CLUSTAL format seed alignment for MF_03032
_____________________________________________________________________________
Features found in the protein:
- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
AGO3_HUMAN ------------MEIGSAGPA--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
F7HXC6_CALJA ------------MEIGSAGPA--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
H2PYM8_PANTR ------------MEIGSAGPA--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
H2N805_PONAB ------------MEIGSAGPA--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
AGO3_MOUSE ------------MEIGSAGPI--GAQPLFIVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
AGO3_BOVIN ------------MEIGSAGPV--GAQPLLMVPRRPGYGTMGKPTKLLANCFQVEIPKIDV
E2R0U1_CANLF ------------MEIGSAGPV--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
G3SR29_LOXAF ------------MEIGSAGPV--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
G1L0W7_AILME ------------MEIGSAGPV--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
H0X2D8_OTOGA ------------MEIGSAGPV--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
G1SQM3_RABIT ------------MEIGSAGPV--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
AGO3_CHICK ------------MEISSAGPV--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
F6YI65_MONDO ------------MEIGPAGPV--GAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
F6ZVE5_ORNAN -----------------------------MVPRRPGYGTMGKPIKLLANCFQVEIPKIDV
I3KHJ0_ORENI ------------MEIGTTGAV--GAQSLFSMPRRPGYGTMGKPIKLLANCFQVEIPKMDV
H2SQ93_TAKRU MMCCLIEMTELSLGFLFSGAV--GAQSLFSMPRRPGYGTMGKPIKLLANCFQVEIPKIDV
AGO3_DANRE ------------MEIGTTGAV--GAAPQFSVPRRPGYGTMGKPIKLLANCFQVDIPKMDV
I3K864_ORENI ------------MEIGTTGAV--GAQALFTLPRRPGYGTLGKSIKLLANCFQVEIPKIDV
H2U5L9_TAKRU ------------MEIGTTGVAVGGAQALFTLPRRPGYGTIGKPIKLLANCFQVEIPKIDV
:********:**. *********:***:**
AGO3_HUMAN YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
F7HXC6_CALJA YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
H2PYM8_PANTR YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
H2N805_PONAB YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
AGO3_MOUSE YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
AGO3_BOVIN YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
E2R0U1_CANLF YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
G3SR29_LOXAF YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
G1L0W7_AILME YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
H0X2D8_OTOGA YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
G1SQM3_RABIT YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
AGO3_CHICK YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
F6YI65_MONDO YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
F6ZVE5_ORNAN YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVD
I3KHJ0_ORENI YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKKSLYTANPLPVAPTGVD
H2SQ93_TAKRU YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKKSLYTANPLPVAPAGVD
AGO3_DANRE YLYDVDIKPEKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKKSLYTAQPLPVASAGVD
I3K864_ORENI YLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRLPVYDGKKSLYTVSPLPVATGGVD
H2U5L9_TAKRU YLYEVDIKPDRCPRRVNREVVDSMVQHFKVTIFGDCLPVYDGKRSLYTVKALPVASGGVD
***:*****::************************ ******:****...****. ***
AGO3_HUMAN LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
F7HXC6_CALJA LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
H2PYM8_PANTR LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
H2N805_PONAB LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
AGO3_MOUSE LDVTLPGEGGKDRPFKVSVKFVSRVSWHLLHEALAGGTLPEPLELDKPVSTNPVHAVDVV
AGO3_BOVIN LDATLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
E2R0U1_CANLF LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
G3SR29_LOXAF LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
G1L0W7_AILME LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
H0X2D8_OTOGA LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
G1SQM3_RABIT LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
AGO3_CHICK LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLEPDKPISTNPVHAVDVV
F6YI65_MONDO LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRALPEPIELDKPISTNPVHAVDVV
F6ZVE5_ORNAN LDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVV
I3KHJ0_ORENI LDVTLPGEGGKDRPFKVSIKFVSLVSWHMLHEVLTGRSMPEPLELDKPISTNPVHAVDVV
H2SQ93_TAKRU LDVTLPGEGGKDRPFRVSIKFVSLVSWHMLHEVLTGRSMAEPLELDKPISTNPVHAVDVV
AGO3_DANRE LDVTLPGEGGKDRIFKVTIKFVSLVSWHMLHEVLTGRSTPDPLELDKPISTNPVHAVDVV
I3K864_ORENI LDVTLPGEGGKDRPFKVTIKFVSLVSWHMLHEVLTGRGAPGPLDLDKPLSTNPVHAVDVV
H2U5L9_TAKRU LDVTLPGDGGKDRPFKVTIKFVSLVSWHMLHEVLTGHAASEPVDLEKPVSTNPVHAVDVV
**.****:***** *:*::**** ****:***.*:* . *:: :**:***********
AGO3_HUMAN LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
F7HXC6_CALJA LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
H2PYM8_PANTR LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
H2N805_PONAB LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
AGO3_MOUSE LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
AGO3_BOVIN LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
E2R0U1_CANLF LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
G3SR29_LOXAF LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
G1L0W7_AILME LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
H0X2D8_OTOGA LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
G1SQM3_RABIT LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
AGO3_CHICK LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
F6YI65_MONDO LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
F6ZVE5_ORNAN LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
I3KHJ0_ORENI LRNLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
H2SQ93_TAKRU LRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
AGO3_DANRE LRHLPSMRYTPVGRSFFSSPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
I3K864_ORENI LRHLPSMKYTPVGRSFFSSPKDYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
H2U5L9_TAKRU LRHLPSMKYTPVGRSFFSSPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFY
**:****:**********:*:.**************************************
AGO3_HUMAN KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
F7HXC6_CALJA KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
H2PYM8_PANTR KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
H2N805_PONAB KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
AGO3_MOUSE KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
AGO3_BOVIN KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKSTKEIKGLKVEVTHCGTMRRKYRVCNVT
E2R0U1_CANLF KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
G3SR29_LOXAF KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
G1L0W7_AILME KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
H0X2D8_OTOGA KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
G1SQM3_RABIT KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
AGO3_CHICK KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
F6YI65_MONDO KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
F6ZVE5_ORNAN KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
I3KHJ0_ORENI KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
H2SQ93_TAKRU KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
AGO3_DANRE KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
I3K864_ORENI KAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
H2U5L9_TAKRU KAQPVIQFMCEILDIHNIDEQPRPLADSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVT
***********:*************:****** ***************************
AGO3_HUMAN RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
F7HXC6_CALJA RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
H2PYM8_PANTR RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
H2N805_PONAB RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
AGO3_MOUSE RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
AGO3_BOVIN RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
E2R0U1_CANLF RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
G3SR29_LOXAF RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
G1L0W7_AILME RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
H0X2D8_OTOGA RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
G1SQM3_RABIT RRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCN
AGO3_CHICK RRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCN
F6YI65_MONDO RRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCN
F6ZVE5_ORNAN RRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCN
I3KHJ0_ORENI RRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCN
H2SQ93_TAKRU RRPASHQTFPLQLENGQTVERTVAHYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCN
AGO3_DANRE RRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCN
I3K864_ORENI RRPASLQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCN
H2U5L9_TAKRU RRPASLQTFPLQLESGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCN
***** ********.*********:******.****************************
AGO3_HUMAN IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
F7HXC6_CALJA IVAGQRCIKKLTDNQTSTMIKATARSAPDRG--ISRLVRSANYETDPFVQEFQFKVRDEM
H2PYM8_PANTR IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
H2N805_PONAB IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
AGO3_MOUSE IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
AGO3_BOVIN IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
E2R0U1_CANLF IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
G3SR29_LOXAF IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
G1L0W7_AILME IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
H0X2D8_OTOGA IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
G1SQM3_RABIT IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEM
AGO3_CHICK IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEM
F6YI65_MONDO IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEM
F6ZVE5_ORNAN IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEM
I3KHJ0_ORENI IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPFVQEFQFKVRDEM
H2SQ93_TAKRU IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPFVQEFQFKVRDEM
AGO3_DANRE IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYNSDPFVQEFQFRVRDEM
I3K864_ORENI IVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFRVRDEM
H2U5L9_TAKRU VVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPFVQEFQFRVRDEM
:***************************** **********::*********:*****
AGO3_HUMAN AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
F7HXC6_CALJA AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
H2PYM8_PANTR AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
H2N805_PONAB AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
AGO3_MOUSE AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
AGO3_BOVIN AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIEMWAIACFAT
E2R0U1_CANLF AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
G3SR29_LOXAF AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
G1L0W7_AILME AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
H0X2D8_OTOGA AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
G1SQM3_RABIT AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
AGO3_CHICK AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
F6YI65_MONDO AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
F6ZVE5_ORNAN AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
I3KHJ0_ORENI AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
H2SQ93_TAKRU AHVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
AGO3_DANRE AEVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
I3K864_ORENI AQVTGRVLPAPMLQYGGRVSSEPFMNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
H2U5L9_TAKRU AQVTGRVLPAPMLQYGGR-------NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
*.**************** *************************:*********
AGO3_HUMAN QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
F7HXC6_CALJA QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
H2PYM8_PANTR QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
H2N805_PONAB QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
AGO3_MOUSE QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
AGO3_BOVIN QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
E2R0U1_CANLF QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
G3SR29_LOXAF QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
G1L0W7_AILME QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
H0X2D8_OTOGA QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
G1SQM3_RABIT QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
AGO3_CHICK QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVGPMFRHLKNTYSGLQLI
F6YI65_MONDO QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
F6ZVE5_ORNAN QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
I3KHJ0_ORENI QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLI
H2SQ93_TAKRU QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLI
AGO3_DANRE QRQCREEVLKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADNVEPMFRHLKNTYAGLQLI
I3K864_ORENI QRQCREEILKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLI
H2U5L9_TAKRU QRQCREEILKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYGGLQLI
*******:**.******************************.* **********.*****
AGO3_HUMAN IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
F7HXC6_CALJA IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
H2PYM8_PANTR IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
H2N805_PONAB IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
AGO3_MOUSE IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
AGO3_BOVIN IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
E2R0U1_CANLF IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
G3SR29_LOXAF IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
G1L0W7_AILME IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
H0X2D8_OTOGA IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
G1SQM3_RABIT IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
AGO3_CHICK IVILPGKTPVYAEVKRAGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
F6YI65_MONDO IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
F6ZVE5_ORNAN IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
I3KHJ0_ORENI IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNIL
H2SQ93_TAKRU IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVV-TSPQTLSNLCLKINVKLGGINNIL
AGO3_DANRE IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNIL
I3K864_ORENI IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNIL
H2U5L9_TAKRU IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNIL
****************.*****************: ************************
AGO3_HUMAN VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
F7HXC6_CALJA VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
H2PYM8_PANTR VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
H2N805_PONAB VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
AGO3_MOUSE VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
AGO3_BOVIN VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
E2R0U1_CANLF VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAFVGSMDAHPSRYCATVRVQRPRQE
G3SR29_LOXAF VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
G1L0W7_AILME VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
H0X2D8_OTOGA VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
G1SQM3_RABIT VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
AGO3_CHICK VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
F6YI65_MONDO VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
F6ZVE5_ORNAN VPHQRRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
I3KHJ0_ORENI VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
H2SQ93_TAKRU VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
AGO3_DANRE VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
I3K864_ORENI VPHQR-PSVFQQPIIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPCRYCATVRVQRPRQE
H2U5L9_TAKRU VPHQR-PSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQE
***** *******:**********************.********.**************
AGO3_HUMAN IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
F7HXC6_CALJA IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
H2PYM8_PANTR IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
H2N805_PONAB IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
AGO3_MOUSE IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
AGO3_BOVIN IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
E2R0U1_CANLF IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
G3SR29_LOXAF IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
G1L0W7_AILME IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
H0X2D8_OTOGA IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
G1SQM3_RABIT IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
AGO3_CHICK IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
F6YI65_MONDO IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
F6ZVE5_ORNAN IIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
I3KHJ0_ORENI VIQDLASMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKE
H2SQ93_TAKRU VIQDLASMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKE
AGO3_DANRE VIQDLASMVRELLIQFYKSTHYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKE
I3K864_ORENI VIQDLASMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKE
H2U5L9_TAKRU VIQDLASMVRELLIQFYKSTRYKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKD
:*******************::*************************************:
AGO3_HUMAN YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
F7HXC6_CALJA YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
H2PYM8_PANTR YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
H2N805_PONAB YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
AGO3_MOUSE YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
AGO3_BOVIN YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
E2R0U1_CANLF YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
G3SR29_LOXAF YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
G1L0W7_AILME YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
H0X2D8_OTOGA YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
G1SQM3_RABIT YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
AGO3_CHICK YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
F6YI65_MONDO YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
F6ZVE5_ORNAN YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
I3KHJ0_ORENI YQPGITYIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
H2SQ93_TAKRU YQPGITYIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
AGO3_DANRE YQPGITYIVVQKRHHTRLFCADRAERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
I3K864_ORENI YQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
H2U5L9_TAKRU YQPGITYIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ
*********************** ************************************
AGO3_HUMAN GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
F7HXC6_CALJA GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
H2PYM8_PANTR GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
H2N805_PONAB GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
AGO3_MOUSE GTSRPSHYHVLWDDNFFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
AGO3_BOVIN GTSRPSHYHVLWDDNCFTADELQLLTYQPSAHTYVHCTRSVSIPAPAYYAHLVAFRARYH
E2R0U1_CANLF GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
G3SR29_LOXAF GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
G1L0W7_AILME GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
H0X2D8_OTOGA GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
G1SQM3_RABIT GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
AGO3_CHICK GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
F6YI65_MONDO GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
F6ZVE5_ORNAN GTSRPSHYHVLWDDNCFTADELQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
I3KHJ0_ORENI GTSRPSHYHVLWDDNCFTADEFQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
H2SQ93_TAKRU GTSRPSHYHVLWDDNCFTADEFQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
AGO3_DANRE GTSRPSHYYVLWDDNCFTADEFQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
I3K864_ORENI GTSRPSHYHVLWDDNCFTADDFQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
H2U5L9_TAKRU GTSRPSHYHVLWDDNCFTSDEFQLLTYQL-CHTYVRCTRSVSIPAPAYYAHLVAFRARYH
********:****** **:*::****** .****:************************
AGO3_HUMAN LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
F7HXC6_CALJA LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
H2PYM8_PANTR LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
H2N805_PONAB LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
AGO3_MOUSE LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
AGO3_BOVIN LVDKERDSAEGSHVSGQSNGRDPQALAKAAQIHQDTLRTMYFA
E2R0U1_CANLF LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
G3SR29_LOXAF LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
G1L0W7_AILME LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
H0X2D8_OTOGA LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
G1SQM3_RABIT LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
AGO3_CHICK LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
F6YI65_MONDO LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
F6ZVE5_ORNAN LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
I3KHJ0_ORENI LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA
H2SQ93_TAKRU LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA
AGO3_DANRE LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA
I3K864_ORENI LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA
H2U5L9_TAKRU LVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA
*****:***********************.***:*********