CLUSTAL format seed alignment for MF_01409

_____________________________________________________________________________

Features found in the protein:
The following colors are used to highlight features:
blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
magenta is used to display DISULFID, THIOLEST and THIOETH.
red is used for all other features, such as INIT_MET, ACTIVE SITE,
 METAL,BINDING, NP_BIND, SITE, REGION, etc.
The ID of the sequence used as the template for feature propagation is 
underlined.
A '<' at the beginning of a sequence or '>' at the end indicate that
 the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________

HMGCS_METAC      ------------MTIGIVSYGAYVPRYRIKIEEIARLWGDDAEALKNGLMVYEKSVPDVD
HMGCS_METMA      ------------MTIGIVSYGAYVPRYRIKIEEIARLWGDDAEALKNGLMVYEKSVPDID
HMGCS_METBF      ------------MTIGIVSYGAYVPRYRIKVEEIARVWGDDANALKSGLMVYEKSVPDID
HMGCS_METBU      ------------MSVGIVSYGAYIPKFRIKVEDIARVWGDDADILSAGLMVYEKSVPDLD
HMGCS_METTP      ------------MGVGIVSYGVYIPRYRIKVDEIARVWGE-VEDIARGLNVYEKAVPDLD
HMGCS_METAR      ------------MKLGISAYGAYVPQYRIKVEEIAKVWGDDADDYRNGLMVSEKSVPDVD
HMGCS_THEAC      -------------MSGIVTYGSYIPRYRIKPDEIARVWGENPDHIKNGIYILSKSVPAPD
HMGCS_THEVO      -------------MSGIVTYGSYIPRYRIKPDEIARVWGENPERIKNGIFILSKSVPAPD
HMGCS_PICTO      -------------MSGIVTYGSYIPRYRIRPEEIARVWGEDPEKMKNGIFILSKSVPGPD
HMGCS_ARCFU      -------------MIGIVSYGSYVPKFRIRVEEIARVWGEDAKKIKDGLGVHEKSVPGMD
HMGCS_METS3      -------------MVGIVGYGAYVPSYRIKVEEIAKVWGDDPVALSRGLVVNEKSVPSAD
HMGCS_METST      -------------MTGIVGYGAHIPSYRIKVEEIAKVWGDDPKSISKGLVVNQKSVPGPD
HMGCS_METTH      -------------MAGIVGYGVYIPSYRIKVEEIARVWGDDPQAISRGLVVEEKSVPGPD
HMGCS_METM5      -----------MKEVGIVGYGSDLPKYRIKAEDIAGAWGKDAQAIKRGLVVNEKSVPGPD
HMGCS_METM7      -----------MKEVGIVGYGSDLPKYRIKAEDIAGAWGKDAQAIKRGLVVNEKSVPGPD
HMGCS_METM6      -----------MKEVGIVGYGSDLPKYRIKAEDIAGAWGKDAQAIKRGLIVNEKSVPGPD
HMGCS_METMP      -----------MKEVGIVGYGSDLPKYRIKAEDIAGAWGKDAQAIKRGLVVNEKSVPGPD
HMGCS_METVS      -----------MKEVGIVGYGSDLPKYRIKAEEIAKAWGKDAEAIKKGLVVNEKSVPGPD
HMGCS_METJA      -------------MAGIVGYGAYIPKYRIKVEEIARVWNKDPESIKKGLLVYEKAVPSLD
HMGCS_METKA      --------MIPSERVGIVGYGAYVPRYRIKAEEIAAVWGDDVDSIKSGLMIEEKSVPSET
HMGCS_PYRAB      ----MGKLLKPSKEIGIVGYGAYVPMYRIRNEEIGRVWGVSNFPIE------EKAVPGLD
HMGCS_PYRHO      ----MGKLLKPIKDVGIVGYGAYVPMYRIRNEEIGRVWGISNFPIE------EKAVPGLD
HMGCS_PYRFU      ----MRKVMKPMKDVGIVGYGAYVPMYRIRNEEIGRVWGVSSFPIE------EKAVPGLD
HMGCS_THEGJ      ----MRKLLKPKREVGIVGYGAYVPMYRIKAEEIGRVWGVSSFPIE------EKAVPGLD
HMGCS_THEON      ----MRKLLKPVKDVGIVGYGAYVPKYRIKAEEIGRVWGVSSFPIE------EKAVPGLD
HMGCS_THEKO      ----MSKLLKPKREVGIIGYGAYVPMYRIKAEEIGRVWGVSSFPIQ------EKSVPGLD
HMGCS_THESM      ----MRRLLKPIKDVGIVGYGAYVPMFRIKNEEIGRVWGVNGFPIQ------EKSVNNLD
HMGCS_PYRAE      -----------MSKVGIVSWGAYIPKYRIRTEEVARIWGDDPLRIVDVYLVDEKSVESLD
HMGCS_PYRIL      -----------MSRVGIVSWGAYIPKYRIRTEEVAKIWGDDPLRIVDLYLVDEKSVEGID
HMGCS_PYRAR      ------------MKVGIVSWGAYIPKYRIRTEEVARIWGDDPLRIVDVYLVDEKSVEGID
HMGCS_PYRCJ      -----------MSKLGVVSWGAYIPRYRVRTEEVSRIWGDDPLRIVDMYLVDEKSVEGID
HMGCS_PYRNV      -----------MGRVGVVSWGAYIPKYRIRTEEVARIWGDDPLRIVDLYLVDEKSVEGID
HMGCS_CALMQ      ------------MAVGIVGWGAYIPRYRIKTREIAEAWGDDALRIRDMYLVEEKAVGYID
HMGCS_SULAC      ------------MRSGIVGWGAYIPRYRINVNEIANLWGLESQVVKN-LGLSEKAVPDVD
HMGCS_SULTO      ------------MSSGIVGWGAYVPRYRLNVLEIAKLWGYDEGVVKS-LGLMEKAVPSHD
HMGCS_SULIY      ------------MLSGILGWGAYVPRYRIKVEDIAKMWGYDEGVVRS-LGLTEKSVPGHD
HMGCS_SULIN      ------------MLSGILGWGAYVPRYRIKVEDIAKMWGYDEGVVRS-LGLTEKSVPGHD
HMGCS_SULIL      ------------MLSGILGWGAYVPRYRIKVEDIAKMWGYDEGVVRS-LGLTEKSVPGHD
HMGCS_SULIM      ------------MLSGILGWGAYVPRYRIKVEDIAKMWGYDEGVVRS-LGLTEKSVPGHD
HMGCS_SULIA      ------------MLSGILGWGAYVPRYRIKVEDIAKMWGYDEGVVRS-LGLTEKSVPGHD
HMGCS_SULIK      ------------MLSGILGWGAYVPRYRIKVEDIAKMWGYDEGVVRS-LGLTEKSVPGHD
HMGCS_SACS2      ------------MLSGILGWGAYIPRYRIKVEDIAKMWGYDEAVVKS-LGLTEKSVPGHD
HMGCS_METS5      ------------MHTGIIGWGSYVPKYRIKVSDIASVWGKEEGVVKA-LGLTEKSVPAAD
HMGCS_AERPE      MPVDSLVGKTPESSAGIHGWGAYVPVYRIPTREIARVWGWPDHQWKA-LDVYEKAVGGVD
                                *:  :*  :* :*:   ::.  *.             .*:*    

HMGCS_METAC      EDAATIAVEAARYAMARSGVDPSRIGAVYTGSESHPYAVKPTSTIVAQAIGATPEMTAAD
HMGCS_METMA      EDAATIAVEAARNAMIRSGVDPSRIGAVYTGSESHPYAVKPTSTIVAQAIGATPQMTAAD
HMGCS_METBF      EDAATIAVEAARYAMTRSGVDPERIGAVYTGSESHPYAVKPTSTIVSQAIGATPNMTAAD
HMGCS_METBU      EDTATIAVEAARSAVLRNNIDAKRIGAVYTGSESHPYAVKPTSTIVAEAIEATPVLTAAD
HMGCS_METTP      EDTATIAVEAARNAISRANIDPHRIGAIYTGSESHPYAVKPTGTIVGEAIGCSHSHTVAD
HMGCS_METAR      EDTATIAVEAARNAIAR-GADPKKIGAIYVGSESHPYAVKPTATIVAAAIGAPNRMTAAD
HMGCS_THEAC      EDVATISVEAARNALKRKKIDPKEIGAIYVGSESHPYAVKPTATIVGSAIGVDFSLFAAD
HMGCS_THEVO      EDVATISVEAARNALKRKKINPKEIGAIYVGSESHPYAVKPTATIVGSAIGVDFSLFAAD
HMGCS_PICTO      EDVATISVEAARNALKRSNIDPNDIGAIYIGSESHPYAVKPTATIVAAAIGMPFRTFAAD
HMGCS_ARCFU      EDAATIAVEAAREAIRRAGINPEEIGAVFVGSESHPYAVKPTATIVGEALGVGNDYFAAD
HMGCS_METS3      EDTATIAVTAARYALARAQIDPQKIGAIYVGSESHPYAVKPSATIVAEAINATPDLTAAD
HMGCS_METST      EDTITISVEAARRALQRAEIDPQDIGAIYVGSESHPYAVKPTATIVADAIRASPNLTAAD
HMGCS_METTH      EDTATISVEAARNALRRSQIDPSEIGAVYVGSESHPYAVKPTATIVAEAVEATPEMTAAD
HMGCS_METM5      EDTATISVQAARRALSRAGINPKDIGAVYVGSESHPYAVKPTSGIVAEACGVSPDFTAAD
HMGCS_METM7      EDTATISVQAARRALSRAGINPKDIGAVYVGSESHPYAVKPTSGIVAEACGVSPDFTAAD
HMGCS_METM6      EDTATISVQAARRALSRAGINPKDIGAVYVGSESHPYAVKPTSGIVAEACGVSPDFTAAD
HMGCS_METMP      EDTATIAVQSARRALSRAGINPKDIGAVYVGSESHPYAVKPTSGIVAEACGVSPDFTAAD
HMGCS_METVS      EDSATIAVQAARRALSRSGINPKNIGAVYVGSESHPYAVKPTSGIVAEAVCTSPEVTAAD
HMGCS_METJA      EDTATIAVEAARNALKRAEIDPKDIGAVYVGSESHPYAVKPTATIVAEAIDATPDLTAAD
HMGCS_METKA      EDSATIAVEAAKNAVARAEIDPKDIGAIYVGSESPPYAVKPTATIVAAAIGATPDLTAAD
HMGCS_PYRAB      EDAVTIGIEAARNALKRAKIDPREIRAIWFGSESKPYAVKPSATIIAEAIGATPDLEAAD
HMGCS_PYRHO      EDAITIGIEAARNALKRAKIDPKDIRAIWFGSESKPYAVKPSSTVIAEAIGATPDLEAAD
HMGCS_PYRFU      EDAITIGIEAARNALKRAKIDPQKIRAIWFGTESKPYAVKPSATIIAEAIGATPDLEAAD
HMGCS_THEGJ      EDALTIGLEAARNALKRAGIDPKLIRAVWFGSESKPYAVKPTGTVIAEAIGATPDVSTAD
HMGCS_THEON      EDALTIGIEAARNALKRARIDPKLIRAVWFGSESKPYAVKPTGTVIAEAIGATPDVSTAD
HMGCS_THEKO      EDTITIGIEAARNALKRAQIDPKLIRAIWLGTESKPYAVKPSGTVIAEAIGATPDLDAAD
HMGCS_THESM      EDAITIGIEAARNALKRARINPREIRALWFGTESKPYAVKPSATVIAEAIGATPDLDAAD
HMGCS_PYRAE      EDAVTIAVEAARRALKRAGINPKRIGAVYVGTESKPYAVKPISSILVDALGLSNNVFAVD
HMGCS_PYRIL      EDAVTIAVEAAKRALKRARIDPKRIGAIYVGTESKPYAVKPISSILVDALGLSNNVFAVD
HMGCS_PYRAR      EDAVTIAVEAARRAIRRAGIDPKKIGAVYAGTESKPYAVKPISSILVDALGLSNNVFAVD
HMGCS_PYRCJ      EDAVTIAVEAARRAIRRGGIDPRKIGAVYVGTESKPYAVKPISSILIDALGLTNNVFAVD
HMGCS_PYRNV      EDAVTIAVEAARRALRRATLDPRRIGAVYVGTESKPYAVKPISSILIDALGLSNNVFAVD
HMGCS_CALMQ      EDPVTMAVEASRDALIRAGVKPSEVGAVFAGTESKPYAVKPISSILIDALGLNRQVYSVD
HMGCS_SULAC      EDSTTMAWESSKNALRRANIDPSQIGVVLFGSESKVYAVKPTATILIDALGVTNDSLGAD
HMGCS_SULTO      EDSTTMAWEAARNALMRAKIDPSEIKAVLFGSESKVYAVKPTSTIIIDSLGISHETLSAD
HMGCS_SULIY      EDSTTIAWESSINAIKRAQVDPSKIRLVLFGSESKVYAVKPTSTILIDALGINNYSATAD
HMGCS_SULIN      EDSTTIAWESSINAIKRAQVDPSKIRLVLFGSESKVYAVKPTSTILIDALGINNYSATAD
HMGCS_SULIL      EDSTTIAWESSINAIKRAQVDPSKIRLVLFGSESKVYAVKPTSTILIDALGINNYSATAD
HMGCS_SULIM      EDSTTIAWESSINAIKRAQVDPSKIRLVLFGSESKVYAVKPTSTILIDALGINNYSATAD
HMGCS_SULIA      EDSTTIAWESSINAIKRAQVDPSKIRLVLFGSESKVYAVKPTSTILIDALGINNYSATAD
HMGCS_SULIK      EDSTTIAWESSINAIKRAQVDPSKIRLVLFGSESKVYAVKPTSTILIDALGINNYSATAD
HMGCS_SACS2      EDSTTIAWESSINAIKRAQVDTSKIRLVLFGSESKVYAVKPTSTILIDALGINNYSATAD
HMGCS_METS5      EDSTTMAIEASRDALTRAMIDPREVEMALFGSESKVYAVKSTSAILIDALGLSKFSLTAD
HMGCS_AERPE      EDSTTMGVEAARNAIARARVDPASIGAVFFGSESKPYAVKPSATIIAEALGITPVTMASD
                 **  *:.  ::  *: *   ..  :     *:**  ****. . ::  :          *

HMGCS_METAC      FEFACKAGTAAVQACMGLVGSGMIDLGLAIGADVSQGAPSDALEYTAAAGGVACLIGRKE
HMGCS_METMA      FEFACKAGTAAVQACMGLVGSGMVDLGLAIGADVSQGAPSDALEYTAAAGGVACLIGRNE
HMGCS_METBF      FEFACKAGTAAVQACMGLVSSGMIDLGMAIGADVSQGAPGDALEYTAAAGGVACLIGKKE
HMGCS_METBU      FEFACKAGTAAMQACMGLVGSGMVDLGMAIGADVSQGAPGDALEYTAAAGGVSYIIGNKE
HMGCS_METTP      MEFACKAGTAALQACMGLVRSGMIDLGLAIGADVSQGAPGDALEYTAAAGGAAYVVG--A
HMGCS_METAR      FEFACKAGTAAIQTSMGVVASGLAETALAIGADTSQGAPGDALEYTAAAGGAAFVIS--K
HMGCS_THEAC      YEFACKAGTAGMQNVKAMVDSGMIKYGLAIGADTSQGAPGDALEYSASAGGTAFIIGK--
HMGCS_THEVO      YEFACKAGTAGMQNVKAMVDAGMIKYGLAIGADTSQGAPGDALEYSASAGGSAFIIGK--
HMGCS_PICTO      YEFACKAGTAAMQNIKAMVDSNMIKYGMAIGSDTSQGAPGDALEYTASAGGTAMVIGR--
HMGCS_ARCFU      LEFACKAGTAGMQICYSMVKAGMIKYGLAIGADTSQARPGDALEYAAAAGGAAFIIG---
HMGCS_METS3      LEFACKAGTAGIQMTMGLVDSDMIEYGLAIGADTSQGAPGDALEYTASAGGAAYIIG--K
HMGCS_METST      LEFACKAGTAGIQAAVGLVKSGMIKYGLAIGADTSQGAPGDALEYTASAGGAAYIIG--E
HMGCS_METTH      LEFACKAGTAGIQACMGLVDSGIIKYGLAVGADTAQGAPGDALEYTASAGGAAYVIG--G
HMGCS_METM5      LEFACKAGTAGMQMCMGLVGSEMMEYAMAVGADTAQGAPGDALEYTAAAGGAAYIIGAKK
HMGCS_METM7      LEFACKAGTAGIQMCMGLVGSDMMEYAMAVGADTAQGAPGDALEYTAAAGGAAYIIGAKK
HMGCS_METM6      LEFACKAGTAGIQMCMGLVGSGMMEYAMAVGADTAQGAPGDALEYTAAAGGAAYIIGAKK
HMGCS_METMP      LEFACKAGTAGIQMCMGLVGSEMMEYAMAVGADTAQGAPGDALEYTAAAGGAAFIIGAKK
HMGCS_METVS      LEFACKAGTAGIQMCMGLVSSGMMDYAMAVGVDTAQGAPGDALEYTAAAGGAAYIIGGKK
HMGCS_METJA      LEFACKAGTAGIQMCMGLVESGLIKYGLAIGADTAQGAPGDALEYTAAAGGAAYIIG--K
HMGCS_METKA      YEFACKAGTAAIQTCAGLVASGMIKYGLAIGADTAQGAPGDPLEYTAAAGGAAFVIG--R
HMGCS_PYRAB      FEFACKAGTEALQAAIGFVASGMAKYAMAIGADTAQGRPADHLEFTAGAGGAAFIVGEKS
HMGCS_PYRHO      FEFACKAGTEALQAAIGFVASGMAKYAMAIGADTAQGRPGDHLEFTAGAGGAAFIIGEKS
HMGCS_PYRFU      FEFACKAGTEALQAAIGFVGSGMAEYAMAIGADTAQGRPGDHLEFTAGAGGAAFIVGEKS
HMGCS_THEGJ      FEFACKAGTEALQTAIGFVGSEMADYAMAIGADTAQGRPGDHLEFTAGAGGAAFIVGPKS
HMGCS_THEON      FEFACKAGTEALQTAIGFVGSGMADYAMAIGADTAQGRPGDHLEFTAGAGGAAFIVGEKS
HMGCS_THEKO      FEFACKAGTEAIQAAIGFVGSGMADYAMAIGADTSQGRPGDHLEFTAAAGGAAYILAPKS
HMGCS_THESM      FEFACKAGTEALQAAIGFVGSGMAKYAMAIGADTSQGRPGDHLEFTASAGGAAYIVGEKT
HMGCS_PYRAE      MEFACKAGSEGLVAAIGLVESGRIEYGMTVGTDTSQGEPGEHLEYSASSGGASLIVG--R
HMGCS_PYRIL      MEFACKAGSEGLMAAVGLVESGRIEYGMTVGADTSQGEPGEHLEYSASSGGVALIVG--R
HMGCS_PYRAR      MEFACKAGSEGLVAAIGLVKAGQVEYGMTVGTDTSQGEPGEHLEYSASSGGVALIVG--R
HMGCS_PYRCJ      MEFACKAGSDGLVAAIGLVEAGRVEYGMTVGTDTSQGEPGEHLEYSASSGGVALIVG--K
HMGCS_PYRNV      MEFACKAGSEGLMAAVGLVESGKVEYGMTVGADTSQGEPGEHLEYSASSGGVALVVG--R
HMGCS_CALMQ      MEFACKAGSDAIINLMGLVKANSIKYGIAVGTDSSQGEPGEHLEYTVGTGAVAYVIG--S
HMGCS_SULAC      MEFACRGASAALRLVGGMVEASKIKYGLVIGSDTAQSNPGDVLELSSAAASVSYIVGPEN
HMGCS_SULTO      LEFACRAASVGLRLLSGMVEANRIKYGLVIGSDVAQSNPGDVLELSSAAASVAYIVGPAD
HMGCS_SULIY      MEFACRAASVGLRLASSFVLHNSDSYALVIGADTAQSNPGDVLELSSAAAGVAFVVGNVD
HMGCS_SULIN      MEFACRAASVGLRLASSFVLHNSDSYALVIGADTAQSNPGDVLELSSAAAGVAFVVGNVD
HMGCS_SULIL      MEFACRAASVGLRLASSFVLHNSDSYALVIGADTAQSNPGDVLELSSAAAGVAFVVGNVD
HMGCS_SULIM      MEFACRAASVGLRLASSFVLHNSDSYALVIGADTAQSNPGDVLELSSAAAGVAFVVGNVD
HMGCS_SULIA      MEFACRAASVGLRLASSFVLHNSDSYALVIGADTAQSNPGDVLELSSAAAGVAFVVGNVD
HMGCS_SULIK      MEFACRAASVGLRLASSFVLHNSDSYALVIGADTAQSNPGDVLELSSAAAGVAFVVGNVD
HMGCS_SACS2      MEFACRAASVGLRLASSFVLHNNDSYALVIGADTAQSNPGDVLELSSAAAGVAFVVGKTD
HMGCS_METS5      LEFACRAASAGLRMAFSMVESGQVSYSLVVGSDTAQSNPGDVLELSSAAAAVAFVVGRAE
HMGCS_AERPE      LEFACRAASEGMRASIGLVASGVVGYTLVVGSDTAQASPGDVLEFSASSGAAAFVIGPSK
                  ****:..: .:    ..*        :.:* * :*. *.: ** : .:.. : ::.   

HMGCS_METAC      SE-LAAIIEDTYSFTTDTPDFWRREGMPYPEHGGRFTGEPGYFKHVTNGAKGLLEKLGTK
HMGCS_METMA      SE-LAAIIEDTYSFTTDTPDFWRREGMPYPEHGGRFTGEPGYFKHVTNGAKGLLEKLGAK
HMGCS_METBF      SE-LAAIIEDTYSFTTDTPDFWRREGMPYPEHGGRFTGEPGYFKHVTNGAKGLLNKLGTK
HMGCS_METBU      SE-MIAVIEDTFSFTTDTPDFWRREGMPYPEHGGRFTGEPGYFKHVTGAANGLMEKMGTK
HMGCS_METTP      AD-LIAEIEGTYSFTTDTPDFWRREGIPYPEHGGRFTGEPAYFKHVMSAARGLMELLGKK
HMGCS_METAR      ND-HIAVINHTCSFTSDTPDFWRREGADYPRHGGRFTGDPGYFKHVLSASRMMLECQGTK
HMGCS_THEAC      DD-TIAEINSTLSVASDTPDFWRREGQPYPSHGERFTGEPAYFRHVITAAKMMMERMETQ
HMGCS_THEVO      DD-VIAEINSTLSVASDTPDFWRREGQPYPSHGERFTGEPAYFRHVVNAAKMMMERMETQ
HMGCS_PICTO      DN-VIAEINKTISVATDTPDFWRREGEPYPKHGERFTGEPGYFKHVIGAARDIMSELNTK
HMGCS_ARCFU      EN-PIAEVEATYSFTSDTPDFWRRDLQPYPSHGGRFTGLPAYFRHVISAAKGLMEKYGYK
HMGCS_METS3      DN-TLADIEETYSFTTDTPDFYRREGQDYPSHGGRFTGEPAYFKHVLSAAKGLFEKTDSK
HMGCS_METST      DN-TIADIEHTCSFTTDTPDFYRREGQAYPSHGGRFTGQPAYFKHVLGAANRMLEETGTT
HMGCS_METTH      KN-CLADIKETYSFTTDTPDFYRREGMPYPRHGGRFTGEPAYFKHVLGAARGMMEKTGLS
HMGCS_METM5      EE-FIAKFNGTYSYTTDTPDFWRREHEHYPKHGGRFTGEPAYFKHVLNGAKGMMAKMDTT
HMGCS_METM7      EE-LIAKFNGTYSYTTDTPDFWRREHEHYPKHGGRFTGEPAYFKHVLNGAKGMMAKMDTT
HMGCS_METM6      EE-LIAKFNGTYSYTTDTPDFWRREHEHYPKHGGRFTGEPAYFKHVLNGAKGMMAKMDTT
HMGCS_METMP      EE-FIAKFNGTYSYTTDTPDFWRREHEHYPKHGGRFTGEPAYFKHVLNGAKGMMEKMGTT
HMGCS_METVS      EE-LIAKFNGTYSYTTDTPDFWRREHEHYPKHGGRFTGEPAYFRHVLSAAKGMMEKMDTT
HMGCS_METJA      SN-VIAEFNGTYSYTTDTPDFWRREGKPYPRHGGRFTGEPAYFRHVINAAKGLMEKMGTK
HMGCS_METKA      KK-LVAEMEGTYSYTTDTPDFWRREGQPYPRHGGRFTGAPAYFKHIIRAARGLMEELDLS
HMGCS_PYRAB      SE-TLAYFEGSYSYVTDTPDFWRRQHEHYPRHGNRFTGEPAYFHHVITAAKTLMDELGLT
HMGCS_PYRHO      SE-TVAYFEGSYSYVTDTPDFWRRQHEHYPRHGNRFTGEPAYFHHVVTAAKTLMDELGLT
HMGCS_PYRFU      NE-SVAYFEGSYSYVTDTPDFWRRQHEHYPRHGNRFTGEPAYFHHIINAAKTLMEELGLK
HMGCS_THEGJ      SE-TVAYFEGSYSYVTDTPDFWRRQHEHYPRHGNRFTGEPAYFHHIINAAKTLMEELGLT
HMGCS_THEON      SE-TVAYFEGSYSYVTDTPDFWRRQHEHYPRHGNRFTGEPAYFHHIINAAKTLMEELGLT
HMGCS_THEKO      SE-TLAYFEASYSYVTDTPDFWRRQHEHYPRHGNRFTGEPAYFHQIINAAKTLMEELGYT
HMGCS_THESM      SD-TLAYFEGSYSYVTDTPDFWRRQHEHYPRHGNRFTGEPAYFHQIISAAKGLMEELDYS
HMGCS_PYRAE      DG-VVAELEAVYSYVSDTPDFWRREGSPYPMHGEGFTGEPAYFRHIIGAARGLMERYGYK
HMGCS_PYRIL      DG-IVAELEAVYSFVSDTPDFWRREGSPYPMHGEGFTGEPAYFRHIIGATRGLMEKYGYK
HMGCS_PYRAR      DG-VAAELEAVYSYVSDTPDFWRREGSPYPMHGEGFTGEPAYFRHIIGAAKGLMEKYGYK
HMGCS_PYRCJ      DG-VAAELEAMYAFVSDTPDFWRREGSPYPMHGEGFTGEPAYFRHVIGAAKGLMEKYGYK
HMGCS_PYRNV      EG-VAAELEAAYAYASDTPDFWRREGSPYPMHGEGFTGEPAYFRHVINAARGLMAAYGYK
HMGCS_CALMQ      SN-LAAEIKYTYPYASDTPDFWRRDSSPYPVHGEGFTGEPAYFKHIIGAAKGLMDELGMK
HMGCS_SULAC      E--AGAVIEAAVSYTSDTPDFWRRDGMPYPVHGEGFTGEPAYFDHILSAVNLLFRENGYK
HMGCS_SULTO      E--SSAIIEYATSYTTDMPDFWRRDGMPYPLHGEAFTGEPAYFAHIISAVQLLLKEGGYS
HMGCS_SULIY      EKHSAAVIEYSSSYTSDTPDFWRRDGTPYPVHGEGFTGEPAYFHHIISAVSDLLQNSGLK
HMGCS_SULIN      EKHSAAVIEYSSSYTSDTPDFWRRDGTPYPVHGEGFTGEPAYFHHIISAVSDLLQNSGLK
HMGCS_SULIL      EKHSAAVIEYSSSYTSDTPDFWRRDGTPYPVHGEGFTGEPAYFHHIISAVSDLLQNSGLK
HMGCS_SULIM      EKHSAAVIEYSSSYTSDTPDFWRRDGTPYPVHGEGFTGEPAYFHHIISAVSDLLQNSGLK
HMGCS_SULIA      EKHSAAVIEYSSSYTSDTPDFWRRDGTPYPVHGEGFTGEPAYFHHIISAVSDLLQNSGLK
HMGCS_SULIK      EKHSAAVIEYSSSYTSDTPDFWRRDGTPYPVHGEGFTGEPAYFHHIISAVSDLLQNSGLK
HMGCS_SACS2      EKHSAAVIEYSSSYTSDTPDFWRRDGTPYPVHGEGFTGEPAYFHHIISAVNDLLQNSGLK
HMGCS_METS5      E--ASAVVEASTSYVTDTPDFWRRDGMPYPLHGEAFTGEPAYFAHIYEAVNRLLQDTGLK
HMGCS_AERPE      G--AAAVFESSFTYVTDTPDFWRRGLKPYPSHGEGFTGEPAYFHHIESAVKGLFEKTGLS
                      * .:   . .:* ***:**    ** **  *** *.** ::  .   ::      

HMGCS_METAC      PEDYDYAVFHQPNGKFPSKAAKILGFTKAQITPGLVVPKIGNTYSGSCLMGIAATLDQAK
HMGCS_METMA      PEDYDYAVFHQPNGKFPSKAAKMLGFTKAQITPGLVVPKIGNTYSGSCLMGIAATLDQAK
HMGCS_METBF      PEDYDYAVFHQPNGKFPTKAAKTLGFTKAQIAPGLVVPKIGNTYSGSCLMGIAATLDQAK
HMGCS_METBU      PSDYDYAVFHQPNGKFPSRVAKMLGFTKEQIKPGLVVPWLGNTYSGSCMMGIAATLDQAK
HMGCS_METTP      PEDYDYAVFHQPNGKFPVRVAAKLGFTKEQIAPGLVVPHIGNTYSGSTLIGLAATLDQAE
HMGCS_METAR      PSDYNYAVFHQPNGKFPTRAALTLGFKKEQLSPGLTCPMMGNTYSGASMVGLSAVLDIAK
HMGCS_THEAC      PKDYDYVVFHQPNGKFPTRAAKMLGFEEKQYKDGLLTPYIGNTYSGSMMTGLSSILDVSK
HMGCS_THEVO      PKDYDYVVFHQPNGKFPTRAAKLLGFEEKQYKDGLITPYIGNTYSGSMMTGLSSILDVSK
HMGCS_PICTO      PDDYDYVVFHQPNGKFPTRAAKILGFREEQYREGLITPYIGNTYSGSTMTGLSAILDVSR
HMGCS_ARCFU      VEDFDYAVFHMPNAKFPVRAAKMLGFSMEHISQGLVVKAIGNTYSGSSLLGLAATLDVAE
HMGCS_METS3      PEDYDYACFHQPNGKFYLRAGKKLGFTSEQIKQGLLTPNIGNTYSGAVPLALSNILDVAE
HMGCS_METST      AKDYDYAVFHQPNGKFYIRVARKLGFTEDQYKQGLLTPNIGNTYSGATPLGLASILDIAK
HMGCS_METTH      ADDFDYAVFHQPNGKFYLKAARKLGFESEQVKPGLLTPVIGNTYSGATPVGLAATLDVAE
HMGCS_METM5      AKDYDYCVFHQPNGKFYISAAKQLGFTEEQYKYGLLTPYLGNTYSGAVPLGLSNILDHAK
HMGCS_METM7      AKDYDYCVFHQPNGKFYISAAKQLGFTEEQYKYGLLTPYLGNTYSGAVPLGLSNILDHAK
HMGCS_METM6      AKDYDYCVFHQPNGKFYITAAKQLGFTEEQYKYGLLTPYLGNTYSGAVPLGLSNILDHAK
HMGCS_METMP      SKDYDYCVFHQPNGKFYLTAAKKLGFTEEQYKYGLLTPYLGNTYSGAVPLGLSNILDHAK
HMGCS_METVS      TKDYDYCVFHQPNGKFYLSAAKQLGFNENQYRYGLLTPYLGNTYSGAVPLGLSNILDHSK
HMGCS_METJA      PEDYDYCVFHQPNGKFYIRVAKILGFKEEQYKIGLLTPYIGNTYSGAVPLGLSNVLDNCE
HMGCS_METKA      PEDFDYAVFHQPNGKFPRKVARSLGFEPEQVEPTIVVDRVGNTYSGSSLLGFTAALDRAE
HMGCS_PYRAB      PADFDYAVFHQPNVKFPLTAAKILGIPKEKVLPGLLTGKIGNTYSGATMVGISAVLDIAK
HMGCS_PYRHO      PEDFDYAVFHQPNVKFPLVAARMLGIPKEKVLPGLLSGRIGNTYSGATMVGISAVLDIAK
HMGCS_PYRFU      PSDFDYAVFHQPNVKFPLTVAKILGIPKEKVLPGLLTGRIGNTYSGATMVGVSAVLDIAK
HMGCS_THEGJ      VNDFDYAVFHQPNVKFPLTVAKILGIPKEKVLPGLLSGTIGNTYSGATMVGVSAVLDIAK
HMGCS_THEON      VNDFDYAVFHQPNVKFPLTVAKILGIPKEKVLPGLLTGIIGNTYSGATMVGVSAVLDIAK
HMGCS_THEKO      PNDFDYAVFHQPNVKFPLTAAKILGFPKEKVLPGLLSGIIGNTYSGATLVGVSAVLDIAK
HMGCS_THESM      PSDFDFAVFHQPNVKFPLTVAKILGIPKEKVLPGLLSGIIGNTYSGATLVGISAVLDIAK
HMGCS_PYRAE      PSDFAYVVFHQPNGRFPVRAASMLNIPMEKVKPGIVVTHIGNTYNASALMGFAKVLDIAK
HMGCS_PYRIL      PSDFTYAVFHQPNGRFPVRVASMLNIPIEKVKPGIVVTHIGNTYNASALMGFAKILDMAK
HMGCS_PYRAR      PSDFAYVVFHQPNGRFPVRAASMLNIPMEKIKPGIVVTHIGNTYNASALMGFAKVLDVAK
HMGCS_PYRCJ      PSDFTYVVFHQPNGRFPVRAASMLNIPLDKVKPGIVVTHIGNTYNASALMGFAKVLDIAK
HMGCS_PYRNV      PSDFAYAVFHQPNGRFPVRAASTLNIPMEKVKPGIVVTHIGNTYNASALMGFAKVLDQAK
HMGCS_CALMQ      PNDFDYAVFHQPNARFPVRVAQMLGFPLEKVKPGIVVDLIGNTYNASALLGLAKVLEEAK
HMGCS_SULAC      ISDFDYFVFHQPNGKFPLQVARKLEISMDKVKDGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_SULTO      ISDFDYFVFHQPNGKFPLQVAKKLGVPLEKVKEGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_SULIY      ISDFDYFVFHQPNGKFPIQVAKKLGVQLEKVKQGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_SULIN      ISDFDYFVFHQPNGKFPIQVAKKLGVQLEKVKQGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_SULIL      ISDFDYFVFHQPNGKFPIQVAKKLGVQLEKVKQGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_SULIM      ISDFDYFVFHQPNGKFPIQVAKKLGVPLEKVKQGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_SULIA      ISDFDYFVFHQPNGKFPIQVAKKLGVPLEKVKQGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_SULIK      ISDFDYFVFHQPNGKFPIQVAKKLGVPLEKVKQGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_SACS2      ISDFDYFVFHQPNGKFPIQVAKKLGVPLEKVKQGLVSPYIGNPYNASALLGLAKVLDIAK
HMGCS_METS5      VSDFDYFVFHQPNGKFPFQMAKKLGVPLEKVKQGMVSTLIGNPYNASALLGFARVLDVAK
HMGCS_AERPE      PGDFDYAIFHQPNGKFPVKVAKKLGFTMEQVKPGLVTPFIGNTYNASALLGLVKVLDVAK
                   *: :  ** ** :*    .  * .   :    :    :**.*..:   ..   *: ..

HMGCS_METAC      PGDRIFATAFGSGAGSDAFSITVTDRIEE-IRNRAPKVSELIKDPVYIDYARYARHKGKI
HMGCS_METMA      PGDRIFATAFGSGAGSDAFSITVTDRIEE-IRNRAPTVSELIKDPVYIDYARYARHKGKI
HMGCS_METBF      PGDRIFATAFGSGAGSDAFSITVTDRIEE-IRNRAPTVSELIKDPIYIDYARYAKHKGKI
HMGCS_METBU      PGDRIFATAFGSGAGGDAFSFRVTDKIDE-VRDAAPKVLDLLKDPVYMDYAMYAKHKGKI
HMGCS_METTP      PGESIFVTSFGSGAGSDAFSIRVTERIND-IRDRAPGVRDYIAIAEYIDYARYAKHKGKL
HMGCS_METAR      PGERIFVTSFGSGAGSDSFDITVTDRITE-VQDLAPKTWDYIKKAKYLDYASYARHKGKI
HMGCS_THEAC      PGDHILAVSFGSGAGSDAFDITVTDRIEEMDRNRAPTIKKMLENVKWVDYAIYAKYKKKI
HMGCS_THEVO      PGDHILAVSFGSGAGSDAFDITVTDRIEEMDRNKAPTIKKMLEKIKWVDYAIYAKYKKKI
HMGCS_PICTO      PGDRILAVSFGSGAGSDAFDITVTDNILDYHRENAPGVRKMMESTEYIDYAVYSKFRKIL
HMGCS_ARCFU      PDERILLVSFGSGAGSDAFAIRVTDAIENYPRE--PKVWEKIERKAYVDYAIYLKHRRKI
HMGCS_METS3      PGDKIFVVSYGSGAGSDGFTLTVNEEIKE-KRDLAPKTQDIIDRKQYVDYAVYAKFKGKI
HMGCS_METST      PGDKIFAVSYGSGAGSDAFKITVNDRIEE-VRNNAKTLEEIQSKITYVDYATYAKFKGKI
HMGCS_METTH      PGARILAVSYGSGAGSDAFIIEVNDLIEE-RRDLAPSVAEIIKNKRYVDYALYAKFKGKL
HMGCS_METM5      ADDRIFVVSYGSGAGSDAFDITVSDRISE-VVDKEITTEKLLESKKYVDYAVYLKYRGKI
HMGCS_METM7      ADDRIFVVSYGSGAGSDAFDITVTDRISE-VVDKAITTEKLLESKKYVDYAVYLKYRGKI
HMGCS_METM6      ADDRIFVVSYGSGAGSDAFDITVTDRISE-VVDKEITTEKLLESKKYVDYAVYLKYRGKI
HMGCS_METMP      ADDRIFVVSYGSGAGSDAFDITVTDRISE-VVDKEITTEKLLEQKKYVDYAVYLKYRGKI
HMGCS_METVS      TGDRIFVVSYGSGAGSDAFDITVTDRISE-VINKAVTTEELLSRKKYIDYAVYLKYRGKI
HMGCS_METJA      GGERILAVSYGSGAGSDAFDITVTDRINK-VKDKAPKTAYYLERKEYIDYAIYAKFRKKI
HMGCS_METKA      PGDRILVVSYGSGAGSDAFSFVVTERIEE-VREKAPLLEEYLEDRVYVTYGEYAKMKKKL
HMGCS_PYRAB      PGDRILWVSFGSGAGSDAFSIVVQDAIEE-KRDLAPKVEDYVKRRKVIDYALYAKARRKY
HMGCS_PYRHO      PGDRILWVSFGSGAGSDAFSIVVQDAIEE-KRNLAPKVEDYIKRRKVIDYALYAKARRKY
HMGCS_PYRFU      PGDRILWVSFGSGAGSNAFSIVVQDAIEE-KRDLAPKVEDYVKRRKVIDYALYAKARRKY
HMGCS_THEGJ      PGDRILWVSFGSGAGSDAFSVVVQDAIEE-KRNLAPKVKDYVERKKYIDYALYAKARRKY
HMGCS_THEON      PGDRILWVSFGSGAGSDAFSIVVQDAIEE-KRDLAPKTMDYVNRKKYIDYALYAKARRKY
HMGCS_THEKO      PGDRILWVSFGSGAGSDAFSLVVQDAIEE-KRDLAPKTMDYVNRKKYIDYALYAKHRGKY
HMGCS_THESM      PGDRILWVSFGSGAGSDAFSLIVQDAIEE-KRELAPKTMDYVNRKKYLDYALYAKHRGKY
HMGCS_PYRAE      PGDKILLVPFGSGAGSNAFVFTVTELITERQKSGVPTVEDMLRDKIYIDYAQYLKMRKMI
HMGCS_PYRIL      PGDKILLVPFGSGAGSNAYVFTVTDTILERQKTDVPTVEQMLRDKIYIDYAQYLKMRKMI
HMGCS_PYRAR      PGDKILLVPFGSGAGSNAFVFTVTDVVQERQKTGVPTVEDMLRDKIYVDYAQYLKMRKMI
HMGCS_PYRCJ      PGDKILLVPFGSGAGSNAFVFTVTDVVKDRQKMGVPTVEEMLQDKILVDYAQYLKMRKMI
HMGCS_PYRNV      PGDKILVVTFGSGAGSNAYVFSATDLIKERQNAAVPTVEAMLRDKIYVDYAQYLKMRKMI
HMGCS_CALMQ      PGAKIIVVTFGSGAGSNAFYIETTDQLPGKVKL-ARTIGEMLEDKVYIDYSLYLKYRKII
HMGCS_SULAC      PGQRILVAPFGSGAGSDAFSILVTDKILE-KQKLAPTVNYYIERKVLVSYSTYAKTTGKY
HMGCS_SULTO      PGQRILVAPFGSGAGSDAFSILVTDKIEE-RQKLAPRVEDYINNKKVISYSVYAKTTNKY
HMGCS_SULIY      PGERILVAPFGSGAGSDAFSILVSEGILE-KQKLAKTVEYYINNKKLVSYAEYAKYTNKI
HMGCS_SULIN      PGERILVAPFGSGAGSDAFSILVSEGILE-KQKLAKTVEYYINNKKLVSYAEYAKYTNKI
HMGCS_SULIL      PGERILVAPFGSGAGSDAFSILVSEGILE-KQKLAKTVEYYINNKKLVSYAEYAKYTNKI
HMGCS_SULIM      PGERILVAPFGSGAGSDAFSILVSEGILE-KQKLAKTVEYYINNKKLVSYAEYAKYTNKI
HMGCS_SULIA      PGERILVAPFGSGAGSDAFSILVSEGILE-KQKLAKTVEYYINNKKLVSYAEYAKYTNKI
HMGCS_SULIK      PGERILVAPFGSGAGSDAFSILVSEGILE-KQKLAKTVEYYINNKKLVSYAEYAKYTNKI
HMGCS_SACS2      PGERILVAPFGSGAGSDAFSILVSEGILA-KQKLAKTVEYYINNKKLVSYAEYAKYTNKI
HMGCS_METS5      PGQRVLVAPFGSGAGSDAYSFVITDKILE-RQKLAHTTDYYIQRKKLVDYASYAKTTHKF
HMGCS_AERPE      PGDRILVAPFGSGAGSDAYSLIVTDAIEE-AKPLAQPLEYYLKRRIEIDYGVYAKIRGKL
                  .  :: ..:*****.:.: .   : :                    : *. * :     

HMGCS_METAC      RLA----
HMGCS_METMA      RLA----
HMGCS_METBF      RRS----
HMGCS_METBU      RLA----
HMGCS_METTP      RL-----
HMGCS_METAR      NTDN---
HMGCS_THEAC      IVGDGIE
HMGCS_THEVO      VLGDGIE
HMGCS_PICTO      VFGDNLE
HMGCS_ARCFU      KA-----
HMGCS_METS3      KM-----
HMGCS_METST      KMN----
HMGCS_METTH      RMA----
HMGCS_METM5      RM-----
HMGCS_METM7      RM-----
HMGCS_METM6      RM-----
HMGCS_METMP      RM-----
HMGCS_METVS      RM-----
HMGCS_METJA      KM-----
HMGCS_METKA      KF-----
HMGCS_PYRAB      IL-----
HMGCS_PYRHO      II-----
HMGCS_PYRFU      IL-----
HMGCS_THEGJ      IL-----
HMGCS_THEON      IM-----
HMGCS_THEKO      IL-----
HMGCS_THESM      IL-----
HMGCS_PYRAE      KLFE---
HMGCS_PYRIL      KLFE---
HMGCS_PYRAR      KLFD---
HMGCS_PYRCJ      KLFE---
HMGCS_PYRNV      KLFEY--
HMGCS_CALMQ      KMIHG--
HMGCS_SULAC      KVYE---
HMGCS_SULTO      KVYE---
HMGCS_SULIY      KVYE---
HMGCS_SULIN      KVYE---
HMGCS_SULIL      KVYE---
HMGCS_SULIM      KVYE---
HMGCS_SULIA      KVYE---
HMGCS_SULIK      KVYE---
HMGCS_SACS2      KVYE---
HMGCS_METS5      KVYD---
HMGCS_AERPE      VVRKL--