CLUSTAL format seed alignment for MF_01972
_____________________________________________________________________________
Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
T23O2_RALN1 ------------------------------------------------------MKPMSY
T23O_SORC5 -----------MRPVPGPSVFWGAGSRLPAPLVARAHRLLRTRRANPARGASRITKDMNY
D0LHK4_HALO1 ----------------------------------------------------MTRDVTTY
T23O_ANADE -----------------------------------------------MTDPSAHSAALTY
T23O_HERA2 -----------------------------------------------------MSQALTY
T23O_BRADU -------------MTSSDYDPAS-----------------------EGAETDF-SRRMSY
Q9RYH4_DEIRA -----MSGEPSCPFGGPAPEHSA-----------------------EQAHRDF-SRSLSY
T23O_BURPS -------MQP--PGDDAAPRCPFAGAHAPDAPHVPEAAGDDAQAGWHRAQLDF-SQSMSY
T23O1_RALN1 ------MSEPIQPTRPAASGCPMHGAQA---------------ESWHDAQMDF-SKSMSY
T23O_BORPE -------------MQPTPTQRPEAIVHD------------------EKAQLDF-ARDMSY
T23O_PSEAE -------------MCPCPHSQAQGETDG--------------EAEWHNAALDF-THAMSY
T23O_PSEFL -------------MCPCPYMHQAKPQ------------------QWHDAKLDF-AESMSY
T23O_BACAN -------------MKENEKVIME-----------------------KGIHTDF-KENMTY
Q81CK2_BACCR ----------MANMKENEKVIME-----------------------KGIHTDF-KENMTY
T23O_CAUVC ----------------------------------------------------M-AQDMTY
T23O_XANCP -------------MPVDKNLRDLE----------------------PGIHTDL-EGRLTY
D7AZD8_NOCDD -------------MLTTTAQQCPYAGGPGGAE-------AARSAGDDSPTLSF-DRATPY
D7BWH7_STRBB -------------MRPNTHQPAS-------------------------------DGETPY
Q9X8R3_STRCO -------------------------------------------MSHDAPNLDF-EGSTPY
D2AYJ2_STRRD ---------MEVNNLKESLMTSTRQLSERERE-------TRAAANEGLPTLGF-DAATPY
B0T9I9_CAUSK MTRKRILPQIRSPELELSLVRDIDASTDATRR-------ANVVQTGGEPIVAFAETSNPY
G1MAF5_AILME --------------MSGCPFLGNNFGCAF---KKLSIEGNEEDESQTGVNRASKG-GLIY
H0WPN4_OTOGA --------------MSGCPFLGNNLRYAF---QKLPVEGSEEDISQGGVNRASKG-GLIY
T23O_HUMAN --------------MSGCPFLGNNFGYTF---KKLPVEGSEEDKSQTGVNRASKG-GLIY
G1R355_NOMLE --------------MSGCPFLGNNFGYTF---KKLPVEGSEEDKSQTGVNRASKG-GLIY
T23O_BOVIN --------------MSGCPFLGKSFGYAF---KPLSAQGSEEDKSQAGVNRASKG-GLIY
T23O_MOUSE --------------MSGCPFAGNSVGYTL---KNVSMEDNEEDRAQTGVNRASKG-GLIY
T23O_RAT --------------MSGCPFSGNSVGYTL---KNLSMEDNEEDGAQTGVNRASKG-GLIY
G1PKL2_MYOLU --------------MSGCPFLRNDFEYDL---RKLSLEGNEEDKSQTGVNKASKG-GLIY
T23O_XENTR --------------MSGCPFMGKKHHFNF---SELSLEDKNEDSSQEGLNKASKG-GLIY
T23OA_DANRE --------------MSGCPYFQRKFLSTS---KQHLKE-EENDEAQTGINKASKG-GLIY
T23OB_DANRE --------------MSGCPFLGGTLQLLS---SNPRQA-EEEDGSQGGVNKAAKG-GIIY
T23O_AEDAE ---------------MSCPVGNH-----------------NGDP-QGGQRLGSEA-GMLY
T23O_ANOGA ---------------MSCPMRSG-----------------FVDSVQGGHHLGSEA-GMLY
T23O_DROME ---------------MSCPYAGN-----------------GNDHDDSAVPLTTEV-GKIY
T23O_DROPS ---------------MSCPYAGN-----------------GNDHDDAAVPLSTEV-GKIY
E0VBN6_PEDHC -----------MVYLFICIFKEK-----------------YIDSGQDGECLGEQS-GMLY
E9G9M1_DAPPU -------------------------------------------------MAEHST-GMMY
T23O_CAEBR ---------------MACPYMNGGDTLPH---RVTFME--GGEECQQGVNKVEMGFGQTY
T23O_CAEEL ---------------MACPYLGSG-ELTH---RVTFME--GGEECQQGVNKVEMGFGQTY
T23O_DICDI --------------MSGCQFNQPYCPRSE-EKKSIAESIEKATLMEPSIDAQSAQKGVYY
F0ZW87_DICPU --------------MSGCQFHQPYVNNNENEKKTIAESIEKATLMDPALDAHKAQKGVYY
*
T23O2_RALN1 WDYIKVEELLALQGGANGD-ETQVGNDEALFIVVHQVYELWFKLILRELTFARDLLRQDT
T23O_SORC5 WDYIHVEELLALQGGFDDD-EQKVGNDEALFIVVHQIYELWFKLILRELTSARELFRQNP
D0LHK4_HALO1 WDYIKVEELLGLQTGLGDD-EGTLSNDEVMFIVVHQIDELWFKLTLRELASVRALFAQEH
T23O_ANADE GSYLALDELLAAQRPRSE------EHDELLFIVVHQVYELWFKQVVHELTWLQERLHRG-
T23O_HERA2 ASYLKIDELLNLQTPRSHG-P---EHDELLFIVIHQVYELWFKQILHELDYLCDLLRAN-
T23O_BRADU GDYLALDAILGAQHPLSE------AHDEMLFIIQHQTTELWMRLAIHELSAARRAIARD-
Q9RYH4_DEIRA GDYLHLDELRSAHQPITD------AHDEHLFIAIHHVSEVWLSLIVRELQAAMRLLDAG-
T23O_BURPS GDYLSLDPILDAQHPRSP------DHNEMLFIIQHQTSELWMKLALYELRAALASIRDD-
T23O1_RALN1 GDYLALDQILNAQHPRSP------DHNEMLFIVQHQTTELWMKLMLHELRAARDCVRND-
T23O_BORPE GDYLHLDELLGAQHPLSP------EHNEMLFIVQHQTSELWMKLMLHELRAAIAAIQQD-
T23O_PSEAE GDYLKLDKVLDAQFPLSP------DHNEMLFIIQHQTSELWMKLMLHELRAAREHVKSG-
T23O_PSEFL GDYLGLDKVLDAQVPRSQ------QHNEMLFIIQHQASELWMKLLLHELRHARQLIDQG-
T23O_BACAN GEYLQLDSLLSSQKRLSD------HHDEMLFIVIHQASELWMKLILHELNAAIESIKQD-
Q81CK2_BACCR GEYLQLDSLLSSQKRLSD------HHDEMLFIVIHQASELWMKLILHELNAAIEFIKQD-
T23O_CAUVC ARYLALDELLSAQKPLSD------RHDELLFIVIHQTKELWLKEILHEVALALKLIAGG-
T23O_XANCP GGYLRLDQLLSAQQPLSEP-A---HHDEMLFIIQHQTSELWLKLLAHELRAAIVHLQRD-
D7AZD8_NOCDD VDYAGIDTLLSLQKPRTA------EPAEPSFIIATQVMELLFALVRERWEAARDALEAD-
D7BWH7_STRBB AAYARMDTLLSLQHPRTG------AETEPGFIILSQVKELLFKLCHTEFSTARDHLAAD-
Q9X8R3_STRCO EDYVKADVLTHLQHTLSD------DPGEMVFLVTTQVMELWFTVIVHEWETAARALRED-
D2AYJ2_STRRD DDYVGTATLHRLQRTVTD------APEELAFLVTTQVMELYFGLLRSEWQLAQRQLDDD-
B0T9I9_CAUSK IDFHRNDVLHSLQHMRTE------AYDEFPFIVMTQVKELIFRSIHYELANIQQRIRDD-
G1MAF5_AILME GNYLHLEKVLNAQELQSEI-KGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQSGH
H0WPN4_OTOGA GNYLHLEKILHAQELQSEI-KGNKIHDEHLFIVTHQAYELWFKQILWELDSVREIFQSGH
T23O_HUMAN GNYLHLEKVLNAQELQSET-KGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGH
G1R355_NOMLE GNYLHLEKVLNAQELQSET-KGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGH
T23O_BOVIN GNYLQLEKVLNAQELQSEM-KGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGH
T23O_MOUSE GNYLQLEKILNAQELQSEV-KGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGH
T23O_RAT GDYLQLEKILNAQELQSEI-KGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGH
G1PKL2_MYOLU GNYLHLEKILNAQELQSEL-KGNKIHDEHLFIITHQAYELWFKQILWELDSVCEIFQNGH
T23O_XENTR GDYLQLDKVLNAQELQSEK-KGNKIHDEHLFIVTHQAYELWFKQILWELDSVREIFQNGH
T23OA_DANRE GDYLQLDKIVTSQVLQSEL-KGNKIHDEHLFIVTHQAYELWFKQVLWELDSVREIFISGH
T23OB_DANRE GDYLQLDKVLNAQVLQSEQ-KGNKIHDEHLFIVTHQAYELWFKQILWELDSVRDLFIKKH
T23O_AEDAE GEYLMLDKVLSAQRMLSVE-SNKPVHDEHLFIVTHQAYELWFKQIIFELDSIRSLFS-TE
T23O_ANOGA GEYLMLDKVLSAQRMLSVE-GKKPVHDEHLFIVTHQAYELWFKQIIFELDSIRDLFS-TE
T23O_DROME GEYLMLDKLLDAQCMLSEE-DKRPVHDEHLFIITHQAYELWFKQIIFEFDSIRDMLD-AE
T23O_DROPS GEYLMLDKLLDAQCMLSTE-DKRPVHDEHLFIITHQAYELWFKQIIFEFDSIRDMLD-AE
E0VBN6_PEDHC GEYLQLEKILNAQTLLSEQ-HNRTVHDEHLFIITHQAYELWFKQIIWEVDSVRNLFGFSE
E9G9M1_DAPPU GEYLQLDKILDGQRLMSEQLGSETVHDEHLFIVTHQAYELWFKQILYELDSVREMFS-NE
T23O_CAEBR PEYLQLDKILTAQKLKSEA-DGQRVDDEHLFIVIHQAHELWFKQIIFDLDIVRKLLN-NT
T23O_CAEEL SEYLQLDKILTAQRLKSEA-DGQRVDDEHLFIVIHQAHELWFKQIIFDLDNVRKLLN-NT
T23O_DICDI GSYLKLDELLNIQECESVK-VGAPAHEEMLFIIIHQTYELWFKQMIHEIDSIRSIMS-TP
F0ZW87_DICPU GSYLKLNELLGIQNLESVK-AGQPAHEEMLFIIIHQTYELWFKQIIHEIDSIRNIMS-TP
: : : * *: : *: : .
T23O2_RALN1 VPGH-QIALGVRSLRRAIAVFEQANQHFRVMETMTARDFLDFRERLMPASGFQSAQLREI
T23O_SORC5 VPDQ-KLASAARSFRRVVTIFEQAIEHFRVMETLTTRDYLDFRDRLIPASGFQSAQLREI
D0LHK4_HALO1 VREQ-SLSSAVRGIRRAALLFEQTAGHFALMETMTTRDYLAFRDKLSPASGFQSAQMREI
T23O_ANADE -----EGGHALATLKRVLTILKTVVAQVDVIETMTPRQFTAFRSRLEAASGFQSAQFRVL
T23O_HERA2 -----DTGRANQSIRRILTILKTIVAQVDVMETMTPLQFNAFRGSLESASGFQSLQFREI
T23O_BRADU -----EVQPAMKMLARMSRIFEQLNNAWDVLRTMTPSEYTRFRSQLGQSSGFQSRQYRLI
Q9RYH4_DEIRA -----ITDAPLKMLTRVVRAQEQLTAAWDVLKTMTPADYLQFRGAFGQASGFQSQNYRMV
T23O_BURPS -----ALPPAFKMLARVSRVLEQLVQAWNVLATMTPSEYSAMRPYLGASSGFQSYQYREL
T23O1_RALN1 -----DLPPAFKMLARVSRIMDQLVQAWNVLATMTPPEYSAMRPHLGQSSGFQSYQYREI
T23O_BORPE -----RLQPAFKMLARVSKILEQLVSAWDVLATMTPPEYSALRPYLAHSSGFQSYQYRQI
T23O_PSEAE -----KLGPALKMLARVSRIFDQLVHAWAVLATMTPTEYNTIRPYLGQSSGFQSYQYREI
T23O_PSEFL -----QLAGSHRVLARVLRIMEQMVSSWAILATLSPMEFISFRSDLGNASGFQSYQYREI
T23O_BACAN -----KLQPAFKMLARVSKIQSQIIQSWDILATLTPSEYIEFRDSLGQASGFQSYQYRMI
Q81CK2_BACCR -----KLQPAFKMLARVSKIQSQIIQSWDILATLTPSEYIEFRDSLGQASGFQSYQYRMI
T23O_CAUVC -----DVEPAYKALARVSRIQTVMTLSWDILATMTPADYLSFRDDLGTSSGFQSHQFRAL
T23O_XANCP -----EVWQCRKVLARSKQVLRQLTEQWSVLETLTPSEYMGFRDVLGPSSGFQSLQYRYI
D7AZD8_NOCDD -----DVPEALAWLRRARNAQDVLNDSWGLLADMTPTEFNRFRDSFGEASGFQSYGYRKL
D7BWH7_STRBB -----RLDEVLWTLRRARRVQQLLLSCWDALGALTPGEFASFRDALGPASGFQSGMYRRL
Q9X8R3_STRCO -----RTPVATDALKRSVRELEALNASWTPLAGLTPAQFNSYRSALGEGSGFQSAMYRRL
D2AYJ2_STRRD -----DAATATVTIKRTVRHFEALNAAWASLSWLTPAQFNQFRDALGEASGFQSALYRHV
B0T9I9_CAUSK -----DLTGALVLAPRLRRCLELLVKTWDVLSTITTQGFNAFRDQLGTSSGQQSYAYRHV
G1MAF5_AILME VRDERNMLKVVTRMHRVVVILKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLL
H0WPN4_OTOGA VRDERNMLKVVTRMHRVTVILKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLL
T23O_HUMAN VRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLL
G1R355_NOMLE VRDERNMLKIVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLL
T23O_BOVIN VRDERNMLKVITRMHRVVVILKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLL
T23O_MOUSE VRDERNMLKVIARMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLL
T23O_RAT VRDERNMLKVMTRMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLL
G1PKL2_MYOLU VRDERNMLKIVTRMHRVVVILKLLVEQFSVLETMTALDFNDFREYLSPASGFQSLQFRLL
T23O_XENTR VRDERNMLKVVTRIHRISMILKLLVEQFSVLETMTAMDFFDFRDYLSPASGFQSLQFRLL
T23OA_DANRE VRDERNMLKVNTRIHRIVMIFRLLLDQFAVLETMTALDFYDFREYLSPASGFQSLQFRLL
T23OB_DANRE VRDERNMLKVVSRIHRITMIFKLLVDQFAVLETMTALDFFDFREYLSPASGFQSLQFRLL
T23O_AEDAE HMEESRTLEILKRLNRIVMILKLLVDQVPILETMTPLDFMDFRDFLSPASGFQSLQFRLL
T23O_ANOGA HIEESRTLEILKRLNRIVMILKLLVDQVPILETMTPLDFMDFRDYLSPASGFQSLQFRLL
T23O_DROME VIDETKTLEIVKRLNRVVLILKLLVDQVPILETMTPLDFMDFRKYLAPASGFQSLQFRLI
T23O_DROPS VIDETKTLEIVKRLNRVVLILKLLVDQVPILETMTPLDFMDFRKYLAPASGFQSLQFRLI
E0VBN6_PEDHC TVDEGKTLEILKRLNRIVLILKLLVDQVMILETMTPLDFMEFRDYLSPASGFQSLQFRLL
E9G9M1_DAPPU EIEERKMLEVLKRMNRIVLIWKLLRDQVMILETMTPLDFMEFREYLTPSSGFQSLQFRLL
T23O_CAEBR IVDETKTLKIVSGLDRIVKILSLLTEQITLLDTMSPLDFVDFRKYLTPASGFQSLQFRIL
T23O_CAEEL IVDETKTLKIVSGLDRMTKILSLLTEQITLLDTMSPLDFVDFRKYLTPASGFQSLQFRVL
T23O_DICDI PTPERLNGVIVNRLGRITEIQKLLVDQISILETMTSVDFLEFRNLLVPASGFQSVQFRMI
F0ZW87_DICPU PTPERLNGVIVNRLQRVTEIQKLLVDQISILETMTSVDFLEFRNLLVPASGFQSVQFRMI
* : ::. : * : .** ** * :
T23O2_RALN1 EILLGLEDNERIAVCQGGSFKDALKLPNGALSSAAYRVEAREAHGQSLKHCLYAWLSRIP
T23O_SORC5 ELLLGLDDALRIPLGREGSYKEALKTADGAPSAATRRVEARLASGPSLKHFLDEWLSRTP
D0LHK4_HALO1 EILLGLPENERMALGHE-TYMQALRDPDGGETAASLRVQARQRDTPTVRAAIEEWLYRTP
T23O_ANADE EAMLGR--------------RDDRMLAPYPPDGPGYARIAAAMAAPSLFDSLLRYLATQG
T23O_HERA2 EFVLGY--------------KRPAILQHFAA-LPSHERLEQRYQEPSLWDSFLHYLQLNG
T23O_BRADU EYLLGN--------------RNHAMLKPHAHDAEVTKLLEAELATPSLYDEVLRLADRNG
Q9RYH4_DEIRA EFLLGN--------------RNSTLLRPHEHRADLHRPLAAALHAPSVYDLTLRLLAARG
T23O_BURPS EFILGN--------------KNAQMLRPHAHRPAIHAHLEASLQAPSLYDEVIRLLARRG
T23O1_RALN1 EFILGN--------------KNAAMLQPHAHQPEHYAQVKAALETPSLYDEAIRYMARHG
T23O_BORPE EYLLGN--------------KNAAMLQPHAHRADLLAQVRAAFEAPSLYDEALRFLARSG
T23O_PSEAE EFILGN--------------KNATLLKPHAHRAELLAALEQALHTPSLYDEAIRLMAAQG
T23O_PSEFL EFIFGN--------------KNRAMLLPHQHTPQIAKNLEQCLHTPSLYDAIIQQMTRQD
T23O_BACAN EYALGY--------------KTPHALKIYEKDPELHARLHTALHAPSLYNVAIQALVKEG
Q81CK2_BACCR EYALGY--------------KTPHALKIYEKDPELHARLHKALHAPSLYDVAIQALVKEG
T23O_CAUVC EYLLGL--------------KDQSFLKFHTERPEALAMLKSALESPSLYDVAIAQLPRHG
T23O_XANCP EFLLGN--------------KNPQMLQVFAYDPAGQARLREVLEAPSLYEEFLRYLARFG
D7AZD8_NOCDD EFLLGN--------------KSAAMIRPHKAMDGVADDLTALLERPGLYDAALRLLHRRG
D7BWH7_STRBB EFLLGN--------------KNPQLLEPHRNTSRYGEVLAQLYE-PSLYDEAIRHLARRG
Q9X8R3_STRCO EFLLGD--------------KSASMLVPHRGAPRVHAELEKALHEPSLYDEVVRLLARRG
D2AYJ2_STRRD EFLLGN--------------KSEALIRPHRRNPEAYSELAEALARPSLYDSVLAFLARQG
B0T9I9_CAUSK EFILGN--------------KSRRLAAAHANNPDVYPAIAEALNSPSLYDDAIALLHRRG
G1MAF5_AILME ENKIGVLQSLR------VPYNRRHYRDNFKGEDNELLLK--SEQEKTLLQLVEAWLERTP
H0WPN4_OTOGA ENKIGVLQSLR------VPYNRRHYRDNFKGEDNELLLK--SEQEKTLLQLVEAWLERTP
T23O_HUMAN ENKIGVLQNMR------VPYNRRHYRDNFKGEENELLLK--SEQEKTLLELVEAWLERTP
G1R355_NOMLE ENKIGVLQNMR------VPYNRRHYRDNFKGEENELLLK--SEQEKTLLELVEAWLERTP
T23O_BOVIN ENKIGVLQSLR------VPYNRRHYRDNFRGKDNELLLK--SEQERTLLQLVEAWLERTP
T23O_MOUSE ENKIGVLQSLR------VPYNRKHYRDNFGGDYNELLLK--SEQEQTLLQLVEAWLERTP
T23O_RAT ENKIGVLQSLR------VPYNRKHYRDNFEGDYNELLLK--SEQEQTLLQLVEAWLERTP
G1PKL2_MYOLU ENKLGIFQSLR------VPYNRRHYRDNFKGEENELLLK--SEQDKTLLQLVEAWLERTP
T23O_XENTR ENKIGVPEILR------VPYNRRHYRDNFKGETNELLLK--SEQELTLLGLVEAWLERTP
T23OA_DANRE ENKIGVPHNQR------VPYNRRHYRDNFRDQESELLLH--SEQEPTLLQLVEQWLERTP
T23OB_DANRE EQKIGVADHLR------VPYNRRHYRDNFHGEESETLLS--SEQEPTLLQLVEQWLERTP
T23O_AEDAE ENKLGVKTEHR------VKYNQ-KYSEVFASDPCAIERLSITESEPSLADLVQKWLERTP
T23O_ANOGA ENKLGVKSEHR------VKYNQ-KYTEVFASDPGAIERIGTTETEPSLADLVQKWLERTP
T23O_DROME ENKLGVLTEQR------VRYNQ-KYSDVFS-DEEARNSIRNSEKDPSLLELVQRWLERTP
T23O_DROPS ENKLGVLTEQR------VRYNQ-KYSDVFGGDEQALSAIRSSEYEPSLLELVQRWLERTP
E0VBN6_PEDHC ENKLGVKLDHR------MRYSQ-RYSKVFDRDPEAVAAIKKSETEPSLGKLVESWLERTP
E9G9M1_DAPPU ENKLGIRQEHR------VRYNQSNYIKVFGNDKAAMIELERSESEPSLCELVQKWLERTP
T23O_CAEBR ENKLGVKQERR------IKYNAQHYKNVFNDDDLKALNT--TEDEKSLLTLIESWLERTP
T23O_CAEEL ENKLGVRQERR------IKYNAQHYKNVFNDTDLKTLNV--TEEEKSLLTLIESWLERTP
T23O_DICDI ENKLGILPNTR------VQYQQHHYHSFFNEKDRKALQA--TENEVSLLQLVIQWLERNP
F0ZW87_DICPU ENKLGILPQTR------VQYQQHHYSSFFNEDDRKKLSD--TENETSLLQLVIQWLERNP
* :* :
T23O2_RALN1 IDGSN-----EPAAVKRFLRDYIGSVRAESQRRLQTAIDRQLAPAEVERLRARYQADDVG
T23O_SORC5 IDGSS-----EPEGVVGFLRSYTRSMRQENERRVQMAIDKALTPPDVERLRARYEAESAA
D0LHK4_HALO1 IDGFTPDSEGDAEAVAAFIDSYLEAHRRELAGIQARAVASALTEADRTRLGERYERELAS
T23O_ANADE FETPV-------------------------------------------------------
T23O_HERA2 YAIPS-------------------------------------------------------
T23O_BRADU LTMPA-------------------------------------------------------
Q9RYH4_DEIRA LPVPA-------------------------------------------------------
T23O_BURPS FPIAP-------------------------------------------------------
T23O1_RALN1 FAFDA-------------------------------------------------------
T23O_BORPE LAVPA-------------------------------------------------------
T23O_PSEAE LPVSQ-------------------------------------------------------
T23O_PSEFL LPICA-------------------------------------------------------
T23O_BACAN FPIHK-------------------------------------------------------
Q81CK2_BACCR FPIHK-------------------------------------------------------
T23O_CAUVC LTVPD-------------------------------------------------------
T23O_XANCP HAIPQ-------------------------------------------------------
D7AZD8_NOCDD LPVPE-------------------------------------------------------
D7BWH7_STRBB LDIPP-------------------------------------------------------
Q9X8R3_STRCO YDIPD-------------------------------------------------------
D2AYJ2_STRRD YAIPR-------------------------------------------------------
B0T9I9_CAUSK FVIPQ-------------------------------------------------------
G1MAF5_AILME GLEPHG--------------FNFWGKFENNIVKGLEEEFIKIQAKE--ESEEKEEQMAEF
H0WPN4_OTOGA GLEPHG--------------FNFWGKFEKNIVKGLEEDFIRIQARE--ESEEKEEQMAEF
T23O_HUMAN GLEPHG--------------FNFWGKLEKNITRGLEEEFIRIQAKE--ESEEKEEQVAEF
G1R355_NOMLE GLEPHG--------------FNFWGKLEKSITRGLEEEFIRIQAKE--ESEEKEEQVAEF
T23O_BOVIN GLEPHG--------------FNFWGKLEKNIVKGLEEEFTKIQAKE--ESEEKEEQMAEF
T23O_MOUSE GLEPNG--------------FNFWGKFEKNILKGLEEEFLRIQAKT--DSEEKEEQMAEF
T23O_RAT GLEPHG--------------FNFWGKFEKNILKGLEEEFLKIQAKK--DSEEKEEQMAEF
G1PKL2_MYOLU GLEKHG--------------FNFWEKLEKNIVKGLEEEFSMIQAKN--ESEEKEEQMAEF
T23O_XENTR GLEEEG--------------FHFWGKLEANIFRGLEEELQTVKTKP--DSEEKEEQLAEL
T23OA_DANRE GLEEDG--------------FNFWGKLEKNIFEGLRREKEHIEQKP--ASERKEEMLAEL
T23OB_DANRE GLEKDG--------------FNFWGKLQANIEEGLKREKHQVEKME--DTEVKQELLEDL
T23O_AEDAE GLETNG--------------FNFWGKFEESVEQLLADQEASAMEEE--HENVKNYRLMDI
T23O_ANOGA GLEQDG--------------FNFWGKFQESVEQLLAEQEASAMSEE--HENVREYRLMDI
T23O_DROME GLEESG--------------FNFWAKFQESVDRFLEAQVQSAMEEP--VEKAKNYRLMDI
T23O_DROPS GLEESG--------------FNFWKKFQQSVDQFLAAQVEIAMEEP--VEQAKNYRLMDI
E0VBN6_PEDHC GLETEG--------------FNFWKKYKDAVDRMLMNQSEAADKIT--NEDEKKRSQSDV
E9G9M1_DAPPU GLDEEHP-------------SNFWTQYQETVEALIRDQQKEAEVTT--DESLKVHLLNEC
T23O_CAEBR GLKSTSED------------EGFWSKYESSVNKYLSDLAKQAEDPSN-TEEIKKQLRAEY
T23O_CAEEL GLKSTSED------------EGFWIKYEKSVNKYLADLAKQAADPSN-TEEIAKQLTAEY
T23O_DICDI FLYYKG--------------YDFWSSYKSAVDQILENDLQRIQANNDLSQDMKDQSTKEA
F0ZW87_DICPU FLYNKG--------------YDFWSSYKSAVDKILENDLARIQSNTELTQDMKDQSTKEA
T23O2_RALN1 AETFLLAEEDPQAD-------AMTREKRRAVRAAMLFVESYRELPQLAWPRELLESILEL
T23O_SORC5 AEAFLLAEDDPAAD-------AATREKRRAVRAAIVFIESYRELPRLAWPREVLDRILEM
D0LHK4_HALO1 ARAWLEGRDVSAAHDDSEGTIERTRARRSRIRAALVFIESYRELPLLAWPREVLDAIVAL
T23O_ANADE --------VPEPRP--------AGWRQ-PSEAVQRVLLEVYRADG---EAALVCERFVDL
T23O_HERA2 --------EQIGRD--------VTQSLVASPAIQTILITVYRQNP---LVSNLCERLIDL
T23O_BRADU --------AVLSRD--------VRETHSFNEGVLQAWRVVYEAPETHWMLYELAEKLVDF
Q9RYH4_DEIRA --------EVLQRD--------YAQPYQTNEAVLASWLSVYCDTETYWDLYELAEKLVDV
T23O_BURPS --------ERLDAD--------WTQPTRHDRTVEAAWLAVYREPNAHWELYEMAEELVDL
T23O1_RALN1 --------DCIERD--------WSRPVTYNASVEAAWLEVYRDPTHHWELYELAEKFVDL
T23O_BORPE --------GALQRD--------WTQPYRADDQVEQAWLTVYRQSERYWNQYQLGEKLTDL
T23O_PSEAE --------ERLARD--------AAAGTCYEASVEAAWRQVYQAPERYWDLYQLAEKLIDL
T23O_PSEFL --------LRLDAD--------PSEPTRSDASVEAAWVQVYRQPERYWDLYQLGEKLMDI
T23O_BACAN --------DVLNRD--------ITQPYEEDATVEAAWLEVYADVKKYWNLYQLAEKLIDI
Q81CK2_BACCR --------DVLNRD--------ITQPYEEDATVEAAWLEVYADVKKYWNLYQLAEKLIDI
T23O_CAUVC --------AALHRD--------FSQTYVPSPEVEAAWLEVYRDPKRYWELYQLAEKLVDL
T23O_XANCP --------QYQARD--------WTAAHVADDTLRPVFERIYENTDRYWREYSLCEDLVDV
D7AZD8_NOCDD --------DRVERD--------WTLPYEASPAVEEAWKAVYAHDVPGNELFLLAEALLDV
D7BWH7_STRBB --------VHADRD--------FSLPYQPDEKVAAAWRLIYEQPGRHPGLFLLAEALMDT
Q9X8R3_STRCO --------AVLQRD--------LTRKYEAAPEVEAAWTAVYSGD-QNGELARLGEALTDV
D2AYJ2_STRRD --------EAVERD--------YAADYEPRSDVEAVWAEVYGG-----PLAPLAEALTDL
B0T9I9_CAUSK --------DRLERD--------WAEDYAPSPAVAAAWLAVYDTPTPENDLYQLGEMLIEI
G1MAF5_AILME QKQKEVLLSLFDEKRHEHLYSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDI
H0WPN4_OTOGA QKQKEVLLSLFDEKRHDHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDI
T23O_HUMAN QKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDI
G1R355_NOMLE QKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDI
T23O_BOVIN QKQKEVLLSLFDEKRHEHLLSKGERRLSYKALQGALMIYFYREEPRFQVPFQLLTFLMDV
T23O_MOUSE RKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDI
T23O_RAT RKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDI
G1PKL2_MYOLU HKQKEVLLLLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVAFQLLTSLMEI
T23O_XENTR QKQKELFGALFDERRHEHLLSKGERRLSYKALKGALMIYFYREEPRFQVPFQLLTSLMDI
T23OA_DANRE IKQRDIFLSLFDEKRHDHLVSTGQRRLSYKALQGALMIYFYREEPRFQVPFQLLTSLMDI
T23OB_DANRE NKQMETFTALFDSKRHEHLLSKGERRLSYKALQGALMINFYREEPRFQVPFQLLTALMEI
T23O_AEDAE EKRREVYKSIFDASVHDALVARGDRRFTHRALQGAIMITFYRDEPRFSQPHQLLMLLMDI
T23O_ANOGA DKRREVYKSIFDAQVHDALVARGERRFTHKALQGAIMITFYRDEPRFSQPHQLLMLLMDI
T23O_DROME EKRREVYRSIFDPAVHDALVRRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDI
T23O_DROPS EKRREVYHSIFDPAVHEALVKRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDI
E0VBN6_PEDHC ERKKEMFASVFDKQIHDAFVLKGERRFSHKALQGAIMITFYRDEPRFSQPHLLLTLLMDI
E9G9M1_DAPPU QKKKELFDSIFDVDIHNALVARGERRFSHKALQGAIMITFYRDEPRFNQPHQLLSILMDI
T23O_CAEBR SKTSDAFQSILDPRQHEQHIRNGNRLLSHDATKGAMMIYFYRDMPRFSQPYQILTFLMDI
T23O_CAEEL HKTADAFQSILDPRQHEQHIRNGNRLLSHDATKGAMMIYFYRDMPRFSQPYQILTFLMDI
T23O_DICDI KKNMESFSTLFDEVAYNERLEKGEVRLSYKALQSAILIYLYKDEPIFHTPFLILNLLTEI
F0ZW87_DICPU QKNMESFSTLFDEKTYNSKLEKGEVRLSYKALQSAILIFLYKDEPIFHTPFLILNLLTEI
* : :
T23O2_RALN1 EQSMLIWRQRHARMVERIIGR-RVGTGGSSGVDYLD-QTALRYRVFTDLWTVRSLLLRKS
T23O_SORC5 EQAMLIWRQRHARMVERVIGR-RTGTGGSAGVDYLD-QTALRYRVFGDLWTVRSLLLRKP
D0LHK4_HALO1 EQAFTIFRQRHARMVERVIGR-RTGTGGSAGVDYLD-RTALTYRVFRDIWATRTVLLRES
T23O_ANADE DEGVQEWRYRHVKMVERTIGD-KPGTGGSAGARYL--RSTLFTPAFPDLWAVRGAL----
T23O_HERA2 DEGFQEWRYRHVKMVERTIGM-KQGTGGSSGAAYL--ASTI-KPFFPDLWAIRADL----
T23O_BRADU EDYFRRWRFNHVTTVERVIGF-KRGTGGTGGVSYL--KRMLEVELFPELWRVRTIL----
Q9RYH4_DEIRA EDNFRRWRFNHLTTVERTIGF-KRGSGGTSGVGYL--RGALDVVLFPELWDVRTQL----
T23O_BURPS EDAFRQWRFRHVTTVERIIGF-KQGTGGTSGAPYL--RKMLDVVLFPELWHVRTTL----
T23O1_RALN1 EDAFRQWRFRHVTTVERVIGF-KRGTGGTEGVNYL--RKMLDVVLFPELWKLRTDL----
T23O_BORPE EDAFRLWRFRHVTTVERIIGF-KRGTGGTSGVTYL--RKMLEVVLFPEIWKLRTDL----
T23O_PSEAE EDSFRQWRFRHVTTVERIIGF-KPGTGGTEGVGYL--RSMLDTILFPELWRLRSNL----
T23O_PSEFL EDAFRQWRFRHVTVVERVIGF-KKGTGGTEGVEYL--RKMLGTVLFPELWSLRSSL----
T23O_BACAN EDWLQQWRFRHMKTVERIIGH-KMGTGGSSGVSYL--KRVLDQRFFPELWNVRTKL----
Q81CK2_BACCR EDWLQQWRFRHMKTVERIIGH-KMGTGGSSGVSYL--KRVLDQQFFPELWNVRTKL----
T23O_CAUVC DDALVTWRHKHVLTVERIIGG-RPGTGGTDGVGYL--ASTLRRRAFPELWSLRTKL----
T23O_XANCP ETQFQLWRFRHMRTVMRVIGF-KRGTGGSSGVGFL--QQALALTFFPELFDVRTSVGVDN
D7AZD8_NOCDD AERVTRWRQRHLVAVKRTLGG-RPGSGGSNGLRWL--ARNAEQDVFPELWSLRSTV----
D7BWH7_STRBB ADLFARWRYTHLVTVQRLLGN-RPGTGGTEGSPWL--AAIAEHRFFPELWSIRSTGE---
Q9X8R3_STRCO AELVWRWRNDHLVATRRAMGS-KTGTGGSAGVAWL--EKRARNNVFPELWTARSYV----
D2AYJ2_STRRD ATQFSDWRYRHLMAVRRSMGA-KPGSGGSSGLSWL--ERSMRREIFPELWTARTLM----
B0T9I9_CAUSK DDLFSQFRWRHFVSVQRILGL-KPGTGGSAGVGWL--RAAVDLRFFPELWSIRTEMGA--
G1MAF5_AILME DTLMTKWRYNHVCMVHRMLGS-KAGTGGSSGYQYLRSTVSDRYKVFVDLFNLSTYLVPRH
H0WPN4_OTOGA DTLMTKWRYNHVCMVHRMLGS-KAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYMVPRH
T23O_HUMAN DSLMTKWRYNHVCMVHRMLGS-KAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLIPRH
G1R355_NOMLE DSLMTKWRYNHVCMVHRMLGS-KAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLIPRH
T23O_BOVIN DSLMTKWRYNHVCLVHRMLGS-KAGTGGSSGYQYLRSTVSDRYKVFVDLFNLSTYLVPRH
T23O_MOUSE DTLMTKWRYNHVCMVHRMLGT-KAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLVPRH
T23O_RAT DTLMTKWRYNHVCMVHRMLGS-KAGTGGSSGYYYLRSTVSDRYKVFVDLFNLSSYLVPRH
G1PKL2_MYOLU DTLMTKWRYNHVCLVHRMLGS-KAGTGGSSGYQYLRSTVSDRYKVFVDLFNLSTFLIPRH
T23O_XENTR DTLMTKWRYNHVCMVHRMIGS-KAGTGGSSGYQYLRSTVSDRYKVFVDLFNLSTYLVPRH
T23OA_DANRE DTLMTKWRYNHVCMVHRMIGS-KDGTGGSSGYQYLRSTVSDRYKVFVDLFNLATFLIPRD
T23OB_DANRE DTLMTKWRYNHVCMVHRMIGS-KAGTGGSSGYHYLRSTVSDRYKVFVDLFNLATFLVPRS
T23O_AEDAE DSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFIDLFNLSTFLIPRG
T23O_ANOGA DSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPRQ
T23O_DROME DSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPRE
T23O_DROPS DSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPRE
E0VBN6_PEDHC DSLITKWRYNHVIMVQRMIGSLQLGTGGSSGYQYLKSTLSDRYKVFLDLFNLSTFLIPRN
E9G9M1_DAPPU DSLITKWRYNHVMLVQRMIGSQRIGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFILPRK
T23O_CAEBR DSLFTKWRYNHVLLVQRMLGA-KQGTGGSSGYMYLRSTVSDRYKVFLDLFNLSTWLIPRE
T23O_CAEEL DSLFTKWRYNHVLLVQRMLGA-KQGTGGSSGYMYLRSTVSDRYKVFLDLFNLSTWLIPRE
T23O_DICDI DELLTMWRFRHTMMVQRIIGA-KIGTGGSSGYHYLRTTVGDRYKIFLDLFNISSYLIPKN
F0ZW87_DICPU DEQLTLWRFRHTMMVQRIIGA-KIGTGGSSGYHYLRTTVGDRYKIFLDLFNISSYLIPKN
. :* * . * :* : *:**: * :* * :::
T23O2_RALN1 SVPPIRQGASYAFAEEALV--------------------------------
T23O_SORC5 SVPEIEHASDYGFRVEDSP--------------------------------
D0LHK4_HALO1 ALPPLVHADYYGFAGSGA---------------------------------
T23O_ANADE ---------------------------------------------------
T23O_HERA2 ---------------------------------------------------
T23O_BRADU ---------------------------------------------------
Q9RYH4_DEIRA ---------------------------------------------------
T23O_BURPS ---------------------------------------------------
T23O1_RALN1 ---------------------------------------------------
T23O_BORPE ---------------------------------------------------
T23O_PSEAE ---------------------------------------------------
T23O_PSEFL ---------------------------------------------------
T23O_BACAN ---------------------------------------------------
Q81CK2_BACCR ---------------------------------------------------
T23O_CAUVC ---------------------------------------------------
T23O_XANCP RPPQGSADAGKR---------------------------------------
D7AZD8_NOCDD ---------------------------------------------------
D7BWH7_STRBB ---------------------------------------------------
Q9X8R3_STRCO ---------------------------------------------------
D2AYJ2_STRRD ---------------------------------------------------
B0T9I9_CAUSK ---------------------------------------------------
G1MAF5_AILME WIPKMNPIIHKFLYTAEYCDSSYFS--SDESD-------------------
H0WPN4_OTOGA WLPKMNPTIHKFLYTAEYCDSSYFS--SDDSD-------------------
T23O_HUMAN WIPKMNPTIHKFLYTAEYCDSSYFS--SDESD-------------------
G1R355_NOMLE WIPKMNPTIHKFLYTAEYCDSSYFS--SDESD-------------------
T23O_BOVIN WIPKMNPVIHKFLYTAEYCDSSYFS--SDESD-------------------
T23O_MOUSE WVPKMNPIIHKFLYTAEYSDSSYFS--SDESD-------------------
T23O_RAT WIPKMNPIIHKFLYTAEYSDSSYFS--SDESD-------------------
G1PKL2_MYOLU WIPKMNPITRKFLYTTEYCDSSYFS--SEESD-------------------
T23O_XENTR WVPRLNPSIHKFLYTAECCDSSYFS--SDDSD-------------------
T23OA_DANRE WVPKLDPSEHTFLYMAECCDSSYCS-SSDDSD-------------------
T23OB_DANRE WVPKLNPNIHKFPYTAECYDSSYNSCSSEDSD-------------------
T23O_AEDAE SIPPLTCEMQKALNLAWGSPVHQAKQINYAAK-------------------
T23O_ANOGA SIPPLTNEMQKALNLAWGSPAHFARNGSLH---------------------
T23O_DROME AIPPLDETIRKKLINKSV---------------------------------
T23O_DROPS AIPPLDETIRKKLVHKSV---------------------------------
E0VBN6_PEDHC YIPPLNKDMKFKLGNPQS---------------------------------
E9G9M1_DAPPU YIPPLSRHMKTRLSIREEPHTQNRPSNSEDDNKSQSGSSTSGLETSGELSL
T23O_CAEBR YIPMLSPRMVKTLSEHSNLSHSQSS----ESE-------------------
T23O_CAEEL YIPMLSPRMVKTLSEHSNLSHSQSS----ESD-------------------
T23O_DICDI TLPQLPKVVKEQMDFAWSIL-------------------------------
F0ZW87_DICPU TLPQLPSVVKEQMDFAWSTL-------------------------------