CLUSTAL format seed alignment for MF_01407
_____________________________________________________________________________
Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
CDC6C_HALMA ------------------------------------------------------------
CDC66_HALSA ------------------------------------------------------------
CDC62_METAC ------------------------------------------------------------
CDC62_METMA ------------------------------------------------------------
Q2FR23_METHJ ------------------------------------------------------------
CDC62_METTH -----------------------------------------------------------M
CDC61_SACS2 -----------------------------------------------------MSDIID-
CDC61_SULTO -----------------------------------------------------MSKIID-
CDC61_AERPE ---------------------------------------------------------ME-
CDC6D_HALMA MTDKSNNPAPASDPSTTETSNDADGSDGQLDAETDPGTSTGPSDLDDVILDNLDAGSDDP
CDC67_HALSA MTD---------DRSTDERR-------------------TADRDFEVDLDDVLDDEDDD-
CDC61_METAC ---------------------------------------------------MIKAQSLD-
CDC61_METMA ---------------------------------------------------MIKAQSLD-
CDC6_PYRAB ------------------------------------------------MSEGE-QLHLD-
CDC6_PYRHO ------------------------------------------------MNEGE-QLHLD-
CDC6_PYRFU ------------------------------------------------MNEGEHQIKLD-
CDC61_ARCFU ------------------------------------------------------------
CDC62_THEAC ---------------------------------------------------------MD-
CDC6_THEVO ---------------------------------------------------------MD-
CDC6_PICTO ---------------------------------------------------------MD-
Q74MI0_NANEQ ------------------------------------------------------------
CDC63_SACS2 ------------------------------------------------------------
CDC63_SULTO ------------------------------------------------------------
CDC6Z_METTF ------------------------------------------------------------
CDC6V_METTF ------------------------------------------------------------
CDC61_METTH ------------------------------------------------------------
CDC6O_HALMA ------------------------------------------------------------
CDC6A_HALSA ------------------------------------------------------------
CDC6G_HALMA ------------------------------------------------------------
CDC6K_HALMA ------------------------------------------------------------
CDC6B_HALMA ------------------------------------------------------------
CDC68_HALSA ------------------------------------------------------------
CDC6A_HALMA ------------------------------------------------------------
CDC6H_HALMA ------------------------------------------------------------
CDC6Q_HALMA ---------------------------------------------------MDS--DDES
CDC6I_HALMA ---------------------------------------------------MEQSEDGDL
CDC64_HALSA ---------------------------------------------------MTP------
CDC6M_HALMA --------------------------------------------------MPNNESTQTT
CDC6N_HALMA ------------------------------------------------------------
CDC65_HALSA ------------------------------------------------------------
CDC62_SACS2 ------------------------------------------------------------
CDC62_SULTO ----------------------------------------------------------MK
CDC62_ARCFU -------------------------------------------------------MQVKR
Q8ZYK1_PYRAE ------------------------------------------------------------
D3SXD8_NATMM --------------------------------------------------------MENP
A1RWU5_THEPD ------------------------------------------------------------
B1L5M7_KORCO ------------------------------------------------------------
A9A2Q2_NITMS -------------------------------------------------------MEHYV
K0IKH7_NITGG ------------------------------------------------------------
K0IN17_NITGG -----------------------------------------------------------M
Q18F92_HALWD ------------------------------------------------------------
CDC6C_HALMA --MSDDPEDRMLGWDESVFRDEH-VFEIDWLP--ETFKHRDTQMETLKYALRPAVRG-SR
CDC66_HALSA --MDEDPEEGLLGWGETVFRDEH-VFEIDYVP--EVFRHRESQLQTLQYALRPAVRG-SR
CDC62_METAC -----MTGNDILLWDETLFKDLS-VLEPDYLP--EYFPHRDSQLNALRFALRPSLRG-MR
CDC62_METMA -----MTGNDILLWDETLFKDLS-VLEPDYLP--EYFPHRDSQLNALRFALKPALRG-MR
Q2FR23_METHJ -----MTLKNMLMWDETLFRDPD-VFEIDYIP--DQFNYRESQMRELAFLLRPGIKG-SR
CDC62_METTH KGDKRRDIRDILLHDETLFRNMN-AFDPDYVP--ENYRYRESQMEALAVCIRPALRN-GR
CDC61_SACS2 ------EVISSFKTSS-IFINRE-YLLPDYIP--DELPHREDQIRKIASILAPLYRE-EK
CDC61_SULTO ------EILSSLSRSR-IFRNRE-LLLPDYVP--EELPHREEQIKRLVEILSPLMRG-EK
CDC61_AERPE ------EVFTAALESK-IFRKRW-VLLPDYVP--DVLPHREAELRRLAEVLAPALRG-EK
CDC6D_HALMA SDEASRGLFDDLLEGEPIFENKE-VLRPSYTP--HKLPHREEQINNMATILVTALRG-DT
CDC67_HALSA -----EGLFDDLLSGEPIFENKE-VLRPSYTP--HELPHRNDQINNMATILVAALRG-ET
CDC61_METAC ------GLFEKLLDGKSIFKNKE-VLRPSYTP--DLLLHRNEQINSLATILVSALRG-ET
CDC61_METMA ------GLFEKLLDGKSIFKNKE-VLRPSYTP--DLLLHRNDQINSLATILVSALRG-ET
CDC6_PYRAB ------KLFERLLKARKIFKNKE-VLRHSYTP--KDLPHRHEQIEALAQILVPVLKG-ET
CDC6_PYRHO ------QLFEKLLKARKIFKNKE-VLRHSYTP--KDLPHRHEQIETLAQILVPVLKG-ET
CDC6_PYRFU ------ELFEKLLRARKIFKNKD-VLRHSYTP--KDLPHRHEQIETLAQILVPVLRG-ET
CDC61_ARCFU -----MNIFDNILSSATIFKNRD-VLRHSYTP--EKLPHREEQINQLALLLSPMLRG-GT
CDC62_THEAC -----NPFARFAGTR-TIQANLS-LLEENYVP--DSFPHRENQINEMVTILSSIMRG-SR
CDC6_THEVO -----NPFSKFTNSR-TIQADLS-LLEENYIP--DSFPHREKQINDMVTILSSIMRN-SR
CDC6_PICTO -----NPFIKYSRSDDYIIGNLK-TLSSSYIP--DNLPHREQQIELMARSLSSIMHG-GI
Q74MI0_NANEQ ---------------MPIFKNRF-VFSEAYVP--SKILHRDDEISLIYTAISPIKQG-EK
CDC63_SACS2 --MHVIRETLKGGKGEVIKNPKV-FIDPLSVF--KEIPFREDILRDAAIAIRYFVKN-EV
CDC63_SULTO ---MSIRDTLKGGKGEVIKDPRV-FIDPLTVF--KDIPFREDILKEVAVAVRYFVKS-DV
CDC6Z_METTF ----------MFEKRPKLFKNRD-VLSPLFVP--DTLQDRKEEVGAISQYLGYILDG-AT
CDC6V_METTF ----------MFEKRPRLFKNRD-VLSPLFVP--DTLQDRKEEVGAISQYLGYILDG-AT
CDC61_METTH -----MNIFDEIGDKESVFKDKK-YLDHRFLP--DRLPHREEQIRSIAKYWVEALNG-VT
CDC6O_HALMA --------MRRFERKQNIFRNKD-ALGESYQP--ERIEERDEEIEEYMNALQPVIDG-WE
CDC6A_HALSA -----MLSMPSFERKQNIFANKD-ALGESYQP--NKIEERDDEIEKYMDALQPVIDG-WE
CDC6G_HALMA --------MATFTRDTEIFRNED-MLREDYQP--DSITAREDEISTYMAALQPIVNG-AQ
CDC6K_HALMA --------MGMFERDTEIYLDRD-ALREDYQP--ENLVGRDTELNRYRAALQPVING-EQ
CDC6B_HALMA -------MGPRFQPDDTLYKRRN-TLKVEYVP--DDIVGRDNEIEEYEAALQPIING-EY
CDC68_HALSA -------MKTPFRDRVELFANKD-VLKDHYEP--EEIRERDEEIDQYANALQDVVDG-WE
CDC6A_HALMA ------MGLEPFSPDSTIFRDES-VLRDGYQP--DRLIERDTELEQYQSALKPVING-AP
CDC6H_HALMA ---MVDVNENPFDGTDSIFERKQPLKKDTFTP--DTIFHRDEEIEFYINALQDVIVG-HD
CDC6Q_HALMA EAVHSVFNTVSQEG-GKIFEQRE-ILQIDYVPSENRIVGRDEQIEKVAGEIGPIVVG-QP
CDC6I_HALMA DAGDELFEEVDGDGKGEIFANRE-LLNIDHVPDENRIVGRDEHITELANEIGPAVTG-SP
CDC64_HALSA DSSPSSVDDPLFESGHRIFANKD-LLKIGHVPEADRIVGRDEEISKLAKRLNGAVHG-YS
CDC6M_HALMA VDEILNVDEDNDEDESNIFEKPW-LLEIDNVPDANRIVGRDDHITFLAKNLRKMRTN-SV
CDC6N_HALMA --------MIEQADEESVFRNRN-LVEPDTIIDRDRIVGRDDQLRTVVSNLRKVLNE-NR
CDC65_HALSA --------MLHDDGDASVFVNRD-LVEPDTIIDEERIVGRDEQLESVVSFLKPTLQG-NR
CDC62_SACS2 -MVSAKDILSDSLRSSVLIIKHKDKLSPDYVP--ENLPHREEKIKELGFIFKDLLAG-DA
CDC62_SULTO VLDELRDLVEDAIKGSTVFEKSK-VLTPDYIP--KNLPHREKQIKELSINFREILSN-PG
CDC62_ARCFU IIHINVSFTLMLSWDETLFKNPE-VFDPDYIP--DELLFRDGQIRQLVSCIKPAMLN-SS
Q8ZYK1_PYRAE ----------------MAIVVDDSVFSPSYVP--KRLPHREQQLQQLDILLGNWLRN-PG
D3SXD8_NATMM FKRSSVPTSSPRAESDQIFETKE-PFSKDFCP--DKVFGREDEIDRLSILLSDVVQE-FG
A1RWU5_THEPD ----MSFSYDGYARPRRIILDER-KLSSEYVP--LKLPHRAEQIAETLRVMQDVIRG-QK
B1L5M7_KORCO -------------MTIPIVRDPR-FFSDSYTP--SKLPHREKEVEILYNTLSSGYEL-NE
A9A2Q2_NITMS DKKALEKIVGDVRAQNSIFSDKS-FLDNLSVT--NSIIGRESESKKLVKFLLSYEKG-LV
K0IKH7_NITGG ---MTNNIVQDILQKHTVFKDES-VLDVEYTP--DSLMHRGRELGSLALFFRPLLET-PG
K0IN17_NITGG TDYPYPIIAGEEMSESAIFHDRS-KLSPRYVP--EELPHRQAQIEQIIHVFSDAAKDPDR
Q18F92_HALWD ---------------MSLVDNQR-PLQPEYVP--GSITDRESERKALKQALNSIHLP---
*
CDC6C_HALMA PLN--VIARGPPGTGKTTAVQILFDELTAQ-TDVKT------------VRVNCQMDS-TR
CDC66_HALSA PLN--VVARGPPGTGKTTAVQKLFGELSGQ-PGVQT------------VRVNCQVDS-TR
CDC62_METAC PLN--CLLVGPPGTGKTSAVMKVFREVEVHAPGVVA------------VKVNCQIDS-TR
CDC62_METMA PLN--CLLVGPPGTGKTSAIMKTFREVEAHAPNVVT------------VKVNCQIDS-TR
Q2FR23_METHJ PLN--ATIKGTPGTGKTTSIKKIFADISEIKSKMIP------------VHINCQVEN-TR
CDC62_METTH PVN--AVILGSCATGKTTAIKKIFEMVESTSEGVVC------------CYINCQLHT-TR
CDC61_SACS2 PNN--IFIYGLTGTGKTAVVKFVLSKLHKKFLGK-----------FKHVYINTRQID-TP
CDC61_SULTO PNN--IFIYGLTGTGKTAVTKFVVKKLHEKISNS-----------FIYVYINTRQTD-TP
CDC61_AERPE PSN--ALLYGLTGTGKTAVARLVLRRLEARASSLG--------VLVKPIYVNARHRE-TP
CDC6D_HALMA PSN--ILIYGKTGTGKTASAKFVSEELETTSQKYE--------VPCEVEYINCEVTD-TQ
CDC67_HALSA PSN--ILIYGKTGTGKTASAKFVSQELEKTSKKYD--------VPCEVEYINCEVTD-TQ
CDC61_METAC PSN--VLIYGKTGTGKTAVTRYVGKELERVSEDKS--------LFCSVVYINCEVID-TQ
CDC61_METMA PSN--VLIYGKTGTGKTAVTRYVGKELERVSEDKS--------IFCSVVYINCEVID-TQ
CDC6_PYRAB PSN--IFVYGKTGTGKTVTVKFVTEELKKVSQKYN--------IPVEVIYINCEIVD-TH
CDC6_PYRHO PSN--IFVYGKTGTGKTVTVKFVTEELKKVSHKYN--------IPVDVIYINCEIVD-TH
CDC6_PYRFU PSN--IFVYGKTGTGKTVTVKFVTEELKRISEKYN--------IPVDVIYINCEIVD-TH
CDC61_ARCFU PSN--IFIYGKTGTGKTATVLFVARQLEEASRKAK--------LNVAVHYINCEIVD-TA
CDC62_THEAC PSN--IIVYGKTGTGKTSTTKYVTKMLVEAASN------------VSVVYVNCEIYD-SP
CDC6_THEVO PSN--IIVYGKTGTGKTSTTKYVTRMLQEATSN------------VEVIYVNCEIYD-SP
CDC6_PICTO ASN--ILLYGQSGSGKTSSAINVTNMLRSAAGDR-----------VSIHYINCEIYD-SH
Q74MI0_NANEQ PLN--IFIYGQTGTGKTLVTKYVLSKIG------------------DYIYINCKFAG-IT
CDC63_SACS2 KFS--NLFLGLTGTGKTFVSKYIFNEIEEVKKEDEEY------KDVKQAYVNCREVG-GT
CDC63_SULTO KFS--TLFLGLTGTGKTFVARYMLNEIEEVKQEDSDY------SKVKQAYVNCREVG-GT
CDC6Z_METTF PPH--LLIVGPPGSGKTVTTKYVINELEKHTSDA--------------VIEYIVADG-TA
CDC6V_METTF PPH--LLIVGPPGSGKTVTTKYVINELEKHTSDA--------------VIEYIVADG-TA
CDC61_METTH PPD--ITIYGKTGTGKTAVAKFAMKQLKEASKDCDVNIRTEYIRCTDYTTEYQVIAR-LC
CDC6O_HALMA PNN--IFLYGNTGVGKTAVTDYLLDRLQDDVAAYDDIDLSI-------ISLNCKTLN-SS
CDC6A_HALSA PNN--IFVYGNTGVGKTAVTDHLLDQLQTDVEAYDDVTLSV-------IYLNCKTLS-SS
CDC6G_HALMA PRN--IFLYGKTGVGKTAVSRYLLKQLQRDTDQYDDVDLSL-------CWLNCTNLS-SS
CDC6K_HALMA PNN--IFLYGKTGVGKTAGTRYLIDHLEEDAAKYEDIDLTV-------KMLNCDGLS-SS
CDC6B_HALMA PDN--IFIYGKTGVGKTAVTNFLLNELRESADHFE-VDLTV-------ISLNCDGLS-TS
CDC68_HALSA PDN--VFVYGKTGVGKTAVTRYMMDALEYEADDRDGVDSVTS------VEVNCHHHP-SS
CDC6A_HALMA PKN--LFLYGQTGVGKTLSSRMVVERLIEDQQNIDGVDVQV-------IELNCKSLN-SS
CDC6H_HALMA PNN--VFVYGPTGVGKTAVTKWVRDKLEEKA-EAEDIPLTVV------GPINCRNYR-SA
CDC6Q_HALMA PNS--IIIYGKTGCGKSLVAKHVSKIAREEAENRGVKLATG--------YVNCQQAK-GN
CDC6I_HALMA PNS--VILYGKTGSGKSLVANHVMERARREAQRRDRRLATV--------TVDCAQSR-GE
CDC64_HALSA PEN--VMIYGKTGTGKSLVSKHVCQRAQNAAQD-GVEIGTA--------YIDCAEDN-TE
CDC6M_HALMA PDN--VLEWGETGTGKTLVARHVCERLEAATEGTDSPIVTA--------YINPDPIS-TY
CDC6N_HALMA PPN--LLLYGPAGTGKSLIFDAVARQIRDISKNRGYEFGTL--------RINCQNLR-SL
CDC65_HALSA PPN--MLLYGPAGTGKSLIIGAVTQQIIELCHSKGERFGVV--------QVNCQPIN-TL
CDC62_SACS2 KDSERVVILGRTGTGKTATVRLFGKNFEDIAEREYGVKVKY-------VHINCYRHR-TL
CDC62_SULTO STSVRVVISGKTGTGKTVTTKKFGELFSEIAK-EKGLRVVY-------THINCHRQR-TL
CDC62_ARCFU PIN--AFCLGPPSTGKTSTIRYVLREAERETGLLYS-------------YIRIPRFK-EP
Q8ZYK1_PYRAE HHYPRATLLGRPGTGKTVTLRKLWELYKDKTTARF-------------VYINGFIYR-NF
D3SXD8_NATMM APN--ILIEGQEGFGKRTVTTYVLDALQEECPTQITI-----------LDVDCKEHN-SI
A1RWU5_THEPD DVLRTIIYAGQAGTGKTAVARTIGREVKDKAAKGKIPPILV-------SYVNAQEYR-TK
B1L5M7_KORCO GLA---LLKGEPGIGKTSVAKLSASKLSNLGIGTV--------------HINCRTYR-SP
A9A2Q2_NITMS VPL--VSIYGRSGSGKSTIVQFVCQNLDVDF-----------------CYVNLRKAK-TV
K0IKH7_NITGG KASPVALIYSRSGTGKTSITKTFGGIAADMLKSKG--------IDLKYVHINCKFVT-NM
K0IN17_NITGG FPLTILQVVGVAGIGKTSTILRSSKIIEEQFVKSRLVLKTA--------YINLKLQGGNK
Q18F92_HALWD ----NILLHGPRGTGKTLLTRQLITQLEDDIQHH---------------YIDCIHHN-TE
. . **
CDC6C_HALMA YAVFSRLFAEIFD-----------------------------------------------
CDC66_HALSA YAVFSRVFEEIFD-----------------------------------------------
CDC62_METAC FAVISRIYRQLFG-----------------------------------------------
CDC62_METMA FAVMSRIYRQLFG-----------------------------------------------
Q2FR23_METHJ FMILSQIYRQIAG-----------------------------------------------
CDC62_METTH FGIFSQIYSKIFG-----------------------------------------------
CDC61_SACS2 YRVLADLLESLD------------------------------------------------
CDC61_SULTO YRILADLLENLG------------------------------------------------
CDC61_AERPE YRVASAIAEAVG------------------------------------------------
CDC6D_HALMA YRVLAQLANKFIDKNAQLIDDRIAELEELQSQARENTAALEETA----------------
CDC67_HALSA YRVLAQLANTFIDQNRAFVDARIADLSDLRAQADDDPNALEIGGSPGDDRTGNESSEGSD
CDC61_METAC YRLLANLARHFE------------------------------------------------
CDC61_METMA YRLLANLARHFE------------------------------------------------
CDC6_PYRAB YRVLANIVNHFKDETG--------------------------------------------
CDC6_PYRHO YRVLANIVNHFKHETG--------------------------------------------
CDC6_PYRFU YRVLANIVNYFKDETG--------------------------------------------
CDC61_ARCFU YRVLASLARKFG------------------------------------------------
CDC62_THEAC YSILVAIAN-SAGE----------------------------------------------
CDC6_THEVO YSILVYVAN-FAGG----------------------------------------------
CDC6_PICTO YSIMVHMVNSFIGE----------------------------------------------
Q74MI0_NANEQ KRIESFIRE---------------------------------------------------
CDC63_SACS2 PQAVLSSLAGKLTG----------------------------------------------
CDC63_SULTO PQAVLSALTERLTT----------------------------------------------
CDC6Z_METTF YQVATSI-----------------------------------------------------
CDC6V_METTF YQVATSI-----------------------------------------------------
CDC61_METTH QQLGRDV-----------------------------------------------------
CDC6O_HALMA YQVAVELVNELR--PSG-------------------------------------------
CDC6A_HALSA YQVAVELVNKLR--RPG-------------------------------------------
CDC6G_HALMA YQVAVNLVNQLR--PRD-------------------------------------------
CDC6K_HALMA YQIATRLVNEFR--DET-------------------------------------------
CDC6B_HALMA YQAAISLVNNLR--GHE-------------------------------------------
CDC68_HALSA YQAAIALVNELR--GDTD------------------------------------------
CDC6A_HALMA YQVAANLINQFR--PPT-------------------------------------------
CDC6H_HALMA YALVNTLVNEFR--DPE-------------------------------------------
CDC6Q_HALMA SDALSKYGRAIN-PPESG------------------------------------------
CDC6I_HALMA ADTVQTIADKIN-RSTSG------------------------------------------
CDC64_HALSA TQAISSLAAKLNDESSTG------------------------------------------
CDC6M_HALMA TSTFRKIAEQVNAKAENP------------------------------------------
CDC6N_HALMA DEAVYALVREAAHDLNEE------------------------------------------
CDC65_HALSA DQAVYELVQTVASDVGIE------------------------------------------
CDC62_SACS2 YLISQEIANALK------------------------------------------------
CDC62_SULTO YLMLVEIANQLN------------------------------------------------
CDC62_ARCFU YKVFSKIFQDVLG-----------------------------------------------
Q8ZYK1_PYRAE TAIIGEIARSLN------------------------------------------------
D3SXD8_NATMM YQILLHLSYEFG------------------------------------------------
A1RWU5_THEPD FQVFRKIGSDCG------------------------------------------------
B1L5M7_KORCO SSALQKIIASII------------------------------------------------
A9A2Q2_NITMS FGCINLILSELGHEN---------------------------------------------
K0IKH7_NITGG HALMQQIVRSTT------------------------------------------------
K0IN17_NITGG YAIYRFLLERIA------------------------------------------------
Q18F92_HALWD HKALRKLHTSIT------------------------------------------------
CDC6C_HALMA --------------------------------YEPPSSGISFKKLFSQITDKLVEED--E
CDC66_HALSA --------------------------------YEPPSSGISFKKLFGQVAERIADDD--E
CDC62_METAC --------------------------------ISPPNSGIAFRKLFETVVNFLVSSE--K
CDC62_METMA --------------------------------ISPPNSGIAFRKLFETVVNFLVSSE--K
Q2FR23_METHJ --------------------------------HNPSAAGNSYKRVFESIADILLTED--R
CDC62_METTH --------------------------------HQPPETGVPFSRIYQTIMQHLASEK--R
CDC61_SACS2 --------------------------------VKVPFTGLSIAELYR-RLVKAVRDY-GS
CDC61_SULTO --------------------------------SKVPFTGISTAELYR-RFIKKVLEL-KP
CDC61_AERPE --------------------------------VRVPFTGLSVGEVYE-RLVKRLSRL-RG
CDC6D_HALMA -----------FGSLDDVEAEIESLEADKSEFEEVPMTGWPTDRVYS-SFFDAVDYH-ER
CDC67_HALSA VSDSFSDLRERFDSVAEIDDRIDSLEADKAEMEQVPMTGWPTDRVYA-TFFDAVDYV-ER
CDC61_METAC --------------------------------EEVPMTGWPTDQVFM-KFKEAIDAR-DQ
CDC61_METMA --------------------------------EEVPMTGWPTDQVFM-KFKEAIDSR-EQ
CDC6_PYRAB --------------------------------IEVPLVGWPTDEVYA-KLKQVIDMK-ER
CDC6_PYRHO --------------------------------IEVPLVGWPTDEVYA-KLKQVIDMR-ER
CDC6_PYRFU --------------------------------IEVPMVGWPTDEVYA-KLKQVIDMK-ER
CDC61_ARCFU --------------------------------SNVPMTGWPTDQVYE-EVKKALERR-GT
CDC62_THEAC --------------------------------EKIPELGWPIDRIYR-ETVERVEKT-GK
CDC6_THEVO --------------------------------EKIPELGWPVDRIYR-EAVDRINGT-GK
CDC6_PICTO --------------------------------EQIPNLGLPFDRIYY-ELVKRIKSR-NL
Q74MI0_NANEQ -------------------------------------FSLQLGQDFY-DLTDVIQYIRDK
CDC63_SACS2 --------------------------------FSVPKHGINLGEYID-KIKNGTRNI---
CDC63_SULTO --------------------------------DEVPKHGINLGEYIE-KIKEELNGK---
CDC6Z_METTF --------------------------------ARAPRRGLGFLNIVE-KIRERASEGK--
CDC6V_METTF --------------------------------ARAPRRGLGFLNIVE-KIRERASEGK--
CDC61_METTH --------------------------------PYRGWTKAEIVNTFR-NMFKKNAFGQDM
CDC6O_HALMA --------------------------------GEISTTGYPQQTVFK-KLYQELEAIGGT
CDC6A_HALSA --------------------------------AEISSTGYPQQSVFK-KLYQELEALGGT
CDC6G_HALMA --------------------------------DRISTTGYPQQRVFD-ILYEELDQIGGT
CDC6K_HALMA --------------------------------SQISTTGYPRATVYD-MLWTELDSCGGT
CDC6B_HALMA --------------------------------NHIAETGHPQSKVYR-LLWNELNKLSGS
CDC68_HALSA --------------------------------SDPLTTGLSTSDVLN-ALFDEIEAREGT
CDC6A_HALMA --------------------------------EQIKPTGYPSGMIYN-MLFDELEALDAT
CDC6H_HALMA --------------------------------NQLPESGYSTDSVFE-FLYEEIEAVGGN
CDC6Q_HALMA --------------------------------VKFPTRGISENEYFE-RVWSVLNEFYDA
CDC6I_HALMA --------------------------------VTVPTRGISTNEYYN-RLWQILGTEYDA
CDC64_HALSA --------------------------------ISVPHTGLSTSKYYK-LLWKTLDAQFDS
CDC6M_HALMA --------------------------------LEVPYQGLSAEHYRDQKLWPVVQREFSG
CDC6N_HALMA --------------------------------IGVARHGVSTSTKYD-RLYDLLDEGYDS
CDC65_HALSA --------------------------------PGVPETGVSTKRKYR-RLYDLINEHYDS
CDC62_SACS2 --------------------------------LPIPSRGLSAQEVFK-MIHEYLDRR-NI
CDC62_SULTO --------------------------------LQIPNRGLSSQETFK-LIYDYLEKR-NI
CDC62_ARCFU --------------------------------QQSPPSGISKTVLMD-RVWSNLDEP---
Q8ZYK1_PYRAE --------------------------------IPFPRRGLSRDEFLALLVEHLRERD--L
D3SXD8_NATMM --------------------------------ESFVKQGHPTSTLRK-IVYKKLNEF-GG
A1RWU5_THEPD --------------------------------LDIPRRGFSSQELAEYVFGFISRRE--N
B1L5M7_KORCO --------------------------------PGVPERGLSYEEMVL--MLEKIMSREGK
A9A2Q2_NITMS --------------------------------LKNAQGMNYAFGIFEKLILQKLEKSDNS
K0IKH7_NITGG ---------------------------------GADVKGLSPDLMFR-EMYRQLDAN-NK
K0IN17_NITGG --------------------------------PELPAQGLSAEEMLRYLLRYLRENK--Q
Q18F92_HALWD --------------------------------GEDTPQGFHTSKLQRKIEKQLKHVR---
CDC6C_HALMA VLVVALDDVNYLFYESEA------SDTLYSLLRAHEAHS----GAKIGVICVSSDLELDT
CDC66_HALSA VLVVALDDVNYLFYEDEA------GDTLYSLLRAHETQP----GAKVGVVVVSSDLELDV
CDC62_METAC VLIVALDDLNYLCCEGHA------NEVMYSLLRAHEQYP----GAKIGVIGIVND--ASD
CDC62_METMA VLIVALDDLNYLCCEGHA------NEVMYSLLRAHEQYP----GAKIGVIGIVND--ASD
Q2FR23_METHJ VLLVALDDANYLLFENEL------NNILYLLLRSHETYP----GTRIGVMVIISDMDVDL
CDC62_METTH ALVVALDDINHLFYSKNA------NKVLYDILRAHEVFE----GVRTGVFAVLSD--IEF
CDC61_SACS2 QVVIVLDEIDAFVKKYN-------DDILYKLSRINSEVN----KSKISFIGITND--VKF
CDC61_SULTO ILVIVLDEIDALVKKHG-------DDILYRLTRANYEMG----KSKVSIIGITND--IKF
CDC61_AERPE IYIIVLDEIDFLPKRPGG------QDLLYRITRINQELGD---RVWVSLVGITNS--LGF
CDC6D_HALMA VVVIMLDEIDKLVEKSG-------DDTLYNLSRMNSELE----NSRVSIMGISND--LKF
CDC67_HALSA VAVIMLDEIDKLVEKSG-------DDTLYNLSRMNSELD----NSRVSIIGISND--LKF
CDC61_METAC VIIIILDEIDKLIKK-G-------DDVLYNLSRINTDLR----KAKVSMIGVSND--LKF
CDC61_METMA VIIIILDEIDKLIKK-G-------DDVLYNLSRINTDLR----KAKVSMIGVSND--LKF
CDC6_PYRAB FVIIVLDEIDKLVKKSG-------DEVLYSLTRINTELK----RAKVSVIGISND--LKF
CDC6_PYRHO FVIIVLDEIDKLVKKSG-------DEVLYSLTRINTELK----RAKVSVIGISND--LKF
CDC6_PYRFU FVIIVLDEIDKLVKKSG-------DEVLYSLTRINTELK----RAKVSVIGISND--LKF
CDC61_ARCFU RVVVILDEIDKLVKK-A-------EEALYGLTRINSELE----NSSICIVGISNN--LKF
CDC62_THEAC FFIIILDEMDRLIKKNG-------GDSLYVLLKLMTDVD----SVRVSMIGITND--TTV
CDC6_THEVO FFVIVLDEMDRLIKKSG-------GDSLYVLLKLMTDVE----NVKVSMIGITND--TTL
CDC6_PICTO YTLIILDEIDRLLSKNG-------SDSLYVILKLLGDTE----G---SIIGITND--SSF
Q74MI0_NANEQ KLIIVFDEVDQLSKDLG-------DEILYTFTRAPGNIG---------IIGISNN--IFF
CDC63_SACS2 RAIIYLDEVDTLVKRRGG------DIVLYQLLRSDANIS---------VIMISND--INV
CDC63_SULTO KALVYLDEVDTLIKRRGG------DIVLYQLLRADADIS---------VIMISND--INI
CDC6Z_METTF -MIIVMDEIDKTLSRDG-------DKLLYHLSREP----------NVCIVGLSNK--LTV
CDC6V_METTF -MIIVMDEIDKTLSRDG-------DKLLYHLSREP----------NVCIVGLSNK--LTV
CDC61_METTH ILMVVLDEIDILLRNDG-------DGLLYTLTRTD----------NVSILSISNY--VEF
CDC6O_HALMA -ILIVLDEVDSIGDR---------DELLYELPRARANGN--LDSAKVGVIGISND--FKF
CDC6A_HALSA -ILIVLDEVDAIGDR---------DDLLYELPRARSQGN--LEDAKVGIIGISND--YKF
CDC6G_HALMA -ILLVLDEIDHIGSD---------DEILYEIPQARSNGY--LSEAKPGVIGISND--FGF
CDC6K_HALMA -IYIVLDEVDHIED----------DSILYQLPRARANDN--LSSAKIGIIGISND--FSF
CDC6B_HALMA -VIIVLDEIDHITD----------DTFLYQITRADNNGY--IDNIQLGVIGISND--STF
CDC68_HALSA -VLIVLDEIDNLDDD---------DMLLYQLPRAKTNGN--IEDSQVAVVGISND--YTF
CDC6A_HALMA HCLIVLDEIDAIGND---------DDILYKLPRANDNEN--VEDTLVGVIGISND--FTF
CDC6H_HALMA -VLIILDEIDNIPADAR-------NDFLYELPRAEANENTPITDAKVGLIGISND--LKF
CDC6Q_HALMA AIIVL-DEVDKLNN----------DDLLMALSRAGEDGS---VDVPIGVIAVSNK--INY
CDC6I_HALMA ALITL-DEVDRLSD----------DDILMILSRAREAGK---VDVPIGIISISNK--VNF
CDC64_HALSA VIIIL-DEIDLMND----------DSVLMKLSRAEEAGK---IDCSVGVIAISNK--IQY
CDC6M_HALMA GLVVIIDEIDKHGEV---------NEVLYTLSRTQSKDD---VDFPVITIGISND--IEF
CDC6N_HALMA VVFVL-DEIDLLLGRRSSSSEPAYSDLIYQLSRAS-IES---IDIQVSVAALTND--PEF
CDC65_HALSA VIFIL-DEIDLLVGRRAND-EPAYSKLLYQLSRASNTND---IEGQVSVAALTND--PKF
CDC62_SACS2 HLIVALDEFGHFLNTAN-------TEEIYFLVRLYDEISA--IIKRISYIFIVNE--SHS
CDC62_SULTO QLIITLDEFDYFVSTSP-------VEDIYFLVRIYDELNA--LVKRIHYIFILRE--LTS
CDC62_ARCFU -LLVVLDDINFLGKNYA-------NEILYEILKAPDEYG-----VKVGIVAAATD--VKF
Q8ZYK1_PYRAE YMFLVLDDAFNLAPDIL--------STFIRLGQEADKLG----AFRIALVIVGHN--DAV
D3SXD8_NATMM TVLIILNNIQELGPD---------DQPVAEFQEACTDGDI--SNAEVGVIGLCNR--IRL
A1RWU5_THEPD NALIILDEADILAKQKDG------NELFYVFSRVREVLPE--VQLGLGLIVIFRQ--LDE
B1L5M7_KORCO PLLIILDEIEYLREG---------ETLVYTLLRLHEGGA----TKSPTLVAVARW---DP
A9A2Q2_NITMS IFVLCLDEFDTLFYDKRGK----PSDFVYKIVVLVEKLRT--LKRHMCIVTISNK---VL
K0IKH7_NITGG YLLLTLDEVDWFIKRTG-------EDLIEQLTRYREELSR---PKRLAIIFVIRDSNIDT
K0IN17_NITGG YALIIMDEIDYLIKTSKD------TGIIYDLTRLNEFEP----DKPCNVKGVVFIARSTE
Q18F92_HALWD -HLIVLDEADFLLQNNG-------NSLLYYLSRINKPAN-------LGIIIVSAH--TAS
:: . :
CDC6C_HALMA IDAL-DTRVQSVFRPEEVYFNPYGQAEIADILGERA--------DRGFN-----------
CDC66_HALSA IEAL-DGRVQSVFRPEEAYFSAYDRAEITDILRDRV--------EVGFR-----------
CDC62_METAC LYCL-DSRVNSVFLPEEISFLRYGEAEILDILKDRV--------KYGFY-----------
CDC62_METMA LYCL-DSRVNSVFLPEEVSFPRYEEGEILDILKDRV--------RYGFY-----------
Q2FR23_METHJ SREL-DIRVTSVFSPTEVYFPPYSVTETFQILKERV--------LQGLY-----------
CDC62_METTH RYAL-DKNVDSIFIPQEIVFPPYTREEVFNILRDRV--------RVGFY-----------
CDC61_SACS2 VDLL-DPRVKSSLSEEEIIFPPYNAEELEDILTKRA--------QMAFK-----------
CDC61_SULTO VEFL-DPRVKSSLSEEEIVFPPYNAEELEDILKRRA--------TLAFY-----------
CDC61_AERPE VENL-EPRVKSSLGEVELVFPPYTAPQLRDILETRA--------EEAFN-----------
CDC6D_HALMA TDFL-DPRVKSSLGEEEIVFPPYDANQLRDILQARS--------DVAFK-----------
CDC67_HALSA TDFL-DPRVKSSLGEEEIVFPPYDANQLRDILQHRS--------DVAFK-----------
CDC61_METAC TEFL-DPRVKSSLGEEELIFPPYDAEQISDILKQRA--------KMAYN-----------
CDC61_METMA TEFL-DPRVKSSLGEEELIFPPYDAEQISDILKQRA--------KMAYN-----------
CDC6_PYRAB KEYL-DPRVLSSLSEEEVVFPPYDANQLKDILTQRA--------EEAFY-----------
CDC6_PYRHO KEYL-DPRVLSSLSEEEVVFPPYDANQLRDILMQRA--------EEAFY-----------
CDC6_PYRFU KEYL-DPRVLSSLSEEEVVFPPYDANQLRDILTQRA--------EEAFY-----------
CDC61_ARCFU KEYL-DARILSSLSEEEIVFPPYNAEQLEDILQQRA--------KLAFE-----------
CDC62_THEAC LENI-DARIKSRLNQESIVFPPYNASEIRDIISSRL--------DKVLG-----------
CDC6_THEVO LENL-DSRIKSRLNQESIVFPPYNATEIRDIIASRL--------EKVFG-----------
CDC6_PICTO INKL-DMRVRSRLNAESIIFTPYNADELRDILKFRI--------NGVIK-----------
Q74MI0_NANEQ VDRL-DPRVRSSLSELEILFKPYNALQLRDILLERA--------KEGLY-----------
CDC63_SACS2 RDYM-EPRVLSSLGP-SVIFKPYDAEQLKFILSKYA--------EYGLI-----------
CDC63_SULTO RDYM-EPRVLSSLGP-TVFFKPYDAEQLKHILSIYA--------EYGLY-----------
CDC6Z_METTF MDMIGDSGVISSFKPRRISFAPYSAPQLEEILNYRV--------EMAFN-----------
CDC6V_METTF MDMIGDSGVISSFKPRRISFAPYSAPQLEEILNYRV--------EMAFN-----------
CDC61_METTH KKFI-KPRVRSSLRDREIVFPPYGAQQLVDILEERS--------KMSFK-----------
CDC6O_HALMA RDQL-DPRVQDTLCERELQFPPYDATELKNILESRV--------EVAVT-----------
CDC6A_HALSA QEQL-DPRVQDTLCERELQFPPYDALELANILDSRT--------DIAIA-----------
CDC6G_HALMA RDNL-SPKVKDTLCEEEIHFSPYNAPELRAILEERV--------TGAMY-----------
CDC6K_HALMA RDDL-SPKVKSSLCEEEIQFPAYDAKELIQILQQRA--------DVAFH-----------
CDC6B_HALMA REQL-DAKVQSSLCETEISFPPYGTEELQKVLEQRA--------EIAFH-----------
CDC68_HALSA RNDL-SPKVQDTLCEREIKFPPYDANELVTILDDRA--------ERALS-----------
CDC6A_HALMA RDNL-SARVKDSLADEEIHFPPYDANELGNILKQRA--------GEAFHGTSAQRLDDGS
CDC6H_HALMA VDVL-EPKVKSTLGEREIKFGPYDATELRDILGYYA--------DIAFR-----------
CDC6Q_HALMA RDKM-SERTKSSFGHNEFIFEPYDADQIREILQNRT--------DAFAD-----------
CDC6I_HALMA REQM-TERVKSSLGHNEMIFDPYDGEQLRQILENRK--------DAFQE-----------
CDC64_HALSA VDNV-NERVKSSFQHKELFFKPYDANQLREIMFNRE--------DAFQD-----------
CDC6M_HALMA KGEI-ESRVQSTLQPEHRTFTPYEEDQLIAILENRR--------DAFYD-----------
CDC6N_HALMA MNNL-DARAESSFNPRDIPFSDYDANQLQEILRNRE--------DAFIQ-----------
CDC65_HALSA MENI-DGRAESSFNPRDIYFPDYDATQLRQILENRR--------DAFRQ-----------
CDC62_SACS2 IYKL-DRSIRDHIARRLIEFPPYKSMELYDILKYRV--------DEAFN-----------
CDC62_SULTO LASL-DKSIKDHVIKNVIEFPPYTSEELYDILMDRIV------NEKAFR-----------
CDC62_ARCFU PLLL-DPFVGASFHYMEIHYPSYGYAEIEGILRKRV--------EHGFY-----------
Q8ZYK1_PYRAE LNNL-DPSTRGIMGKYVIRFSPYTKDQIFDILLDRA--------KAGLA-----------
D3SXD8_NATMM PYHL-AESVKNHAQTSKVTFEPYRSPELRAILEYHA--------EIAFK-----------
A1RWU5_THEPD SLAYLDKAVVSSLSGRVVRFNPYTSQQLQDILWARIRDEGAIR-----------------
B1L5M7_KORCO PYTL--DDSIKSFMILKLTLEKYNASQLYDILDYRA--------SEALY-----------
A9A2Q2_NITMS SEFNLDDRVVSRIGTSEIYFDSYSQSDVLKIIRNRA--------KKSFL-----------
K0IKH7_NITGG MAELERSKLHRTFGARMLKLEPYTKEQLVDIIGQRV--------QMAFRT----------
K0IN17_NITGG FYSRLDPAELSTLGRVPMEFHPYSIEQVSDILESRA--------GQAFN-----------
Q18F92_HALWD LQSQIDERTYSTLQPRRIGTEPYTSEQVYQILSERA--------RQSLE-----------
* : ::
CDC6C_HALMA ----EGVVGPTVLDRVAELTEEQ------GGDLRVGIDLLRRAGMNAEMRASRSVETEDV
CDC66_HALSA ----EGAVAEPVLDAVGGRTDE-------AGDLRVGIDVLRRAGLHAESRASKTVEMEDV
CDC62_METAC ----PKVISDDVLELVVSYVEK-------TGDLRVGIDLLRRSGFNAERRGSRTISSGDV
CDC62_METMA ----PKVISDEVLKLVVSYVEK-------TGDLRVGIDLLRRSGFNAERKGRRMILFEDV
Q2FR23_METHJ ----PGVLSDKNLDLIVDHTLR-------SGDMRVGIDMIKRAGLNAEKEAMREISEEHI
CDC62_METTH ----PGVISDELLERITDHTMD-------TGDLRYGIDLLRVCGNLAEADASPVIGEEHL
CDC61_SACS2 ----PGVLPDNVIKLCAALAARE------HGDARRALDLLRVSGEIAERMKDTKVKEEYV
CDC61_SULTO ----DSVVSDDVIKLCAAIAARD------HGDARRALDLLRVAGEVAERDGAEKLTIEHV
CDC61_AERPE ----PGVLDPDVVPLCAALAARE------HGDARRALDLLRVAGEIAERRREERVRREHV
CDC6D_HALMA ----GDALTEDVIPLCAAFAAQE------HGDARRALDLLRTAGELAERDQTDNVLEDHV
CDC67_HALSA ----ADALSDDVLPLCAAFAAQE------HGDARRALDLLRTAGELAERDQAENVTEDHV
CDC61_METAC ----DGVLGEMVIPLCAAFAAQE------HGDARRALDLLRVSGEIAERENQPQVLEEHV
CDC61_METMA ----DGVLGEMVIPLCAAFAAQE------HGDARRALDLLRVSGEIAERENQPQVLEEHV
CDC6_PYRAB ----PGVLEEGVIPLCAALAARE------HGDARKALDLLRVAGEIAEREGASKVTEKHV
CDC6_PYRHO ----PGVLDDGVIPLCAALAARE------HGDARKALDLLRVAGEIAEREGASKVTEKHV
CDC6_PYRFU ----PGVLDEGVIPLCAALAARE------HGDARKALDLLRVAGEIAEREGASKVTEKHV
CDC61_ARCFU ----DGVLEDGVIQLCAAIAAQE------HGDARKALDLLRVSAEIAERERDSMVRVEHV
CDC62_THEAC ----PGVVDDTAINLCAAIGAQE------HGDARKAIDLMRIAIEIAIRENRNKITENEI
CDC6_THEVO ----PGVVDDTAINLCAAIGAQE------HGDARKAIDLMRIAIEIAIRENRLKVTEKEV
CDC6_PICTO ----NGFIEDSAINLCAAIGAQE------HGDARKAIELLRIAIEYCIRENRERVTIDDI
Q74MI0_NANEQ ----ENSYDLAAISYIAAVTARE------YGDARRAINLLRLAGEIAERKGKNKIELEDA
CDC63_SACS2 ----KGTYDDEILSYIAAISAKE------HGDARKAVNLLFRAAQLASGGG--IIRKEHV
CDC63_SULTO ----RGTYDDNILSYIAAISAKE------HGDARKAVNLLFRAAQLASGEG--FIRKDHV
CDC6Z_METTF ----DGVLEDDVVPLCAALAAQR------NGDARYALDLLSFAADIAIRQLKGVVSESDV
CDC6V_METTF ----DGVLEDDVVPLCAALAAQR------NGDARYALDLLSFAADIAIRQLKGVVSESDV
CDC61_METTH ----EGALDDDVIPLCAALAAKE------EGDARYALDLLRTAGEIADERDSDKVLGDFV
CDC6O_HALMA ----DGSTDTGVLQLCAALAARD------SGSARQALDLLRLGGEIAENREAEMIKEGHI
CDC6A_HALSA ----DDSLAEGVTQHCAALAARD------SGSARQALDLLRLAGELAENQDADAISTDHV
CDC6G_HALMA ----DDAVDDAVIALCAAIAAQD------TGSARQALDILYKSGEIARTNGEERLTEDHV
CDC6K_HALMA ----DGVLEDGVIELCAAYGAKD------AGDARQSLDLLMKTGDLARDKDTDTISEDLV
CDC6B_HALMA ----ESALEDGVIPLCAALGRQD------GGDARRAITLLRKAGDLARTENANSVTTDHV
CDC68_HALSA ----SGVLTGGVIPQCAALAARD------RGSARQAIDLLRESVNVAIEDERETVTEDDV
CDC6A_HALMA YELQSDILEGDVVPLCAAFAAQD------SGSARQALKRLYKAGDLARDEESDVITGAHV
CDC6H_HALMA ----EDVLGEDVVPLAAAFSAQE------RGDVRQGLRILEKAGEYARMEGAEGVTEAHT
CDC6Q_HALMA -----GVLDDGVIPRAAALSAKE------HGDARKAMRLLRYAGDQANKENAERVKESHL
CDC6I_HALMA -----DILMPGVIPKTAALAAQR------HGDARKAIRLLRHAGDYAKTNNIGTVKESHL
CDC64_HALSA -----GVLSEDVIPLSAAFAAQE------HGDARKAIDILRHAGEVAYEAGAELVTEEHV
CDC6M_HALMA -----GVLDDEVIPTTAELAAEE------HGDARRAVRLFRNAGEIADEEGDDIVTAEHV
CDC6N_HALMA -----DALSEDVIPLTSAFAAQS------HGDARKAIDLLRKAGDVANENGDLTVTENHV
CDC65_HALSA -----DALTDDVLPLVSAFAAQS------HGDARKAIDLFRGAGDLADEQGDQTVREDHV
CDC62_SACS2 ----DNAVDDEVLQFISNTYGYDK---GGNGNARIAIETLSLAGEIAEKEGSPVVLLDHA
CDC62_SULTO ----EGAVLEETVRFISDIYGIDK---GGSGNARLALETLELAGKIADTEGSLLVTIDHA
CDC62_ARCFU ----EGVFDDGAFRRVVELAYRA-------SDVRYGIYLLKAAGMNAESRGSRKVEERDV
Q8ZYK1_PYRAE ----EGSYSEDILQMIADITGAQTPLDTNRGDARLAIDILYRSAYAAQQNGRKHIAPEDV
D3SXD8_NATMM ----DDVLAPGVVPKCAAISAQL------TGDARTGLTLLKLAGEIAKESSDEQITEKHV
A1RWU5_THEPD ----EEAVSEEIIEMIADTVGYNPDTKSGIGDARMAIKVLYYSALRAEGEERETILPEDV
B1L5M7_KORCO ----DGSYDSNTIEKVVELSKHT-------GNARIALKILFSAARLAEERGMSLITPDLV
A9A2Q2_NITMS -----KKIDDDVLQYCADISSEE------HGDARRAIDLLRTSGEIAGTEN-EKISKKHV
K0IKH7_NITGG ----DGSVPDNIIDFIAEMACSI-------GDAYYAIQILWKAGKCADNFGMDRVIPEHV
K0IN17_NITGG ----PKAIGSDVIDKVAEITASPE----VNGDVRYALDLLLYAGNLAESQGTGRVTLDHV
Q18F92_HALWD ----PTSLHHEALTYLASATENT----------KLGLHWLRHAAQNTSQPISEETLKQTQ
.: :
CDC6C_HALMA EAAYDKS--KYVHLSRRL-RELSDSETALVEVIAAH-----------DGQQAGDIYDAFS
CDC66_HALSA DAVYEDA--KHVHLSRTL-AALSDNERALVRTVAEQ-----------EGDRAGDVYDVFN
CDC62_METAC EKAYEAS--KLLHLCRGI-SLLSDSEKQLLELIAKA-----------DDVKAGELYKSFH
CDC62_METMA EKAYEAS--KLLHLCRGI-SLLSDPEKQLLELIAKK-----------DEIKAGELYKSFH
Q2FR23_METHJ HEAYKIS--RFLHLKYSI-QALRREEKDLLRLLVDLSRKD-------EQLTSGQVYTIVK
CDC62_METTH ERALKST--GPVNLIHTV-RTLNENEREFLRILADAG----------EDMTAGALYELFR
CDC61_SACS2 YMAKEEI--ERDRVRDII-LTLPFHSKLVLMAVVSISSEE---NVVSTTGAVYETYLNIC
CDC61_SULTO NKARVEI--ERDRVYEVV-STLPFHSKLVLLAIVIGVNEK---RRTLTTGEVYDVYTKLA
CDC61_AERPE YSARAEI--ERDRVSEVV-RTLPLHAKLVLLSIMMLE-DG---GRPASTGEIYERYKELT
CDC6D_HALMA RQAQEKI--ELDRVVEVV-RTLPTQSKIVLFAIILLEKNG---VHNINTGEVFNIYKNLC
CDC67_HALSA RRAQDKI--ELDRVVEVV-RTLPTQSKLVLYAILLLEDNG---VHNVNTGEVYNIYKTLC
CDC61_METAC RRAQEKI--EIDRVVEVV-RTLPTQSKLVLYSIILLRSRGRE-GKNVTTGEMYNVYRQLC
CDC61_METMA RRAQEKI--EIDRVVEVV-RTLPTQSKLVLYSIILLRNRGRE-GKNVTTGEMYNVYRQLC
CDC6_PYRAB WRAQEKI--EQDMMEEVI-KTLPLQSKVLLYAIVLLDENG---DLPANTGEVYSVYRELC
CDC6_PYRHO WKAQEKI--EQDMMEEVI-KTLPLQSKVLLYAIVLLDENG---ELPANTGEVYSVYRDLC
CDC6_PYRFU WKAQEKI--EQDMMEEVI-KTLPLQSKVLLYAIVLLDENG---DLPANTGDVYAVYRELC
CDC61_ARCFU KKAVRKI--ETDYMIETV-RTLPVHSKILLYSMSLISENS----PKFTTGEVYCVYKKLC
CDC62_THEAC YEARERY--EMNVLREAI-STLPLHSKIVLLSAVVTQEIE---PNSVITGEIYENYRRIC
CDC6_THEVO YEARDKY--EMNVMHEAI-NTLPIHSKIVLLSAIVTQEIE---PNSVITGEIYENYRRIC
CDC6_PICTO YMARERF--EMNILKESV-KTLPIHSKMVLLSAILTQEVS---SDIAVTGEIYENYKNIC
Q74MI0_NANEQ KEAIELE--EKDKVKFVI-ESLPLQSKLVLKSIAELKDTT--------LGKAYELYYRKS
CDC63_SACS2 DKAIVDY--EQERLIEAV-KALPFHYKLALRSLIESEDVM----------SAHKMYTDLC
CDC63_SULTO DRAIIEY--EQERLIEAI-KALPFHYKLALMATMDAEDVV----------TAHKIYSDLC
CDC6Z_METTF RMATDEV--EVEFIRRSI-EQLRDNQKILLYAVMTSQGGT-------PTEIYRKYNKMAE
CDC6V_METTF RMATDEV--EVEFIRRSI-EQLRDNQKILLYAVMTSHGGT-------PTEIYRKYNKMTE
CDC61_METTH REAKDYI--EHNKITDII-LTLPSQQQRVLEAILYLTKRK-------EEITSGRLYEVYK
CDC6O_HALMA EDARSQL--EQERVEEGM-RELTTHGRLALLAVISKA---AKEETPCRTRDLYEEYRSLC
CDC6A_HALSA EAARSEL--ERERVEEGM-RELTTHGRLTLLAVVSKA---AKADTPSRTRAIYDEYASLC
CDC6G_HALMA HQAREKL--EQSQVEHGM-RELTKHGHLALVAMLQLA---FEQETPARIRDVYPLYRRIA
CDC6K_HALMA REARDVL--ERGRIQEGI-SGLTQHGHLVVYAMVTLD---QEGKTPARTRDIRPRYTNFA
CDC6B_HALMA ERAQEKL--EAQQSMDIM-RDLTEHEQLTLYALTTLA---AEGETPARSRIVYQRYKELC
CDC68_HALSA ETAVRRV--ERGRIKDSI-KDLTTHGQYVLLAVTQTA---IADDTPVRAKELYEVYADIA
CDC6A_HALMA RQADEIV--ERDKVRDEL-TRLPTQSKLTLYSLLLLE---REDETPSKRNRIYERYVMAA
CDC6H_HALMA RRATDTI--ETDELLDYFEHDLSSQQALTYLATTLAL---IEPKHEASTKRIYNLYSSIA
CDC6Q_HALMA TDARASA--EVDRLLELI-SGLPPHSKHVLLALANLTKNHPD-REWFRTVRVREIYLEVC
CDC6I_HALMA ELAQEQA--EVERLKELI-SGLPPHSKYVLYALANLTDGTTNSNDWFRTTVIYDVYEEVC
CDC64_HALSA RQAQQHA--EKDRFRELV-NGAPTQAKAALLALTELSVNSND--DAFLTSRVYDQYEHIC
CDC6M_HALMA HEADELV--EVELFMEMV-KGTPLSGKLLLFALTRLDRNNPE-KEWFRTSEIHEVYQTVA
CDC6N_HALMA REAQEDV--ETDRSLKLV-EGLTTQKKISLYATAAVAEFGKSGSTTASSRVAFPVYQFLT
CDC65_HALSA RESQDEI--DKDRSLKLI-AGLTTQKKISLYATAAVAHCSSATRNSVPSPVGFQVYQWVT
CDC62_SACS2 KKANSTINPEIQEIIDSL-SYLDLHQLILLKALIRALNKTKA--DEITMGTLEEEYISLS
CDC62_SULTO KKANSKINPELSIILDTI-RDLDLHQLLVVKAIMNLHKKEGD--DFFSMGKVEEEYNIVA
CDC62_ARCFU EVAHAGE---SLSFIAKILTALNSEERAVLRMIYSQN-----------AISTGDLYEQVC
Q8ZYK1_PYRAE RKSSKEV---LFGISEEVLIGLPLHEKLFLLAIVRSLKISHT--PYITFGDAEESYKIVC
D3SXD8_NATMM DRANSKL--DTTQFIESYVEDFSREEQLVGLIIALLDMRN---ECEIEFRHVYSHYYEYA
A1RWU5_THEPD RYVVNQGV-LPSYIDEETVTRLPLHEKLLLLAITELLLLERE-KAYVNMGEVVIQYEDVC
B1L5M7_KORCO SEAAARI--GVVGITEDSLMPLDTHDKLLLLAAARRLAMTSR--GWIKMGDLLEEYKLIC
A9A2Q2_NITMS DKAVSQLQ---KNQITTIISGGSYHFRLACAALSRLTYINDE-----GWHSTSDLFKQYQ
K0IKH7_NITGG RMAKSMT---DPKVRSEDLLSLPRDEKVVLQAVANLLRKESN--IYVNLSDITETYHVLC
K0IN17_NITGG RKVHGQV---HPSITTEEIEQLSKNHLVSLMALVRALKSKKK--PYVELKDVRLYASELA
Q18F92_HALWD KQAHHRF-------TERTLSHHTDHHRTLYRAIRNFDDYPIN------SGQIYTTYREHC
CDC6C_HALMA EQTD-----LGYTRYSEIINKLDQLDIIDADYTNVEG--------RGRSRELTLNYDADA
CDC66_HALSA DRTD-----LGYTRYTEIVNKLDELGVIDAAYEQRSG--------RGRSRTLRLTHDSEA
CDC62_METAC ELTQ-----LGYTRFYGMVNRLQTLNYVDADFTGKGK--------RGRTRIIKAKYEAED
CDC62_METMA ELTQ-----LGYTRFYGMVNRLQTLNYVDADFTGKGK--------RGRTRIIKTKYEAED
Q2FR23_METHJ KKLK-----LGYTIYYEALRKLDTLRLINLEFR--DG--------RGRTRLINLRYDPDK
CDC62_METTH ESTG-----SSYSSFNRIIEKLEFLRLIDTRLTGKGV--------RGNSRILIPRFSRED
CDC61_SACS2 KKLG--VEAVTQRRVSDIINELDMVGILTAKVVNRGR--------YGKTKEIGLAVDKNI
CDC61_SULTO KKIG--VESVTQRRVSDIINELDMLGIITARVVNRGR--------YGKTKEVNLAVNEET
CDC61_AERPE STLG--LEHVTLRRVSGIISELDMLGIVKSRVVSRGR--------YGKTREVSLDADRLA
CDC6D_HALMA EEID--ADILTQRRVTDLISELDMLGIVNAVVVSKGR--------YGRTKEISLSVPTEE
CDC67_HALSA DELD--ADVLTQRRVTDLISELDMLGIVNAVVVSKGR--------YGRTKEISLSVPVEE
CDC61_METAC HHID--VDILTQRRVTDLMSELDMLGIVNAVVVSKGR--------YGRTKEISLSVPVEN
CDC61_METMA HHID--VDILTQRRVTDLMSELDMLGIVNAVVVSKGR--------YGRTKEISLSVPVEN
CDC6_PYRAB EYLD--LEPLTQRRISDLINELDMLGIINAKVVSKGR--------YGRTKEIRLNVTPYK
CDC6_PYRHO EYLD--LEPLTQRRISDLINELDMLGIINAKVVSKGR--------YGRTKEIRLNVTPYK
CDC6_PYRFU EYID--LEPLTQRRISDLINELDMLGIINAKVVSKGR--------YGRTKEIRLNVTSYK
CDC61_ARCFU GKVG--VDPLTQRRISDLISELDMLGILNSVVISKGR--------YGRTREMKLEADEKV
CDC62_THEAC DDLG--FSPLSPRRISDLLTELADYGLLVMDDRNMGK--------YGRTRSFSVVHQAET
CDC6_THEVO EDLG--FTPLTPRRISDLLTELSDYGLIVVDERNMGK--------YGRTRGFSVVKEIET
CDC6_PICTO AEIG--LQPLSTRRISDLMSSLDDLGLIVTTTRSMGR--------YGRTKLIKVSQPV-A
Q74MI0_NANEQ LEKS--VTPITFRRFVEIVNDLETLGLVSIDFALLN---------GKRVRKVKTFISPKI
CDC63_SACS2 NKFK--QKPLSYRRFSDIISELDMFGIVKIRIINRGR--------AGGVKKYALVEDKEK
CDC63_SULTO NQYK--QKPLSYRRFSDIISELDMFGIIKVKIINKGR--------AGGIRKYIEITDKDK
CDC6Z_METTF EQFG--GNALTQRRLSQLLRELELYGLVEIEVVGRGR--------GRGVNWHVVPSSSID
CDC6V_METTF EQFG--GNALTQRRLSQLLRELELYGLVEIEVVGRGR--------GRGVNWHVVPSSSID
CDC61_METTH EIAK--GDSVSYRRIFDFINELEMLGLISTNTVSRGR--------GK--GRTNIIDLQCE
CDC6O_HALMA ESSE--TDALGQRSLHNHLSDLRMLGILSAHENRSG--------SRGNYYNYELDVPFTS
CDC6A_HALSA KSAANTDDPLKQRSVHNHLSDLHMLGILSKYENRSG--------SRGNYYSYELDVPFES
CDC6G_HALMA EGSN--VDPLVRRRMHDHLADLAMLGILGRQMKNEGR-------AGGHYYQYEFDVGLDI
CDC6K_HALMA EKAG--IDPLVPRRMRDHLGELSMLGIISAIERNEGR-------RGGTYREYSLEMDPEM
CDC6B_HALMA EFQG--REPRTARRMRSFLSDFEILNLTLSEMEHRGQ-------DGGTYRQHELNRDIAT
CDC68_HALSA AEYA--SDPLSQRSVHDHLNDLSMLGFLRQHDRNYGR-------GGGQFFEYELDVDATM
CDC6A_HALMA KRID--ADVRTDRTIHDRLSQLTLKGFLDVDEQNKGP-------KGGSYYEYEFSIRADL
CDC6H_HALMA ESSG--RRVKSERKIYEFLDQLSMQGLVRSAERNLGR-------KGGRKYIYEVTDDPTD
CDC6Q_HALMA DRSG--ADPLSAERTRQLLNELCFLEVAGSRR-GTG-------EGKGHYSQYTLLWDADI
CDC6I_HALMA KTEA--TDTLTTDTIRGLLNELAFLEITESNQEHGG-------MGKGTYKEHRLLWDPNV
CDC64_HALSA NHLD--MDILSVRRFRDILKEQAFLGVVEIEKINKG-------SAGGIHLQNRLIEDSQV
CDC6M_HALMA RDVK--VEPKGYNRALELLNKHVTTGVLESKKKEGG-------D-QGKFRSYSLQGDVES
CDC6N_HALMA DVLD--ADGRTRETFNNYVREVGTYGQLDHERKSLGGK-----QGGGMYLMYEFKRDPGE
CDC65_HALSA EEID--ADQMTRETYVKYVKELSTYGLVSTARKSRG-------RGGGMYMDFTFRGDPES
CDC62_SACS2 REFN--EEPRRHTQVYEYLRKLKVIGIINTRQSGKGM--------RGRTTLVSLSLPLDK
CDC62_SULTO KDLG--EIPRKHTQVFEYIRKLKLMGLITARQSGKGM--------RGRTTLISLSVPISE
CDC62_ARCFU SEIK-----MSYRKYYNILEKLERLKLIEISFGEKGR---------GKTRYVQGKYDAEV
Q8ZYK1_PYRAE EEYG--ERPRVHSQLWSYLNDLREKGIVETRQNKRGE------GVRGRTTLISIGTEPLD
D3SXD8_NATMM EKVG--LNQVSERRVRDFLWPFEEEGVVSVERHNAGRQGEKTGERGGIWHTYSLEVPAPE
A1RWU5_THEPD NKFG--EKPLRYTRIWEKVQFLKKMGLVDTRTGRGET--------RGRTTMITFPGLPAN
B1L5M7_KORCO EELG--VIPYKYTAVWKRVRELRNMGFMEAKRSGEGMK--------GQSTLISLGSIPAE
A9A2Q2_NITMS KIISPDTRQISYRRFSEMLVELVNSGIAVSKTESKGR--------HGYGSQFKLSVDPEL
K0IKH7_NITGG ETYR--SKPADNRSVREYLLDLSRIGFLDIKNAKSKL--------EASIHDVPIGILLEV
K0IN17_NITGG ERLG-----MKKIDVEDYLDDLKARRLVDIRSLKEIG-----------LHGASLAELEPA
Q18F92_HALWD RKRD--LKPLSNRRISDYIQHLKLHGLIETKTYYGGK--------HGKTTQIQPSSLLQ-
:
CDC6C_HALMA VLERL----------------------------------------------
CDC66_HALSA VLERL----------------------------------------------
CDC62_METAC ILNCLKKG-------------------------------------------
CDC62_METMA ILNCLKKA-------------------------------------------
Q2FR23_METHJ ILFYL----------------------------------------------
CDC62_METTH LRRCPGF--------------------------------------------
CDC61_SACS2 IVRSLIESDSRFADLWS----------------------------------
CDC61_SULTO VIKAISEKDSKIASLWDR---------------------------------
CDC61_AERPE VENALSE-DPFVARLL-----------------------------------
CDC6D_HALMA TEAVLLS-DSRLGDIDDVQPFVQARFDN-----------------------
CDC67_HALSA TEAVLEA-DSRLSDIEDITPFVQARFENN----------------------
CDC61_METAC TRKVLLE-DYRLKPLVDFKTAVFNKMFS-----------------------
CDC61_METMA TRKVLLE-DYRLKPLVDFKASVFNKMFS-----------------------
CDC6_PYRAB IRNVFRY-DYAIQPLLTVSLKGGQRRLL-----------------------
CDC6_PYRHO IRNVFRY-DYTIQPLLAISLKDSQRRLV-----------------------
CDC6_PYRFU IRNVLRY-DYSIQPLLTISLKSEQRRLI-----------------------
CDC61_ARCFU LRKALEE-DYRLQNLRKFEGELKKLANLNLFQF------------------
CDC62_THEAC IKKYLLE-DENLSMFKSSKMPKQTRFDT-----------------------
CDC6_THEVO IKKYLME-DENLSMFKTSKMTKQARFDS-----------------------
CDC6_PICTO IKNYILE-DENFKNFQGSRIVRQSKLRTNYDDI------------------
Q74MI0_NANEQ IDL------------------------------------------------
CDC63_SACS2 VLRALNETFEDSISIGDFDDVGEN---------------------------
CDC63_SULTO IRKAL----EDTMNLGFEEQW------------------------------
CDC6Z_METTF PDLMLEAIRRSL---------------------------------------
CDC6V_METTF PELMLEAIRRSL---------------------------------------
CDC61_METTH TSLLEDSLWGV----------------------------------------
CDC6O_HALMA AIEAMSDVLHLTTEIDTIRDIAAMNNVG-----------------------
CDC6A_HALSA AVDAMADVLMLDAEIEKMEGLASRNGVL-----------------------
CDC6G_HALMA VGDVVRDFDSIALPTSVATQIT-----------------------------
CDC6K_HALMA ILAALEKTVDDVGIHKSVTNLVDAEATLSDFQST-----------------
CDC6B_HALMA VVDALQTIIGEFGAHQSIIEYLPDSGEEFATM-------------------
CDC68_HALSA VQEAIADADDATV--------------------------------------
CDC6A_HALMA AQEVLQEDERLAELFATDETSTTLDSF------------------------
CDC6H_HALMA IINAALQSSYSDAVPSNVNGILEHYLEDEATEFEAPDTTDDEQQNLWQFT-
CDC6Q_HALMA VLTLGN---------------------------------------------
CDC6I_HALMA VFKMNPGSAQVDTDR------------------------------------
CDC64_HALSA VRETILEDSRMQDWTRE----------------------------------
CDC6M_HALMA TRTGLINSTPELQTLMGW---------------------------------
CDC6N_HALMA IKKRLEQDERIADLSHHEDGLNRVIQAQKRNFAED----------------
CDC65_HALSA MMHRVVDDTRLERVGTESERLHAVVNAQLREFEE-----------------
CDC62_SACS2 RLDDYIMQQIMVRLKSRA---------------------------------
CDC62_SULTO ELDNLINNEIRDRLLQQKNY-------------------------------
CDC62_ARCFU VDRAMQLI-------------------------------------------
Q8ZYK1_PYRAE TLEAVITKLIKEELR------------------------------------
D3SXD8_NATMM IVEAARSAFTPFQKLITYEEESNWENYDR----------------------
A1RWU5_THEPD SVVGINRIPLDLLEKILRDSIEKELSSRGEERGEELTE-------------
B1L5M7_KORCO RLAEKLKEILREDLSPLPSSF------------------------------
A9A2Q2_NITMS IGNSCFPDWWPSVVESKKKKEAAAQASKRLKLLSSGRRSSSLGNLYRTLGF
K0IKH7_NITGG LEPMVAKEHSD----------------------------------------
K0IN17_NITGG LMNRIKGGEK-----------------------------------------
Q18F92_HALWD ---------------------------------------------------