMYMDSYFINEKLKLHI-------
TOP1_BUCAP SLNDLSTTKK--EEKNFHLK----------NRCKKCNLVMDVYLINENLKIFI-------
TOP1_PSEAE PGDEIAADDE-GESESRVLRG--------KHRCPICSTAMDAYLLDEKHKLHI-------
TOP1_VIBCH DEEGVINVLE-EDVETAALRA--------KKRCPICETAMDAYLIDDKRKLHV-------
TOP1_ECOLI PENEVLNVLEGEDAETNALRA--------KRRCPKCGTAMDSYLIDPKRKLHV-------
TOP1_SALTY PENEVLNVLEGDDAETNALRA--------KRRCQKCGTAMDSYLIDPKRKLHV-------
TOP1_HAEIN PEAELLNVLD-ESSETKALMD--------RKRCTKCGTAMDSYVIDAHRKIHI-------
TOP1_PASMU PEAELLNVLD-EASETKALME--------RKRCPKCGTAMDSYLIDPERKIHI-------
TOP1_CAMJE SESKNESENT--------------------------------------------------
TOP1_HELPY SANDEADQ----------------------------------------------------
TOP1_HELPJ NANDEAKQ----------------------------------------------------
TOP1_TREPA ------------------------------------------------------------
TOP1_LACLA KE----------------------------------------------------------
TOP1_STAS1 KT----------------------------------------------------------
TOP1_STAAB KS----------------------------------------------------------
TOP1_STAA8 KS----------------------------------------------------------
TOP1_STAAU KS----------------------------------------------------------
TOP1_STAAM KS----------------------------------------------------------
TOP1_STAHJ KT----------------------------------------------------------
TOP1_STAES KT----------------------------------------------------------
TOP1_BACSU KQ----------------------------------------------------------
TOP1_HALH5 KE-------I--------------------------------------------------
A5CVH7_VESOH RGLLDIESIT--------------------------------------------------
Q28MI5_JANSC PPDPEAEASA--------------IPPDGKLLGEDQGDEIRIFKGRFGPYVQR-------
TOP1_XYLFT NQSIYSISLE--------------------------------------------------
TOP1_XYLFA NQSIYSISLE--------------------------------------------------
TOP1_RICTY SGNDNNEDEG--------------------------------------------------
TOP1_RICPR SGNDNNEDEG--------------------------------------------------
TOP1_RICBR SGNDNNEADG--------------------------------------------------
TOP1_RICFE SGNDNNENDG--------------------------------------------------
TOP1_RICCN SGNDNNENEG--------------------------------------------------
B7J7I8_ACIF2 DGEPGAPFAE--------------------------------------------------
Q7WXW8_PSEAI SG----------------------------------------------------------
C6XEP4_METGS KGA---------------------------------------------------------
B1M9R9_METRJ KGKPVERTAH---------------------PCPRCGETLRRFKRK--------------
TOP1P_XYLFA GGKPGQKKPV--------------------------------------------------
C8W7T0_LANP1 QGRVEPLEGE--------------------------------------------------
E1RJ15_METP4 SGQWGKAIRDNKICEIHGMNHIRLVRKGSPPWDLGCPLCNHISSNLETLNMIP-------
C7P1M5_HALMD STGEPQVLDDSCEDHGLNHVKMLAGRDTFVHGCPRCEAE---------------------
TOP1_THEAC RNGSITLSDQ--------------------------------------------------
TOP1_ARCFU QNGTLYITAK--------------------------------------------------
B5IE55_ACIB4 KTGHIEFLDK--------------------------------------------------
B1L3G6_KORCO KNERFEGKFC--------------------------------------------------
TOP1_AERPE NLASTISSTP--------------------------------------------------
A3DP02_STAMF DEWKRREGVD--------------------------------------------------
B8D5I1_DESA1 GEWSRRKDIT--------------------------------------------------
K0IBM4_NITGG QKGAIRVLGK--------------------------------------------------
TOP1_METTH RGASVL------------------------------------------------------
F6D5C7_METPW RGATVL------------------------------------------------------
TOP1_METJA DKGRIKIPNKVCDACKSPILKIGDREICINPECPLKQVEVKE------------------
TOP1_PYRAB QRGEIIPTNK--------------------------------------------------
TOP1_PYRHO QRGEIIPTNK--------------------------------------------------
Q6F0G3_MESFL ------------------------------------------------------------
F0V2L5_MYCS3 -------------------------------CSNYPKCKYIERNKQEYETVENSFCPE-C
Q9PPP9_UREPA ------------------------------------------------------LCPN--
TOP1_MYCGA ----------------------------------------------------GVKCEL--
TOP1_MYCPN ----------------------------------------------------EELCPE--
TOP1_MYCGE ----------------------------------------------------DELCPE--
Q3M6J7_TRIV2 -----------------------------------------------------------P
Q4AA55_MESHJ -----------------------------------------------------------V
B3PMD8_META1 ------------------------------------------------------------
TOP1P_MIMIV ----------------------------------------------KLLEYPKNLGQY--
Q8F5G0_LEPIN ------------------------------------------------------------
TOP1_BORBU ---------------------------------------------------PNILGVD-P
H8H3H1_DEIGI ------------------------------------------------------------
B1VAJ5_PHYAS ----------------------------------------------DHSNQTDQKCNL-C
TOP1_FERIS -----------------------------------------KLYVLEEQESQEENGEKNS
TOP1_THEMA ---------------------------------------------------KIFLGRKDS
B2V7T0_SULSY ------------------------------------------------ELLDRKLLTKWI
TOP1_AQUAE ------------------------------------------------------------
D3SM80_THEAH ------------------------------------------------------------
G8QVT8_SPHPG ------------------GEGKDAKRASIPKWVMDAEKQHELEIANRYLSLPRLLGKD--
TOP1_SYNE7 --------------G--AATEEKPKPKRASLPKGMSLETISLEQAVGLLSLPRTLGEH-P
TOP1_SYNY3 --------------G--EATEENKKPKRTSLPKGVKPEDVTLEMAVGLLALPRNLGEH-P
TOP1_STRCO ----------VLPEGTPKTGKNAVKPRTASLFKSMSLDTVTLDDALKLMSLPRVVGAD--
TOP1_MYCTU LPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVD-P
TOP1_MYCLE DYGAADQGTKKTKKGRRASASQGPKPRTGSLLRSMDLQTITLEDALKLLLLPRVVGVD-P
I0II60_PHYMF -------------------------QMPEPCKYACPIDRNGNPQAPELTD---VLCPV--
J9Z7K0_LEPFM -------------------------SRYPACKTTRPWPPKTEASLPAVRPADAPSCPE-C
TOP1_BUCAI -------------------------CANNPSCSGYKF-EKGVFKSPIYLS-KTIQCEK-C
TOP1_BUCAP -------------------------CINNPSCNGYNL-KKGIFKKSLNCSLKKIKCEK-C
TOP1_PSEAE -------------------------CGNNPDCPGYEI-EEGQYRIKGYEG-PSLECDK-C
TOP1_VIBCH -------------------------CGNNPNCEGFIV-EEGEFKVKGYEG-PTVECDK-C
TOP1_ECOLI -------------------------CGNNPTCDGYEI-EEGEFRIKGYDG-PIVECEK-C
TOP1_SALTY -------------------------CGNNPTCDGYEI-EEGEFRIKGYDG-PIVECEK-C
TOP1_HAEIN -------------------------CGNNPNCDGYLI-EEGSFKIKGYDG-PVVECDK-C
TOP1_PASMU -------------------------CGHNPNCDGYVL-EQGSFKIKGYDG-PIVECDK-C
TOP1_CAMJE -------------------------------------------AAKAKANGTGITCPS-C
TOP1_HELPY -----------------------------------------------------ELCEK--
TOP1_HELPJ -----------------------------------------------------ELCEK--
TOP1_TREPA ----------------------------------------------------LAKCPRPA
TOP1_LACLA ---------------------------------------------------IGVKCPL-C
TOP1_STAS1 ---------------------------------------------------IGVTCPK-C
TOP1_STAAB ---------------------------------------------------IGVKCPK-C
TOP1_STAA8 ---------------------------------------------------IGVKCPK-C
TOP1_STAAU ---------------------------------------------------IGVKCPK-C
TOP1_STAAM ---------------------------------------------------IGVKCPK-C
TOP1_STAHJ ---------------------------------------------------IGVTCPK-C
TOP1_STAES ---------------------------------------------------IGVTCPK-C
TOP1_BACSU ---------------------------------------------------IGVKCPS-C
TOP1_HALH5 ----------------------------------------------------GVKCPK-C
A5CVH7_VESOH -----------------------------------------LDEALELFNMPRHLGET--
Q28MI5_JANSC --------------G--AMTEENKKPPRQSIPKDWTPEELDLERALMLLSLPRQIGPH-P
TOP1_XYLFT -------------------------------------------EAIELFKMPRVLGED--
TOP1_XYLFA -------------------------------------------EAIELFKMPRVLGED--
TOP1_RICTY -------------------------------------------NLSTILNDNKILGTD--
TOP1_RICPR -------------------------------------------DPSTILNDNKILGTD--
TOP1_RICBR -------------------------------------------EAKDIVNENKVLGKD--
TOP1_RICFE -------------------------------------------DLAATPNENKVLGTD--
TOP1_RICCN -------------------------------------------EPAAMPNENKVLGTD--
B7J7I8_ACIF2 ----------------------------------------------RVEAGDGPACPE--
Q7WXW8_PSEAI ------------------------------------------------------------
C6XEP4_METGS ------------------------------------------------------------
B1M9R9_METRJ -------------------------NGGGLVWVCPAEACETFLDDVGGKPVALHTCTK-C
TOP1P_XYLFA -------------------------------------------------EVSNFACVK-C
C8W7T0_LANP1 ----------------------------------------------------AGVCPE-C
E1RJ15_METP4 ----------------SISKDLISNLHSHNIYTVYEIANENPEKLSKVTGISKEDSEKLI
C7P1M5_HALMD -------------------------------------------KADETDDEVIGACPE-C
TOP1_THEAC ------------------------------------------------------KCPV-C
TOP1_ARCFU ------------------------------------------------------QCKE--
B5IE55_ACIB4 ------------------------------------------------------KCPI-C
B1L3G6_KORCO ------------------------------------------------------ECGL-P
TOP1_AERPE -----------------------------------------------------------R
A3DP02_STAMF ------------------------------------------------------------
B8D5I1_DESA1 -----------------------------------------------------------F
K0IBM4_NITGG ------------------------------------------------------ACPE-C
TOP1_METTH ----------------------------------------------------KSLCEK-C
F6D5C7_METPW ----------------------------------------------------KTTCEE-C
TOP1_METJA ---------------------------------------------------EDRICPK--
TOP1_PYRAB ----------------------------------------------------------TC
TOP1_PYRHO ------------------------------------------------------TC---C
Q6F0G3_MESFL -----YEQRDGS--------WLEYVAKPK-------------------------------
F0V2L5_MYCS3 NSQLVYKNSKRK--------GNKFIACSG---------FPNCRYSSTLEGKRIE------
Q9PPP9_UREPA CSKSLVKRKNRK--------NKYFIGCTG-------------------------------
TOP1_MYCGA -CHAKLIRRVAK------------------------------------------------
TOP1_MYCPN -CNSQLVKRRTK--------FNPNKTFVG-------------------------------
TOP1_MYCGE -CNNKLVKRRTK--------FNAKKTFIG-------------------------------
Q3M6J7_TRIV2 RTKDDKMAENGQ--------KNHLSPATK---------LP--------------------
Q4AA55_MESHJ DENAKKVYRFRK--------RNTKILTNK-------------------------------
B3PMD8_META1 -DGTPTGQKTYK--------PRYYKKSSK-------------------------------
TOP1P_MIMIV -KGFDVLLQKGD--------YGFYLSYNK-----------------------------EN
Q8F5G0_LEPIN ------------------------------------------------------------
TOP1_BORBU LTGLNVIFKNTI--------YGNIVQLGEDTHAPQEYTKKGKPKKLKIIKAKKAST----
H8H3H1_DEIGI -ERSIPALLAGT--------WKPSLKSTR-------------------------------
B1VAJ5_PHYAS NEGNLLIKKSR---------YGSFLGCSR-------------------------------
TOP1_FERIS VQSEESSANSGN---------RKFYRKRR-------------------------------
TOP1_THEMA ESGSPDGRSVEG--------KGNLSE----------------------------------
B2V7T0_SULSY NKAKKEMMKNYQ--------LSEKQKNV--------------------------------
TOP1_AQUAE ------------------------------------------------------------
D3SM80_THEAH ------------------------------------------------------------
G8QVT8_SPHPG KDGNDIVAAKGK--------FGPFISCNGEFRNLRKTDHDAQLFSITLEEALALLAEEKP
TOP1_SYNE7 ETGRRIQAGLGR--------FGPYVVCDL---------GGGEKDYRSLKADDDVLTIDLD
TOP1_SYNY3 ESGKNIKASLGR--------FGPYVVHDQ---------GKDGKDYRSLKGDDDVLTITLE
TOP1_STRCO AEGVEITAQNGR--------YGPYLKKGT--------------DSRSLQTEDQLFEITLE
TOP1_MYCTU ASGEEITAQNGR--------YGPYLKRGN--------------DSRSLVTEDQIFTITLD
TOP1_MYCLE ASGEEITAQNGR--------YGPYLKRGK--------------DSRPLTTEDQMFIITLD
I0II60_PHYMF -DGEPMIQRTGR--------FGPFLASSN---------YPAVQYILKLHPKTG-------
J9Z7K0_LEPFM --SSTMVQKRGR--------FGSFWACSR---------YPE-------------------
TOP1_BUCAI --YNNMKLKIGP--------FGKFFTCIN---------KICKNTRKILPNG---------
TOP1_BUCAP --KNDMLFKTGR--------FGNFFMCIN---------DTCKNTRKILPNG---------
TOP1_PSEAE --GSEMQLKTGR--------FGKFFGCTN---------PTCKNTRKLLKNG---------
TOP1_VIBCH --GSDMVLKNGR--------FGKYMGCTN---------DACKNTRKILKNG---------
TOP1_ECOLI --GSEMHLKMGR--------FGKYMACTN---------EECKNTRKILRNG---------
TOP1_SALTY --GSEMHLKMGR--------FGKYMACTN---------DECKNTRKILRNG---------
TOP1_HAEIN --GADMHLKLGR--------FGKYMGCTN-----------CDNTRKILKNG---------
TOP1_PASMU --GADMHLKLGR--------FGKYMGCTS-----------CDNTRKILKSG---------
TOP1_CAMJE QKGEIVERFSKR---------GKFYGCSA---------YPK-------------------
TOP1_HELPY -CGGEMVQKFSR--------NGAFLACNN---------YPECKNTKSL------------
TOP1_HELPJ -CGGEMVQKFSR--------NGAFLACNN---------YPECKNTKSL------------
TOP1_TREPA CDGNIVGKKTRG--------RKEFYGCTR-------------------------------
TOP1_LACLA HEGNIIERKTKK--------NRIFYGCDR---------YPD-------------------
TOP1_STAS1 KEGDVVERKSKK--------NRIFYGCSK---------YPE-------------------
TOP1_STAAB NDGDVVERKSKK--------NRVFYGCSK---------YPE-------------------
TOP1_STAA8 NDGDVVERKSKK--------NRVFYGCSK---------YPE-------------------
TOP1_STAAU NDGDVVERKSKK--------NRVFYGCSK---------YPE-------------------
TOP1_STAAM NDGDVVERKSKK--------NRVFYGCSK---------YPE-------------------
TOP1_STAHJ KDGDVVERKSKK--------NRLFYGCSN---------YPE-------------------
TOP1_STAES NEGDVVERKSKK--------NRIFYGCSR---------YPE-------------------
TOP1_BACSU GEGNIVERKSKK--------KRVFYGCDR---------YPD-------------------
TOP1_HALH5 EKGEIVERKSKK--------RRVFYGCNQ---------YPE-------------------
A5CVH7_VESOH DNFGTIKANYGR--------FGPYIQYGK-------------------------------
Q28MI5_JANSC EDGIMVWSNIGR--------YGPYLKHAESTSDRGGTNANLDGLDEVFTVGMNRAVQLLA
TOP1_XYLFT -QSQQVSVGIGR--------FGPFAKRGS-------------------------------
TOP1_XYLFA -QSQQVSVGIGR--------FGPFAKRGS-------------------------------
TOP1_RICTY KDGVEIYLKTGP--------YGPYIQLGE---------Q-CGKVKPKRTPVPTNLKQS--
TOP1_RICPR QDGVEIYLKKGP--------YGPYIQLGE---------Q-CGKVKPKRTPVPANLKQS--
TOP1_RICBR KEGIEIYLKKGP--------YGPYIQYGE---------QVDSKIKPKRSPLPAGLNQN--
TOP1_RICFE KDGIEIYLKKGP--------YGPYVQLGE---------Q-EGKVKPKRSPVPASLNQN--
TOP1_RICCN KDGVEIYLKKGP--------YGPYIQLGK---------Q-EGKVKPKRSPVPASLNQN--
B7J7I8_ACIF2 CGAATSRQETGK--------GYGYFRCGK-------------------------------
Q7WXW8_PSEAI --RPDFDNPRGL------------------------------------------------
C6XEP4_METGS ------------------------------------------------------------
B1M9R9_METRJ NAPLRRYQKKDRETGKPTGAFGWFCTDTE-----------------------------N-
TOP1P_XYLFA GNPLKHLVKKGK-------GGYDFWGCSG-------------------------------
C8W7T0_LANP1 GAPRVKVQPFRQ---------RAYETCIN-------------------------------
E1RJ15_METP4 READEVLELLRK--------RSELKKFVRKIIPPKRGRSHAKVLNMFFDAGIVDMESL--
C7P1M5_HALMD GEGAAPEEQRGE--------GGDSEAQSA-------------------------------
TOP1_THEAC GLPMIKIIRKGQ---------SPEIKCID-------------------------------
TOP1_ARCFU HEIKEVKIRTKK--------GYWNLGCPY-------------------------------
B5IE55_ACIB4 GLSLIKIIRRGQ---------SPEIRCLD-------------------------------
B1L3G6_KORCO LVSGRIKTKSNR--------GRGYTRCIA-------------------------------
TOP1_AERPE EALEAIARGRSR--------AGAWVRDVA-------------------------------
A3DP02_STAMF --------------------WNKYLSSIK-------------------------------
B8D5I1_DESA1 NEYIDKLRKSKL--------TGKWVKEVI-------------------------------
K0IBM4_NITGG GWPIVGVVFARR--------SKHWKICVN-------------------------------
TOP1_METTH GLPMISYGRPRQ------------RACLD-------------------------------
F6D5C7_METPW GLPMISFGKPRQ------------RACLDP------------------------------
TOP1_METJA -CGAKLILKKGV--------YGAFYGCSN-------------------------------
TOP1_PYRAB CNGAPVVIIRDK--------GRDIEICLD-------------------------------
TOP1_PYRHO NGAPVVIIREED--------GREFEICLD-------------------------------
Q6F0G3_MESFL ------------------------ETK---------------------------------
F0V2L5_MYCS3 -----------SKGNSKSNKPPEKLDRKCPKCK------KNYLQ---------IKMSRKG
Q9PPP9_UREPA ------------------------------------------------------------
TOP1_MYCGA -----------------------------------------------------KKGRNKD
TOP1_MYCPN ------------------------------------------------------------
TOP1_MYCGE ------------------------------------------------------------
Q3M6J7_TRIV2 -----------TQLTAYPCPV-------CKR-PL-----EEY-T---------YTKDGQK
Q4AA55_MESHJ ------------------------------------------------------------
B3PMD8_META1 ----------------------------AN------------------------------
TOP1P_MIMIV FSL--------GEIDDPEDINLDTAIKAIEAKKANNI--AEFNLTENGKKIKAIVLNGKY
Q8F5G0_LEPIN ------------------------------------------------------------
TOP1_BORBU -----------KKIDPENITLELALKLLSLPKPIGKHPQTNEQI---------IAATGVF
H8H3H1_DEIGI ------------------------------------------------------------
B1VAJ5_PHYAS ------------------------------------------------------------
TOP1_FERIS ------------------------------------------------------------
TOP1_THEMA -----------------------------------------------------KRRKGKK
B2V7T0_SULSY -----------------------------------------------------LIKYGRE
TOP1_AQUAE ------------------------------------------------------------
D3SM80_THEAH ------------------------------------------------------------
G8QVT8_SPHPG KA---------GAKGKGKGSSSSAVVRQIG--EF-----EKEPV---------ALAIGRY
TOP1_SYNE7 RALEL------LAQPKKSRGRGKEPIREVGLHPD-----DQAPI---------QIFEGPY
TOP1_SYNY3 RALE-------LLAEPKRGRGSRTPLKQLGLHPE-----DQEPV---------NLFKGPY
TOP1_STRCO EALAIY-----AQPKQRGRAAAKPPLKELGTDPV-----SEKPV---------VVKDGRF
TOP1_MYCTU EALKIYA----EPKRRGRQSASAPPLRELGTDPA-----SGKPM---------VIKDGRF
TOP1_MYCLE EALKIYA----EPKRAGRQSTSPPPLRELGTDPT-----SGKPM---------LIKDGRF
I0II60_PHYMF -----------AVVTPKVEPL-VTEMV-CP--KC-----EERPL---------NLRDGKH
J9Z7K0_LEPFM -----------CKGTRPLAT----GLP-CPVQGC-----KGE-L---------VPRRGKR
TOP1_BUCAI -----------EISDPKLEPIPFPELL-CK--QS-----DAW-F---------VLREGIS
TOP1_BUCAP -----------EISEPKFEPIPFPDIL-CE--KS-----NTW-F---------VLREGIS
TOP1_PSEAE -----------EAAPPKMDAIRMPELK-CE--KV-----DDI-Y---------VLRDGAS
TOP1_VIBCH -----------EVAPPKEEPVHFPELP-CE--NS-----DAY-F---------VLRDGAS
TOP1_ECOLI -----------EVAPPKEDPVPLPELP-CE--KS-----DAY-F---------VLRDGAA
TOP1_SALTY -----------EVAPPKEDPVPLPELP-CE--KS-----DAY-F---------VLRDGAA
TOP1_HAEIN -----------EVAPPKEEPVHFPELK-CE--KS-----DAY-F---------VLRDGAS
TOP1_PASMU -----------EVAPPKEEPTHFPELK-CE--KS-----DAY-F---------VLRDGAS
TOP1_CAMJE -----------CNFISKYKPSEEK----CE--EC-----GETLV----------IKELKK
TOP1_HELPY -----------KNTPNAKETIEGVKCPECG---------GDI-----------ALKRSKK
TOP1_HELPJ -----------KNTPNAKETI---EGVKCP--EC-----GGD-I---------ALKRSKK
TOP1_TREPA ------------FPVCDFVTHFKPTFAVCPQCRC-------FLV---------EKSNRRV
TOP1_LACLA -----------CEFTSWDKPI----GRDCP--KS-----GHFLV---------EKKVRGG
TOP1_STAS1 -----------CDFVTWDKPI----GRDCP--KC-----EHYLV---------EKKQGRK
TOP1_STAAB -----------CDFISWDKPI----GRDCP--KC-----NQYLV---------ENKKGKT
TOP1_STAA8 -----------CDFISWDKPI----GRDCP--KC-----NQYLV---------ENKKGKT
TOP1_STAAU -----------CDFISWDKPI----GRDCP--KC-----NQYLV---------ENKKGKT
TOP1_STAAM -----------CDFISWDKPI----GRDCP--KC-----NQYLV---------ENKKGKT
TOP1_STAHJ -----------CDFISWDKPV----GRDCP--KC-----NHYLM---------EHKKGRS
TOP1_STAES -----------CDFISWDKPV----GRDCP--KC-----HHYLV---------NKKKGKS
TOP1_BACSU -----------CEFVSWDKPIERK----CP--KC-----GKMLV----------EKKLKK
TOP1_HALH5 -----------CDFVSWDKPIARS----CP--KC-----SSY-L---------VEKRTKK
A5CVH7_VESOH ------KYVSLKEDIPEEVSLEKALELIKIKEKF-----DSERIIKIFDGSDIQLLNGRF
Q28MI5_JANSC E----------KVASRGGRGQAAKPLRELGEHPD-----AGGPV---------NVMKGKY
TOP1_XYLFT ----------TYVSLKSEDDPYTIDLARATLLINEKEEIARNRIIKDFENSQIQVLNGRF
TOP1_XYLFA ----------TYVSLKSEDDPYTIDLARATFLINEKEEIARNRIIKNFENSQIQVLNGRF
TOP1_RICTY -----------EITLEVALKLLSLPLK-IGIHKD-----SGEEI---------IIGYSKF
TOP1_RICPR -----------EITLEIALKLLNLPLK-IGIHKD-----SGEEI---------IIGYSKF
TOP1_RICBR -----------DITLDMALKLLSLPLK-IGNHKE-----SGEEV---------LVGYGKF
TOP1_RICFE -----------DITLEMALKLLSLPLK-IGIHKD-----SGEEI---------MIGYGKF
TOP1_RICCN -----------DITLDIALKLLSLPLK-IGIHKD-----SDEEI---------MIGYGKF
B7J7I8_ACIF2 -----------GHGSWWDDKGSLGKKW--------------------------EDRAPAQ
Q7WXW8_PSEAI ------------------------------------------------------------
C6XEP4_METGS ------------------------------------------------------------
B1M9R9_METRJ -----------CKTFMDDDKGRPVAIKTAPCPKC-----GKAMY----------RRKGDH
TOP1P_XYLFA ------------------------------------------------------FKEG--
C8W7T0_LANP1 ---------------PACPTNSEPDLIVGECPTCKANGKHGDLV---------AHKSERT
E1RJ15_METP4 -----------ARADKKTLEKMKLSAEEAESLSHEARLVYNKALLKEYGVPAVSLKKYFD
C7P1M5_HALMD -----------SDHSSGQSPREETAEAH-----------GGKLA---------IKRLRSG
TOP1_THEAC --------------PDCSYNRENEDYGECP--AD-----HGRLV---------LRQSKYG
TOP1_ARCFU ------------------------------------------------------------
B5IE55_ACIB4 --------------SKCEYNRKKDVVGKCP--KC-----GGDLV---------IRQSKNG
B1L3G6_KORCO -------------------NCDRTPLRCAK---------CGGPM---------VAKQGKF
TOP1_AERPE ------------------------ALA--------------------------LRDDGLY
A3DP02_STAMF -------------------------------------------------------KLKST
B8D5I1_DESA1 ---------------------------------------ESELT----------------
K0IBM4_NITGG --------------------------MQCPSKKK--------------------------
TOP1_METTH -----------PKCGKKKSEVEEVVGK-CP--EC-----GSDLI----------KRSGRY
F6D5C7_METPW -----------KCGKDGREPTNEVVGK-CP--DC-----GSD-L---------IKRSGRY
TOP1_METJA -----------YPKCKYTEPINKKEVV-GKCPKC-----GGDLV----------VREGKF
TOP1_PYRAB -------------------------------IKC-----KKW------------------
TOP1_PYRHO ------------------------------------------------------------
Q6F0G3_MESFL ------------------------------------------------------------
F0V2L5_MYCS3 TKFIS----CSGYP---R----CKYVEWMDKEGETENKSS--------------------
Q9PPP9_UREPA ------------YP---E----CNFIRNLDESNNDKNDFNQ-------------------
TOP1_MYCGA NTFLG----CSNFP---K----CKYTKSLEPEKDETIRDSTII-----------------
TOP1_MYCPN ---------CSNFP---R----CRYIKKDNAS----------------------------
TOP1_MYCGE ---------CSNFP---N----CRFIKKDNAAEFKQ------------------------
Q3M6J7_TRIV2 KTMLR----CSASS---S----RT--DKKHQDVAYFHTAKGWWSPKFGEINK--------
Q4AA55_MESHJ ------------------------------------------------------------
B3PMD8_META1 ------------------------------------------------------------
TOP1P_MIMIV GYYVQVTRNRIKKN--------YPIPKDLDPNNLTEQQILSIISVKKTYKKSAPK-GGSK
Q8F5G0_LEPIN ------------------------------------------------------------
TOP1_BORBU GDYIKTESGSIA----------CSLKKDLKAYDITLDKAISLLNERANKVGIIVK-TITF
H8H3H1_DEIGI ----------------------RTDGETAPSAAPAAKRKSSTTPRKKRDSTASPR-KKTS
B1VAJ5_PHYAS ------------FP---D----CKNIVKIKNKPNSK------------------------
TOP1_FERIS ----------------------TSGSKKSSTKSASSKAKKK-------------------
TOP1_THEMA GS----------------------------------------------------------
B2V7T0_SULSY DLV-------------------NNPVQALKFIKSKLSRYKK-------------------
TOP1_AQUAE ------------------------------------------------------------
D3SM80_THEAH ------------------------------------------------------------
G8QVT8_SPHPG GYYLKVGKDNIALP---P----KYKHDDELAKAISLEDAAEIIRTKRAKDSEE-------
TOP1_SYNE7 GLYLKHGKVNASLP---E---------DEKPETISLETAVAALAAKAGQAKAKGG-RRST
TOP1_SYNY3 GVYIKHGKVNASLP---EGETEETITLEKALPLLAEKAGSGKKTSRKKATTTAKGTKKTT
TOP1_STRCO GPYVTDGETNATLR---SDDSVEEITPERGYELLAEKRAKGPAKKTAKKAVKKTAAKKAP
TOP1_MYCTU GPYVTDGETNASLR---KGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAA
TOP1_MYCLE GPYVTDGETNASLR---KGDDVVSITDERAAELLADRRARGPVKRPAKKARKVPAKKAAR
I0II60_PHYMF GLWLG----CSGFP---K----CR--GREGFTKLPEEEQADLTKLWEKHVKEHPL-PEVK
J9Z7K0_LEPFM GTFYG----CSRYP---E----CTFLLNGEPVRDPCPDCQF-------------------
TOP1_BUCAI GIFFA----ANTFP---K----SR--ETRSPFVEELVRFQHLLPEKIYYLSSAPV-IDNY
TOP1_BUCAP GIFFA----ANTFP---K----SR--ETRSPFVEELARFEYLLPKKLHYLASAPQ-RDNK
TOP1_PSEAE GMFLA----ASQFP---K----NR--ETRAPLVSEIIPHKAELDPKYHYLCDAPQ-KDPD
TOP1_VIBCH GLFFA----ASNFP---K----SR--ETRAPLVEELKRFAERLPEKYQYLTSAPA-HDPD
TOP1_ECOLI GVFLA----ANTFP---K----SR--ETRAPLVEELYRFRDRLPEKLRYLADAPQ-QDPE
TOP1_SALTY GIFLA----ANTFP---K----SR--ETRAPLVEELYRFRDRLPEKLRYLADAPQ-QDPE
TOP1_HAEIN GVFMS----AHNFP---K----SR--ETRPVKIAELVQYRERLPEKLAYLADAPQ-KDPE
TOP1_PASMU GVFMS----AHNFP---K----SR--ETRAPKVAELALYRDRLPEKLRYLADAPQ-HDPE
TOP1_CAMJE GTFLE----CLK----------CKIKKEMKD-----------------------------
TOP1_HELPY GSFYG----CNNYP---K----CNFLSNHKPINKRCEKCHYLMSERIYRKKKAHE-CIKC
TOP1_HELPJ GSFYG----CNNYP---K----CNFLSNHKPINKRCEKCHYLMSERIYRKKKAHE-CIQC
TOP1_TREPA GTYTA----CVNPE--------CRYVSPTRKNLSLGKEAVLDGSHRGAQDKGAVQ-HYE-
TOP1_LACLA GKQVV----CSNDE--------CDYQEEKQK-----------------------------
TOP1_STAS1 SQVV-----CSN----------CDYKEEEQK-----------------------------
TOP1_STAAB TQVI-----CSN----------CDYKEAAQK-----------------------------
TOP1_STAA8 TQVI-----CSN----------CDYKEAAQK-----------------------------
TOP1_STAAU TQVI-----CSN----------CDYKEAAQK-----------------------------
TOP1_STAAM TQVI-----CSN----------CDYKEAAQK-----------------------------
TOP1_STAHJ SQVI-----CSN----------CDYKEEVQK-----------------------------
TOP1_STAES SQVV-----CSN----------CDYEEEVQK-----------------------------
TOP1_BACSU GIQVQ----CVE----------CDYKEEPQK-----------------------------
TOP1_HALH5 QVQVQ----CSS----------CDYKEEAN------------------------------
A5CVH7_VESOH GPYIWNGKKKGKGQ---KNITIKKVFGDKPIANLTLEECKKAISGKLKLKKKIVK-KEVT
Q28MI5_JANSC GPYVKWDKVNATIP---E---------AIDPEAITMDQAVQLIEERAAKSGKKKP-AAKK
TOP1_XYLFT GPYISDGKLNGKIP------------KDREPASLTLEEAQQLLINTGKPARKNFSTKKTA
TOP1_XYLFA GPYISDGKLNGKIP---K---------DREPASLTLEEAQQLLIDTGKPARKNFSTKKTA
TOP1_RICTY GPYIKYMCKFISVP---K---------KYDFLNLNLDDAIKLIE----------------
TOP1_RICPR GPYIKYMCKFISVP---K---------KYDFLNLSLNDAMKLIQ----------------
TOP1_RICBR GPYIKYMGKFISIP---K---------KYDFLNLSLDDAMKLIEEKLNAIAAKQP-NPLN
TOP1_RICFE GPYIKYMGKFISIP---K---------KYDFLNLSLDDAMKLIE----------------
TOP1_RICCN GPYIKYMGQFISVQ---K---------KYDFLNLSLDDAMKLIE----------------
B7J7I8_ACIF2 GAASGPARKNTG----------SKASSTKRPTKGTRTKARSSIMD---------------
Q7WXW8_PSEAI ------------------------------------------------------------
C6XEP4_METGS ------------------------------------------------------------
B1M9R9_METRJ GFWWG----CSGYR---E----GCKTIMDDDKGKPVPRAAKGATRSSNSPAKAKA-KPAA
TOP1P_XYLFA ----------------------CKATYEDKKGKPNFEKAK--------------------
C8W7T0_LANP1 GKRFIR---CTNYE---E----CETSYPLPARGKLEKTDEVCPDCGAPMVVVTTQ-RGPW
E1RJ15_METP4 AGFVTPEDFCYIHPAYLSAKTGLNIDTVYKHAAIVCEATGVRLPEKVSKKELESGRIELL
C7P1M5_HALMD SRLVG----CTRYP---D----CEYSLPLPRNGDIVVGEDRCAEHDLPEISIVDD-EDDD
TOP1_THEAC KRFLG----CSNYP---K----CTVTYPLPQMGRITKTGEVCPYCGAPILALSRN-GRKW
TOP1_ARCFU ----------------------CNYLNWKKENS---------------------------
B5IE55_ACIB4 KRFIG----CSNYP---K----CDVTYSLPQRGKIIPTGEVCPYCGAPLLILRKKGKKDW
B1L3G6_KORCO GVYLK-----------------CENCGSTNFFRVRKH-----------------------
TOP1_AERPE KALL--------------------------------------------------------
A3DP02_STAMF GKWI------------------VEVIQNFEKIKYSPSE----------------------
B8D5I1_DESA1 ------------------------------------------------------------
K0IBM4_NITGG ------------------------------------------------------------
TOP1_METTH GEFVG----CKGFP---K----CRFTCSVDEVPEG-------------------------
F6D5C7_METPW GEFIG----CSGFP---K----CRFTKSIDDDGGKTAAKTTGAPKKTVAKKAATK-KSAT
TOP1_METJA GKFVG----CSNYP---K----CRYTEKLKLNEKEEK-----------------------
TOP1_PYRAB ------------------------------------------------------------
TOP1_PYRHO ----------------------INCKDWKAKSH---------------------------
Q6F0G3_MESFL ------------------------------------------------------------
F0V2L5_MYCS3 ------------------------------------------------------------
Q9PPP9_UREPA ------------------------------------------------------------
TOP1_MYCGA ------------------------------------------------------------
TOP1_MYCPN ------------------------------------------------------------
TOP1_MYCGE ------------------------------------------------------------
Q3M6J7_TRIV2 ------------------------------------------------------------
Q4AA55_MESHJ ------------------------------------------------------------
B3PMD8_META1 ------------------------------------------------------------
TOP1P_MIMIV TIRKPSQTKYSQTKSTKSTKSTKSTNKKFVGKSAKKTTKKTTKK----------------
Q8F5G0_LEPIN ------------------------------------------------------------
TOP1_BORBU SKNKIGNKIYIYKKNDKFYAKIKRKKIDLPDNINLEEINEKYVFSLL-------------
H8H3H1_DEIGI TSGTSRRKA---------------------------------------------------
B1VAJ5_PHYAS ------------------------------------------------------------
TOP1_FERIS ------------------------------------------------------------
TOP1_THEMA ------------------------------------------------------------
B2V7T0_SULSY ------------------------------------------------------------
TOP1_AQUAE ------------------------------------------------------------
D3SM80_THEAH ------------------------------------------------------------
G8QVT8_SPHPG ------------------------------------------------------------
TOP1_SYNE7 GTPKSGETKARTTKTTKKTTTRRTTSR---------------------------------
TOP1_SYNY3 SKKASATGTAKKTTTKRTTRKKAASPDQSSEAG---------------------------
TOP1_STRCO AKKAAATKKTAAAKTTAAKKTAAKSTAKKTTAKTAAKKATASKTSED-------------
TOP1_MYCTU KRD---------------------------------------------------------
TOP1_MYCLE LAPARGISQSPR------------------------------------------------
I0II60_PHYMF TADGRVLHDEDNYVPQPL--------EAAG------------------------------
J9Z7K0_LEPFM --------PYRVRTGKKS--------VDLVCPNEACSHAKTGG-----------------
TOP1_BUCAI GNKTIV--CFDKKKKTHY--------IASKKDGKFTGWSAVFIDQKWCVINK--------
TOP1_BUCAP GNKTIV--CFNKLNKQQY--------IASKKEGKFTGWAAFFIDRKWCIVNK--------
TOP1_PSEAE GRPAVI--RFSRKTKEQY--------VQSEVDGKPTGWRAFYDGGKWKVEDKR-------
TOP1_VIBCH GLPAVV--RFSRKEKEHY--------VRTETEGKPSGWMAVYQEGKWLVTDKRKNAK---
TOP1_ECOLI GNKTMV--RFSRKTKQQY--------VSSEKDGKATGWSAFYVDGKWV--EGKK------
TOP1_SALTY GNKTVV--RFSRKTKQQY--------VAAEKDGKATGWSAFFVDGKWV--EGKK------
TOP1_HAEIN ENEAIV--RFSRKEKKQY--------VTSEKEGKATKWIVDFTNGKWV--ERKK------
TOP1_PASMU GNDAIV--RFSRKEKRQY--------VTSEKNGKATKWIVDYLGNQWV--ERKK------
TOP1_CAMJE ------------------------------------------------------------
TOP1_HELPY KERVFLEEDNG-------------------------------------------------
TOP1_HELPJ KERVFLEEDNG-------------------------------------------------
TOP1_TREPA ------------------------------------------------------------
TOP1_LACLA ------------------------------------------------------------
TOP1_STAS1 ------------------------------------------------------------
TOP1_STAAB ------------------------------------------------------------
TOP1_STAA8 ------------------------------------------------------------
TOP1_STAAU ------------------------------------------------------------
TOP1_STAAM ------------------------------------------------------------
TOP1_STAHJ ------------------------------------------------------------
TOP1_STAES ------------------------------------------------------------
TOP1_BACSU ------------------------------------------------------------
TOP1_HALH5 ------------------------------------------------------------
A5CVH7_VESOH KNS---------------------------------------------------------
Q28MI5_JANSC KTTAKKPAAKKKPAAKKTAKSAD-------------------------------------
TOP1_XYLFT TKNETRKQTTKKRTTDAKATKKVSDKPVKKQIKKRIAPNITQ------------------
TOP1_XYLFA TKNETRKQTTKKRTTDAKATKKVSDKPVKKQIKKRIAPNITE------------------
TOP1_RICTY --------NNKAKLEKKHRSMV--------------------------------------
TOP1_RICPR --------NNKAKLEKKYG-----------------------------------------
TOP1_RICBR MDEVTNLVDKKIKVKKTKK-----------------------------------------
TOP1_RICFE --------DNKAKLEKKQA-----------------------------------------
TOP1_RICCN --------ENKAKLEKKQA-----------------------------------------
B7J7I8_ACIF2 ------------------------------------------------------------
Q7WXW8_PSEAI ------------------------------------------------------------
C6XEP4_METGS ------------------------------------------------------------
B1M9R9_METRJ KPKMRR------------------------------------------------------
TOP1P_XYLFA ------------------------------------------------------------
C8W7T0_LANP1 KLCPNYDCPGKEKKTAPRRGARKSTKSTKSTKAAKK------------------------
E1RJ15_METP4 SIEGLGEAMLEKLYMAGIVSRKKLCSADPEQISKLTGIPSEKITYFQEECK---------
C7P1M5_HALMD DPWELGCPICNYAEYQARNAIDDLEDLNGIGGATAEKLAAVGIDEPADLRAVEPDEIAAN
TOP1_THEAC KFCPNMQCEYNKKRKPEAAVEKSVRKKGRNASKS--------------------------
TOP1_ARCFU ------------------------------------------------------------
B5IE55_ACIB4 KFCPNIKCEYNRRNKDEK------------------------------------------
B1L3G6_KORCO ------------------------------------------------------------
TOP1_AERPE ------------------------------------------------------------
A3DP02_STAMF ------------------------------------------------------------
B8D5I1_DESA1 ------------------------------------------------------------
K0IBM4_NITGG ------------------------------------------------------------
TOP1_METTH ------------------------------------------------------------
F6D5C7_METPW KKSATKKSATKKSATKKSATKKSATKKSATKKSATKKSATKKNAKKTK------------
TOP1_METJA ------------------------------------------------------------
TOP1_PYRAB ------------------------------------------------------------
TOP1_PYRHO ------------------------------------------------------------
Q6F0G3_MESFL ------------------
F0V2L5_MYCS3 ------------------
Q9PPP9_UREPA ------------------
TOP1_MYCGA ------------------
TOP1_MYCPN ------------------
TOP1_MYCGE ------------------
Q3M6J7_TRIV2 ------------------
Q4AA55_MESHJ ------------------
B3PMD8_META1 ------------------
TOP1P_MIMIV ------------------
Q8F5G0_LEPIN ------------------
TOP1_BORBU ------------------
H8H3H1_DEIGI ------------------
B1VAJ5_PHYAS ------------------
TOP1_FERIS ------------------
TOP1_THEMA ------------------
B2V7T0_SULSY ------------------
TOP1_AQUAE ------------------
D3SM80_THEAH ------------------
G8QVT8_SPHPG ------------------
TOP1_SYNE7 ------------------
TOP1_SYNY3 ------------------
TOP1_STRCO ------------------
TOP1_MYCTU ------------------
TOP1_MYCLE ------------------
I0II60_PHYMF ------------------
J9Z7K0_LEPFM ------------------
TOP1_BUCAI ------------------
TOP1_BUCAP ------------------
TOP1_PSEAE ------------------
TOP1_VIBCH ------------------
TOP1_ECOLI ------------------
TOP1_SALTY ------------------
TOP1_HAEIN ------------------
TOP1_PASMU ------------------
TOP1_CAMJE ------------------
TOP1_HELPY ------------------
TOP1_HELPJ ------------------
TOP1_TREPA ------------------
TOP1_LACLA ------------------
TOP1_STAS1 ------------------
TOP1_STAAB ------------------
TOP1_STAA8 ------------------
TOP1_STAAU ------------------
TOP1_STAAM ------------------
TOP1_STAHJ ------------------
TOP1_STAES ------------------
TOP1_BACSU ------------------
TOP1_HALH5 ------------------
A5CVH7_VESOH ------------------
Q28MI5_JANSC ------------------
TOP1_XYLFT ------------------
TOP1_XYLFA ------------------
TOP1_RICTY ------------------
TOP1_RICPR ------------------
TOP1_RICBR ------------------
TOP1_RICFE ------------------
TOP1_RICCN ------------------
B7J7I8_ACIF2 ------------------
Q7WXW8_PSEAI ------------------
C6XEP4_METGS ------------------
B1M9R9_METRJ ------------------
TOP1P_XYLFA ------------------
C8W7T0_LANP1 ------------------
E1RJ15_METP4 ------------------
C7P1M5_HALMD VQGVSASQIEDWQAELAD
TOP1_THEAC ------------------
TOP1_ARCFU ------------------
B5IE55_ACIB4 ------------------
B1L3G6_KORCO ------------------
TOP1_AERPE ------------------
A3DP02_STAMF ------------------
B8D5I1_DESA1 ------------------
K0IBM4_NITGG ------------------
TOP1_METTH ------------------
F6D5C7_METPW ------------------
TOP1_METJA ------------------
TOP1_PYRAB ------------------
TOP1_PYRHO ------------------