CLUSTAL format seed alignment for MF_01520
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
ISPDF_DESPS -----------------------------------MKNGAVIIPAAGSGTRM------KL
ISPDF_ALBFT ----------------------MADTPALIPQSDTTPRCWALIPCAGTGSRA------GA
ISPDF_CAMJE -----------------------------------MSEMSLIMLAAGNSTRF------NT
ISPDF_CAMJR -----------------------------------MSEMSLIMLAAGNSTRF------NT
ISPDF_CAMJJ -----------------------------------MSEISLIMLAAGNSTRF------NT
ISPDF_CAMFF -----------------------------------MLDLSLIMLGAGNSTRF------GL
ISPDF_SULDN ----------------------MYNFVTLSILGAYLHTITLILLAAGSSSRF------EL
ISPDF_HELHP ---------------------------------MVLDNVSLIMMAAGDSTRFCASNAQTF
ISPDF_WOLSU -----------------------------------MSQVSLVVMGAGESSRF----RQGL
ISPDF_HELPY MSLIRVNGEAFKLSLESLEEDPFETKETLETL---IKQTSVVLLAAGESRRF------SQ
ISPDF_HELPH MSLIRVNGEAFKFSLESLEEDPFETKETLEIL---VKQTSVVLLAAGESRRF------SQ
ISPDF_HELPJ MSLIRVNGEAFKLSLESLEEDPFETKETLETLETLIKQTSVVLLAAGESKRF------SR
ISPDF_HELAH MSLIRVNGEAFNLSLESLKEDPFETKKTLETL---IKQTSVILLAAGESRRF------SQ
ISPDF_PELUB ------------------------------------MNSCFIILAGGESKRF------NS
ISPDF_DESVH ------------------------------------MRTWVLLLAAGSGTRL---ATAGL
ISPDF_DESVV ------------------------------------MRTWVLLLAAGSGTRL---ATAGL
ISPDF_OLEA2 ------------------------------------MHTWALLLAAGQSSRI---AAACP
ISPDF_LAWIP ------------------------------------METWALILAAGQGSRL---LST-I
ISPDF_WOLPM -------------------------------MCAKKYKIAALIVAAGVGSRC------NS
ISPDF_RHIEC ---------------------------MLQMPSKQPISAGIVVVAAGRGERAGS----ST
ISPDF_RHIJ3 ---------------------------MLQMPSKQPISAGIVIVAAGRGERAGS----SK
ISPDF_RHIME ------------------------------MQGEEQFSCGVVIVAAGRGERAGQ----SA
ISPDF_AGRFC -------------------------------MQESTMKFGIVIVAAGRGERAGS----PE
ISPDF_BARHE ------------------------------------MSIAAVILAAGRGKRAGS----LP
ISPDF_BARQU ------------------------------------------MLAAGRGKRAGS----LQ
ISPDF_BARBK ------------------------------------MSIAAIILAAGRGSRAGS----LQ
ISPDF_BRUAB -------------------------------------------MAAGRGERAGQ----SA
ISPDF_BRUA2 -------------------------------------------MAAGRGERAGQ----SA
ISPDF_BRUME -------------------------------------------MAAGRGERAGQ----SA
ISPDF_BRUSU -------------------------------------------MAAGRGERAGQ----SA
ISPDF_RHILO -------------------------MTEASENASATGGVAVVIVAAGRGARAGQ----AN
ISPDF_CHESB -------------------------MNAPFEKDRRNRRVAVVVVAAGRGERAGQ----AQ
ISPDF_BRASB --------------------------------MTISQRTAAILVAAGRGLRAG------T
ISPDF_BRASO --------------------------------MTTSQRTAAILVAAGRGLRAG------A
ISPDF_BRADU --------------------------------MAKSQRTAVVLVAAGRGLRAG------A
ISPDF_NITHX --------------------------------MPTSKRTAAIIVAAGRGLRAG------T
ISPDF_NITWN --------------------------------MPSSKRTAAIIVAAGRGLRAG------A
ISPDF_RHOPS --------------------------------MPNPPRTAAIIVAAGRGLRAG------A
ISPDF_RHOP2 --------------------------------MQKPPRTAAIIVAAGRGLRAG------A
ISPDF_RHOPA --------------------------------MTNSPRTAAIIVAAGRGLRAG------A
ISPDF_RHOP5 --------------------------------MANSRRTAAIIVAGGRGLRAG------G
ISPDF_RHOPB --------------------------------MSNSKRTAAIIVAGGRGLRAG------A
ISPDF_GLUOX ------------------------------------MRIAALLLAAGRGRRFDASSQSGE
ISPDF_GRABC ------------------------------------MRIAAILVAGGSGSRF------GS
ISPDF_PARDP --------------------------------MTIPATYAAIITAAGRGTRA------GD
ISPDF_RHOCB ------------------------------------MTVAVIIVAAGRGTRA------GE
ISPDF_RUEPO ------------------------------------MTTAAIIVAAGRGTRA------GG
ISPDF_RUEST ------------------------------------MTLAVLIVAAGKGTRA------GG
ISPDF_JANSC -------------------------------MEKPAQRATAIIVAAGRGIRA------GG
ISPDF_ERYLH ---------------------------MATPSPLP--SFAAIVVAAGKGLRA------GQ
ISPDF_NOVAD ---------------------------MNSVPSLPGQSVAAVVVAGGKGLRT------GG
ISPDF_SPHAL ---------------------------MTESAAPSPRCVAAILLAGGRGLRA------GF
ISPDF_ZYMMO ---------------------------------MKRTDNIALIVAAGQGKRA------GE
ISPDF_CAUVC ------------------------------------MTFSVVIVAAGSGTRA------GP
ISPDF_HYPNA -----------------------------------MTETVAIIVAGGRGQRA------GA
ISPDF_MAGSA -----------------------------------MAKTVVLVVAAGRGRRF------GG
ISPDF_RHORT -----------------------------------MAKVAALIVAAGRGKRF------GG
ISPDF_MARMM ------------------------------------MKIAAVIVAAGRGERA------GG
ISPDF_ANADE --------------------------------MIRGERVIGILAAGGSGQRA--------
ISPDF_TROW8 ------------------------------------MAVGLLLLAAGVGSRL------SS
ISPDF_TROWT ------------------------------------MAVGLLLLAAGVGSRL------SS
.* . *
ISPDF_DESPS DYPKQYHAVAGTPIIVHTIRAFNKHPCIAKIILVVPQDHLEESKALLQKYQLE-----NI
ISPDF_ALBFT TGPKQYQLLAGKPMVLHTLAAFAAVPRIARTLVVVAPDDAFFASQTLTDARF-------L
ISPDF_CAMJE KVKKQFLRLGNDPLWLYATKNLSSFYPFKKIVVTSS--NITYMKKFTKN----------Y
ISPDF_CAMJR KVKKQFLRLGNDPLWLYATKNLSSFYPFKKIVVTSS--NITYMKKFTKN----------Y
ISPDF_CAMJJ KVKKQFLRLGNDPLWLYATKNLSSFYPFKKIVVTSS--NISYMKKFTKN----------Y
ISPDF_CAMFF QSKKQWLRTGDDPLWLYATKNISSNYLFKDVIVVSN--ECEYMRKFSSH----------F
ISPDF_SULDN DIKKQWLRVGDRPLWHFVADRCEKTGYFDKIIITSSLDDIEFMKNYA-D----------Y
ISPDF_HELHP RCKKQWLRVGEEPLWLVATRNLTHHFSFKQVILTASSKDYVYMQNISP-----------Y
ISPDF_WOLSU SIKKQWLRLGETPLWKHVALHLSKQACFDQVIITASPKEVKYMQKQVD-----------F
ISPDF_HELPY TIKKQWLRSNHTPLWLSVYESFKEALDFKEIILVVSELDYIYIKRHYPE----------I
ISPDF_HELPH TIKKQWLRSNHTPLWLSVYESFKEALDFKEIVLVVSELDYIYIQRHYPE----------I
ISPDF_HELPJ AIKKQWLRSHHTPLWLSVYESFKEALDFKEVILVVSELDYVYIQRHYPK----------I
ISPDF_HELAH TIKKQWLRSNHTPLWLSVYESFTEALDFKEVILVVSELDYTYIKRHYPK----------I
ISPDF_PELUB NTPKPYTNYKGKPLLLHSIDKAKVFNKFNKIVLVVNKKHKNFIKKLNIKN---------I
ISPDF_DESVH PDAKQFLPLHGAPLYWASARTMAHVAGIEGIVFVFPPHRVEEERARISALDDGSVLGLDW
ISPDF_DESVV PDAKQFLPLHGAPLYWASARTMAHVAGIEGIVFVFPPHRVEEERARISALDDGSVLGLDW
ISPDF_OLEA2 GVRKQFLLWQNAPLFWHSAVMLSRVSRMRGIIFVFPEDMLEEATAMVRELDAGRALGIPW
ISPDF_LAWIP GIAKQFFVWKGIPLYWQSVLQFMHCARIRGVVLVFPSEVKDNEEKVVDRLAAQYDLRLPY
ISPDF_WOLPM TIPKQYIKLAGKSVLFHTIKRFLANQYIDYIRIAINRDHESFYEKAISLITDTKL----L
ISPDF_RHIEC EGPKQYRMIGGKPVIVHTLENFMTWEAAKQIVVVIHPDDEALFAKASRHIIS----ETPI
ISPDF_RHIJ3 EGPKQYRMIGGKPVIVHTLENFMTWEAATEIVVVIHPDDEALFARAFRHIIS----ATPI
ISPDF_RHIME EGPKQYRTIGDRPVIAHTLDIFATWPGAGPVVVVIHPDDEELFAAARKRMAG----ALEL
ISPDF_AGRFC EGPKQYRPIGGRAVIEHTLATFLRWNDACPIVVVSHADDAALLSPILARLDA----GERI
ISPDF_BARHE KKPKQYRLLGQEPVICHTVRCFCQNPAITTIILVIHPEDRQICEQAIADF------KEQL
ISPDF_BARQU KNPKQYRLLGQKPVICHTVRCFCQHPAITTIILVIHPEDRQICEQAITDF------KEHL
ISPDF_BARBK NGPKQYRFLGREPVICHTIRCFLQHPAITNIILVIHPDDYQICANAIADL------KDHL
ISPDF_BRUAB EGPKQYRLIGAEAVLARTLRAFTDCPLIGTIAVVIHPDDHALYRRAVPEK------HENV
ISPDF_BRUA2 EGPKQYRLIGAEAVLARTLRAFTDCPLIGTIAVVIHPDDHALYRRAVPEK------HENV
ISPDF_BRUME EGPKQYRLIGAEAVLARTLRAFTDCPLIGTIAVVIHPDDHALYRRAVPEK------HENV
ISPDF_BRUSU EGPKQYRLIGAEAVLARTLRAFTDCPLIGTIAVVIHPDDHALYRRAVPEK------HENV
ISPDF_RHILO -GPKQYQNIGGRAVIAHTLEIFLAHPRTDRIVVAIHADDHELFRQAAGSQ------AERV
ISPDF_CHESB NGPKQYRLIGGKPVIRHTLEVLAKSKRVGTIAVAVHPEDSSLFNQAREGL------DGDI
ISPDF_BRASB GGPKQYRAIGGRTVIHRALAAFSEHPDVAVVQPVVNPDDIDVFNAAVSGL-------RHE
ISPDF_BRASO GGPKQYRTIGGRTVIHRALAAFAEHPEVAVVQPVVNPDDIDVFNAAVAGL-------RHE
ISPDF_BRADU GGPKQYREIGGQPVIYRAMEAFSRHPDVFAVQPVVNPDDSAMFTAAVAGL-------KHE
ISPDF_NITHX GGPKQYRTIAGRTVIARAMEAFCDHPDVFAVQPVLNPDDLAMFNQAVAGF-------RYR
ISPDF_NITWN GGPKQYRTIGGRTVISRAMEAFCQHPDVFAVQPVLNPDDLSMFNQAAAQF-------RYR
ISPDF_RHOPS GGPKQYRTLAGRPVIARALQPFCTHPEVFAVQPVTNPDDTAIFNDAVTGL-------NFR
ISPDF_RHOP2 GGPKQYRTLAGRPVIARALQPFCTHPEVFAVQPVTNPDDTATFNEAVAGL-------DFR
ISPDF_RHOPA GGPKQYRSLAGRPVIARAMEPFCTHPGVMAVQPVTNPDDTEMFNAAVAGL-------NFR
ISPDF_RHOP5 GGPKQYRTLAGQPVIYRSMQPFCTHPDVFAVQPVTSPDDIALFEQAVAGL-------THR
ISPDF_RHOPB GGPKQYRSLAGQPVIFRAMQPFCTHAEIFAVQPVTSPDDAEMFKLAVAGL-------NYQ
ISPDF_GLUOX NSSKQFRMLRGKPVIRRAAEAL----LPHVDVLLPVGDDPLLADSLEGLDI--------L
ISPDF_GRABC DIPKQFLPVGGKPLIRHGAERL----SAKVDLLQPVGCADDIAPLLQGLDH--------L
ISPDF_PARDP GPPKQWRPLAGQSVLERSIAAF--AGFPR-VVVTLAPEDMARGVAELSGP---------V
ISPDF_RHOCB GLPKQWRDLAGRPVLAQTVAAF--AGLGR-ILVVLHPDDMGLGMDLLGGS---------V
ISPDF_RUEPO GVPKQWRPLAGRRVADWTLDRFALRQITH-VVLVLHPEDHDAWDEFATTP---------L
ISPDF_RUEST GLAKQWRPLAGRLVIDWTIEAFQRAGCGT-IMVVRDPDNEHAIEALAPYPE--------L
ISPDF_JANSC GEPKQWRRIAGRSIVEWSVNRFAAHHAGFDVVLVIHPDDEWRLNGLDLPTT--------L
ISPDF_ERYLH PVPKQFATWRGKPVLRHSVESLRA-AGADPIVVAIPDHAGDVAAKALDGI-------TEV
ISPDF_NOVAD PVPKQFVIWRGKPLLRHCVEALEA-AGIAPIVVAIPAGWDEAATQALAGI-------SMV
ISPDF_SPHAL GRPKQLEWLCGKPVLRWSLDVL---AGYPGLSGGVLVANHDVMAATYPLP-------EGW
ISPDF_ZYMMO GLPKQYRQIAGKAILAHAIDNLLAHPEIDTVQVVIADGHQTLYQEAVGDR-------DLP
ISPDF_CAUVC GQAKQWRVLAGRPVLRWSVEAFLA-AGAAEVVVVTTADGEAFLPRMLEGL-------QGW
ISPDF_HYPNA ERPKQWQMLLGKRVIDWSIAAFVDHPQISQVVIVAGDELGDCSAEPK------------I
ISPDF_MAGSA DLPKQYHDLAGRMVLRHTLAAFATNPEIGAVRAVIHPDDRQLYDMAAAGL-------NLL
ISPDF_RHORT DLPKQYQTLGGRPILRHTLARFAAHPDVALVRAIIHPEDRDLYGAAAHGLA------TLL
ISPDF_MARMM GVPKQYRRLGGFFVLTHTLLRLLHREVFDSIIVVVNPADADHIAAVEAELD------IKL
ISPDF_ANADE GVAKQWLVLGGESVLRRSARVLAACDAVDGLVVVVPPGDEARGEAELAGLG------KPV
ISPDF_TROW8 SLPKAFVSVGGLDLIQWCLKNLGQLRTALEVVVTVPKGFVELCERNVLQSLGT---LEKI
ISPDF_TROWT SLPKAFVSVGGLDLIQWCLKNLGQLRTALEVVVTVPKGFVELCERNVLQSLGT---LEKI
* :
ISPDF_DESPS SIVTGGARRQDSVLRGLQ-----EVPESIDIVLVHDGARPMVSAELISRCYKGAQQY--G
ISPDF_ALBFT VAACGGSTRAASVLNGLNFLLG-QGAARHDWVLVHDAARCLIRPDQIDQLIDACWQD--D
ISPDF_CAMJE EFIEGGDTRAESLKKALELIDS-------EFVMVSDVARVLVSKNLFDRLIENLDKA---
ISPDF_CAMJR EFIEGGDTRAESLKKALELIDS-------EFVMVSDVARVLVSKNLFDRLIENLDKA---
ISPDF_CAMJJ EFIEGGDTRAESLKKALELIDS-------EFVMVSDVARVLVSKNLFDRLIENLDKA---
ISPDF_CAMFF KFIKGGETRQDSLRNAISNINS-------EFVMVSDIARADIPKELITKLIESAHNA---
ISPDF_SULDN TFVEGGQTRQQSLKNSLLHVDT-------EYVLVSDVARSCIDEAFLKKIISHVGKS---
ISPDF_HELHP KVVQGGQTRCQSLRNALKYVDT-------PLVLVSDVARWDSSDSIIKTMLKALDESV--
ISPDF_WOLSU EVIEGGGTRQESLQNALASVKT-------PWVLVSDVARFDVPSEVISRVIGRLGEA---
ISPDF_HELPY KLVKGGASRQESVRNALKIIDS-------AYTLTSDVARGLANIEALKNLFLTLQQTS--
ISPDF_HELPH KLIKGGASRQESVRNALKIIDS-------AYTLTSDVARGLANMETLKSLFLTLQQTS--
ISPDF_HELPJ KLVKGGASRQESVRNALKVIDS-------TYTITSDVARGLANMEALKSLFLTLQQTS--
ISPDF_HELAH KLVRGGISRQESVCNALKVISG-------AYTLTSDVARGLANIEMLNDLFLTLQNTN--
ISPDF_PELUB RIITGGKTRAESAYNALKSIKENN----FKNVIIHDAARPNFSLKLLNKLMNELKLN---
ISPDF_DESVH HVVGGGAARQDSVACGLAALPRS-----CEAVLVHDAARPFASPALVARVLSALHDGH--
ISPDF_DESVV HVVGGGAARQDSVACGLAALPRS-----CEAVLVHDAARPFASPALVARVLSALHDGH--
ISPDF_OLEA2 KAVSGGARRQDSVASGLGQLPAE-----CDTVLVHDAARPFASASLTNSILDALQAGA--
ISPDF_LAWIP IVISGGKLRQDSVKNALNTLPKN-----CSHVLIHDAARPFISPKLINNVIEVLEAGA--
ISPDF_WOLPM SPVYGGENRQSSVKLGLESLQKIN----PDFVVIHDACRPFVSDVLIDNLVESMINDQ--
ISPDF_RHIEC ETVHGGATRQESVLAGLRYLK----DKHVSHVLIHDAVRPFFDHVLLDRIAERLGNGA--
ISPDF_RHIJ3 ETVHGGATRQQSVLAGLRYLK----DKQISHVLIHDAVRPFFDHALLDRIAESLDAGA--
ISPDF_RHIME TVVHGGATRQLSVLAGLEAVA----ATGVEYVMIHDAVRPFFDHTLLDRCGAALRDGA--
ISPDF_AGRFC TTVTGGATRQQSVLAGLEALS----SHGLTHVMIHDAVRPFVAADMLERIAALHRAGA--
ISPDF_BARHE IIVEGGNTRQKSTLRGLQALR----KFKPKYVHIHDGARPFVENKLLEQIHTTVTPQE--
ISPDF_BARQU IIVEGGNTRQISTLRGLHALK----KFKPKYVHIHDGARPFIENKLLEKIHTTVNHQE--
ISPDF_BARBK TIIEGGETRQISTLQGLRALK----NVKPNYVHIHDGARPFIGNELLEQIHTSINHKE--
ISPDF_BRUAB ILVTGGPTRQESTRLGLLALK----DEAPQYVLIHDGVRPFIGQDLLERIIANLTPDN--
ISPDF_BRUA2 ILVTGGPTRQESTRLGLLALK----DEAPQYVLIHDGVRPFIGQDLLERIIANLTPDN--
ISPDF_BRUME ILVTGGPTRQESTRLGLLALK----DEAPQYVLIHDGVRPFIGQDLLERIIANLTPDN--
ISPDF_BRUSU ILVTGGPTRQESTRLGLLALK----DEAPQYVLIHDGVRPFIGQDLLERIIANLTPDN--
ISPDF_RHILO TAIIGGPTRQESVRLGLLALK----EHAPGQVLIHDAVRPFVDADLIDRTISAIGENE--
ISPDF_CHESB RAVHGGASRQESTRLALAALE----EVKPDIVLIHDGVRPFIDEALIERVIEAVGEDS--
ISPDF_BRASB VPAHGGATRQASVLAGLEALV----PHRPDIVLIHDAARPFVTSAVISRAIQAAGKTG--
ISPDF_BRASO APARGGATRQASVLAGLEALV----PHKPEIVLIHDAARPFVTPAVISRAIIAANKTG--
ISPDF_BRADU PPTNGGATRQASVLAGLEALA----KHQPDIVLIHDAARPFVSDGVISRAIDAASRTG--
ISPDF_NITHX PPANGGATRQASVHAGLEALA----ADAPDIVLIHDAARPFATPALIRRAIEATDITG--
ISPDF_NITWN PPANGGATRQASVRAGLEALA----ADAPDIVLIHDAARPFVTPALITRAIDAADKAG--
ISPDF_RHOPS PAVGGGATRQGSVRAGLEALA----ELNPDIVLIHDAARPFVTPDLISRAIVAAGQTG--
ISPDF_RHOP2 PAVGGGATRQASVRAGLEALA----ELNPDIVLIHDAARPFVTPDLISRAIVAAGQTG--
ISPDF_RHOPA PAVGGGATRQASVRAGLEALA----ELKPDIVLIHDAARCFVTPELISRAITAAGATG--
ISPDF_RHOP5 PPANGGATRQQSVYSGLEALA----KDAPDIVLIHDAARAFVDAALISRAIVAAQRTG--
ISPDF_RHOPB PPAPGGATRQGSVRAGLEALA----ADAPDIVLIHDAARPFVDAALISRAIVAAQITG--
ISPDF_GLUOX PPVSGGAERHDSVRNGLEALAK--LPEPPDLVLVHDGARPCVPAEVVQNVINALKT--HE
ISPDF_GRABC PIVDGGKERQDSVRAGLEAL----VPYAPDIVLIHDAARPYFPDHTIEDLIEALQI--HD
ISPDF_PARDP VLVAGGATRSDSVRAALESLE----GSGVTHVLIHDGARPLVSRRVIGGVIEALQSG-AP
ISPDF_RHOCB VLVAGGSTRSESVKNALEALE----GSDVTRVLIHDGARPLVPASVTAAVLAALET--TP
ISPDF_RUEPO ILAPGGSDRAGSVRNGLAALD----GLGITKVLIHDVARPCVSAATIGAVLDALDA--HP
ISPDF_RUEST LLADGGPSRSESVRNGLIALQ----EIGVERVLIHDAARPCVCPQVIQQVLDALDD--TP
ISPDF_JANSC RVVHGGDSRAASVKAGLAVC------CDAGHVLIHDVARPCVSLAVIQSVLDATRA--GG
ISPDF_ERYLH VFVTGGQTRQDSVRAALERLS---SVPP-ERVLIHDAARAILPTPVIERVLHGLDES--G
ISPDF_NOVAD RLVHGGATRQESVKAALEVLE---GDAP-ARVLIHDAARPDLPGSVIERLLTALDKR--T
ISPDF_SPHAL MAADPGVERQQSVANALSALT---DWPDDAVVLVHDAARPGVDSAVVDRLLAALDGA--D
ISPDF_ZYMMO QPVIGGVFRRDSVINGLKAAH---DRGY-KRVLIHDAARPFLPKTVIDRLLDALKSS--K
ISPDF_CAUVC RSTLGGATRALSVQAGLAALS---ERPGAEPVMIHDAARPFVSRNVILALLGALSDA--D
ISPDF_HYPNA IQAKPGNTRTQSVLSGLAAAT---ISED-ATVVIHDAARPGIDAATISSLIARLQDPSVS
ISPDF_MAGSA EPVHGGATRQDSVRLGLDSLK---DLNP-DKVLIHDGARPFIDHGTIGRVIRALDRH--P
ISPDF_RHORT DAVEGGAERQDSVRLGLESLT---DVAP-DYVLIHDGARPLVDGALIDRVIAALADH--P
ISPDF_MARMM DTVPGGATRTASVRAGLERAR---DLGL-DAVMIHDAARPFLGDALIDRLVKALADH--P
ISPDF_ANADE RAVAGGPARADSVRNGLAAADG-------AVVLVHDAARPFASAALAGRVAEAAARDGAA
ISPDF_TROW8 KIVTGGATRQDSVGLGIRYFSA-----RITKLLVHDVARAFTPPEIYLSVIKQLETSK--
ISPDF_TROWT KIVTGGATRQDSVGLGIRYFSA-----RITKLLVHDVARAFTPPEIYLSVIKQLETSK--
* * * .: * *
ISPDF_DESPS AV-IAAVPVKDTLKRG-AGRIVTGTV---------------DREGLWQAQTPQAARKALL
ISPDF_ALBFT VGGLLALPLPDTLKRE-SLGRVAATL---------------ERADKWLAQTPQMFRLGSL
ISPDF_CAMJE -DCITPALKVADTT-----LFDNEAL---------------QREKIKLIQTPQISKTKLL
ISPDF_CAMJR -DCITPALKVADTT-----LFDNEAL---------------QREKIKLIQTPQISKTKLL
ISPDF_CAMJJ -DCITPALKVADTT-----LFDNEAL---------------QREKIKLIQTPQISKTKLL
ISPDF_CAMFF -DCIVPALKISDSV-----IYQNEYI---------------NRDELKLIQTPQLSRTNML
ISPDF_SULDN -DAVVPYLNITDTI-----VYDDKTI---------------DRERVKRVQTPQLSLTTAL
ISPDF_HELHP -ACVVPFVGVADTS-----FYEGEYL---------------KRESIKLIQTPQLSRVEDL
ISPDF_WOLSU -ECVAPAIGVSDTV-----SYQGEYL---------------SRSEVKLIQTPQLSHVESL
ISPDF_HELPY HYCIAPYLPCYDTA-----IYYNEAL---------------DREAIKLIQTPQLSHTKAL
ISPDF_HELPH HYCIAPYLPCYDTA-----IYYNEAL---------------DREAIKLIQTPQLSHTKTL
ISPDF_HELPJ HYCIAPYLPCYDTA-----IYYNEAL---------------DREAIKLIQTPQLSHTKTL
ISPDF_HELAH HYCIAPYLPCYDTA-----IYYNEAL---------------DREAIKLIQTPQLSHTKTL
ISPDF_PELUB -DCVIPAIQTADTVK-QKISNNVKNL---------------KRENIYLIQTPQAFNYKKL
ISPDF_DESVH AGVVPGIPLTDTVKE-TTDGFVANTP---------------DRSRLVAVQTPQGFTLKAL
ISPDF_DESVV AGVVPGIPLTDTVKE-TTDGFVANTP---------------DRSRLVAVQTPQGFTLKAL
ISPDF_OLEA2 EGVVPALAVTDTIKV-VEDGAVLSTP---------------DRTKLVAVQTPQGFSLQAL
ISPDF_LAWIP VGVVPGISVTDTIKQ-VIQGEVIVTR---------------PREQLIAVQTPQGFHLKTI
ISPDF_WOLPM YTGVVPAIEVEDTMSLVSNSFIESTI---------------SRGKLRAIQTPQIFNFKEL
ISPDF_RHIEC PAVLPAMPVTDTLKRADSAGTISATV---------------SREHLYAAQTPQSFVFETI
ISPDF_RHIJ3 QAVLPAIPVTDTLKRADNAGTVLTTV---------------SREHLYAAQTPQSFAFETI
ISPDF_RHIME QALLPAIAVADTLKRTKAAGLVAETV---------------PRTDLYAAQTPQCFRLEPI
ISPDF_AGRFC GGVLPALPVTDTLKRG-LEDRVVETV---------------SRQGLYAAQTPQSFSYSDI
ISPDF_BARHE -GVLPVLAVCDTLKRINSTHHVLETI---------------PRTHLYSAQTPQCFPFERI
ISPDF_BARQU -GVLPVLPVSDTLKRVNSTHRVLETI---------------PHTHLYSAQTPQCFPFERI
ISPDF_BARBK -GILPVLSVSDTLKYVSNTHHVLETI---------------PRTNLYRAQTPQCFPFELI
ISPDF_BRUAB -GVLPALAVSDTLKRAAADGMVETTI---------------SRTGLFAAQTPQAFPYAPI
ISPDF_BRUA2 -GVLPALAVSDTLKRAAADGMVETTI---------------SRTGLFAAQTPQAFPYAPI
ISPDF_BRUME -GVLPALAVSDTLKRAAADGMVETTI---------------SRTGLFAAQTPQAFPYAPI
ISPDF_BRUSU -GVLPALAVPDTLKRAAADGMVETTI---------------SRTGLFAAQTPQAFPYAPI
ISPDF_RHILO -GALPALPVADTLKRESAAGVVAETV---------------SRSGLHAAQTPQGFPYGPI
ISPDF_CHESB -GALPALPVSDTLKRSGVNGIITGTV---------------PRDGLFAAQTPQGFPFRPI
ISPDF_BRASB -AAIPVVPVTDTIKEVTASGDIIATP---------------ERAKLRIAQTPQTFKFEVI
ISPDF_BRASO -AAIPVAPVTDTIKEVGASGDITATP---------------ERAKLRIAQTPQTFRFDTI
ISPDF_BRADU -AAIPVVPVTDTIKLTGASGNVEDTP---------------DRARLRIAQTPQSFRFDVI
ISPDF_NITHX -AAVPVIPVTDTIKQVDASGAVNATP---------------DRAKLRIAQTPQAFRFDVI
ISPDF_NITWN -AAVPAIAVTDTIKQVDESGAVNATP---------------DRAKLRIAQTPQAFHFDMI
ISPDF_RHOPS -AALPVVAINDTVKQINAEGCVEATP---------------DRARLRIAQTPQAFRFDVI
ISPDF_RHOP2 -AALPVIAVNDTVKQVDAEGCVVATP---------------DRAQLRIAQTPQAFRFDVI
ISPDF_RHOPA -AALPVVPVTDTIKQVDSSGAVDATP---------------DRASLRIAQTPQAFRFDVI
ISPDF_RHOP5 -AAVPTIPVTDTIKQVNGTNDVEATP---------------DRATLRIAQTPQAFRYDVI
ISPDF_RHOPB -AAVPTIAVTDTIKQINAQGDVVATP---------------DRARLRIAQTPQAFRFDVI
ISPDF_GLUOX -GVIPAVAVIDTIKKA-KDGIIVDTV---------------PRDGLWRAQTPQGFRFGTL
ISPDF_GRABC -GAIPAVPVADTLKRA-AGNIIDSTV---------------PREGLYRAQTPQAFKFSVL
ISPDF_PARDP -AAAPALPVTDALWRA-QDGCVTATA---------------SREGLFRAQTPQGFALDAI
ISPDF_RHOCB -GAAPALAVTDALWRG-EAGLVAGTQ---------------DREGLYRAQTPQGFRFPEI
ISPDF_RUEPO -GAAPGLAVTDALWTG-AEGLVTGTR---------------ERDGLFAAQTPQGFRYDAI
ISPDF_RUEST -AAAPGLAVTDALWTG-ADGHVTGTQ---------------DRSALFAAQTPQGFHFDAI
ISPDF_JANSC -AAAPALPVTDALWRG--DTHVSGTQ---------------NRDGLWRAQTPQGFDVSAI
ISPDF_ERYLH -GAIPVLPVVDSLAVA-AGERMADKA---------------DRESLRRVQTPQGFRFSDI
ISPDF_NOVAD -GAIPVLPVVDSMVRG-SGDAMGETV---------------AREDLYRVQTPQAFHYPAI
ISPDF_SPHAL -AAIPVLPVPDTLVEA-ADGAAGAVV---------------ARDRLARVQTPQAFRLGTL
ISPDF_ZYMMO -AAIPVLPVVDTLV-----NQEVEAV---------------DRNLFHRVQTPQAFDLETV
ISPDF_CAUVC -LALPALAVADTLKRQ-PTGEAAQTV---------------SREHLWRAQTPQAARRDTL
ISPDF_HYPNA -GAAPAMPVADALKTN-S-GQSWTNV---------------DRTGLVRVQTPQAFRLGEI
ISPDF_MAGSA -GALPVVPVADTLKRG-QDGFVADTV---------------DRANLFRAQTPQGFRYAEI
ISPDF_RHORT -GAIPALAVADTLKRG-AGGMIGQTV---------------DRAGLWRAQTPQGFRYDAI
ISPDF_MARMM -AVIPALPVADALFRG-GDARMGDPV---------------SRDGLYAAQTPQAFHLAPL
ISPDF_ANADE LAALPATDTVKRAEAGAEVPRVLETL---------------DRRTVWLAQTPQGFRRAVL
ISPDF_TROW8 -AVIPVIAIVDSIKKVNMQDAYREVARGPGEPFHTKSVLHLDRREFFSAQTPQGFDRALL
ISPDF_TROWT -AVIPVIAIVDSIKKVNMQDAYREVARGPGEPFHTKSVLHLDRREFFSAQTPQGFDRALL
: **** :
ISPDF_DESPS VKAFKE---NGMRNVTDESTLLEGVGIPVTLIEGSETNIKITRPEDLILAENFLRE----
ISPDF_ALBFT LDALQV---AGT-TVTDESSAMEAMGLSPKLVPGSAQNFKVTYPQDFCLAEAVLMTRSSG
ISPDF_CAMJE KKALDQ----NLEFTDDSTAIAAM-GGKIWFVEGEENARKLTFKEDLKK-LD-LPTP---
ISPDF_CAMJR KKALDQ----NLEFTDDSTAIAAM-GGKIWFVEGEENARKLTFKEDLKK-LN-LPTP---
ISPDF_CAMJJ KKALDQ----NLEFTDDSTAIAAM-GGKIWFVEGEENARKLTFKEDLKK-LD-LPTP---
ISPDF_CAMFF KKALKT----DNIFTDDSSAIKAI-GGTVWYIEGDERAKKLTYKDDLKR-LN-LNSP---
ISPDF_SULDN KSALLR----EEEFTDESSAIVAN-GGSREFILGQESAHKITHIEDLKK-LSCLSAP---
ISPDF_HELHP QEALKDT---SKDFSDESSALYAL-GKKIAFVQGSELMNKLTFSSDLKAHITRLSPP---
ISPDF_WOLSU LLAFRQ-----GDFTDESSAIAKS-GGRVLLVEGSERLKKLTHPHELTL-LQGFEPP---
ISPDF_HELPY QSALNQ-----GDFKDESSAILQAFPDRVSYIEGSKDLHKLTTSGDLKH-FTLFFNP---
ISPDF_HELPH QSALNQ-----GDFKDESSAILQAFPNSVSYIEGSKDLHKLTTSDDLKH-FAFFFNP---
ISPDF_HELPJ QSALNQ-----GGFKDESSAILQAFPNSVSYIEGSKDLHKLTTSGDLKF-FTPFFNP---
ISPDF_HELAH QLALNQ-----GDFKDESSAILQAFPDLVSYIEGSKDLHKLTTSDDLKI-FTPFFNP---
ISPDF_PELUB FELQNNK---SEEVTDDANLFVRA-GKKIKIIKGETTNNKITINSDIKF-----------
ISPDF_DESVH STAHETARTAGWNVTDDAALLERCGIPVRI-VAGEVVNAKITTPEDLAMLDANEPQ----
ISPDF_DESVV STAHETARTAGWNVTDDAALLERCGIPVRI-VAGEVVNAKITTPEDLAMLDANEPQ----
ISPDF_OLEA2 LGAHRHCAEKALAVTDDASMLELLGQHTVITVEGEASNIKVTHPEDLTMLHSSEKKN---
ISPDF_LAWIP VEGHNRATLEKWTVTDDASLLELCGHTVQV-INGEIENRKISFPQDLLYMVE-QPK----
ISPDF_WOLPM LSCHQSV----KEFTDDSSLMVEH-KKHVAIIKGEKSNFKLTTKEDINM--AKLLFE---
ISPDF_RHIEC LDAHEKAAASGRSDFTDDASIAEWSGIPVTVVEGTPDNVKLTLRSDIAMADDKLSAP---
ISPDF_RHIJ3 LEAHEKAAASGRSDFTDDASIAEWLGIPVTIVEGTADNVKLTVKDDIAMADDKLSAS---
ISPDF_RHIME LSAHRRAAASGRSDFTDDASIAEWAGIPVLLVEGAVDNFKLTLRRDLSMADEKLTRM---
ISPDF_AGRFC LDAHRAAAASGKTDFTDDASIAEWTGLTVTLTEGSVDNVKLTLKRDIAMADEKLSH----
ISPDF_BARHE LAAHEKAIKTCKKEFTDDSAIAEWFGISMRTIPGSPHNIKITWHEDLNTAHLYLQKKM--
ISPDF_BARQU LAAHERAMQTCKKEFTDDSAIAEWFGIPMHTIPGDSHNIKITWHEDFDTAHLYLKKKM--
ISPDF_BARBK LAAHEKAMQSHKQDFTDDSAIAEWFGIPIRTIPGDPNNIKITWPADLETARSYLLKGM--
ISPDF_BRUAB LDAHEKAFAINRTDFTDDAAIAEWQEIAVRIIEGSADNTKLTWAKDIEMADKRLRQDH--
ISPDF_BRUA2 LDAHEKAFAINRTDFTDDAAIAEWQEIAVRIIEGSADNTKLTWAKDIEMADKRLRQDH--
ISPDF_BRUME LDAHEKAFAINRTDFTDDAAIAEWQEIAVRIIEGSADNTKLTWAKDIEMADKRLRQDH--
ISPDF_BRUSU LDAHEKAFAINRTDFTDDAAIAEWQEIAVRIIEGSADNTKLTWAKDIEMADKRLRQDH--
ISPDF_RHILO LAAHDKAFQLGRLDFTDDAAIAEWAHIPVKLVPGSPDNVKLTWARDIAMAHQRLSSER--
ISPDF_CHESB YEAHQKAWQSGRSDFTDDAAIAEWAGISVRLVSGSPDNVKLTWAKDIALADQRLGPAM--
ISPDF_BRASB LEAHRRAARDGLTEFTDDAAIAEWAGLTVATFEGDVANMKLTTPEDFVREEARLAAQ---
ISPDF_BRASO LEAHRRAAREGLTEFTDDAAIAEWAGLTVATFEGDVANMKLTTPEDFVREEARLAAS---
ISPDF_BRADU LEAHRRAAKDGRSDFTDDAAIAEWAGLTVATFEGDVANMKLTTPEDFVREEARLAAQ---
ISPDF_NITHX LDAHRRAARDGRDDFTDDAALAEWVGLTVATFEGDAANMKLTTPEDFVREEARLAAM---
ISPDF_NITWN LDAHRRAAREGRDDFTDDAALAEWVGLTVATFEGDAANMKLTTPEDFVREEARLAAA---
ISPDF_RHOPS LDAHRRAARDGRDDFTDDAAIAEWAGLTVSTFEGDAANMKLTTPDDFIREESRLTAL---
ISPDF_RHOP2 LDAHRRAARDGRDDFTDDAAIAEWAGLTVSTFEGDAANMKLTTPEDFSREESRLTAA---
ISPDF_RHOPA LDAHRRAASGGRDDFTDDAAIAEWAGLTVSTFEGDANNMKMTTPEDFAREESRLMAA---
ISPDF_RHOP5 LEAHRRAAREGRDDFTDDAAIAEWAGLTVATFEGDAANMKLTTPEDFVREESRLAAL---
ISPDF_RHOPB LEAHRRAAREGRDDFTDDAAIAEWAGLTVATFEGDVANMKLTTPEDFVREESRLGAL---
ISPDF_GLUOX LELHRTHRDAR----TDDAALLEQAGHPVAIVEGSEDNIKLTVAEDLMRLEGVIDRN---
ISPDF_GRABC LALHRDHPGGA----TDDAALLDQAGHSVALVPGAEDNIKVTYPADLARVERSMSIS---
ISPDF_PARDP LAAHRAHPEGA----ADDVELAIRAGLPVTVTPGDEDNLKLTWPGDFARAERILGD----
ISPDF_RHOCB LAAHRAHPGGA----ADDVEVARHAGLSVAIVPGHEDNLKITYAPDFARAEAILRERK--
ISPDF_RUEPO VAAHAAHPGGA----ADDVEVARAAELTVAIVPGDPDNLKITRAEDFARAERILRQDM--
ISPDF_RUEST LAAHMRHDGTA----ADDVEVARQAGLAVRITPGDVNNIKITRPEDFSRAEHILRSTM--
ISPDF_JANSC RAAHAAHDGTA----ADDVEVARLAGIDVAIVPGDEANLKITGPEDFARAEALLTGG---
ISPDF_ERYLH LAAHRAWTGATD--AGDDAQVLMAHGGDIALVEGDEALKKLTFAEDFM--ADLLPV----
ISPDF_NOVAD LAAHRAWQGEAL--AGDDAQVAMRAAHEIALVEGDEALRKVTFASDLE--EQSMSVI---
ISPDF_SPHAL RRAHAEASGAA---ATDDAQLVRSLGVSVATVEGDARLHKLTYAADMAILAGLLGTKD--
ISPDF_ZYMMO IAAHQAWTGSDE--PTDDAQVVRAFGKKIALVTGDRLLEKLTYPADFSVAEAQMTEK---
ISPDF_CAUVC IAAYAAWTHGE---PTDDAQVVEAAGGRIALTAGDPLLTKLTYPEDFAMAEHLAGVA---
ISPDF_HYPNA RAALSAAGPDL----VDDLTAIEAAGGRVEIVSGSARLTKITYPEDFDMLARLLSPT---
ISPDF_MAGSA VAAHHAVIGNE---LTDDAAVAEKAGLAVELVNGAEDNVKITTGADLERARCLFDGP---
ISPDF_RHORT LAAHRAQAGTM---LTDDAAVLEAAGGAVALVDGAEDNAKITTFADLERAERLFRGE---
ISPDF_MARMM LKAYARLGDTA---LPDDAAVIRAAGGEVALVPGEAENFKLTTRADFERAERQIMSE---
ISPDF_ANADE EQAYAAAGPSASA-ATDECALVEAAGAPVTLVPGEPGNFKITGPDDVRRARALLEAP---
ISPDF_TROW8 EAAHERSVASNEQ-FADDSVMVAQIEKDITLINGHEASFKVTNPCDLQRAEFAASSLLSK
ISPDF_TROWT EAAHERSVASNEQ-FADDSVMVAQIEKDITLINGHEASFKVTNPCDLQRAEFAASSLLSK
: * *:: :.
ISPDF_DESPS -------------KKEPMQKIRIGHGFDAHQLVEK-------RRLILGGVEIPYHLGLAG
ISPDF_ALBFT DSAPQQSASEF--KRASDMNFRIGEGWDIHALVAG-------RKLLLGGVEIPYHLGLLG
ISPDF_CAMJE -----------------SFEIFTGNGFDVHEFGE-------NRPLLLAGVQIHPTMGLKA
ISPDF_CAMJR -----------------SFEIFTGNGFDVHEFGE-------NRPLLLAGVQIHPTMGLKA
ISPDF_CAMJJ -----------------SFEIFTGNGFDVHEFGE-------NRPLLLAGVQIHPTMGLKA
ISPDF_CAMFF -----------------SNDIFCGNGFDVHAFKE-------GDFITLCGVKIPYSKAFIA
ISPDF_SULDN -----------------SSDTLSGVGFDVHAFDD-------KGEMFLGGIKIDSEYGFLA
ISPDF_HELHP -----------------SKRVFIGNGIDVHQFEK-------NKQMWLGGVEIESPFGFKA
ISPDF_WOLSU -----------------FGGCYGGSGFDVHAFME-------GEGLRLAGVNIPAPVTFKA
ISPDF_HELPY -----------------AKDTFIGMGFDTHAFIK-------DKPMVLGGVVLDCEFGLKA
ISPDF_HELPH -----------------AKDTFIGMGFDTHAFIK-------DKPMVLGGVVLDCEFGLKA
ISPDF_HELPJ -----------------AKDTFIGMGFDTHAFIK-------DKPMVLGGVVLDCEFGLKA
ISPDF_HELAH -----------------AKDTFIGMGFDTHAFIK-------DKPMVLGGVVLDCEFGLKA
ISPDF_PELUB -----------------NNLIKFGIGFDVHRLVP-------NKKLYLGGVKIPSPIGTLG
ISPDF_DESVH -----------------VTVPCVGWGYDVHRYG-------EGRPMKLGGVLIPEGPEVVA
ISPDF_DESVV -----------------VTVPCVGWGYDVHRYG-------EGRPMKLGGVLIPEGPEVVA
ISPDF_OLEA2 -----------------MQVPCVGWGYDVHRFGS------DGRPMKLGGVPIAGGPGVIA
ISPDF_LAWIP -----------------TTVPIVGYGYDVHKYVTEDQINQPIRSMRLGGISIPNAPNVVA
ISPDF_WOLPM -----------------EPKFRVGAGYDIHKFIKVQ--NGAESFIKICGVKIEHNMAIEA
ISPDF_RHIEC ----------------MLPDVRTGNGYDVHQLEPG-------DGVTLCGVFIPHDQRLKG
ISPDF_RHIJ3 ----------------LLPDVRTGNGYDVHQLVAG-------DGVTLCGVFIPHDQKLKG
ISPDF_RHIME ----------------AIPDVRTGNGYDVHQLVDG-------DGVTLCGVFIPHGRKLSG
ISPDF_AGRFC ----------------ALPDVRTGNGYDVHQLEAG-------DGVTLCGIFIEHDQRLKG
ISPDF_BARHE ---------------QMFPDIRTGNGYDVHSFEEG-------NSLILCGIKIPFHKKLNG
ISPDF_BARQU ---------------QMFPDIRTGNGYDVHSFEEG-------TSLILCGIKIPFHKKLKG
ISPDF_BARBK ---------------QIFPDIRTGNGYDVHSFEDG-------HYITLCGIKIPFEKKLNG
ISPDF_BRUAB ---------------AVFPDIRTGNGYDVHSFEPG-------DHVTLCGVKIPHEAKLNG
ISPDF_BRUA2 ---------------AVFPDIRTGNGYDVHSFEPG-------DHVTLCGVKIPHEAKLNG
ISPDF_BRUME ---------------AVFPDIRTGNGYDVHSFEPG-------DHVTLCGVKIPHEAKLNG
ISPDF_BRUSU ---------------AVFPDIRTGNGYDVHSFEPG-------DHVTLCGVKIPHEAKLNG
ISPDF_RHILO ---------------THFPDIRTGNGYDVHAFEPG-------DHVTLCGVAIPHDKKLSG
ISPDF_CHESB ---------------TELPDIRVGNGYDVHGFGPG-------GHVTLCGVQIPHGKTLMG
ISPDF_BRASB -----------------LGDIRTGTGYDVHAFGEG-------DHVWLCGLRVPHSKGFLA
ISPDF_BRASO -----------------LGDIRTGTGYDVHAFGEG-------DHVWLCGLRVPHTKGFLA
ISPDF_BRADU -----------------LGDIRTGTGYDVHAFGEG-------DHVMICGVRVPHSKGFLA
ISPDF_NITHX -----------------LGDIRTGTGYDVHAFGDG-------DHVMLCGVKVPHNRGFLA
ISPDF_NITWN -----------------LGDIRTGTGYDVHAFGEG-------DHLMLCGVKVPHNCGFLA
ISPDF_RHOPS -----------------LGDIRTGTGYDVHAFGDG-------DHVWLCGLKVPHNRGFLA
ISPDF_RHOP2 -----------------LGDIRTGTGYDVHAFGDG-------DHVWLCGLKVPHNRGFLA
ISPDF_RHOPA -----------------LGDIRTGTGYDVHAFGEG-------DHVWLCGLKVPHTRGFLA
ISPDF_RHOP5 -----------------LGDIRTGTGYDVHAFGDG-------DHVWLCGLKVPHNRGFLA
ISPDF_RHOPB -----------------LGDIRTGTGYDVHAFGDG-------DHVWLCGLKVPHNRGFLA
ISPDF_GLUOX ------------------LLPRVGLGYDVHAFEEG-------RKLILCGIEVPHTKGLAG
ISPDF_GRABC ------------------MIPRIGTGYDVHAFETG-------RKLILCGIEVPHHQGLAG
ISPDF_PARDP -----------------AMDIRLGNGFDVHAFTTG-------DHVWLCGVKIPHDKALLG
ISPDF_RHOCB ---------------GLTMDVRLGNGYDVHAFCEG-------DHVVLCGVKVPHVKALLG
ISPDF_RUEPO ---------------D----VRLGNGYDVHRFGPG-------DHVILCGIKVPHDRGLQG
ISPDF_RUEST ---------------DNIPDIRLGNGYDVHRFGPG-------DHVMLCGVQVPHERGLQG
ISPDF_JANSC -----------------DMDIRVGNGFDVHRFGPG-------DQVWLCGISVPHTRGLQG
ISPDF_ERYLH ---------------------RVGTGFDVHKLEAG-------EELWLGGIRLEHDKGLAG
ISPDF_NOVAD --------------------PRTGMGFDVHRLVEG-------EELWLCGVNIPHGKGLSG
ISPDF_SPHAL ---------------M--MRTAVGMGYDVHRLVEG-------KPLWIGGIEIAHSHGLEG
ISPDF_ZYMMO ------------------MISVCGSGFDVHCFEAG-------DHIMLGGIKIPHDHGLAG
ISPDF_CAUVC ------------------RVTRVGQGFDAHRWGPG-------EEVWLCGVAIKHDETLVG
ISPDF_HYPNA ------------------GAPRIGKGYDVHEFEAG-------DHVTLCGVAIPHIAKLKG
ISPDF_MAGSA ------------------GEVRSASGYDVHRFDPAK------DACWLCGVPVPHEAGLLG
ISPDF_RHORT ------------------GEQRIGSGFDVHRLGPG-------DFVTLNGIRIPHSHGLVG
ISPDF_MARMM ------------------TITVTGQGYDVHRLEPA-------DVMWLCGVEIRAGLGLIG
ISPDF_ANADE --------------------VATGVGYDTHRFAPG-------RRLVLGGVEFEGD-GLLG
ISPDF_TROW8 SNVSPVNISQPPISALSMPLPLIGVGIDFHKFILD------ESPLFLACLEWKNYRRLQG
ISPDF_TROWT SNVSPVNISQPPISALSMPLPLIGVGIDFHKFILD------ESPLFLACLEWKNYRRLQG
. * * * : : .
ISPDF_DESPS HSDADVLVHALCDALLGAIGAGDIGRHFPDSSDAFKDIYSIRLLESVMQKVGELNYKIGN
ISPDF_ALBFT HSDADVLLHAITDALLGAAALGDIGTHFPDTDARFKGADSLVLLTEAARRVRAKGFEIGN
ISPDF_CAMJE HSDGDVLAHSLTDAILGAAGLGDIGELYPDTDMKFKNANSMELLKQAYDKVREIGFELIN
ISPDF_CAMJR HSDGDVLAHSLTDAILGAAGLGDIGELYPDTDMKFKNANSMELLKQAYDKVREIGFELIN
ISPDF_CAMJJ HSDGDVLAHSLTDAILGAAGLGDIGELYPDTDMKFKNANSMELLKQAYDKVREVGFELIN
ISPDF_CAMFF HSDGDVALHALCDALLGAASAPDIGELYPDNDSKFKDIDSKILLQNSVNLIRSIGFDIIN
ISPDF_SULDN HSDGDVAIHALIDALLGAAGMGDIGMMFPDNDVKYKGADSKELLGTLVTKLRHFGFVIVN
ISPDF_HELHP HSDGDVVLHALSDAILGAIGGGDIGEWFPDTDETYKNADSKMMLSEIYTFAQSVGYELYN
ISPDF_WOLSU HSDGDVAIHALIDALLGAAGAGDIGEWFPDSDLAYKGVDSTLLLQEVIKFIRGIGFELIN
ISPDF_HELPY HSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFE
ISPDF_HELPH HSDGDALLHAVIDAVLGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFE
ISPDF_HELPJ HSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELLE
ISPDF_HELAH HSDGDALLHAMIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFE
ISPDF_PELUB HSDGDPVLHAVTDAILGACSMGDIGEKFSDKNKKFKNIRSTILLSEIIKQTLKKGYLINN
ISPDF_DESVH HSDGDVLLHALADALLGCIGAGDIGLHFPDSDAAFDNANSAMLLDRVLHMTHEARLRLTH
ISPDF_DESVV HSDGDVLLHALADALLGCIGAGDIGLHFPDSDAAFDNANSAMLLDRVLHMTHEARLRLTH
ISPDF_OLEA2 HSDGDVLLHALTDAVLGCMGLGDIGMLFPDTDAAYDNADSAVMLNEVLEKARNAGLLITH
ISPDF_LAWIP HSDGDVLLHALMDALLGCIGGGDIGLHFPDSDKRYDGINSAILLDHVLTKVLESSIKIVH
ISPDF_WOLPM HSDGDVAIHAIVDAILGALGCGDIGEHFPPSSSEWKDCNSSHFLDFAAKKAKEKGYSVSN
ISPDF_RHIEC HSDADVALHALTDALLATCGAGDIGDHFPPSDPQWKGAASKIFIEHAARIVRERGGTIMN
ISPDF_RHIJ3 HSDADVALHALTDALLATCGAGDIGDHFPPSDPQWKGAASRIFIEHAARIVRERGGTIMN
ISPDF_RHIME HSDADVALHALTDALLATCGAGDIGDHFPPSDPQWKGAPSRIFLEHAARIVRERGGTVTN
ISPDF_AGRFC HSDADVALHALTDALLATCGAGDIGDHFPPSDPQWKGAASRIFLEHAAKVVRDNGGTIMN
ISPDF_BARHE HSDADVALHALTDALLATRGAGDIGTHFPPSDPQWQNVSSEIFLRHALDIVKQAGGRIAN
ISPDF_BARQU HSDADVAFHALTDALLATQGAGDIGTHFLPSDPQWKNAPSEIFLRHALEIIKQAGGRIAN
ISPDF_BARBK HSDADVALHALTDALLATQGAGDIGTHFPPSDPQWKNASSEIFLHHAIEIIKKAEGRIAN
ISPDF_BRUAB HSDADVALHALTDALLATRGAGDIGTHFPPSDPQWKGAASRIFIEHAAKIVREAGGRIAN
ISPDF_BRUA2 HSDADVALHALTDALLATRGAGDIGTHFPPSDPQWKGAASRIFIEHAAKIVREAGGRIAN
ISPDF_BRUME HSDADVALHALTDALLATRGAGDIGTHFPPSDPQWKGAASRIFIEHAAKIVREAGGRIAN
ISPDF_BRUSU HSDADVALHALTDALLATRGAGDIGTHFPPSDSQWKGAASRIFIEHAAKIVREAGGRIAN
ISPDF_RHILO HSDADVGLHALTDALLATCGAGDIGTHFPPSDPQWKGAASRIFVEHAAKVVRQRGGRIAN
ISPDF_CHESB HSDADVGLHALTDALLATCGAGDIGTHFPPSDPQWKGAKSRIFVEHAVNLLRARGGRIAN
ISPDF_BRASB HSDGDVGLHALVDAILGALADGDIGSHFPPSDMKWKGASSDQFLKYAIERVTARGGRVAN
ISPDF_BRASO HSDGDVGLHALVDAILGALADGDIGSHFPPSDMKWKGASSDQFLKYAIERVAARGGRVAN
ISPDF_BRADU HSDGDVGLHALVDAILGALADGDIGSHFPPSDAKWKGASSDQFLKYAIERVAQRGGRVAN
ISPDF_NITHX HSDGDVGLHALVDAILGALADGDIGSHFPPSDPQWKGAASDKFLKYAVDRVAARGGRIAN
ISPDF_NITWN HSDGDVGLHALVDAILGALADGDIGSHFPPSDPQWKGAASDKFLKYAVDRVTARGGRVAN
ISPDF_RHOPS HSDGDVGLHALVDAILGALADGDIGSHFPPTDPQWKGAASDKFLKYAVERVAARGGRIAN
ISPDF_RHOP2 HSDGDVGLHALVDAILGALADGDIGSHFPPTDPQWKGAASDKFLKYAVDRVAARGGRIAN
ISPDF_RHOPA HSDGDVGLHALVDAILGALADGDIGSHFPPTDPQWKGAASDKFLKYAIDRVTARGGRVAN
ISPDF_RHOP5 HSDGDVGLHALVDAILGALADGDIGSHFPPTDPQWKGAASDKFLKYAIDRVHARGGRIAN
ISPDF_RHOPB HSDGDVGLHALVDAILGALADGDIGSHFPPTDPQWKGAASDKFLKYAVDRVTARGGRIAN
ISPDF_GLUOX HSDADVGIHTLCDAIYGALAEGDIGRHFPPSDNKWKDMDSARFLVHAGERIRERGGFLVN
ISPDF_GRABC HSDADVGIHALCDAIYGALAEGDIGRHFPPTEASWKDADSARFLRHAAERIAARGGFLAN
ISPDF_PARDP HSDADVGMHALTDAIYGALAQGDIGRHFPPSDPQWKGAESHIFLRHAAMLARQMGYEISN
ISPDF_RHOCB HSDADVGMHALTDAIYGALAEGDIGRHFPPSDPQWKGAASWIFLDHAAKLAKSRGFRIGN
ISPDF_RUEPO HSDADVGMHAVTDALYGALVEGDIGRHFPPSDPQWKGAASEIFLRHAVDLVRARGFAVSN
ISPDF_RUEST HSDADVGMHAVTDALYGAMAEGDIGRHFPPSDPQWKGAASDIFLRHAVELARSKGFTINN
ISPDF_JANSC HSDADVGLHTLTDAIYGALAEGDIGTHFPPSDPQWKDAESHIFLTHAVELAANRGFSITN
ISPDF_ERYLH HSDADVALHAIVDALLGAIGKGDIGDHFPPSDPQWKGAASSAFIEHAAKLVDEAGYRVGN
ISPDF_NOVAD HSDADVAIHALVDALLGAIAAGDIGDHFPPSDPQWKGASSDRFLAHAGTLVTEAGYRIAN
ISPDF_SPHAL HSDADVGLHALTDAILGALGDGDIGDHFPPSDPQWRGAASHHFLSFAGERVAANGGRIGH
ISPDF_ZYMMO HSDADVALHALTDALLGAIADGDIGTHFPPSDPQWKGANSTQFLEYAVALAKKAGAIIDH
ISPDF_CAUVC HSDADAGLHALTDAILGAIGEGDIGDHFPPTDPKWKGAASDQFLKHAVDLVTAKGGALVN
ISPDF_HYPNA HSDADAAWHALTDAILGAVALGDIGDHFPPSDPQWKGADSGLFLKEAQRLAEAKGYVIAN
ISPDF_MAGSA HSDADVGLHALTDAVLGAISAGDIGHHFPPTDARWKGAASDQFLAHAGSLVTAKGGRIVN
ISPDF_RHORT HSDADAPMHALTDALLGCLNAGDIGRHFPPSDMRWKGADSAIFLRHAAALITALGGRILN
ISPDF_MARMM HSDADAGLHALTDAVLGAAGAGDIGQHFPPSDPQWKGAASDAFLLHAIKLLKQVGGELVH
ISPDF_ANADE HSDADVCAHAIGDAILGAAGLGDLGRHFPDTDPRWKGVSSLALLREIAAKAAERGWRVGN
ISPDF_TROW8 HSDGDVVAHACTTALLSAANMGDIGSVFGVDLAATKDASGAYFLESTNRLLATNGFCVLN
ISPDF_TROWT HSDGDVVAHACTTALLSAANMGDIGSVFGVDLAATKDASGAYFLESTNRLLATNGFCVLN
***.* *: *: . *:* : . . :: : .
ISPDF_DESPS ADISVICQAPKLAPYLKQMQEIIATSCACQISDINIKATTTEKMGYTGRGEGISCHAVVL
ISPDF_ALBFT VDSTVIAQAPKLMPYMAAMRAQIALALALEVDQVNVKAKTAEKMGPVGLGQAMEARATVL
ISPDF_CAMJE IDICVMAQSPKLKDFKQAMQSNIAHTLDLDEFRINVKATTTEKLGFIGRKEGMAVLSSVN
ISPDF_CAMJR IDICVMAQSPKLKDFKQAMQSNIAHTLDLDEFRINVKATTTEKLGFIGRKEGMAVLSSVN
ISPDF_CAMJJ IDICVMAQSPKLKDFKQAMQSNIAHTLDLDEFRINVKATTTEKLGFIGRKEGMAVLSSVN
ISPDF_CAMFF ADITIIAQSPKISPYKDAMAKIVADILGIPLHKVNIKATTTEHLGFIGRNEGIAANAIVN
ISPDF_SULDN VDITIAAEKPRIGNYKMAMRKKISSILGIDAQRVNIKATTTEKLGFIGRGEGVGVIANAN
ISPDF_HELHP ADISIIAQTPKIAPYKSAMRECIARILRVPNAHINIKATTTEGLGFVGREEGVCVEACVS
ISPDF_WOLSU ADLTIMAQAPKLSPYKEAMERRLGEVMEVSRQRISVKATTTESLGFVGRKEGVAVSAQVV
ISPDF_HELPY MGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVS
ISPDF_HELPH MGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVS
ISPDF_HELPJ MGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVS
ISPDF_HELAH MGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGQQEGLLVQAHAS
ISPDF_PELUB LDINIITQKPKIQKYKKQILNCIAKICNISPTQINIKGKTTEKLGVIGKEKAIACEVIAS
ISPDF_DESVH VDLTIVAQVPKLSPWRDKIRANVARLLDLPVTSVNFKATTEEGLGFTGEKRGIKAIAAVT
ISPDF_DESVV VDLTIVAQVPKLSPWRDKIRANVARLLDLPVTSVNFKATTEEGLGFTGEKRGIKAIAAVT
ISPDF_OLEA2 VDLTIITQIPRITPWRDQIHKNICRITRLDASSVNLKATTEEKLGFTGEKKGIKAVAAVT
ISPDF_LAWIP MDATIVAQLPKISQYREAIRSNLSRLLDLDLANVNIKATTEEGLGFTGECKGIKAIVIVT
ISPDF_WOLPM LDITIVCEEPKISPYKVEMKKFISKALEIDDEFVNIKATTAEKLGYIGRNEGIAVHASVL
ISPDF_RHIEC ADVSLIAEAPKVGPHREAMRARLSEYLGIDIERCSVKATTNEKIGFVGRREGIAAIATAT
ISPDF_RHIJ3 ADVSLIAEAPKVGPHRDAMRAKLSDYLGIDIERCSVKATTNETIGFVGRREGIAAIATAT
ISPDF_RHIME ADISLIAEAPKVGPHRQQMRENLAAILGISLDRCSIKATTNEKLGFVGRNEGIAAIATAT
ISPDF_AGRFC ADVSLIAEAPRIGPHRQAMREALSDMLGIALERCSVKATTNETIGFVGRREGIAAIATAT
ISPDF_BARHE VDITLIAEEPKIGPYRHAMVGNLMNMLTILPDRISIKATTNEKLGFIGRGEGIAAFATAN
ISPDF_BARQU VDITLIAETPKIGPYRHTMTENLMNILSLSLDRISIKATTNEKLGFIGREEGIAALATAT
ISPDF_BARBK VDITLIAEKPKIGPYRHIMTENLMKILKISTDRISIKATTNEKLGFIGREEGIAALATAT
ISPDF_BRUAB VDVTLISEAPKIGPHRAAMTQALCDMLGIAADRVSIKATTNEKLGFVGRREGIAAIATAT
ISPDF_BRUA2 VDVTLISEAPKIGPHRAAMTQALCDMLGIAADRVSIKATTNEKLGFVGRREGIAAIATAT
ISPDF_BRUME VDVTLISEAPKIGPHRAAMTQALCDMLGIAADRVSIKATTNEKLGFVGRREGIAAIATAT
ISPDF_BRUSU VDVTLISEAPKIGPHRAAMTQALCDMLGIAADRVSIKATTNEKLGFVGRREGIAAIATAT
ISPDF_RHILO ADITLICEAPRVGPHREAMTAALSRMLGISADRISIKATTNEKLGFVGREEGIAAIATAS
ISPDF_CHESB ADVTLICEAPRIGPYREAMLAELSDMLQISPERVSVKATTNEGLGFIGRAEGIAAIATAT
ISPDF_BRASB LEVTMICERPKIGPLRDQMRARIAEISGVDISRIAVKATTSERLGFTGREEGIAATASAT
ISPDF_BRASO LEVTMICERPKIGPLRDQMRARIAEISGVDISRIAVKATTSERLGFTGREEGIAATASAT
ISPDF_BRADU LEVTMICERPKIGPLRDTMRARIAEISGVDISRVAVKATTSERLGFTGREEGIAATASAT
ISPDF_NITHX LEVTMICERPKIGPLRDTMRARIAEITGVAISRIAVKATTSERLGFTGREEGIATTASAT
ISPDF_NITWN LEVTMICQQPKIGPLRDQMRARIADITGVAISRIAVKATTSERLGFTGREEGIAATASAT
ISPDF_RHOPS LEVTMICERPKIGPLREAMRARIAEITGLPVSRIAVKATTSERLGFTGREEGIAATASAT
ISPDF_RHOP2 LEVTMICERPKIGPLRDPMRQRIAEITGVPVSRVAVKATTSERLGFTGREEGIAATASAT
ISPDF_RHOPA LEVTMICERPKIGPLRDAMRQRIAEITGVPVSRVAVKATTSEKLGFTGREEGIAATASAT
ISPDF_RHOP5 LEVTMICERPKIGPLREAMRERIAEITGLPVSRIAVKATTSERLGFTGREEGIAATACAT
ISPDF_RHOPB LEVTMICERPKIGPLREPMRQRIAEITGLPVARIAVKATTSERLGFTGREEGIAATASAT
ISPDF_GLUOX ADVTLICERPKIGPHAEAMRNRLADLLKVSVSRISVKATTSERLGFTGREEGIAATATVS
ISPDF_GRABC ADLTLICEKPKITPHAPAMIARLAELLGVSIDKISVKATTSEKLGFTGREEGIAAQAAVI
ISPDF_PARDP ADVTLICERPKVGPHAGAMALRLSEIIGVEPDRVSVKATTSERLGFTGREEGIASIATAT
ISPDF_RHOCB ADVTLICERPKVGPHAVAMAAELARIMEIEPSRVSVKATTSERLGFTGREEGIASIATVT
ISPDF_RUEPO IDCTLVCEYPKIGPHALEMQAEMARIMGLEASRVSVKATTSERLGFTGRSEGIAALATAC
ISPDF_RUEST VDCTLVCEYPKVGPHAEAMRARMAEIMGMDMGRLSIKATTSERLGFTGRKEGIAALATAT
ISPDF_JANSC ADLTLICEQPKIGPVASAMRARVADLLRIDVARVSVKATTSERLGFTGREEGIAALATIT
ISPDF_ERYLH IDLTIICEAPRIGPHRDAMGQRIAELLATSPDAISVKATTTEKLGFTGRGEGIAAQAAAT
ISPDF_NOVAD VDVTIICEAPKIGPHKAAMRETLARILGIDSALVSVKATTTERLGLTGRGEGIAAQAVAT
ISPDF_SPHAL LDLTIIAEAPRIGPHRVAIRDRIAEILAIPAGRVSVKATTTERLGFTGRREGIAAQAVAT
ISPDF_ZYMMO ADVTVICEAPKVGPYRPAMRKHIAQILGLPEQRVSIKATTTEKLGFTGRKEGIAAQAVTS
ISPDF_CAUVC VDVTLICERPKIKPHRQAMRERLAEILSIPVDRVSVKATTTEKMGFTGRGEGLAASAVVA
ISPDF_HYPNA CDITVICEAPKVKPHREAMRARTAELLGLPLDAVSVKATTTEGLGFTGRREGIAAEAVAL
ISPDF_MAGSA VDVTIICERPKVGPHRAAMAARVAEILGISQDRVSVKATTTEGLGFTGRKEGIAAQAMAS
ISPDF_RHORT VDITILCEQPKIGPHRARMSARLAEILEISATRVAVKATTTEELGFTGRGEGIAAQATAL
ISPDF_MARMM ADITLIAERPKIGPHRDAMRARVAELTGLPEKRVNIAATTTEKLGFTGRGEGLAAQAIVT
ISPDF_ANADE CDVTLAAKRPKIAPRAEEMRARLAGALGISPAQVNVKATTGEGMGFVGREEGVAAHAIAL
ISPDF_TROW8 IAVQVISNTPRLADRRVEAEHAISDCLSG--ARISLSSVTTDGMGFLGRGEGIGAIAVAQ
ISPDF_TROWT IAVQVISNTPRLADRRVEAEHAISDCLSG--ARISLSSVTTDGMGFLGRGEGIGAIAVAQ
: : *:: . . * : :* * ..:
ISPDF_DESPS LQQ-----------------
ISPDF_ALBFT LRKFI---------------
ISPDF_CAMJE LKYFDWTRL-----------
ISPDF_CAMJR LKYFDWTRL-----------
ISPDF_CAMJJ LKYFDWTRL-----------
ISPDF_CAMFF LKYFNWRNVL----------
ISPDF_SULDN LKYFDWTKI-----------
ISPDF_HELHP MGFINWHTYIKDLH------
ISPDF_WOLSU LKLLDWTKHACFNR------
ISPDF_HELPY MRYKQKL-------------
ISPDF_HELPH MRYKQKL-------------
ISPDF_HELPJ MRYKQKL-------------
ISPDF_HELAH MRYKQKL-------------
ISPDF_PELUB VIKND---------------
ISPDF_DESVH GLRPMP--------------
ISPDF_DESVV GLRPMP--------------
ISPDF_OLEA2 ALRRVSS-------------
ISPDF_LAWIP AIRIS---------------
ISPDF_WOLPM LHTNFYWK------------
ISPDF_RHIEC VVYRW-----RKR-------
ISPDF_RHIJ3 VVYRG-----RK--------
ISPDF_RHIME VVYAS-----RSKPDVDDRY
ISPDF_AGRFC VVYQG-----RPL-------
ISPDF_BARHE VLYPG-----EIPK------
ISPDF_BARQU VLYPG-----EIPK------
ISPDF_BARBK VIYPG-----EIPK------
ISPDF_BRUAB VIYPG-----EVPE------
ISPDF_BRUA2 VIYPG-----EVPE------
ISPDF_BRUME VIYPG-----EVPE------
ISPDF_BRUSU VIYPG-----EVPE------
ISPDF_RHILO VVFPG-----EVPE------
ISPDF_CHESB VAYPG-----SLGN------
ISPDF_BRASB IRLPW-----SA--------
ISPDF_BRASO IRLPW-----GA--------
ISPDF_BRADU IRLPF-----NEKTWSV---
ISPDF_NITHX VRLPWNDSDQEDKGWST---
ISPDF_NITWN IRLPWND-----KGRDT---
ISPDF_RHOPS IRLPW-----GAEGLAG---
ISPDF_RHOP2 IRLPWSP--WGAEGQAS---
ISPDF_RHOPA IRLPW-----GADGLAG---
ISPDF_RHOP5 IRLPW-----GPNGLSG---
ISPDF_RHOPB LRLPW-----GTNGLAD---
ISPDF_GLUOX IMVPDNGEA-----------
ISPDF_GRABC IMIPA---------------
ISPDF_PARDP LVKG----------------
ISPDF_RHOCB LIGA----------------
ISPDF_RUEPO LVKP----------------
ISPDF_RUEST LVRA----------------
ISPDF_JANSC LVAR----------------
ISPDF_ERYLH VVRKDTPA------------
ISPDF_NOVAD VVSG----------------
ISPDF_SPHAL IQLPET--------------
ISPDF_ZYMMO IRLPDILC------------
ISPDF_CAUVC VETPA---------------
ISPDF_HYPNA LMPKG---------------
ISPDF_MAGSA VWLPR---------------
ISPDF_RHORT ITLPF---------------
ISPDF_MARMM ARLTT---------------
ISPDF_ANADE LVRAAG--------------
ISPDF_TROW8 IYHR----------------
ISPDF_TROWT IYHR----------------