CLUSTAL format seed alignment for MF_01408
_____________________________________________________________________________
Features found in the protein:
- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
THYX_SYNY3 ----------------------------------------------MD--------VRFI
THYX_HELPY ----------------------------------------------ME--------VICK
THYX_HELPJ ----------------------------------------------ME--------VICK
THYX_CAMJE ----------------------------------------------MQ--------ITLL
THYX_CAMJR ----------------------------------------------MQ--------ITLL
THYX_WOLSU ----------------------------------------------MT--------VTLM
THYX_PYRAE ----------------------------------------MVILETPR--------VFLI
THYX_TROW8 ------------------------------------------MFFVMDPVFLSEITVELV
THYX_TROWT --------------------------------------MLQCLFFVMDPVFLSEITVELV
THYX_STRAW --------------------------------------MTDTPADDLKPSFRSDVTVELV
THYX_STRCO --------------------------------------MTDIPADDPKIELRSDITVELV
THYX_BORBU ---------------------------------------MNKEYKILDNGF-----LKLI
THYX_THEMA -----------------------------------------MKIDILDKGF-----VELV
THYX_RUEPO -------MPLSSEQLAEIDAQRAHTAPTRRVVSPGMESHLYRAHPVLDHGF-----VRVI
THYX_GLUOX -------MALTSEQRAEIEAQRSEPQLTSRPTVAAMENLLFTPFEVLDHGF-----LRVV
THYX_ANAMM -------------------MEEGTGEYTKRVVVHALEDILHQELRVLDKGF-----VRVV
THYX_EHRRG ---------MLVLSIRIKVWQTMESEITKRIVVPELEDILYKEHKVLDKGF-----VRLV
THYX_EHRRW ---------MLVLSIRIKVWQTMESEITKRIVVPELEDILYKEHKVLDKGF-----VRLV
THYX_WOLPM -----------------------MNEATKRTIVKEIDAILYEEHKVLDHGF-----IRVV
THYX_RICPR -----------------------MHNTTKRVTVPALEAMLYETIKVLDHGF-----IRVI
THYX_RICTY -----------------------MHNTTKRVTVPALEAMLYETIKVLDHGF-----IRVI
THYX_RICBR -----------------------MNNATKRVVVPALEEILYEPIKVLDHGF-----IRVI
THYX_RICCN -----------------------MHNTTKRVTVPALEEILYEPIKVLDYGF-----IRVI
THYX_RICFE -----------------------MHNTTKRVTVPALEEILYEPIKVLDHGF-----IRVI
THYX_THET2 -------------------------------------MEGPLTIPVLDKGF-----VRLV
THYX_THET8 -------------------------------------MEGPLTIPVLDKGF-----VRLV
THYX_TREDE ---------------------------------------MDKEFKVLDKGF-----IRLV
THYX_TREPA MTLRTLQAGVAVSIALDRVCFFCYNGAVAHCVVEAAEDILDRRFSVLDKGF-----VRLI
THYX_HALMA ----------------------------------------------MD--------VKLL
THYX_HALSA ----------------------------------------------MR--------VRLL
THYX_MYCLE ----------------------------------------MAQIAPLR--------VQLI
THYX_MYCPA ----------------------------------------MAEIAPLR--------VQLI
THYX_MYCTU ----------------------------------------MAETAPLR--------VQLI
THYX_MYCBO ----------------------------------------MAETAPLR--------VQLI
THYX_CORDI ----------------------------------------MAQQSLLD--------VQLV
THYX_COREF ----------------------------------------MTEPVELS--------VELI
THYX_CORGL ----------------------------------------MAEQVKLS--------VELI
THYX_THEKO ----------------------------------------------MDNGIR----VKLV
THYX_PYRHO ---------------------------------------------MVK--------VKLI
THYX_PYRAB ---------------------------------------------MVR--------VTLV
THYX_PYRFU ---------------------------------------------MVR--------VTLV
THYX_SULAC ----------------------------------------------MK--------IKLV
THYX_SACS2 ---------------------------------------------MIS--------VKLV
THYX_SULTO ----------------------------------------------MN--------VKLV
THYX_DESVH -----------------------------------------MPRTEPR--------VELL
THYX_GEOSL ----------------------------------------------MK--------IALL
THYX_CLOPE ---------------------------------------------MLK--------VKLL
THYX_CLOTE ---------------------------------------MRGKTMGVK--------VKLL
:
THYX_SYNY3 SLTKPEIVIDGE------PLSPEGLIAYCARVS---------------SPNQENPNYTK-
THYX_HELPY HY------------------TPLDIASQAIRTCWQSF-----------EYSDDGGCKDKE
THYX_HELPJ HY------------------TPLDIASQAIRTCWQSF-----------EYSDDGGCKDRD
THYX_CAMJE FH------------------TPLSVCSHATRTCWQSF-----------EKGDCGGEKDKE
THYX_CAMJR FH------------------TPLSVCSHATRTCWQSF-----------EKGDCGGEKDKE
THYX_WOLSU QH------------------TSLTICAHAIRTCWQSF-----------EKSDGGGEKDRE
THYX_PYRAE AS-----------------WGSEAVISAFTDALYRGVPW---------EEAVKAQAPDVI
THYX_TROW8 KH-----------------SASDSDVVFSARVSTLGSFV---------AVTDCLSNRDIG
THYX_TROWT KH-----------------SASDSDVVFSARVSTLGSFV---------AVTDCLSNRDIG
THYX_STRAW KH-----------------SAADSDVLWAARVSTAGEQSL--------DELKKDPERSKG
THYX_STRCO KS-----------------AATDSDVLFAARVSTAGEQSL--------DELKKDPERSKG
THYX_BORBU DF-----------------MGDDRRIVKAARISY--------------REESVK-RKDAE
THYX_THEMA DV-----------------MGNDLSAVRAARVSF--------------DMGLKDEERDRH
THYX_RUEPO DY-----------------MGDDAAICQAARVSY--------------GTGTKSVQNDEG
THYX_GLUOX DY-----------------MGDDGAVVQAARVSY--------------GRGTKKVSEDAG
THYX_ANAMM DY-----------------MGSDESVVQAARVSY--------------GRGTKRTSQDAA
THYX_EHRRG DY-----------------MGSDESVVQAARISY--------------GRGTKSVSQDAA
THYX_EHRRW DY-----------------MGSDESVVQAARISY--------------GRGTKSVSQDAA
THYX_WOLPM DY-----------------MGSDSAIVQAARVSY--------------GKGTKQISQDEA
THYX_RICPR DY-----------------MGDDSSIVQAARVSY--------------GKGTKQLNQDKG
THYX_RICTY DY-----------------MGDDSSIVQAARVSY--------------GKGTKQLNQDKG
THYX_RICBR DY-----------------MGDDSAIVQAARVSY--------------GKGTKQLNQDKG
THYX_RICCN DY-----------------MGDDSAIVQAARVSY--------------GKGTKQLNQDKG
THYX_RICFE DY-----------------MGDDSAIVQAARVSY--------------GKGTKQLNQDKG
THYX_THET2 DQ-----------------MGDDRAIVQAARVSY--------------GEGTKTVREDAA
THYX_THET8 DQ-----------------MGDDRAIVQAARVSY--------------GEGTKTVREDAA
THYX_TREDE DY-----------------MGTDARIVQSARVSY--------------GEGTKTVREDAA
THYX_TREPA DY-----------------LGGDARIVQAARVSY--------------GAGTRTARDDAA
THYX_HALMA EA----------------TDDPEDLICKAARNDYSDTSVGSQSFEATMAEVDGDSLEEKK
THYX_HALSA EA----------------TENPEELICQSARNDYMSDWVGDTPLDTAMASVDGDTTDEKL
THYX_MYCLE AKTEFLAPPDVSWTTD--ADGGSALVEFAGRACYQS--W---------SKPNPRTATNAA
THYX_MYCPA AKTDFLAPPDVPWSTD--ADGGPALVEFAGRACYQS--W---------SKPNPKTATNAG
THYX_MYCTU AKTDFLAPPDVPWTTD--ADGGPALVEFAGRACYQS--W---------SKPNPKTATNAG
THYX_MYCBO AKTDFLAPPDVPWTTD--ADGGPALVEFAGRACYQS--W---------SKPNPKTATNAG
THYX_CORDI ACSTFTTPSGVDWKVDSAATDSEALVEFAGRACYET--F---------DKPNPRTAANDA
THYX_COREF ACSSFTPPASVAWDTD--AHGAEALVEFAGRACYETF-----------DKPNPRTATNAA
THYX_CORGL ACSSFTPPADVEWSTD--VEGAEALVEFAGRACYETF-----------DKPNPRTASNAA
THYX_THEKO NY----------------TKKPLETVTWAALISYWDEWE---------TETFGRMSDKDV
THYX_PYRHO NY----------------TPKPLETVTWAALISYWDGWS---------TEAFEKISPNDV
THYX_PYRAB NY----------------TRRPLETITWAALVSYWDEWS---------TESFEKINEDDV
THYX_PYRFU NY----------------TKRPLETITWAALISYWGEWS---------TESFERISENDV
THYX_SULAC SY----------------SKDGERIVAIAAKMSRSRKGW---------DYHEKEMTDDEI
THYX_SACS2 SY----------------TNDGEKVIAIAAKMSRSRKGW---------DYHEKDMTDDEI
THYX_SULTO SY----------------TRDGEKVVAIASKMSRSRKGW---------DYHEKTMTDEEI
THYX_DESVH AH----------------TPEPLSLLYAAFRQCYHAGFVADMWP----RLLSGEIEREKQ
THYX_GEOSL QH----------------TPDPEAAVALAARLCYASVGI---------DELREKLSASDV
THYX_CLOPE QY----------------TPEPEKTIAAAAKLCYSPVGV---------DDILENLTDEGA
THYX_CLOTE EY----------------TPNPEKVVASAAKLCYSPVGV---------EEMAKDLSEEKV
THYX_SYNY3 --LLQFC-IREGHWSIFEMVDMTLEIT-TTRAIAPQILRHRSF-SFQEFSLRYSCATEYE
THYX_HELPY --LIHRVGNIFRHSSTLEHLYYNFEIKGLSRGALQELSRHRIA-SLSVKSSRYTLRELKE
THYX_HELPJ --LIHRVGNIFRHSSTLEHLYYNFEIKGLSRGALQELSRHRIA-SLSVKSSRYTLRELKE
THYX_CAMJE --LIDRVGNKFKHASTLEHLNYTFYIQGISRACLQEVARHRHT-SPSVKSTRYTLKELRN
THYX_CAMJR --LIDRVGNKFKHASTLEHLNYTFYIQGISRACLQEVARHRHT-SPSVKSTRYTLKELRN
THYX_WOLSU --LIDRVGNKNKHASTLEHLVYTFYIQGISRACLQELARHRIA-SLSVKSSRYTLKELKA
THYX_PYRAE IKRISAF-YRQGHWSVFEFMGAQFLVE-CSRACHTQFIRHRMA-SYWSESQRYVDYTKRE
THYX_TROW8 --LITFL-MRERHGSPFEHSHMTFRIS-APIFVFREFMRHRIA-SYNEESGRYKNLDPVF
THYX_TROWT --LITFL-MRERHGSPFEHSHMTFRIS-APIFVFREFMRHRIA-SYNEESGRYKNLDPVF
THYX_STRAW --LINYL-MRDRHGSPFEHNSMTFFIS-APIFVFREFMRHRVGWSYNEESGRYRELEPVF
THYX_STRCO --LINYL-MRDRHGSPFEHNSMTFFVS-APIFVFREFMRHRVGWSYNEESGRYRELQPVF
THYX_BORBU --LIDYL-IRNGHTSPLEQVVFTFHVK-APIFVARQWMRHRTA-RINEVSGCYSLAREEF
THYX_THEMA --LIEYL-MKHGHETPFEHIVFTFHVK-APIFVARQWFRHRIA-SYNELSGRYSKLSYEF
THYX_RUEPO --LIRYL-MRHWHSTPFEMCELKLHVK-LPVFVARQWIRHRTA-NVNEYSARYSILDREF
THYX_GLUOX --LIRYL-MRHRHSTPFEMCEIKFHVK-LPVFVARQWIRHRMA-SVNEYSARYSILDREF
THYX_ANAMM --LIGYL-MRHAHTSPFEMCEIKLHVK-LPIFVARQWVRHRTA-SINEYSARYSVLDREF
THYX_EHRRG --LINYL-MRHSHTTPFEMCEIKFHIK-LPIFVARQWVRHRTA-NVNEYSARYSVLDHEF
THYX_EHRRW --LINYL-MRHSHTTPFEMCEIKFHIK-LPIFVARQWVRHRTA-NVNEYSARYSVLDHEF
THYX_WOLPM --LIKYL-MRHHHTTPFEMCEIKFHVK-LPIFVARQWIRHRTA-NVNEYSARYSILDNEF
THYX_RICPR --LINYL-LRHYHTTPFEMCDIKFHIK-LPIFIARQWIRHRTA-SVNEYSARYSILGNEF
THYX_RICTY --LINYL-LRHYHTTPFEMCDIKFHIK-LPIFIARQWIRHRTA-SVNEYSARYSILGNEF
THYX_RICBR --LINYL-LRHYHTTPFEMCDIKFHIK-LPIFIARQWIRHRTA-SVNEYSARYSILGNEF
THYX_RICCN --LINYL-LRHYHTTPFEMCDIKFHIK-LPIFIARQWIRHRTA-SVNEYSARYSILGNEF
THYX_RICFE --LINYL-LRHYHTTPFEMCDIKFHIK-LPIFIARQWIRHRTA-SVNEYSARYSILGNEF
THYX_THET2 --LIDYL-MRHRHTSPFEMVVFKFHVK-APIFVARQWFRHRTA-SVNEISGRYSILKEEF
THYX_THET8 --LIDYL-MRHRHTSPFEMVVFKFHVK-APIFVARQWFRHRTA-SVNEISGRYSILKEEF
THYX_TREDE --LIDYL-LRNKHTSPFEQVVFTFHVK-LPIFVARQWIRHRTA-RLNEISGRYSILKAEF
THYX_TREPA --LIDFL-LRNKHTSPFEQVVLTFHVR-APIFVARQWMRHRTA-RISEVSSRYSLLSHDC
THYX_HALMA ETLIGHL-LDHGHFGPFEHAQATFAVEGVSRSCMAQITRHRHV-SFDVQSMRYVSFDDVD
THYX_HALSA SNLIAQL-LTRGHYGPFEHPSATFAIEGVSRSCMAQLTRHRHA-SFDVQSMRYVAFDDVD
THYX_MYCLE --YIKHI-IDVGHVAVLEHASVSFYISGISRSCTHELIRHRHF-SYSQLSQRYVPEKDAQ
THYX_MYCPA --YIKHI-IDVGHFSVLEHASVSFYITGISRSCTHELIRHRHF-SYSQLSQRYVPENDSR
THYX_MYCTU --YLRHI-IDVGHFSVLEHASVSFYITGISRSCTHELIRHRHF-SYSQLSQRYVPEKDSR
THYX_MYCBO --YLRHI-IDVGHFSVLEHASVSFYITGISRSCTHELIRHRHF-SYSQLSQRYVPEKDSR
THYX_CORDI --YIRHI-MEVGHMALLEHPTATVYIRGLSRSATHELVRHRHF-SFSQLSQRFVHSDETH
THYX_COREF --YLRHI-MEVGHTALLEHASATMYIRGISRSATHELVRHRHF-SFSQLSQRFVHEGEQE
THYX_CORGL --YLRHI-MEVGHTALLEHANATMYIRGISRSATHELVRHRHF-SFSQLSQRFVHSGESE
THYX_THEKO EMHLPRV-LGYGHESILEHATLTFAIEGCSRVCSHQLVRHRLA-SYTQQSQRYIVLNPED
THYX_PYRHO EIHLPRI-LSYGHESILEHATFTFSIEGCSRVCTHQLVRHRIA-SYTQQSQRYIKINPED
THYX_PYRAB KAHLPRI-LGYGHESILEHATFTFSIEGCSRVCTHQLVRHRIA-SYTQQSQRYIVLNEEN
THYX_PYRFU EKHLPRI-LGYGHESILEHATFTFSIEGCSRVCTHQLVRHRIA-SYTQQSQRYIVLDEEN
THYX_SULAC ETWIRDS-ITHGYWSVLEHSVYTFSIEGISRVASHQLVRHRIA-SYTQMSHRFAKPVDKY
THYX_SACS2 ETWIRDA-ILHGYWSVLEHSVYTFSIEEISRVASHQLVRHRIA-SYTQMSHRFAKPIDEY
THYX_SULTO EVWIRDA-ILHGYWSVLEHSIYTFSIEGISRVASHQLVRHRVA-SYTQMSHRFAKPIDEY
THYX_DESVH GAFIASI-LESGHSSPIEHVSFTFAIEGVSRALTHQLVRHRIA-SFSQQSQRYVDGSHFD
THYX_GEOSL TAFLDKI-MSLGHQSVLEHASFTFGIEGISRAASHQLVRHRIA-SYSQQSQRYVTFRGDG
THYX_CLOPE EKFLNML-MSYGHMSPIEHVSFTFAVEGVSRSLTHQLVRHRIA-SYSQQSQRYVKLDQFE
THYX_CLOTE NKFLNML-MSYGHESPIEHVSFTFAAEGVSRSLTHQLVRHRIA-SYSQQSQRYVKLDQFQ
: : :* . . : *** * :
THYX_SYNY3 C--------YEARRQDVKNRQNSLDDFDESTKKWFNQAQAAVWEKSHQL----YEEALA-
THYX_HELPY VE------SFLPLNETNLERAKEFLVFVDN----------EKVNAMSVLALENLRILLSE
THYX_HELPJ VE------SFLPLNETNLERAKEFLVFVDD----------EKVNEMSVLALENLRVLLSE
THYX_CAMJE EA------EFKIGDFENASRYLVLC-------------GNEEVDNASIKALENLRTILQ-
THYX_CAMJR EA------EFKIGDFENASRYLVLC-------------GNEEVDNASIKALENLRTILQ-
THYX_WOLSU EE------EFKEGDWERAKRYLVE-------------TESEAVNLASLKALENLRQVLL-
THYX_PYRAE IR------FVVPKGFPADL---------------------------LKRAYEDYARLR--
THYX_TROW8 YI-------PDEKRKLVQIGAPGAYKFEEGTS-EQYGLLIEEMKELSLAAYDTYKRLLA-
THYX_TROWT YI-------PDEKRKLVQIGAPGAYKFEEGTS-EQYGLLIEEMKELSLAAYDTYKRLLA-
THYX_STRAW YV-------PGESRKLVQEGRPGKYVFVEGTQ-AQQELTGRVMEDSYRQAYEAYQEMLA-
THYX_STRCO YA-------PDASRKLVQQGRPGKYVFVEGTP-EQHELVGSAMEDSYRQAYATYQQMLA-
THYX_BORBU YV-------PLEEDLKCQTSSNSSEKEFKSL-----EKLSDKIKHHQKHSYELYQDMIN-
THYX_THEMA YI-------PSPERLEGYKTTIPPE------------RVTEKISEIVDKAYRTYLELIE-
THYX_RUEPO YI-------PAPEHVAAQSAVNNQGR-GEALQGEEAARVLEILKADSARCYDNYEAMIGQ
THYX_GLUOX YL-------PAMDQVAAQSSSNRQGR-SDALDADTAHQVLEILRRDASQCYDDYESLLNP
THYX_ANAMM YI-------PDEKQIAEQSTNNAQGR-GTPLPADAAKRIMELFRRNSELMYEDYEALLE-
THYX_EHRRG YI-------PELDHVATQSEDNAQGR-GNSLSNEDAQYVTDLLKRDSDMVYETYNKFLI-
THYX_EHRRW YI-------PELDHVATQSEDNAQGR-GNSLSNEDAQYVTDLLKRDSDMVYETYNKFLI-
THYX_WOLPM YT-------PKPEQVAKQSDNNKQGS-GEAFDPDTSKEIIDSLINDSNLVYSHYEKFIE-
THYX_RICPR YL-------PDPANIASQSVVNKQCRAGDSVPKKVSEKVLAILEEDARRCYRHYKELMNA
THYX_RICTY YL-------PEPTDIASQSAINKQCRAGDSLPKKVSEKVLAILEEDARRCYMHYKELMNA
THYX_RICBR YL-------PEPQNIAPQSSTNKQCRESDSLPKEVAEKVLNILEEDARNCYKHYTKLMNT
THYX_RICCN YL-------PEPANIASQSAVNKQCREGDSLPKEVAEKVLAILEEDARQCYGHYKELMNA
THYX_RICFE YL-------PEPANIASQSAVNKQCREGDSLPKEGAEKVLAILEEDAKQCYGHYKELMNA
THYX_THET2 YE---------PEAFRKQAKRNKQASEGALLDE----EALALLRKVEQEAYGAYRALLE-
THYX_THET8 YE---------PEAFRKQAKRNKQASEGALLDE----EALALLRKVQQEAYGAYRALLE-
THYX_TREDE YV-------PAGKDIALQSSDNKQGRMNEAVPQDLQNEVITSLQKQQEEIYAGYSKLLD-
THYX_TREPA YV-------PQETSVAVQSTRNKQGRASEGISPEQQQEVRAAFEAQQKAACAAYDALIQ-
THYX_HALMA PEAVREGELVVTPPSATDPDWIGRNQQKASVSDEEFEERAEIFKDTIEQAVESYQELLE-
THYX_HALSA PAAVAEGELVVTPPSATDPDWVGRNQDAGDIDEETMAEREAVFQASVRRAVEDYQELLG-
THYX_MYCLE VV--------VPPDMEDDD------------------ELQQILIAAVEASRATYTELLVK
THYX_MYCPA VV--------VPPGLDDDP------------------ELQQILAAAADASRATYTELLAR
THYX_MYCTU VV--------VPPGMEDDA------------------DLRHILTEAADAARATYSELLAK
THYX_MYCBO VV--------VPPGMEDDA------------------DLRHILTEAADAARATYSELLAK
THYX_CORDI VV--------IPPLIDNDP------------------QLRELFLSTVDEVRFAYSELMTA
THYX_COREF VI--------IPELINEDP------------------QLRSLFLRAMDDNRFVYNELLNA
THYX_CORGL VV--------VPTLIDEDP------------------QLRELFMHAMDESRFAFNELLNA
THYX_THEKO VE----ETFVIPSGIKEDP------------------ELLAEWKELMKKSIELYKKSVE-
THYX_PYRHO VE----ETFVIPESIKKDS------------------ELLKEWKELLKRSLELYEKSIE-
THYX_PYRAB VE----ETFVIPESIKKDR------------------ELYEKWKKAMAETIKLYKESLK-
THYX_PYRFU VE----ETFVIPESIKKDR------------------ELYEKWKKVMAETISLYKESIN-
THYX_SULAC YK------PITPPSIEK--------------------RGKEVVDKAYQDAYNYFYQLLE-
THYX_SACS2 YK------PIIPPSAKK--------------------RSKELVEKAYKEAYDNYYTLLE-
THYX_SULTO YK------PITPPSIEK--------------------RAKEIIEKAYQEAYENYFKLLQ-
THYX_DESVH YV--------MPPAIARNA------------------AAKARFEQFMEDVGSAYRDIKAL
THYX_GEOSL FP------RVVPGSVSATE------------------KRRQVFESAMQACADAYRALVD-
THYX_CLOPE YI--------VPPAIENDE------------------VAKKLFIDQMQGAQKAYDEIVER
THYX_CLOTE YI--------IPPEIDKDN------------------NTRSIFIEAMENSQKAYDKIAST
THYX_SYNY3 -----------KGI--------AKECARSILPLNTVTRLYMKGSVRS-WIHYFSVRCD--
THYX_HELPY -----------HNI--------KNDLAKYAMPESYKTHLAYSINARS-LQNFLTLRSS--
THYX_HELPJ -----------HNI--------KNDLAKYAMPESYKTHLAYSINARS-LQNLLTLRSS--
THYX_CAMJE -----------KSI--------SLDIAKYCLPESYKTELTLTINARS-LQNFISLRSS--
THYX_CAMJR -----------KSI--------SLDIAKYCLPESYKTELTLTINARS-LQNFISLRSS--
THYX_WOLSU -----------LGI--------SNDMAKYCLPESYKTELTWTINARA-LQNFLTLRSS--
THYX_PYRAE -----------EGF--------RPEYARMILPNATAVLFAVQMNARELLLNFAPLRCA--
THYX_TROW8 -----------CGI--------AREVARMILPLNLYSTMYVTINARS-LMNFLSVRTSRA
THYX_TROWT -----------CGI--------AREVARMILPLNLYSTMYVTINARS-LMNFLSVRTSRA
THYX_STRAW -----------AGV--------AREVARAVLPVGLFSSMYATCNARS-LMHFLGLRTQHE
THYX_STRCO -----------AGV--------AREVARAVLPVGLYSSMYATCNARS-LMHFLGLRTQHE
THYX_BORBU -----------ANI--------PKELSRIVLPLSLYTEWYWQIDLNN-LFHFIKLRLA--
THYX_THEMA -----------SGV--------PREVARIVLPLNLYTRFFWTVNARS-LMNFLNLRAD--
THYX_RUEPO EGQ--------QGL--------ARELARMNLPANIYTQWYWKVDLHN-LFHFLRLRAD--
THYX_GLUOX EG---------RGL--------ARELARINLTLNTYTQWYWKIDLHN-LMHFLALRAD--
THYX_ANAMM -----------QGL--------ARELARMNLTINCYTQWYWKVNLHN-LLRFLALRSG--
THYX_EHRRG -----------KGV--------SREISRISLTLNYYTEWYWKIDLHN-LLHFLRLRSD--
THYX_EHRRW -----------KGV--------SREISRISLTLNYYTEWYWKIDLHN-LLHFLRLRSD--
THYX_WOLPM -----------QGL--------AREIARTNLMLNYYTQFYWKIDLHN-LLHFLKLRAD--
THYX_RICPR DEDGNILDENVSGI--------ARELARINLTLNYYTEWYWKINLHN-LLHFLRLRTD--
THYX_RICTY DEDGNIIDENVAGI--------ARELARMNLTLNYYTEWYWKINLHN-LLHFLRLRTD--
THYX_RICBR DEEGNIIDDNNTGI--------ARELARMNLTLNYYTEWYWKINLHN-LLHFLRLRAD--
THYX_RICCN DEEGNIIDENATGI--------ARELARMNLTLNYYTEWYWKINLHN-LLHFLRLRAD--
THYX_RICFE DEDGNIIDENNTGI--------ARELARMNLTLNYYTEWYWKINLHN-LLHFLRLRAD--
THYX_THET2 -----------KGV--------AREMARMVLPLNLYTEFYWKQDLHN-LFHFLKLRLA--
THYX_THET8 -----------KGV--------AREMARMVLPLNLYTEFYWKQDLHN-LFHFLKLRLA--
THYX_TREDE -----------KNI--------ARELARINLPLSTYTEWYWQIDLHN-LFHFLRLRMD--
THYX_TREPA -----------KNI--------ARELARINVPLSLYTEWYWQIDLHN-LFHFLRLRAS--
THYX_HALMA -----------LGM--------PPEDARFVLPIGTKVNIVMSMNARM-LMHVADMRAA--
THYX_HALSA -----------LGM--------PPEDARFVLPIGTEVNVVITLNPRS-LMHVADMRAA--
THYX_MYCLE LNA-KLMAGELGGNRAVLRRKQARQAAHAVLPNANETRIVVTGNYRA-WRHFIAMRAS--
THYX_MYCPA LEA-KFADQP-SAV---LRRKQARQAARAVLPNATETRIVVTGNYRA-WRHFIAMRAS--
THYX_MYCTU LEA-KFADQP-NAI---LRRKQARQAARAVLPNATETRIVVTGNYRA-WRHFIAMRAS--
THYX_MYCBO LEA-KFADQP-NAI---LRRKQARQAARAVLPNATETRIVVTGNYRA-WRHFIAMRAS--
THYX_CORDI LDN-KLADEP-NAI---LRRKQARQAARSILPNATESRIVVTGNFRA-WRHFIGMRAT--
THYX_COREF LEE-KLEGEP-NAL---LRKKQARQAARAVLPNATESRIVVTGNFRS-WRHFLGMRAS--
THYX_CORGL LEE-KLGDEP-NAL---LRKKQARQAARAVLPNATESRIVVSGNFRT-WRHFIGMRAS--
THYX_THEKO -----------RGQ--------HQEDARFILPQAVRTKIVVTMNLRE-LKHFLGLRAC--
THYX_PYRHO -----------RGI--------HQEDARFILPQSVKTKIVVTMNLRE-LKHFFGLRLC--
THYX_PYRAB -----------RGI--------HQEDARFILPQAVRSKIVVTMNLRE-LKHFFGLRLC--
THYX_PYRFU -----------RGV--------HQEDARFILPQAVKTKIIVTMNLRE-LKHFFGLRLC--
THYX_SULAC -----------KGV--------PEEDARYVLPNGVNTNIVVTMNARE-LYNFFGLRLC--
THYX_SACS2 -----------SGV--------PEEDARYVLPNGVNTNIVVTMNARE-LYNFFSLRLC--
THYX_SULTO -----------DGV--------PEEDARYVLPNGVNTNIVVTMNARE-LYNFFALRLC--
THYX_DESVH LEQ--------DGR----TGSRANEDARFVLPQAAASKIVVTMNCRA-LVHFFEERCC--
THYX_GEOSL -----------DGV--------PAEDARFVLPNAAETKIIVTMNARE-LIHFFGLRCC--
THYX_CLOPE LKD-KYIS---EGIGEKPAEKKAIEDARYVFPNACETKIVFTMNARS-LMNFFHHRCC--
THYX_CLOTE LEQ-KYIS---EGMKRKEAEKKAIEDARYVFPNACETKIIFTMNART-LMNFFRHRCC--
: :: . . . . *
THYX_SYNY3 -----QATQKEH--------REIALAAR----KIF---MKHFPTV-AAALE---------
THYX_HELPY -----NKALKEM--------QDLAKALF----DAL-------PGE-HQYLFEDCLKH---
THYX_HELPJ -----NKALKEM--------QDLAKALF----DAL-------PYE-HQYLFEDCLKH---
THYX_CAMJE -----KSALWEI--------RNLANALF----EAL-------PQE-HKFIFEHCLHKDIE
THYX_CAMJR -----KSALWEI--------RNLANALF----EAL-------PQE-HKFIFEHCLHKDIE
THYX_WOLSU -----KSALWEI--------RKLAKTLH----EAL-------PKE-HRYL--FCLNQEG-
THYX_PYRAE -----YAAQAEI--------RHVCWQMFAHAWRLW---PNLARLV-WEDLPSLHRDFCTK
THYX_TROW8 NSAFHSYPQREI--------ELCADRIE----EIW---KGLMPET-HAAFEKQGRVAP--
THYX_TROWT NSAFHSYPQREI--------ELCADRIE----EIW---KGLMPET-HAAFEKQGRVAP--
THYX_STRAW LAKVPSFPQREI--------EMVGEKME----AEW---AKLMPLT-YAAFNTNGRVAP--
THYX_STRCO LAKVPSFPQREI--------EMAGEKME----AEW---ARLMPLT-HAAFNANGRVAP--
THYX_BORBU -----LDSPKEIKENSPKEMREYAKALI----SIV---REIVPIA-FNSFENHFLRGKRF
THYX_THEMA -----SHAQWEI--------QQYALAIA----RIF---KEKCPWT-FEAFLKYAYKGDI-
THYX_RUEPO -----AHAQYEI--------RVYAETMC----RLV---ADWVPFA-YKAFEDYRLGAVNL
THYX_GLUOX -----PHAQYEI--------RVYAEKMI----EIL---KAWVPAT-AAAFEEYRLGAFTL
THYX_ANAMM -----AGAQYEI--------REYASRIL----EIV---RLWVPMV-HAAFVEYHLESSTI
THYX_EHRRG -----VHAQYEI--------RVYAETML----EIV---KKWVPLT-YAAFVEYCLESQSF
THYX_EHRRW -----VHAQYEI--------RVYAETML----EIV---KKWVPLT-YAAFVEYCLESQSF
THYX_WOLPM -----KHAQYEI--------RVYAEVML----DII---KKWVPLA-YNAFVEYCLESACI
THYX_RICPR -----PKAQYEI--------RVYAEKIL----DIV---KAWVPFT-YEAFEEYRLQGANI
THYX_RICTY -----SKAQYEI--------RVYAGKIL----DIV---KAWVPFT-YEAFEEYRLQGANI
THYX_RICBR -----PHAQYEI--------RVYAEKML----DIV---KAWVPFT-YEAFEEYRMCGANI
THYX_RICCN -----PHAQYEI--------RVYAEKML----EIV---KAWVPFV-YEAFEEYRLQGANI
THYX_RICFE -----PHAQYEI--------RVYAEKML----EIV---KAWVPFT-YEAFEEYRLQGANI
THYX_THET2 -----PEAQWEI--------RQYARAIA----EIV---KERVPLA-WAAFEEHLLEGAFL
THYX_THET8 -----PEAQWEI--------RQYARAIA----EIV---KERVPLA-WAAFEEHLLEGAFL
THYX_TREDE -----AHAQKEI--------RDYAEVMF----EIC---KTVTPLA-CASFERHEKNGVNF
THYX_TREPA -----AHAQAEI--------RAYAEVII----EIT---RAVAPCA-TASFENHEKDGVQF
THYX_HALMA -----ADAQWEI--------REMTEEML----ELA---ADWCPKT-FEYYEQEMKGRKN-
THYX_HALSA -----ADAQWEI--------RELTEQLL----DAA---AQWCPHT-FEYYDAEMKHRKN-
THYX_MYCLE -----EHADVEI--------RRLAIVCL----RRL---VDVAPAV-FADFEITALADGT-
THYX_MYCPA -----EHADVEI--------RRLAIECL----RRL---ADVAPAV-FADFEIATLADGT-
THYX_MYCTU -----EHADVEI--------RRLAIECL----RQL---AAVAPAV-FADFEVTTLADGT-
THYX_MYCBO -----EHADVEI--------RRLAIECL----RQL---AAVAPAV-FADFEVTTLADGT-
THYX_CORDI -----EHADVEI--------RSLAVRCL----EIL---KEKAPTV-FSDFETSVLSDGS-
THYX_COREF -----EHADVEI--------RAVAVACL----EKL---KQQAPTV-FGDFQVETLADGT-
THYX_CORGL -----EHADVEI--------REVAVECL----RKL---QVAAPTV-FGDFEIETLADGS-
THYX_THEKO -----ERAQWEI--------REVAWKML----EEIAKNDELRPIIKWAKLGPRCVQLGY-
THYX_PYRHO -----ERAQWEI--------REVAWKML----EEIAKRKELKPIIEWAKLGPRCIQLGY-
THYX_PYRAB -----ERAQWEI--------REVAWKML----EEIAKREELRPIIKWAKLGPRCIQLGY-
THYX_PYRFU -----ERAQWEI--------REVAWKML----EEMAKRDDIRPIIKWAKLGPRCIQFGY-
THYX_SULAC -----SRAQWEI--------RAIAWKML----DEV---KRVHPRL-FKYAGPNCIIHENF
THYX_SACS2 -----SRAQWEI--------RAIAWKML----EEV---KKVHPRL-FKYTGPNCIIHENF
THYX_SULTO -----SRAQWEI--------RAIAWKML----EEV---KKVHPRL-FRYVGPNCIIHENF
THYX_DESVH -----MRAQWEI--------RAVADVML----GLC---REVLPEL-FAHAGAKCERLGY-
THYX_GEOSL -----ERAQWEI--------RALAVEML----RLV---KGVAPTI-FRDAGPGCLTGP--
THYX_CLOPE -----DRAQWEI--------RTMAEKMV----NEV---KKVAPIL-FKNAGPSCVAGPCP
THYX_CLOTE -----TRAQWEI--------RNLANEML----SEV---KKVAPNL-FKYSGPSCVN-GN-
. * .
THYX_SYNY3 ---------------------------------------------W--------------
THYX_HELPY ------------------------------------------------------------
THYX_HELPJ ------------------------------------------------------------
THYX_CAMJE ------------------------------------------------------------
THYX_CAMJR ------------------------------------------------------------
THYX_WOLSU ------------------------------------------------------------
THYX_PYRAE VP---------------RGEDCRLYAIKDAEEKHGPLPETP----WLSALVHG-------
THYX_TROW8 ------------------------------------------------------------
THYX_TROWT ------------------------------------------------------------
THYX_STRAW ------------------------------------------------------------
THYX_STRCO ------------------------------------------------------------
THYX_BORBU SH---------------EEIIAIINALDLNKLSMDAEKL----NLLKDKLGID-------
THYX_THEMA -------------------------LKEVQV-----------------------------
THYX_RUEPO SA---------------QMVDSLRRMLAGEAVTQETSGLSA--REWREFQDVIGR-----
THYX_GLUOX SA---------------GMLKVVRRRLAGETVTQENSGLTK--REWSEMAAVLDGAS---
THYX_ANAMM SR---------------SALVVVRKMLQGEKVSMEESGLGR--REWGELMSVLYPDGEPE
THYX_EHRRG SK---------------SALSVVKKLIAGEDVAREDTGIGK--REWRELMDVLADK----
THYX_EHRRW SK---------------SALSVVKKLIAGEDVAREDTGIGK--REWRELMDVLADNK---
THYX_WOLPM SR---------------TGLEIIRKLIKGENVTREESNIGK--REWGELMSILDKQS---
THYX_RICPR SR---------------KGLEVIKRMIKGEKVIHETSGMNK--REWEELVKIFR------
THYX_RICTY SR---------------KGLEVIKRMIQGEKVIHETSGMNK--REWEELVKIFR------
THYX_RICBR SR---------------KGLEVIKKMISGEKVTHETSGMTK--REWEELTKILK------
THYX_RICCN SR---------------KGLDVIKRMINGEKVTHETSDMTK--REWEELMKIFG------
THYX_RICFE SR---------------KGLDVIKRMIKGEKVTHESSGMTK--REWEELMKIFG------
THYX_THET2 SR---------------TELRALRGLLTPEVYEKALSSLGLGGSRLKEALEKVFGPGEAL
THYX_THET8 SR---------------TELRALRGLLTPEVYEKALSSLGLGGSRLKEALEKVFGPGEAL
THYX_TREDE SA---------------EELEAIRNLIAGKDSGLKGKELERFNEKLKSGRQV--------
THYX_TREPA SG---------------REFAALKALLAGEGLSLEGKERAR----FEEKLRSGLQQ----
THYX_HALMA ------------------------------RLAP--------------------------
THYX_HALSA ------------------------------RLAP--------------------------
THYX_MYCLE --------------------EVATSPLATEA-----------------------------
THYX_MYCPA --------------------EVATSPLATEA-----------------------------
THYX_MYCTU --------------------EVATSPLATEA-----------------------------
THYX_MYCBO --------------------EVATSPLATEA-----------------------------
THYX_CORDI ----------------------------IMATSPYVTDY---------------------
THYX_COREF ----------------------------QMATSPYVTDF---------------------
THYX_CORGL ----------------------------QMATSPYVMDF---------------------
THYX_THEKO -------------------------CPEGELMPPGCWKRTG--EKWKTLFEG--------
THYX_PYRHO -------------------------CPERELMPPGCLKRTR--ERWKNLLEKY-------
THYX_PYRAB -------------------------CPERELMPPGCFKRTR--ERWMKLLEKPL------
THYX_PYRFU -------------------------CPERDLMPPGCLKKTR--KKWEKVAESKS------
THYX_SULAC IR--ENPITLDDI---DNTVFISQRCIEGVT----REGIPKCVKNARSILVSEDGVVMGK
THYX_SACS2 IRNENESITLEDIFKDYKLEFISQRCIEGVL----RDGIKKCIINSRSVLDNIK------
THYX_SULTO IR--NEPITLDEVLQKDNIEFISQRCIEGVM----RDGILKCIRNSKHVLEYLK------
THYX_DESVH -------------------------CPEGERFTCGRYPLRQ--SMP--------------
THYX_GEOSL -------------------------CPEGGM-TCGKAAEVK--RLFREMSI---------
THYX_CLOPE EG----------------------KMCCGKLKEMRTLYLGK-------------------
THYX_CLOTE -------------------------CPEG-AMSCGKAAEMK--KIYL-------------