CLUSTAL format seed alignment for MF_01931

_____________________________________________________________________________

Features found in the protein:_____________________________________________________________________________

PUR1_ECOLI        ------------------------------------------------------------
PUR1_HAEIN        ------------------------------------------------------------
PUR1_PSEAE        ------------------------------------------------------------
M5CIZ2_STEMA      ------------------------------------------------------------
PUR1_YEAST        ------------------------------------------------------------
PUR1_LACKL        ------------------------------------------------------------
PUR1_SCHPO        ------------------------------------------------------------
N1PZ93_DOTSN      ------------------------------------------------------------
A2BTW0_PROM5      ------------------------------------------------------------
H6LAZ2_SAPGL      ------------------------------------------------------------
W5X8L7_BDEBC      ------------------------------------------------------------
PUR1_METJA        ------------------------------------------------------------
PUR1_METTH        ------------------------------------------------------------
PUR1_ARCFU        ------------------------------------------------------------
D1CBD4_THET1      -----------------------------------------------------MLCKPVD
PUR1_RAT          ------------------------------------------------------------
PUR1_HUMAN        ------------------------------------------------------------
PUR1_CHICK        ------------------------------------------------------------
PUR1_DROME        ---------------------------MSAPQQQQQSQQKQQQHVRVVEQQQVEPAEAVT
PUR1_DICDI        ------------------------------------------------------MENNNN
PUR1_STAAC        ------------------------------------------------------------
PUR1_STAES        ------------------------------------------------------------
PUR1_BACSU        ------------------------------------------------------------
PUR1_RHIEC        ----------------------------MNQSHSFPTDDPL-------------------
Q3YT14_EHRCJ      ----------------------------------------M-------------------
PUR1_SOYBN        MAAASNLSTLSSSSLSKPSSSFPFRNTPTNNNASFLHNKSLPNQNSLSHKLSSPLPLACN
PUR1_SYNY3        ----------------------------MFPPSSDLTELNDG--QPLSGHH---------
PUR1_MYCTU        ----------------------------MAVDSDYVTDRAAGSRQTVTGQQ---------
A7GHD3_CLOBL      ------------------------------------------------------------
T4VR46_PARBF      ------------------------------------------------------------
A5TUR7_FUSNP      ------------------------------------------------------------
A5IMV9_THEP1      ------------------------------------------------------------
B9K970_THENN      ------------------------------------------------------------
A6LK07_THEM4      ------------------------------------------------------------
PUR1_PYRAB        ------------------------------------------------------------
F4B9T2_ACIHW      ------------------------------------------------------------
A4YI69_METS5      ------------------------------------------------------------
F0NPQ9_SULIH      ------------------------------------------------------------
Q4J8F7_SULAC      ------------------------------------------------------------
I0A0P7_FERFK      ------------------------------------------------------------
E0SQP0_IGNAA      ------------------------------------------------------------
F0QVW3_VULM7      ------------------------------------------------------------
A8MCK1_CALMQ      ------------------------------------------------------------
A8AAY0_IGNH4      ------------------------------------------------------------
A9A5G6_NITMS      ------------------------------------------------------------
E8R3Q7_ISOPI      ------------------------------------------------------------
L0DBH0_SINAD      ------------------------------------------------------------
Q7UGS5_RHOBA      ------------------------------------------------------------
                                                                              

PUR1_ECOLI        -------------------MCGIVGIAGVMP---------------VNQSIYDALTVLQH
PUR1_HAEIN        -------------------MCGIVGIVSQSP---------------VNESIYAALTLLQH
PUR1_PSEAE        -------------------MCGIVGIVGKSN---------------VNQALYDALTVLQH
M5CIZ2_STEMA      ------------------------------------------------------------
PUR1_YEAST        -------------------MCGILGIVLANQT------------TPVAPELCDGCIFLQH
PUR1_LACKL        -------------------MCGILGIALADQS------------SVVAPELFDGSLFLQH
PUR1_SCHPO        -------------------MCGILALMLADPH------------QQACPEIYEGLYSLQH
N1PZ93_DOTSN      -------------------MCGILAVILASTS------------ADAAPELHQALYYLQH
A2BTW0_PROM5      -------------------MCGIVGIVSSDD---------------VNQQIYDSLLLLQH
H6LAZ2_SAPGL      -------------------MCGIVGFYGKPN---------------IVYDLMLGLSALQH
W5X8L7_BDEBC      -------------------MCGVVGLIGEEN---------------AGEKLYPALFALQH
PUR1_METJA        -------------------MCGIFGIYS---YE---------R-LNVAKKIYYGLFALQH
PUR1_METTH        --MLGE--------SEVRDKCGIVGIYS---QD---------KKTGVASQIYYALYALQH
PUR1_ARCFU        -------------------MCGVVGIYH---PD---------G-ELAPRLAYYSLFSLQH
D1CBD4_THET1      YNLLQM--------DALHEECGVIGIWQ---PR---------EVFDTANYLVLGLTELQH
PUR1_RAT          --MELE-------ESGIREECGVFGCIASGDWP---------TQLDVPHVITLGLVGLQH
PUR1_HUMAN        --MELE-------ELGIREECGVFGCIASGEWP---------TQLDVPHVITLGLVGLQH
PUR1_CHICK        --MELE-------ELGIREECGVFGCIAAGVWP---------TELDVPHVITLGLVGLQH
PUR1_DROME        SSMESESISASKELTGLTHECGVFGAIACGDWP---------TQMDIAHVICLGLVALQH
PUR1_DICDI        NFIEEE-----EELSEPKEKCGVFAIYA--------------PELDVSRIAFFGLVALQH
PUR1_STAAC        ----------MFNYSGLNEECGVFGIWNHP--------------E-AAQLTYMGLHSLQH
PUR1_STAES        ----------MSNYSGLNEECGVFGIWNHP--------------E-AAQLTYMGLHSLQH
PUR1_BACSU        ---------MLAEIKGLNEECGVFGIWGHE--------------E-APQITYYGLHSLQH
PUR1_RHIEC        ------------DGDTLHEECGVFGILGHP--------------D-AAALTALGLHALQH
Q3YT14_EHRCJ      ------------QFKEVYEECGIFAIQNNR--------------R-AAVNCILGLHALQH
PUR1_SOYBN        PKNQNTCVFFDDEDQKPREECGVVGIYGDP--------------E-ASRLCSLALHALQH
PUR1_SYNY3        ---------ADK----PEEACGVFGIYAPE--------------EAVAKLTYFGLYALQH
PUR1_MYCTU        ---------PEQDLNSPREECGVFGVWAPG--------------EDVAKLTYYGLYALQH
A7GHD3_CLOBL      -------MLFDKEQDKFREECGVFGIFKDY-------------TSELGEIFYPGLVSLQH
T4VR46_PARBF      -------MQIDN-MDKYKEECGVVGLFSTK-------------KINLHSSLYSSLITLQH
A5TUR7_FUSNP      --------------------MGILALHSKKV------------RKDLVGIAYYGMYALQH
A5IMV9_THEP1      -------------------MCGIAGVWNV---------------KDAFSVLHDVLLGLQH
B9K970_THENN      -------------------MCGIAGVWNV---------------KDAFSVLHDVLLGLQH
A6LK07_THEM4      -------------------MCGIAGVWNV---------------DASYNILHDILLGLQH
PUR1_PYRAB        ----------MAKVRGMREKCGIFGVSS----------------EDAVRKTYYGLIALQH
F4B9T2_ACIHW      --------------MKIKEHCGIFATIGEN----------------SVKYTYDGLKLLQH
A4YI69_METS5      --------------MNAREHCGVFGVVGPD----------------STKLTFEGLKLLQH
F0NPQ9_SULIH      -------------MGNIHDKCGIFAVSSPKE--------------VNIQLLVEGIRLLQH
Q4J8F7_SULAC      ------------MISKIKEHCGIVGIHNVPD---------------APRIVYETLKFLQH
I0A0P7_FERFK      -----------------MLMCGISAFLDEATF------------KEAIEEIAMMLYSLQH
E0SQP0_IGNAA      -------------------MCGIAGYVG---Y------------GDTLSILLQLLIELQH
F0QVW3_VULM7      -------------------MCGIWAFLG----------------LNAGNYVVKLAPWLIH
A8MCK1_CALMQ      -------------------MCGIWAYLG----------------QGANLMVSKMAPWLMH
A8AAY0_IGNH4      ----------------------MCGVAA----------------APWADEVYVLLEGLQH
A9A5G6_NITMS      -----MDKPQHTLDDKPKENCGVIGIYSLSG-------------ANVIPMAIDALRALQH
E8R3Q7_ISOPI      -------------MGQLRHECGVAAVYHDPRATIPSPLAPDGAASRVGRLVPRMLLDMQN
L0DBH0_SINAD      -------------MGELNHECGVAAVYHAAGPAVSTLAPISGDINSVTRMIPRMLLDMQN
Q7UGS5_RHOBA      -------------MAELNHECGVAAIYHLSGRG-RSPVCTDDGPRQISRLLPRMLLDIQN
                                                                              

PUR1_ECOLI        RGQDAAGIITIDANNC----FRLRKANGLVSDVFEA-------RHMQRLQGNMGIGHVRY
PUR1_HAEIN        RGQDAAGIVTVDDENR----FRLRKANGLVSDVFHQ-------EHMLRLQGNAGLGHVRY
PUR1_PSEAE        RGQDAAGIVTCHDDK-----LYLRKDNGLVRDVFQQ-------RHMQRLIGSVGIGHVRY
M5CIZ2_STEMA      ----------------------MQKATGLVRDVFDA-------RTMSTLEGSVGIAHVRY
PUR1_YEAST        RGQDAAGIATCGSRGR----IYQCKGNGMARDVFTQ-------QRVSGLAGSMGIAHLRY
PUR1_LACKL        RGQDAAGMATCGERGR----LYQCKGNGMARDVFTQ-------HRMSGLVGSMGIAHLRY
PUR1_SCHPO        RGQDAAGIVTAGNKGR----LYQCKGSGMVADVFSQ-------HQLRQLVGSMGIGHLRY
N1PZ93_DOTSN      RGQDACGVATCSKGAK----IFQCKGNGLASKVFNEG------KRVKDLPGYMGIGHLRY
A2BTW0_PROM5      RGQDSTGIATM-ENTI----FHIHKAKGYVNTAYRT-------RDMRNLVGKIGLGHVRY
H6LAZ2_SAPGL      RGQDAAGIITFEKS------FHIKKGLGLVNDVFAQ-------RHADRLRGNIGLGHVRY
W5X8L7_BDEBC      RGQDAAGILSYDFSRSQ---FYLEKDMGLVEDVITP-------ERRARLKGTMALGHTRY
PUR1_METJA        RGQEGAGIATSDG-----KNIHYYKNIGLVTDVFKNE------TLQNLF-GYIGIGHVRY
PUR1_METTH        RGQESAGISTFNG-----NDILTHRGMGLVCDVFNPE------KLEELK-GNVGIGHVRY
PUR1_ARCFU        RGQESAGIASFD------NHIRQKRGMGLVTEVFNDE------DFELLA-GKSVIGHVRY
D1CBD4_THET1      RGQESAGIAVYDG-----NSIHTHIGMGKVREVFR-D------GPPPIQ-GKTGIGHVRY
PUR1_RAT          RGQESAGIVTSDGSS--VPKFRVHKGMGLVNHVFTED------NLKKLYVSNLGIGHTRY
PUR1_HUMAN        RGQESAGIVTSDGSS--VPTFKSHKGMGLVNHVFTED------NLKKLYVSNLGIGHTRY
PUR1_CHICK        RGQESAGIVTSDGES--SQAFKVHKGMGLINHVFNAD------SLKKLYVSNLGIGHTRY
PUR1_DROME        RGQESAGIATSEGKC--SKNFNVHKGMGMISTLFNDD------SMKKLR-GNLGIGHTRY
PUR1_DICDI        RGQESCGIATYDE----FQSVHVETGMGLVNQVFNET------NLKPLK-GKMAIGHTRY
PUR1_STAAC        RGQEGAGIVVSDQNE-----LKGERGLGLLTEAIKDD------QMERLKGYQHAIGHVRY
PUR1_STAES        RGQEGAGIVVSNHET-----LKGERGLGLLTEAIKDE------HMSNIKGYPHAIGHVRY
PUR1_BACSU        RGQEGAGIVATDGEK-----LTAHKGQGLITEVFQNG------ELSKVKG-KGAIGHVRY
PUR1_RHIEC        RGQEAAGIVSFDGKR-----FYQERHMGLVGDHYTNP------MTLARLPGSISIGHTRY
Q3YT14_EHRCJ      RGQESFGIVTSEDNK-----LYCHYSNEQVNSMFNQQ------PKINLLLGKSAIGHVRY
PUR1_SOYBN        RGQEGAGIVAVHDNH-----LQSVTGVGLVSDVFEQS-------KLSRLPGTSAIGHVRY
PUR1_SYNY3        RGQESAGIATFAGTT-----VHCHKDMGLVSQVFQES-------KLNEMVGTLAVGHTRY
PUR1_MYCTU        RGQEAAGIAVADGSQ-----VLVFKDLGLVSQVFDEQ-------TLAAMQGHVAIGHCRY
A7GHD3_CLOBL      RGEESSGISYTTSKG-----MRTKRTLGMVSNLFSKE-------DFYKMKYFSAIGHVRY
T4VR46_PARBF      RGQDSCGVAFSDKES-----IECYKGVGLVNEVFSSD-------IPTNLNGYLGIGHVRY
A5TUR7_FUSNP      RGQEGAGYTICDSITNGEVRIKTVKNVGLVSDVFKVE-------DFQRYTGNILIAHTRY
A5IMV9_THEP1      RGQESVGVVV--DGFK--TIK------GKGLVDTVLT------ED-RWEDAEKGIGHVRY
B9K970_THENN      RGQESAGVVV--DGFK--TIK------GKGLVDTVLT------ED-RWEDAEKGIGHVRY
A6LK07_THEM4      RGQESTGIIL--ENFR--IVK------EKGLVSQVLT------QK-NYIPGKIGIGHVRY
PUR1_PYRAB        RGQEGAGISVWNGRIR--TIK------GHGLVSEVFD------ENSLNLASNIAIGHVRY
F4B9T2_ACIHW      RGQESAGISYIE-DGI--KTI----KGLGLVEEALNE------KEVLQIKSKFSIGHVRY
A4YI69_METS5      RGQESAGISWIDGDRI--QTR----KGLGLVGEALDP------KEIGE--SLFSIGHVRY
F0NPQ9_SULIH      RGQESAGIAYAENGEI--LTI----KGLGLVDEVF--------KENLNKFIKNGIGHVRY
Q4J8F7_SULAC      RGQESAGITFLDKDRL--STV----KGLGLVEDALDP------IILKS--SNFSIGHVRY
I0A0P7_FERFK      RGQEAFGISVLSKDRK--FLVMRSRHQLFSLFLKSWK------KELIEKKVIGGIGHVRY
E0SQP0_IGNAA      RGQEASGIAVVTKDGR--LYVVSGK-GLVSEIFSYSH------IDIPRENVFGGIGHVRY
F0QVW3_VULM7      RGQEGVSFVCHVDG------------------SLVRL------SDVSTISSTLCLGHARY
A8MCK1_CALMQ      RGQEGFSYVCVRNG------------------ALLKV------NDPIPLESNLCLGHARY
A8AAY0_IGNH4      RGQESAGVAWVEDGE----------IKFSGGMGLVKD------AIKEAPHKGPAIGHVRY
A9A5G6_NITMS      RGQEAWGLAIPNKPP-------LKRLGLVSAASSEFK------SIAQEYSSPCVIGHVRY
E8R3Q7_ISOPI      RGQLAAGMSSFNPARP--SLLTVHKDLGTVGEAFRLNRRDVFESLMAGLDGHAAIGHVRY
L0DBH0_SINAD      RGQLAAGMTSFHPGRT--ALLKTHKEVGTVAEAFRLNHKAKFEAIMRGQDGPAAIGHVRY
Q7UGS5_RHOBA      RGQLAAGMSTFDPDRP--ALLKTRRDVGTVTEVFRLNHRAKAESLMKSLAGRAAIGHVRY
                                                                        :.* **

PUR1_ECOLI        PTAGSS-SASEAQPFYVNSPYG---ITLAHNGNLTNAHELRKKLFEEKRRHINT-----T
PUR1_HAEIN        PTAGSS-SVSEAQPFYVNSPYG---VTLVHNGNLTNSVELKEKVFKTARRHVNT-----N
PUR1_PSEAE        PTAGSS-SSAEAQPFYVNSPYG---ITLAHNGNLTNVEQLAKEIYESDLRHVNT-----N
M5CIZ2_STEMA      PTAGSE-GMDEAQPFYVNSPYG---IALAHNGNLINTEALRQQVFEQDRRNVNT-----D
PUR1_YEAST        PTAGSS-ANSEAQPFYVNSPYG---INLAHNGNLVNTASLKRYMDEDVHRHINT-----D
PUR1_LACKL        PTAGSC-ANSEAQPFYVNSPYG---ICLSHNGTLVNTLSLRSYLDEVVHRHINT-----D
PUR1_SCHPO        PTAGSC-AHSEAQPFYVNSPYG---LVLGHNGNLINGPELRRFLDTEAHRHVNT-----G
N1PZ93_DOTSN      PTAGSS-ANAEAQPFYVNSPYG---ICFAHNGNLINAPALKEYLDQTAHRHINT-----E
A2BTW0_PROM5      ATKGTAESVEEAQPFYVNAPYG---IVLIHNGNLTNTRDIEKQLFNVDKRHTNS-----S
H6LAZ2_SAPGL      TTHGSN-ELINAQPIAANYPFG---IAMVHNGNVSNFEEVHNRLYKEYHILPAT-----S
W5X8L7_BDEBC      SMRENY-DKEDLQPLFLSYPYG---IGMIHNGNVTNYDEVDEYLRKTKFRWTFS-----H
PUR1_METJA        STTGGK-AVENCQPFVVKSSFG--NIAIAHNGDLVNSDELRRELEMKGHIFTSS------
PUR1_METTH        STTGES-RIENSQPFWSEFQGG--KIAIAHNGDIINSMELREELEEEGHNFVST------
PUR1_ARCFU        STTGRS-RLENAQPFVVKSKAG--YIAVAHNGNLVNYSQLRNELENEGRVFTTD------
D1CBD4_THET1      STTGSS-CVENAGPFLVGQHPL--QMALAHNGNISNSEELKALMPDE--TFVSN------
PUR1_RAT          ATTGKC-ELENCQPFVVETLHG--KIAVAHNGELVNAARLRKKLLRHGIGLSTS------
PUR1_HUMAN        ATTGKC-ELENCQPFVVETLHG--KIAVAHNGELVNAARLRKKLLRHGIGLSTS------
PUR1_CHICK        STSGIS-ELQNCQPFVVETLHG--KIAVAHNGELTNAVRLRRKLMRHGVGLSTS------
PUR1_DROME        STAGGS-GVVNCQPFEVHTTHG--ALALAHNGELVNNESLRREVLARGVGLSTH------
PUR1_DICDI        STAGKS-TLVNAQPVIVQTLHG--QIGIVQNGNLTTAKSLRKELMQKGVGFFID------
PUR1_STAAC        ATSGNK-GIENIQPFLYHFYDM--SVGICHNGNLINAKSLRQNLEKQ-GAIFHS-----S
PUR1_STAES        ATSGNK-GIENIQPFLYHFYDM--SVGICHNGNLINAKSLRQNLEEQ-GAIFHS-----S
PUR1_BACSU        ATAGGG-GYENVQPLLFRSQNNG-SLALAHNGNLVNATQLKQQLENQ-GSIFQT-----S
PUR1_RHIEC        STTGEV-AMRNVQPLFAELEEG--GIAIAHNGNFTNGLTLRRQIIAT-GAICQS-----T
Q3YT14_EHRCJ      STSG---SKIGVQPITLDCKFG--KLAIAHNGNLTNATQIRNSLTEK-GCIFSS-----D
PUR1_SOYBN        STAGQS-MLKNVQPFLADYRFA--AVAVAHNGNFVNYRSLRARLEHNNGSIFNT-----T
PUR1_SYNY3        STTGSS-HRVNAQPAVLPTRLGP--LALAHNGNLVNTNQLREALAER-GCEDF----VTT
PUR1_MYCTU        STTGDT-TWENAQPVFRNTAAGT-GVALGHNGNLVNAAALAARARDA-GLIATRCPAPAT
A7GHD3_CLOBL      STSGNA-SIENAQPFQEETIDG--AISLAHNGNLLNYLNIKYELEKR-GNIFKS-----N
T4VR46_PARBF      STFGEI-NTLNAQPIFDNNSNC--NIALSHNGNITNIFSLKNELKKF-N--FNT-----T
A5TUR7_FUSNP      GSKNTM-SIRNCQPIGGESAMG--YISLVHNGDLLNKDELKQELLAN-GSLFQT-----G
A5IMV9_THEP1      STAGSL-EDIQPIVAFTRKG-R---LAIAHNGNIPNGEKWIEMLKEKG------AVFQSS
B9K970_THENN      STAGSL-EDIQPIVAFTRKG-R---IAVAHNGNIPNGEKWIDMLQEKG------AVFQST
A6LK07_THEM4      STFGEN-TEIQPLMGLTSKG-K---FAIAHNGNIPDAMQRMKSLIEKG------AVFNTT
PUR1_PYRAB        STSGSL-SEVQPLEVRCCGY-E---LAIAHNGTLTNFIPLRRLYEGMG------IKFHSS
F4B9T2_ACIHW      STTGKT-TLQEAQPLSNE---K---LSIAFNGTIANYFEFG----------------NYS
A4YI69_METS5      STTGST-TLQEAQPLDDG---F---IAVSFNGTITNHFQNG----------------DFS
F0NPQ9_SULIH      STSGKS-SIEEAQPLGDS---S---VVVTFNGTISNYYQFG----------------SFK
Q4J8F7_SULAC      STTGRG-VIDEAQPLSDG---K---IALAFNGTIPNYINY-----------------NVR
I0A0P7_FERFK      STTGSY-SAPSQPVLLESNDIK---FSLAFNGTIANYKELDSKLARRKGEYRISPKIKNN
E0SQP0_IGNAA      ATSGGY-MDAVTQPIAIGDRIK---IAIAFNGTIANYKLLANEYRLKV----------SS
F0QVW3_VULM7      STSGPY-GVELQPIVLGN---D---FALVFNGTISNYVELISKLRDFG-------IGIRT
A8MCK1_CALMQ      STSGPY-GVELQPVVLG----D---LALVFNGTVANYKELKMRLREMG-------IIVNS
A8AAY0_IGNH4      STSGGY-ARVQPVVTKK--------LALAFNGNIINFKFLEPSSR---------------
A9A5G6_NITMS      STMGRS-SLENAQPLKVKD------LCVAHNGTIANVQELSNLVGGCSFTPQNA------
E8R3Q7_ISOPI      ATCGGD-DLGQAQPFERHHGRTSRWFTFAYNGQLANVAQLRHDLLTTGDYHLKY-----D
L0DBH0_SINAD      ATCGGA-DRSYAQPFEREHGRTAKWFAFAFNGQLANYQELKQELLDQGDYHLKR-----D
Q7UGS5_RHOBA      ATCGAD-DRNYAQPFERRHIHKRKWFSFCFNGQLANYTLLKQRLLADGDHHLAL-----D
                                           . .  ** .                          

PUR1_ECOLI        SDSEILLNIFASEL-DNFRH--------YPLEADNIFAAIAATNRLIRGAYACVAMIIGH
PUR1_HAEIN        SDSELLLNILANHL-DHIPQ--------DHLDPQDIFYAVRKTHKDVRGAYACLAMIIGH
PUR1_PSEAE        SDSEVLLNVFAHEL-AVRNK--------LQPTEEDIFAAVSCVHDRCVGGYAVVAMITGH
M5CIZ2_STEMA      SDSEVLLNVFAFEL-DAQRQ--------LSP--EAAIRAVAGVHRRCKGGYAVVSVVLGL
PUR1_YEAST        SDSELLLNIFAAEL-EKHNK--------YRVNNEDVFHALEGVYRLCRGGYACVGLLAGF
PUR1_LACKL        SDSELLLNVFAAEL-ERHNK--------YRVNNDDIFHALEGVYRQCRGGYACVGMLAGY
PUR1_SCHPO        SDSELLLNIFAYEL-QRLDK--------FRINENDIFEALRNVYDRVNGGYACVAMIAGL
N1PZ93_DOTSN      SDSELMLNIFADEL-NVTGK--------ARVNAQDIFRALEAMYDKCKGGWACTAMLAGF
A2BTW0_PROM5      SDTEMLLNIFATELQEQIRT--------KELQPEIIFNAVKNLHKRIQGSYASIALISGH
H6LAZ2_SAPGL      NDLELLLYTFSSEL-NKKDL--------AQIGPADIFDAVSETQKKVHGAYSVIAAIANH
W5X8L7_BDEBC      NDLEILLHMTAIGL-AARKD--------RENLIENLAESIRELQQKVEGAYSAIAILADQ
PUR1_METJA        TDSEVIAQLLVRELL----------------KTSDKIEAIKNTLKKLVGAYSLLIM-FND
PUR1_METTH        TDSEVICHLLSREYD----------------EKPNMIYSIKRVSEQLVGSYSLVVL-LNQ
PUR1_ARCFU        SDTEVISQLLSKFLI----------------EEGDIINALERLNESLVGSYTMTML-VDD
D1CBD4_THET1      TDSEVVARLIIRAP------------------GSSLAEKLCSVVPMLRGAYSFVML-YDG
PUR1_RAT          SDSEMITQLLAYTPPQEQD------------DTPDWVARIKNLMKEAPAAYSLVIM-HRD
PUR1_HUMAN        SDSEMITQLLAYTPPQEQD------------DTPDWVARIKNLMKEAPTAYSLLIM-HRD
PUR1_CHICK        SDSELITQLLAFTPPLEND------------DTADWVARIKNLMNETPTSYSLLIM-HKD
PUR1_DROME        SDSELIAQSLCCAPEDVSE-----------LDGPNWPARIRHFMMLAPLSYSLVIM-LKD
PUR1_DICDI        SDVEVITQLLSNNPE-GCD-----------PHKPNWENRIAHFMSKAEAAYALCLM-TPN
PUR1_STAAC        SDTEVIMHLIRRSK------------------APTFEEALKESLRKVKGGFTFAIL-TKD
PUR1_STAES        SDTEVIMHLIRRSK------------------APTFEEALKESLRLIKGGFTFAIL-TKD
PUR1_BACSU        SDTEVLAHLIKRSG------------------HFTLKDQIKNSLSMLKGAYAFLIM-TET
PUR1_RHIEC        SDTEVVLHLIARSR------------------HASTSDRFIDAIRQMEGGYSMLAM-TRT
Q3YT14_EHRCJ      IDTEVIAHLIAINT------------------QATLLNNITNALKTINGAYSLVIL-VNG
PUR1_SOYBN        SDTEVVLHLIATSK------------------HRPFLLRIVDACEHLQGAYSLVFV-TED
PUR1_SYNY3        TDSEMIAVAIANEVD----------------KGKDWVEGTIAALTLCAGAYSLVIG-TPE
PUR1_MYCTU        TDSDILGALLAHGAA----------------DST-LEQAALDLLPTVRGAFCLTFM-DEN
A7GHD3_CLOBL      SDSEIILKFILEKIQ----------------EVREIEKAISCAIDTLKGAFSVLIL-IED
T4VR46_PARBF      SDSEVILKLIEKHFK----------------N--SIEEALCSVIKALEGGFSCVLL-TKH
A5TUR7_FUSNP      IDTEIILKFLSIYGK----------------Y--GYKEAVLRTIEKLKGCFALAMI-IND
A5IMV9_THEP1      LDSEVF--LHLISMS----------------E-GDLKESIVKALKKVPLAYSLLIL-HEE
B9K970_THENN      LDTEIF--LHLISMS----------------E-GDIKTSIVKALKKIPLAYSLLIL-HEE
A6LK07_THEM4      IDTEIF--LHYISLA----------------PYADPKLSVQWTLSRIPGAFSVLIL-TEK
PUR1_PYRAB        VDTEVIGISFLNHYS----------------QVKDEFEAMRRVFEEVKGAYSILIL-FDG
F4B9T2_ACIHW      TDTEFILDFLSKDIK----------------EGKDIVHAVKHFMDIADGAYSMVILDDKK
A4YI69_METS5      TDTEFILSFLRNQLS----------------QGRSLESSARAFMDVADGAFSLLVLSSKG
F0NPQ9_SULIH      VDTEFIYRFFKQKLT----------------F-HSIPDTVKEFMKVVDGGYSVAILLNDE
Q4J8F7_SULAC      IDTEFIYEVLKN--------------------QEDIRQGIRKLVDVADGGYSLVVLTNKG
I0A0P7_FERFK      DSITLANVLYSLYID----------------NEKDIVEALRYLPNYVIGGYSIVVETNEP
E0SQP0_IGNAA      DTEFFANAIYIETME----------------NKGDVVEALKVLAEKIIGGYSIVVLTNEP
F0QVW3_VULM7      NYDALVLAHYMRELL----------------SRRGIDDGISELFHTLRGGYSIIAIWRDS
A8MCK1_CALMQ      NYDALILAQYLKNLL----------------TRLSIDDTVNEVFKTIKGGYSILALWGNS
A8AAY0_IGNH4      WDAEALIKSIINEKT----------------KGLDLFEAARRVLERAKGSYSLVALAADG
A9A5G6_NITMS      SDTLVAAQRLVSLIS----------------ENGQMGKALSVLKNEMVGSYCFTFISDDN
E8R3Q7_ISOPI      TDTEIVMHTISHELAEVHGRAADGRDAANNNSPVDWVEVFRRASKRWDGAYNIVLLSARG
L0DBH0_SINAD      TDTEILMHLLSHELQ-------------GEGLETDWQGVFSRLADRLDGAYNIVLLSAKG
Q7UGS5_RHOBA      TDTEIILHEIARLLS-------------QSQERVDWIDVLKQVTAGFDGAYSMALLTAEG
                                                                    :         

PUR1_ECOLI        GMVAFRDPNGIRPLVLGKRD----------IDENRTEYMVASESVALDTLGFD--FLRDV
PUR1_HAEIN        GMVAFRDPFGIRPLVLGKRE----------EN-GKTDYMFASETVALDIVGFE--FVRDI
PUR1_PSEAE        GIVGFRDPNAIRPIVFGQRH----------TE-NGVEYMIASESVALDVLGFT--LIRDL
M5CIZ2_STEMA      GLVAFRDPHGIRPLVLGKRS----------HA-EGDEYIVASESAALDVLGFQ--RVRDV
PUR1_YEAST        ALFGFRDPNGIRPLLFGERE----------NPDGTKDYMLASESVVFKAHNFT--KYRDL
PUR1_LACKL        SLFGFRDPNGIRPLLFGERV----------NPDGTKDYMLASESVVLKAHNFN--KFRDL
PUR1_SCHPO        GVLGFRDPNGIRPLVIGERD----------TPEG-KDYMLASESVVLTQFGYR--TFRDI
N1PZ93_DOTSN      GLIGFRDPHGIRPMVLGERPSL--------DVQGGKDYMMASESVALSQNGYT--NIRDI
A2BTW0_PROM5      GLLAFRDPFGIRPLVIGKRIS---------QSNQKNEWMVASESLVLENNDYE--VVRDV
H6LAZ2_SAPGL      GLLAFCDPNGIRPLVLGQKE----------GPDGQPVYGFASESVCFDHLGYT--PIREL
W5X8L7_BDEBC      GMFAFCDSFGIRPMLIGRKK----------KGD-KYSYCFASEKQVFFGLDYE--YWRDL
PUR1_METJA        SLIAVRDPWGFKPLCIGRD---------------ESNIYISSEDCALTTLDAE--FVKDI
PUR1_METTH        DLYVVRDPVGIKPLAFARK---------------GSTQIVASETVAFDVIGAE--HVRDV
PUR1_ARCFU        AVIGYRDPLGFKPLCVGRI---------------DDGYVICSESCAIDALGGE--FIRDV
D1CBD4_THET1      KLYALRDPLGMRPLAFGKI---------------GDAWILASESAAIEKLGGE--YIRDV
PUR1_RAT          VIYAVRDPYGNRPLCIGRLMPVSDINDKEKKSSETEGWVVSSESCSFLSIGAR--YCHEV
PUR1_HUMAN        VIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGAR--YYREV
PUR1_CHICK        IIYAVRDPYGNRPLCIGRLIPVGDINGKGKDNSETEGWVVSSESCSFLSIGAE--YYREV
PUR1_DROME        KIYAVRDTYGNRPLCIGKIVPINAGHGNNLDTP-ADGWVVSSESCGFLSIGAR--YVREV
PUR1_DICDI        GIYGVRDSLGMRPLCLGSL----EVPCKDDPTKTITRYVLTSESCAIGTIGAK--FIRDV
PUR1_STAAC        ALYGAVDPNAIRPLVVGKMKDG--------------TYILASETCAIDVLGAE--FVQDI
PUR1_STAES        ALYGVVDPNAIRPLVVGKMENG--------------AYILASETCAIDVLGAE--FIQDI
PUR1_BACSU        EMIVALDPNGLRPLSIGMMGD---------------AYVVASETCAFDVVGAT--YLREV
PUR1_RHIEC        KLIAARDPTGIRPLVMGELDG---------------KPIFCSETCALDIIGAK--FIRDV
Q3YT14_EHRCJ      TIICCRDPAGIRPLVLGILDN---------------SYIVASETCSLDIVGAQ--FVREI
PUR1_SOYBN        KLVAVRDPFGFRPLVMGRRTNG--------------AVVLASETCALDLIEAT--YEREV
PUR1_SYNY3        GIIGVRDPHGIRPLVIGVLEEE------------TPRYVLASETCALDIIGAT--YVRTV
PUR1_MYCTU        TLYACRDPYGVRPLSLGRLDR---------------GWVVASETAALDIVGAS--FVRDI
A7GHD3_CLOBL      KLIGFRDKKGIRPLCIGKV---------------EGNYVLSSESTSINIAGGE--YIRDV
T4VR46_PARBF      ELFAFRDPNGIRPLCIGKI---------------KNSYIVCSESCVLDILGGK--FIRDI
A5TUR7_FUSNP      KLIGVRDPEGLRPLCLGKIVE-------------DDMYVLASESCALDAIGAE--FVRDI
A5IMV9_THEP1      FLAAARDPYGVRPLFYGKYGDG---------------IVVASEDAALKAIGVE--DIEEV
B9K970_THENN      FLAAARDPYGIRPLFYGRYGEG---------------VVVASEDAALKAIGVE--DVEEI
A6LK07_THEM4      MLIAARDSFGFRPLFYGKYRDG---------------YVISSEDAPLISIGAK--DITEI
PUR1_PYRAB        KIIAARDPVGFRPLVFGE-GDG---------------YYFASEDSALRMFGLE---TRDV
F4B9T2_ACIHW      RVLAVRDPKGFRPLVMGKIGES---------------IVFSSEDSAIKQLGGK--VLKDV
A4YI69_METS5      EILAMRDPRGFRPLVIGEIGDN---------------KVVSSEDSAIKQLGGR--VIGFV
F0NPQ9_SULIH      EIVIFRDPRGFHPVVLGFLEGS---------------LVVSSEDSVIRQLGGS--VLKHI
Q4J8F7_SULAC      ELIGLRDPKGFRPLVLGKLGSG---------------YIIASEDSAIRQLGGI--VIRDV
I0A0P7_FERFK      RIVIAKDPYGFRPLSYSYESG----------------FYAASENPALELIGKK--SWKEV
E0SQP0_IGNAA      RIIFAKDPRGFRPLSYVYNGDE---------------LYIASETSALETVVGG--VWREV
F0QVW3_VULM7      -LIVIRDPWGIRPLVIGSDGNG---------------IAIASESAALEALGM---TWREV
A8MCK1_CALMQ      -LIAIRDPWGLRPLAMGITNDG---------------VVFASETSVLDALGI---KWIEV
A8AAY0_IGNH4      RVLVARDPWGFRPLAYRWPH-------------------VASETAALEDIGM---TWEEL
A9A5G6_NITMS      SVFAARDPKGFRPMVLGHKESD-------------DTYIVASESSAVSAVGAK--MQRNV
E8R3Q7_ISOPI      ELVVVRDPLGIHPLCQAQDDS-------------GALWAFASESVPLTNLGFR--KVEPL
L0DBH0_SINAD      DLIVARDPLGFRPLCVAEH---------------GPLFAAASESSPLANLGFQ--NIRSL
Q7UGS5_RHOBA      EMLVARDPLGIKPMCYIHE---------------GPLFACASESVALLNLGFEPDQIRSL
                   :    *  . :*:                           **   .            :

PUR1_ECOLI        APGEAIYITEE--------------GQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKIS
PUR1_HAEIN        AAGEAVYVTFD--------------GELYSQQCAESAVLNPCIFEYVYFARPDSTIDGVS
PUR1_PSEAE        APGEAVYITEE--------------GKLYTRQCAKAPKYAPCIFEHVYLARPDSIMDGIS
M5CIZ2_STEMA      QPGEALVITAR--------------GELFSEICAEPAEHTPCIFEYVYFARPDSMIDNVS
PUR1_YEAST        KPGEAVIIPKNCSK-----------GEPEFKQVVPINSYRPDLFEYVYFARPDSVLDGIS
PUR1_LACKL        KPGEAVIIPKDCNK-----------QEPEFRQVVPTNSYRPDLFEYVYFARPDSVLDGIS
PUR1_SCHPO        RPGECVFIRRSNREDILAGFR---GPRLFSRQILPCLRFTPDIFEYVYFARPDSVIDGLS
N1PZ93_DOTSN      LPGQAVIIEK--------------GKEPEFRQVSPQLDYAPDIFEYVYFARPESEIDGIS
A2BTW0_PROM5      EPGEAIFITQN--------------GEFYSKQCSENPSLFPCAFEYVYLARPDSVMNGIS
H6LAZ2_SAPGL      KAGEIVFIDEN---------------RQLHSSLGHKTADKFCVFEFIYFAREDSELQGKL
W5X8L7_BDEBC      APGEFAFVDRD---------------LNFHSFILNQKKPRPCMFEWMYFAGSETEWHGRP
PUR1_METJA        EPGEIIEIKDGEIISHKLDYGVSEYNPVNVDVPCIYRGAATCMFEYVYFARPDSTIDGIS
PUR1_METTH        QPGEILHLNRG-----------KSYWVANAP----NTRRAHCMFEYVYFARPDSVIDGRN
PUR1_ARCFU        QPGKAAIIKDG------------ELEFVKIAK---SERRAVCIFEYIYFARPDSIIDGIS
D1CBD4_THET1      LPGELVEIGRD------------GVRSKIIAS---SDRHAFCVFEYIYFAGAATTIEGKY
PUR1_RAT          KPGEIVEISRH------------GVRTLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQM
PUR1_HUMAN        LPGEIVEISRH------------NVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQM
PUR1_CHICK        LPGEIVKISRY------------DVQTLDVVPRPEGDPSAFCIFEYVYFARPDSIFEGQM
PUR1_DROME        EPGEIVELSRS------------GYRTVDIVERPDFKRMAFCIFEYVYFARGDSIFEGQM
PUR1_DICDI        RPGEIVHINEN------------GITSF--IGRSPSDNPALCVFEYVYFSRPDSSMEGQL
PUR1_STAAC        HAGEYVVINDKG--------------ITVKSYTHHTTTAI-SAMEYIYFARPDSTIAGKN
PUR1_STAES        HAGEYVVITDEG--------------IEVKTYTRQTTTAI-SAMEYIYFARPDSTIAGKN
PUR1_BACSU        EPGEMLIINDEG--------------MKSERFSMNINRSI-CSMEYIYFSRPDSNIDGIN
PUR1_RHIEC        ENGEVIICEIQPD---------GSISIDARKPSKPQPERL-CLFEYVYFARPDSVVGGRN
Q3YT14_EHRCJ      SPGELIIIDQNN-------------TLTSSFPFKKQKSSF-CIFEYVYFARPDSIINNKS
PUR1_SOYBN        YPGEVIVVDHTG--------------IQSLCLVSHPEPKQ-CIFEHIYFALPNSVVFGRS
PUR1_SYNY3        EAGELVHITESG--------------LVSHRLAESADRKL-CVFEMIYFSRPDSVVNDES
PUR1_MYCTU        EPGELLAIDADG--------------VRSTRFANPTPKG--CVFEYVYLARPDSTIAGRS
A7GHD3_CLOBL      QPGEIVIIDKKG--------------IKSIKNEEDYCNCI-CALEYIYFSRPDSIIDGIN
T4VR46_PARBF      LPGEIIKIDNFG--------------VTTI-NASNLCKCMTCSFEYIYFSRVDSIIDGVN
A5TUR7_FUSNP      EAGEMVVIDDNG--------------VESIKYKPSTKKAS--SFEYIYFGRPDSVIDGIS
A5IMV9_THEP1      PSGTVVFFSNKG------------TETVRFSKK----EKRFCSFEFIYFARPDSHFLDQS
B9K970_THENN      PPGTVVFFTNKG------------EEKVKFSSK----ERRFCSFEFIYFARPDSHFLGQS
A6LK07_THEM4      IPGEMVIFSENG------------MEKTKFATT----KMHFCAFEYIYFSRPDSNFFYGN
PUR1_PYRAB        LPGEVFVIDGES------------YESKVLARE----KHAYCVFEYIYFARPDSTLNGIN
F4B9T2_ACIHW      LPGEIILVNPDG------------KILSDKVPS---TSFHTCAFEYIYFSRADSKIDGVS
A4YI69_METS5      HPGEIIKITRD-------------TVVRERVSS---LPTTTCAFEYIYFSRADSEIDGIS
F0NPQ9_SULIH      LPGEVITMKNG-------------KILYDKVIYEEEKNYATCSFEYIYFARPDSNIDGHS
Q4J8F7_SULAC      KPGEMIYIKNG-------------SIESEIVAR---DEVHFCSFEYIYFSRADSIIDGVS
I0A0P7_FERFK      LPGEIVSYDGGK------------LERIYSERK---VEPSPCLFEYVYFSRSDSVFNGIS
E0SQP0_IGNAA      EPGEIIVFDGTS------------IERTAARKI---YDPTPCVFEYVYFSRIDSVFNGVS
F0QVW3_VULM7      EPGKALALHGSG------------REHWVEGPR---VRRAYCALEYIYFLRPDSHFNGIS
A8MCK1_CALMQ      KPGNALVLGSNG-------------ERILNWPS---VRRMYCALEYIYFQRPDSVFNGIS
A8AAY0_IGNH4      EPNKLVMLEEGV------------PTKEAKISYD--RRKAYCAFEYVYFQRPESYFNGVN
A9A5G6_NITMS      TPGELIRMSKDG---------------IDTEMFSDDPKRAHCSFEFTYFAHPTSNMEGTN
E8R3Q7_ISOPI      PPGTLAILGP---------------EGARFERFAEPVAPKHCFFEWIYFANVASVLDDQS
L0DBH0_SINAD      EPGTMVIANR---------------TGVRTERFAASPRRAHCFFEWIYFANVASTLDDRS
Q7UGS5_RHOBA      PPGHAILIDPD--------------EGFRMERFAEPETPKHCFFEWIYFANVASTLDDRS
                    .                                        :*  *:    :      

PUR1_ECOLI        VYSARVNMGTKLGEKIARE-WEDL--DIDVVIPIPETSCDIALEIARILGKPYRQGFVKN
PUR1_HAEIN        VYAARVHMGEKLGQKIAKE-WADEIDNIDVVIPVPETSTDIALQIARVLGKPYRQGFVKN
PUR1_PSEAE        VYKARLRMGEKLADKILRE-RPDH--DIDVVIPIPDTSRTAALELANRLGVKFREGFVKN
M5CIZ2_STEMA      VHKARMRMGIKLGEKILRL-RPDH--DIDTIIPIPDTSRDAALEISNVLGVKYREGFIKN
PUR1_YEAST        VYHTRLAMGSKLAENILKQLKPE---DIDVVIPVPDTARTCALECANVLGKPYREGFVKN
PUR1_LACKL        VYHTRLQMGIKLAENVKKVVDPD---EIDVVVSVPDTARTCALQCANHLNKPYREAFVKN
PUR1_SCHPO        VYQSRLNMGEKLAHTIMKRFGPDYMEKIDAVIPVPDSARTSALALAQTAQLPYVEAFIKN
N1PZ93_DOTSN      VYRSRQLMGYRLAETIQKQLGPDVVKTIDAVIPIPETAMVSAYAVSKHLKIPESQGFVKN
A2BTW0_PROM5      VYKARLKMGDYLAETIKKTINSG---EVDVVMPIPDSSRPAAMQVARQLGIEYREGFFKN
H6LAZ2_SAPGL      VAGQRVKMGRMLAQKVREM-----GLEADMVIDVPSSGYFAASGLAEALDIPYKRGLVKS
W5X8L7_BDEBC      VYEVRLKLGEILAQECQKL-----GFDIDVVAPVPDTSRAAACRMAEVLQKPYREVLIKN
PUR1_METJA        VYKVRKRIGKILAKEHPV--------DADVVSPIPDSGVTFALGFSEESGIPYYEGLIKN
PUR1_METTH        VYRVRLNIGEALYREHPA--------NADVVVPVPDSSIPAAIGYSRASGIPYGEGLIKN
PUR1_ARCFU        VYKARSEMGKVLARESPV--------EADFVSAVPDSGITAAIGYAQESGLPYFEGLIKN
D1CBD4_THET1      VYSVRQALGRKLAQEHPVF-------DADLVGGVPDSAIPAAIAYASECGLPYEEVFIKS
PUR1_RAT          VYTVRYRCGQQLAVEAPV--------EADLVSTVPESATPAALGYATKCGLPYVEVLCKN
PUR1_HUMAN        VYTVRYRCGQQLAIEAPV--------DADLVSTVPESATPAALAYAGKCGLPYVEVLCKN
PUR1_CHICK        VYSVRRRCGQQLAIEAPV--------EADLVSTVPESATPAALGYAQKCGLPYVEVLCKN
PUR1_DROME        VYTVRLQCGRQLWREAPV--------EADIVSSVPESGTAAAHGYARESGIEFAEVLCRN
PUR1_DICDI        IHIVRQRMGETLARESPPP--QTCSNNDTIVIGVPDSSLPAAIGYAKQSGIPFTEGLTKN
PUR1_STAAC        VHAVRKASGKKLAQESPV--------NADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKN
PUR1_STAES        VHAVRKASGKRLAQENPA--------KADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKN
PUR1_BACSU        VHSARKNLGKMLAQESAV--------EADVVTGVPDSSISAAIGYAEATGIPYELGLIKN
PUR1_RHIEC        VYTTRKNMGMNLAKESPV--------DADVVVPVPDGGTPAALGYAQESGIPFEYGIIRN
Q3YT14_EHRCJ      VYEIRKNIGKELAIENPVP--K----DTHMVVPVPDSGVPAALGFSEYTKIPFEFGIIRN
PUR1_SOYBN        VYESRKKFGEILASESPV--------ECDVVIAVPDSGVVAALGYAAKAGVPFQQGLIRS
PUR1_SYNY3        LYTYRMRIGKHLAKESPV--------DADLVMGVPDSGIPAAIGFSQASGIPYAEGLIKN
PUR1_MYCTU        VHAARVEIGRRLARECPV--------EADLVIGVPESGTPAAVGYAQESGVPYGQGLMKN
A7GHD3_CLOBL      LSQFRIKCGEKLYEKYKL--------KSDIVMGVPESGNFAALGYSKASNISYSIGLIKN
T4VR46_PARBF      VYNTRFKSGVNLYNEHPV--------DADIVIGVPESGNTAALGFSKASSIPITTGFVKN
A5TUR7_FUSNP      VYDFRHQTGRCLYEQNPI--------EADIVIGVPDSGVPAGIGYAEASGIPYSAALLKN
A5IMV9_THEP1      VHIARYRMGEELYRENP--------IEADVVVPVLDSGLSGAMGFSSASGIPLDIGLMRN
B9K970_THENN      VHIARYRMGEELFRENP--------IEADVVVPVLDSGLSGAMGFSSASGIPLDIGLMRN
A6LK07_THEM4      VHKVRFKMGEILFKESN--------MKGDVVIPILDSGFSGALGFSAASKIPIELGLMRN
PUR1_PYRAB        VYCARYRMGVELARESP--------AEGDVVIAVPDSGRTAALGFAHESGIPYMEGLIKN
F4B9T2_ACIHW      VYMSRIRLGEILAKNHP--------AKADIVVPVPESSRPIAIGYSRESKIPLEEALIRT
A4YI69_METS5      VYASRIKLGELLARNHP--------ANGDVVVPVPDSSRPIALGFSRTSGIPLEEALVRT
F0NPQ9_SULIH      VYSARIRLGELLAEKHP--------ANGDIVVPVPDSSRPIALGFSRKSRIPLEEPLVRT
Q4J8F7_SULAC      VYRARVRLGEILAENHP--------AKADIVVPVPESSVPIALGFSRKSGIPLEYGLVRT
I0A0P7_FERFK      IYDARINMGRYLAEYAP--------VDGDVVIPVPDSGRVIALGYSKASGIPIEEGIVVN
E0SQP0_IGNAA      IYTSRIRMGIELAKMDN--------IEADVVIPVPDSGRAAAIGYSKASGIPIEEGIYAN
F0QVW3_VULM7      VYDARRKLGMVLAHKEGN-------HDIDIVTPVPETARIAAEAYAEGIGKPIHELIIKN
A8MCK1_CALMQ      IYSARRRLGLALARKEG--------EEVDEVSPIPETARVAAQAYANALGKPLNEFIVKN
A8AAY0_IGNH4      VHVSRVRMGMILAEEKP--------ADADVVLPVPDSGRSAAIGYSRRSGIPLDEGLVKN
A9A5G6_NITMS      IYVARKNIGRYLAKKFPIK-------DADLVIPVPDSARPAALGYAQELGVSFDEGLLKD
E8R3Q7_ISOPI      VYVSRSRLGRRLAALED----VPID-VDTIVVPVPDTAKAAADAMAYALRVPSVEGLMRN
L0DBH0_SINAD      VYLSRATLGEELARLED----VPLD-PETIVVPVPDTAKAAADAMAFALGVRSVEGLMRN
Q7UGS5_RHOBA      VYLSRTNLGRELATAEREFGRVPLDDPDTIIVPVPDTSKAAADSMAYELSIPCREGLIRN
                  :   *   *  *                  :  : . .   .   :          :   

PUR1_ECOLI        RYVGRT---FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMARE
PUR1_HAEIN        RYVGRT---FIMPGQAQRISSVRRKLNTIKAEFKDKNVLLVDDSIVRGTTSEQIVEMARS
PUR1_PSEAE        RYIGRT---FIMPGQAARKKSVRQKLNAIELEFRGKNVMLVDDSIVRGTTCKQIIQMARE
M5CIZ2_STEMA      RYIGRT---FIMPGQGERVKSVRRKLNPIHLEFRNRVVLLVDDSIVRGTTSQQIVQMARD
PUR1_YEAST        RYVGRT---FIMPNQRERVSSVRRKLNPMESEFKGKKVLIVDDSIVRGTTSKEIVNMAKE
PUR1_LACKL        RYVGRT---FIMPNQKERVSSVRRKLNPMDFEFKDKRVLIVDDSIVRGTTSKEIINMAKE
PUR1_SCHPO        RYIGRT---FIMPGQQIRRKSVRRKLNVQPQEFFDKNVLIVDDSIVRGTTSREIVQMARE
N1PZ93_DOTSN      RYIFRT---FIMPNQTARQRGVRAKLNAIPIEFKDKNVLLVDDSIVRGTTSREIVQMARE
A2BTW0_PROM5      RYVGRT---FIMPGHQKRKQSVRQKLNAMSTEFKNKNVLIVDDSIVRGTTSKQIVQMAKD
H6LAZ2_SAPGL      NYIGRS---FISPSQVEREALVKRKLNPIARTIKGKKLLVVDDSIVRGTTSKRIVQILRE
W5X8L7_BDEBC      RYVHRS---FIVNQPELRQIMVNLKLSPVETEIRGKNILLVDDSIVRGTTSMRIVRLLKS
PUR1_METJA        RYVGRT---FILPSQNERELAVRLKLSPVKSVLEGKRVVLVDDSIVRGTTSRRIVNMVRK
PUR1_METTH        RYVGRT---FIMPTQEERETAVKLKMNPIRSELEGKRIVLIDDSIVRGTTSRALIDIIRD
PUR1_ARCFU        RYVGRT---FIMPVQSLRETSVRLKVNVVRENVRGRRVVLVDDSIVRGTTSRRIVQMIKD
D1CBD4_THET1      RYAERS---FIKPDQRLRRLEVDLKFSIVKPNVEDKKIVIVDDSIVRGNTMKRAVSALRR
PUR1_RAT          RYVGRT---FIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKE
PUR1_HUMAN        RYVGRT---FIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKE
PUR1_CHICK        RYVGRT---FIQPNMRLRQLGVAKKFGVLSDNFKGKRVVIIDDSIVRGNTISPIIKLLRE
PUR1_DROME        RYVGRT---FIQPSTRLRQLGVAKKFGALSENVAGKRLVLIDDSIVRGNTIGPIIKLLRD
PUR1_DICDI        RYIHRT---FIQPSDHLRQQGIKLKFNPLTENIQGKKVILVDDSIVRANTIKALIKLIRG
PUR1_STAAC        QYVART---FIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKD
PUR1_STAES        QYVART---FIQPTQELREQGVRVKLSAVKDIVDGKDIVLVDDSIVRGTTIKRIVKMLKD
PUR1_BACSU        RYVGRT---FIQPSQALREQGVRMKLSAVRGVVEGKRVVMVDDSIVRGTTSRRIVTMLRE
PUR1_RHIEC        HYVGRT---FIEPTQQIRAFGVKLKHSANRAMIEGKRVVLVDDSIVRGTTSLKIVQMIRE
Q3YT14_EHRCJ      HYVGRT---FIQPSNYVRNMGVKLKHNANASILKDKIIILIDDSLVRGTTLKNIITLLHK
PUR1_SOYBN        HYVGRT---FIEPSQKIRDFGVKLKLSPVHAVLEGKRVVVVDDSIVRGTTSSKIVRLLKE
PUR1_SYNY3        RYVGRT---FIQPTQHMREHGIRMKLNPLKDVLAGKRIIIVDDSIVRGTTSRKIVRALRE
PUR1_MYCTU        AYVGRT---FIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRGNTQRALVRMLRE
A7GHD3_CLOBL      SYVGRN---FIKATEKERKRDINIKINAIKSIVQDKSVIVIDDSIVRGTSSKKVVSALRK
T4VR46_PARBF      NFLGRS---FIKPSQSKRCETVNLKLNVIKENVKSKKVVVVDDSIIRGTTCKKIVSILKD
A5TUR7_FUSNP      KYVGRT---FIAPVQELRERAVRVKLNPIKELIKGKRVVVIDDSIVRGTTSKKLIDVLFE
A5IMV9_THEP1      RYVGRS---FIMPVD--REKIVKKKLVPIEDVVSGKRVVVIDDSIVRGTTMGIIVKILRE
B9K970_THENN      RYVGRS---FIMPVD--REKIVKKKLVPIEDVVRGKRVVVIDDSIVRGTTMGIIVKILRE
A6LK07_THEM4      RYLGRS---FIMPEK--REEIVKRKLIPIPQVIKDKEVVLIDDSIVRGTTMKQIVKMLRE
PUR1_PYRAB        RYIGRT---FIMPSG--RGLKVKLKLSPVREVVNGKRVVLVDDSIVRGTTMTRIVKMLRD
F4B9T2_ACIHW      IVSKRS---FIMPTNDKRKSVLEEKFGIVEDAVKGKRIVLIDDSIVRGNTMKRIIMLLRN
A4YI69_METS5      ISSKRS---FIMPSDEKRNEVLKEKFGIVEWAVRGKRVVLVDDSIVRGNTMKRIVNSLRS
F0NPQ9_SULIH      ISSVRS---FIMPTQDKRNEVLEEKFGVVVDAVRDKRIVLIDDSIVRGNTMKRIISMLRN
Q4J8F7_SULAC      SVSKRS---FIMPSQDKRESIVEEKFGVVGEVVRNKKIILIDDSIVRGTTMKKLVKLIRE
I0A0P7_FERFK      KYLGRG---FITPPF-QRPLVTKIKYNIVEEAVRGKEVVLIDDSIVRGTTMSDLVPKLKL
E0SQP0_IGNAA      KYLGRG---FITPPH-IRDYVSRLKYGFIKSVVDGKKVVLVDDSIVRGTTMRSIVLRLRE
F0QVW3_VULM7      RYVGRS---FIKPPR-ERS---VNMYNVIRDIVKGRSISLVDDSIIRGDTFRKVLPRFRR
A8MCK1_CALMQ      RFMGRG---FIKPPK-DRD---FELYSVIKEGVTGKSVALIDDSIIRGTTLRRIIPKVKA
A8AAY0_IGNH4      RYLGRS---FIMPPG-LREVIAMKKYGVVKEVVEGKRVVVVDDSIVRGTTMKRIVKLLKE
A9A5G6_NITMS      RYSKKGPLRSFIEPHQTDRVEINRWIIPIREIIDGKHVVVIDDSLVRGTSSKAIIKALRR
E8R3Q7_ISOPI      RYLGRT----FIEGNADRATRAKLKYTPIPEVLQGKRVLLVEDSIVRSTTLRALVHEMRT
L0DBH0_SINAD      RYVGRT----FIEGTADRAAKARLKYTPLPEVLAGKRVLLVEDSIVRSTTMRALVHEIRD
Q7UGS5_RHOBA      RYAGRT----FIEGGRARKAKAAAKYTPLREVLQGKRVILVEDSIVRSTTMNALLDRIRD
                      :     :                     . .: : :::**::*. :    :     

PUR1_ECOLI        -AGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHGRE--------------VDEIRQII
PUR1_HAEIN        -AGAKKIYFASAAPEIRYPNVYGIDMPSRDELIAYGRN--------------VDEIAELI
PUR1_PSEAE        -AGAKNVYFCSAAPAVRYPNVYGIDMPSAHELIAHNRS--------------TEDVSKLI
M5CIZ2_STEMA      -AGARKVYLASAAPPVRFPNIYGIDMPAAEELVAHNRT--------------VEEIEAHL
PUR1_YEAST        -SGATKVYFASAAPAIRYNHIYGIDLTDTKNLIAYNRT--------------DEEVAEVI
PUR1_LACKL        -SGATKVYFASAAPAIRFNHIYGIDLADTKQLVAYNRT--------------TDEVAQEL
PUR1_SCHPO        -SGAKNVYLASCAPMITHPHVYGIDLADCKDLIAYGKT--------------EDEVAEAI
N1PZ93_DOTSN      -AGAKKVYFSSCAPPVTHSHIYGIDLASRNELVAHGRT--------------SKDIAEHI
A2BTW0_PROM5      -AGANKVFFTSAAPPVRFPHVYGINMPNRDELIAHDRT--------------IAEIAKKL
H6LAZ2_SAPGL      -AGAEKVYFVSAAPAIKHPCIYGIDMSVSTELLAVGRS--------------DEEICDYI
W5X8L7_BDEBC      -AGAKKVYLASTSPPIKHPCYYGIDFPKHESLIAHRHS--------------EKEMMKLL
PUR1_METJA        -AGAKEVHLRIGCPKIISPCYYGIDMATKKELIASNKT--------------EEEIGKAI
PUR1_METTH        -AGAEEIHLRIGCPPIKSPCYYGIAMATKKELIASTRN--------------VEEIRRII
PUR1_ARCFU        -AGAKEVHMRIGSPPIIAPCYFGIDMKSREELIAASHT--------------VEEIGRIF
D1CBD4_THET1      -YGAKEVHLRITSPPLKHPCYYGIDIKSDEDLIAAHST--------------VQEIADYI
PUR1_RAT          -SGAKEVHIRVASPPIKHPCFMGINIPTKEELIANKPE--------------FEYLAEYL
PUR1_HUMAN        -SGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPE--------------FDHLAEYL
PUR1_CHICK        -SGAKEVHIRVASPPIRFPCYMGINIPTKEELIANRPE--------------FHDLANYI
PUR1_DROME        -AGAREVHIRIASPPLQYPCYMGINIPTREELIANKLN--------------PDQLARHV
PUR1_DICDI        -AGATEIHVRISSPPVLHPCHMGIDMATYDQLIGHNRT--------------VEEIREYI
PUR1_STAAC        -SGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKS-------------PEE-IKDYI
PUR1_STAES        -SGANRIHVRIASPEFMFPSFYGIDVSTTAELISASKS-------------PEE-IKNHI
PUR1_BACSU        -AGATEVHVKISSPPIAHPCFYGIDTSTHEELIASSHS-------------VEE-IRQEI
PUR1_RHIEC        -AGAREVHIRVASPMIFFPDFYGIDTPDADKLLANQYA-------------DVEAMAKYI
Q3YT14_EHRCJ      -AQVKEIHLRISSPPTINSCFYGIDTPEESKLIANKLS-------------TTE-IKNEL
PUR1_SOYBN        -AGAKEVHMRIACPPIVASCYYGVDTPSSEELISNRMS-------------VEE-IRKFI
PUR1_SYNY3        -AGATEVHMRISSPPVTHPCFYGIDTDSQDQLIAARL--------------TVAEIAEQI
PUR1_MYCTU        -AGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENED---------EMLEAVRHAI
A7GHD3_CLOBL      -AGAREVHFMVASPKINYYCNLGIDIKSKKELLSFQKT--------------KEEMRKFI
T4VR46_PARBF      -AGAKEIHYRVASPIVTSPCCLGINT-SKSELIGSTMT--------------LNEIANFI
A5TUR7_FUSNP      -AGAKEVHFRSASPVVIEESYFGVNIDPNNKLMGSYMS--------------IEEIRKAI
A5IMV9_THEP1      -AGAKEVHVGIHSPPVRFPCFYGIDTARKKELVAGERA--------------VEEVKKIV
B9K970_THENN      -AGAREVHVGIHSPPVRFPCYYGIDTARKKELVAGERD--------------VEEVKKIV
A6LK07_THEM4      -NGAKKVKVGIHSPPVIGPCPYGIDTSRKNELIASQKK--------------LDEIIKEI
PUR1_PYRAB        -AGAREVHVRIASPPIRYPCYMGIDIPTRHELIAAWRS--------------IEDIRKEI
F4B9T2_ACIHW      -SGAKEIHVRVGSPMIKYPCYMGIDFPSRSELIASNKD--------------ENEIAKIL
A4YI69_METS5      -AGAREVHIRIGSPMIRFPCYMGIDFPRRSELVANIGD--------------ERAIAREL
F0NPQ9_SULIH      -AGAKEIHVRIGSPMIKYPCYMGIDFPKREELIAHNKS--------------EREIGNEL
Q4J8F7_SULAC      -NGASEIHVRIGSPMIRYPCYMGIDFPNKKELIANDKN--------------EMEIAKSI
I0A0P7_FERFK      -KGAKKVHIRIGSPPYKCPCYMGIDVPTKSEVIAKNDE---------------KVIAKMI
E0SQP0_IGNAA      -AGASEVHVRIASPPFRYPCFMGIDVASRQELLAWSSMT-------------LEDIRKSI
F0QVW3_VULM7      -SGTRAIHVRVSSPPIRYPCFMGMDFPTRRELVAHGRS--------------IDEVRGYL
A8MCK1_CALMQ      -AGAKAIHVRVSSPPVRYPCFMGMDFPSRRELIAHGKS--------------IGEVKSML
A8AAY0_IGNH4      -KGAEEVHVRIASPPVRAPCYMGIDFPSREELVAAERG--------------EEELSELW
A9A5G6_NITMS      -AGARKISMVITYPPIKFPCYAGIDFPSQEELATFSNGKDLN------DEETIDMVRKDI
E8R3Q7_ISOPI      RGGAREIHLRVACPPIVAPCYYGIDMSTTDELFAPKFGLPDELENGGYPREVLDRMAREL
L0DBH0_SINAD      RGGAREIHLRVACPPIIAPCFYGIDMSRRDELFATKFLNAPD---GRISIEDQDRMAQEL
Q7UGS5_RHOBA      VGGAKEIHVRVACPPIVAPCFYGIDMSTIDQLIAPKYFSLTG----ELDEESQQRMADDL
                     .  :      *        *:      .:                       :    

PUR1_ECOLI        GADGLIFQDLNDLIDAVRAE-------------------------NPDIQQFECSVFNGV
PUR1_HAEIN        GVDKLIFQDLTALTESVQLE-------------------------NPAIQGFDCSVFTGE
PUR1_PSEAE        GADWLVYQDLPDLIDAVGGG-------------------------KIKIDHFDCAVFDGE
M5CIZ2_STEMA      GCDWLIYQDLEDMEAAVSEG-------------------------NPALRNFDSSCFNGH
PUR1_YEAST        GCERVIYQSLEDLIDCCKTD---------------------------KITKFEDGVFTGN
PUR1_LACKL        GCEKVIYQSLEDLVDCCKTD---------------------------KIDKFEVGVFTGN
PUR1_SCHPO        SADGVIYQTLEDLLDSCRTA---------------------------ELTEFEVGLFTGE
N1PZ93_DOTSN      GADDVIYQSLDDLTSACAQQSPR----------------------DPKTQRFEVGVFCGK
A2BTW0_PROM5      EIDNLVYQSVDNLRKSIIND--------------------------SSVKDLEMSCFTGS
H6LAZ2_SAPGL      GADALIYQKLEDLKAIFEHA------------------------------GFCMACLDGA
W5X8L7_BDEBC      EVDGLLFLPQERLKEAIGLP------------------------------SLCMACVDGD
PUR1_METJA        GVDSIGYLSLEGLVKAIGRKD------------------------------LCLACVTGK
PUR1_METTH        GVDSLGYLSIESLVECIGIKKGF----------------------------LCTGCLDGD
PUR1_ARCFU        GTDSLAYLSLEGLLEAVRRAGGKR--------------------------GYCLACLTSK
D1CBD4_THET1      GVDSLGYLSLQGLAEVITDKLGQE--------------------------ALSLFHATHC
PUR1_RAT          GANSVVYLSVEGLVSSVQQEIKFKKQKVKKRDITIQENGNGLEYF--EKTGHCTACLTGQ
PUR1_HUMAN        GANSVVYLSVEGLVSSVQEGIKFKKQKEKKHDIMIQENGNGLECF--EKSGHCTACLTGK
PUR1_CHICK        GADSVVYLSVEGLVSSVQESIKARKENEN--SLKTQKSR-----V--GKIGHCTACLTGD
PUR1_DROME        GADSLAYLSVEGLVEAVQLKHRDAGDSKS------------------KGTGHCTACLTGE
PUR1_DICDI        GAESLQYLTLEGLMKSVNIGIKPQAETNSTPCFSTSSPTTTKIKINENNQKHCVACFTGD
PUR1_STAAC        GADSLAYLSVDGLIESIGLDYDAP------------------------YSGLCVESFTGD
PUR1_STAES        GADSLAYLSVDGLIESIGLDYDAP------------------------YHGLCVESFTGD
PUR1_BACSU        GADTLSFLSVEGLLKGIGRKYDDS------------------------NCGQCLACFTGK
PUR1_RHIEC        GADSLAFLSINGLYRAVGGEDRNPA-----------------------RPQFTDHYFTGD
Q3YT14_EHRCJ      GCDSIYFLSINGLYKAINNTTRNNS-----------------------SPQYCDACFTGD
PUR1_SOYBN        GSDSLAFLPLDKLKTLLGDDALN----------------------------YCYACFSGK
PUR1_SYNY3        EVDSLAYLSQEGMLLCTGEDISH----------------------------FCSACFNGR
PUR1_MYCTU        GADTLGYISLRGMVAASEQPTSR----------------------------LCTACFDGK
A7GHD3_CLOBL      GADSLEFLSLIDMEQCLNKS------------------------------NICTGCFDGS
T4VR46_PARBF      GADSLGYLSVSGFLNTLPKNK-----------------------------TTCLKCFL--
A5TUR7_FUSNP      GATTLDYLSLKNLKKILNGGD-----------------------------DFYMGCFKED
A5IMV9_THEP1      NADSLFYLSLEGLKRAIGRSE------------------------------LCVACFSGE
B9K970_THENN      NADSLFYLSLEGLKRAIGRNE------------------------------LCVACFSGE
A6LK07_THEM4      NADELHYLSIDGLKKAIGGDN------------------------------LCLGCLNLN
PUR1_PYRAB        GADSLAYLSIEGLKRAVGTKN------------------------------LCMACLTGE
F4B9T2_ACIHW      GADSIEYLTVDEMKQAIGRDS------------------------------LCTACFTGI
A4YI69_METS5      NADSVEYLSVEEMVQAIGRTT------------------------------LCKACFTGE
F0NPQ9_SULIH      NADSIEFLSVEEMVQAIGRRD------------------------------LCNACFSGV
Q4J8F7_SULAC      GADSVEYLSIDEMIKAIGRQD------------------------------LCHACFSGM
I0A0P7_FERFK      GADSLIYNSLDNLIKAVPLRN------------------------------LCHACFSCK
E0SQP0_IGNAA      GADSILYNTVDALTRAVGLCS------------------------------LCTACFTGR
F0QVW3_VULM7      GADSLVYLTVDELMDSIGTTE------------------------------LCTACFTGN
A8MCK1_CALMQ      GSDSLTYLTVDELKEAIGTVE------------------------------LCTACFTGE
A8AAY0_IGNH4      GADSVGYLSVEGLRRAIGLEE------------------------------LCVACFTDV
A9A5G6_NITMS      GADFLGYNDAENLAAAVGIPADS----------------------------MCFTCASGN
E8R3Q7_ISOPI      GADSLRYLSVSSLAEAIGKPVSH----------------------------LCRACVTGN
L0DBH0_SINAD      GADSLRYLPVEAIARAVSMSSDQ----------------------------LCRACITGQ
Q7UGS5_RHOBA      GADSLQYLPVSAIARAINLPEEH----------------------------LCQACVTGK
                      : :     :                                               

PUR1_ECOLI        YVTKDVDQGYLDFLDTLRNDDAKAVQ----------------------------------
PUR1_HAEIN        YITGDISPEYLEKIATQRNDNAKKK-----------------------------------
PUR1_PSEAE        YVTGDVNEAYLNRIEQARNDATKAK-----------------------------------
M5CIZ2_STEMA      YPTG-IEPGYFERIQQLRSDDAKHK-----------------------------------
PUR1_YEAST        YVTG-VEDGYIQELEEKRESIAN-------------------------------------
PUR1_LACKL        YVTG-VEDGYLQELERVRALNKA-------------------------------------
PUR1_SCHPO        YTTG-ASKEYLVHLEQMRIANNR-------------------------------------
N1PZ93_DOTSN      YVTP-VDQEYFDHLERIRGETKKMKVMEKAVEAVAHGNATQRDIKLALNGADVDNHGEVV
A2BTW0_PROM5      YVTGTVNHEYLKWVENEYKS----------------------------------------
H6LAZ2_SAPGL      YPTPAAKEALAQIEAERLAIKK--------------------------------------
W5X8L7_BDEBC      YPVPVSSEEFLKSRRFNIGGDGKSEVPL--------------------------------
PUR1_METJA        Y----PTEV-----NFEKILGRE-------------------------------------
PUR1_METTH        Y----PTPLPSDISEYEAMRSCSR------------------------------------
PUR1_ARCFU        Y----PVSVPGE--ECEC------------------------------------------
D1CBD4_THET1      YGCFDAVGYPYSKLSPEPAYSSST------------------------------------
PUR1_RAT          YPV----DLEW-------------------------------------------------
PUR1_HUMAN        YPV----ELEW-------------------------------------------------
PUR1_CHICK        YPV----ELEW-------------------------------------------------
PUR1_DROME        YPGGLPDELSW-------------------------------------------------
PUR1_DICDI        YPC----SLDF-------------------------------------------------
PUR1_STAAC        YPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV---------------------
PUR1_STAES        YPAGLYDYEKNYKKHLSERQKSYIANNKHYFDSEGNLHV---------------------
PUR1_BACSU        YPTEIYQ-----DTVLPHVKEAVLTK----------------------------------
PUR1_RHIEC        YPTRLLDKNGESMGNKLSMLASNG------------------------------------
Q3YT14_EHRCJ      YPIGKIE-----------------------------------------------------
PUR1_SOYBN        YPVEPEELQMKRLGVAHFNWDDDFNGNFESIDVGGWVTNQDGFKIGSV------------
PUR1_SYNY3        YPITVPDAVRRSKLMLENITA---------------------------------------
PUR1_MYCTU        YPIELPRETALGKNVIEHMLANAARGAALGELAADDEVPVGR------------------
A7GHD3_CLOBL      YANY--------------------------------------------------------
T4VR46_PARBF      ------------------------------------------------------------
A5TUR7_FUSNP      E-----------------------------------------------------------
A5IMV9_THEP1      YLHE--------------------------------------------------------
B9K970_THENN      YFHD--------------------------------------------------------
A6LK07_THEM4      YPI---------------------------------------------------------
PUR1_PYRAB        YPEWAFNF----------------------------------------------------
F4B9T2_ACIHW      YPLKRNYSLQVMESVFNR------------------------------------------
A4YI69_METS5      YPLKGKYDLSALESVFAR------------------------------------------
F0NPQ9_SULIH      YPLKFKYNSTELERVFGK------------------------------------------
Q4J8F7_SULAC      YPLKHSYDFSKLSVSMKG------------------------------------------
I0A0P7_FERFK      YPFSEKSSCEYIKMLIDRGGRNEI------------------------------------
E0SQP0_IGNAA      YPFNGYTASDLENMFSR-------------------------------------------
F0QVW3_VULM7      YPFTINIDESEKAFSGDRVWESQAL-----------------------------------
A8MCK1_CALMQ      YPFKVNIDELEGAFTGDR------------------------------------------
A8AAY0_IGNH4      YPFPISEEEVRSMLKAHKA-----------------------------------------
A9A5G6_NITMS      YDSLGITPEFKSREEIKGEAS---------------------------------------
E8R3Q7_ISOPI      YPTPTGAELYRINAQQVPACSVSGADTTQAIRSGSAREAGSSSSRSGRRAYETSAPLGTG
L0DBH0_SINAD      YPSNAGQKLYQLDI------------------SGGSKNKGAN----GKRAYEMTASSTTR
Q7UGS5_RHOBA      YPTPIGQHLYQIACD-----------------NRGARVN-------NQRTYEQLAAAVAG
                                                                              

PUR1_ECOLI        ----------------------------------------RQNEVENLEMHNEG------
PUR1_HAEIN        ----------------------------------------REKQASNLEIYNEQ------
PUR1_PSEAE        ----------------------------------------SQAVSAIIDLYND-------
M5CIZ2_STEMA      ----------------------------------------RRA-----------------
PUR1_YEAST        ------------------------------NSSDMKAE-------VDIGLYNCADY----
PUR1_LACKL        ------------------------------KLTTAKAE-------VDIGLYNSADY----
PUR1_SCHPO        ------------------------------ARKHSFAEDEEREAPEDISLHNTHSDVTFD
N1PZ93_DOTSN      ARDSGSDGEGRLPKKEVRDRISRGNSFVAARNSSRPANGQERSESQDIALHNINDHGGES
A2BTW0_PROM5      ------------------------------------------------------------
H6LAZ2_SAPGL      ------------------------------------------------------------
W5X8L7_BDEBC      ------------------------------------------------------------
PUR1_METJA        ------------------------------------------------------------
PUR1_METTH        ------------------------------------------------------------
PUR1_ARCFU        ------------------------------------------------------------
D1CBD4_THET1      ------------------------------------------------------------
PUR1_RAT          ------------------------------------------------------------
PUR1_HUMAN        ------------------------------------------------------------
PUR1_CHICK        ------------------------------------------------------------
PUR1_DROME        ------------------------------------------------------------
PUR1_DICDI        ------------------------------------------------------------
PUR1_STAAC        ------------------------------------------------------------
PUR1_STAES        ------------------------------------------------------------
PUR1_BACSU        ------------------------------------------------------------
PUR1_RHIEC        ------------------------------------------------------------
Q3YT14_EHRCJ      ------------------------------------------------------------
PUR1_SOYBN        ------------------------------------------------------------
PUR1_SYNY3        ------------------------------------------------------------
PUR1_MYCTU        ------------------------------------------------------------
A7GHD3_CLOBL      ------------------------------------------------------------
T4VR46_PARBF      ------------------------------------------------------------
A5TUR7_FUSNP      ------------------------------------------------------------
A5IMV9_THEP1      ------------------------------------------------------------
B9K970_THENN      ------------------------------------------------------------
A6LK07_THEM4      ------------------------------------------------------------
PUR1_PYRAB        ------------------------------------------------------------
F4B9T2_ACIHW      ------------------------------------------------------------
A4YI69_METS5      ------------------------------------------------------------
F0NPQ9_SULIH      ------------------------------------------------------------
Q4J8F7_SULAC      ------------------------------------------------------------
I0A0P7_FERFK      ------------------------------------------------------------
E0SQP0_IGNAA      ------------------------------------------------------------
F0QVW3_VULM7      ------------------------------------------------------------
A8MCK1_CALMQ      ------------------------------------------------------------
A8AAY0_IGNH4      ------------------------------------------------------------
A9A5G6_NITMS      ------------------------------------------------------------
E8R3Q7_ISOPI      ------------------------------------------------------------
L0DBH0_SINAD      SAT---------------------------------------------------------
Q7UGS5_RHOBA      Q-----------------------------------------------------------
                                                                              

PUR1_ECOLI        --
PUR1_HAEIN        --
PUR1_PSEAE        --
M5CIZ2_STEMA      --
PUR1_YEAST        --
PUR1_LACKL        --
PUR1_SCHPO        FV
N1PZ93_DOTSN      --
A2BTW0_PROM5      --
H6LAZ2_SAPGL      --
W5X8L7_BDEBC      --
PUR1_METJA        --
PUR1_METTH        --
PUR1_ARCFU        --
D1CBD4_THET1      --
PUR1_RAT          --
PUR1_HUMAN        --
PUR1_CHICK        --
PUR1_DROME        --
PUR1_DICDI        --
PUR1_STAAC        --
PUR1_STAES        --
PUR1_BACSU        --
PUR1_RHIEC        --
Q3YT14_EHRCJ      --
PUR1_SOYBN        --
PUR1_SYNY3        --
PUR1_MYCTU        --
A7GHD3_CLOBL      --
T4VR46_PARBF      --
A5TUR7_FUSNP      --
A5IMV9_THEP1      --
B9K970_THENN      --
A6LK07_THEM4      --
PUR1_PYRAB        --
F4B9T2_ACIHW      --
A4YI69_METS5      --
F0NPQ9_SULIH      --
Q4J8F7_SULAC      --
I0A0P7_FERFK      --
E0SQP0_IGNAA      --
F0QVW3_VULM7      --
A8MCK1_CALMQ      --
A8AAY0_IGNH4      --
A9A5G6_NITMS      --
E8R3Q7_ISOPI      --
L0DBH0_SINAD      --
Q7UGS5_RHOBA      --