CLUSTAL format seed alignment for MF_01480

_____________________________________________________________________________

Features found in the protein:_____________________________________________________________________________

Q5L8F8_BACFN          --------------------------MKRILGLDLGTNSIGWALVNEAEN---KDERSSI
F9YQX1_CAPCC          --------------------------MKHILGLDLGTNSIGWAVVKEAQN---DNEQSEI
F0P0P2_WEEVC          --------------------------MKTILGLDLGTNSIGWALVEQDFE----NKQGLI
R7D4J2_9BACE          --------------------------MKHILGLDLGTNSIGWAVIRAHQDADGHTTLQDI
G8XA12_FLACA          --------------------------MTKILGLDLGTNSIGWAIRDTENE-----GINQI
G2Z1C1_FLABF          --------------------------MAKILGLDLGTNSIGWAVVEREN------IDFSL
B8I085_RUMCH          --------------------------MKYTLGLDVGIASVGWAVIDKDNNK--------I
N9W911_9CLOT          ----------------------MDKELNYAIGLDIGITSVGWAVVNLDLNR--------I
B1GZM3_ENDTX          -------------------------MKKRILGLDIGIASVGWALVEFDDEFQDNKKKGTI
CAS9_PASMU            ---------------------MQTTNLSYILGLDLGIASVGWAVVEINENED----PIGL
F9QBH3_9PAST          ---------------------MENKNLHYILGLDLGIASVGWAVVEIDKEEN----PLCL
A9HKP2_GLUDA          -------------------MGENMIDESLTFGIDLGIGSCGWAVLRRPSAFGR---KGVI
I3TWJ0_TISMK          -----------------------MINERLTFGIDLGIGSCGWAVLRHADAAGE---PGVI
Q20XX4_RHOPB          ---------------------MSERVVRRILGIDLGIASCGWGVV---DISGA---GGGI
I7GTK8_9HELI          ---------------------------MKIYSFDIGVASIGWAFIE----------NEVL
D3UFL8_HELM1          --------------------------MIRTLGIDIGIASIGWAVIEGEYTDKG-LENKEI
A8LN05_DINSH          ----------------------------MRLGLDIGTSSIGWWLYETDGAGSDARITGVV
A1WH93_VEREI          ----------------------MNKAVAYRLALDLGSTSLGWAIFRLNEAREP---TAII
J6LE60_9RHOB          --------------------------MGIRFAFDLGTNSIGWAVWRTGPGVFGEDTAASL
CAS9A_STRTD           -------------------------MSDLVLGLDIGIGSVGVGILNKVTG--------EI
A8AY02_STRGC          -------------------------MNGLVLGLDIGIASVGVGILEKDTG--------KI
C4ZA16_AGARV          ----------------MNYTEKEKLFMKYILALDIGIASVGWAILDKESE--------TV
Q73QW6_TREDE          ---------------------MKKEIKDYFLGLDVGTGSVGWAVTDTDYKLLKAN-----
B0RZQ7_FINM2          ----------------------MKSEKKYYIGLDVGTNSVGWAVTDEFYNILRAK-----
G4Q6A5_ACIIR          ------------------------MGKMYYLGLDIGTNSVGYAVTDPSYHLLKFK-----
R5GJ26_9FIRM          ------------------------MNNEYFVGFDIGTNSVGAAVTDEKYHVLKFK-----
CAS9_STRP1            ------------------------MDKKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLG
CAS9_STRMU            ------------------------MKKPYSIGLDIGTNSVGWAVVTDDYKVPAKKMKVLG
CAS9B_STRTD           ------------------------MTKPYSIGLDIGTNSVGWAVTTDNYKVPSKKMKVLG
CAS9_LISIN            ------------------------MKKPYTIGLDIGTNSVGWAVLTDQYDLVKRKMKIAG
E6LI02_ENTI1          ------------------------MKNDYTIGLDIGTNSVGYSVVTDDYKVISKKMNVFG
A0A142LIG4_9PROT      -------------------MNDKKNLGPLTFGFDIGIASVGWAVLSPTR----------I
Q7MRD3_WOLSU          -------------------------MIERILGVDLGISSLGWAIVEYDKDDE---AANRI
U2LZE9_TRELE          ---------------------MNNKNQKYRLGLDLGTNSIGWCIYSLDGSNKP----DAL
E1QW44_OLSUV          -------------------MNLRNTTDEYNIGLDMGTNSVGWAVTDKAGAIAHFK-----
A0A1B3SLT6_9MOLU      -------------------------MKKVNIGLDIGIASVGWSIYDIENKK--------I
R7EW40_9BACT          ---------------------------MKVLGLDLGTASIGWAVIDTNVENPN---DIQL
Q2RX87_RHORT          ----------------------MRPIEPWILGLDIGTDSLGWAVFSCEEKGPP--TAKEL
I0AP30_IGNAJ          ------------------------MEFKKVLGLDIGTNSIGCALLSLPKSIQDYGKGGRL
D1AUW6_STRM9          --------------------------MKYILGLDLGVASIGWAVTEINEKGEP----VGL
B2KB46_ELUMP          MQKNINTKQNHIYIKQAQKIKEKLGDKPYRIGLDLGVGSIGFAIVSMEENDGNVLLPKEI
F0RSV0_SPHGB          ----MSKKVSRRYEEQAQEICQRLGSRPYSIGLDLGVGSIGVAVAAYDPIKKQ---PSDL
E9S7M7_RUMAL          -------------------------MGNYYLGLDVGIGSIGWAVINIEKKR--------I
Q4A5I2_MYCS5          --------MLNNVQNLWKYLLLLIFDKKIIFLFKIKVILIRRYMENNNKEKIVIGFDLGV
Q7NAI2_MYCGA          ------------------MNNSIKSKPEVTIGLDLGVGSVGWAIVDNETNI--------I
Q6KIQ7_MESM1          --------------MYFYKNKENKLNKKVVLGLDLGIASVGWCLTDISQKEDN---KFPI
E6WZS9_NITSE          --------------------------MKKILGVDLGITSFGYAILQETGKDLY-----RC
K1LM04_9FLAO          --------------------------MKHILGLDLGTNSIGWALIERNIEEKY----GKI
                                                      ..:        .                

Q5L8F8_BACFN          VKLGVRVNPLTVDELTNFEKGKS-----ITTNADRTLKRGMRRNLQRYKLRRETLTEVLK
F9YQX1_CAPCC          VDVGVRVNPLTTDEKTNFEKGKP-----ISTNADRTLKRSARRNLQRYKLRRKELIELLK
F0P0P2_WEEVC          LGMGSRIIPMDAGIIGKFAEGSS-----ISQTAERTGYRSIRRLRERHLLRRERLHRVLN
R7D4J2_9BACE          LAAGSRIIPMDAATLTDFDKGNA-----RSGTAERTSFRSMRRRRERQLLRRERLHRVLM
G8XA12_FLACA          LDKGARIFSEGVKS----ENGKE-----ISRAAERTAYRSARKIKYRRKLRKYETLKVLS
G2Z1C1_FLABF          IDKGVRIFSEGVKS----EKGIE-----SSRAAERTGYRSARKIKYRRKLRKYETLKVLS
B8I085_RUMCH          IDLGVRCFDKAEESKTGESLAT-----------ARRIARGMRRRISRRSQRLRLVKKLFV
N9W911_9CLOT          EDLGVRIFNAAENPKDGASLAL-----------PRRLARGRRRLLRRRAYRLKRVKRLIV
B1GZM3_ENDTX          IKSGVRIFTRAETPKERESLAK-----------PRREARSQRRRIRRRVERLNSIRELFV
CAS9_PASMU            IDVGVRIFERAEVPKTGESLAL-----------SRRLARSTRRLIRRRAHRLLLAKRFLK
F9QBH3_9PAST          IDVGVRTFERAEVPKTGESLAL-----------SRRLARSARRLTQRRVARLKKAKRLLK
A9HKP2_GLUDA          EGMGSWCFDVPETSKERTPTNQ-----------IRRSNRLLRRVIRRRRNRMAAIRRLLH
I3TWJ0_TISMK          EGLGSWCFDVPETSKERIPTNQ-----------VRRSNRLLRRVIRRRRNRMAEIRRLFH
Q20XX4_RHOPB          IATGVRCFDAPLIDKTGEPKSA-----------TRRTARGQRRIVRRRRQRMNGVRRLLC
I7GTK8_9HELI          QDCGIRIFTKAENPKNGASLAL-----------PRREARGVRKRLARRRGRLNTIKQLLC
D3UFL8_HELM1          VASGVRVFTKAENPKNKESLAL-----------PRTLARSARRRNARKKGRIQQVKHYLS
A8LN05_DINSH          DG-GVRIFSDGRDPKSGASLAV-----------DRRAARAMRRRRDRYLRRRATLMKVLA
A1WH93_VEREI          RA-GVRIFSDGRNANS-EPLAV-----------HRRVARAMRRRRDRLLKRKKRMHDQLV
J6LE60_9RHOB          DGSGVLIFKDGRNPKDGQSLAT-----------MRRVPRQSRKRRDRFVLRRRDLLAALR
CAS9A_STRTD           IHKNSRIFPAAQAENNLVRRTN----------------RQGRRLARRKKHRRVRLNRLFE
A8AY02_STRGC          IHASSRLFPAATADNNVERRSN----------------RQGRRLNRRKKHRSVRLQDLFE
C4ZA16_AGARV          IEAGSNIFPEASAADNQLRRDM----------------RGAKRNNRRLKTRINDFIKLWE
Q73QW6_TREDE          -------RKDLWGMRCFETAETA---------EVRRLHRGARRRIERRKKRIKLLQELFS
B0RZQ7_FINM2          -------GKDLWGVRLFEKADTA---------ANTRIFRSGRRRNDRKGMRLQILREIFE
G4Q6A5_ACIIR          -------GEPMWGAHVFAAGNQS---------AERRSFRTSRRRLDRRQQRVKLVQEIFA
R5GJ26_9FIRM          -------GNAMWTSAVFESAQQS---------ADRRLNRTARRRLDRSQQRRDLLQELIA
CAS9_STRP1            NTDRHSIKKNLIGALLFDSGETA---------EATRLKRTARRRYTRRKNRICYLQEIFS
CAS9_STRMU            NTDKSHIEKNLLGALLFDSGNTA---------EDRRLKRTARRRYTRRRNRILYLQEIFS
CAS9B_STRTD           NTSKKYIKKNLLGVLLFDSGITA---------EGRRLKRTARRRYTRRRNRILYLQEIFS
CAS9_LISIN            DSEKKQIKKNFWGVRLFDEGQTA---------ADRRMARTARRRIERRRNRISYLQGIFA
E6LI02_ENTI1          NTEKKSIKKNFWGVRLFESGQTA---------QEARMKRTSRRRIARRKNRICYLQEIFQ
A0A142LIG4_9PROT      VDLGVRCFDKAETAKEGESLNLA-----------RRSARLMRRRLRRRAWRLIKLARLLK
Q7MRD3_WOLSU          IDCGVRLFTAAETPKKKESPNK-----------ARREARGIRRVLNRRRVRMNMIKKLFL
U2LZE9_TRELE          IDMGVRIFSDGRDPKTKKPLAVE-----------RRTARGLRRILHRRKQRRKQMFRLLQ
E1QW44_OLSUV          -------GKPTLGSRLFDAAQTA---------AGARIHRSQRRRYVRRRWRLDLLQSLFQ
A0A1B3SLT6_9MOLU      VKAGSRLFSEANAGTSKTSTTSD-----------RREQRGRRRNLRRALRRRMDLIKLFV
R7EW40_9BACT          LGNGSRIIQYDNNEASDFSAGKG-----ETPCTQRTFRRTARKCLDRYQQRRDKLRAFLV
Q2RX87_RHORT          LGGGVRLFDSGRDAKDHTSRQAE-----------RGAFRRARRQTRTWPWRRDRLIALFQ
I0AP30_IGNAJ          EWLTSRVIPLDADYMKAFIDGKNGLPQVITPAGKRRQKRGSRRLKHRYKLRRSRLIRVFK
D1AUW6_STRM9          IDANSVIFKPLDNDKGKLYNVER------------RDKRGSRRILRRKKHRVERTKMLLV
B2KB46_ELUMP          IMVGSRIFKASAGAADRKLSRGQ-----------RNNHRHTRERMRYLWKVLAEQKLALP
F0RSV0_SPHGB          VFVSSRIFIPSTGAAE------------------RRQKRGQRNSLRHRANRLKFLWKLLA
E9S7M7_RUMAL          EDFNVRIFKSGEIQEKNRNSRAS---------QQCRRSRGLRRLYRRKSHRKLRLKNYLS
Q4A5I2_MYCS5          ASVGWSIVNAETKEVIDLGVRLFSE---PEKADYRRAKRTTRRLLRRKKFKREKFHKLIL
Q7NAI2_MYCGA          HHLGSRLFSQAKTAED------------------RRSFRGVRRLIRRRKYKLKRFVNLIW
Q6KIQ7_MESM1          ILHGVRLFETVDDSDDKLLNETR------------RKKRGQRRRNRRLFTRKRDFIKYLI
E6WZS9_NITSE          LDNSVVMRNNPYDEKSGESSQS-----------IRSTQKSMRRLIEKRKKRIRCVAQTME
K1LM04_9FLAO          IGMGSRIVPMGAELSKFEQGQAQ------TKNADRRTNRGARRLNKRYKQRRNKLIYILQ
                                                            :  :.                 

Q5L8F8_BACFN          EHKLITEDTILSENGNRTTFETYRLRAKAVTEEISL-----------EEFARVLLMINKK
F9YQX1_CAPCC          EHQLISTDTILTENGKGTTFQTLELRAKSAKEKISL-----------EELARVFLTINKK
F0P0P2_WEEVC          ILKFLPEHYAAEIDFEKRFGQFLAETEPKLAWKKN------------AEGKFEFLFQRSF
R7D4J2_9BACE          LLGFLPQHYANSL---TRYGEFADNRECKLPWVKDE-----------SDGKYHFLFQDAF
G8XA12_FLACA          INGMCPLSVEEVEQWKKSGFKEYPLNPEFLDWLRTNE----------DKNINPYLFRDKA
G2Z1C1_FLABF          LNRMCPLSIEEVEEWKKSGFKDYPLNPEFLKWLSTDE----------ESNVNPYFFRDRA
B8I085_RUMCH          QY-EIIKDSSEFNRIF------DTSR----------------------------------
N9W911_9CLOT          EK-NILTQNQLDNLFK------DNN-----------------------------------
B1GZM3_ENDTX          KN-GVVEEWSVSKKNPNN---IYITL----------------------------------
CAS9_PASMU            RE-GILSTIDLEKGLPN-------------------------------------------
F9QBH3_9PAST          LE-NILLSTD--ERLPH-------------------------------------------
A9HKP2_GLUDA          AA-GLLPSTDSDALKRP-------------------------------------------
I3TWJ0_TISMK          AQ-GLLPSADEDALKRP-------------------------------------------
Q20XX4_RHOPB          EF-GLLPDPRPDALNQAMRRISTASA----------------------------------
I7GTK8_9HELI          KEFGLQLEDYLSNDGELPKAYTASKA----------------------------------
D3UFL8_HELM1          KALGLDLECFVQGE---KLATLFQTS----------------------------------
A8LN05_DINSH          ETGLMPADPAEAKALEA-------------------------------------------
A1WH93_VEREI          QHGFFPAEVAERKELER-------------------------------------------
J6LE60_9RHOB          KAGLFPVDVEEGRRLAA-------------------------------------------
CAS9A_STRTD           ESGLITDFTKISINLNP-------------------------------------------
A8AY02_STRGC          GYGLLTDFSKVSMNLNP-------------------------------------------
C4ZA16_AGARV          NNNLSIPQFKSTEIVG--------------------------------------------
Q73QW6_TREDE          QEIAKTDEGFFQRMKESPFYAEDKTILQENTLFNDK------------------------
B0RZQ7_FINM2          DEIKKVDKDFYDRLDESKFWAEDKKVSGKYSLFNDK------------------------
G4Q6A5_ACIIR          PVISPIDPRFFIRLHESALWRDDVAETDKHIFFNDP------------------------
R5GJ26_9FIRM          PAITPVDPRFFDRIRESALWAEDKTTGSRFTYFSDE------------------------
CAS9_STRP1            NEMAKVDDSFFHRLEESFLVEEDK--KHERHPIFGN------------------------
CAS9_STRMU            EEMGKVDDSFFHRLEDSFLVTEDK--RGERHPIFGN------------------------
CAS9B_STRTD           TEMATLDDAFFQRLDDSFLVPDDK--RDSKYPIFGN------------------------
CAS9_LISIN            EEMSKTDANFFCRLSDSFYVDNEK--RNSRHPFFAT------------------------
E6LI02_ENTI1          PEMNHLDNNFFYRLNESFLVADDA--KYDKHPIFGT------------------------
A0A142LIG4_9PROT      HEGLIADTKTFIQPSAS-------------------------------------------
Q7MRD3_WOLSU          RAGLIQDVDLDGEGGMFYSK----------------------------------------
U2LZE9_TRELE          EQGLMPNDAVQATALKS-------------------------------------------
E1QW44_OLSUV          DEVSKVDSEFFCRLRQSRLYVGDREKGHADYTWPIFN----------DS-----------
A0A1B3SLT6_9MOLU      DFKYINSQQDFYQLDFN-------------------------------------------
R7EW40_9BACT          ETGMIKPDEKFPPLNPL-------------------------------------------
Q2RX87_RHORT          AAGLTPPAAETRQIALA-------------------------------------------
I0AP30_IGNAJ          TLNWLPEDFPLDNPKRIKETISTEGKFSFRISDYVPISDESYREFYREFGYPENEIEQVI
D1AUW6_STRM9          NSSFLTNEEIDNLYVGK-------------------------------------------
B2KB46_ELUMP          VPADLDRKENSSEGETSAKRFLGDV-----------------------------------
F0RSV0_SPHGB          ERNLMLSYSEQDVPDPARLRFEDAV-----------------------------------
E9S7M7_RUMAL          IIGLTTSEKIDYYYETAD------------------------------------------
Q4A5I2_MYCS5          KNAEIFGLQSRNEILNVYKDQSSK------------------------------------
Q7NAI2_MYCGA          KYNSYFGFKNKEDILNNYQEQQK-------------------------------------
Q6KIQ7_MESM1          DNNIIELEFDKNPKILVRNFIEKYINPFSKNLELKYK-----------------------
E6WZS9_NITSE          RYGILDYSETMKINDPKN------------------------------------------
K1LM04_9FLAO          KLDMLPSQIKLKEDFSDPNKIDKITILPISKKQEQ-------------------------
                                                                                  

Q5L8F8_BACFN          RGYKSSRKAKGVE-------EGTLIDGMDIARELYNNNLTPG--ELCLQLLDAGKKFLPD
F9YQX1_CAPCC          RGYKSSRKAKNED-------EGQLIDGMEIAKRLYEENLTTG--QLSLQLLKEGKKSLPD
F0P0P2_WEEVC          DEMVADFKANGQD-----IKIPYDWTIYYLRKKALTQKISPQ--ELAWIILNFNQK--RG
R7D4J2_9BACE          HEMCEDFRQLAPQWVADGKKVPYDWTLYYLRCKALSRKISKE--ELAWILLSFNQK--RG
G8XA12_FLACA          SKQKVTLFELGRALYHIAQRRGFLSNRLDQSAEGVFEEHNPQ--IQNLIEDLDSSNTILN
G2Z1C1_FLABF          SKHKVSLFELGRAFYHIAQRRGFLSNRLDQSAEGILEEHCPK--IEAIVEDLISIDEIST
B8I085_RUMCH          ---------------------DGWKDPWELRYNALSRILKPY--ELVQVLTHITKR--RG
N9W911_9CLOT          -----------------------ICSVWEARVKGLDSKLTNE--EWAKILINLCKR--RG
B1GZM3_ENDTX          ---------------------NQIKTPWQLRMESLDRKLTNE--QFAVVLTHLAKH--RG
CAS9_PASMU            -------------------------QAWELRVAGLERRLSAI--EWGAVLLHLIKH--RG
F9QBH3_9PAST          -------------------------QVWQLRVEGLDRKLKRQ--EWAAVLLHLIKH--RG
A9HKP2_GLUDA          -----------------------GHDPWELRARGLDKPLKPV--EFAVVLGHIAKR--RG
I3TWJ0_TISMK          -----------------------RLDPWELRARGLDQCLSAE--EFAVALGHIARH--RG
Q20XX4_RHOPB          ---------------------AAQVTPWTLRAAAHQRLLSNE--ELAVVLGHIARH--RG
I7GTK8_9HELI          ---------------------NPLKSPYELRTLALSQKLDSK--DLVRVILHIAKH--RG
D3UFL8_HELM1          ---------------------KDFLSPWELRERALYRVLDKE--ELARVILHIAKR--RG
A8LN05_DINSH          ------------------------LDPFALRAAGLDEPLPLP--HLGRALFHLNQR--RG
A1WH93_VEREI          ------------------------LNPYQLRAKGLHEALTPG--EFARALFHINQR--RG
J6LE60_9RHOB          ------------------------TDPYHLRAKALDESLTPH--EMGRVIFHLNQR--RG
CAS9A_STRTD           ---------------------------YQLRVKGLTDELSNE--ELFIALKNMVKHRGIS
A8AY02_STRGC          ---------------------------YQLRVQGMENQLTNE--ELFVALKNIVKRRGIS
C4ZA16_AGARV          -----------------------------LKVRAITEEITLD--ELYLILYSYLKHRGIS
Q73QW6_TREDE          -------------DFADKTYHKAYPTINHLIKAWIENKVKPDP-RLLYLACHNIIKKRGH
B0RZQ7_FINM2          -------------NFSDKQYFEKFPTIFHLRKYLMEEHGKVDI-RYYFLAINQMMKRRGH
G4Q6A5_ACIIR          -------------TYTDKEYYSDYPTIHHLIVDLMESSEKHDP-RLVYLAVAWLVAHRGH
R5GJ26_9FIRM          -------------GYTDKQYHKEYPTIHHLICSLMNDPAPHDP-RLVYIACSYMLTHRGH
CAS9_STRP1            -------------IVDEVAYHEKYPTIYHLRKKLVDSTDKADL-RLIYLALAHMIKFRGH
CAS9_STRMU            -------------LEEEVKYHENFPTIYHLRQYLADNPEKVDL-RLVYLALAHIIKFRGH
CAS9B_STRTD           -------------LVEEKAYHDEFPTIYHLRKYLADSTKKADL-RLVYLALAHMIKYRGH
CAS9_LISIN            -------------IEEEVEYHKNYPTIYHLREELVNSSEKADL-RLVYLALAHIIKYRGN
E6LI02_ENTI1          -------------LDEEIHFHEQFPTIYHLRKYLADGDEKADL-RLVYLAIAHIIKFRGN
A0A142LIG4_9PROT      -----------------------HASPWQLRKDGLDRALSPE--EWARVLYHLCKHRGFH
Q7MRD3_WOLSU          ---------------------ANRADVWELRHDGLYRLLKGD--ELARVLIHIAKHRGYK
U2LZE9_TRELE          ------------------------LNPYELRVRALDAKLEPY--ELGRVLFNLSVR--RG
E1QW44_OLSUV          -------------DFNEVDYYKRFPTIYHLRKWLMETDEKADI-RLIYLATHNIVKHRGN
A0A1B3SLT6_9MOLU      ------------------------FNYLEKRNQALNEQISRD--ELLVLLFNFIKKRGSF
R7EW40_9BACT          -------------------------ETWKLRSDAATPGTKLSTSEIARVLLHINQR--RG
Q2RX87_RHORT          -----------------------------LRREAVSRPLAPDALWAALLHLAHHRGFRSN
I0AP30_IGNAJ          EEINFRRKTKGKNKNPMIKLLPEDWVVYYLRKKALIKPTTKE--ELIRIIYLFNQR--RG
D1AUW6_STRM9          -----------------------LDNIYEVRLKGLKEQLSKN--EIARLMIYYCKN--RG
B2KB46_ELUMP          ----------------------LQKDIYELRVKSLDERLSLQ--ELGYVLYHIAGHRGSS
F0RSV0_SPHGB          ----------------------VRANPYELRLKGLNEQLTLS--ELGYALYHIANHRGSS
E9S7M7_RUMAL          ------------------------NNVIQLRNKGLSEKLTPEEIAACLIHICNNRGYKDF
Q4A5I2_MYCS5          -----------------------YRNILKLKINALKEEIKPS--ELVWILRDYLQNRGYF
Q7NAI2_MYCGA          ----------------------LHNTVLNLKLEALNAKIDPK--ALSWILHDYLKNRGHF
Q6KIQ7_MESM1          ------------------SVTNLPIGFHNLRKAAINEKYKLDKSELIVLLYFYLSLRGAF
E6WZS9_NITSE          ---------------------NPIKNRWQLRAVDAWKRPLSPQ-ELFAIFAHMAKHRGYK
K1LM04_9FLAO          ---------------------LTAFDLVSLRVKALTEKVGLEDLGKIIYKYNQLRGYAGG
                                                                                  

Q5L8F8_BACFN          FYRSDLQNELDRIWEKQKEYYPEILTDVLKEELRGKKRDAVWAICAKYFVWKENYTEWNK
F9YQX1_CAPCC          YYRSDLQFELDKVWNFQKQFHSHILTDEFYAQLKGKGQ---RATSALFLAKYQIYTAENK
F0P0P2_WEEVC          YYQLRGEEEEENPNKKVEFYSLKIVDVVADEQPNKKGDTWYSLHLENGWVYRRSSKIPLY
R7D4J2_9BACE          YYQARDEEDEVTTNKLEEYYAGKVVRVDDTGERKGK-NVYYDITLENGWVYRYAARI-YP
G8XA12_FLACA          ELKEYYINLGIIDETEKSGFKKDLDEGEKKLKSLYNSLVAITKKNANDIETCKQELIARL
G2Z1C1_FLABF          NITDYFFETGILDSNEKNGYAKDLDEGDKKLVSLYKSLLAILKKNESDFENCKSEIIERL
B8I085_RUMCH          FKSNRKEDL-ST--TKEGVVITSI------------------------------------
N9W911_9CLOT          FKSNRKNEA-KE--KEAGAIISSI------------------------------------
B1GZM3_ENDTX          YKSLRKD-------DKAGKVLEAI------------------------------------
CAS9_PASMU            YLSKRKNES-QTNNKELGALLSGV------------------------------------
F9QBH3_9PAST          YLSQRKNES-KSENKELGALLSGV------------------------------------
A9HKP2_GLUDA          FKSAAKRKA-TNISSDDKKMLTAL------------------------------------
I3TWJ0_TISMK          FRSSAKRKA-ANTSGEDSKMLSAL------------------------------------
Q20XX4_RHOPB          FRSNAKNEAGANAADETSKMKKAM------------------------------------
I7GTK8_9HELI          YGNKHAKDSK---DTESGKVKKAI------------------------------------
D3UFL8_HELM1          YDDITYGVE----DNDSGKIKKAI------------------------------------
A8LN05_DINSH          FKSNRKTDR---GDNESGKIKDAT------------------------------------
A1WH93_VEREI          FKSNRKTDR---KDNDSGALKQAI------------------------------------
J6LE60_9RHOB          FRSNRKADR---QDREKGKIAEGS------------------------------------
CAS9A_STRTD           YLDDASDDGNSSVGDYAQIVKENSKQ----------------------------------
A8AY02_STRGC          YLDDASEDGGTVSSDYGKAVEENRKL----------------------------------
C4ZA16_AGARV          YLEDALDDTVSGSSAYANGLKLNAKE----------------------------------
Q73QW6_TREDE          FLFEGDFDSEN-QFDTSIQALFEYLREDME---VDIDAD-SQKVKEILKDSSLKN--SEK
B0RZQ7_FINM2          FLIDGQISHVT-DDKPLKEQLILLINDLLK---IELEEELMDSIFEILADVNEKR--TDK
G4Q6A5_ACIIR          FLNEVDKDNIG-DVLSFDAFYPEFLAFLSD---NGVS-PWVCESKALQATLLSRNSVNDK
R5GJ26_9FIRM          FLNEADKEKID-DVLDIRRVFNELCSWFTS---YGIEVPFSCFPEEFGNVLTANRGVQDR
CAS9_STRP1            FLIEGDLNPDNSDVDKLFIQLVQTYNQLFE------ENPINASGVDAKAILSARLSKSRR
CAS9_STRMU            FLIEGKFDTRNNDVQRLFQEFLAVYDNTFE------NSSLQEQNVQVEEILTDKISKSAK
CAS9B_STRTD           FLIEGEFNSKNNDIQKNFQDFLDTYNAIFE------SDLSLENSKQLEEIVKDKISKLEK
CAS9_LISIN            FLIEGALDTQNTSVDGIYKQFIQTYNQVFASGIEDGSLKKLEDNKDVAKILVEKVTRKEK
E6LI02_ENTI1          FLIEGELNTENNSVIELSKVFVQLYNQTLS---ELEGFQFIDESIDFSEVLTQQLSKSER
A0A142LIG4_9PROT      WVSRAEARKADGDTKGEGGKVKQGL-----------------------------------
Q7MRD3_WOLSU          FIGDDEADEESGKVKKAGVVLRQN------------------------------------
U2LZE9_TRELE          FKSNRKEAVQEKEKDSQNDTKSQNEK----------------------------------
E1QW44_OLSUV          FLRENNKSLSSRDANPAQAVKSLRLALNDWCS----ERDYECAWKGEEDDGAIDEAILNV
A0A1B3SLT6_9MOLU      NYKDDILEMKEEKKEEIDISKITDKK----------------------------------
R7EW40_9BACT          YRHAKSDMSDSKQTEYVARV----------------------------------------
Q2RX87_RHORT          RIDKRERAAAKALAKAKPAKATAKAT----------------------------------
I0AP30_IGNAJ          FKSSRKDLTETAILDYDEFAKRLAEKEKYSAENYETKFVSITKVKEVVELKTDGRKGKKR
D1AUW6_STRM9          FKSNRKTEDLEILKSLGEKISEKDSD----------------------------------
B2KB46_ELUMP          AIRTFENDSEEAQKENTENKKIAG------------------------------------
F0RSV0_SPHGB          SVRTFLDEEKSSDDKKLEEQQ---------------------------------------
E9S7M7_RUMAL          YEVNVEDIEDPDERNEYKEEHDSI------------------------------------
Q4A5I2_MYCS5          YKNEKLTDEFVSNSFPSKKLHEHYEKYGFF------------------------------
Q7NAI2_MYCGA          YEDNRDFNVYPTEELANYFDEFGY------------------------------------
Q6KIQ7_MESM1          FDNPEDTKSKEMNKNEIEIFDKNES-----------------------------------
E6WZS9_NITSE          SIATEDLIYELELELGLNDPEKESEK----------------------------------
K1LM04_9FLAO          SLEPEKEDIFDEEQSKDKKNKSFIAFSKIVFLG-------------EPQEEIFKNKKLNR
                                                                                  

Q5L8F8_BACFN          EKGKTEQQEREHKLEGIYSKRKRDEAKRENLQWRVNGLKEKLSLEQLVI----------V
F9YQX1_CAPCC          --------------------GSREDKKLQAYQWRVDALSKELTREQLAF----------V
F0P0P2_WEEVC          DWKDKVRDFIVTTDINEDGSEKLDKDGEVKRSFRAPKEDDWTLIKKKTE----------Q
R7D4J2_9BACE          DWVGQVKEFIVTTTLNPDGTPKTDKAGEVKRSFRMPKDDDWTLIKKKKE----------R
G8XA12_FLACA          NKKEDLGKVKGKIKDISQAMLDRNFKTLGQYFFSLYNKERIRNQYTSRE----------E
G2Z1C1_FLABF          NKKDVLGKVKGKIKDISQAMLDGNYKTLGQYFYSLYSKEKIRNQYTSRE----------E
B8I085_RUMCH          -----------------------KNNSEMLRTKNYRTIGEMIFM----------------
N9W911_9CLOT          -----------------------NKNIEIMKENNSRTIGECIYK----------------
B1GZM3_ENDTX          -----------------------SQNKKRLNDSDYRTLGEMFCK----------------
CAS9_PASMU            -----------------------AQNHQLLQSDDYRTPAELALK----------------
F9QBH3_9PAST          -----------------------ASNHELLQQTTYRTPAELAVK----------------
A9HKP2_GLUDA          -----------------------EATRERL--GRYRTVGEMFAR----------------
I3TWJ0_TISMK          -----------------------LVTRERT--ARYRTVGEMFAR----------------
Q20XX4_RHOPB          -----------------------EATREGL--AKYHAFGDMIAN----------------
I7GTK8_9HELI          -----------------------EFNRKTLAEKGYRSVGEYLYR----------------
D3UFL8_HELM1          -----------------------AENSKRIKEEQCKTIGEMMYK----------------
A8LN05_DINSH          -----------------------ARLDMEMMANGARTYGEFLHKRRQK-----------A
A1WH93_VEREI          -----------------------SELRKRIQDSDCATAGEWFWKERMQQ----------K
J6LE60_9RHOB          -----------------------KRLAETLAATNCRTLGEFLW-----------------
CAS9A_STRTD           ---------------------LETKTPGQIQLERYQTYGQLRGDFTVE-----------K
A8AY02_STRGC          ---------------------LAEKTPGQIQLERFEKYGQLRGDFTVE-----------E
C4ZA16_AGARV          ---------------------LETHYPCEIQQERLNTIGKYRGQSQIIN----------E
Q73QW6_TREDE          QSRLNKILGLKPSDKQK-------KAITNLISGNKINFADLYDNP----D--------LK
B0RZQ7_FINM2          KNNLKELIKGQDFNKQEGNI---LNSIFESIVTGKAKIKNIISDEDILEK--------IK
G4Q6A5_ACIIR          YKALKSLIFGSQKPEDNFDANISEDGLIQLLAGKKVKVNKLFPQES--------------
R5GJ26_9FIRM          TRAFYDLLFAGKKPKPSEDDQVDIDVLIKLISGGKIELSKLFLNEEY------------S
CAS9_STRP1            LENLIAQLPGEKK-------NGLFGNLIALSLGLTPNFKSNFDLAE--------------
CAS9_STRMU            KDRVLKLFPNEKS-------NGRFAEFLKLIVGNQADFKKHFELEE--------------
CAS9B_STRTD           KDRILKLFPGEKN-------SGIFSEFLKLIVGNQADFRKCFNLDE--------------
CAS9_LISIN            LERILKLYPGEKS-------AGMFAQFISLIVGSKGNFQKPFDLIE--------------
E6LI02_ENTI1          ADNVLKLFPDEKG-------TGIFAQFIKLIVGNQGNFKKVFQLEE--------------
A0A142LIG4_9PROT      -----------------------ASTTKLMNDKSYRTAAEMVLA----------------
Q7MRD3_WOLSU          -----------------------------FEAAGCRTVGEWLWR----------------
U2LZE9_TRELE          ----------------------CERLAKAIKDSGYRTLGEFLWKHKNTE-----------
E1QW44_OLSUV          LADGEKGRSDQAKEIAKLTGVDCGDAKQSKQCNEAIAKAIVGLKVEMKNI--------FG
A0A1B3SLT6_9MOLU      -----------------------DKLPVEIQLDNYKLYGKYRGINTEDS-----------
R7EW40_9BACT          ------------------------NNRFAEIKNLNQTVGQFFYTKL--------------
Q2RX87_RHORT          -----------------------APAKEADDEAGFWEGAEAALRQRMAA-----------
I0AP30_IGNAJ          FKVILEDSRIEPYEIERKEKPDWEGKEYTFLVTQKLEKGKFKQNKPDLPKEEDWALCTTA
D1AUW6_STRM9          -----------------------EKKLKPIIAKNTELIESKGLTPIEVI-----------
B2KB46_ELUMP          ------------------------NIKRLMAKKNYRTYGEYLYKEFFEN-----------
F0RSV0_SPHGB          -----------------------AMTEQLAKEKGISTFIEVLTA----------------
E9S7M7_RUMAL          -----------------------VLISNLMNEGGYCTPAEMICNCREFD-----------
Q4A5I2_MYCS5          ----------------------RGSVKLDNKLDNKKDKAKEKDEEEESD-----------
Q7NAI2_MYCGA          -----------------------YKGIIDSKNDDDDKLEEGLTK----------------
Q6KIQ7_MESM1          --------------------IKNAEFPIDKIIEFYKISGKIRSTI---------------
E6WZS9_NITSE          -----------------------KADERRQVYNALRHLEELRKKYGGET-----------
K1LM04_9FLAO          RAIIVETEEGNFEGSTFLENIKVGDSLELLINISASKSGDTITIKLPNKTNWRKKMENIE
                                                                                  

Q5L8F8_BACFN          FQEMNTQINNSSGYLGAISDRSKELYFNKQTVGQYQMEMLDK----NPNASLR------N
F9YQX1_CAPCC          ITEINNNLNNSSGYLGAISDRSKELYFNNETVGEYLWKQIAA----NPHTSLK------N
F0P0P2_WEEVC          EIEQFNQTVGSYIYEALLDNPTQKIRGKLVRTIERKFYKSELKKILEKQIELQ------P
R7D4J2_9BACE          DIDRSQETIGQYIYHALLKDPSQKIRGKLIGTVERKYYKDELRRILDRQIQFH------P
G8XA12_FLACA          HYLEEFIIICQTQGIEGINTNEKLPEKKFTGLAKDLYRAIFFQRPLKSQKGLI------G
G2Z1C1_FLABF          HYLSEFITICKVQGIDQINEEEKINEKKFDGLAKDLYKAIFFQRPLKSQKGLI------G
B8I085_RUMCH          ----------ETPENS----NKRNKVDEYIHTIAREDLLNEIKYIFSIQRKLG------S
N9W911_9CLOT          ----------RVKESDDAYKALRNKYGEYTMCTSRGIIREEINILFEKQRSFG------A
B1GZM3_ENDTX          ----------NESYKE----HKRNKGGEYINSVARELIEEEVEKIFVKQREKG------N
CAS9_PASMU            ----------KFAKEEG---HIRNQRGAYTHTFNRLDLLAELNLLFAQQHQFG------N
F9QBH3_9PAST          ----------KFEVEEG---HIRNQQGAYTHTFSRLDLLAEMELLFSRQQHFG------N
A9HKP2_GLUDA          ----------DPDFASR----RRNREGKYDRTTARDDLEHEVHALFAAQRRLG------Q
I3TWJ0_TISMK          ----------DPEYSAR----RRNRDGIFDRTVARDDLIHEVGKLFEAQRARG------S
Q20XX4_RHOPB          ----------DPKFANR----KRNRDKDYSHTAKRSDLEDEVRAILRAQLRFG------S
I7GTK8_9HELI          ----------EFFQQSR---ISQNNGATEFINVRNKAGNYEHCVAQDMLKEEL------E
D3UFL8_HELM1          ----------LYFQKSL---NVRNKKESYNRCVGRSELREELKTIFQIQQELK------S
A8LN05_DINSH          TDPRHVPSVRTRLSIANRGGPDGKEEAGYDFYPDRRHLEEEFHKLWAAQGAHH------P
A1WH93_VEREI          PEGVRGQWVRARYRKTPSTTDEGKKRIGYDLYVDRAMVEQEFDALWAAQAALQ------P
J6LE60_9RHOB          --SRHRGTPRTRSPTRIRMEGEG-AKALYAFYPTREMVRAEFERLWTAQSRFA------P
CAS9A_STRTD           DGKKHRLINVFPTSAYRSEALRILQTQQEFNPQITDEFINRYLEILTGKRKYY------H
A8AY02_STRGC          NGEKHRLINVFSTSAYRKEAERILRKQQEFNSKITDEFIEDYLIILTGKRKYY------H
C4ZA16_AGARV          NGEVLDLSNVFTIGAYRKEIQRVFEIQKKYHPELTDEFCDGYMLIFNRKRKYY------E
Q73QW6_TREDE          DAEKNSISFSKDDFDALSDDLASILGDSF-ELLLKAKAVYNCSVLSKVIGDEQ-----YL
B0RZQ7_FINM2          EDNKEDFVLTGDSYEENLQYFEEVLQENI-TLFNTLKSTYDFLILQSILKGKS-----TL
G4Q6A5_ACIIR          --NDASFTLNDKE-DAIEEILGTLTPDEC-EWIAHIRRLFDWAIMKHALKDGR-----TI
R5GJ26_9FIRM          ELENNKIQLSDAGFDEKEPELRSELGDDF-GLVAAAKNIYDWSLLTGVLGECK-----SI
CAS9_STRP1            ---DAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPL
CAS9_STRMU            ---KAPLQFSKDTYEEELEVLLAQIGDNYAELFLSAKKLYDSILLSGILTVTDVGTKAPL
CAS9B_STRTD           ---KASLHFSKESYDEDLETLLGYIGDDYSDVFLKAKKLYDAILLSGFLTVTDNETEAPL
CAS9_LISIN            ---KSDIECAKDSYEEDLESLLALIGDEYAELFVAAKNAYSAVVLSSIITVAETETNAKL
E6LI02_ENTI1          ---DQKLQLSTDDYEENIENLLAIIGDEYGDIFVAAQNLYQAILLAGILTSTE-KTRAKL
A0A142LIG4_9PROT      ----------------EFPSAQRNKRGEYTKALSRELLDNELKQLFERQREYGNPHADTN
Q7MRD3_WOLSU          --------------ERGANGKKRNKHGDYEISIHRDLLVEEVEAIFVAQQEMR------S
U2LZE9_TRELE          ---------TPQMENDAGDIGMRFVPGRSNYYPTRRMYIEEFDAIRKVQELYY-------
E1QW44_OLSUV          EFPAEKTSYIYLSSDEDVEAVRESCPDDSGELFQALCKLYSAYILQELLSYAD-PSGQTI
A0A1B3SLT6_9MOLU      ----------LIAHEWYKREIEKILETQVKFNVVDKDFCEKYLELFDRKRQYFD------
R7EW40_9BACT          ----------KASECTTVRGKKHYTYRIKEEVFPRNAYAEEFDSIISAQGEFY------P
Q2RX87_RHORT          -----SGAPTVGALLADDLDRGQPVRMRYNQSDRDGVVAPTRALIAEELAEIVAR---QS
I0AP30_IGNAJ          LDNRMGSKHPGEFFFDELLKAFKEKRGYKIRQYPVNRWRYKKELEFIWTKQCQLNPELNN
D1AUW6_STRM9          ---------YMIRENDNSILGFKNKEGNYKFGFKRNQVIDEVRKILGTQQILS-------
B2KB46_ELUMP          -------------KEKHKREKISNAANNHKFSPTRDLVIKEAEAILKKQAGKD----GFH
F0RSV0_SPHGB          ----------FNTNGLIGYRNSESVKSKGVPVPTRDIISNEIDVLLQTQKQFY------Q
E9S7M7_RUMAL          ------------EPNSVYRKFHNSAASKNHYLITRHMLVKEVDLILENQSKYY-------
Q4A5I2_MYCS5          -----AKKESEELIFSNKQWINEIVKVFENQSYLTESFKEEYLKLFNYVRPFN------K
Q7NAI2_MYCGA          ------------YKFSNQHWLEEVKKVLSNQTGLPEKFKEEYESLFSYVRNYS------E
Q6KIQ7_MESM1          --------NLKFGHQDYLKEIKQVFEKQNIDFMNYEKFAMEEKSFFSRIRNYS------E
E6WZS9_NITSE          ------IAQTIHRAVEAGDLRSYRNHDDYEKMIRREDIEEEIEKVLLRQAELG-----AL
K1LM04_9FLAO          NQLKEKSKEMGREFYISEFLLELLKENRWAKIRNNTILRARYESEFEAIWNEQVKHYPFL
                                                                                  

Q5L8F8_BACFN          MVFYRQDYLDEFNMLWEKQAVYHKE------LTEELKKEIRDIIIFYQRRLKSQKGLIGF
F9YQX1_CAPCC          QVFYRQDYLDEFEQIWKTQSAFYPEI-----LTDELKKELRDVVIFYQRKLKSQKSLVSF
F0P0P2_WEEVC          ELFTEDLYNACARELYRRNVAHQQQL-----SSRDFVYLFLNDIIFYQRPLRSQKSLISN
R7D4J2_9BACE          ELRDRELYYACLQELYPSNVAFRNTL-----VNRDFTYLFLDDILFYQRPLKSKKSQISD
G8XA12_FLACA          KCSFEKNKSRCAVSHPDYEEFRMWSY-----LNTIKIGTQSEKTLRFLTLEEKLKLVPKF
G2Z1C1_FLABF          KCSFEKSKSRCAISHPDFEEYRMWTY-----LNTIKIGTQSDKKLRFLTQDEKLKLVPKF
B8I085_RUMCH          PFVTEKLEHDFLNIWEFQRP--------------FASGDSILSKVGKCTLLKEEL-----
N9W911_9CLOT          EFASSEIEDMYLEIFDSQRP--------------YSDFDKLEKFVGYCTFEKGVK-----
B1GZM3_ENDTX          NFADVNTEREYLKIAFSQK-----------------PAGSISKMVGFCTFENGEK-----
CAS9_PASMU            PHCKEHIQQYMTELLMWQKP--------------ALSGEAILKMLGKCTHEKNEF-----
F9QBH3_9PAST          PFASEKLLENLTALLMWQKP--------------ALSGEAILKMLGKCTFE-DEY-----
A9HKP2_GLUDA          GFASPELEEAFTASAFHQRP--------------MQDSE---RLVGFCPFERTEK-----
I3TWJ0_TISMK          AFASPDLEADFNAIAFRQAE--------------MQDSE---RLVGNCPFERDEK-----
Q20XX4_RHOPB          AAATETLAQTFADVAFFQRP--------------LQDSE---DRVGDCPFEPGQK-----
I7GTK8_9HELI          SILNAQRQFGFSLKQDFESKLLTK-------IFEQRPLKSFADKVGNCCFIAGEK-----
D3UFL8_HELM1          PWVNEELIYKLLGNPDAQSKQEREGL-----IFYQRPLKGFGDKIGKCSHIKKGEN----
A8LN05_DINSH          EL-TETLRDLLFEKIFFQRP-------------LKEPEVGLCLFSGHHGVPPKDP-----
A1WH93_VEREI          GLFTEAARAELKDTLLYQRD-------------LRPVK------PGRCTLLPAEE-----
J6LE60_9RHOB          DLLTPERHEEIAGILFRQRD-------------LAPPK------IGCCTFEPSER-----
CAS9A_STRTD           GPGNEKSRTDYGRYRTSGE----------------TLDNIFGILIGKCTFYPDEF-----
A8AY02_STRGC          GPGNEKSRTDYGRFRTDGT----------------TLDNIFGILIGKCTFYTEEY-----
C4ZA16_AGARV          GPGNEKSRTDYGRFTTKLDANGNY----------ITEDNIFEKLIGKCSVYPDEL-----
Q73QW6_TREDE          SFAKVKIYEKHKTDLTKLKNVIKKHF-----PKDYKKVFGYNKNEKNNNNYSGYVGVCKT
B0RZQ7_FINM2          SDAQVERYDEHKKDLEILKKVIKKYD-----EDG--KLFKQVFKEDNGNGYVSYIGYYLN
G4Q6A5_ACIIR          SESKVKLYEQHHHDLTQLKYFVKTYL-----AKEYDDIFRNVDSETTKNYVAYSYHVKEV
R5GJ26_9FIRM          SEAKVKTYEKHSEDLAALRRVVRKYH-----PDKYKEIFKKYVVGNYTSYSGNVKSAGKI
CAS9_STRP1            SASMIKRYDEHHQDLTLLKALVRQQL-----PEKYKEIFFDQSKNGYAGYIDGGASQEE-
CAS9_STRMU            SASMIQRYNEHQMDLAQLKQFIRQKL-----SDKYNEVFSDVSKDGYAGYIDGKTNQEA-
CAS9B_STRTD           SSAMIKRYNEHKEDLALLKEYIRNIS-----LKTYNEVFKDDTKNGYAGYIDGKTNQED-
CAS9_LISIN            SASMIERFDTHEEDLGELKAFIKLHL-----PKHYEEIFSNTEKHGYAGYIDGKTKQAD-
E6LI02_ENTI1          SASMIQRYEEHAKDLKLLKRFVKEHI-----PDKYAEIFNDATKNGYAGYIDGKTKEEE-
A0A142LIG4_9PROT      LEAKIRGSGDHKSGLFWEQK-------------PALSGNDLLKMLGKCTFEKQEY-----
Q7MRD3_WOLSU          TIATDALKAAYREIAFFVRP-----------------MQRIEKMVGHCTYFPEER-----
U2LZE9_TRELE          ---RDVNWDALHEKLFYQRP-------------------LRVQERGKCRYMPDKE-----
E1QW44_OLSUV          SANMVAKYKQYGRDLRLLKELTRTYA-----PQKYDLFFRGETYAGSSDYVVDEARGYTR
A0A1B3SLT6_9MOLU      GPGWTTSSKTQKSKYGWKDE-----------------KEFFERLSGYDTYDSKEK-----
R7EW40_9BACT          QLLTTENVAELRNLIFYQRPLKSCKH-----LVSYCDFEKRVFKNSAGKEVDGGP-----
Q2RX87_RHORT          SAYPGLDWPAVTRLVLDQRP-------------------LRSKGAGPCAFLPGED-----
I0AP30_IGNAJ          LNINKEILRKLATVLYPSQSKFFGPK-----IKEFENSDVLHIISEDIIYYQRDLKSQKS
D1AUW6_STRM9          ----KEIVDEYIDILSSQRDFSDGP------GGDSKYKIDYTKLAGKCKYTGEVR-----
B2KB46_ELUMP          KELTEEYIEKLTKAIGYESE-------------------KLIPESGFCPYLKDEK-----
F0RSV0_SPHGB          EILSDEYCDRIVSAILFENE-------------------KIVPEAGCCPYFPDEK-----
E9S7M7_RUMAL          GILDDKTIAKIKDIIFAQRDFEIGPGK----NERFRRFTGYLDSIGKCQFFKDQE-----
Q4A5I2_MYCS5          GPGSKNSRTAYGVFSTDIDPETNKFK---------DYSNIWDKTIGKCSLFEEEI-----
Q7NAI2_MYCGA          GPGSINSVSPYGIYHLDEKEGK----------VVQKYNNIWDKTIGKCSIFPDEY-----
Q6KIQ7_MESM1          GPGNEKSFSKYGLYANENGNPELIINEKGQKIYTKIFKTLWESKIGKCSYDKKLY-----
E6WZS9_NITSE          GLPEEQVSELIDELKACITD--------------QEMPTIDESLFGKCTFYKDEL-----
K1LM04_9FLAO          ENLDKKTLIEIVSFIFPGEKESQKKYRELGLEKGLKYIIKNQVVFYQRELKDQSHLISDC
                                                                                  

Q5L8F8_BACFN          CEFESR-------------------------QIEVDID-GKKKIKTVGNRVISRSSPLFQ
F9YQX1_CAPCC          CEFENK-------------------------EIEIKKEDGTSTKKVIGLKVAPKSSPLFQ
F0P0P2_WEEVC          CSLEFR-------------------------TIKDKD----GNGQIIYLKAIPKSNPYYQ
R7D4J2_9BACE          CPYEEH-------------------------FYTDKET---GERISVPVKCIAVSHPLYQ
G8XA12_FLACA          YRKSDF-------------------------NFEVLAKELVEKGASFGYYKSSKKNEFFY
G2Z1C1_FLABF          YRKNDF-------------------------NFDVLAKELIEKGSSFGFYKSSKKNDFFY
B8I085_RUMCH          --------------------------------------------------RAPTSCYTSE
N9W911_9CLOT          --------------------------------------------------RAPKKCISAE
B1GZM3_ENDTX          --------------------------------------------------RAPRDSYSAE
CAS9_PASMU            --------------------------------------------------KAAKHTYSAE
F9QBH3_9PAST          --------------------------------------------------KAAKNTYTAE
A9HKP2_GLUDA          --------------------------------------------------RAAKLTPSFE
I3TWJ0_TISMK          --------------------------------------------------RAARWAPSFE
Q20XX4_RHOPB          --------------------------------------------------RAARRAPSFE
I7GTK8_9HELI          --------------------------------------------------RAPKDSPSAI
D3UFL8_HELM1          -----------------------------------------------SPYRACKHAPSAE
A8LN05_DINSH          --------------------------------------------------RLPKAHPLTQ
A1WH93_VEREI          --------------------------------------------------RAPLALPSTQ
J6LE60_9RHOB          --------------------------------------------------RLPRALPSVE
CAS9A_STRTD           --------------------------------------------------RAAKASYTAQ
A8AY02_STRGC          --------------------------------------------------RASKASYTAQ
C4ZA16_AGARV          --------------------------------------------------RAAAASYTAQ
Q73QW6_TREDE          KSKKLIINNSVNQEDFYKFLKTILSAKSEIKE--VNDILTEIETGTFLPKQISKSNAEIP
B0RZQ7_FINM2          KNKKITAKKKISNIEFTKYVKGILEKQCDCEDEDVKYLLGKIEQENFLLKQISSINSVIP
G4Q6A5_ACIIR          KGTLPKNKATQEEFCKYVLGKVKNIECSEADKVDFDEMIQRLTDNSFMPKQVSGENRVIP
R5GJ26_9FIRM          SETKLK-RCNQAEFCDYLKSKLKDVKPAPGDD-ECERVLKEISKHTFCPRQVTTDNRVIP
CAS9_STRP1            ---------------FYKFIKPILEKMD-----GTEELLVKLNREDLLRKQRTFDNGSIP
CAS9_STRMU            ---------------FYKYLKGLLNKIE-----GSGYFLDKIEREDFLRKQRTFDNGSIP
CAS9B_STRTD           ---------------FYVYLKKLLAEFE-----GADYFLEKIDREDFLRKQRTFDNGSIP
CAS9_LISIN            ---------------FYKYMKMTLENIE-----GADYFIAKIEKENFLRKQRTFDNGAIP
E6LI02_ENTI1          ---------------FYKYLKTTLVQKS-----GYQYFIEKIEQENFLRKQRIYDNGVIP
A0A142LIG4_9PROT      --------------------------------------------------RAPKASFTAE
Q7MRD3_WOLSU          --------------------------------------------------RAPKSAPTAE
U2LZE9_TRELE          --------------------------------------------------RTFKAMPCSQ
E1QW44_OLSUV          YNLGTTKANYDDFQKSVKELFKGTDALQ---DERYQEMMVAFGEQKFLRRLKTSDNGSIY
A0A1B3SLT6_9MOLU      --------------------------------------------------RAPKHSMTSY
R7EW40_9BACT          -------------------------------------------------KVTPKSSPLAQ
Q2RX87_RHORT          --------------------------------------------------RALRALPTVQ
I0AP30_IGNAJ          LISECRYE-----------------------------KRKGIDGEIYGLKCIPKSSPLYQ
D1AUW6_STRM9          ---------------------------------------------------AVKSAPSYE
B2KB46_ELUMP          --------------------------------------------------RLPASHKLNE
F0RSV0_SPHGB          --------------------------------------------------KLPRCHFLNE
E9S7M7_RUMAL          --------------------------------------------------RGSRFTVIAD
Q4A5I2_MYCS5          --------------------------------------------------RAPKNLPSAL
Q7NAI2_MYCGA          --------------------------------------------------RAPKNSPIAM
Q6KIQ7_MESM1          --------------------------------------------------RAPKNSFSAK
E6WZS9_NITSE          --------------------------------------------------AAPAYSYLYD
K1LM04_9FLAO          RYEPNE-------------------------------------------KAIAKSHPVFQ
                                                                                  

Q5L8F8_BACFN          EFKIWQILNNIEVTVVGK------------KRKRRKLKENYSALFEELNDAEQLELNGSR
F9YQX1_CAPCC          EFKIWQNLNNVLIRKKGS------------KTKKVD-KNQQAVLFEEEKTIFELDL----
F0P0P2_WEEVC          EFRVWQWLYNLKIFTKED--------DKDVTNQFINKVEDLEALFEFLMNQKEVNHT---
R7D4J2_9BACE          EYRLWQFIQNLRIYCREARIDGNLMIDWEVTNELLQTEEDKTALFDWLNDKESVKQP---
G8XA12_FLACA          WFNYKPTDSVSACVVSASLENAIGKDWKIKTFEYQTRNTEKNEVTKSVDYKDLWHLLSVA
G2Z1C1_FLABF          WFNYKPTDTVAACQVAASLKNAIGEDWKTKSFKYQTINSNKEQVSRTVDYKDLWHLLTVA
B8I085_RUMCH          YFGLLQSINNLVLVE--DN-------------NTLTLNNDQRAKIIEYAHFKNE------
N9W911_9CLOT          EFVLYDNINKLSIVC--DG-------------EKRKLNNKERDLIVKEAYNKKE------
B1GZM3_ENDTX          LFKVLCTINNTTFTDMKTG-------------EIRSFSKEEIGKTLETVKNVKD------
CAS9_PASMU            RFVWLTKLNNLRILE--DG-------------AERALNEEERQLLINHPYEKSK------
F9QBH3_9PAST          RFVWITKLNNLRIQE--NG-------------LERALNDNERLILIEQPYEKAK------
A9HKP2_GLUDA          RFRLLARLLNLRITTPDG--------------ERPLTVDEIALVTRDLGKTAK-------
I3TWJ0_TISMK          RFRLLTRLINLRIATAEG--------------ERRFTPEDLARVSAELGATAK-------
Q20XX4_RHOPB          LFRFLSRLANLKLAVGRSP-------------ERRLTAEEIALAAKGFGETKKT------
I7GTK8_9HELI          EFIALSRTINTLINLSKES-------------GEIYNRAIILQIVESTLKKGE-------
D3UFL8_HELM1          EFVALTKSINFLKNLTNRH-------------GLCFSQEDMCVYLGKILQEAQKNEK---
A8LN05_DINSH          RRVLYETVNQLRVTADGRE-------------ARPLTREERDQVIHALDNKKPTKSLSSM
A1WH93_VEREI          RFRILQEVNNLRLLDEALR-------------EVPLNLAQRDAVVSALEGKK--------
J6LE60_9RHOB          ARGIYERLAHLRITTGPVS-------------DRGLTRPERDVLASALLAGK--------
CAS9A_STRTD           EFNLLNDLNNLTVPTE----------------TKKLSKEQKNQIINYVKNEKAM------
A8AY02_STRGC          EFNLLNDLNNLTVPTE----------------TKKLSEEQKKLIIEYAKSAKTL------
C4ZA16_AGARV          EYNVLNDLNNLTIN------------------GRKLEENEKHEIVERIKSS---------
Q73QW6_TREDE          YQLRKMELEKILSNAEKHFSFLKQKDEKGLSHSEKIIMLLTFKIPYYIGPINDNHKKFFP
B0RZQ7_FINM2          HQIHLFELDKILENLAKNYPSFNNKKEE-FTKIEKIRKTFTFRIPYYVGPLNDYHKNNGG
G4Q6A5_ACIIR          YQLYYYELKTILNKAASYLPFLTQCGKDAISNQDKLLSIMTFRIPYFVGPLRKDN----S
R5GJ26_9FIRM          YQLYYTELKKVLENAKRYIPQLNVTDEYGSA-ADKILSLMTFRIPYYVGPLVKKND---S
CAS9_STRP1            HQIHLGELHAILRRQEDFYPFLKD-------NREKIEKILTFRIPYYVGPLARG----NS
CAS9_STRMU            HQIHLQEMRAIIRRQAEFYPFLAD-------NQDRIEKLLTFRIPYYVGPLARG----KS
CAS9B_STRTD           YQIHLQEMRAILDKQAKFYPFLAK-------NKERIEKILTFRIPYYVGPLARG----NS
CAS9_LISIN            HQLHLEELEAILHQQAKYYPFLKE-------NYDKIKSLVTFRIPYFVGPLANG----QS
E6LI02_ENTI1          HQVHAEELRAILRKQEKYYSFLKE-------NHEKIEQIFKVRIPYYVGPLAKHNE--QS
A0A142LIG4_9PROT      RHVWLTRLNNLRIIVDGRT------------RPLADAERTMALSLPYEQVGDFTYKQLRA
Q7MRD3_WOLSU          KFIAISKFFSTVIIDNEG-------------WEQKIIERKTLEELLDFAVSREK------
U2LZE9_TRELE          KIRILQEVYNMDYIDEYGK-------------VLPLEDTQTDSLISLLDKKEK-------
E1QW44_OLSUV          YQLHLEELHTILENQGKHYPFLLS-------EEDKIESLVSFRIPYYVGPLTRKNAAIGH
A0A1B3SLT6_9MOLU      LFNILNDLNNLKIEGLSSG----------------LTYEQKYEIINSVIEHKEVK-----
R7EW40_9BACT          VCRIYEAINNIRLVNSRLKRRKAAVAPSLFDDIENLPLDYRKQQPEFILNEEEKQR----
Q2RX87_RHORT          DFIIRQTLANLRLPSTSAD------------EPRPLTDEEHAKALALLSTARFV------
I0AP30_IGNAJ          EFRIWQDIHNIKVIRKESE-----------VNGKKKINIDETQLYINENIKEKLFELFNS
D1AUW6_STRM9          IFTMLQKLNDIRYVKFTSED----------KIEKKKLSKEVIHKLYDLVVEKNK------
B2KB46_ELUMP          ERRLWETLNNARYSDPIVDIVTGEI---TGYYEKQFTKEQKQKLFDYLLTGSEL------
F0RSV0_SPHGB          ERRLWEAINNARIKMPMQEGAAKR-------YQSASFSDEQRHILFHIARSGTD------
E9S7M7_RUMAL          IYAFVNVLSQYTYTNNRGE--------------SVFDTSFANDLINSALKNGSMD-----
Q4A5I2_MYCS5          IFNLQNEICTIKNEFTEFKNWWLNAE-----QKSEILKFVFTELFNWKDKKYSDKK----
Q7NAI2_MYCGA          IFNEINELSTIRSYSIYLTGWF---------INQEFKKAYLNKLLDLLIKTNSEKP----
Q6KIQ7_MESM1          VFDITNKLTDWKHKNEYISERLKRKILLSRFLNKDSKSAVEKILKEENIKFENLSEIAYN
E6WZS9_NITSE          LYRLYKKLADLNIDGYEVTQ------------------EDREKVIEWVEKKIAQ------
K1LM04_9FLAO          EYKVWEQINKLIVNTKIEAGTNRKGEKKYKYIDRPIPTALKEWIFEELQNKKEITF----
                                                                                  

Q5L8F8_BACFN          ----RLCQEEKELLAQELFIRDKMTKSEVLKLLFDNPQELDLNFKTIDGNKTGYALFQAY
F9YQX1_CAPCC          --------EAKQALFNELNLKGNLKAYYCLEILGYSPKEWEMNYSVLEGNRTNKALYEAY
F0P0P2_WEEVC          ----DILTYLIEPIVKSKYPNAKGKAFKDELKKELKKYRWNYVYDADKDESKSYPMNETR
R7D4J2_9BACE          ----ELVAFLLGGKAN---------------KKQIKAYRWNYM----DDDTKGYPCNETR
G8XA12_FLACA          ----TSDTYLYDFAIEKLKLEPKNAKAFSKTKLKKDFASLSLAAIAKILPYLKQGLLYSH
G2Z1C1_FLABF          ----TSDVYLYEFAIDKLGLDEKNAKAFSKTKLKKDFASLSLSAINKILPYLKEGLLYSH
B8I085_RUMCH          -----IKYSEIRKLLDIEPEILFKAHNLTHKNPSGNNESKKFYEMKSYHKLKSTLPTDI-
N9W911_9CLOT          -----IKYSALRKLLNLDENSRFSTLTYSIDKDVSKTENTKFVSLSGYYEIKRAIEKGIS
B1GZM3_ENDTX          -----VKYAKIRKDLGLEDSVKFSGVDYRENAK-SKGEGEIFVSMKTYHEIKSKIEKLS-
CAS9_PASMU            -----LTYAQVRKLLGLSEQAIFKHLRYSKEN----AESATFMELKAWHAIRKALENQGL
F9QBH3_9PAST          -----LTYAQVRSILNLSDEAIFKGLRYSGEDKKAIETKTTLMEMKAYHQIRKVLEGNNL
A9HKP2_GLUDA          -----LSIKRVRTLIGLEDNQRFTTIRPE-DEDRD-----IVARTGGAMTGTATLRKALG
I3TWJ0_TISMK          -----LPVSRVRALIGLLPDERFTTIRVE-DEDRD-----IVARTGEAAPGTWRLRKTLG
Q20XX4_RHOPB          -----ITFKSLREALDLDPNARFSGIGKDKEASLD-----VVARTGGAAYGTKTLKDALG
I7GTK8_9HELI          -----ISYKELREIIRLDERLRFKDPRLDYSREIKEAEKVKFLEFKQLKGFKKALGESF-
D3UFL8_HELM1          ----GLTYSKLKLLLDLPSDFEF----LGLDYSGKNPEKAVFLSLPSTFKLNKITQDR--
A8LN05_DINSH          ----VLKLPALAKVLKLRDGERFTLETGVRDAIACDPLRASPAHPDRFGPRWSILDADAQ
A1WH93_VEREI          ----ELSFAAIRKLLTLSG--KFNLEDEKRAELKGNATSVILARKDLFGDAWAGFDAAVQ
J6LE60_9RHOB          ----SLTFKAVRKTLKILPHALVNFEEAGEKGLDGALTAKLLSKPDHYGAAWHGLSFAEK
CAS9A_STRTD           ------GPAKLFKYIAKLLSCDVADIKGYRIDKSGKAEIHTFEAYRKMKTL---ETLDIE
A8AY02_STRGC          ------GASTLLKYIAKMIDASVDQIRGYRVDVNNKPEMHTFEVYRKMQSL---ETIKVE
C4ZA16_AGARV          ------NTINMRKIISDCMGENIDDFAGARIDKSGKEIFHKFEVYNKMRKALLEIGIDIS
Q73QW6_TREDE          ----DRCWVVKKEKSPSGKTTPWNFFDHIDKEKTAEAFITSRTNFCTYLVGESVLPKSSL
B0RZQ7_FINM2          ----NAWIFRNKGE----KIRPWNFEKIVDLHKSEEEFIKRMLNQCTYLPEETVLPKSSI
G4Q6A5_ACIIR          ----EHAWLERKA----GKIYPWNFNDKVDLDKSEEAFIRRMTNTCTYYPGEDVLPLDSL
R5GJ26_9FIRM          ----SNAWIVRRGE---GRILPWNFDELVDKDKCEDEFIRRMTCKCTYIAGKNVLPKNSL
CAS9_STRP1            ----RFAWMTRKSE---ETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSL
CAS9_STRMU            ----DFAWLSRKSA---DKITPWNFDEIVDKESSAEAFINRMTNYDLYLPNQKVLPKHSL
CAS9B_STRTD           ----DFAWSIRKRN---EKITPWNFEDVIDKESSAEAFINRMTSFDLYLPEEKVLPKHSL
CAS9_LISIN            ----EFAWLTRKAD---GEIRPWNIEEKVDFGKSAVDFIEKMTNKDTYLPKENVLPKHSL
E6LI02_ENTI1          ----RFAWNIRKSD---EPIRPWNMNDVVDENASAVAFIERMTIKDIYL-NENVLPRHSL
A0A142LIG4_9PROT      ----ALVKAGLMPDSFKFASLAYPSEFQKAEGKAKDPESAALTKLAAWQELRATLKKADL
Q7MRD3_WOLSU          -----VEFRHLRKFLDLSDNEIFKGLHYKGKPKTAKKREATLFDPNEPTELEFDKVEAEK
U2LZE9_TRELE          -----LSFAAMKKELRLDESCTFNLERGGREYLQGNITAVKLRNKNRFGELWDSLSLAEQ
E1QW44_OLSUV          DGKERFAWSSRKDGMEHAVITPWNWEEIIDRDKSAEDFIMRMTGDCTYLQGEPVLPKCSL
A0A1B3SLT6_9MOLU      ------NKNINLKQIAKIAKVDVSGITGYRIKKNNTPDFTNFEFINKLRAASIKANLDYS
R7EW40_9BACT          ----IFNYLNTNERLTETKLLELIGLKRVDGFKSDMSLAKGIAGNKTYCSIAKALANLPN
Q2RX87_RHORT          ------EWPALRRALGLKRGVKFTAETERNGAKQAARGTAGNLTEAILAPLIPGWSGWDL
I0AP30_IGNAJ          KDSLSEKDILELISLNIINSGIKISKKEEETTHRINLFANRKELKGNETKSRYRKVFKKL
D1AUW6_STRM9          ----TLTYDLIEKSIDEENIKLLNIPKLSKSKYVELRKSYFKERNDNENLTEEEINAFNE
B2KB46_ELUMP          ------TPAQTKKLLGLKNTNFEDIILQGRDKKAQKIKGYKLIKLESMPFWARLSEAQQD
F0RSV0_SPHGB          -----ITPKLVQKEFPALKTSIIVLQGKEKAIQKIAGFRFRRLEEKSFWKRLSEEQKDDF
E9S7M7_RUMAL          ----------KRELKAIAKSYHIDISDKNSDTSLTKCFKYIKVVKPLFEKYGYDWDKLIE
Q4A5I2_MYCS5          -FNKNLQDKIKKYLLNFALENFNLNEEILKNRDLENDTVLGLKGVKYYEKSNATADAALE
Q7NAI2_MYCGA          ---IDARQFKKLREETIAESIGKETLKDVESEEKLEKDDHKWKLKGLKLNTNGKIQYNDL
Q6KIQ7_MESM1          KDDNKINLPIINAYHSLTTIFKKHLINFENYLISNENDLSKLMSFYKQQSEKLFVPNEKG
E6WZS9_NITSE          ------GKNLKKITHKDLRKILGLAPEQKIFGVEDERIVKGKKEPRTFVPFFFLADIAKF
K1LM04_9FLAO          ----SAIFKKLKAEFDLREGIDFLNGMSPKDKLKGNETKLQLQKSLGELWDVLGLDSINR
                                                                                  

Q5L8F8_BACFN          SKMIEMSGHEPV---------------DFKKPVEKVVEYIKAVFDLL-------------
F9YQX1_CAPCC          LKITDLEGYDAKNHLKVKLNKDEVELDDLKVPASEIKDMVQAIFKEA-------------
F0P0P2_WEEVC          YELRKRLDKVENV----------PADFMTRKIEQHLWHIIYSVTDKI-------------
R7D4J2_9BACE          ASLLKYLREAQT-----------DSSFLTREREEALWHILYSISDKG-------------
G8XA12_FLACA          AVFMANIENIVDADIWK-------DEEQQKFIQSKIVELVDNYIVEK-------------
G2Z1C1_FLABF          AVFVANIENIVDENIWK-------DEKQRDYIKTQISEIIENYTLEK-------------
B8I085_RUMCH          ---WGKLHS-------------------NKESLDNLFYCLTVYKNDN-------------
N9W911_9CLOT          KEYWNEIKN-------------------NKDMLNNIAYVLTLGKTDK-------------
B1GZM3_ENDTX          KEKWDNLKG-------------------NTELLDSIVNIIANLKDDE-------------
CAS9_PASMU            KDTWQDLAK-------------------KPDLLDEIGTAFSLYKTDE-------------
F9QBH3_9PAST          KAEWTELKE-------------------NSTLLDEIGTAFSLYKTDE-------------
A9HKP2_GLUDA          EALWTDMQE-------------------RPEQLDAIVQVLSFFEANE-------------
I3TWJ0_TISMK          EALWAEMQA-------------------RPDQLDAIAHVLSFFEATA-------------
Q20XX4_RHOPB          DAPWRSLSR-------------------TPETLDRIAEILSFREDIT-------------
I7GTK8_9HELI          ------TTL-------------------AISQLDEIAEHIALIKDRV-------------
D3UFL8_HELM1          ------------------------------KTQDKIANILGANKDWE-------------
A8LN05_DINSH          WEVISRIRRVQSDAEHA----ALVDWLTEAHGLDRAHAEATAHAPLP-------------
A1WH93_VEREI          DEIVWRLVSQESEG-------ALIAWLQQHTGVDGVCAEAIVNTRLP-------------
J6LE60_9RHOB          DTFVGKLLDEADEE-------RLIRRLVTENRLSEDAARRCASIPLA-------------
CAS9A_STRTD           QMD--------------------------RETLDKLAYVLTLNTERE-------------
A8AY02_STRGC          ELP--------------------------RKVLDELAHILTLNTERE-------------
C4ZA16_AGARV          NYS--------------------------REELDEIGYIMTINTDKE-------------
Q73QW6_TREDE          LYSEYTVLNEINNLQIIIDGKNICDIKL---KQKIYEDLFKKYKKITQKQISTFIKHEGI
B0RZQ7_FINM2          LYSEYMVLNELNNLRINGKP---LDTDV---KLKLIEELFKKKTKVTLKSIRDYMVRNNF
G4Q6A5_ACIIR          IYEKFMILNEINNIRIDGYP---ISVDV---KQQVF-GLFEKKRRVTVKDIQNLLLSLGA
R5GJ26_9FIRM          LYCKFMVLNEINNIKINGER---ISVGD---KQKIYTELFEKKRKVTVRDIRNLLTSEGR
CAS9_STRP1            LYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYF--KK
CAS9_STRMU            LYEKFTVYNELTKVKYKTE-QGKTAFFDANMKQEIFDGVFKVYRKVTKDKLMDFLE--KE
CAS9B_STRTD           LYETFNVYNELTKVRFIAESMRDYQFLDSKQKKDIVRLYFKDKRKVTDKDIIEYL---HA
CAS9_LISIN            CYQKYLVYNELTKVRYIND-QGKTSYFSGQEKEQIFNDLFKQKRKVKKKDLELFL---RN
E6LI02_ENTI1          IYEKFTVFNELTKVLYADD-RGVFQRFSAEEKEDIFEKLFKSERKVTKKKLENYL---RI
A0A142LIG4_9PROT      ESEWQQISCAALEG--------------QPETLDEIAGVLSVFKDDD-------------
Q7MRD3_WOLSU          KAWISLRGAAKLRE------------ALGNEFYGRFVALGKHADEATK------------
U2LZE9_TRELE          DRIVEKLIT--------------------ADEDAEIISILKQYDLTD-------------
E1QW44_OLSUV          LYEEFCALNEFNGAHWTVDG-DDERRFDAAQRERIMCDLFRRTRSVTYNKVSDWLERKYN
A0A1B3SLT6_9MOLU      FIKLDNIKV-----------------------LDQIAKILTVYQTAE-------------
R7EW40_9BACT          GENLLRFDLKI------------------TEKLDKTSGALEPVIDLA-------------
Q2RX87_RHORT          DRKDRVFSDLWAAR----------------QDRSALLALIGDPRGPT-------------
I0AP30_IGNAJ          GFDGEYILNHPSKLNRLWHSDYSNDYADKEKTEKSILSSLGWKNRNGKWEKSKNYDVFNL
D1AUW6_STRM9          KLNNERMKQELIRN--------------NLKAYKELKSKFKKNNIDE-------------
B2KB46_ELUMP          SFLYDWNSCP---------------------DEKLLTEKLSNEYHLT-------------
F0RSV0_SPHGB          FSAWTNTPDD------------------KRLSKYLMKHLLLTENEVV-------------
E9S7M7_RUMAL          NYTDTDNNV-----------------------LNRIGIVLSQAQTPK-------------
Q4A5I2_MYCS5          FSSLKPLYVFIKFLKEKKLDLNYLLGLENTEILYFLDSIYLAISYSSDLKER--------
Q7NAI2_MYCGA          SSLAKFVHKLKQHLKLDFLLEDQYTPLDKINFLQSLYVYLGKHLRYSNRVDSANL-----
Q6KIQ7_MESM1          SYEINQNNN-------------------VLHIFDAISNILNKFSTIQ-------------
E6WZS9_NITSE          KELFASIQKH-------------------PDALQIFRELAEILQRSK-------------
K1LM04_9FLAO          QIELWNILYNEKGN----------EYDLTSDRTSKVLEFINKYGNNIVDD----------
                                                                                  

Q5L8F8_BACFN          --------------------NWNTDILGFNSNEE---LDNQPYYKLWHLLYSFEGD----
F9YQX1_CAPCC          --------------------GINTDILHFNAELDGKDFENQASYQLWHLLYSYEGD----
F0P0P2_WEEVC          --------------------EFEKALKSFANKYDLHQESFVENFKRFKPFDSDYGT----
R7D4J2_9BACE          --------------------ELKSALGKFAVKHGLN-ERFVTVFSKFPPFKKDYGS----
G8XA12_FLACA          --------------------SKLELINGLLKIYNTEDKEGRKVYYSKEAESLFEAD----
G2Z1C1_FLABF          --------------------SRFEIINGLLKEYKSENEDGKRVYYSKEAEQSFEND----
B8I085_RUMCH          --------------------EIKDYLQANNLDYLIEYIAKL-------PTFNKFKH----
N9W911_9CLOT          --------------------EIEEQLIKRNIDKKIIESVID-------ISFSKFNN----
B1GZM3_ENDTX          --------------------SIKKEFQKLKIDEDIIDVLLN-------FEFKKFIN----
CAS9_PASMU            --------------------DIQQYLTNKVPNSVINALLVS-------LNFDKFIE----
F9QBH3_9PAST          --------------------DISTYLAGKLSQPVLNALLEN-------LSFDKFIQ----
A9HKP2_GLUDA          --------------------TITEKLREIGLTLAVLDVLLTALDAGVFAKFKGAAH----
I3TWJ0_TISMK          --------------------KIRSELDRLGLPAAVIEALDRGLEDGAFAKFKGAGH----
Q20XX4_RHOPB          --------------------SIRNGLEDLGLDSLVVEALMQAAANGDFKEFTRAGH----
I7GTK8_9HELI          --------------------KLNEKLESYALTKE--QREALSN-----LSFSAHIN----
D3UFL8_HELM1          --------------------AILKELESLQLSKEQIQTIKDAK-----LNFSKHIN----
A8LN05_DINSH          --------------------DGYGRLGLTATTRILYQLTADVVTYADAVKACGWHH----
A1WH93_VEREI          --------------------DGYGRLSRKALERIVPALQREVCTYDKAVQAAGFAH----
J6LE60_9RHOB          --------------------DGYGRLGRTANTEILAALVEETDETGTVVTYAEAVR----
CAS9A_STRTD           --------------------GIQEALEHEFADGSFSQKQVDELVQFRKANSSIFGKGWHN
A8AY02_STRGC          --------------------GIEEAINSKLKD-IFNRDQVLELVQFRKNNSSLFSKGWHN
C4ZA16_AGARV          --------------------AMMEAFQKSWID--LSDDVKQCLINMRKTNGALFNK-WQS
Q73QW6_TREDE          CNKTDEVIILGIDKE---CTSSLKSYIELKNIF--GKQVDEISTKNMLEEIIRWATIYDE
B0RZQ7_FINM2          ADK-EDFDNSEKNLE---IASNMKSYIDFNNIL--EDKFDVEMVEDLIEKITIHTG----
G4Q6A5_ACIIR          LDKHGKLT--GIDTT---IHSNYNTYHHFKSLM--ERGVLTRDDVERIVERMTYSD----
R5GJ26_9FIRM          LKAGDTFG--GIDIT---VKSSLKPQHDLKRLM--AAGVITEADAEEIIERITCTT----
CAS9_STRP1            IECFDSVEISGVEDR---FNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFE-
CAS9_STRMU            FDEFRIVDLTGLDKENKVFNASYGTYHDLCKIL-DKDFLDNSKNEKILEDIVLTLTLFE-
CAS9B_STRTD           IYGYDGIELKGIEKQ---FNSSLSTYHDLLNIINDKEFLDDSSNEAIIEEIIHTLTIFE-
CAS9_LISIN            MSHVESPTIEGLEDS---FNSSYSTYHDLLKVGIKQEILDNPVNTEMLENIVKILTVFE-
E6LI02_ENTI1          ELSISSPSVKGIEEQ---FNANFGTYLDLKKFDELHPYLDDEKYQDTLEEVIKVLTVFE-
A0A142LIG4_9PROT      --------------------EVLNELQKLGLPGGAKTENALLD-----IRFDKFHA----
Q7MRD3_WOLSU          ------------------ILTYYKDEGQKRRELTKLPLEAEMVERLVKIGFSDFLK----
U2LZE9_TRELE          ----------------------EQKKNIVATVLPSGTAMLCKEVTEILVQKMEQNK----
E1QW44_OLSUV          FTGARVRG----GQGEHGFESKLGSYIFFCKDVFKTDGLDEADYTMIEQIILWSTLFED-
A0A1B3SLT6_9MOLU      ------------------------SRKEQILKIKDIEFDQNQAEVISLLSFTGTHS----
R7EW40_9BACT          --------------------YLNEPLFLLWHTLYSISNKEELFNCLGAKFGINDPETLER
Q2RX87_RHORT          --------------------RVTEDETAEAVADAIQIVLPTGRASLSAKAARAIAQAMAP
I0AP30_IGNAJ          PLEVAKAIANLPPLKKEYGSYSALAIRKMLVVMRDGKYWQHPDQIAKDQENTSLMLFDKN
D1AUW6_STRM9          --------------------NRIKELGGIYFLDLVAELLTYSKTDEKLEYFVENVERYSL
B2KB46_ELUMP          ----------------------EEEIDNAFNEIVLSSSYAPLGKSAMLIILEKIKN----
F0RSV0_SPHGB          --------------------DALKTVSLIGDYGPIGKTATQLLMKHLEDGLTYTEA----
E9S7M7_RUMAL          -------------------------RRREKLKALNIGLDDGLINELTKLKLSGTAN----
Q4A5I2_MYCS5          -------------------NEWFKKLLKELYPKIKNNNLEIIENVEDIFEITDQEKFESF
Q7NAI2_MYCGA          --------------------KEFSDSSRLFERVLQEQKDGLFKLFEQTDKDDEKILTQTH
Q6KIQ7_MESM1          --------------------DRIRILEGYFEFSNLKKDVKSSEIYSEIAKLREFSGTSS-
E6WZS9_NITSE          -----------------------TPQEALDRLRALMAGKGIDTDDRELLELFKNKRSGTR
K1LM04_9FLAO          -------------------NAEETAIRISKIKFARAYSSLSLKAVERILPLVRAGKYFNN
                                                                                  

Q5L8F8_BACFN          -NTPTGNGRLIQKMTELYGFEKEY----ATILANVSFQDDYGSLSAKAIHKILPHLKEGN
F9YQX1_CAPCC          -DSKSGNELLYKLLETKFGFKKEY----AQILANVSLSDDYGSLSTKAMRKIHPYIKE-N
F0P0P2_WEEVC          -YSEKAIKKLLPLMRVGKYWSWDIIDDKTKTRIGKIITGEYDETIKNRVREKAIDLTEEN
R7D4J2_9BACE          -YSAKALKKLLPLMRMGHHWQEASFIPSTRQRMEKFINGEYDDSIDKRTYEKLESLTEVS
G8XA12_FLACA          -LRKKLVPFYKANIIIEEHEQEIIFQDLFPILMDQLKKQEFIKIGRLDKQIEAFLEGENE
G2Z1C1_FLABF          -LKKKLVLFYKSNEIENKEQQETIFNELLPIFIQQLKDYEFIKIQRLDQKVLIFLKGKNE
B8I085_RUMCH          -LSLVAMKRIIPFME------------KGYKYSDACNMAELDFTGSSK------------
N9W911_9CLOT          -LSVKAINKILPFMK------------EGFQYNEACEKAGYDFKAIYK------------
B1GZM3_ENDTX          -LSFKALRKIIPFQF------------QGQKYITASTSAGYSLKQ---------------
CAS9_PASMU            -LSLKSLRKILPLME------------QGKRYDQACREIYGHHYGEAN------------
F9QBH3_9PAST          -LSLKALYKLLPLMQ------------QGLRYDEACHEMYGDHYGKKTY---G-------
A9HKP2_GLUDA          -ISTKAARNLLPHLE------------QGRRYDEACTMAGYDHAASRLSHHGQ-------
I3TWJ0_TISMK          -ISAKACRNLLPHLQ------------QGHRYDQACRLAGYDHAASTLSHTAQ-------
Q20XX4_RHOPB          -ISARAARNIIPGLR------------EGLVYSEACARVGYDHAARLSVPLDQ-------
I7GTK8_9HELI          -LSLQALKQILPFMRGD----------NGEQCLDYDESVEKAGLKALSKDTLKG------
D3UFL8_HELM1          -LSLEALYHLLPLMR------------EGKRYDEGVEILQERGIFSKPQPKNR-------
A8LN05_DINSH          -SDG--------------------------RTGECFDRLPYYGEVLERHVIPG-------
A1WH93_VEREI          -HSDLGFDFDYAEDEVQQVGEHTIASTGEVQAQYAFKQLPYYGKALQRHVAFG-------
J6LE60_9RHOB          -RAGERTGRNWHHSDE--------------RDGVILDRLPYYGEILQRHVVPG-------
CAS9A_STRTD           -FSVKLMMELIPELYET-----------SEEQMTILTRLGKQK-TTSSS-----------
A8AY02_STRGC          -FSIKLMMELIPELYET-----------SEEQMTILTRLGKQR-SKETS-----------
C4ZA16_AGARV          -FSLKIMNELIPEMYAQ-----------PKEQMTLLTEMGVTKGTQEEF-----------
Q73QW6_TREDE          GEGKTILKTKIKAEYGKYCSDEQIKKILNLKFSGWGRLSRKFLETVTSEMPGFSE--PVN
B0RZQ7_FINM2          --NKKLLKKYIEETYPDLSSS-QIQKIINLKYKDWGRLSRKLLDGIKGTKKETEK--TDT
G4Q6A5_ACIIR          --DTKRVRLWLNNNYGTLTAD-DVKHISRLRKHDFGRLSKMFLTGLKGVHKETGE--RAS
R5GJ26_9FIRM          --DVSRLRTWLGKF--GLSAA-DAKYVSGLKYSDFGRLSREFLTEVNDVDPATGEVINPN
CAS9_STRP1            --DREMIEERLKTYAHLFDDK-VMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLK
CAS9_STRMU            --DREMIRKRLENYSDLLTKE-QVKKLERRHYTGWGRLSAELIHGIRNKESRKTILDYLI
CAS9B_STRTD           --DREMIKQRLSKFENIFDKS-VLKKLSRRHYTGWGKLSAKLINGIRDEKSGNTILDYLI
CAS9_LISIN            --DKRMIKEQLQQFSDVLDGV-VLKKLERRHYTGWGRLSAKLLMGIRDKQSHLTILDYLM
E6LI02_ENTI1          --DRSMIQNQLEQLPLNLSTK-TIKALSRRKYTGWGRLSARLIDGIHDKNSGKTILDYLI
A0A142LIG4_9PROT      -LSLKALRKIVPYME------------RGLRYDEACERAEYHHSQLHKVGEGNRK-----
Q7MRD3_WOLSU          -LSLKAIRDILPAME------------SGARYDEAVLMLGVPHKE---------------
U2LZE9_TRELE          -IPLTVAVQMLGYTY-------------ADQSVHEENELPYYGVILTGSTMGAHP-----
E1QW44_OLSUV          --RDILKRKIEEAYGGDRLTSEQIKVICKKRFTGWGRLSKRLLTDIKVNTDTGRKSIMDV
A0A1B3SLT6_9MOLU      -LSIKTMNKAIEDMWYE-----------NKNHMQVFSEKGIKPDYNIKIEGKF-------
R7EW40_9BACT          LYALDFVKEGYANKSAKFIRRILPYLMQGYGYSDACAMCGVNHSNYITKEENS-------
Q2RX87_RHORT          GIGYDEAVTLALGLHHS-----------HRPRQERLARLPYYAAALPDVGLDGDP-----
I0AP30_IGNAJ          LIQLTNNQRKVLNKYLLTLAEVQKRSTLIKQKLNEIEHNPYKLELVSDQDLEKQVLKSFL
D1AUW6_STRM9          FKEQRDIVEIIKTFPNYTKNGNLSLSLVRELNKLLMEGHDYESSLSSLNYYIDTDV----
B2KB46_ELUMP          --DLSYTEAVEEALKEGKLTKEKQAIKDRLPYYGAVLQESTQKIIAKGFSPQFKD-----
F0RSV0_SPHGB          -LERGMETGEFQELSVWEQQSLLPYYGQILTGSTQALMGKYWHSAFKEKRDSEG------
E9S7M7_RUMAL          -VSYKYMQGSIEAFC------------EGDLYGKYQAKFNKEIPDIDENAKPQ-------
Q4A5I2_MYCS5          SKTHSLSREAFNHIIPLLLSNNEGKNYESLKHSNEELKKRTEKAELKAQ-----------
Q7NAI2_MYCGA          SLSTKAMLLAITRMTNLDNDEDNQKNNDKGWNFEAIKNFDQKFIDITKTNNNLSLK----
Q6KIQ7_MESM1          -LSFGAYYKFIPNLISE-----------GSKNYSTISYEEKALQNQKNN-----------
E6WZS9_NITSE          ELSHRYILEALPLFLEGYDEK------EVQRILGFDDREDYSRYPKSLRHLHLR------
K1LM04_9FLAO          DFSQQLQSKILKLLNENVEDPFAKAAQTYLDNNQSVLSEGGVGNSIATILVYDKHT----
                                                                                  

Q5L8F8_BACFN          RYDV----------------ACVYAGYRHSESSLTREEIANKVLKDRLMLLPKNSLHNPV
F9YQX1_CAPCC          KFST----------------ACELAGYRHSKHSLTKEENDNRVLKDSLEVLKKNSLRQPV
F0P0P2_WEEVC          HFQGLQLW-----------LAQYIVYDRHSEADIAGKWNSVADLEQYLSEFKQHSLRNPI
R7D4J2_9BACE          QYRGLPGW-----------LACYVVYDRHSEGRDIERWTSPSDIDSYLAQFKQHSLHNPI
G8XA12_FLACA          EGQIFCNH------------TDKLKKLYHPSDIEVFKKKTIKDEWGNEKVVLGSPLTTSI
G2Z1C1_FLABF          TGQIFCTEEKGTAEEKEKKIKNRLKKLYHPSDIEKFKKKIIKDEFGNEKIVLGSPLTPSI
B8I085_RUMCH          ----------------------------------------LEKCNKLTVEPIIENVTNPV
N9W911_9CLOT          ----------------------------------------GEKFKKLPVIDIHE-IVNPV
B1GZM3_ENDTX          -----------------------------------------EGIKNKLVPPAKENINVAV
CAS9_PASMU            -----------------------------------------QKTSQLLPAIPAQEIRNPV
F9QBH3_9PAST          --------------------------------------KKTEENHYFLPQIPADEIRNPV
A9HKP2_GLUDA          --------------------------------------IVAKTQFNALVTEIGESIANPI
I3TWJ0_TISMK          --------------------------------------VVSKAGFNALVTELGESIANPI
Q20XX4_RHOPB          --------------------------------------V-----------------GSPV
I7GTK8_9HELI          --------------------------------------QMLPPLNEFEP-----YLSNPV
D3UFL8_HELM1          --------------------------------------QLLPPLSELAKEESYFDIPNPV
A8LN05_DINSH          ----------------------------------------SYHPDD-DDITRFGRITNPT
A1WH93_VEREI          ----------------------------------------SGDAKD-HEEKCYGKIANPT
J6LE60_9RHOB          ----------------------------------------SGEPEEKNEAARWGRLANPT
CAS9A_STRTD           -----------------------------------------NKTKYIDEKLLTEEIYNPV
A8AY02_STRGC          -----------------------------------------KRTKYIDEKELTEEIYNPV
C4ZA16_AGARV          -----------------------------------------AGLKYIPVDVVSEDIFNPV
Q73QW6_TREDE          IITAMRE-----TQNNLMELLSSE-FTFTENIKKINSGFEDAEKQFSYDGLVKPLFLSPS
B0RZQ7_FINM2          VINFLRN-----SSDNLMQIIGSQNYSFNEYIDKLRKKYIPQEISYE---VVENLYVSPS
G4Q6A5_ACIIR          ILDFMWN-----TNDNLMQLLSEC-YTFSDEITKLQEAYYAKAQLSL-NDFLDSMYISNA
R5GJ26_9FIRM          IITMMWE-----NNINLMELLSQK-YSYRSQIESMNREYYAANPLTL-DERMSEMYIPSA
CAS9_STRP1            SDGF--------ANRNFMQLIHDDSLTFKEDIQKAQ--VSGQGD--SLHEHIANLAGSPA
CAS9_STRMU            DDGN--------SNRNFMQLINDDALSFKEEIAKAQ--VIGETD--NLNQVVSDIAGSPA
CAS9B_STRTD           DDGI--------SNRNFMQLIHDDALSFKKKIQKAQ--IIGDEDKGNIKEVVKSLPGSPA
CAS9_LISIN            NDDG--------LNRNLMQLINDSNLSFKSIIEKEQ--VTTADK--DIQSIVADLAGSPA
E6LI02_ENTI1          EDESDSYI----VNRNFMQLINDDHLSFKKIIEDSQ--PYKEQQ--SAEEIVSELSGSPA
A0A142LIG4_9PROT      -------------------------------YLPPLYKSRDKDGRMVFNDELGDIPRNPV
Q7MRD3_WOLSU          -----------------------------------------KSAILPPLNKTDIDILNPT
U2LZE9_TRELE          ------------------------------------------EQDESKPELKYGKISNPT
E1QW44_OLSUV          LREGNPNN--GQRSRTMVFMEVLRDEDLGFQKAIDGLNRDYFREHNNGLMDVNDLPGSPA
A0A1B3SLT6_9MOLU      ------------------------------------------TRLPVLRNKISEMYISPV
R7EW40_9BACT          ----------------------------------------ERELKPRLERLNKGELRQPL
Q2RX87_RHORT          ------------------------------------VGPPPAEDDGAAAEAYYGRIGNIS
I0AP30_IGNAJ          EKKNESD----YLKGLKTYQAGYLIYGKHSEKDVPIVNSPDELGEYIRKKLPNNSLRNPI
D1AUW6_STRM9          -------------------------------------DWEKFPTISEIEDSLSTKITNPN
B2KB46_ELUMP          --------------------------------------KGYKTPHTNKYELEYGRIANPV
F0RSV0_SPHGB          ----------------------------------------FFKPNTNSDEEKYGRIANPV
E9S7M7_RUMAL          ------------------------------------------KLPPFKNEDDCEFFKNPV
Q4A5I2_MYCS5          -----------------------------------------QNQKYLKDNFLKEALVPLS
Q7NAI2_MYCGA          -----------------------------------------QDKRYLDDQFINDAILSPG
Q6KIQ7_MESM1          ----------------------------------------FSHSNLFEKTWVEDLIASPT
E6WZS9_NITSE          --------------------------------------------EGNLFEKEENPINNHA
K1LM04_9FLAO          --------------------------------AKEYSHDELYKSYKEINLLKQGDLRNPL
                                                                                  

Q5L8F8_BACFN          VEKILNQMVNVINVIIDIYGKP------DEIRVELARELKKNAKEREELTKSIAQTT---
F9YQX1_CAPCC          VEKILNQMINLVNALLKKYRTENPNFKFDEIRIELARELKKNAEERANMTVNINKAK---
F0P0P2_WEEVC          VEQVITETLRVVRDIWKQYGKG-AKDYFDEIHIELGREMKNTAEERKRLSSIISENETTN
R7D4J2_9BACE          VERVVLETLRTVRDIWKQV------DHIDEIHIELGRNMKLPADKRRQMTEQAWKNEQTN
G8XA12_FLACA          KNPMAMRALHQLRKVLNTLIANDQIDEDTRIHIEMARELNDANKRKGIQDFQNENKK---
G2Z1C1_FLABF          KNPMAMRALHQLRKVLNALILEGQIDEKTIIHIEMARELNDANKRKGIQDYQNDNKK---
B8I085_RUMCH          VIRALTQARKVINAIIQKYGLP------YMVNIELAREAGMTRQDRDNLKKEHENNR---
N9W911_9CLOT          VKRALAQSRKVVNAIIDKYDSP------IRINIELARELSKNFKDRKAIEKEQKENR---
B1GZM3_ENDTX          VARAFAQTRKVINAVIRKYGQF------DQINIELATELKNSKFDRSKIEEGQKKFQ---
CAS9_PASMU            VLRTLSQARKVINAIIRQYGSP------ARVHIETGRELGKSFKERREIQKQQEDNR---
F9QBH3_9PAST          VLRTLTQARKVINGVVRLYGSP------ARIHIETGREVGKSYKDRRELEKRQEENR---
A9HKP2_GLUDA          ARKALIEGLKQIWAMRNHWGLP------GSIHVELARDVGNSIEKRREIEKHIEKNT---
I3TWJ0_TISMK          ARKALTEGLKQIRAMCARWGLP------GAIHIELAREVGNSIEKRRELESQRETTT---
Q20XX4_RHOPB          TRKALSEALKQVRAVAREYGPI------DYFHIELARSVGKSAEERKQLTDGIEARN---
I7GTK8_9HELI          VARALAEYRKVLNVLLKQYGSP------HKIHIEYAREAKLSSTERQKYEKEQKDNY---
D3UFL8_HELM1          LRRALSEFRKVVNALLEKYGGF------HYFHIELTRDVCKAKSARMQLEKINKKNK---
A8LN05_DINSH          VHIGLNQLRRLVNRIIETHGKP------HQIVVELARDLKKSEEQK----RADIKRI---
A1WH93_VEREI          VHIGLNQVRTVVNALIRRYGHP------TEVVVELARDLKQSREQKQQTQREQADNQ---
J6LE60_9RHOB          VHIGLNQLRKVVNRLIAAHGRP------DQIVVELARELKLNREQK----ERLDREN---
CAS9A_STRTD           VAKSVRQAIKIVNAAIKEYGDF------DNIVIEMARETNEDDEKKAIQKIQKANKDEKD
A8AY02_STRGC          VAKSVRQAIKIINEATKKYGIF------DNIVIEMARENNEEDAKKDYIKRQKANQDEKN
C4ZA16_AGARV          VRRSVRISFKILNAVLKKYKAL------DTIVIEMPRDRNSEEQKKRINDSQKLNEKEME
Q73QW6_TREDE          VKKMLWQTLKLVKEISHITQAP-----PKKIFIEMAKGAELEPARTKTRLKILQDLYNNC
B0RZQ7_FINM2          VKKMIWQVIRVTEEITKVMGYD-----PDKIFIEMAKSEEEKKTTISRKNKLLDLYKAIK
G4Q6A5_ACIIR          VKRPIYRTLAVVNDIRKACGTA-----PKRIFIEMAR---DGESKKKRSVTRREQIKNLY
R5GJ26_9FIRM          VRRPVKRTIEMMKEYMHIMRKP-----PKRIFIEMARELTDLDNKGKRTSSRR----NTL
CAS9_STRP1            IKKGILQTVKVVDELVKVMGRHK----PENIVIEMARENQTTQKGQKNSRERMKRIEEGI
CAS9_STRMU            IKKGILQSLKIVDELVKIMGHQ-----PENIVVEMARENQFTNQGRRNSQQRLKGLTDSI
CAS9B_STRTD           IKKGILQSIKIVDELVKVMGGRK----PESIVVEMARENQYTNQGKSNSQQRLKRLEKSL
CAS9_LISIN            IKKGILQSLKIVDELVSVMGYP-----PQTIVVEMARENQTTGKGKNNSRPRYKSLEKAI
E6LI02_ENTI1          IKKGILQSLKIVDELVAIMGYK-----PKNIVVEMARENQTTGRGKQNSKPRLKGIENGL
A0A142LIG4_9PROT      VLRSLNQARKVLNALIARYGSP------SSVHIEMARELSKPFDERMKVGKEQEAYR---
Q7MRD3_WOLSU          VIRAFAQFRKVANALVRKYGAF------DRVHFELAREINTKGEIEDIKESQRKNEK---
U2LZE9_TRELE          VHVALNQTRTVVNTLIKAYGKP------QQIVVELSRDLKASREAKDRIQKTITENQ---
E1QW44_OLSUV          IRRSINQAVRIVDEIASIARKE-----PTNIFIEVTREEDDPRKKGKRTKRRYDAIK---
A0A1B3SLT6_9MOLU      VKRALIESIKIIKEIEKMNDLE-----IKDIVIELARESNSEDRKKYIADIQKKNAK---
R7EW40_9BACT          VEKILNQTINLSNAILDRFGEI------DEVRVELARELKQNKEHRAETTIRINKQE---
Q2RX87_RHORT          VHIALNETRKIVNALLHRHGPI-----LRLVMVETTRELKAGADERKRMIAEQAERE---
I0AP30_IGNAJ          VEQVIRETIFIVRDVWKSFGII------DEIHIELGRELKNNSEERKKTSESQEKNFQEK
D1AUW6_STRM9          VKHILVILRKLYNTLLFKYGRP------EKVHLELSRDFSNDFSTRNKIQKEQLENKVRR
B2KB46_ELUMP          VHQTLNELRKLVNEIIDILGKK-----PCEIGLETARELKKSAEDRSKLSREQNDNESNR
F0RSV0_SPHGB          VHQTLNELRKLMNELITILGAK-----PQEITVELARELKVGAEKREDIIKQQTKQE---
E9S7M7_RUMAL          VFRSINETRKLINAIIDKYGYP------AAVNIETADELNKTFEDRAIDTKRNNDNQ---
Q4A5I2_MYCS5          VKTSVLQAIKIFNQIIKNFGKKY---EISQVVIEMARELTKPNLEKLLNNATNSNIKILK
Q7NAI2_MYCGA          VKRILREATKVFNAILKQFSEEY---DVTKVVIELARELSEEKELENTKNYKKLIKKNGD
Q6KIQ7_MESM1          VKRSLRQTMNLLKEIFKYSEKNN--LEIEKIVVEVTRSSNNKHERKKIEGINKYRKE---
E6WZS9_NITSE          VKSLASWALGLIADLSWRYGPF------DEIILETTRDALPEKIRKEIDKAMREREK---
K1LM04_9FLAO          VEQIINEALVLIRDIWKNYGIK-----PNEIRVELARDLKNSAKERATIHKRNKDNQ---
                                                    . .*                          

Q5L8F8_BACFN          -------------------------------------------KAHEEYKTLLQTEFGLT
F9YQX1_CAPCC          -------------------------------------------TEHEKIIKILKNEFGLP
F0P0P2_WEEVC          LRIRAILEELMYDE-NMENVRPYSPMQQEALKIYEDGVLSSSVEIPEDIEKISKK----S
R7D4J2_9BACE          LRIKALLLEFARPGYDIENVRPYSPYQQDQLRIYEEAVLGAN-ECPDDISAILKKFNGLN
G8XA12_FLACA          ---------------------------------------FREEAIKEIKKLYLEECHKDV
G2Z1C1_FLABF          ---------------------------------------FREDAIKEIKKLYFEDCKKEV
B8I085_RUMCH          -----------------------------------------KAREKISDLIRQ-NGRVA-
N9W911_9CLOT          -----------------------------------------VEIEKIRTELKDLFGKEP-
B1GZM3_ENDTX          -----------------------------------------SQKDKIFKEVQELRGGMTP
CAS9_PASMU            -----------------------------------------TKRESAVQKFKELFSDFSS
F9QBH3_9PAST          -----------------------------------------KQRENAIKEFKEYFPHFAG
A9HKP2_GLUDA          -----------------------------------------ALRARERREVHDLLDLEDV
I3TWJ0_TISMK          -----------------------------------------KRRQTERDEIRGLLALEDV
Q20XX4_RHOPB          -----------------------------------------VEKAKRRKQAEEHLGRAP-
I7GTK8_9HELI          -----------------------------------------AANQAAHKKCQELGLEPSS
D3UFL8_HELM1          -----------------------------------------SENDAASQLLEVLGLPNTY
A8LN05_DINSH          -----------------------------------------RDTTEAAKKRSEKLEELEI
A1WH93_VEREI          -----------------------------------------KRNEDIRKRIAPILETSPE
J6LE60_9RHOB          -----------------------------------------RKNREENERRTAILAEHGQ
CAS9A_STRTD           ---------------------------------------AAMLKAANQYNGKAELPHSVF
A8AY02_STRGC          ---------------------------------------AAMEKAAFQYNGKKELPDNIF
C4ZA16_AGARV          ---------------------------------------YIEKKLAVTYGIK--LSPSDF
Q73QW6_TREDE          KN---------------------------------------DADAFSSEIKDLSGKIENE
B0RZQ7_FINM2          KD---------------------------------------ERDSQYEKLLTGLNKLDDS
G4Q6A5_ACIIR          RS---------------------------------------IRKDFQQEVDFLEKILENK
R5GJ26_9FIRM          LE---------------------------------------FFKKCPQDTTELRAQLEKK
CAS9_STRP1            KE---------------------------------------LGSQILKEH--------PV
CAS9_STRMU            KE---------------------------------------FGSQILKEH--------PV
CAS9B_STRTD           KE---------------------------------------LGSKILKENI--PAKLSKI
CAS9_LISIN            KE---------------------------------------FGSQILKEH--------PT
E6LI02_ENTI1          KE---------------------------------------FSDSVLKGS--------SI
A0A142LIG4_9PROT      ------------------------------------------ERNEKDKQTFVAEFGIVG
Q7MRD3_WOLSU          --------------------------------------------ERKEAADWIAETSFQV
U2LZE9_TRELE          -------------------------------------------KRNERDNKNITEITKNP
E1QW44_OLSUV          -----------------------------------------SALEKFKKDDPSLWKELCE
A0A1B3SLT6_9MOLU      ----------------------------------------------ENSEIEEKYKKTVS
R7EW40_9BACT          ---------------------------------------------RENLMLANMISELNI
Q2RX87_RHORT          -------------------------------------------RENAEIDVELRKSDRWM
I0AP30_IGNAJ          ERARKLLKELLNSS-------------------------NFEHYDENGNKIFSSFTVNPN
D1AUW6_STRM9          -----------------------------------------EVAAFEMYGANKDIVAGKD
B2KB46_ELUMP          -----------------------------------------NRIYEIYIRPQQQVIITRR
F0RSV0_SPHGB          ----------------------------------------------KEAVLAYSKYCEPN
E9S7M7_RUMAL          ------------------------------------------KENDRIVKEIIECIKCDE
Q4A5I2_MYCS5          EK---------------------------------------LDQTEKFDDFTKKKFIDKI
Q7NAI2_MYCGA          -----------------------------------------KISEGLKALGIAEDKIEEI
Q6KIQ7_MESM1          ------------------------------------------------KYEELKKVYDLP
E6WZS9_NITSE          ----------------------------------------------ALDKIIGKYKKEFP
K1LM04_9FLAO          ---------------------------------------------TINNKIKETLVKNKK
                                                                                  

Q5L8F8_BACFN          NVSRTDILRYKLYKELESCG-----------------------------YKTLYSNTYIS
F9YQX1_CAPCC          NPTRNDIIRYRLYEELKANG-----------------------------YKDLYTNEYIE
F0P0P2_WEEVC          EPTKSEIQRYKLWLEQK--------------------------------YRSPYTGRPIP
R7D4J2_9BACE          PPTSAEVLRYKCWLEQK--------------------------------YRSPYTGRTIP
G8XA12_FLACA          NPTEDDILRYQLWLEQGKCE-----------------------------IYEEGNNISIC
G2Z1C1_FLABF          EPTEDDILRYQLWMEQNRSE-----------------------------IYEEGKNISIC
B8I085_RUMCH          --SGLDILKWRLWEDQGGR--------------------------------CAYSGKPIP
N9W911_9CLOT          --TYSEVLKYRLWQMQNCE--------------------------------CAYSQQQIG
B1GZM3_ENDTX          --SSSLLLKYRLWREQDER--------------------------------CVYSGRKIS
CAS9_PASMU            EPKSKDILKFRLYEQQHGK--------------------------------CLYSGKEIN
F9QBH3_9PAST          EPKAKDILKMRLYKQQNAK--------------------------------CLYSGKPIE
A9HKP2_GLUDA          --NGDTLLRYRLWKEQGGK--------------------------------CLYTGKAIH
I3TWJ0_TISMK          --DDDTLLRYRLWKEQGGK--------------------------------CLYTGKDIH
Q20XX4_RHOPB          --SDDELLRYELAKEQNFK--------------------------------CIYSGDAID
I7GTK8_9HELI          ----TNLLKLKLWQEQGGL--------------------------------CLYSGAKIT
D3UFL8_HELM1          ----NNRLKCKLWKQQEEY--------------------------------CLYSGEKIT
A8LN05_DINSH          EDNGRNRMLLRLWEDLNPDDA--------------------------MRRFCPYTGTRIS
A1WH93_VEREI          RVRDRDIKKWILWEELNKKDI--------------------------ADRHCPYSGERIS
J6LE60_9RHOB          RDTAENKIRLRLFEEQARANA--------------------------GIALCPYTGRAIG
CAS9A_STRTD           HGHKQLATKIRLWHQQGER--------------------------------CLYTGKTIS
A8AY02_STRGC          HGHKELTTKIRLWHQQGEK--------------------------------CLYTGKNIP
C4ZA16_AGARV          SSQKQLSLKLKLWNEQDGI--------------------------------CLYSGKTID
Q73QW6_TREDE          DNLRLRSDKLYLYYTQLGK--------------------------------CMYCGKPIE
B0RZQ7_FINM2          D---LRSRKLYLYYTQMGR--------------------------------DMYTGEKID
G4Q6A5_ACIIR          SDGQLQSDALYLYFAQLGR--------------------------------DMYTGDPIK
R5GJ26_9FIRM          SDDELRSEKLYLYFAQLGK--------------------------------CMYSGESID
CAS9_STRP1            ENTQLQNEKLYLYYLQNGR--------------------------------DMYVDQELD
CAS9_STRMU            ENSQLQNDRLFLYYLQNGR--------------------------------DMYTGEELD
CAS9B_STRTD           DNNALQNDRLYLYYLQNGK--------------------------------DMYTGDDLD
CAS9_LISIN            DNQELRNNRLYLYYLQNGK--------------------------------DMYTGQDLD
E6LI02_ENTI1          DNKQLQNDRLYLYYLQNGK--------------------------------DMYTGHELD
A0A142LIG4_9PROT      AAKGGEFEKWKLYREQQGK--------------------------------CAYSIQGID
Q7MRD3_WOLSU          PLTRKNILKKRLYIQQDGR--------------------------------CAYTGDVIE
U2LZE9_TRELE          YPNREDRLKYRLWEELGSDS---------------------------FSRKCLYCGKPIS
E1QW44_OLSUV          KAPGDMDERLSLYFMQRGK--------------------------------CMYSGRPIK
A0A1B3SLT6_9MOLU      KVDIKTKTKLILFNEQDGK--------------------------------CVYSGKSID
R7EW40_9BACT          SPTRRRIQKMRMLRETDNK--------------------------------CIYCGAVVT
Q2RX87_RHORT          ANARERRQRVRLARRQNNL--------------------------------CPYTSTPIG
I0AP30_IGNAJ          PDSPLDIEKFRIWKNQSGLTDEELNKKLKDEKIPTEIEVKKYILWLTQKCRSPYTGKIIP
D1AUW6_STRM9          RLSNDDFVRIKLWEEQNKV--------------------------------CMYSGRTIE
B2KB46_ELUMP          ENPRNYILKFELLEEQKSQ--------------------------------CPFCGGQIS
F0RSV0_SPHGB          NLDKRYIERFRLLEDQAFV--------------------------------CPYCLEHIS
E9S7M7_RUMAL          VHARHLIEKYKLWEAQEGK--------------------------------CLYSGETIT
Q4A5I2_MYCS5          ENSVVFRNKLFLWFEQDRK--------------------------------DPYTQLDIK
Q7NAI2_MYCGA          LKSPTKSYKVLLWLQQDHI--------------------------------DPYSQKEIA
Q6KIQ7_MESM1          NENTTLLKKLWLLRQQQGY--------------------------------DAYSLRKIE
E6WZS9_NITSE          SIDKRLARKIQLWERQKGL--------------------------------DLYSGKVIN
K1LM04_9FLAO          ELSLANIEKVKLWEAQRHL--------------------------------SPYTGQPIP
                                                                                : 

Q5L8F8_BACFN          REKLF---SKEFDIEHIIPQARLFDDSFSNKTLEARSVNIEKGNKTAYDFVKEKFGESGA
F9YQX1_CAPCC          KQDLF---TKNIDIEHIIPKSRVFDDSFSNKTLSFRKTNLDKGERTAFDYIESKFGA---
F0P0P2_WEEVC          LSKLF---TPAYQIEHIIPQARFFDDGFSNKVICESEVNALKDKMLGLEFIQNYYGQKVT
R7D4J2_9BACE          LSKLF---TSAYEIEHIIPKQRYFDDSFSNKVICESEVNKKKGAMLGYEFIKSYHGASIT
G8XA12_FLACA          DIIGS---NPSYDIEHTIPRSISQDNSQMNKTLCSLKFNRSIKKQKMPVELSNYNDILPR
G2Z1C1_FLABF          DIIGS---NPAYDIEHTIPRSRSQDNSQMNKTLCSQRFNREVKKQSMPIELNNHLEILPR
B8I085_RUMCH          VCDLL--NDSLTQIDHIYPYSRSMDDSYMNKVLVLTDENQNKRSYTPYEVWGST------
N9W911_9CLOT          INELF--SQGYCEIDHIIPFSRCFDDSLSNKVLVLGKENQRKGNRTPFEYFGDNI-----
B1GZM3_ENDTX          FEDLL--DTGFLDIDHIIPYSKSMDDSFNNKVLCLAEENRNKKNDIPFNYYQRID-----
CAS9_PASMU            IHRLN--EKGYVEIDHALPFSRTWDDSFNNKVLVLASENQNKGNQTPYEWLQGKIN----
F9QBH3_9PAST          LHRLL--EKGYVEVDHALPFSRTWDDSFNNKVLVLANENQNKGNLTPFEWLDGKHN----
A9HKP2_GLUDA          IRQIAA-TDNSVQVDHILPWSRFGDDSFNNKTLCLASANQQKKRSTPYEWLS-GQT----
I3TWJ0_TISMK          VRQLIA-TDNSVQVDHILPWSRFGDDSFNNKTLCLASANQRKRGQTPWEWFSLTGT----
Q20XX4_RHOPB          PAGVAA-NDTRYQVDHILPWSRFGDDSYLNKTLCTARSNQNKRGRTPFEWFEADKT----
I7GTK8_9HELI          ISYLQ--DPTALQVDHIYPYSRSFDDSYMNKCLVLTKANQEKGNRTPFEAFGTDS-----
D3UFL8_HELM1          IDHLK--DQRALQIDHAFPLSRSLDDSQSNKVLCLTSSNQEKSNKTPYEWLGSDE-----
A8LN05_DINSH          AAMIF---DGSCDVDHILPYSRTLDDSFPNRTLCLREANRQKRNQTPWQAWGDTP-----
A1WH93_VEREI          ATMLL---SEAVEIEHILPFSRTLDDSLNNRTVAMRRANRIKGDRTPWEARADFEAQ---
J6LE60_9RHOB          IAELF---TSEVEIDHILPVSLTLDDSLANRVLCRREANREKRRQTPFQAFGATP-----
CAS9A_STRTD           IHDLIN-NSNQFEVDHILPLSITFDDSLANKVLVYATANQEKGQRTPYQALDSMDDA---
A8AY02_STRGC          ISDLIH-NQYKYEIDHILPLSLSFDDSLSNKVLVLATANQEKGQRTPFQALDSMDDA---
C4ZA16_AGARV          PNDIIN-NPQLFEIDHIIPRSISFDDARSNKVLVYRSENQKKGNQTPYYYLTHSHSE---
Q73QW6_TREDE          IGHVF--DTSNYDIDHIYPQSKIKDDSISNRVLVCSSCNKN--KEDKYPLKSEIQS----
B0RZQ7_FINM2          LDKLF--DSTHYDKDHIIPQSMKKDDSIINNLVLVNKNANQTTKGNIYPVPSSIRNN---
G4Q6A5_ACIIR          LEHIK--DQSFYNIDHIYPQSMVKDDSLDNKVLVQSEINGE--KSSRYPLDAAIRN----
R5GJ26_9FIRM          IERLG--SK-LYDVDHIFPQARVKDDSIENKVLVLSDLNGA--KSDRYPINADIRN----
CAS9_STRP1            INRL-----SDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRG--KSDNVPSEEVVKK----
CAS9_STRMU            IDYL-----SQYDIDHIIPQAFIKDNSIDNRVLTSSKENRG--KSDDVPSKDVVRK----
CAS9B_STRTD           IDRL-----SNYDIDHIIPQAFLKDNSIDNKVLVSSASNRG--KSDDVPSLEVVKK----
CAS9_LISIN            IHNL-----SNYDIDHIVPQSFITDNSIDNLVLTSSAGNRE--KGDDVPPLEIVRK----
E6LI02_ENTI1          IDHL-----STYDIDHIIPQSFLTDNSIDNRVLTTSKSNRG--KSDNVPSEEVVRK----
A0A142LIG4_9PROT      LNRLL--EPGYVEIDHALPYSRSFDDSKSNKVLVLAAENRNKGNRTPYEYLDGEHNS---
Q7MRD3_WOLSU          LERLF--DEGYCEIDHILPRSRSADDSFANKVLCLARANQQKTDRTPYEWFGHDAA----
U2LZE9_TRELE          GSEIF---TKDIEIEHILPFGRTLFDGETNKTIAHTSCNAFKKDRSPFEAFGSSPNG---
E1QW44_OLSUV          IEELH---TGKYEVDHIIPRSYIKDDSFENKVLVYREENQHKTDALLIDSSIRQKMG---
A0A1B3SLT6_9MOLU      VDRLLS-EPNYCEIDHIIPFSVSFDDSRSNKVLVLREENQNKKQNTPWQYFKEINRN---
R7EW40_9BACT          PSQFI--EGHGYEVEHIIPRSRLFDDSFTNKVCSCRECNAAKGNLTGYDFMKTQSEE---
Q2RX87_RHORT          HADLL---GDAYDIDHVIPLARGGRDSLDNMVLCQSDANKTKGDKTPWEAFHDKPG----
I0AP30_IGNAJ          LSKLF--DSNVYEIEHIIPRSKMKNDSTNNLVICELGVNKAKGDRLAANFISESNGK---
D1AUW6_STRM9          KYQLT---SAEVQIDHILPYSKSFDNSYSNKVLVFSNENQDKKERTPYQWLKGTEK----
B2KB46_ELUMP          PNDII---NNQADIEHLFPIAESEDNGRNNLVISHSACNADKAKRSPWAAFASAAKD---
F0RSV0_SPHGB          VADIA---AGRADVDHIFPRDDTADNSYGNKVVAHRQCNDIKGKRTPYAAFSNTSAW---
E9S7M7_RUMAL          KEDMLRDKDKLFEVDHIVPYSLILDNTINNKALVYAEENQKKGQRTPLMYMNEAQAA---
Q4A5I2_MYCS5          INEIE----DETEIDHVIPYSKSADDSWFNKLLVKKSTNQLKKNKTVWEYYQNESDPEAK
Q7NAI2_MYCGA          FDDILT-KTEKTEIDHIIPYSISFDDSSSNKLLVLAESNQAKSNQTPYEFINSGKAE---
Q6KIQ7_MESM1          ANDVIN-KPWNYDIDHIVPRSISFDDSFSNLVIVNKLDNAKKSNDLSAKQFIEKIYGIEK
E6WZS9_NITSE          LSQLL---DGSADIEHIVPQSLGGLSTDYNTIVTLKSVNAAKGNRLPGDWLAGNPD----
K1LM04_9FLAO          LSDLFD--KEKYDVDHIIPISRYFDDSFTNKVISEKSVNQEKANRTAMEYFEVGSLK---
                                  : :*  *      .   *                              

Q5L8F8_BACFN          DNSLEHYLNNIEDLFKS--------------GKISKTKYNKLKMA---EQDIPDGFIERD
F9YQX1_CAPCC          -DKLEEYVARVEDLYKN--------------NIISKAKYQKLLKK---ESEIGDGFVERD
F0P0P2_WEEVC          TSFG-EVTILTEDAYKA--------------FVKEHYDKNRSKRNKLLLEEIPEKMIDRQ
R7D4J2_9BACE          LNRGGTASIFSVEAYEN--------------FVKEHYAHNRGKMKKLLMDDVPDSFISRQ
G8XA12_FLACA          IAHWKKEAEELTRQIET--------------ISRSIKSAATKVAKDKNIRKRHYLTLKRD
G2Z1C1_FLABF          IAHWKEEADNLTREIEI--------------ISRSIKAAATKEIKDKKIRRRHYLTLKRD
B8I085_RUMCH          ------EKWEDFEARIY--------------SMHLPQSKEKRLLNRNFITKDLDSFISRN
N9W911_9CLOT          ------ERWNRFEVWVK--------------GSHLNYKKKTNLLKKKVSKEEEREWKARN
B1GZM3_ENDTX          ------RDWNLLISIIT--------------SMKNMKIAKKSRLLKQELS-DIEGFIERN
CAS9_PASMU            -----SERWKNFVALVL--------------GSQCSAAKKQRLLTQVIDD---NKFIDRN
F9QBH3_9PAST          -----SERWRAFKALVE--------------TSAFPYAKNNAS-----------------
A9HKP2_GLUDA          -----GDAWNAFVQRIE--------------TNKELRGFKKRNYLLKNAKEAEEKFRSRN
I3TWJ0_TISMK          -----PEAWEVFASRVE--------------TSKDLRGFKKRNLLLKNADEVAQRFRSRN
Q20XX4_RHOPB          -----DVEWMEYVARVE--------------NLQEVKGRKKRNYSIKDAAAIEDKFKARN
I7GTK8_9HELI          ------AKWGVITTLAQ--------------KLPHK--KRRRILNTAFNDK-EAGFKLRN
D3UFL8_HELM1          ------KKWDMYVGRVY--------------SSNFSPSKKRKLTQKNFKERNEEDFLARN
A8LN05_DINSH          -------HWHAIAANLK--------------NLPENKRWRFAPDAMTRFEGEN-GFLDRA
A1WH93_VEREI          -----GWRYEAILQRAE--------------GMPPRKRYRFAEDGYQRWLGKDRNFLARA
J6LE60_9RHOB          -------AWNDIVARAA--------------KLPPNKRWRFDPAALERFEREG-GFLGRQ
CAS9A_STRTD           ---WSFRELKAFVRESK--------------TLSNKKKEYLLTEEDISKFDVRKKFIERN
A8AY02_STRGC          ---WSYREFKSYVKDSK--------------LLSNKKKDYLLTEEDISKIEVKQKFIERN
C4ZA16_AGARV          ---WSFEQYKATVMNLSKKKE---------YAISRKKIQNLLYSEDITKMDVLKGFINRN
Q73QW6_TREDE          ----KQRGFWNFLQRNN-------------FISLEKLNRLTRAT--PISDDETAKFIARQ
B0RZQ7_FINM2          ---PKIYNYWKYLMEKE-------------FISKEKYNRLIRNT--PLTNEELGGFINRQ
G4Q6A5_ACIIR          ----KMKPLWDAYYNHG-------------LISLKKYQRLTRST--PFTDDEKWDFINRQ
R5GJ26_9FIRM          ----KMHSFWDKLHSIG-------------LIGEKKYERLTRST--GFTDDELAGFISRQ
CAS9_STRP1            -----MKNYWRQLLNAK-------------LITQRKFDNLTKAERGGLSELDKAGFIKRQ
CAS9_STRMU            -----MKSYWSKLLSAK-------------LITQRKFDNLTKAERGGLTDDDKAGFIKRQ
CAS9B_STRTD           -----RKTFWYQLLKSK-------------LISQRKFDNLTKAERGGLSPEDKAGFIQRQ
CAS9_LISIN            -----RKVFWEKLYQGN-------------LMSKRKFDYLTKAERGGLTEADKARFIHRQ
E6LI02_ENTI1          -----MDRFWRKLLNAK-------------LISERKYTNLTKKE---LTESDKAGFLKRQ
A0A142LIG4_9PROT      ------ERWRQFVGFVE-------------SNKLYRQAKRSRLLRKDFGKEQADEFRERN
Q7MRD3_WOLSU          -------RWNAFETRTSAPS----------NRVRTGKGKIDRLLKKNFDENSEMAFKDRN
U2LZE9_TRELE          ------YNWHEICSRAN--------------SLKNPAKRALFAENAMEKFERDSSFIQRQ
E1QW44_OLSUV          -------GYWRMLHDAK----------------LVGDKKFRNLFRNHIDDKAMKGFVARQ
A0A1B3SLT6_9MOLU      ---WDEYKARVYNLYVTNKKF---------GKYGTRKYENLVFEKNINDEEIQFSFINRN
R7EW40_9BACT          -------KFNEYLDRIEQ------------LCKDNKISKGKLKRLKMSASEIPSDFIERD
Q2RX87_RHORT          ---WIAQRDDFLARLDPQTAK---------ALAWRFADDAGERVARKSAEDEDQGFLPRQ
I0AP30_IGNAJ          ----CKFGEVEYTLLKYGDYL---------QYCKDTFKYQKAKYKNLLATEPPEDFIERQ
D1AUW6_STRM9          --------WNEFKQRVR---------------LNLNISNKKKENLLFEDEVVNNEFLERE
B2KB46_ELUMP          ----SKYDYNRILSNVK---------------ENIPHKAWRFNQGAFEKFIENKPMAARF
F0RSV0_SPHGB          ------GPIMHYLDETP--------------GMWRKRRKFETNEEEYAKYLQSKGFVSRF
E9S7M7_RUMAL          -----DYRVRVNTMFKS--------------KKCSKKKYQYLMLPDLNDQELLGGWRSRN
Q4A5I2_MYCS5          WNKFVAWAKRIYLVQKSDKESKDNSEKNSIFKNKKPNLKFKNITKKLFDPYKDLGFLARN
Q7NAI2_MYCGA          ---ITWEVYEAYCHKFKNGDS-------SLLDSTQRSKKFAKMMKTDTSSKYDIGFLARN
Q6KIQ7_MESM1          LKEAKENWGNWYLRNANG------------KAFNDKGKFIKLYTIDNLDEFDNSDFINRN
E6WZS9_NITSE          --------YRERIGMLSE-------------KGLIDWKKRKNLLAQSLDEIYTENTHSKG
K1LM04_9FLAO          --------YSIFTKEQF--------------IAHVNEYFSGVKRKNLLATSIPEDPVQRQ
                                                                                  

Q5L8F8_BACFN          LRNTQYIAKKALSMLNEIS-------------------------HRVVATSGSVTDKLRE
F9YQX1_CAPCC          LRETQYIAKKAKEILLQIT-------------------------PNVLSTSGGITDRLRE
F0P0P2_WEEVC          MNDTRYISKYISKVLSNLVRGEKDDEG--------------VNSKNIIPGNGKITGILKQ
R7D4J2_9BACE          LNDSRYISKLMKSILSNLVREEGEKEA--------------I-SKNLIVCTGGITDRLKK
G8XA12_FLACA          YILGKYERFTWEEPKVGFKNSQ---------------------IPDTGIITKYAQAYLKS
G2Z1C1_FLABF          YLQGKYDRFIWEEPKVGFKNSQ---------------------IPDTGIITKYAQAYLKS
B8I085_RUMCH          LNDTRYISRFLKNYIESYLQFS-----------------NDSPKSCVVCVNGQCTAQLRS
N9W911_9CLOT          LQDTKYICKYIANYINNKLKFK-----------------ESDRKQKVITINGRATSILRG
B1GZM3_ENDTX          INDTRYATRYIKDFLENNLEFKE----------------NEFIKVKVQARSGGLTSVLSY
CAS9_PASMU            LNDTRYIARFLSNYIQENLLLVG----------------KNKKN--VFTPNGQITALLRS
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          LNDTRYAARLFAEAVKLLYAFGE------RQEKGGN--------RRVFTRPGALTAALRQ
I3TWJ0_TISMK          LNDTRYAARLLAEAAKLFYPAGD------RQEKDGR--------RRVLTRPGPLTAALRH
Q20XX4_RHOPB          LTDTQWATRLLADELSRMFPPRECERAICGRADGGNDGLTIVEERRVFTRPGAITSKLRR
I7GTK8_9HELI          LNDTSYIARLVADYTETYLEFLPLVES----ENTTLSKGQKGSKKHIAIVNGVLTSTMRY
D3UFL8_HELM1          LVDTGYIGRVTKEYIKHSLSFLPLPD---------------GKKEHIRIISGSMTSTMRS
A8LN05_DINSH          LKDTQYLARISRSYLDTLFTKGG----------------------HVWVVPGRFTEMLRR
A1WH93_VEREI          LNDTSYLSRLAANYLRLVCPQG------------------------VRVIPGQMTDKLRG
J6LE60_9RHOB          LNETKYLSRLAKIYLGKICDPD-----------------------RVYVTPGTLTGLLRA
CAS9A_STRTD           LVDTRYASRVVLNALQEHFRAHK-------------------IDTKVSVVRGQFTSQLRR
A8AY02_STRGC          LVDTRYSSRVVLNALQDFYKSHQ-------------------LDTTISVVRGQFTSQLRR
C4ZA16_AGARV          INDTSYASRLVLNTIQNFFMANE-------------------ADTKVKVIKGSYTHQMRC
Q73QW6_TREDE          LVETRQATKVAAKVLEKMFP-----------------------ETKIVYSKAETVSMFRN
B0RZQ7_FINM2          LVETRQSTKAIKELFEKFYQ-----------------------KSKIIPVKASLASDLRK
G4Q6A5_ACIIR          LVETRQSTKALAILLKRKFP-----------------------DTEIVYSKAGLSSDFRH
R5GJ26_9FIRM          LVETRQSTKAVAALLAEEFP-----------------------ESEIVYVKAGLASQFRH
CAS9_STRP1            LVETRQITKHVAQILDSRMNTKYDEND------------KLIREVKVITLKSKLVSDFRK
CAS9_STRMU            LVETRQITKHVARILDERFNTETDENN------------KKIRQVKIVTLKSNLVSNFRK
CAS9B_STRTD           LVETRQITKHVARLLDEKFNNKKDENN------------RAVRTVKIITLKSTLVSQFRK
CAS9_LISIN            LVETRQITKNVANILHQRFNYEKDDHG------------NTMKQVRIVTLKSALVSQFRK
E6LI02_ENTI1          LVETRQITKHVATILDSKFNEDSN-----------------NRDVQIITLKSALVSEFRK
A0A142LIG4_9PROT      LNDTRYVCRFFKNQVEQFLKLAEG-----------------SESKRCVVLSGQLTAFLRA
Q7MRD3_WOLSU          LNDTRYMARAIKTYCEQYWVFKNS-----------------HTKAPVQVRSGKLTSVLRY
U2LZE9_TRELE          LTDNAYLSRSALRYLRCICK-------------------------DVWSVNGGMTKLLRD
E1QW44_OLSUV          IVETSQMVKLVQTLFEARYP-----------------------NTRIVPVKAGISHDLRE
A0A1B3SLT6_9MOLU      LNDTRYATSEVKNYLTFFKKELN-------------------KSYSIKTINGGFTNYIRN
R7EW40_9BACT          LRQSQYIAKKAIEILSASFR-------------------------NVYASSGAVTSFFRH
Q2RX87_RHORT          LTDTGYIARVALRYLSLVTNEPN----------------------AVVATNGRLTGLLRL
I0AP30_IGNAJ          INDTRYIGRKLAELLTPVVKDSK----------------------NIIFTIGSITSELKI
D1AUW6_STRM9          LHATSYSSRLALNIFQRLIPVSDEDKYDEHGNEK----VKYLYNRNVIAFQGKMTSMLRN
B2KB46_ELUMP          KTDNSYISKVAHKYLACLFEKPN-----------------------IICVKGSLTAQLRM
F0RSV0_SPHGB          ESDNSYIAKAAKEYLRCLFNPNN--------------------VTAVGSLKGMETSILRK
E9S7M7_RUMAL          LNDTRYICKYLVNYLRKNLRFDRSYES------SDEDDLKIRDHYRVFPVKSRFTSMFRR
Q4A5I2_MYCS5          LNDTRYATKVFRDQLNNYSKHHSKDDE--------------NKLFKVVCMNGSITSFLRK
Q7NAI2_MYCGA          LNDTRYATIVFRDALKDYANNHLVEDK---------------PMFKVVCINGGVTSFLRK
Q6KIQ7_MESM1          LSDTSYITNALVNHLTFSNSK---------------------YKYSVVSVNGKQTSNLRN
E6WZS9_NITSE          IRATSYLEALVAQVLKRYYPFPDPELR--------------KNGIGVRMIPGKVTSKTRS
K1LM04_9FLAO          IKDTQYIAIRVKEELNKIVGNEN-----------------------VKTTTGSITDYLRN
                                                                                  

Q5L8F8_BACFN          DWQLIDVMKELNWEKYKALGLVEYFEDRDGRQ----------------------------
F9YQX1_CAPCC          DWDLINVMKELNLPKYRALGLTQMEDRKYGQQ----------------------------
F0P0P2_WEEVC          DWGLNDVWNDLILPRFERMNQLTNSTDFTAWNE-KHQKFLPS------------------
R7D4J2_9BACE          DWGIHDVWNDIIFPRFKRLDEMDSSHTYITLN--THRHPIPS------------------
G8XA12_FLACA          YFKRVESVKGGAVAEFRKLWGIQESFIDENWW----------------------------
G2Z1C1_FLABF          YFKKVESVKGGMVAEFRKIWGIQESFIDENGM----------------------------
B8I085_RUMCH          RWGLNKNRE---------------------------------------------------
N9W911_9CLOT          YWGLTKIRE---------------------------------------------------
B1GZM3_ENDTX          NWGMSKDRE---------------------------------------------------
CAS9_PASMU            RWGLIKARE---------------------------------------------------
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          AWGVESLKKQDGK-----------------------------------------------
I3TWJ0_TISMK          AWGLESLKKADGK-----------------------------------------------
Q20XX4_RHOPB          AWGLEGLKKQDGK-----------------------------------------------
I7GTK8_9HELI          YLGFASKDR---------------------------------------------------
D3UFL8_HELM1          FWGVQEKNR---------------------------------------------------
A8LN05_DINSH          HWGLNSLLSDAGRGAVKA------------------------------------------
A1WH93_VEREI          KFGLNSVLGLDGK-----------------------------------------------
J6LE60_9RHOB          RWGLNSILSDSNF-----------------------------------------------
CAS9A_STRTD           HWGIEKTRD---------------------------------------------------
A8AY02_STRGC          KWGIEKSRE---------------------------------------------------
C4ZA16_AGARV          NLKLDKNRDE--------------------------------------------------
Q73QW6_TREDE          KFDIVKCRE---------------------------------------------------
B0RZQ7_FINM2          DMNTLKSRE---------------------------------------------------
G4Q6A5_ACIIR          EFGLVKSRN---------------------------------------------------
R5GJ26_9FIRM          EFGLLKCRE---------------------------------------------------
CAS9_STRP1            DFQFYKVRE---------------------------------------------------
CAS9_STRMU            EFELYKVRE---------------------------------------------------
CAS9B_STRTD           DFELYKVRE---------------------------------------------------
CAS9_LISIN            QFQLYKVRD---------------------------------------------------
E6LI02_ENTI1          TFNLYKVRE---------------------------------------------------
A0A142LIG4_9PROT      RWGLIKVRD---------------------------------------------------
Q7MRD3_WOLSU          QWGLESKDR---------------------------------------------------
U2LZE9_TRELE          KWNIDSILKRKIDDPEIANFELKNDQIGQYKK----------------------------
E1QW44_OLSUV          AAGLVKCRE---------------------------------------------------
A0A1B3SLT6_9MOLU      KFLHLGKKDR--------------------------------------------------
R7EW40_9BACT          VWGYDDILHDLNLPKYQKAELVEDVEYTTHGQT-HTAQRIKD------------------
Q2RX87_RHORT          AWDITPGPAP--------------------------------------------------
I0AP30_IGNAJ          TWGLNGVWKDILRPRFKRLESIINKKLIFQDEDDPNKYHFDL------------------
D1AUW6_STRM9          LYSLNKYTHSFESDTLDIDNK---------------------------------------
B2KB46_ELUMP          AWGLQGLMIPFAKQLITEKESESFNKDVNSNKK---------------------------
F0RSV0_SPHGB          AWNLQGIDDLLGSRHWSKDADTSPTMR---------------------------------
E9S7M7_RUMAL          WWLNEKTWGRYDKAEL--------------------------------------------
Q4A5I2_MYCS5          SMWRKNEEQVYRFNFWKK------------------------------------------
Q7NAI2_MYCGA          NFDPKSWYAKKDR-----------------------------------------------
Q6KIQ7_MESM1          QIAFVGIKNNKETEREWKRPEGFKSINSNDFLIREEGKN---------------------
E6WZS9_NITSE          LLGIKSKSR---------------------------------------------------
K1LM04_9FLAO          HWGLTDKFKLLLKERYEALLESEKFLEAEYDNYKKDFDSRKKEYEEKEVLFEEQELTREE
                                                                                  

Q5L8F8_BACFN          --------------IGRIKDWTK-RNDHRHHAMDALTVAFTKDVFIQYFNNKNASLDPNA
F9YQX1_CAPCC          --------------VEVIIDWTK-RNDHRHHAMDALTVAFTKHNHIQYLNYLNARKNEKH
F0P0P2_WEEVC          ------------VPLELSKGFQKKRIDHRHHALDALIIACATRDHVNLLNNKHAK--SRN
R7D4J2_9BACE          ------------MPLEFQRGFSKKRIDHRHHAMDAIVIACATRNIVNYLNNESARHDAKT
G8XA12_FLACA          -----------------KHYKDKDRDKHTHHTIDAITIACMPKDKYDLLAHAWRLEDEQD
G2Z1C1_FLABF          -----------------KHYKVKDRSKHTHHTIDAITIACMTKEKYDVLAHAWTLEDQQN
B8I085_RUMCH          -------------------------ESDLHHALDAAVIACADRKIIKEITNYYNEREN--
N9W911_9CLOT          -------------------------DGDKHHALDAAVVAVATQGLVQKISKYSKAREL--
B1GZM3_ENDTX          -------------------------ESYFHHAKDAIIVACSTQGMVQYISKISQQYENDK
CAS9_PASMU            -------------------------NNNRHHALDAIVVACATPSMQQKITRFIRFKEVHP
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          -----------------------RINDDRHHALDALTVAAVDEAEIQRLTKSFHEWEQ--
I3TWJ0_TISMK          -----------------------RVSDDRHHALDALAVAAISEREVQRLTRSFQEWEQ--
Q20XX4_RHOPB          -----------------------RVEDDRHHAVDALVLAATTESLLQRLTVEVQRRER--
I7GTK8_9HELI          -------------------------DNHLHHALDAVIIGFMNDSVIKAFSDFKKTQETSK
D3UFL8_HELM1          -------------------------DHHLHHAQDAIIIACIEPSMIQKYTTYLKDKETHR
A8LN05_DINSH          ----------------------KNRTDHRHHAIDAAVIAATDPGLLNRISRAAGQGEAAG
A1WH93_VEREI          ----------------------KNRNDHRHHAVDACVIGVTDQGLMQRFANASKQARENG
J6LE60_9RHOB          ----------------------KNRSDHRHHAVDAVVIGVLTRGMIQRIAHDAARAEDQD
CAS9A_STRTD           --------------------------TYHHHAVDALIIAASSQ-LNLWKKQKNTLVSYSE
A8AY02_STRGC          --------------------------TYHHHAVDALIIAASSQ-LRLWKKHSNPLIAYKE
C4ZA16_AGARV          --------------------------SYSHHAVDAMLIGYSELGYEAYHKLQGEFIDFET
Q73QW6_TREDE          -------------------------INDFHHAHDAYLNIVVGNVYNTKFTNNPWNFIKEK
B0RZQ7_FINM2          -------------------------VNDLHHAHDAFLNIVAGDVWNREFTSNPINYVKEN
G4Q6A5_ACIIR          -------------------------INDLHHAKDAFLAIVTGNVYHERFNRRWFMVNQPY
R5GJ26_9FIRM          -------------------------INDLHHAKDAYLNIVMGNIYHVKFTKDPMNFVKEY
CAS9_STRP1            -------------------------INNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGD
CAS9_STRMU            -------------------------INDYHHAHDAYLNAVIGKALLGVYPQLEPEFVYGD
CAS9B_STRTD           -------------------------INDFHHAHDAYLNAVVASALLKKYPKLEPEFVYGD
CAS9_LISIN            -------------------------VNDYHHAHDAYLNGVVANTLLKVYPQLEPEFVYGD
E6LI02_ENTI1          -------------------------INDLHHAHDAYLNAVVALSLLRVYPQLKPEFVYGE
A0A142LIG4_9PROT      -------------------------ESDRHHALDAVVVAACTHGMVKRMSDYARRKELDQ
Q7MRD3_WOLSU          -------------------------ESHTHHAVDAIIIAFSTQGMVQKLSEYYRFKETHR
U2LZE9_TRELE          -----------------------NRYDHRHHALDASVIALIDRAIVQEISRLNQIRLKNR
E1QW44_OLSUV          -------------------------ANDFHHAHDAFLACRIGLFIQKRHPSVYDNPIGLA
A0A1B3SLT6_9MOLU      -------------------------DDYKHHAVDATICAIAPIIDIKDGKTLSMLEKDLN
R7EW40_9BACT          ------------WTK---------RKDHRHHAIDALVIALTRQGYIQRLNNLNASANKEF
Q2RX87_RHORT          -------------------------RDLLPTPRDALRDDTAARRFLDGLTPPPLAKAVEG
I0AP30_IGNAJ          ------------SINPQLDKEGLKRLDHRHHALDATIIAATTREHVRYLNSLNAADNDEE
D1AUW6_STRM9          ----------------------AFILKEFEINKDNLKMTAYNVNTGLEITSETKVEKNKS
B2KB46_ELUMP          -----------------------IRLDNRHHALDAIVIAYASRGYGNLLNKMAGKDYKIN
F0RSV0_SPHGB          ----------------------KNRDDNRHHGLDAIVALYCSRSLVQMINTMSEQGKRAV
E9S7M7_RUMAL          -----------------------KKLTYLDHAADAIIIANCRPEYVVLAGEKLKLNKMYH
Q4A5I2_MYCS5          -----------------------DRDQFFHHAVDASIIAIFSLLTKTLYNKLRVYESYDV
Q7NAI2_MYCGA          -------------------------DKNIHHAVDASIISIFSNETKTLFNQLTKFADYKL
Q6KIQ7_MESM1          --------------DVKDDVLIKDRSFNGHHAEDAYFITIISQYFRSFKRIERLNVNYRK
E6WZS9_NITSE          -------------------------ETNFHHAEDALILSTLTRGWQNRLHRMLRDNYGKS
K1LM04_9FLAO          FIKEYKENYIRYKKNKLIIKGWSKRIDHRHHAIDALIVACTEPAHIKRLNDLNKVLQDWL
                                                                                  

Q5L8F8_BACFN          NEHAIKNKYFQ-----------------------------NGRAIAPMPLREFRAEAKK-
F9YQX1_CAPCC          REHSNIMGIQQLETIKVTD------------------KNGNEKRVFKAPMPNFRQVTKA-
F0P0P2_WEEVC          ERYDLQHKLRHTTPWQDKEG-----------------KVRTKFTEFKKPWETFTQDTKK-
R7D4J2_9BACE          SRMDLQRLLCTANRKL-----------------------------IDKPWKTFTQDTCK-
G8XA12_FLACA          KKAAKVLIEQAKPWKTFKE--------------------DIEKIETEILVSHFTPDNVK-
G2Z1C1_FLABF          KKEARSIIEASKPWKTFKE--------------------DLLKIEEEILVSHYTPDNVK-
B8I085_RUMCH          -------HNYKVK--------------------------------YPLPWHSFRQDLM--
N9W911_9CLOT          -------RGIRES--------------------------------D--------------
B1GZM3_ENDTX          DKMKKIKDKTENC--------------------------------IPKPWDSFRADVE--
CAS9_PASMU            YKIENRYEMVDQESGEIISPHFPEPWAYFRQEVNIRVFDNHPDTVLKEMLPDRPQANH--
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          QGLGRP------------------------------------LRRVEPPWESFRADVE--
I3TWJ0_TISMK          QGLARP------------------------------------LRHVAPPWPGFRGDVL--
Q20XX4_RHOPB          EGRPDD------------------------------------IFHCAEPWRGFRADVRRT
I7GTK8_9HELI          AAYYAHTLSKQEY-------------------------------KKQRAFIQLPSGENFR
D3UFL8_HELM1          LKSHQKAQILREG-------------------------------DHKLSLRWPMS--NFK
A8LN05_DINSH          QSAELIAR------------------------------------DTPPPWEGFRDDLR--
A1WH93_VEREI          -LTRLVQD------------------------------------MLLPWWPSYYDHVE--
J6LE60_9RHOB          --LDRVFR------------------------------------DVPVPFEDFRDHVR--
CAS9A_STRTD           DQLLDIETGELIS----------------------------DDEYKESVFKAPYQHFVDT
A8AY02_STRGC          GQFVDSETGEIVSL--------------------------SDEEYKELVFKAPYDHFVDT
C4ZA16_AGARV          GEILRKDMWDENM---------------------------SDEVYADYLYGKKWANIRNE
Q73QW6_TREDE          RD--------------------------------------NPKIADTYNYYKVFDYDVKR
B0RZQ7_FINM2          RE--------------------------------------GD--KVKYSLSKDFTRPRKS
G4Q6A5_ACIIR          ----------------------------------------------SVKTKTLFTHSIKN
R5GJ26_9FIRM          RR--------------------------------------KEQ-VFDLKIQSMLTHDAIR
CAS9_STRP1            YKVYDVRKMIAKSEQEI-----------------------GKATAKYFFYSNIMNFFKTE
CAS9_STRMU            YPHFHGHKE-------------------------------NKATAKKFFYSNIMNFFKKD
CAS9B_STRTD           YPKYNSFRER------------------------------KSATEKVYFYSNIMNIFKKS
CAS9_LISIN            YHQFDWFKA-------------------------------NKATAKKQFYTNIMLFFAQK
E6LI02_ENTI1          YGKNSIHDQ-------------------------------NKATIKKQFYSNITRYFASK
A0A142LIG4_9PROT      VAEGFVDVETGEIINAAMFQ--------------------QLHEHFPDPWPHFRDEVQMR
Q7MRD3_WOLSU          EKERPKLAVPLANF---------------------------RDAVEEATRIENTETVKEG
U2LZE9_TRELE          IEAPQMPVLRSELIEKVKHITVSFKPDHG----------RQGKLSKETLLGKIKKIEKVD
E1QW44_OLSUV          RIMRDYARMQAREY--------------------------KKSHCLAHTQGFIVNSFLSS
A0A1B3SLT6_9MOLU      SDQ----------------------------------------VIKKDQLVSIIQDISTH
R7EW40_9BACT          GKMNLEKWAAQQPHLSVS----------------------EVKKAVDNISVSFKAGKKLS
Q2RX87_RHORT          AVQARLAALGRSR---------------------------VADAGLADALGLTLASLGGG
I0AP30_IGNAJ          KREYFLSLCNHKIRDFKLPWENFTSEVKSKLLSCVVSYKESKPILSDPFNKYLKWEYKNG
D1AUW6_STRM9          GEFKTIKDELLKKELD-------------------------KKENLIEISDYFKDKVLFD
B2KB46_ELUMP          YSERNWLSKILLP-------------------------------PNNIVWENIDADLESF
F0RSV0_SPHGB          EIEAMIPIPGYAS---------------------------EPNLSFEAQRELFRKKILE-
E9S7M7_RUMAL          QAGKRITPEYEQS----------------------------KKACIDNLYKLFRMDRRTA
Q4A5I2_MYCS5          QRREDGVYLINKETGEVKKA-------------------DKDYWKDQHNFLKIRENAIEI
Q7NAI2_MYCGA          FKNTDGSWKKIDPKTG------------------------VVSEVTDENWKQIRVRNQVS
Q6KIQ7_MESM1          ETRELDDLEKNN-----------------------------IKFKEKASFDNFLLINALD
E6WZS9_NITSE          EAELKELWKKYMP------------------------------HIEGLTLADYIDEAFRR
K1LM04_9FLAO          VEHKSEFMPNFEGSNSELLEEILSLP-------------ENERTEIFTQIEKFRAIEMPW
                                                                                  

Q5L8F8_BACFN          -------------------------HLENTLISIKAKNKVITGNINKTRKKGGVNKNMQQ
F9YQX1_CAPCC          -------------------------FLENVLISHKAKNKVVTKNKNKV--AGSNKVQEVL
F0P0P2_WEEVC          -------------------------ELEKIVVNFKQNLRVINKATNYYEKIVDGKK-VMF
R7D4J2_9BACE          -------------------------VLEDMIVSFQRTLRIINKTKNYYLRFEDGKKRRVL
G8XA12_FLACA          -------------------------KQSKSIIKNRGKKVYVLKNELPVNFKNKIEGKDYF
G2Z1C1_FLABF          -------------------------KQAKKIVRVRGKKQFVAEVERDVNGK---------
B8I085_RUMCH          ------------------------ETLAGVFISRAPRRKITGPAHDETIRSPKHFNKGLT
N9W911_9CLOT          ------------------------------------------------------------
B1GZM3_ENDTX          ------------------------ESIEGIFVSFAPRHKVTGSAHKETIYSKKHLEKE--
CAS9_PASMU            ------------------------QFVQPLFVSRAPTRKMSGQGHMETIKSAKRLAEGIS
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          ------------------------ATYPEVFVARPERRRARGEGHAATIRQVKERECT--
I3TWJ0_TISMK          ------------------------AAYAQAFVARPERRRARGKGHDASIRQVVGEGPE--
Q20XX4_RHOPB          VYG--------------------SETMPGIFVSRAERRRARGKAHDATIKQIREIEGE--
I7GTK8_9HELI          VSV--------------------LEKVESVFVSKPPRKRVRGALHEATFYSPND------
D3UFL8_HELM1          DKI--------------------QESIQNIIPSHHVSHKVTGELHQETVRTKE-------
A8LN05_DINSH          ------------------------VRLDRIIVSHRADHGRIDHAARKQGRDSTAGQLHQE
A1WH93_VEREI          ------------------------RAVRHIRVSHRPDHGFEGAMMKGTAHGIREDGIRED
J6LE60_9RHOB          ------------------------ERVSTITVAVKPEHGKGGALHEDTSYGLVPDTDPNA
CAS9A_STRTD           LKS--------------------KEFEDSILFSYQVDSKFNRKISDATIYATRQAKVGKD
A8AY02_STRGC          LRS--------------------KKFEDSILFSYQVDSKYNRKISDATIYATRKAKLDKE
C4ZA16_AGARV          V----------------------VKAEKNVKYWHYVMRKSNRGLCNQTIRGTREYDGKQY
Q73QW6_TREDE          --------------------------NNITAWEKGKTIITVKDMLKR--NTPIYTRQAAC
B0RZQ7_FINM2          --------------------------KGKVIWTPEKGRKLIVDTLNK--PSVLISNESHV
G4Q6A5_ACIIR          --------------------------GNFVAWNGEEDLGRIVKMLKQNKNTIHFTRFSFD
R5GJ26_9FIRM          --------------------------NGETAWIGDGTWLETVKKQME-KNNIRYVRYSFR
CAS9_STRP1            ITLANGEIRKRPLI-------ETNGETGEIVWDKGRDFATVRKVLSM--PQVNIVKKTEV
CAS9_STRMU            ------DVRTD--------------KNGEIIWKKDEHISNIKKVLSY--PQVNIVKKVEE
CAS9B_STRTD           ISLADGRVIERPLI-------EVNEETGESVWNKESDLATVRRVLSY--PQVNVVKKVEE
CAS9_LISIN            ------DRIID--------------ENGEILWDKK-YLDTVKKVMSY--RQMNIVKKTEI
E6LI02_ENTI1          ------DYIIN--------------DDGEILWNKQETIAQVIKTLGM--HQVNVVKKVEI
A0A142LIG4_9PROT      LKIDDPAQLRSDLLRLGNYAEEDVHAVRPLFVSRAPQRRNSGAAHKETIYGQPERLKAQG
Q7MRD3_WOLSU          ------------------------VEVKRLLISRPPRARVTGQAHEQTAKPYPRIKQVKN
U2LZE9_TRELE          IDS---------------------IQTDDIASIKDDAIRTRFETKRRELGDITKAKAALK
E1QW44_OLSUV          GFD---------------------EETGEIFKDDWDAKAEVEGIRRVLNCRQCFISRMPV
A0A1B3SLT6_9MOLU      ----------------------------QYNFSRKVEKRTNKQMFNETIYSTRVTKEGLH
R7EW40_9BACT          TPGKRYVRRNGVRKCVQTGILVPRAALTKEYVYGQIKVQDGKKDLKYIFKNPEAIADDDI
Q2RX87_RHORT          GKN---------------------RADHRHHFIDAAMIAVTTRGLINQINQASGAGRILD
I0AP30_IGNAJ          KWQKVFAIQIKNDRWKAVRRSMFKEPIGTVWIKKIKEVSLKEAIKIQAIWEEVKNDPVRK
D1AUW6_STRM9          LKIVDFEEIDTVEPEIISILYKMITALKEEVYSKNRENHLHHSLDAFLLTIMNRSMQMKL
B2KB46_ELUMP          ESS-------------------VKTALKNAFISVKHDHSDNGELVKGTMYKIFYSERGYT
F0RSV0_SPHGB          ------------------------FMDLHAFVSMKTDNDANGALLKDTVYSILGADTQGE
E9S7M7_RUMAL          EKL-------------------LSGHGRLTPIIPNLSEEVDKRLWDKNIYEQFWKDDKDK
Q4A5I2_MYCS5          KNVLN-----------------NVDFQNQVRYSRKANTKLNTQLFNETLYGVKEFENNFY
Q7NAI2_MYCGA          EIAKVIDKYIQ-----------DSNIERKARYSRKIENKTNISLFNDTVYSAKKVGYEDQ
Q6KIQ7_MESM1          ELN---------------------EKLNQMRFSRMVITKKNTQLFNETLYSGKYDKGKNT
E6WZS9_NITSE          FMS--------------------KGEESLFYRDMFDTIRSISYWVDKKPLSASSHKETVY
K1LM04_9FLAO          KGFPE----------------QVEQKLKEIIISHKPKDKLLLQYNKAGDRQIKLRGQLHE
                                                                                  

Q5L8F8_BACFN          TPRG-QLHLETIYGSGK-------------QYLTKEEKVNASFDMRKIGTVSKSAYRDAL
F9YQX1_CAPCC          TPRG-QLHKETVYGKYQ-------------YYVQKEEKIGGKFDLETIKKVANPLYQSLL
F0P0P2_WEEVC          KQEGVNWAIRKPMHKET-------------VSGKIDLPRVKVS-----------------
R7D4J2_9BACE          QTKGDNWAIRKPLHKET-------------FYGEINLRRIETLSLNKALERIPDIVERDL
G8XA12_FLACA          KLKFDSKILYKIPKKKEKQTDTFYEELPKNYLNGVEGKDYFKINTTGKTFYKIPIFNQGD
G2Z1C1_FLABF          ----------AVPKK------------------AASGKTIYKLDGEGK---KLPRLQQGD
B8I085_RUMCH          SVKIPLTTVTLEKLETM-------------------------------------------
N9W911_9CLOT          ------------------------------------------------------------
B1GZM3_ENDTX          --RYVTVKKSLDKIKLS-------------------------------------------
CAS9_PASMU            VLRIPLTQLKPNLLENM-------------------------------------------
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          --PIVFERKAVSSLKEA-------------------------------------------
I3TWJ0_TISMK          --AQVFERRGLADLKEA-------------------------------------------
Q20XX4_RHOPB          --RLVFERKPVEKLTDK-------------------------------------------
I7GTK8_9HELI          ------------------------------------------------------------
D3UFL8_HELM1          ------------------------------------------------------------
A8LN05_DINSH          TAYSIVDDIHVASRTDL-------------------------------------------
A1WH93_VEREI          GRIKQRPKAKGSADHKT-------------------------------------------
J6LE60_9RHOB          ALGNLVVRKPIRSLTAG-------------------------------------------
CAS9A_STRTD           KADETYVLGKIKDIY---------------------------------------------
A8AY02_STRGC          KKEYTYTLGKIKDIYAL-------------------------------------------
C4ZA16_AGARV          KINKLDIRTKEGIKVF--------------------------------------------
Q73QW6_TREDE          KKGELFNQTIM-------------------------------------------------
B0RZQ7_FINM2          KKGELFNATIAG------------------------------------------------
G4Q6A5_ACIIR          RKEGLFDIQPL-------------------------------------------------
R5GJ26_9FIRM          RKGALFNLMPE-------------------------------------------------
CAS9_STRP1            QTGGFSKE----------------------------------------------------
CAS9_STRMU            QTGGFSKE----------------------------------------------------
CAS9B_STRTD           QNHGLDRGKPKGLFNANL------------------------------------------
CAS9_LISIN            QKGEFSKA----------------------------------------------------
E6LI02_ENTI1          QKGGFSKE----------------------------------------------------
A0A142LIG4_9PROT      GVTEKVALTALTMKDLD-------------------------------------------
Q7MRD3_WOLSU          KKKWRLAPIDE-------------------------------------------------
U2LZE9_TRELE          TEFPKLDVFKTYYVSRT-------------------------------------------
E1QW44_OLSUV          EGDTRYGGRYWGETIYSP------------------------------------------
A0A1B3SLT6_9MOLU      KIVRIDILSTEPSDIKNL------------------------------------------
R7EW40_9BACT          RTAVLERLATNDGNVSATLKQLK-------------------------------------
Q2RX87_RHORT          LRKWPRTNFEPPYPTFR-------------------------------------------
I0AP30_IGNAJ          KKEKYIYDDYAQKVIAKIVQELGLSSSMR--------------------------KQDDE
D1AUW6_STRM9          IKYNQLISVLKNKEIEIFN-----------------------------------------
B2KB46_ELUMP          LTTYKKLSALKLTDPQK-------------------------------------------
F0RSV0_SPHGB          DLVFVVKKKIKDIGVKIG------------------------------------------
E9S7M7_RUMAL          KSCEELYRENVASLYKG-------------------------------------------
Q4A5I2_MYCS5          KLEKVNLFSRKDLRKFILEDLN--------------------------------------
Q7NAI2_MYCGA          IKRKNLKTLDIHESAEE-------------------------------------------
Q6KIQ7_MESM1          IKKVEKLNLLDNRTDKI-------------------------------------------
E6WZS9_NITSE          SSRHEVPTLRKNILEAF-------------------------------------------
K1LM04_9FLAO          GTLYGISQGKEAYRIPLTKFGGS-------------------------------------
                                                                                  

Q5L8F8_BACFN          LKRLYENDNDPKKAFAGKNSLDKQPIWLDKEQMRKVPEKVKIVTLEAIYTIRKEISPDLK
F9YQX1_CAPCC          KKRLEENGGDPKKAFTGKNSLAKNPIYLDDAQTEQLPEKVKLVWLENSFSIRKDITPENF
F0P0P2_WEEVC          --------------------------------------------KGKILTATRKSLDTSF
R7D4J2_9BACE          RKKLSELLSLGYNAKRIKGYFEEHKEEWSDVNLSKIKAYYFTKQKNKRYFAARTELDTSF
G8XA12_FLACA          TIRGSLHQETTYGAIKLPDIDIETKKPLHTDKGGFILKKDIKGNEIVFFVVRKEISKISE
G2Z1C1_FLABF          TIRGSLHQDSIYGAIK---------NPLNTDE--------------IKYVIRKDLESIKG
B8I085_RUMCH          --------------------VKNTKGGISDKAVYNVLKNRLIEHNNKPLKAFAEKIYKPL
N9W911_9CLOT          ------------------------------------------------------------
B1GZM3_ENDTX          --------------------DLENIPCNENCGIIRVLKERLEKFKNDSLKAFADPVHMPT
CAS9_PASMU            --------------------VNKEREPALYAGLKARLAEFNQDP----------AKAFAT
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          --------------------DLERIK---------DGER-NEAIVEAIRSWIATGRPADA
I3TWJ0_TISMK          --------------------DLDRVK---------DPER-NQAIIEAVRAWILAGRPADA
Q20XX4_RHOPB          --------------------DLEKIPIPKPYGQVSDPKRLRDELVESLRAWIAAGKPKDR
I7GTK8_9HELI          ------------------------------------------------------------
D3UFL8_HELM1          ------------------------------------------------------------
A8LN05_DINSH          --------------------LSLKPAQLLDEPGRSGQVRDPQLRKALRVATGGKTGKDFE
A1WH93_VEREI          --------------------ITLIPIDEPRQLARHGVDAE-------------------G
J6LE60_9RHOB          --------------------EVDRVRDRALRARLGALAAPFR---------DESGRVRDA
CAS9A_STRTD           --------TQDGYDAFMKIYKKDKSKFLMYRHDPQTFEKVIEPILENY-PNKQINEKGKE
A8AY02_STRGC          ---GTKTPSKTGFYKFLDLYKTDKSQFLMYQKDRKTWDEVIEKIIEQYRPFKEYDKNGKE
C4ZA16_AGARV          ------------AKLAFSKKDSDRERLLVYLNDRRTFDDLCKIYEDYS------------
Q73QW6_TREDE          -------------------------KKGLGQHPLKKE-GPFSNISKYGGYNKVSAAYYTL
B0RZQ7_FINM2          ---------------------KKDYKKGKIYLPLKKD-DRLQDVSKYGGYKAINGAFFFL
G4Q6A5_ACIIR          -------------------------KASTGLVPRKAG----LDVVKYGGYDKSTAAYYLL
R5GJ26_9FIRM          -------------------------RKNPSLLPRKNGKNMVLPAEKYGGYNNTAASFFSL
CAS9_STRP1            ---------------------SILPKRNSDKLIARKKD---WDPKKYGGFDSPTVAYSVL
CAS9_STRMU            ---------------------SILPKGNSDKLIPRKTKKFYWDTKKYGGFDSPIVAYSIL
CAS9B_STRTD           ---------------------SSKPKPNSNENLVGAKE--YLDPKKYGGYAGISNSFTVL
CAS9_LISIN            ---------------------TIKPKGNSSKLIPRKTN---WDPMKYGGLDSPNMAYAVV
E6LI02_ENTI1          ---------------------SIQPKGESQKLIRRKQQ---WNTKKYGGFDSPVVAYAIL
A0A142LIG4_9PROT      ----------------------RLIDPHRNEKLYAAIRKRLEEFGGKADKAFAASNPLHK
Q7MRD3_WOLSU          ---------------------------------------------EKFESFKADRVASAN
U2LZE9_TRELE          ----------------------PIVSLTEKNIDSIVDEKIKEKLKTFIKEHADLSFAEQL
E1QW44_OLSUV          -----------KGKHKHEIPLKQGLDPNLYGGYSDLLYSYFLIYEASDVSSGERVLRFIG
A0A1B3SLT6_9MOLU      --------------------KELFTKDQHKLLIYNSDKKTYEYLQKIFDTYVNDVDKENK
R7EW40_9BACT          ------------------KKPLEVNGRTIEQADCFRREFVINYRVDSIKTQKDIDSIIDP
Q2RX87_RHORT          -----------------------AEVMKQWDHIHPSIRPAHRDGGSLHAATVFGVRNRPD
I0AP30_IGNAJ          KLNKFINEAKVSAGVNKNLNTTNKTIYNLEGRFYEKIKVAEYVLYKAKRMPLNKKEYIEK
D1AUW6_STRM9          -----------------------EEKGEYIDSKEFAEELQKQKIIDIDGNERGIKFNVNG
B2KB46_ELUMP          ----------------------KKTPKDFLETALLKFKGRESEMKNEKIKSAIENNKRLF
F0RSV0_SPHGB          --------------------DYEEVASAIRGRITDKQPKWYPMEMKDKIEQLQSKNEAAL
E9S7M7_RUMAL          --------------------------DPKFASSLSMPVISLKPDHKYRGTITGEEAIRVK
Q4A5I2_MYCS5          --------------------EESEKNKKNENGSRKRILTEKYIVDEILQILENEEFKDSK
Q7NAI2_MYCGA          ----------------------NKNSKVKKQFVYRKLVNVSLLNNDKLADLFAEKEDILM
Q6KIQ7_MESM1          ---------------------KKIEEFFDEDKLKENELTKLHIFNHDKNLYETLKIIWNE
E6WZS9_NITSE          ----------------------DSLNVIKDRHKLTTEEFMKRYDKEIRQKLWLHRIGNTN
K1LM04_9FLAO          ----------------KFATEKNIQKIVSPFLSGFIANHLKEYNNKKEEAFSAEGIMDLN
                                                                                  

Q5L8F8_BACFN          ------VDKVIDVGVRKILIDRLNEYGNDAKKAFSNLDKNPIWLNKEK----GISIKRVT
F9YQX1_CAPCC          K-DEKLIDKILDEGVKRILKERLQSFGNDAKKAFSDLDKNPIWLNKEK----GIAIKRVA
F0P0P2_WEEVC          N-A-KTILSITDTGIQKILLNYLKAKGNP-ELAFSPEG-----IEEMN----QNISLYND
R7D4J2_9BACE          N-KDKIENKIADTAIQKILLQHLEAYGNDVEQAFSPEG-----IDTMN----RNIRQLNG
G8XA12_FLACA          NDVQNIVDNVVRKKIENAIANSLITFKIVKKKKVAVIKEGVTIWMREPNIEKGIEGIPIK
G2Z1C1_FLABF          SDVESIVDEVVKEKIKEAIANKVLLLSSNAQQKNKLVG---TVWMNEE------KRIAIN
B8I085_RUMCH          KN-GTNGAIIRSIRVETPSYTGVFRNEGKGISDNSLMVRVDVFKKKDK---------YYL
N9W911_9CLOT          ------------------------------------------------------------
B1GZM3_ENDTX          KCPNKKGPVIRSVKIKESNKTGIEVRKGLAERGE--MVRVDVFIKDKK---------YYL
CAS9_PASMU            PFYKQGGQQVKAIRVEQVQKSGVLVRENNGVADNASIVRTDVFIKNNK---------FFL
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          PPRSPRGDIITKIRLATT--IKAAVPVRGGTAGRGEMVRADVFSKPNRRG----KDEWYL
I3TWJ0_TISMK          PPRSPRGDVIVKLRTAPAKKIKPAVPVRGGTADRGDMVRIDVFTRPNRKG----RDEWYL
Q20XX4_RHOPB          PPLSPKGDVIRKVRIQTND--KVSVEINGGTVDRGDMARVDVFRKKNKKA----VWEYYV
I7GTK8_9HELI          --PKLLKNYGGTKGVERALALGKMRKVGAKIVSNGAMVRVDIFRHKSSG-------KFYG
D3UFL8_HELM1          ---FYYQAFGGEEGVKKALKFGKIREINQGIVDNGAMVRVDIFKSKDKG-------KFYA
A8LN05_DINSH          NALRYFASKPGPYQAIRRVRIIKP-LQAQARVPVPAQDPIKAYQGGSN-----------H
A1WH93_VEREI          KPLPYKGYASGSNYCIEITKNGKG-KWEGQVISTFDAYRIKAAADAAA-----------R
J6LE60_9RHOB          KGLAQALEAFGAENGIRRVRILKPDASVVTIADRRTGVPYRAVAPGEN-----------H
CAS9A_STRTD           VPCNPFLKYKEEHGY-IRKYSKKGNGPEIKSLKYYDSKLGNHIDITPKDSN----NKVVL
A8AY02_STRGC          VDFNPFEKYRIGNGP-IRKYSKKGNGPEIKSLKYYDILLGKHKNITPDGSR----NTVAL
C4ZA16_AGARV          DAANPFVQYEKETGDIIRKYSKKHNGPRIDKLKYKDGEVGACIDISHKYGFEKGSKKVIL
Q73QW6_TREDE          IEYEEKG---NKIRSLETIPLYLVKDIQKDQDVLKSYLTDLLGKKE------------FK
B0RZQ7_FINM2          VEHTKSK---KRIRSIELFPLHLLSKFYEDKNTVLDYAINVLQLQD------------PK
G4Q6A5_ACIIR          VRFTLEDKKTQHKLMMIPVEGLYKARIDHDKEFLTDYAQTTISEILQKDK-QKVINIMFP
R5GJ26_9FIRM          VKYHSAK---GSGVVIIPVELIHAHRYEHDSSFAEEYALRVLADIVSLKKGDVLQSVEFP
CAS9_STRP1            VVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVK-----------KD
CAS9_STRMU            VIADIEKGKSKKLKTVKALVGVTIMEKMTFERDPVAFLERKGYRNVQ-----------EE
CAS9B_STRTD           VKGTIEKGAKKKITNVLEFQGISILDRINYRKDKLNFLLEKGYKDI-------------E
CAS9_LISIN            IEYAKGKN---KLVFEKKIIRVTIMERKAFEKDEKAFLEEQGYRQP-------------K
E6LI02_ENTI1          LSFDKGK----RKARSFKIVGITIQDRESFEGNPILYLSKKDYHNP-------------K
A0A142LIG4_9PROT      PDKEGNPTGPIVRTVTLEIDKLSGVPVRGGIAKNDTMLRVDVFTKAGK------------
Q7MRD3_WOLSU          QKNFYETSTIPRVDVYHKKGKFHLVPIYLHEMVLNELPNLSLGTNPEA---------MDE
U2LZE9_TRELE          QKFTETEWIGKPSAAGKTGKKYRVAKVRCINRVQTPIRITSSAVPRYLCPEDYLAAVIWQ
E1QW44_OLSUV          IPTSIAARMANQKRLEEYVSRLALQENLEHVRMVRKIMKKQLIEVDNCRLLVTAADAVTN
A0A1B3SLT6_9MOLU      PIKNPFYHFTYELNEKIVKQSNEENPPIVRYLKYDKGIINQFTKITHKYKNVKQNKEVVV
R7EW40_9BACT          AIRQKFRERFEQVGAKDFVKSIAENPICSDAEGKCAIRNVRCFTGLKPDSLACVRKDASG
Q2RX87_RHORT          ARVLVQRKPVEKLFLDANAKPLPADKIAEIIDGFASPRMAKRFKALLARYQAAHPEVPPA
I0AP30_IGNAJ          LSLQKMFNDLPNFILEKSILDNYPEILKELESDNKYIIEPHKKNNPVNRLLLEHILEYHN
D1AUW6_STRM9          KTHRLNLVKPYENFLDDIKNKIFDKRENNKLPYHVVKSKVSGALHAETILGESKGEITKR
B2KB46_ELUMP          DVIQDNLEKAKKLLEEENEKSKAEGKKEKNINDASIYQKAISLSGDKYVQLSKKEPGKFF
F0RSV0_SPHGB          QKYKESLVQAAAVLEESNRKLIESGKKPIQLSEKTISKKALELVGGYYYLISNNKRTKTF
E9S7M7_RUMAL          EIDGKLIKLKRKSISEITAESINSIYTDDKILIDSLKTIFEQADYKDVGDYLKKTNQHFF
Q4A5I2_MYCS5          SDINALNKYMDSLPSKFSEFFSQDFINKCKKENSLILTFDAIKHNDPKKVIKIKNLKFFR
Q7NAI2_MYCGA          YRANPWVINLAEQIFNEYTENKKIKSQNVFEKYMLDLTKEFPEKFSEAFVKSMIRNKTAI
Q6KIQ7_MESM1          VKIEIKNKNLNEKNYFKYFVNKKLQEGKISFNEWVPILDNDFKIIRKIRYIKFSSEEKET
E6WZS9_NITSE          DESYRAVEERATQIAQILTRYQLMDAQNDKEIDEKFQQALKELITSPIEVTGKLLRKMRF
K1LM04_9FLAO          NKLAQYRNEKGELKPHTPISTVKIYYKDPSKNKKKKDEEDLSLQKLDREKAFNEKLYVKT
                                                                                  

Q5L8F8_BACFN          ISGISNAQSLHVKKDKDGKPILDENGRNIPVDFVNTGNNHHVAVYYRPVIDKRGQLVVDE
F9YQX1_CAPCC          ISGVANAEPLHTKKDHLGKEILDKEGKSIPVDFISTGNNHHVAVYR------------DE
F0P0P2_WEEVC          GKPHQPILKVRVFEQGSKFPLGETGNKTTKYVEAAKGTNLFFGVYE--------------
R7D4J2_9BACE          GRSHQPIYKVRVYEEATKFAVGRRGNKSTKFVEAAKGTNLFFAIYEISQ--------VDG
G8XA12_FLACA          KVRIITNSVKNPIEIKVHSPLSKSRHKHKQKVYGQNDENYAMALYELDG-----------
G2Z1C1_FLABF          KVRIYANSVKNPLHIKEHSLLSKSKHVHKQKVYGQNDENYAMAIYELDG-----------
B8I085_RUMCH          VPIYVAHMIKKE----LPSKAIVPLKPESQWELIDSTHEFLFSLYQNDY-----------
N9W911_9CLOT          ------------------------------------------------------------
B1GZM3_ENDTX          VPIYVSDFKNKD----LPNKAIAALKLENEWIMIDKTYSFKFSLFKDDL-----------
CAS9_PASMU            VPIYTWQVAKGI----LPNKAIVAHKNEDEWEEMDEGAKFKFSLFPNDL-----------
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          VPVYPHQIMNRKAWPKPPMRSIVANKDEDEWTEVGPEHQFRFSLYPRSN-----------
I3TWJ0_TISMK          VPIYPHQVMNRKAWPHPPMRSVVAYKDEAGWTEIGAEHSFRFSLYPRSY-----------
Q20XX4_RHOPB          VPIYPHQIVALN---DPPDRAVIAYAEDKDWKEIDSSYEFLWSLFGLSY-----------
I7GTK8_9HELI          VPVYTMDFALGILPNKAVVVGKDQNGVIKDWLEMDSSYEFIFSLYKDDV-----------
D3UFL8_HELM1          VPIYTYDFAIGKLPNKAIVQGK-KNGIIKDWLEMDENYEFCFSLFKNDC-----------
A8LN05_DINSH          LFEIWRLPDG---EIEAQVITSFEAHTLEGEKRPHPAAKRLLRVHKGDM-----------
A1WH93_VEREI          AGQVIST-------VEADSIVRKSGWERLRGAQSQNGQPLVMRLVIGDS-----------
J6LE60_9RHOB          HVDIVQMRDGSWRGFAASVFEVNRPGWRPEWEVKKLGGKLVMRLHKGDM-----------
CAS9A_STRTD           QSVSPWRADVYFNKTTGKYEILGLKYADLQFEKGTGTYKISQEKYNDIKKK------EGV
A8AY02_STRGC          LSLNPWRTDVYYNSETKKYEFLGLKYADLCFEEG-GAYGISEVKYKKIREK------EGI
C4ZA16_AGARV          ESLVPYRMDVYYKEENHSYYLVGVKQSDIKFEKG--RNVIDEEAYARILVN------EKM
Q73QW6_TREDE          ILVPKIKINSLLKINGFPCHITG-KTND--SFLLRPAVQFCCSNNEVLYFKKIIRFSEIR
B0RZQ7_FINM2          IIIDKINYRTEIIIDNFSYLIST-KSNDG-SITVKPNEQMYWRVDEISNLKKIENKYKKD
G4Q6A5_ACIIR          MGTRHIKLNSMISIDGFYLSIGG-KSSKGKSVLCHAMVPLIVPHKIECYIKAMESFARKF
R5GJ26_9FIRM          LGSRILKVNTLLDIDGFRANITG-KDSGGKYLGISSASSLIISQVDTTYIKRVISINERI
CAS9_STRP1            LIIKLPKYSLFELENGRKRMLAS-------AGELQKGNELALPSKYVNFLYLASHYEKLK
CAS9_STRMU            NIIKLPKYSLFKLENGRKRLLAS-------ARELQKGNEIVLPNHLGTLLYHAKNIHKV-
CAS9B_STRTD           LIIELPKYSLFELSDGSRRMLASILSTNNKRGEIHKGNQIFLSQKFVKLLYHAKRISNT-
CAS9_LISIN            VLAKLPKYTLYECEEGRRRMLAS-------ANEAQKGNQQVLPNHLVTLLHHAANCEVS-
E6LI02_ENTI1          VEAILPKYSLFEFENGRRRMVAS-------ASETQKGNQLIIPGHLMELLYHSKKIINGK
A0A142LIG4_9PROT      --FHLVPVYVHHKVTGLPNRAIVASKDEDEWTAIDDSFEFLFSLYPNDL-----------
Q7MRD3_WOLSU          NFFKFSIFKDDLISIQTQGTPKKPAKIIMGYFKNMHGANMVLSSINNSP-----------
U2LZE9_TRELE          VPSKTKNAEPEYKATFFRRDEFNDDNKPKNLEKPHDAAKYICMLYKDDY-----------
E1QW44_OLSUV          ATELAFSLDEMKIISTCAKCINGADPSAIDKIGNAQDSFFDNLKRRGSD-----------
A0A1B3SLT6_9MOLU      VGSNALGYDLFYSKTLNMYKILPVTHKVAYYDTSNSDNKIKYRENDYEIEK---------
R7EW40_9BACT          KEIGFSQTRNNHHLAFYRLPDGKIIESVVSFWNGILRKRYGVPVFVHDPAAVWDRIAEMN
Q2RX87_RHORT          LAALAVARDPAFGPRGMTANTVIAGRSDGDGEDAGLITPFRANPKAAVRTMGNAVYEVWE
I0AP30_IGNAJ          NPKEAFSTEGLEKLNKKAINKIGKPIKYITRLDGDINEEEIFRGAVFETDKGSNVYFVMY
D1AUW6_STRM9          ISVFDINYKNLGKIFDKDGSQKEIYETLVKWLEAKSKDYPKLKNGNIIKKVKIVDGNKDK
B2KB46_ELUMP          AISKPTPTTTGYGYDTGDSLCVDLYYDNKGKLCGEIIRKIDAQQKNPLKYK---------
F0RSV0_SPHGB          VVKEPSNEVKGFAFDTGSNLCLDFYHDAQGKLCGEIIRKIQAMNPSYKPAY---------
E9S7M7_RUMAL          TTSSGKRVNKVTVIEKVPSRWLRKEIDDNNFSLLNDSSYYCIELYKDSKGDNNLQGIAMS
Q4A5I2_MYCS5          EDATLKNKQAVHKDSKNQIKSFYESYKCVGFIWLKNKNDLEESIFVPINSRVIHFGDKDK
Q7NAI2_MYCGA          IYNVEKDVVHRIKRLKILSSELKENKWSNVIIRSKNESGTKLSYQDTINSIALMIMRSID
Q6KIQ7_MESM1          DEIIFSQSNFLKIDQRQNFSFHNTLYWVQIWVYKNQKDQYCFISIDARNSK---------
E6WZS9_NITSE          VYDKLNAMQIDRGLVETDKNMLGIHISKGPNEKLIFRRMDVNNAHELQKERSGILCYLNE
K1LM04_9FLAO          GDNYLFAVLEGEIKTKKTSQIKRLYDIISFFDATNFLKEEFRNAPDKKTFDKDLLFRQYF
                                                                                  

Q5L8F8_BACFN          AGNPKYELEEVVVSFFEAVTRANLGLPIIDKDYKTTEGWQFLFSMKQNE-----YFVFPN
F9YQX1_CAPCC          KGN----LQEKVVSVFEAVVRANQGLPIIDKTYNQHLGWEFLFTMKQNE-----MFVFSN
F0P0P2_WEEVC          --DNQGKRSYDTIPLNIVIERQKQGLNSVPETN--EKGHRLLFSLSPND-----LVYVPI
R7D4J2_9BACE          NGNRQTSRTFSSIPLNVAVERLKQGLPPVPED---EEGNAPKYVLSPND-----LVYLPT
G8XA12_FLACA          ------KREFELINNFNLAKLLKQSQSYYPLHKEKEIKGKKILVPIEKRNNKDVILKRGQ
G2Z1C1_FLABF          ------KRDFELINIFNLAKLIKQGQGFYPLHKKKEIKGKIVFVPIEKRNKRDVVLKRGQ
B8I085_RUMCH          ----------------LVIKT--KKGITEGYYRSCHRGTGSLSLMPHFANN---------
N9W911_9CLOT          ------------------------------------------------------------
B1GZM3_ENDTX          ----------------IKIKK--KKEEIFGYFGGVHRSTGTIKIKSRHKP----------
CAS9_PASMU            ----------------VELKT--KKEYFFGYYIGLDRATGNISLKEHDGEIS--------
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          ----------------IEIIRP-SGEVIEGYFVGLHRNTGALTISAHND-----------
I3TWJ0_TISMK          ----------------VQLVKS-NGDVIEGYLVSMDRSTGAFRVFVHNN-----------
Q20XX4_RHOPB          ----------------VEISKA-NGECIDGYFRGLHRGTGAASVCKHISLG---------
I7GTK8_9HELI          ----------------ILVQKKEMQRPELCYFVSFDTSGASIKVAKHDNNFS--------
D3UFL8_HELM1          ----------------IKIQTKEMQEAVLAIYKSTNSAKATIELEHLSKYAL--------
A8LN05_DINSH          ----------------VALE--RDGRRVVGHVQKMDIANGLFIVPHNEANA---------
A1WH93_VEREI          ----------------VRME--VDGRDEVMRVVKMS-GKEMVFAPVREANV---------
J6LE60_9RHOB          ----------------VELSD-KDGQRRVKVVQQIEISANRVRLSPHNDGG---------
CAS9A_STRTD           DSDSE-----------FKFTLYKNDLLLVKDTETKEQQLFRFLSRTMPK-----QKHYVE
A8AY02_STRGC          GKNSE-----------FKFTLYKNDLILIKDTETNCQQFFRFWSRTGKDNPKSFEKHKIE
C4ZA16_AGARV          IQPGQSRADLENLGFKFKLSFYKNDIIEYEKDGK--IYTERLVSRTMPK-----QRNYIE
Q73QW6_TREDE          SQREK--------------IGKTISPYEDLSFRSYIKENLWKKTKNDEIGEKEFYDLLQK
B0RZQ7_FINM2          AILTEE-------------DRKIMESYIDKIYQQFKAGKYKNRRTTDTIIEKYEIIDLDT
G4Q6A5_ACIIR          KENNK----LRIVEKFDKITVEDNLNLYELFLQKLQHNPYNKFFSTQFDVLTNGRSTFTK
R5GJ26_9FIRM          SACEKNKQSYTIRPEFDVITSERNIEIYNMLCEKISSRPFCIKFANTSDTFVSGREKFIA
CAS9_STRP1            GSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKH-RDKPIREQ
CAS9_STRMU            ----DEPKHLDYVDKHKDEFKELLDVVSNFSKKYTLAEGNLEKIKELYAQN-NGEDLKEL
CAS9B_STRTD           ----INENHRKYVENHKKEFEELFYYILEFNENYVGAKKNGKLLNSAFQSW-QNHSIDEL
CAS9_LISIN            -----DGKSLDYIESNREMFAELLAHVSEFAKRYTLAEANLNKINQLFEQN-KEGDIKAI
E6LI02_ENTI1          -----NSDSVSYIQNNKEKFREIFEYIVDFSSKYISADANLNKIEKIFENNFHKASEQEI
A0A142LIG4_9PROT      -----------------VTITQKGKAPVRGYYASCHRGTGAFSLWAHDRASSVG------
Q7MRD3_WOLSU          --------CEGFTCTPVSMDKKHKDKCKLCPEENRIAGRCLQGFLDYWSQE---------
U2LZE9_TRELE          ------------------LEFTENGATHLCRIAGFSATNNNIDIRPIYAVS---------
E1QW44_OLSUV          -------------RCALLFSQLKLDKLSQNFYMISSDDKSKILISILDRIRAK-------
A0A1B3SLT6_9MOLU      --------------AKFKIDSTYIKKYTIFKYNELNFDYKGENMTLLVTGFN--------
R7EW40_9BACT          ENNDIRAIAESLPPRNSEFLMSLQRNEMLVLGMSDDEWNDAISAHDIAAINKHLYRVWKL
Q2RX87_RHORT          IQVKGRPRWTHRVLTRFDRTQPAPPPPPENARLVMRLRRGDLVYWPLESGDRLFLVKKMA
I0AP30_IGNAJ          ENNQTKDREFLKPNPSISVLKAIEHKNKIDFFAPNRLGFSRIILSPGDLVYVPTNDQYVL
D1AUW6_STRM9          LIKLGNKRYVEMGRTTVKILVLKKEAEEGLKFASIGRYKYNLLKSEKDVNISIWKDAIHF
B2KB46_ELUMP          -------------EQGFTLFERIYGGDILEVDFDIHSDKNSFRNNTGSAPEN--------
F0RSV0_SPHGB          -----------MKQGYSLYVRLYQGDVCELRASDLTEAESNLAKTTHVRLPNAKPGR---
E9S7M7_RUMAL          DIVHDRKTKKLYLKPDFNYPDDYYTHVMYIFPGDYLRIKSTSKKSGEQLKFEGYFISVKN
Q4A5I2_MYCS5          DIFDFDSYNKEKLLNEINLKRPENKKFNSINEIEFVKFVKPGALLLNFENQQ--------
Q7NAI2_MYCGA          PTAKKQYIRVPLNTLNLHLGDQDFDLHNIDAYLKKPKFVKYLKANEIGDEYKPWRVLTSG
Q6KIQ7_MESM1          -----------FEKDEIKINYEKLKTQKEKLQIINEEPILKINKGDLFENEEK-------
E6WZS9_NITSE          MLFIFNKKGLIHYGCLRSYLEKGQGSKYIALFNPRFPANPKAQPSKFTSDSK--------
K1LM04_9FLAO          EERNKAKLLFTLKQGDFVYLPNENEEVILDKESPLYNQYWGDLKERGKNIYVVQKFSKK-
                                                                                  

Q5L8F8_BACFN          EKTGFNPKEIDLLDVENYGLISPNLFRVQKFS-------------------LKNYVFRHH
F9YQX1_CAPCC          ESTGFNPNDIDLLDPKNKKIISPNLFRVQKFSKLQ-----------YGNSFVREFVFRHH
F0P0P2_WEEVC          EGEVFD---ETNPDVNR-------IYKVVSFSG------------------SQMFCVRQD
R7D4J2_9BACE          EKELKRREIAMPIDKSR-------IYKMVSCTG------------------KDCFFIPAN
G8XA12_FLACA          QVVFYDKTVENPKDISEIIDFRERIYIIEGLTIQRQKDKKTSKVNEYGIIQLRHFKEARK
G2Z1C1_FLABF          QVVFYDKEVENPKDISEIVDFKGRIYIIEGLSIQRIVRP-SGKVDEYGVIMLRYFKEARK
B8I085_RUMCH          ------------------------------------------------------------
N9W911_9CLOT          ------------------------------------------------------------
B1GZM3_ENDTX          ------------------------------------------------------------
CAS9_PASMU            --------------------------------------------K---------------
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          ------------------------------------------------------------
I3TWJ0_TISMK          ------------------------------------------------------------
Q20XX4_RHOPB          ------------------------------------------------------------
I7GTK8_9HELI          --------------------------------------------TLTENQKLLFSNATKE
D3UFL8_HELM1          --------------------------------------------KNEDEEKMFTDTDKEK
A8LN05_DINSH          ------------------------------------------------------------
A1WH93_VEREI          ------------------------------------------------------------
J6LE60_9RHOB          ------------------------------------------------------------
CAS9A_STRTD           LKPYDKQKFEGGEAL-------------------------------------IKVLGNVA
A8AY02_STRGC          LKPYEKAKFEKGEE--------------------------------------LKVLGKVP
C4ZA16_AGARV          TKPIDKAKFE--------------------------------------------------
Q73QW6_TREDE          KNLEIYDMLLTKHK-------------------------------------DTIYKKRPN
B0RZQ7_FINM2          LDNKQLYQLLVAFI-------------------------------------SLSYKTSNN
G4Q6A5_ACIIR          LSPEEQVQTLLNIL-------------------------------------SIFKTCRSS
R5GJ26_9FIRM          LSLNEQVKTLTNML-------------------------------------SVFKTGRAS
CAS9_STRP1            AENIIH---------------------------------------------LFTLTNLGA
CAS9_STRMU            ASSFIN---------------------------------------------LLTFTAIGA
CAS9B_STRTD           CSSFIGPTGSERKG-------------------------------------LFELTSRGS
CAS9_LISIN            AQSFVD---------------------------------------------LMAFNAMGA
E6LI02_ENTI1          AKSFIN---------------------------------------------LLTFTAMGA
A0A142LIG4_9PROT      ------------------------------------------------------------
Q7MRD3_WOLSU          --------------------------------------------------------GLRP
U2LZE9_TRELE          -----------------------------------------------------------D
E1QW44_OLSUV          ----------------------------------------------------------SN
A0A1B3SLT6_9MOLU      ----------------------------------------------------------SN
R7EW40_9BACT          GS--------------------------------------------------KDYNFKFH
Q2RX87_RHORT          VDGRLA---------------------------------------------LWPARLATG
I0AP30_IGNAJ          IKDNSSNETIINWDDNE--------------------FISNRIYQVKKFTGNSCYFLKND
D1AUW6_STRM9          CKVRYNKLKENG-------------------------------------YRLIHELIPGE
B2KB46_ELUMP          ----------------------------------------------------RVFIKVGT
F0RSV0_SPHGB          -------------------------------------------------TFVIIITFTEM
E9S7M7_RUMAL          VNEN------------------------------------------------SFRFISDN
Q4A5I2_MYCS5          ----------------------------------------------------IYYISTLE
Q7NAI2_MYCGA          TLLIHKKDKK-----------------------------------------LMYISSFQN
Q6KIQ7_MESM1          ----------------------------------------------------ELFYIVGR
E6WZS9_NITSE          ----------------------------------------------------IKQVGIGS
K1LM04_9FLAO          ----------------------------------------------------QIYFIKHT
                                                                                  

Q5L8F8_BACFN          LETTIKDTSSILRGITWI--------------------------------------DFRS
F9YQX1_CAPCC          LETTVEDRKE-LQGITYK--------------------------------------QMKN
F0P0P2_WEEVC          VATSIVYKLEFSSLNKME--------------------------------------RTID
R7D4J2_9BACE          TAVPIVDRYEYSSMNKIG--------------------------------------RALT
G8XA12_FLACA          SEEISKDNFKPDGEFKIN--------------------------------------ENKP
G2Z1C1_FLABF          ADDIKQDNFKPDGVFKLG--------------------------------------ENKP
B8I085_RUMCH          --KNVKIDIGVRTAISIE--------------------------------------KYNV
N9W911_9CLOT          ------------------------------------------------------------
B1GZM3_ENDTX          --KEIDEGIGSRCLLDFR--------------------------------------KFQV
CAS9_PASMU            -GKDGVYRVGVKLALSFE--------------------------------------KYQV
F9QBH3_9PAST          ------------------------------------------------------------
A9HKP2_GLUDA          -PKSIHSGIGTKTLLAIS--------------------------------------KYQV
I3TWJ0_TISMK          -PAEMAKGIGAKTLLNLR--------------------------------------KFNV
Q20XX4_RHOPB          -KDATVSGIGLKTLASFK--------------------------------------KFTI
I7GTK8_9HELI          E--VVGKSIGIQNLKVFE--------------------------------------KWQV
D3UFL8_HELM1          NKTMTRESCGIQGLKVFQ--------------------------------------KVKL
A8LN05_DINSH          --DTRN--NDKSDPFKWI--------------------------------------QIGA
A1WH93_VEREI          --DKRNNMPDEQDPFTYT--------------------------------------YKRA
J6LE60_9RHOB          --KLQDRHADADDPFRWD--------------------------------------LATI
CAS9A_STRTD           NSG-QCKKGLGKSNISIY--------------------------------------KVRT
A8AY02_STRGC          PSSNQFQKNMQIENLSIY--------------------------------------KVKT
C4ZA16_AGARV          ----KQNLVGLGKTKFIK--------------------------------------KYRY
Q73QW6_TREDE          SATIDILVKGKEKFKSLIIENQFEVILEILKLFSATRNVSDLQHIGGSKYSGVAKIGNKI
B0RZQ7_FINM2          AVDFTVIGLGTECGKP-----------------------------------------RIT
G4Q6A5_ACIIR          GCDLKSINGSAQAARIMI----------------------------------SADLTGLS
R5GJ26_9FIRM          GCDLTNIGGSKNTAIVKL----------------------------------NAVLSNL-
CAS9_STRP1            PAAFKYFDTTIDRKR-----------------------------------------YTST
CAS9_STRMU            PATFKFFDKNIDRKR-----------------------------------------YTST
CAS9B_STRTD           AADFEFLGVKIPRYRD----------------------------------------YTPS
CAS9_LISIN            PASFKFFETTIERKR-----------------------------------------YNNL
E6LI02_ENTI1          PADFEFFGEKIPRKR-----------------------------------------YVSI
A0A142LIG4_9PROT      -KGGQIEGIGIKTALAVQ--------------------------------------KYNV
Q7MRD3_WOLSU          PRKEFECDQGVKFALDVK--------------------------------------KYQI
U2LZE9_TRELE          CKDWIIATSDNMLEPCWK--------------------------------------PQKG
E1QW44_OLSUV          SVDLSLVGGAKHAAQMKF-----------------------------------DFNAKLN
A0A1B3SLT6_9MOLU      SESLEFCYLEKAKEPNKR-------------------------------------IYKAI
R7EW40_9BACT          TDTTAQIKEGDKEMKMFH-------------------------------------RIGSI
Q2RX87_RHORT          KATALYAQLSCPNINLNG---------------------------------DQGYCVQSA
I0AP30_IGNAJ          IASLILSYSASNGVGEFG-------------------------------------SQNIS
D1AUW6_STRM9          TIELELNKGNISKCLVVGFS--------------------------GGKIEISSVIGDAL
B2KB46_ELUMP          FTEITNNNIQIWFGNIIKSTG-------------------------------GQDDSFTI
F0RSV0_SPHGB          GSGYQIYFSNLAKSKKGQ------------------------------------DTSFTL
E9S7M7_RUMAL          KPCAKDKRVSITKKDIVI--------------------------------------KLAV
Q4A5I2_MYCS5          SSSLRAKIKLLNKMDKGK------------------------------------AVSMKK
Q7NAI2_MYCGA          LNDLIEIKNLIETEYKENVDSD------------------------PKKKKKASQILRSL
Q6KIQ7_MESM1          DEKPQKLEIKYILGKKIK-------------------------------------DQKQI
E6WZS9_NITSE          ATGIIKAHLDLDGHVRSY--------------------------------------EVFG
K1LM04_9FLAO          IADIIKKDVEFGSQNCYE---------------------------------------TVE
                                                                                  

Q5L8F8_BACFN          SKGLDTI-VKVRVNHIGQIVSVGEY----------------
F9YQX1_CAPCC          SAFFNDI-IKVRINHLGGIVSVGEY----------------
F0P0P2_WEEVC          GIMIKEICIKLKVDRLGNISKA-------------------
R7D4J2_9BACE          GEMIKEICLPLKIDRLGQIIEISTF----------------
G8XA12_FLACA          TRKMNHNQFTAFVEGIDFKVLPSGKFQKI------------
G2Z1C1_FLABF          TRKMNHNQFTAFVEGIDFKVLPSGKFEKI------------
B8I085_RUMCH          DILGNKSIVKGEPRRGMEKYNSFKSN---------------
N9W911_9CLOT          -----------------------------------------
B1GZM3_ENDTX          DVLGNYTEVKHEKRMPAYITRKDKKH---------------
CAS9_PASMU            DELGKNRQICRPQQRQPVR----------------------
F9QBH3_9PAST          -----------------------------------------
A9HKP2_GLUDA          DRFGRKSPVRKEVRTWHGEACISPTPPG-------------
I3TWJ0_TISMK          DRFGVRTEVKSEVRTWHGEVCTSPVPPD-------------
Q20XX4_RHOPB          DRLGRKFEIPREVRTWRGEACT-------------------
I7GTK8_9HELI          SVLGEVKRTQSYPRENISLASKAKK----------------
D3UFL8_HELM1          SVLGEVLEHKPRNRQNIALKTTPKHV---------------
A8LN05_DINSH          RPAIASGIRRVSVDEIGRLRDGGTRPI--------------
A1WH93_VEREI          DQLRKAKARQVTISPIGELRDPGFKG---------------
J6LE60_9RHOB          PLLKDRGCVAVRVDPIGVVTLRRSNV---------------
CAS9A_STRTD           DVLGNQHIIKNEGDKPKLDF---------------------
A8AY02_STRGC          DILGNKHFIKKEGDEPKLKFKK-------------------
C4ZA16_AGARV          DILGNKYSCSEEKFTSFC-----------------------
Q73QW6_TREDE          SSLDNCILIYQSITGIFEKRIDLLKV---------------
B0RZQ7_FINM2          NLPDNTYLVYKSITGIYEKRIRIK-----------------
G4Q6A5_ACIIR          KKYSDIRLVEQSASGLFVSKSQNLLEYL-------------
R5GJ26_9FIRM          KDFKSVRIIDQSPTGLYEKVSPNLLSL--------------
CAS9_STRP1            KEVLDATLIHQSITGLYETRIDLSQLGGD------------
CAS9_STRMU            TEILNATLIHQSITGLYETRIDLNKLGGD------------
CAS9B_STRTD           SLLKDATLIHQSVTGLYETRIDLAKLGEG------------
CAS9_LISIN            KELLNSTIIYQSITGLYESRKRLDD----------------
E6LI02_ENTI1          SEIIDAVFIHQSITGLYETRVRLTEV---------------
A0A142LIG4_9PROT      DVLGTTYAAPLEQRRGLA-----------------------
Q7MRD3_WOLSU          DPLGYYYEVKQEKRLGTIPQMRSAKKLVKK-----------
U2LZE9_TRELE          QNYISVNVLFGKRKAHSVTVNPIGRVFRK------------
E1QW44_OLSUV          NPASSFVLIDQSVTGMFERRTRIGL----------------
A0A1B3SLT6_9MOLU      KQMKNIKLITSNSTRTKIKIID-------------------
R7EW40_9BACT          QALLALNPRKVSVSILGEIDLENLTQS--------------
Q2RX87_RHORT          EGIRKEKIRTTSCTALGRLRLSKKAT---------------
I0AP30_IGNAJ          EYSVDDPPIRIKDVCIKIRVDRLGNVRPL------------
D1AUW6_STRM9          DLINDKISTRIKERYYITVSTIKSIKKINKNILGD------
B2KB46_ELUMP          NSMQQYNPRKLILSSCGFIKYRSPILKNKEG----------
F0RSV0_SPHGB          TTIKNYDVRKVQLSSAGLVRYVSPLLVDKIEKDEVALCGE-
E9S7M7_RUMAL          DLMGKVQGENNGKGISCGEPLSLLKEKN-------------
Q4A5I2_MYCS5          ITNPDEYKIIEHVNPLGINLNWTKKLENNN-----------
Q7NAI2_MYCGA          SVILNDYILLDAKYNFDILGLSKNKIDEILNSKLDLDKIAK
Q6KIQ7_MESM1          QKPVKKYFPNWKKVNLTYMGEIFKK----------------
E6WZS9_NITSE          TLPEGSIEWFKEESGYGRVEDDPHH----------------
K1LM04_9FLAO          GRSIKENCFKLEIDRLGNIVKVIKR----------------