CLUSTAL format seed alignment for MF_02044
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- An 'X' at the beginning or at the end of a sequence indicates that
the protein is fused with another domain respectively at its N- or
C-terminus.
Sequences that are concerned have a '_P' (for partial) suffix added
to their ID.
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MRE11_PYRHO ----------MKFAHLADVHLGYEQFNKPQRAEEFANTFKKALEMCVKESVDFIIIAGDL
MRE11_PYRAB --------MGIKFAHLADVHLGYEQFNRSQRAEEFAKAFEDAIKICVDEKVDFIVIAGDL
MRE11_PYRFU ----------MKFAHLADIHLGYEQFHKPQREEEFAEAFKNALEIAVQENVDFILIAGDL
Q5JHP8_THEKO ----------MKFAHIADVHLGFEQYRLPYRADEFAEAFRRAIEIAVEEKVDFILIAGDL
MRE11_ARCFU ----------MKFAHIADVHLGYEQYNQPWRAEDFAKAFKVIAEKAVESNADFVVIAGDL
MRE11_HALVD ---------MTRVIHTGDTHLGYQQYHSPERRQDFLDAFERVVADALDGDVDAVVHAGDL
E4NQX8_HALBP ---------MTRVIHTGDTHIGYQQYHSPERRRDFLDAFEQVVADAIADDVDAVVHAGDL
D8J6A3_HALJB ---------MTRVIHTGDTHIGYRQYHSAERRADFLAAFERVAADAIEEGVDAVVHAGDL
L0JP08_NATP1 ---------MTRVIHTGDTHIGYQQYNSPERRRDFLEAFRSVVEDAVADDVDAVIHAGDL
MRE11_HALSA ---------MARVIHTGDTHLGYQQYHAPQRRQDFLDAFDAVITDAIDEGVDAVVHAGDL
Q18JH8_HALWD ---------MTRVIHTGDTHIGYQQYHSQIRREDFLNAFNQVITDACDADVDAVIHAGDL
Q3ISN6_NATPD ---------MTRVLHTGDTHIGYRQYHTPERREDFLSAFRQVADDAVEMDVDAVVHAGDL
MRE11_METAC ------MDREIRILHTADTHLGYRQYHSEVRRQDFFKAFETVIQDAVDMQVDAVVHAGDL
MRE11_SULTO -------MSKTQILHISDTHLGKRQYNLDFREQDVYDTFSQLIDIAIKEHVDGIIHTGDL
MRE11_SULAC ----------MQLLHISDTHLGKRQYNLESREKDVYDTFTQLIDIAINEHVKAVIHTGDL
MRE11_SACS2 ---------MVQILHISDTHLGKRQYSLVEREKDIYDIFSQLVDIAIKEHVDVIIHSGDL
MRE11_METJA ----------MMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDL
MRE11_METMP ----------MQFVHMADNHLGYRQYNLDERENDIYESFLECIDKIIEIRPDFVIHSGDL
MRE11_THEAC -------------MHFSDTHIGYRSLTLDEREQDFYDAFHEAIDIALENSVDFVIHTGDL
MRE11_THEVO ---------MVRFLHMSDTHIGAKSLTIEEREQDYYDTFQEAVEIAIDEKVDFIIHSGDL
MRE11_METTH_P --------XMYRFAHLSDCHLGAQKH--PDLRELEFEAFRMALDDALQKDVDFMIIAGDL
E3GXV9_METFV -------MITYKFAHIADAHIGSHRH--PTLKEMEIKAFENAIDEALKSKVDFIIICGDL
A2BM15_HYPBU MTEADYSVEHLHLLHVSDTHLGYRQYGIIEREMDFYQVFEEVIDIAIREHVDAVIHTGDL
B1L7G0_KORCO ----------MRLVHLSDSHLGKAQFNLAEREEDFYSSFSRAIDIAISEKPDLLIYTGDL
A8A960_IGNH4 ----------MLIVHAADVHLGKRQYGLKEREEDFYKAFEDLVEATIREKADALVIAGDL
MRE11_AERPE ---------MPKVLHVADVHLGARPYGLEERRDDIFRSFEFVVETALKDRPDAVLIAGDL
MRE11_METKA ----------MRMAHVADVHLGHALMNLRSREEAVMETFERLMEEVRECSVDVLVIAGDL
D5U1T5_THEAM ----------MLVAHFADTHLGRILYGIRETEEQIINHFEQAVDQALAEHVDAFIFAGDF
* .* *:* * . .: **:
MRE11_PYRHO FNSSRP--SPGTIKTAIKLLQIPKENNIPVFAIEGNHDRTQRGPSV---LHLLEDLGLLY
MRE11_PYRAB FNSSRP--SPGTIKTAVKILQIPRDNNIPVFAIEGNHDRTQRGPSI---LHLLEDLGLLY
MRE11_PYRFU FHSSRP--SPGTLKKAIALLQIPKEHSIPVFAIEGNHDRTQRGPSV---LNLLEDFGLVY
Q5JHP8_THEKO FHSSRP--SPETLKQAMEILSLPKEKGIPVFGIEGNHDRTQRRVSA---YHLLEKLGLLY
MRE11_ARCFU FHRSLP--SPRTIKEAVETLWMFRKENIPVFAVEGNHDKTSRDISA---YHLLESLGLLN
MRE11_HALVD YHDRRP--ELPDLLGTLAALRRLDDAGIPFLAIVGNHESTR----------GGQWLDLFE
E4NQX8_HALBP FHDRRP--ELRDLLGTISILRQLDDAEIPFLAVVGNHESTR----------GGQWLDLFE
D8J6A3_HALJB FHDRRP--DIGDLLGTLDVLRDLEDADVPFLAIVGNHEGTR----------EGQWLDLFS
L0JP08_NATP1 FHDRRP--SLVDLQGTVDILRTLSAAEIPFLAVVGNHESKR----------DAQWLDLFA
MRE11_HALSA YHDRQP--GLRDILDTIALLRPLQDADIPFLAVVGNHEGTR----------DAQWLDLFE
Q18JH8_HALWD FHDRRP--SLTDLLGTIDILRDLREADIPFLAVVGNHESTR----------HGQWLDLFE
Q3ISN6_NATPD FHDRRP--GLVDLLGTVDILETLDSAGIPFLAIVGNHETKR----------DAQWLDLFE
MRE11_METAC FDSRNP--TLEDLLETMNILSRLKAVDIPFFGIVGNHESKQ----------NTQWLDLFE
MRE11_SULTO FDINDP--PNKAEIVAIRELKRLKEAGIPFIVIAGDHDSPKKFTA----IYPQKILEEFD
MRE11_SULAC FDVNNP--PNRAKLHAIKELKRLKDHNIPFICIAGDHDSPKRKEE----IYPQRILEEFN
MRE11_SACS2 FDVSSP--TTNALVMAIKILKRLKDVNIPFLSIPGDHDTPKRKGY----LIPHNILSELD
MRE11_METJA FNDLRP--PVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGE----ESPLALLKDYV
MRE11_METMP FESPQP--PVNAIRCAMEGLLKLKEKNIPIYLIHGNHDIPKSQQK----GKPFGLLKKIL
MRE11_THEAC FDTWVP--GNRAIREFRNAVMKLNARNIPIFVIFGDHDRPRRNGEP---AAGIFDFMGVH
MRE11_THEVO FDTWIP--GNRSMKVFRDAMMKLNDRQIPVFYVFGDHDRPRRNSES---AAGIFDFLGLH
MRE11_METTH_P FHSNIP--NMETVKRATLELRRVREAGVPIYVNYGSHDYSP---------SSTSMIDILE
E3GXV9_METFV FHSNIP--NMEAAKRTTKKLKDVRDKEIPIYVIYGSHDYSP---------TNTSMIDILE
A2BM15_HYPBU FDSTRP--PAQAIRAAIRALKKLRGHGIPFIVLAGDHDTPKRANLSP--LTELDEVGLAY
B1L7G0_KORCO FDSYRP--HPRAFVRAFESLMKLAERGIPIAIIEGNHELGPDVVRKQITSPIANMETLFN
A8A960_IGNH4 FDTPVPDSTMKPFKVAVEGVRRLRENGIEVIMVAGDHDIPKVRGYP-----AIAYLSELT
MRE11_AERPE FDKPKL--PLRDVKQAVELVRALTDAGIPVLAAHGEHDTPSVRDETLLSLMEASLDGFKA
MRE11_METKA FEHARP--KTEALYLAVEKLSELKEDGVEIVATAGNHEIRRRKGAVS-PISVLERMGLVR
D5U1T5_THEAM LDERKP--PIRVLKKAIEIVEKITGKGVAVFMVPGEHDRWTRGDDS-----PQALFRNAY
. . : . *.*:
MRE11_PYRHO VIGLRQERVENEYLTSERVGNY-WLVKGVY----DNLEIHGMKYMSSAWFEANLNFFKGI
MRE11_PYRAB VLGVRDEKVENEYLTSEKTKAG-WLVKGMY----KDVEIHGMKYMSAAWFEGNIELFKSM
MRE11_PYRFU VIGMRKEKVENEYLTSERLGNGEYLVKGVY----KDLEIHGMKYMSSAWFEANKEILKRL
Q5JHP8_THEKO LIGLREEKVESEHQTSEKTERG-WLVKGVFEKGNKSVEIHGMKYMSAAWLEKNPP--KEI
MRE11_ARCFU VLGLRRNPVRGENVESLRIQNV-YLVKGVV----DDVEILGDRHRSKWQLEKVLPLLKPQ
MRE11_HALVD RLGLATRLGRDP-HVVGGVAFY---------------GLDHVPRS---RRDELDYQFDPV
E4NQX8_HALBP NLGLAERLGDDP-HVVGDTAFY---------------GLDHVPKA---RRDDLAYDFEPH
D8J6A3_HALJB RMGLATRLDSEG-VTVGETTFY---------------GLDHVPVS---RREELEYDFALP
L0JP08_NATP1 DLGLATRLGAEP-VVVDDVAVY---------------GLDFVPRS---RREDLEYEFDPV
MRE11_HALSA TLGLAERLDDSP-RVVADTAFY---------------GLDYVPQS---KRDDHDYTVADH
Q18JH8_HALWD RLGLAERLDNSPRYINDNLALY---------------GLDHVPPS---RREELAYEFNPH
Q3ISN6_NATPD TMGLATRLGDEP-VPVGETAFY---------------GLDFVPRN---QRDDLEYEFATH
MRE11_METAC EMGLAERLGKTP-KLVGNTTIY---------------GIDSVPKSKIPLYDYSGFELPDS
MRE11_SULTO LIKFLSKPDTPYKL--GEITIY---------------GISHVPNVAKERLKELLSRLKPE
MRE11_SULAC LIKILQKIDNRVKL--ENVEVY---------------GISHISNVSVNDLKEQLSKVKPE
MRE11_SACS2 LIKILNY-EKPYII--KGIEVY---------------GIPHIPTVSKSILVSALSALRPK
MRE11_METJA K---ILDGKDVINVNGEEIFIC---------------GTYYHKKSKREEMLDKLKNFESE
MRE11_METMP GNSLLTFGKNKSHVFNNEVFIG---------------GIEYVSQNKIPKTYEDLEKINSD
MRE11_THEAC VLGWDAYEYAVRKFDGEDVLIG---------------GISNMKGYMKTRLKDEYKRSENI
MRE11_THEVO ILGRDEFAGIEREFSGMKVFIG---------------GISNMKGYLRNQLKEEYKKAESA
MRE11_METTH_P SAGVIDKVVRPIPGKKLGLEFT--------VDEKTGAKITGLSGRSRTLEAEYFMKLDRE
E3GXV9_METFV SAGLITKVFHAKACGKIKLEF---------IEDNTGAKICGINARQRSIEKEYFRLLDME
A2BM15_HYPBU TIGAIGDKPTTIQIDTRHGRLL---------------VSGIRSQKGLHARKHLLDAFKQL
B1L7G0_KORCO RLGYGKLFMRLNAKVERIGDLV---------------VAGLPYKSLGKDVPAMISNLEGK
A8A960_IGNH4 GAKLLRGELGAKGYELKGFTFY---------------GDDAVTPSKRGPLERLRAVKPKK
MRE11_AERPE PLYRSGMRPGDFVVDLGSLKVA-------------VVPFFKVPLEERRRLTLRFLREFDQ
MRE11_METKA HLYYSERRPERHRYTATFDGVR--------------VTFHGLQYLPKNSFVERAKVIRAK
D5U1T5_THEAM TPGRNKYFTKRISKNGREYVFT---------------GLNYIYVRSSDEARQALHQQVME
MRE11_PYRHO FR---PDEDAILVLHQGIRDITEKVFPSYS------AELKLSDLPRGYLYYALGHVHKRF
MRE11_PYRAB FR---PEGDAILVLHQGVREITENNYPNYS------SELSLSDLPKGYLYYALGHIHKRF
MRE11_PYRFU FR---PTDNAILMLHQGVREVSEARGEDY-------FEIGLGDLPEGYLYYALGHIHKRY
Q5JHP8_THEKO FR---PEGDSILMLHQGVRELVEEMMGKLPESQRDYYELKLGDLPKGYLYYALGHIHRAF
MRE11_ARCFU S------DKSVLVLHQAVKEVVDIDLDMAY-------ELTINDLPEAS-YYAFGHIHLPK
MRE11_HALVD -----DADRAVLVAHGLFTP----FAHADW-----ETETVLAESNVDFDAVLLGDNHVPD
E4NQX8_HALBP -----DAAHAALVGHGLFTP----FAHADW-----ETETVLGESNVAFDAFLIGDNHAPG
D8J6A3_HALJB -----ETDHAALVAHGLFEP----FGYADW-----DTEELLDSATVEFDAMLLGDNHHPD
L0JP08_NATP1 PA---EADHATLVSHGLFEP----FAHADW-----DTDTVLAASTVDFDALLVGDNHKPD
MRE11_HALSA -----DADHAALVSHGLFTP----FPYANW-----DLDAVLADATVEFDAVLLGDNHTPD
Q18JH8_HALWD -----EATHAALVSHGLFTP----FAHADW-----ETETVLTTASVDFDALLLGDNHAPG
Q3ISN6_NATPD -----DCEHAALVSHGLFEPLVPDYGNVEW-----DIEAVLEASNIDFDAVLLGDEHAAT
MRE11_METAC LP---ENCKKLLVMHQIVQP----FPYADW-----DCAEVLENLPFKVDAILLGDYHKYE
MRE11_SULTO NK------KSILLLHQGLKE----VLPYEG-----AWQIQIDDLPKAFSYYALGHFHTRR
MRE11_SULAC TR------KSILMLHQGIRT----YLPYQG-----AWQIELSDLPKGFSLYAVGHLHSRR
MRE11_SACS2 SS------RSILLLHQGVKQ----ILPYDG-----SWQMELGSLPKGFGYYALGHIHTRW
MRE11_METJA AK---NYKKKILMLHQGINP----YIPLD-------YELEHFDLPK-FSYYALGHIHKRI
MRE11_METMP SK---NYKKKILLFHQSVNP----FIPQS-------FEMQVTDFPDDFNYIAGGHIHQRA
MRE11_THEAC EE---GYRNRILMSHQAIDP----FFVPD------QCEAKMDDLPMNFSYIAMGHLHDFM
MRE11_THEVO ST---GYKNSILISHQALDP----IFIPE------QCEAKVNDLPMNYSYIAMGHLHDFV
MRE11_METTH_P ALEA-EDGFRIFLFHSAITQFKPVDLADME-------SVDLNLFPRGFEYYAGGHVHRKG
E3GXV9_METFV YLEK-EKGFKIFMFHTAIKELIPKDLPEIE-------GIAKSSLPRNFNYYAGGHLHEKI
A2BM15_HYPBU VPRD-RSTVNILLLHQALRE-----VAPNY-------EVELGELPKGFSYYALGHIHLYR
B1L7G0_KORCO CKSL-CNCPSVLMIHQGVKGMIKTFYPELD---------FSHIASTSFNYVAMGHYHNKV
A8A960_IGNH4 --------NSVLLLHVGLCR----ALPFSC--------VDEGLLPKGYKYYALGHVHKPT
MRE11_AERPE ISRT-SSGTLVLLAHMSLDAEMQFDAVASP-----------SDLPSGAKYAALGHLHAPR
MRE11_METKA YRPDPEADVNVAIFHQALPG----TIPDES------EIVEPAYFPEGHDYYAMGHVHVPS
D5U1T5_THEAM ADKA-AGRYDILIMHQNIEN----YFPLDK-------GLSISNIPATPRYVAMGHLHRRI
: * . *. *
MRE11_PYRHO ETNYGDS----PVVYPGSLERWDFGDYAKR--LVWNGVTFREEVGSDKGFYIVEDFTPRF
MRE11_PYRAB ELTYDDA----PVVYPGSLERWDFGDYSLK--LTWNGFQFKEEVGVDKGFYIVEDFKPRF
MRE11_PYRFU ETSYSGS----PVVYPGSLERWDFGDYEVR--YEWDGIKFKERYGVNKGFYIVEDFKPRF
Q5JHP8_THEKO LTSYDIG----KLVYPGSLQRWDFGDYEIR--YRWDGNTFKPTAGNPKGFYIVEDWEPRF
MRE11_ARCFU IYEFDGK----AIAYPGSVERYDLREASKI--VRYRD-ELVLKDGIRKGFILVKNFRPEF
MRE11_HALVD TAEL--DG--TWVTYCGSTERASAS-------ERDPRGYNLVEFTP-----DAVDIRRRT
E4NQX8_HALBP TEQV--DG--TWVTYCGSTERASAA-------ETEARGYNLVTFD------DEVDIRRRS
D8J6A3_HALJB RAEV--EG--TWVTYCGSTERATAS-------ERDGRGYNLVTFED-----GEAHITRRG
L0JP08_NATP1 TAEV--RD--TWVTYCGSTERASAS-------ERADRGYNLVDFDD-----EVAISRRGL
MRE11_HALSA TAQL--GD--TWVTYCGSTERASAS-------ERDPRGYNIVSFSSD--ATTDVAISRKS
Q18JH8_HALWD VETV--ED--AWVTYCGSTERTSTA-------EESARGYNLVTFDT------DVDIRRRS
Q3ISN6_NATPD KQEV--AD--TWVTYCGSTERTSAS-------ERDDRGYNLVTFDG------AVRISRRG
MRE11_METAC KIKVGEEE--TWATYSGSTERNSAS-------ENEPRSYNIITLSG-----EGLEISRRT
MRE11_SULTO VFQLDGG---RIIEIAGSPDILREEEIEGY--EKEGKGATLIDFSGD--IPTIQKINIDV
MRE11_SULAC KDYLDGG---ALIEIAGSPDIMREEEIEDY--QKSKKGATLIDMSGD--LPSINYINVNI
MRE11_SACS2 RLTQDDG---SVIAIAGSPDIMREEEIEGY--EKFGKGAYLIDFSKD--LPILSTINITV
MRE11_METJA LERFNDG----ILAYSGSTEIIYRNEYEDY--KKEGKGFYLVDFSGN--DLDISDIEKID
MRE11_METMP LKPINDGN--SVFSYAGSTDIMSVSEVKDY--KKNGKGFYLGDLSG---DFDINSIQKID
MRE11_THEAC ERRIGPL-----ISYAGSTEIKSENEINGY--LKQGKGVNIVDISNG--EVDLQRIRLKS
MRE11_THEVO EREIGPL-----LSYPGSTELKSDREINGL--LKMGKGINVIDLDNG--VASLHRVKLKK
MRE11_METTH_P CYIEEGYG--PIVYPGTLFGSYAGDLEENA--RGETRGYYLVEFTDR-----AREPEFRE
E3GXV9_METFV IDEEE-----MIFYPGTLFGPSFKDLEKTA--SGLDRGFYIVEFDDE-----VKKYEFKN
A2BM15_HYPBU EFRLGDA----AVVYPGSPEVLRIDEAR----EQPQRYVVLVEVDQR---STKSLERIRL
B1L7G0_KORCO VRRSGNR----VFAYPGSTEIVELREA-----FTSDGSKYILSVDIE---RDGVDVREIK
A8A960_IGNH4 VLEVHGA----PAAYPGSLEATTVDEVLWE--SSDNPLLRRGPLLVDLGGDEAQIVGKLN
MRE11_AERPE IRLDAPT----PYAYPGVLDPLKVEE------INTPGSPLYVDLSGDAPIIEKVKVPRRP
MRE11_METKA -REEKIHG--SPAPYPGSPEPLTFLEVKDERGAHKRRGFFLVEFDRG----GLVEYEFVE
D5U1T5_THEAM LDKRAVEGKNQVIAYPGSIDVLNVEEAEEAR--RNGKGFYIVDLTPE-----EPIVHKIN
MRE11_PYRHO VNIKVRDFIDVVIKGDSER--EIKKAVKASLPHIPRNSYVRFNIKWRKPFDVEWIKEIVN
MRE11_PYRAB IRINARDFIDVHIKGHSEN--EIKKAVKLAVPKIPRNSYVRFNIRWKRPVDVDWIKSIVN
MRE11_PYRFU VEIKVRPFIDVKIKG-SEE--EIRKAIKRLIPLIPKNAYVRLNIGWRKPFDLTEIKELLN
Q5JHP8_THEKO VELNVRPFIDVNIKA-DEE--TAKRELKRLSTKIPEEAFVRLDIRWERPYDVSKLTELIK
MRE11_ARCFU VEIETRELYDVEIEDESVE--GLEKKFLEVLGRADKEGIMVAKLKSSDAVDVRRLSEVAA
MRE11_HALVD LETRPFAFVEVDLAGDE----GIERVRQRVREFDLEDAVVIVELRGEGE-TVTPAAVESF
E4NQX8_HALBP LDTRPFAFVSVELADDE----GAERVREQVRQHDVDDAVAIVEITGEGE-PVTPASIEEF
D8J6A3_HALJB LDTREFVFADVQLAAGE----GIERVLERVGQHDLDGRVVIVTVEGEGE-PLAPAEVESF
L0JP08_NATP1 TDTREFVFVDVDLAEGE----GVDRVQERVRQHDLADAVVIITVEGEGR-PITPAAIEEL
MRE11_HALSA LNTREFVFVDADLGPTD----GTAFIQERLRERALDDAVVVVTITGDGD-TVTPAEIERF
Q18JH8_HALWD LETRPFVFVSVDLATGE----GTERVCDRLREYDLGDAVVVIEITGDGD-SVPPATIETF
Q3ISN6_NATPD IKTRPFVFVDLELGATE----GFNYVRDRLLEYDLDDAVVRVTLDGDGE-DVSPARIESF
MRE11_METAC IPTRNFLFITAKIDGEEKP-YEQIFSAINEHLEEIPESVVFLDISGNSDSVLSFSEIEEY
MRE11_SULTO RKQYVVTLNTNNLREEI-----RKLREKYDTN---NEKKPIFHIILEGK-SIPKNVLMKE
MRE11_SULAC RDQLVLDINVDKIEQSI-----ESVIQKLKENVK-NDKKPILHIELEGTVPIRKDVLMTK
MRE11_SACS2 RPQKVVTINTKNIKKDI-----LTIRDDLIEHNKSENNKPILHIIVEGE-RMRKDLLYKE
MRE11_METJA IECREF-VEVNIKDKKS-----FNEAVNKIERCKN---KPVVFGKIKRE----------F
MRE11_METMP VECRNFLIDKKIKNEND-----YKKTVEELQNLQSEKKKPILYCDIVEN----------L
MRE11_THEAC VRPQIRVESDADNYVHE-----ISEKLSSLRVKD-NEKKPLVGLEIHGD---------IS
MRE11_THEVO VRYQFKVESDPENYLEE-----IKSILDKYANAI-GEKKPIVNLIINGQ---------IS
MRE11_METTH_P IRPAEFEYIECDVTGKNSQ-DAYHQIGREIAGHDVTGKVVMLKIRGELSSGRTSDIDSAS
E3GXV9_METFV VDVAEYEYIKLNNFDNMSPLEARTEIINKLNEKNVENKIVLIKVYGELN-GKVSSIDFQG
A2BM15_HYPBU EMPRPIVYKEIIYQGLAEFKSLLVELREKLAKMAAKGVKKPLLYMYVKRLPRGSKTDIYT
B1L7G0_KORCO LETRPFITFSEIIRNTR----DLYSLIERIRNEIKGKERPVICGRIQVKGSLKPGFSTGE
A8A960_IGNH4 VYNRKQIIKKYELPKDYKR---ALAEAESVPQGAVVHLYLTGKVGKDAVRAISSKFQARA
MRE11_AERPE QYRIEVDIGDGGSIYNAVN-RGLRRVLANVRASREDWLKPLIHVIIKSDKPISKARVIAE
MRE11_METKA VEWSRELSVVEVSGERWEEELRRRVRRGQIVKVVAKDTGASPEEVEKVAIEAGADRCVVE
D5U1T5_THEAM VETTPFEYVEASAKESDWRPKIAEALARLAKQVSQGNKGILYVKITMSTGETVSLERIIN
MRE11_PYRHO AEYLRIHTAIIKDEKSMN-GESVDIKS-FFTEQEWKVIDLASS-----DEFESYIEKIV-
MRE11_PYRAB AEYVRVNPIIIKEERGPD-GKDLDVKK-FFTELEWKIIELASE-----KEYEYYLNQII-
MRE11_PYRFU VEYLKIDTWRIKERTDEE-SGKIGLPSDFFTEFELKIIDILGEKDF--DDFDYIIKLIT-
Q5JHP8_THEKO ARYVYVRTRFERKLTGRTPSGEVPKPEEYFIPVELKAINLTGEKAI--ESIEEVVELFLG
MRE11_ARCFU KRVRYAEIRFERILEEIE-EVEIKQESEFFTEFELKLLELLRGEMDEDEVYSLVVEHYLS
MRE11_HALVD AVEEGALVARVNDKRDIDDDG-DLATDVTFADPDDAVRERVREMGLSSAALDVDETVRAS
E4NQX8_HALBP LSERGALVARVTDRRSMETE---TEVDVSFADPDDAVRERVSDLGLSTAALDVDETVRAS
D8J6A3_HALJB AREGGALIARVNDKREIESG---EPADVSFSDPDAAVRERLREMGLSGAASDIDETVRAS
L0JP08_NATP1 AIDRGALVARVNDRRELPDE--DEDVSVSFADPDAAVRERVRELGLSDAAREIDETVRTD
MRE11_HALSA GDDRGALLTRVNDRREFDTGDDAPDVDVSFADPDDAVEQRVRDLGLDEPARDVDRIVRDD
Q18JH8_HALWD ATDHGALVARVTDRREHPEER-NIDTTVSFADPDAAVEQRIRELDLSTAAHDIDTMIRSD
Q3ISN6_NATPD ATDEGALVARVTDNRTIDVDA--DAPDIAFADPDKAARERVRELGLSEMGRQLDETVRDG
MRE11_METAC LLSKGALVSKVKDARIKETLP-EEVAKVAFSDPDHAVAEEIRRMSLNDGGLIVDEIIRSP
MRE11_SULTO LQEINNFAPYWRIYKDNTKEKDEKDVKIDLPTDTTIENLIYNYLVKIANFSETEARMIVD
MRE11_SULAC LQALRDYVEHYRIYKNNIVSIKEENLKTKLKTTYSSLNDIIADYLKGIGYTDEETKIIID
MRE11_SACS2 LLPLNDVALYYRIYKDETTQTVD-NLSYTLPRDKGLDKIIIEYLTKYEKFSEDEANLILQ
MRE11_METJA KPWFDTLKDKILINKAIIVDDEFIDMPDNVDIESLNIKELLVDYANRQGIDGDLVLSLYK
MRE11_METMP FNSFNDEIANLTLYKRISRIDE--NLEESLIINESSIEEIFQEYIKNKEMDVNFVYGLYK
MRE11_THEAC METVMQDISKFDNAIFSRPKIRKDPKIPNIHTETADLREYFRAYLGDERLADLAMKIMAH
MRE11_THEVO MEEVYEDLKKINGAIFNRPQILKIVDMPNVPSGSSELREYFQAFLKDQKLTDLAMKVFQH
MRE11_METTH_P IREKLESMGARVVQINRYGLSTREIQKVRVVESDVPRLERRIFREKLAGLDIRNRRLMEE
E3GXV9_METFV IKRHVLNNGAIYVAINYHNLKSKEQAKVKVRTSDANKIEEKIFSEKIKNIDIKNPLLKNK
A2BM15_HYPBU LVERILGSYILDYKLNIETVIENVPKTVQSAAATINIENILRELLGNDELAQLAVKLIEI
B1L7G0_KORCO IKRSLSSDALHIAVKERFEEREEVSDEAPLLGLEDTISQLIGSLKIDEDIKSLAIRIFDI
A8A960_IGNH4 LTVRVNFLAEEEEEVEETVTNFTGLEDLIIEFYGKELGRLLYELVKAAQERRSDELKRVA
MRE11_AERPE ARKAAGGADVLLKIHWKIVAGGEHAGTSPGLQGEGPLDLAKIAAEYYKIPLNAASTILHD
MRE11_METKA LRERRREVEEGDETEGPLDLEGIIREGVKRARAATLTRVDVPDDVVVEVALEILRGVRED
D5U1T5_THEAM LIIEEKKKKLPGSHDLIFHKLERKLAQETLEKPSGQLQTPRGELETLADYLTRELGAKPE
MRE11_PYRHO ------------------DILSGYE-KKEERE----------------------------
MRE11_PYRAB ------------------DLLASEEGKVEAKI----------------------------
MRE11_PYRFU ------------------EGKVEEEGPLEEAV----------------------------
Q5JHP8_THEKO EGWDEKLPKKTEEPERKEDATAKKEGGPEKEKRP--------------------------
MRE11_ARCFU GGALK------QEEGAEERVVEEETEKKVEEQFK--------------------------
MRE11_HALVD K---------VADSNVRDEVRERVESLL-SDDPD--------------------------
E4NQX8_HALBP K---------TADANVREEVKTRVDSLLESDDLD--------------------------
D8J6A3_HALJB K---------LADSNVRGAVEERVTSLL-EEDPA--------------------------
L0JP08_NATP1 D---------LADANVRERVERRVRDLL-EEDTS--------------------------
MRE11_HALSA T---------LADAAVRERVIQRAEAVL-DDDAD--------------------------
Q18JH8_HALWD S---------ISDSNIRNTVTEEISELLNNESLD--------------------------
Q3ISN6_NATPD E---------IADSNLSDEIERRVESALEDGGLE--------------------------
MRE11_METAC D---------VVRSRVDEETENRLLRLIETIDFEDPDFRIEIPASPISSTDSIDPVSPIN
MRE11_SULTO I---------INRADEREYVKEELMKMIGVENDNKKN-----------------------
MRE11_SULAC I---------INEEDEK-KVEELLKKFAGVEDK---------------------------
MRE11_SACS2 M---------IKNVESDEIVNEILKKLTGVNL----------------------------
MRE11_METJA A---------LLNN-ENWKELLDEYYNTKFRG----------------------------
MRE11_METMP K---------LLENDEDSLLYVNDYFKGNY------------------------------
MRE11_THEAC S---------RSKDIDGIMKEIEVLYGDNRQDSPD-------------------------
MRE11_THEVO T---------ADGDKEAIIREAAGEAIDN-------------------------------
MRE11_METTH_P ----------------GDSIAVELLRRLENEKAP--------------------------
E3GXV9_METFV I---------------GVRVSKELLRILRQPMKP--------------------------
A2BM15_HYPBU LGGESE----KHALKEAYSIVAQEFGLDREAGLL--------------------------
B1L7G0_KORCO WYR---------EGKRGEDFLNEVMRMVEEP-----------------------------
A8A960_IGNH4 E---------EIFESGAWRRAQRASSQRGRRR----------------------------
MRE11_AERPE LAEAAAEKDELRVREILETLATTVSQDTWKRILYMR------------------------
MRE11_METKA NPPDLGDVEGIVAGEPPSEGSEESSEEPEESDGE--------------------------
D5U1T5_THEAM EASKLAEHLSSLKEAFRQGDEESLEQTLEELAKA--------------------------
MRE11_PYRHO ------------------------------------------------------------
MRE11_PYRAB ------------------------------------------------------------
MRE11_PYRFU ------------------------------------------------------------
Q5JHP8_THEKO ------------------------------------------------------------
MRE11_ARCFU ------------------------------------------------------------
MRE11_HALVD ----------AFVAAER-------------------------------------------
E4NQX8_HALBP ----------AFTPADTDGTESEGKESTPSATDV--------------------------
D8J6A3_HALJB ----------AFEPAAT-------------------------------------------
L0JP08_NATP1 ----------ALEPAPDR------------------------------------------
MRE11_HALSA ----------AAD-----------------------------------------------
Q18JH8_HALWD ----------AFTQTSSADTNTFDKTTSTSPEGTQSDSSILSADYTTNSPSSNKETENHT
Q3ISN6_NATPD ----------DIAGTAA-------------------------------------------
MRE11_METAC HPVSSADSVSAVSPESSADHVSPDIIENNEKPIPAVEAEKIETLDPAGETEFVAGIAGKT
MRE11_SULTO ------------------------------------------------------------
MRE11_SULAC ------------------------------------------------------------
MRE11_SACS2 ------------------------------------------------------------
MRE11_METJA ------------------------------------------------------------
MRE11_METMP ------------------------------------------------------------
MRE11_THEAC ------------------------------------------------------------
MRE11_THEVO ------------------------------------------------------------
MRE11_METTH_P ------------------------------------------------------------
E3GXV9_METFV ------------------------------------------------------------
A2BM15_HYPBU ------------------------------------------------------------
B1L7G0_KORCO ------------------------------------------------------------
A8A960_IGNH4 ------------------------------------------------------------
MRE11_AERPE ------------------------------------------------------------
MRE11_METKA ------------------------------------------------------------
D5U1T5_THEAM ------------------------------------------------------------
MRE11_PYRHO --------------------------------------------------KKESKIR-KF
MRE11_PYRAB --------------------------------------------------DAKREEK-KF
MRE11_PYRFU --------------------------------------------------KKVSEEKGKT
Q5JHP8_THEKO ----------------------------------------------KTQGKEQRETKERK
MRE11_ARCFU ----------------------------------------------GDEEADEAERRAEE
MRE11_HALVD ----------ESDAEAEESESVEDAADGEDAAAVED--------TAETAAEAATDTDTET
E4NQX8_HALBP --------TTETDATDESDDSIETAATTEANTTDEDEVAVETHGTTDTDATVGTDETTDT
D8J6A3_HALJB ----------APDGESPSESPTESAD-------------------GDTPGTAGTAESTDR
L0JP08_NATP1 --------EPADDDVTTVADELETAEADSSGAGADGETEPT---AADGDGGAATDEDGAV
MRE11_HALSA -----------DDGRPTTVEEFQ-------------------------------------
Q18JH8_HALWD PFVQQPQSTVKDDDTDTKIDSDDMSNDENMDIIADTNRFTNISQDANTDTDTTANIGSDS
Q3ISN6_NATPD -----------DADTGDNGEAGDSGATTGSESE-----------RADGKTGPSDTGDAGE
MRE11_METAC ETFRAPVRIKNSESLNEALKKSYEAPDKVREAPDVNPEPPEPLPAFKNIGSPETFGSCET
MRE11_SULTO ------------------------------------------------------------
MRE11_SULAC ------------------------------------------------------------
MRE11_SACS2 ------------------------------------------------------------
MRE11_METJA ------------------------------------------------------------
MRE11_METMP ------------------------------------------------------------
MRE11_THEAC ------------------------------------------------------------
MRE11_THEVO ------------------------------------------------------------
MRE11_METTH_P -------------------------------------------------GENKSEYEKRI
E3GXV9_METFV -------------------------------------------------GEKKKDYEERI
A2BM15_HYPBU ------------------------------------------------------------
B1L7G0_KORCO ------------------------------------------------------------
A8A960_IGNH4 ------------------------------------------------------------
MRE11_AERPE ------------------------------------------------------------
MRE11_METKA ----------------------------------------EVGLEVEEVKVESRGTSSEG
D5U1T5_THEAM ----------------------------------------GFWSRIGIPEEYIKLEEAKP
MRE11_PYRHO ERPK-------NPGDLTAWLRGG-------------------------------------
MRE11_PYRAB VRPK-------NPGDIMAWVKG--------------------------------------
MRE11_PYRFU VRQKIESIPKKKRGTLDSWLGGAR------------------------------------
Q5JHP8_THEKO DSEKKVVKRPSKGSNLLDWLGGGR------------------------------------
MRE11_ARCFU TEKAKSTKKARKPKTLLDFLGVEEE-----------------------------------
MRE11_HALVD TADTDSETAADPAASRDSSLGDFA------------------------------------
E4NQX8_HALBP DTTVDTDTEDDTATDADAENGNAEPNQQFTMEDF--------------------------
D8J6A3_HALJB PEGASADRQAQSSMEEYL------------------------------------------
L0JP08_NATP1 ADAADGSGEGDARADDDADADADTASLGDFA-----------------------------
MRE11_HALSA ------------------------------------------------------------
Q18JH8_HALWD NAEPSIDRTEETELSDDESDTSETDESNSASSQFTMEDF---------------------
Q3ISN6_NATPD TGDARTEAESNESSQTQETDGQPAENGQSSMEEYL-------------------------
MRE11_METAC TVSSEVPEKGGERTELEDDAVNKTEKETGKLSGFGVEAGSEKEDADRIEKPAHVPDKAEK
MRE11_SULTO ------------------------------------------------------------
MRE11_SULAC ------------------------------------------------------------
MRE11_SACS2 ------------------------------------------------------------
MRE11_METJA ------------------------------------------------------------
MRE11_METMP ------------------------------------------------------------
MRE11_THEAC ------------------------------------------------------------
MRE11_THEVO ------------------------------------------------------------
MRE11_METTH_P IEDAGDVLGLDLGGDGT-------------------------------------------
E3GXV9_METFV LEESMSIFNIK-------------------------------------------------
A2BM15_HYPBU ------------------------------------------------------------
B1L7G0_KORCO ------------------------------------------------------------
A8A960_IGNH4 ------------------------------------------------------------
MRE11_AERPE ------------------------------------------------------------
MRE11_METKA MSRAGSKLGSSGRPSLDRWIG---------------------------------------
D5U1T5_THEAM PAAGRSEPNARKPSRLTEYFKR--------------------------------------
MRE11_PYRHO -------------------------
MRE11_PYRAB -------------------------
MRE11_PYRFU -------------------------
Q5JHP8_THEKO -------------------------
MRE11_ARCFU -------------------------
MRE11_HALVD -------------------------
E4NQX8_HALBP -------------------------
D8J6A3_HALJB -------------------------
L0JP08_NATP1 -------------------------
MRE11_HALSA -------------------------
Q18JH8_HALWD -------------------------
Q3ISN6_NATPD -------------------------
MRE11_METAC PVKQSQRKGKGKSAVPRQYNLGDYL
MRE11_SULTO -------------------------
MRE11_SULAC -------------------------
MRE11_SACS2 -------------------------
MRE11_METJA -------------------------
MRE11_METMP -------------------------
MRE11_THEAC -------------------------
MRE11_THEVO -------------------------
MRE11_METTH_P -------------------------
E3GXV9_METFV -------------------------
A2BM15_HYPBU -------------------------
B1L7G0_KORCO -------------------------
A8A960_IGNH4 -------------------------
MRE11_AERPE -------------------------
MRE11_METKA -------------------------
D5U1T5_THEAM -------------------------