CLUSTAL format seed alignment for MF_02227
_____________________________________________________________________________
Features found in the protein:
- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
RPE_CHLTR ----MREEAMKKQ-GVLVAPSIMGADLACIGREARNIEESGADLIHIDVMDGHFVPNITF
RPE_CHLMU ---------MKKQ-GVLIAPSIMGADLACLGDAARNIEESGANLIHIDVMDGHFVPNITF
RPE_CHLPN ---------MKKQESVLVGPSIMGADLTCLGVEAKKLEQAGSDFIHIDIMDGHFVPNLTF
RPE_AQUAE --------------MKLLAPSILAGDWWCIGEQIQATIRGGADILHYDVMDGHFVPNITA
RPE_HELPJ ---------------MKVAPSLLSADFMHLAKEIESV--SNADFLHVDVMDGHYVPNLTM
RPE_METJA --------------MIKIGASILSADFGHLREEIKKAEEAGVDFFHVDMMDGHFVPNISM
A7HLQ2_FERNB --------------MAIISASILAADLSRLKEELERV-KPFIDEIHLDVMDGHFVPNLTF
RPE_BACSU --------------MIKVAPSILSADFAALGNEIKDVEKGGADCIHIDVMDGHFVPNITI
RPE_SYNY3 -----------MSKNIVVAPSILSADFSRLGEEIKAVDEAGADWIHVDVMDGRFVPNITI
RPE2_CUPNH MHATEPNTGHGSQRAIRLAPSILSADFARLGEEVCAIEAGGADLVHFDVMDNHYVSNLTI
RPE1_CUPNH MHATELNTGHGSQRAIRLAPSILSADFARLGEEVCAIEAGGADLVHFDVMDNHYVPNLTI
RPE_ECOLI ------------MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTI
RPE_HAEIN ------------MKPYLIAPSILSADLARLGDDVQNVLNAGADVIHFDVMDNHYVPNLTF
RPE_BUCAI ------------MNKFFLAPSILSADFARLGEDIKKVIDAGSDLIHFDVMDNHYVPNLSM
RPE_BUCAP ------------MKKFFLASSILSADFARLGEDTKKAIDAGSDWIHFDVMDNHYVPNLTM
RPE_BUCBP ------------MKKFLLSSSVLSANFSRLGEDIFDVLKSGSDMIHYDVMDNHYVKNLTF
RPE_RHORU -----------MTRAIRIAPSLLSADFAISRPRCPSDGRTGADILHFDVMDNHYVPNLTV
RPE_TREPA -----------MERSFTLAPSLLSADFSALDRALVYLEAHGAQWVHLDVMDGHFVPNLTF
F4LQE3_TREBD ------------MKTPLLAPSLLSADFLHLDSALKRIEQGGASFVHIDVMDGRFVPQISY
G7V9N0_THELD ----MARSISVSSQEVLIAPSVLSANPLRMAEAVNAL-SGEYDMLHVDIMDGHFVPNLSY
B8E0X1_DICTD -------------MEIKVYPSLLSADLLNMERSIEIV-KDLSDALHVDIMDGHFVPNLSY
G8UKI0_TANFA -------------MSHKIAPSLLSADFLNLQRDIEMINRSEADWLHLDVMDGVFVPNISF
RPE_YEAST ------------MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITL
RPE_CANGA ------------MVKPIIAPSILASDFANLGCECHRVINSGAEWLHIDVMDGHFVPNITL
RPE_HUMAN -----------MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITF
M9SG71_METAX --------------MTKIAPSMLSCDFSRLGEELVRVEKSGADWAHLDVMDGMFVPNLTF
RPE_MYCTU --------MAGSTGGPLIAPSILAADFARLADEAAAVNG--ADWLHVDVMDGHFVPNLTI
Q2J847_FRACC ------------MATAQIYPSLLAADFGRIADAALAVEGQ-ADWLHVDVMDYHFVPNLAF
E6JYL7_PARDN ----------MKLMTIKIAPSILSADFVNLQSELEAIKT--ADLVHVDVMDHHFVPNLTM
RPE_MYCPN --------MLNLVVNREIAFSLLPLLHQFDRKLLEQFFADGLRLIHYDVMD-HFVDNTVF
RPE_MYCGE -------------MATKVVFSLLPLLNRFDKSLLESYFQDGLRLIHYDVMD-QFVHNTAF
RPE_ENCCU --------MHLGMLKKRIGISILDCNFGNLEEELGELKRNGVTNIHLDVMDTTFVKNITF
: *:: * *:** :* :
RPE_CHLTR GPGVVAAINRSTE----------------LFLEVHAMIYTPFEFVEAFVKAG-ADRIIVH
RPE_CHLMU GPGIIAAINRSTD----------------LFLEVHAMIYTPFEFVEAFVKAG-ADRIIVH
RPE_CHLPN GPGIIAAINRSTD----------------LFLEVHAMIYNPFEFIESFVRSG-ADRIIVH
RPE_AQUAE GYEILSHIRKRAS----------------LPIDAHLMIENPDKYIPKFVEAG-ANWISVH
RPE_HELPJ GPVILENVTQMSQ----------------VPLDVHLMVENASFFVELFAPLN-PQIISIH
RPE_METJA GIGIAKHVKKLTE----------------LPVEVHLMVENVDLFVNEFEEM---DYITFH
A7HLQ2_FERNB GYPMIETLRTFTD----------------LPIDAHLMVTNPDDHIKLFIEKG-ATRVTIH
RPE_BACSU GPLIVEAVRPVTD----------------LPLDVHLMIEEPDRYIPAFAKAG-ADILSVH
RPE_SYNY3 GPLIVDAIRPLTK----------------KTLDVHLMIVEPEKYVEDFAKAG-ADIISVH
RPE2_CUPNH GPLVCEAIRPLVS----------------IPIDVHLMVEPVDALIPMFAKAG-ANLISFH
RPE1_CUPNH GPLVCEAIRPLVS----------------IPIDVHLMVEPVDALIPLFAKAG-ANIISFH
RPE_ECOLI GPMVLKSLRNYGI---------------TAPIDVHLMVKPVDRIVPDFAAAG-ASIITFH
RPE_HAEIN GPAVCQALRDYGI---------------TAPIDVHLMVKPVDRIIPDFAKAG-ANYITFH
RPE_BUCAI GPMILESLRNYNI---------------TAPIDVHLMVKPVDNLIPQFAKAG-ATFITFH
RPE_BUCAP GPMILKALRNYNI---------------TVPIDVHLMVKPVDNLIPQFAEAG-ADFITFH
RPE_BUCBP GPIVLESLRSVEKIK-------------SMVIDVHLMTCPVDDLIIKFAKLD-VNIISFH
RPE_RHORU GPLVCAALRPHTS----------------LPIDVHLMTRPVDPLIDSFAEAG-ADMITFH
RPE_TREPA GAPVLRCLRSKTH----------------LPFDVHLMVSRPADLIEDFVQAG-ADFLTFH
F4LQE3_TREBD GQPVVSALRPHTE----------------LPFDVHLMIEQPENHIDSFIRAG-ADYLTFH
G7V9N0_THELD GPDLVRSMREEWPD---------------VLLDTHLMVERPQDFIDVFADAG-TDILTVH
B8E0X1_DICTD GPSLVKALRNRYS----------------IPLNVHLMVEKPENFVDMFIEAG-ASHLGFH
G8UKI0_TANFA GFSVLDALKGVCT----------------KPMDVHLMIIEPQKFIREVAAAG-AYMMNVH
RPE_YEAST GQPIVTSLRRSVPRPGD---ASNTEKKPTAFFDCHMMVENPEKWVDDFAKCG-ADQFTFH
RPE_CANGA GQPIVTSLRRAVPRSQEEEKASGEVARPTAFFDCHMMVEEPEKWVADFAKAG-ADQFTFH
RPE_HUMAN GHPVVESLRKQLG--------------QDPFFDMHMMVSKPEQWVKPMAVAG-ANQYTFH
M9SG71_METAX GAPIIKCARHWTD----------------IPFDAHLMIEDPVRYVEDFAKAG-CDSITVH
RPE_MYCTU GLPVVESLLAVTD----------------IPMDCHLMIDNPDRWAPPYAEAG-AYNVTFH
Q2J847_FRACC APDTVTALRAVTD----------------TPLDCHLMIDDPDRWAAGYAERG-AANVTIH
E6JYL7_PARDN GEPIVKRICEVSP----------------IPVDAHLMIEDPDRWAPEFARCG-ARSVTFH
RPE_MYCPN QGEHLDELQQIGF-----------------QVNVHLMVQALEQILPVYLHHQAVKRISFH
RPE_MYCGE KGEYLDELKTIGF-----------------DVNVHLMVEQIIPQINFYLSQPNVKRISFH
RPE_ENCCU GPCIINRILEHDF-----------------VFDVHMMVESPLDIIMQIDLER-VSLVTIH
.: * * .*
RPE_CHLTR FE--AAENIKEIISYIQKCGVQAGVAFSPETSIEFVTSFIPLCDVILLMSVHPGFCGQKF
RPE_CHLMU FE--AAENLKEILDYIRKCGVQAGIAFSPETSIEFISAFIPLCDVILLMSVQPGFCGQKF
RPE_CHLPN FE--ASEDIKELLSYIKKCGVQAGLAFSPDTSIEFLPSFLPFCDVVVLMSVYPGFTGQSF
RPE_AQUAE IE--NNYHIHRTLQLIKELGAKAGVVVNPGTSLSAIEEALYYADYVLLMSVNPGFSGQKF
RPE_HELPJ AE--NEKHPHRVLQLIKSSGITPGIVLNPHTHEESIKYLLESVGLVLLMSVNPGFGGQKF
RPE_METJA IE--AVKFPFRIINRIKSIGAKPIVALNPATPLDAIEYILGDVYAVLVMTVEPGFSGQKF
A7HLQ2_FERNB QE--TCYHLHRSVELIKSLGAEAFVAINPATSIYTLEEILSYADGILVMTVNPGFSGQKF
RPE_BACSU AE--ACPHLHRTIQLIKEQGVKAGVVLNPHTPVQVIEHVFDDLDLVLLMTVNPGFGGQKF
RPE_SYNY3 VEHNASPHLHRTLCQIRELGKKAGAVLNPSTPLDFLEYVLPVCDLILIMSVNPGFGGQSF
RPE2_CUPNH PE--ASRHVDRTIGLIRDHGCKAGLVLNPATPLSWLDHTLDKLDLVLLMSVNPGFGGQAF
RPE1_CUPNH PE--ASRHVDRTIGLIRDHGCKAGLVLNPATPLGWLDHTLDQLDLVLLMSVNPGFGGQAF
RPE_ECOLI PE--ASEHVDRTLQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSF
RPE_HAEIN PE--SSEHIDRSLQLIRDCGCKSGLVFNPAMPLSYLDYVLDKVDVVLLMSVNPGFGGQSF
RPE_BUCAI PE--ATLHIERTLNLIKENGCKAGLAFNPATPLNFLDYILEKLDLILLMSVNPGFGNQSF
RPE_BUCAP PE--STDHIDRTLNLIKECGCKAGLALNPATSLNFLDYVMEKLDLILLMSVNPGFGNQSF
RPE_BUCBP PE--STNNVEKTIKLIKSYGCKVGLALNPLTPLCVLDNVLDKIDLILLMSVNPGFPGQKF
RPE_RHORU PE--ASDHVHRSVQMIRKRGLKAGVALNPASPLSLLDHILEDLDLVLIMSVNPGFGGQSF
RPE_TREPA IE--AEVHAHRLIHAIRGRGVKVGISLVPSTPVAALSEVLPFVDLVLVMTVNPGFSGQQM
F4LQE3_TREBD WE--NTVHHHRIIGRIHDAGKKAGIAVVPSTPIAVLEEILPYLDLVLVMTVNPGFGGQAF
G7V9N0_THELD VE--TAPHLHRVLEMIRAKGCVPGVSINPGTPVEWLKPVLPIVGLVLVMSVNPGFGGQSF
B8E0X1_DICTD VE--ATHHPQRLLKYIRDHNIRPFITLNPATPLNTIEYLLGELDMVLIMTVNPGYGGQEF
G8UKI0_TANFA YE--ACTHLHRTIHAIKDAGMKAGVTLNPHTPTGLLEDIIQDVDMVLLMSVNPGYAAQSF
RPE_YEAST YE--ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF
RPE_CANGA YE--ATKDPLSLVKLIKENGIKAACAIKPGTPVDVLFELAPYLDMALVMTVEPGFGGQKF
RPE_HUMAN LE--ATENPGALIKDIRENGMKVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKF
M9SG71_METAX TE--AEGDIMAAVDKIHDLGLKAGITMNPPTDVHDLDRYLDRVDLVLIMTVNAGFGGQKF
RPE_MYCTU AE--ATDNPVGVARDIRAAGAKAGISVKPGTPLEPYLDILPHFDTLLVMSVEPGFGGQRF
Q2J847_FRACC AE--AVSDLPRTTRAIRAAGARTGLAVKPNTPVEHYLDDLHRFDLLLLMTIEPGFGGQTF
E6JYL7_PARDN MG--AAHAPVRLARQLHDMGAKACFAVRPAEPVESIFDILDEFDMILIMTVEPGFGGQKF
RPE_MYCPN VEPFDIPTIKHFIAQIKQAGKQVGLAFKFTTPLVNYERLVQQLDFVTLMSVPPGKGGQAF
RPE_MYCGE VEPFSFAKIKELIQLVKENGKEVGLAFKFTTNLQLYQPFFTTIDFITLMSVPPGKGGQAF
RPE_ENCCU SE---VCDKAGVAEYLRKRNVLFGIALNPETQVD--DAEMRSADFVLIMSVKPGFGGQKF
:: . . :*:: .* * :
RPE_CHLTR IPDTIERIQFVKQAIQVLGREGS--CLIEVDGGIDKESARACREAGADILVAASYFFEKD
RPE_CHLMU IPDTIEKIRFVRQAIQTLGKEGS--CLIEVDGGIDEESARACREAGADILVAASYFFKKD
RPE_CHLPN LPNTIEKIAFARHAIKTLGLKDS--CLIEVDGGIDQQSAPLCRDAGADILVTASYLFEAD
RPE_AQUAE IERSIERLRILKEMRDRINPSC----LIEIDGGIKENNIAEVVRAGADVVVVGSGIFGAK
RPE_HELPJ LDLVLEKCLKVKELIKRYNPSC----LLEVDGGVNDKNIFELQQAGVDVVVSGSYIFESK
RPE_METJA IPVMTKKIRKLKSMIVENGYDT----KIFVDGGINVETAPLAVKAGADVLVAASAIFGKD
A7HLQ2_FERNB IPTMMEKIKRLNEIRKERNLSF----KIAVDGGVGNSNAQDLINIGVNILVMGYGVFRND
RPE_BACSU IHSVLPKIKEVKRMADEKGKKD---LLIEVDGGVNKETAPLVIEAGANLLVAGSAVYGQS
RPE_SYNY3 IPEVLPKIRALRQMCDERG-LD---PWIEVDGGLKPNNTWQVLEAGANAIVAGSAVFNAP
RPE2_CUPNH IPGVLDKVRQARARIDRQVAAGGRPVWLEIDGGVKADNITEIARAGADTFVAGSAVFGAP
RPE1_CUPNH IPGVLDKVRQARARIDRQVDAGGRPVWLEIDGGVKADNIAAIARAGADTFVAGSAVFGAP
RPE_ECOLI IPQTLDKLREVRRRIDESGFD----IRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQP
RPE_HAEIN IPATLKKLQQARKIIDESGYD----IRLEVDGGVKVDNIAEIAAAGADMFVAGSAIFGKP
RPE_BUCAI LPSTFNKLREVRKIIDANFSD----ILLEVDGGVKLDNIADIACAGANVFVMGSGLFKYS
RPE_BUCAP LPTSFNKLREVRKKIELNSSN----ILLEVDGGVKLENISEVAFSGANVFVIGSGIFGYT
RPE_BUCBP IPSILNKIRIVRELIDKSKKN----ILLEVDGGINLSNIFKIASFGTDIFVIGSAIFNSI
RPE_RHORU IPSALPKIAALANGRRRACRG------DRVDGGVNPADARALARPGADILV-RLAIFGAS
RPE_TREPA IAHCLSKVSALVQMRTERGYS----YMISVDGGIDCRTLPQALDAGADVIVSGSAFFSGT
F4LQE3_TREBD IPGCARKITELRRIKAERGYG----FLISADGGINGQTLAAVLDAGTDVVVSGSAFFSGT
G7V9N0_THELD IPEVLEKVKTLKCWKETGPFD----YLIEIDGGISTQNVGEVVRAGCDVVVAGSAIFKAQ
B8E0X1_DICTD LHFSLKKIKSLREMAVKEGIN----LDIMVDGGIDLHTAPLVIEAGANVLISGNSIFNSE
G8UKI0_TANFA IQHSVLKVAKLKQMITARGLP----TLIEVDGGVNKETARPLLDAGADVLVAGSSIFKSS
RPE_YEAST MEDMMPKVETLRA----KFPHL----NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA
RPE_CANGA MPDMMPKVEALRT----KFPHM----NIQVDGGLGKETIGVAAKAGANVIVAGTSVFTAS
RPE_HUMAN MEDMMPKVHWLRT----QFPSL----DIEVDGGVGPDTVHKCAEAGANMIVSGSAIMRSE
M9SG71_METAX HEECIPKIEYVKKWAEDHNPGL----EISVDGGINRETGKRCVEAGANVLVAGSALFKLD
RPE_MYCTU IPEVLSKVRAVRKMVDAGELTI----LVEIDGGINDDTIEQAAEAGVDCFVAGSAVYGAD
Q2J847_FRACC MTEVLPKIEAARRLLDARGLDL----WLQIDGGVNAGTIERAAVAGVDVFVAGTAVFGAA
E6JYL7_PARDN LSNQMGKVRRLRDEITRRGLST----SIQVDGGVSPTTAPIVAEAGADVLVAGSAVYGVK
RPE_MYCPN NSAVFNNLKQAHKYHC----------SIEIDGGIKLDNIHQI-QDDVNFIVMGSGFIKLE
RPE_MYCGE NEAVFTNLKIANHYNL----------KIEIDGGIKVNNIDQI-KAFVDFIVMGSGFIKLE
RPE_ENCCU QEECLAKVEEVRRYGK----------MVGIDGGIEMSNIGRI--TGADYAVVGSGYFRSG
. ***: : :
RPE_CHLTR SINMKEKVLLLQGEEHGAK--------------
RPE_CHLMU SINMKEKVLLLQGEEHGAK--------------
RPE_CHLPN SLAMEDKILLLRGENYGVK--------------
RPE_AQUAE DIEAQTRKLKSLMLSAVSV--------------
RPE_HELPJ DRKLAIEGLQNVRQPLA----------------
RPE_METJA DVKTAVKNLREAALEALNKDFLTKSFNSNEEKQ
A7HLQ2_FERNB ----KLHELNKFRM-------------------
RPE_BACSU DRKKAISEIRGSK--------------------
RPE_SYNY3 NYAEAIAGVRNSKRPEPQLATV-----------
RPE2_CUPNH DADGGYRGILHRLREAATIT-------------
RPE1_CUPNH DADGGYSSILYRLREAATVT-------------
RPE_ECOLI DYKKVIDEMRSELAKVSHE--------------
RPE_HAEIN DYKQVIDQIRTQLASVSA---------------
RPE_BUCAI NYKLVIEKIRKKLEYAHSRSIH-----------
RPE_BUCAP DYNVIIKKIRKKLKNVYSTSIH-----------
RPE_BUCBP NYDLTIRSFRDVLKNINCKK-------------
RPE_RHORU DRAKAIASIRGAAESGLGQEAA-----------
RPE_TREPA LRSLLCKDSSGA---------------------
F4LQE3_TREBD LGWEL----------------------------
G7V9N0_THELD SPYETAREMRRIAAEAKKIGR------------
B8E0X1_DICTD NPREVIIKMKSIRYKEV----------------
G8UKI0_TANFA NPIETIRELKAI---------------------
RPE_YEAST DPHDVISFMKEEVSKELRSRDLLD---------
RPE_CANGA DPHEVISFMKEEVRKELKAKHILGDETKH----
RPE_HUMAN DPRSVINLLRNVCSEAAQKRSLDR---------
M9SG71_METAX DMSQEISLWKGYGPDAER---------------
RPE_MYCTU DPAAAVAALRRQAGAASLHLSL-----------
Q2J847_FRACC DPGQAVERLREQALRAAPRLSPPAPRSAVGPA-
E6JYL7_PARDN NPADAIAAIRQKAEAAFRR--------------
RPE_MYCPN RWQRQQLLKTNQ---------------------
RPE_MYCGE QWQRQKLLQTI----------------------
RPE_ENCCU DRKKFLRDITDEFLCGSCSG-------------