CLUSTAL format seed alignment for MF_03059
_____________________________________________________________________________
Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
RRF2M_ASPFN ---------------------------MVAAPLLRAHQAA------RLQSVSTSRLGLNP
RRF2M_ASPNC ---------------------------MVTALFLRASHQTVRPTGLRQCQAAASRLGCNA
RRF2M_EMENI ---------------------------MVSALLLRARQNG--RAARCLDYPKVKCWALAS
RRF2M_TALMQ ---------------------------MVTAPLLGWVAVRPIPRLSKLNTCKYVSSSLQS
RRF2M_TALSN ---------------------------MVSAPLLGWAAIRPIP-VSRLKTCKYASNSLQS
G2Y660_BOTF4 ------------------------------------------------------------
RRF2M_YARLI ------------------------------------------------------------
RRF2M_EREGS ---------------------MPWCNTRLRTCGASPKIFLRRVRCPVLLHNWTIGRV---
RRF2M_KLULA ------------------------------------------------------------
RRF2M_VANPO ------------------------------------------------------------
RRF2M_YEAST ---------------------------------------MWKWNVRRWAGARVNISK---
RRF2M_YEAS1 ---------------------------------------MWKWNVRRWAGARVNISK---
RRF2M_YEAS7 ---------------------------------------MWKWSVRRWAGARVNISK---
RRF2M_CANGA ------------------------------------------------------------
RRF2M_CANAL --------------------------------------MFCRKYV---------------
RRF2M_CANDC --------------------------------------MFCRKYA---------------
RRF2M_LODEL --------------------------------------MIVRNLLGKNRLCCLQPKLLLS
RRF2M_DEBHA --------------------------------MTNTGPIVRRVFRYASVLDTICYK----
RRF2M_PICST --------------------------------------MIIATSLRSQTFCTWRAW----
RRF2M_PICGU -------------------------------------MFSINARTKVPIWVPFIAR----
F4P6Y6_BATDJ MVVYLIKASTMHCSPFKVCALQSWLITRISSKSLSSVSCLAHTSTPWKTARSYPSEFSRP
RRF2M_SCHPO ------------------------------------------------------------
RRF2M_HUMAN ----------------------MLTNLRIFAMSHQTIPSV-YINNICCYKIRASLKRLKP
RRF2M_PONAB ----------------------MLTNLRIFAMSHQTIPSV-CINNICCYKIRASLKRLKP
RRF2M_BOVIN -----------------------MSNLRIFAVNQKKISSLHYFNNMCSSKIRASLKRLKL
RRF2M_MOUSE ----------------------MFTKWRIFAVNHQRTFSV-HLNTMCYCKIKANLKRLKT
RRF2M_RAT ----------------------MFTNWRIFAVNRQKTFSV-HIHTTCYCKIKANLKRSKT
RRF2M_DANRE -----------------------MLLSLTFPVLRGCTGHL----------VNRSLQAPRW
RRF2M_ANOGA -------------------------------------------------MLCNRLHKAAF
RRF2M_CULQU ----------------------------------------------MLLLLCNR-SVVPR
RRF2M_DROME ------------------------------------------------MLKYAWQSGPKQ
RRF2M_DROYA ------------------------------------------------MLRCAWQNGPRQ
RRF2M_DROER ------------------------------------------------MLKCAWQNGPRQ
RRF2M_DROAN ------------------------------------------------MLKYEFLHGLQK
RRF2M_DROPE ------------------------------------------------MLKYALHSGGMP
RRF2M_DROPS ------------------------------------------------MLKYALHSGGMP
RRF2M_DROWI ------------------------------------------------MLRYVYFNGFGM
RRF2M_DROGR ------------------------------------------------MLQYCLL----R
RRF2M_ASPFN HVIKSAGRLQLLRGSSFSTATSKWQAGV-LDRTRNIGIIAHIDAGKTTTTERMLYYSGFT
RRF2M_ASPNC SLIPGVKKGQFPKIQMLSTSASKLQADT-LDRTRNIGIIAHIDAGKTTTTERMLYYSGFT
RRF2M_EMENI LPKSSLEKPGFSQVRRFSVFHPQSQVN--LDLTRNIGIIAHIDAGKTTTTERMLYYSGLT
RRF2M_TALMQ YKRSVGSCLGKQQSRDFSYSATLTDAGINLEKTRNIGIIAHIDAGKTTTTERMLYYSGFT
RRF2M_TALSN YNGIVASYLRLHYYRSLSSSAVLAEAIVHLEKTRNIGIIAHIDAGKTTTTERMLYYSGFT
G2Y660_BOTF4 ----MAKPSQLNAFIRYSSQQTESHDTL-TETTRNIGIIAHIDAGKTTTTERMLYYSGYT
RRF2M_YARLI -----------MASRHYSAKNT-------TKKIRNIGIIAHIDAGKTTTTERILYLSGTI
RRF2M_EREGS ----------SSVSKMILRFLRSYSKRVDITRVRNIGIIAHIDAGKTTTTERMLYYSGKI
RRF2M_KLULA ----------MQHTMSFRIFLRRYATKHDLSKVRNIGIIAHIDAGKTTTTERMLYYSGKI
RRF2M_VANPO ------------MFGFGIRQLRGYASKTDLSKIRNIGIIAHIDAGKTTTTERMLYYSGKT
RRF2M_YEAST ----------NRLSVINVGSRYLSTARSPLSKVRNIGIIAHIDAGKTTTTERMLYYAGIS
RRF2M_YEAS1 ----------NRLSVINVGSRYLSTARSPLSKVRNIGIIAHIDAGKTTTTERMLYYAGIS
RRF2M_YEAS7 ----------NRLSVINVGSRYLSTARSPLSKVRNIGIIAHIDAGKTTTTERMLYYAGIS
RRF2M_CANGA ----------MLRFVCGRFQSGIRRYATTIDRFRNIGIIAHIDAGKTTTTERMLYCAGKI
RRF2M_CANAL -----------FQTWKQLSRSYSTVNSIGAAKTRNIGIIAHIDAGKTTTTERMIYYSGRT
RRF2M_CANDC -----------FQTWKQFSRFYSAVNNIRASKTRNIGIIAHIDAGKTTTTERMIYYSGKI
RRF2M_LODEL TLSQRPQLQLSLQLLCRATRLYATVNDIALPKTRNIGIIAHIDAGKTTTTERMIYYSGKS
RRF2M_DEBHA ----------RGIHSSRALLSESRLNSVPPDRTRNIGIIAHIDAGKTTTTERMLFYSGKT
RRF2M_PICST ----------RAVHSTAVRL-ESKLNEVPIDRTRNIGIIAHIDAGKTTTTERMLYYSGKT
RRF2M_PICGU ----------KGFSMSTRQLAEPKLNQVSSLNTRNIGIIAHIDAGKTTTTERMLFYSGKT
F4P6Y6_BATDJ CPTRIHLKNTNSCLFSASAHSQHSSATIDPQFIRNLGIIAHIDAGKTTTTERMLYYVGYT
RRF2M_SCHPO -----MLRIVWKPLKIRLPVWRRYQSNISINSIRNVGIIAHIDAGKTTLTEKMLYYGGFT
RRF2M_HUMAN HVPLGRNCSSLPGLIGNDIKSLHSIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYT
RRF2M_PONAB HVPLGRNCSSLPGLIGNDIKSLHSIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYT
RRF2M_BOVIN HVLLGRNYSSLPGLIGNDIKSLHSIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYT
RRF2M_MOUSE QLPLTRNYSSAPGIAGSDVKSLHSVINPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYT
RRF2M_RAT QVPLTRSYSSPPGIVGNEVKSLHSIINPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYT
RRF2M_DANRE RVTWKRSYS----LLQDEVKSLRTVVNPDISKIRNIGIMAHIDAGKTTTTERMLYYSGYT
RRF2M_ANOGA AARLRPRLPATVASCRQVHN---SDGTISEKRIRNIGILAHIDAGKTTTTERMLYYSGRT
RRF2M_CULQU GIRRILRTAATVTSLRWNHTGPSASETLLEKNIRNIGILAHIDGGKTTTTERMLFYAGKT
RRF2M_DROME SNRWLWHLSNQIWKRSYSSK------------IRNIGILAHIDAGKTTTTERMLFYAGKT
RRF2M_DROYA SNRWLRHLSNQIWKRSYSSK------------IRNIGILAHIDAGKTTTTERMLFYAGKT
RRF2M_DROER SNRWLWQLSNQIWKRSYSSK------------IRNIGILAHIDAGKTTTTERMLFYAGKT
RRF2M_DROAN RSHYLRQLSGQFFSRSYSSK------------IRNIGILAHIDAGKTTTTERMLFYAGKT
RRF2M_DROPE RNRLLRQLSAYIFRRSYSSN------------IRNIGILAHIDAGKTTTTERMLFYSGKT
RRF2M_DROPS RNRLLRQLSAHIFRRSYSSN------------IRNIGILAHIDAGKTTTTERMLFYSGKT
RRF2M_DROWI RQGLLKRCSSHILRRSYSSD------------IRNIGILAHIDAGKTTTTERMLFYAGKT
RRF2M_DROGR RYRFLLRQHAQVIKRCYSGD------------IRNIGILAHIDAGKTTTTERMLFYAGKT
**:**:****.**** **:::: *
RRF2M_ASPFN RRIGDVDEGSTVTDFLPAERARGITIQSAAITFHWPPQTAGDGNTTP-----QEPQTPRS
RRF2M_ASPNC RRIGDVDEGSTVTDFLPAERARGITIQSAAITFHWPPQAA--------------------
RRF2M_EMENI RRIGDVDEGSTVTDFLPAERARGITIQSAAITFHWPPAECGNATR-------QDPRSPRS
RRF2M_TALMQ RRIGDVDDGSTVTDFLPAERARGITIQSAAITFHWPPLAADGTSSGPSLEELESQNLPRS
RRF2M_TALSN RRIGDVDDGSTVTDFLPAERARGITIQSAAITFHWPPLTGDGTSSSPSLEDLEAQNLPRS
G2Y660_BOTF4 RRIGDVDDGSTVTDFLPAERARGITIQSAAVTMHWPPVTEKAASS-------KASDPSRS
RRF2M_YARLI KHLGNVDEGDTTMDFLPAERERGITIASAATSFNWN------------------------
RRF2M_EREGS KRIGDVDHGDTITDFLPQERSRGITIQSAAISFNWRDNYT--------------------
RRF2M_KLULA NRIGDVDQGDTITDYLPQERSRGITIQSAAISFNWKKDYK--------------------
RRF2M_VANPO NRIGNVDQGDTVTDYLPQERSRGITIQSAAISFNWQNDHR--------------------
RRF2M_YEAST KHIGDVDTGDTITDFLEQERSRGITIQSAAISFPWRNTFA--------------------
RRF2M_YEAS1 KHIGDVDTGDTITDFLEQERSRGITIQSAAISFPWRNTFA--------------------
RRF2M_YEAS7 KHIGDVDTGDTITDFLEQERSRGITIQSAAISFPWRNTFA--------------------
RRF2M_CANGA KRIGDVDSGDTVTDFLPQERDRGITIQSAAISFQWHDSSRDNSPR---------------
RRF2M_CANAL KRIGNVDEGDTVTDYLPSERERGITIQSAAITLPWNQHK---------------------
RRF2M_CANDC KRIGNVDEGDTVTDYLPSERERGITIQSAAITLPWNQHK---------------------
RRF2M_LODEL KRIGNVDEGDTVTDYLQAERERGITIQLAAITIPWNNHK---------------------
RRF2M_DEBHA RRIGNVDEGDTVTDYLPSERERGITIQSAAITIPWNKNK---------------------
RRF2M_PICST KRIGNVDEGDTVTDYLPSERQRGITIQSAAISIPWNNHK---------------------
RRF2M_PICGU TTMGDVDQGDTVTDYLPSERSRGITIQSAAITIPWNNNK---------------------
F4P6Y6_BATDJ KRLGNVDEGSTVTDYLKTEKERGITIQSACIPLAWKNHR---------------------
RRF2M_SCHPO SHFGNVDTGDTVMDYLPAERQRGITINSAAISFTWRNQR---------------------
RRF2M_HUMAN RSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDWKGYR---------------------
RRF2M_PONAB RSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDWKGYR---------------------
RRF2M_BOVIN RSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDWKGYR---------------------
RRF2M_MOUSE RSLGDVDDGDTVTDFMAQERERGITIQSAAVTLDWKGYR---------------------
RRF2M_RAT RSLGDVDDGDTVTDFMAQERERGITIQSAAVTLDWKGYR---------------------
RRF2M_DANRE RALGDVDDGDTVTDYMAQERERGITIQSAAVTFDWKDYR---------------------
RRF2M_ANOGA DMLGEVKLGNTVTDFLQQERERGITICSAAVSFNWKEYR---------------------
RRF2M_CULQU NVLGEVHHGNTVTDFLVQERERGITICSAAVSFDWRDHR---------------------
RRF2M_DROME RALGEVHRGNTVTDYLTQERERGITICSSAVTFSWNDHR---------------------
RRF2M_DROYA RALGEVHRGNTVTDYLTQERERGITICSSAVTFPWNDHR---------------------
RRF2M_DROER RALGEVHRGNTVTDYLTQERERGITICSSAVTFPWNDHR---------------------
RRF2M_DROAN RTLGEVHRGNTVTDYLTQERERGITICSSAVTFAWNGHR---------------------
RRF2M_DROPE RSLGEVHRGNTVTDYLTQERERGITICSSAVTFPWSGNR---------------------
RRF2M_DROPS RSLGEVHRGNTVTDYLTQERERGITICSSAVTFPWRGNR---------------------
RRF2M_DROWI RSLGEVHRGNTVTDYLTQERERGITICSSAVTFPWNGKR---------------------
RRF2M_DROGR RSLGEVHRGNTVTDYLAQERERGITICSSAVTFNWNGKR---------------------
:*:*. *.* *:: *: ***** :. .: *
RRF2M_ASPFN ASSHTVNLIDTPGHADFTFEVMRSLRILDGAVCILDGVAGVEAQTEQVWHQASTYRIPRI
RRF2M_ASPNC -----VNLIDTPGHADFTFEVMRSLRILDGAVCILDGVAGVEAQTERVWHQASTYRIPRI
RRF2M_EMENI ASSHMVNLIDTPGHADFTFEVLRSLRILDGAVCILDGVAGVEAQTEQVWHQASTYNIPRI
RRF2M_TALMQ RASHTVNLIDTPGHADFTFEVLRSLRILDGAVCILDGVAGVEAQTEKVWHQASVYQIPRV
RRF2M_TALSN RASHTVNLIDTPGHADFTFEVLRSLRILDGAVCILDGVAGVEAQTEKVWHQASVYQIPRI
G2Y660_BOTF4 LISHTLNLIDTPGHADFTFEVLRSLRILDGAVCILDGVAGVEAQTEKVWKQANNYSIPRI
RRF2M_YARLI --NHTVNLIDTPGHADFTFEVIRSIRVLDGAVCILDGVAGVEAQTEKVWKQASEMGIPKI
RRF2M_EREGS -----VNLIDTPGHADFTFEVIRSLRVLDGCVTILDAVAGVEAQTEKVWKQAAEI--PKV
RRF2M_KLULA -----INLIDTPGHADFTFEVIRSLKVLDSCVTILDSVAGVEAQTEKVWKQSSGL--PKI
RRF2M_VANPO -----INLIDTPGHVDFTFEVIKSLKVLDGCVTILDAVAGVEAQTEKVWKQSYGI--PKI
RRF2M_YEAST -----INLIDTPGHIDFTFEVIRALKVIDSCVVILDAVAGVEAQTEKVWKQSKSK--PKI
RRF2M_YEAS1 -----INLIDTPGHIDFTFEVIRALKVIDSCVVILDAVAGVEAQTEKVWKQSKSK--PKI
RRF2M_YEAS7 -----INLIDTPGHIDFTFEVIRALKVIDSCVVILDAVAGVEAQTEKVWKQSKSK--PKI
RRF2M_CANGA ----VINLIDTPGHADFIFEVIRSLKVLDGAVLILDGVAGVEAQTEKLWRYSRNI--PKI
RRF2M_CANAL -----INIIDTPGHADFTFEVIRSLRVLDGAVTILDAVAGVEAQTEKVWKQASALNLPKV
RRF2M_CANDC -----INIIDTPGHADFTFEVIRSLRVLDGAVTILDAVAGVEAQTEKVWKQASSLNLPKI
RRF2M_LODEL -----INIIDTPGHADFTFEVIRSLRVLDGAVTILDAVAGVEAQTEKVWKQASALKLPRM
RRF2M_DEBHA -----INIIDTPGHADFTFEVTRSLRVLDSCVTILDAVAGVEAQTEKVWKQAQALGIPKI
RRF2M_PICST -----INIIDTPGHADFTFEVTRSLRVLDGAVTILDGVAGVEAQTEKVWKQATSLNIPKI
RRF2M_PICGU -----INIIDTPGHADFTFEVIRSLRVLDGCVTILDAVAGVEAQTEKVWKQAQALKIPRI
F4P6Y6_BATDJ -----LNLIDTPGHVDFTIEVERSLRVLDGAVCVLDGVAGVEAQTETVWAQSNRYSIPRI
RRF2M_SCHPO -----INLIDTPGHADFTFEVERSVAVLDGAVAIIDGSAGVEAQTKVVWKQATKRGIPKV
RRF2M_HUMAN -----VNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI
RRF2M_PONAB -----VNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI
RRF2M_BOVIN -----INLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHKVPRI
RRF2M_MOUSE -----VNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHKIPRI
RRF2M_RAT -----VNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHKIPRI
RRF2M_DANRE -----INLIDTPGHVDFTLEVERALRVLDGAVAVFDASAGVEAQTMTVWRQAEKHQIPCV
RRF2M_ANOGA -----INLLDTPGHIDFTMEVEQSLGAVDGTVIILDGSAGVEAQTVTVWGQADRHRLPRL
RRF2M_CULQU -----VNLLDTPGHIDFTMEVEQSLAAVDGTVVILDGSAGVEAQTVTVWSQADRHRLPRL
RRF2M_DROME -----INLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWSQADKHKLPRL
RRF2M_DROYA -----INLLDTPGHIDFTMEVEQSLFAVDGVVVVLDGTAGVEAQTVTVWSQADKHKLPRL
RRF2M_DROER -----INLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWSQADKHKLPRL
RRF2M_DROAN -----INLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWTQADKHKLPRL
RRF2M_DROPE -----INLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWTQADKHKLPRL
RRF2M_DROPS -----INLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWTQADKHKLPRL
RRF2M_DROWI -----INLLDTPGHIDFTMEVEQSLHAVDGVIVVLDATAGVEAQTMTVWSQADKHRLPRL
RRF2M_DROGR -----INLLDTPGHIDFTMEVEQSLYAVDGVIVVLDGTAGVEAQTVTVWTQADKHKLPRL
:*::***** ** :** :.: :*. : ::*. ******* :* : * :
RRF2M_ASPFN VYVNKLDRDGAAFGRTVREVASRL----GGWPAVCQIPWFE----------GGNGRFTGI
RRF2M_ASPNC VYINKLDRDGAAFGRTVREISSRL----AGYPAVCQVPWFE----------GGNGRFVGV
RRF2M_EMENI VYVNKMDRDGAAFGRTVREVASRL----GGWPAVCQIPWFE----------GGDGRFVGV
RRF2M_TALMQ VYVNKLDRDGAAFGRTVREVGSRL----QGWPAVCQIPWFE----------GGNGRFTGI
RRF2M_TALSN VYVNKLDRDGAAFGRTVREVGSRL----QGWPAVCQIPWFE----------GSNGRFTGI
G2Y660_BOTF4 AFVNKLDREGAAFARTVKEIASRL----RGWPAVCQIPWWE----------GGKGKFTGV
RRF2M_YARLI AFVNKMDRAGAGFGRTVKEIVSKL----RTRVALLTVPVFSK---------SSDQVFEGV
RRF2M_EREGS CFINKMDRVGAGYSRAVKELIVKL----KTRVLLLNTPLFAAR------DSSADPVFVGV
RRF2M_KLULA CFLNKMDRVGAGFSRTVKELVVKM----NTRALLINTPIFQVD------PVTNESKFSGV
RRF2M_VANPO CYINKMDRVGSGYSRTVKELMIKM----NQRVVLANMPLFKLD------PVTNEQVFEGV
RRF2M_YEAST CFINKMDRMGASFNHTVNDLINKFMRGTTTKPVLVNIPYYRKQ------PTSNDYVFQGV
RRF2M_YEAS1 CFINKMDRMGASFNHTVNDLINKFMRGTTTKPVLVNIPYYRKQ------PTSNDYVFQGV
RRF2M_YEAS7 CFINKMDRMGASFNHTVNDLINKFMRGTTTKPVLVNIPYYRKQ------PTSNDYVFQGV
RRF2M_CANGA CFVNKMDRVGAGFSKTLKELTYKT----DRRCVVVNFPYFEQT------NQSEDPVFCGV
RRF2M_CANAL VYVNKMDRPGAGFSRTVQEVIQKL----ETRVVLCNLPYFET-------NKESDLEFKGV
RRF2M_CANDC VYVNKMDRPGAGFSRTVQEVIQKL----ETRVVLCNLPYFET-------NKESDLEFKGV
RRF2M_LODEL IYVNKMDRPGAGFSRTVKEVIQKL----ETRVVLCNTPFFE--------NQELNPEFRGV
RRF2M_DEBHA AYVNKMDRDGAGFSRTVKEIIQKL----QTRVVLCNIPYWET-------PVNDVPIFKGV
RRF2M_PICST AYVNKMDRPGAGFSRTVMEIIEKL----QTRVVLCNVPYFEN-------SKDNDPVFCGV
RRF2M_PICGU AFVNKMDRPGAGFSRTVKEVVQKL----QTKVVLCNIPYFEM-------SKDD-AVFVGV
F4P6Y6_BATDJ AFVNKLDRDGASFKNTVHAMSKRL--GGWGKPAIIQLPIFRNGHGVLVTDSHGGGKLEGI
RRF2M_SCHPO IFVNKMDRVGSSLGSTIRSIYTNL---DCPYPLVLQLPVYSDGLQ--------ERKFLGI
RRF2M_HUMAN CFLNKMDKTGASFKYAVESIREKL----KAKPLLLQLPIGEAK------------TFKGV
RRF2M_PONAB CFLNKMDKTGASFKYAVESIREKL----KAKPLLLQLPIGEAK------------TFKGV
RRF2M_BOVIN CFLNKMDKIGASFNYAVESIREKL----KAKPLLLQLPIGEGK------------AFKGV
RRF2M_MOUSE CFLNKMDKTGASFNYAVESIREKL----KAKPLILQLPIGEAR------------TFQGV
RRF2M_RAT CFLNKMDKTGASFNYAVESIREKL----KAKPLILQLPIGEAR------------TFQGV
RRF2M_DANRE CFLNKMDKPAASLRYSLDSIKAKL----KANPVLLQIPIGSGK------------SFTGL
RRF2M_ANOGA VFVNKMDKESADFDACLEDLEKKL----STVPVPLQMPIKEAG------------KLVGV
RRF2M_CULQU VFVNKMDKESADFEGCLEELEKKL----GVVAVPLQMPVIKEG------------KLTGV
RRF2M_DROME IFVNKMDRPDADFEKCVSDLKDKL----ETQPVCLQYPVKNED------------GVLAI
RRF2M_DROYA IFVNKMDRPDADFDKCVADLKDKL----ETQPVCLQYPVKNED------------GVLAI
RRF2M_DROER IFVNKMDRPDADFVKCVSDLKDKL----ETQPVCLQYPVKNED------------GQLAI
RRF2M_DROAN IFVNKMDRPDADFEKCIADLKEKL----EAHPVCLQYPVKNED------------GVLAI
RRF2M_DROPE AFVNKMDRPDADFDKCVNDLRTKL----ETQPVCIQYPSKNQD------------GLLAI
RRF2M_DROPS AFVNKMDRPDADFDKCVNDLRTKL----ETQPVCIQYPSKNQD------------GLLTI
RRF2M_DROWI VFVNKMDRPDADFNKCVEDLKSKL----ETFPVCIQYPAKSNE------------GQLGI
RRF2M_DROGR VFVNKMDRPDANFEKCIVDLTEKL----DAKPICTQYPTKSAD------------GQLGI
::**:*: : : : . * :
RRF2M_ASPFN ADAINLQGLRWE--EG-DGKSVKMFNLEQLASEEPQLAQELKRARVALVELLSEHDEAMV
RRF2M_ASPNC GDAINLQGLRWQ--DG-DGKAVKMFNLQELDGEEPGLAQEIKRARTALVELLSEHDETMI
RRF2M_EMENI ADAINLQGLLWS--GG-DGKSVKRFSLSELDEAESQLAQELRRARVALVELLSEHDEIIV
RRF2M_TALMQ ADVISLQGLLWK--EGGDGKSVKVFDLAGLENEDKRLAEELKHARVALVELLSEHDEDMV
RRF2M_TALSN ADVVSLQGLLWK--EGGDGKSVKVFDLNGLENEDKSLAEELKRARVALVELLSEHDEDMV
G2Y660_BOTF4 GDAVNLCALKWE--EGGDGKSIQHFTLDQLRKDNPEFSEEIIKARAALVEALCEFDDGLL
RRF2M_YARLI VDILNGCVITWT--TGGDGKQTVVVPVSEASAE---VQEEYQKARTALVETLTELDEELV
RRF2M_EREGS LDAVNGQLLEWD-PED--PDKISAKAVDK----ECAHYEELVSAREALVETLSEVDEKLV
RRF2M_KLULA LDLIYGKQLIWD-TND--PDKINVTDVDE----NHDCYEYLVRGREALVETLGETDESIV
RRF2M_VANPO LDVVNMKALRWD-STD--VNKVDIADIDKF---DSSLLDELTKAREAMVETLSEFDENLV
RRF2M_YEAST IDVVNGKRLTWN-PEN--PDEIIVDELDG------TSLEQCNRCRESMIETLTEYDEDLV
RRF2M_YEAS1 IDVVNGKRLTWN-PEN--PDEIIVDELDG------TSLEQCNRCRESMIETLTEYDEDLV
RRF2M_YEAS7 IDVVNGKRLTWN-PEN--PDEIIVDELDG------TSLEQCNRCRESMIETLTEYDEDLV
RRF2M_CANGA IDVINMKLLKWD-TKANSPDAVTVVDLLEL-NDSDNAKVEAIKSRESMVEILGELDDVFV
RRF2M_CANAL IDVIHQKLLKWN-ETDANGNEISVVNID---ETTPDLLQILEKSRESMVETLGEYDERII
RRF2M_CANDC IDVIHQKLLKWN-EMDANGNEISVVDID---KTTPELLQILEKSRESMVETLGEYDERII
RRF2M_LODEL IDVIHGKLLKWK-EADEFGKEIDVEDID---ETKPELYDVYCKAREYMVETLGEYDESII
RRF2M_DEBHA LDVLNKKLLKWNSDSNANGTDISVTDLEKEMDKYPELYEMVSKSRESMVETLGEFDETII
RRF2M_PICST ADILHVKLLKWNPEIDPHGKNITVIDIEAERDTYPEVYETVVKSRESMVETLGEFDEAII
RRF2M_PICGU IDILHNKILKWNIDEDPNGRDITVIDLQEAKESHQEAYMEALKCRESMVETLGGIEETVV
F4P6Y6_BATDJ VDLLTMERLDWFKDPS-SGGVVTRSQLTLGEKEWALVYEDAVKYRNMLIETLSEMDDGIV
RRF2M_SCHPO LDILQQKMILWDTSDNKLGTDGTHVQELPI---PESHMERFIEARNALVMSLCDVDETLC
RRF2M_HUMAN VDVVMKEKLLWNCN---SNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFA
RRF2M_PONAB VDVVTKEKLLWNCN---SNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFA
RRF2M_BOVIN VDVVRTEKLLWNPN---SDDGKDFERKPLLEMSDPKLLKETTEARNALIEQVADLDDEFA
RRF2M_MOUSE VDVVNKEKLLWNSN---SDDGKDFERMPLSEASDRELLKETIEARNSLIEQVADLDDEFA
RRF2M_RAT VDVVNREKLIWNSD---SDDGKDFERKPLSEASDPTLLKETVEARNSLIEQVADLDDEFA
RRF2M_DANRE VDLITRQKMMWQGNAL-TNDGRSFEINSLQPSDDPNVLLAVSEARAALIEQVADLDDDFA
RRF2M_ANOGA IDVLSASQIIWDSK----GKGRSYKAIPIS---DEQLHDQVQEKLYELIDLLSGMDDNLA
RRF2M_CULQU VDVLSGAQVVWDKQ----NHGRTYKAIPLV---DQQLVE-AQDKLYQIIDVLSGMDDGLA
RRF2M_DROME NDVITLERLSWQQK----DLGRSYRNVKLE---PSDDLRLLQEKRNELIDQLSGLDDELA
RRF2M_DROYA NDVITLERLSWHQK----DLGRSYKNVKLE---PSDDLRQLQEKRSELIDQLSGLDDELA
RRF2M_DROER NDVIHLERLSWQQK----DLGRSYKNVKLE---PSDDLRQLQEKRNELIDQLSGLDDELA
RRF2M_DROAN NDVITLERLTWQQK----DLGQKYIRMKLE---PSDELRDLQEKRNELIDRLSGVDDELA
RRF2M_DROPE NDVITLEQLTWQPK----DLGRSYSKTKLE---PSDDLRQLQEKRNELIDQLSGLDDELA
RRF2M_DROPS NDVITLEQLTWQPK----DLGRSYSKTKLE---PSDDLRQLQEKRNELIDQLSGLDDELA
RRF2M_DROWI YDVITLEQLNWQQK----DLGRSYSKLKLE---PSDGLRQLQDKRNELIDQLSGLDDELA
RRF2M_DROGR FDVITMEQMTWQQN----DLGRNYSKVKLE---SST---ELQEKRNELIDQLSGLDDELA
* : : * :: : :: .
RRF2M_ASPFN EKFFDC--EEDHLAVPPNDILESLRRCLLEEQGRKIIPIFAGASFRNIGVQPLLDAVTNL
RRF2M_ASPNC EKFFEH--DEDHLAVPPNDILDSLRRCLLQEQGRKIIPIFAGASFRNIGVQPLLDAVTNL
RRF2M_EMENI EKFFEN--EEDHLSVSPADILDSLRRCLLEGNGRKIIPIFAGASFRNIGVQPLLDSVVDL
RRF2M_TALMQ ESFFEH--E-DHLKVPPMTILKSLRKCLLGPEAQKIIPVFAGSSFRNMGVQPLLDAVNNL
RRF2M_TALSN ESFFEH--EEDHLTVPSITILKSLRKCLLGPETQKIIPVFAGSSFRNMGVQPLLDAVNNL
G2Y660_BOTF4 ETWLEC--NDDSLLISSADITKSLRKCVLDGSG-KLIPVFAGASFRNIGVQPLLDAINNL
RRF2M_YARLI EKFLES--E-DYMQITTEDIKRALRTATI---NNDIVPVLCGASFRNIGVQPLMDAVVDF
RRF2M_EREGS EYFLGE-ADGDYMKVPVEVLNESIRRATL---SQYAVPVLCGASFKNIGVQPLLDAVVDY
RRF2M_KLULA EHFFND-ADGEYLNVSPEVLNASIRKATI---SLSATPVLCGASFRNIGVQPLLDAIANY
RRF2M_VANPO EHFLED-AEGDYLKVSPTILNSSIRKSTL---SQDITPILCGSSFRNIGVQPLLDAVVNY
RRF2M_YEAST QHFLEE-AEGDYSKVSAQFLNASIRKLTM---KNMIVPVLCGASFKNIGVQPLLDAIVNY
RRF2M_YEAS1 QHFLEE-AEGDYSKVSAQFLNASIRKLTM---KNMIVPVLCGASFKNIGVQPLLDAIVNY
RRF2M_YEAS7 QHFLEE-AEGDYSKVSAQFLNASIRKLTM---KNMIVPVLCGASFKNIGVQPLLDAIVNY
RRF2M_CANGA QEFFDGPSEGNSLKVSAQVLNKSIRKLTI---ANELTPVLAGASFKNVGIQPLLDGIIQY
RRF2M_CANAL DSFLEH--DENYLKIPPMLLDQVIRKATI---DNYLTPVFCGASFRNIGVQPLMDGITKY
RRF2M_CANDC DSFLEH--DENYLKIPPILLDQVIRKATI---DNYLTPVFCGASFRNIGVQPLMDGITKY
RRF2M_LODEL DAFLEN--DENYLKISPELLNRAIRKATI---DNYLVPVFCGASFRNIGVQPLMDGITNY
RRF2M_DEBHA DSFLEN--DEDYMKIPVAVLNSAIKRGTL---ANYVTPVFCGSSFRNIGVQPLMDAVVNF
RRF2M_PICST DSFLES--NEDYMNIPINVLNEAIRKATL---ENYLTPVYCGSSFRNIGVQPLMDGVVKY
RRF2M_PICGU DAFLEC--DEDYMKIPSSILKSAIRKACI---SNQVTPVFCGSAFRKIAVQPLLDGVVDY
F4P6Y6_BATDJ NVFLEC--DGDHAQVPAKEIQNACRRATI---SGQAVPVLCGASFRNIGVQPILDAIVNY
RRF2M_SCHPO DEYLEN---EDSLAFTNDRLFKIIKQKTI---SGNVVPVLCGSSLKNIAVQPIMDAIIDY
RRF2M_HUMAN DLVLEE-FSENFDLLPAEKLQTAIHRVTL---AQTAVPVLCGSALKNKGIQPLLDAVTMY
RRF2M_PONAB DLVLEE-FSENFDLLPAEKLQTAIHRVTL---AQTAVPVLCGSALKNKGIQPLLDAVTMY
RRF2M_BOVIN DLVLGE-FSENFDLLPAEKLQTAIHRVTL---AQTAVPVLCGSALKNKGVQPLLDAITMY
RRF2M_MOUSE DLVLGE-FSENFDLVPAEKLQAAVHRVTL---AQAAVPVLCGSALKNKGVQPLLDAVTTY
RRF2M_RAT DLVLGE-FSEDFDLVPAEKLQAAIHRVTL---AQAAVPVLCGSALKNKGVQPLLDAVTTY
RRF2M_DANRE ELLLGE-YGENFDAVPAVKLQEAVRRVTL---ARKGVPVLCGSSLKNKGVQPLLDAITAY
RRF2M_ANOGA QAIIE---ANSLENVKLNLVLDALRNCTL---KQQIVPVLLGSSYKNVGVQLLMDSVLNF
RRF2M_CULQU QVIIE---SDSMDNVKPELVASAIRACTM---KQQIVPVFLGSAYKNIGVQLLMDAVLKY
RRF2M_DROME DVVIS---TESFDNVDNALIERALRRATT---QQKVVPVLLGSAYKNVGIQRLMDAVNAY
RRF2M_DROYA DVVIS---TESFDKVDNALIERALRRATT---QQKVVPVLLGSAYKNVGIQRLMDAVNSY
RRF2M_DROER DVVIS---TESFDKVDNALIERALRRATT---QQKVVPVLLGSAYKNVGIQRLMDAVNSY
RRF2M_DROAN DVVIS---TESFDKVDNHLIERALRRATG---QLKVVPVLLGSAYKNVGIQRLMDAVNSY
RRF2M_DROPE DVVIS---TESFDNVSNALIERALRRATC---QQKVVPVLLGSAYKNVGIQRLMDAVNTY
RRF2M_DROPS DVVIS---TESFDNVSNALIERALRRATC---QQKVVPVLLGSAYKNVGIQRLMDAVNTY
RRF2M_DROWI DVVIS---TESFDKVSNELVNKALRRVIC---QQKAVPVLLGSAYKNIGIQCLMDAVNHY
RRF2M_DROGR DVVIS---TESFDKVSNELIGQALRRATC---QQKVVPVLLGSAYKNIGIQPLMDAVNAY
: : . . : : *: *:: :: .:* ::*.:
RRF2M_ASPFN LPSPPETPEPEVSIGGVKGGLRRLLSGDLLVEQGEKAASA-KGKHKKKSAIQAES---RN
RRF2M_ASPNC LPSPLETPDAE-----------------------------------KKSVTQAES---QN
RRF2M_EMENI LPSPQETPDPEVAIGGVKGSLRRLLSGDLLVEQKEKAAP--KGKQKKKAAVVADS---RN
RRF2M_TALMQ LPGPSESVDPEISLGNSKGSLGNLLSGELTLQQEPKTANIAKPKQKKKTAVAPTSVDTKH
RRF2M_TALSN LPGPSESHDPEISLGSDKTSLGNLLSGELALQQDPKTASIEKSKQKKKAVVTRTSVDIKS
G2Y660_BOTF4 LPNPTERPEPEVRLGNVHGSLSQLLDGKLDLSAA------------QPRHLSKKSNARTS
RRF2M_YARLI LPSPAERPPTDALIAKSYTG-------------------------GKKSKVIPERAITLD
RRF2M_EREGS LPSPAEARLPELSNKDLPVQHH----------------------LKNGLLVNKNA-----
RRF2M_KLULA LPSPSEARPPELNHKNVPITQN----------------------PLTGLVLNKNP-----
RRF2M_VANPO LPSPLEAKFPEL-NEDIPISYD----------------------KRKGLLFDNNS-----
RRF2M_YEAST LPSPIEAELPELNDKTVPMKYD----------------------PKVGCLVNNNK-----
RRF2M_YEAS1 LPSPIEAELPELNDKTVPMKYD----------------------PKVGCLVNNNK-----
RRF2M_YEAS7 LPSPIEAELPELNDKTVPMKYD----------------------PKVGCLVNNNK-----
RRF2M_CANGA LPSPLEARLPEVNPKDIPVVHD----------------------PKVGALINKQN-----
RRF2M_CANAL LPSPLETSLPQITKNGKDVTKKVDGE--------------------KGLVVANDN-----
RRF2M_CANDC LPSPLETSLPEITKNGKEVPKKADDE--------------------KGLVVANDN-----
RRF2M_LODEL LPSPLETPVPDIKSKKKQEISAKMAN--------------------NGLIINNDP-----
RRF2M_DEBHA LPSPLETKVPDISSNAPKALAKMKGKNRKKKVTSEPTDVPLSMDPKHGLVINKNP-----
RRF2M_PICST LPSPLQISVPEITSSATKNVKIKHVK--AKQAVKQDMEVTTKMNNRTGLVVNANP-----
RRF2M_PICGU LPSPLQTPVPEITASTSKVSKKQKQK-----KNSKVSSVPIEMNPKKGLIVNKNP-----
F4P6Y6_BATDJ LPSPMDAPSAIATLSNGS----------------------------QQHILLKDP-----
RRF2M_SCHPO LPSPVEFYEKNASKETSS-----------------------------DKIISLDK-----
RRF2M_HUMAN LPSPEERNYEFL------------------------------------------------
RRF2M_PONAB LPSPEECNCEFL------------------------------------------------
RRF2M_BOVIN LPSPEERNYEFL------------------------------------------------
RRF2M_MOUSE LPSPEEREDRFL------------------------------------------------
RRF2M_RAT LPSPEEREHGFL------------------------------------------------
RRF2M_DANRE LPAPNERNHDLV------------------------------------------------
RRF2M_ANOGA LPAPSERNQIYDLTNSQARIEGDFIN---------------------------------V
RRF2M_CULQU LPAPNERNEIYN------------------------------------------------
RRF2M_DROME LPAPEERNQIYD------------------------------------------------
RRF2M_DROYA LPAPEERNQIYD------------------------------------------------
RRF2M_DROER LPAPEERNQIYD------------------------------------------------
RRF2M_DROAN LPAPEERNQIYD------------------------------------------------
RRF2M_DROPE LPAPEERNQIYD------------------------------------------------
RRF2M_DROPS LPAPEERNQIYD------------------------------------------------
RRF2M_DROWI LPAPEERNEIYN------------------------------------------------
RRF2M_DROGR LPMPEERNQMYD------------------------------------------------
** * :
RRF2M_ASPFN AIEKLQGCALAFKVVNDPKRGVLVYVRVYSGSLDR---------NSILYNTNLNVSERAP
RRF2M_ASPNC AIEKLQSCALAFKVVNDAKRGVLVYVRVYSGSLDR---------NSAIFNTNLKITERAP
RRF2M_EMENI AIKQLHGCGLAFKVVNDAKRGVLVYVRVYSGSLDR---------GSLLYNTNLNVSERAP
RRF2M_TALMQ LAANLESCALAFKVVSDAKRGVLVYVRVYSGTLNK---------GCQLYNTNLHVTERAP
RRF2M_TALSN LTANLESCALAFKVVSDAKRGVLVYVRVYSGSLNR---------NCHLYNTNLHVTERAP
G2Y660_BOTF4 LISQVEACALAFKVVNDARRGVLVYIRVYSGTVKR---------NTTLWNTNLHVSERAQ
RRF2M_YARLI DSMKNLCCALCFKVVQDPQKGTLVYVRVYKGELKQ---------NSVLYNTTSGTKDRVS
RRF2M_EREGS ----NLCLALAFKVTTDPIRGAMVFIRVYSGVLNS---------GHTVYNSSTGVKFKLG
RRF2M_KLULA ----NLCVALAFKVITDAIRGTMIFIRVYSGVLRS---------NHTVYNTTTGTKFKIG
RRF2M_VANPO ----EICVAFAFKVITDEIRGQLVFVRVYSGTLKN---------GHSVYNSTNGKTFKIN
RRF2M_YEAST ----NLCIALAFKVITDPIRGKQIFIRIYSGTLNS---------GNTVYNSTTGEKFKLG
RRF2M_YEAS1 ----NLCIALAFKVITDPIRGKQIFIRIYSGTLNS---------GNTVYNSTTGEKFKLG
RRF2M_YEAS7 ----NLCIALAFKVITDPIRGKQIFIRIYSGTLNS---------GNTVYNSTTGEKFKLG
RRF2M_CANGA ----NLCVALAFKVTHDQIRGLMVFVRIYSGVLNS---------GNTVMNTTTGEKFRIG
RRF2M_CANAL ----NLTLALAFKVMTHSTRGPMTFVRVYSGKLNA---------ASNLINTRTGKKLLIR
RRF2M_CANDC ----NLTLALAFKVMTHSTRGPMTFVRVYSGKLNA---------ASNLINTRTGKKLLIR
RRF2M_LODEL ----KLTVGLVFKVMNHATRGPMAFVRIYSGKLVA---------NSMVVNSRTGAKHSVR
RRF2M_DEBHA ----NLTTALAFKVITHPTRGVMTFFRVYSGKLTS---------NTTIMNTRTGKKLNLR
RRF2M_PICST ----NLTLALAFKVMTHATRGVMTFFRVYSGKLVS---------NSIITNTTTGKKLHVK
RRF2M_PICGU ----QLTVALAFKVMTHATRGVMTFFRVYSGSLTS---------NTTVVNTRTGKKLHLN
F4P6Y6_BATDJ -----NMTALAFKVVHDSSRGPLVYVRVYSGTLESRSILHIAGSSTGIGRDCKPIKERAT
RRF2M_SCHPO ----RPLLAKIFKVIHHASRGILTYVRVNEGTLSR---------GMMMFNPRTKKSERAI
RRF2M_HUMAN QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKP---------QLAIHNINGNCTERIS
RRF2M_PONAB QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKP---------QLAIHNINGNCTERIS
RRF2M_BOVIN QWYKGDLCALAFKVLHDKQRGPLVFMRIYSGMLKP---------QTAIHNINGNCTERVS
RRF2M_MOUSE QWYEGDLCALAFKVLHDKQRGPLVFLRIYSGTLTP---------QLAVHNINRNCTERMS
RRF2M_RAT QWYKGDLCALAFKVLHDKQRGPLVFLRIYSGTLTP---------QSAVHNVNRNCTERMS
RRF2M_DANRE RWYKNDLCALAFKVVHDKQRGPLVFVRIYSGSMKA---------QSSVHNINRNETEKMS
RRF2M_ANOGA STFRNDFVGKVFKVTHDKQRGPITMIRAFRGTVKK---------GSKFITA-TGGSETIQ
RRF2M_CULQU -CFGSDFVGKISKVTHDKQRGPLSLVRVFRGTLKK---------GAKIITA-KGTSETIQ
RRF2M_DROME -CFGTEVAGKVFKIVHDKQRGPLTLVRILRGEIKR---------GMRLISA-RGQAEVVS
RRF2M_DROYA -CFGTEVAGKVFKIVHDKQRGPLTLIRILRGEIKR---------GMRLISA-RGQAEVVS
RRF2M_DROER -CFGTEVAGKVFKIVHDKQRGPLTLVRILRGEIKR---------GMRLISA-RGQAEVVS
RRF2M_DROAN -CFGSEVAGKVFKIVHDKQRGALTLVRILRGEIKK---------GMRLISA-RGQAEVVS
RRF2M_DROPE -CFGNEVAGKVFKIVHDKQRGPLTLVRILRGEIKR---------GMRLICS-RGQAEVVS
RRF2M_DROPS -CFGNEVAGKVFKIVHDKQRGPLTLVRILRGEIKR---------GMRLICS-RGQAEVVS
RRF2M_DROWI -CFGNELAGKVFKIVHDKQRGPLTLVRVMRGELKR---------GMRLTCS-SGQAEVIS
RRF2M_DROGR -CFGNDFAGKVFKIVHDKQRGPLTLVRLLRGELKR---------GMRLLCSARGQAEVVS
. *: . :* .* * : .
RRF2M_ASPFN RLLKMYANDAVEVDSIPEGHIGVVAGL---KHTRTGDTLVTYSGNKA--TPPEP------
RRF2M_ASPNC RLLKMYANDAVEVDSIPEGHIGVVAGL---KHARTGDTLVSYAGNKL--TPPEP------
RRF2M_EMENI RLLKMYANDAVEVDSISEGQIGVVVGL---KHARTGDTLVACTTNKA--TPPEP------
RRF2M_TALMQ RLFKMYANDAVEVDSIPAGHIGVVSGL---KYARTGDTLISCTGSKM--TPPEP------
RRF2M_TALSN RLFKMYANDAVEVDSIPAGHIGVVVGL---KYARTGDTLISCTGSKS--VPPEP------
G2Y660_BOTF4 RLLQMYASDAVEIQSIPSGQIGVIAGL---KHARTGDTLLSYTGAHPKNGPPPP------
RRF2M_YARLI RLLKVHADTTSEVTSITEGNIGVILGS---QGLATGDTIVCHSIKKDGVMKLPPD-----
RRF2M_EREGS KLIKMHANVAEDIKSLHPGDIGVLAGANVADHVRTGDTIVAHCTSKDGIRSF-KK-----
RRF2M_KLULA KLVRMHANVPEEVNELYPGDIGVLTGSNVSEHIRTGDTIVTHVTKKDGLRSFDKN-----
RRF2M_VANPO KPVIMHANKTEDVQSLSAGEIGVLTGSTVFGRIETGDTLISHSMVKDGLKSIERK-----
RRF2M_YEAST KLLIPHAGTSQPVNILTAGQIGLLTGSTVENNISTGDTLITHSSKKDGLKSLDKK-----
RRF2M_YEAS1 KLLIPHAGTSQPVNILTAGQIGLLTGSTVENNISTGDTLITHSSKKDGLKSLDKK-----
RRF2M_YEAS7 KLLIPHAGTSQPVNILTAGQIGLLTGSTVENNISTGDTLITHSSKKDGLKSLNKK-----
RRF2M_CANGA KLVIMQADQAQEVKSLSPGQIGVLTGATITNKVATGDTIISHSIKKDGIRSFGEK-----
RRF2M_CANAL KLLVMHGDSPEEVKSISAGNIGVIPGY--ETDFQTGDTLVSSAVAKRNFTAK--------
RRF2M_CANDC KLLVMHGDSPEEVKSISAGNIGVIPGY--ETDFQTGDTLVSSAVAKRNFTAK--------
RRF2M_LODEL KLLIMHGDQPEEVKFIGAGNIGVISGF--EDEFHTGDTVISHATSKKAVGTM--------
RRF2M_DEBHA KLLLMHGDEPEVVPSISAGNIGVISGT--DDDIVTGDTIVSHGPVNKPFNDL--------
RRF2M_PICST KLFMMHGDEPEEVKHISSGNIGVITGH--EDDIQTGDTLVSHSHLKKGFSEM--------
RRF2M_PICGU KVLLMHGDTPEPVSQISSGNIGVITGT--ENDVITGDTLVSHGPVKRNFTDL--------
F4P6Y6_BATDJ KLLELYADDYDEIPLISAGNIGAIVGL---KHVKTGDTLLASTDKRA-------------
RRF2M_SCHPO RLYNVFADQTQEVDCISAGNIGVISGI---KQFHTGDIIINKENSKNFHEYLSG------
RRF2M_HUMAN RLLLPFADQHVEIPSLTAGNIALTVGL---KHTATGDTIVSSKSSALAAARRAEREGEKK
RRF2M_PONAB RLLLPFADQHVEIPSLTAGNIALTVGL---KHTATGDTIVSSKSSALAAARRAEREGEKK
RRF2M_BOVIN RLLLPFADQHIEIPLLTAGNIALTVGL---KHTATGDTIVSSRSSALAASRRAKREGEKK
RRF2M_MOUSE RLLLPFADQHVEIPSLTAGNIALTVGL---KQTATGDTIVSSKSSALAAARRAGR-GERE
RRF2M_RAT RLLLPFADQHVEIPSLTAGNIALTVGL---KQTATGDTIVSSKSSALAAARRAGK-GERK
RRF2M_DANRE RLLLPFADQQIEIPSLSAGNIALTVGL---KQTVTGDTIVSSKASAAAAIRRAQAEAESR
RRF2M_ANOGA RIYEPLADEYREIESFGAGNIGLCAGP---KSTVTGDLL---------------------
RRF2M_CULQU RIYAPWADEYREISSISAGNVGLCAGP---KSTVTGDLVVANASVLRNALKKLSPTNDGV
RRF2M_DROME KLYEPLADEYREVSAVQSGDVVICAGL---KSTVTGDLLTSSQSALKNAQKRYKQSLGNT
RRF2M_DROYA KLYEPLADEYREVSAVQSGDVVICAGL---KSTVTD------------------------
RRF2M_DROER KLYEPLADEYREVSAVQSGDVVICAGL---KSTVTGDLLTSS------------------
RRF2M_DROAN KLYEPLADEYREVNAVQSGDVVICAGL---KSTVTGDLLTSSQSTLKNAQKRLKQSLGTT
RRF2M_DROPE KLYEPLADEYREVGAVQSGDVVICAGL---KSTVTGDLLTSSQTALRNAQKRLKQSQGTV
RRF2M_DROPS KLYEPLADEYREVGAVQSGDVVICAGL---KSTVTGDLLTSSQTALRNAQKRLKQSQGTV
RRF2M_DROWI KLYEPLADEYREVSVVSSGDVALCAGL---KSTVTGDLLTSSQSSLKNAEKRFKQQRHSD
RRF2M_DROGR KIYEPLADEYREVGSMQAGDVAICAGL---KSTVTGDLLTSSHTSLKNAQKRLLQSRGAA
: .. : . *.: * *.
RRF2M_ASPFN -------------LNTLQLRPITVPPPVFFASVEPHSLSEEKRLQESLAMLLREDPSLHV
RRF2M_ASPNC -------------LDTLQLRPIQVPPPVFFASIEPHSLSEEKKIHECLALLLREDPSLHV
RRF2M_EMENI -------------LDTLQLRPIDVPPPVFFASVEPHSLAEEKRMHESLALLLREDPSLHV
RRF2M_TALMQ -------------LNTLQLRPIDVPPPVFFASIEPHSLSEEKNMQEALALLLREDPSLHV
RRF2M_TALSN -------------LNTLQLRPIDVPPPVFFASIEPHSLSEEKNMQEALALLLREDPSLHV
G2Y660_BOTF4 -------------LNTLQLRPINVPPPVFFAAIEPHSLSEEKNVADILQLLLREDPSLHV
RRF2M_YARLI -------------NRLIQLKPIAVPPPVFFVRIDPASIGDTRPMNEALELLLREDPSLNV
RRF2M_EREGS ------------AELALRIHPIDIPPPVFSAAVEPRTLGNKKAMDESLTQLTREDPSLVI
RRF2M_KLULA ------------VELTLKINPIEIPPPVFNAAIEPKTLGNKKPMEQALSQLTREDPSLVV
RRF2M_VANPO ------------GNLNLKINPIIIPPPVFSVYIEPKTLGNRKAMEAALKILVTEDPSLHV
RRF2M_YEAST ------------KELTLKINSIFIPPPVFGVSIEPRTLSNKKSMEEALNTLITEDPSLSI
RRF2M_YEAS1 ------------KELTLKINSIFIPPPVFGVSIEPRTLSNKKSMEEALNTLITEDPSLSI
RRF2M_YEAS7 ------------KELTLKINSIFIPPPVFGVSIEPRTLSNKKSMEEALNTLITEDPSLSI
RRF2M_CANGA ------------ES-QLKVNAIQIPPPVFSVIVEPKSLGNKKLIEDALKEITMEDPSLHV
RRF2M_CANAL -------------DSAYRLLPIDIPPPLFNAAIEPHTAGDEAYMKQCVETLIREDPSLKV
RRF2M_CANDC -------------DSAYRLLPIDIPPPLFNAAIEPHTAGDEAYMKQCVETLIREDPSLKV
RRF2M_LODEL -------------ESTIKLMPIDIPPPLFNSSIEPFTAGDEAHMKKCIDILIREDPSLKV
RRF2M_DEBHA -------------ESSLKMLPIEIPPPLFNSSIEPLTAGDTRHLNSCIQILLREDPSLKV
RRF2M_PICST -------------ESNLKLLPIEIPPPLFNSAIEPQTAGDEAYMKECVRILTREDPSLKV
RRF2M_PICGU -------------ETSIKLLPIEIPPPLFNSSIEPLTAGDARYMNECINTLIREDPSLNV
F4P6Y6_BATDJ ----------------IQLHSIPIPPPVFVRSCEAESISSEKAMAAALESLCREDPSLTV
RRF2M_SCHPO -----------------NQSVISIPEPVCIASIEPYSLKDEPALLEALANMNREDPSFRY
RRF2M_HUMAN H-------RQNNEAERLLLAGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKV
RRF2M_PONAB H-------RQNSEAERLVLAGVEIPEPVFFCTIEPPSVSKQPDLEHALKCLQREDPSLKV
RRF2M_BOVIN Q-------KENNEAERLLLAGVEIPEPVFFCTIEPPSMAKQPDLDHALKCLQREDPSLKV
RRF2M_MOUSE H-------GKKREAESLLLAGVEVPEPVFFCTIEPPSVAKQPDLDHALERLQREDPSLKV
RRF2M_RAT P-------GRISEAESVLLAGVEIPEPVFFCTIEPPSAAKQPDLDHALEHLQREDPSLKV
RRF2M_DANRE -----------SNSHSAALAGVEVPEPVFFCSIEPPTMAKQADLEHALNCLQREDPSLKV
RRF2M_ANOGA ------------LLASKLGLQTTIPDAVYFCSIEPPSSGQQSALDNALREIQREDPSLRV
RRF2M_CULQU -----EEDDINELLASKLSFHTVVPDAVYFCSIEPPSSSYQAALDAALREIQREDPSLRV
RRF2M_DROME AAKV-EEDDELDESDELFAIDPQIPDAVYFCSIEPPSVSSQTAMEQALKQLQREDPSLRV
RRF2M_DROYA -----EEDDELDESDELFAIDPQIPDAVYFCSIEPPSVSSQTAMEQALKQLQREDPSLRV
RRF2M_DROER -----EEDDEFDESHELFAIDPQIPDAVYFCSIEPPSVSSQTAMEQALKQLQREDPSLRV
RRF2M_DROAN ESVIPELDDESEESEDMFGLDPQIPDAVYFCSIEPPSISSQTAMEQALRQLQREDPSLRV
RRF2M_DROPE S----ADEDEELDTDELFGIDRQIPDAVYFCSIEPPSVSSQTAMEQALRQLQREDPSLRV
RRF2M_DROPS S----PDEDEELDTDELFGIDRQIPDAVYFCSIEPPSVSSQTAMEQALRQLQREDPSLRV
RRF2M_DROWI GMSEEEDDDEDHHLDGLFDLAPQIPDAVYFCSIEPPSISSQTAMEQALRQLQREDPSLRV
RRF2M_DROGR MPQD-EDEVLDDASHELFSIEPKIPDAVYFCSIEPPSISSQTAMEQALKQLQREDPSLRV
:* .: :. : : : : ****:
RRF2M_ASPFN TVDEDSGQTLLSGMGELHLEIARDRLLNDLKAKASMGRIEIGYRECPLGASGPITK-IFD
RRF2M_ASPNC TVDEDSGQTLLSGMGELHLEIARDRLINDLKAKATMGRIEIGYRECPLGESPVVTK-MFD
RRF2M_EMENI SIDEDSGQTLLSGMGELHLEIARDRLINDLKAKATMGPIEIGYRECPLGASGPVTK-IFD
RRF2M_TALMQ TVDEDSGQTLLSGMGELHLEIARDRLVNDFKAKATMGRIEIGYRECVLGQSNPVTK-IFD
RRF2M_TALSN TIDEDSGQTLLSGMGELHLEIARDRLVNDFKAKASMGRIEIGYRECVLDQSNPVTK-IFD
G2Y660_BOTF4 NIDEESGQMQLSGMGELHLEIAKDRLVNDFKAKATMGNIEIGYRECVLSPTLPHKY-IFD
RRF2M_YARLI SFDDETNQTTLSGMGELHLEIAQNRLIEDFKANIVIGPIIISYKETLNEPTKSITK-TVE
RRF2M_EREGS VRDEETGQTVMNGMGELHLEIAADRLLNEFKAPVRVGKVAVSYKETINTAT--------E
RRF2M_KLULA THDEETGQTLLSGMGELHLDIARDRLLNELNAQVDVERVIVSYKETLNHST--------Q
RRF2M_VANPO SQDEETSQTLLSGMGELHLEIARDKLLNDLKAEVGIGKLMISYKETINSTT--------N
RRF2M_YEAST SQNDETGQTVLNGMGELHLEIAKDRLVNDLKADVEFGQLMVSYKETINSET--------N
RRF2M_YEAS1 SQNDETGQTVLNGMGELHLEIAKDRLVNDLKADVEFGQLMVSYKETINSET--------N
RRF2M_YEAS7 SQNDETGQTVLNGMGELHLEIAKDRLVNDLKADVEFGQLMVSYKETINSET--------N
RRF2M_CANGA IIDEETGQTVLNGMGQLHLEIAKFRLVNEMKVPVDFGKIAVSYKETLELPT--------E
RRF2M_CANAL HLDKEMGQVVLSGMGELHLDIVRERLVNDMKAKVNLKDVVVSYKESFVGKR--------E
RRF2M_CANDC HLDEEMGQVVLSGMGELHLDIVRERLVNDMKAKVNLKDVVVSYKESYVGKK--------E
RRF2M_LODEL HTEEDMGQTILSGMGELHLEIVRDRLINDMKVKANLRDIAVAYKESYIGKT--------P
RRF2M_DEBHA SVDEDLGQIILSGMGELHLEIIKERLVTDMKANARLRDVAVSYKETLGKPNY-----KSV
RRF2M_PICST SVDEEMGQTIISGMGELHLDIVKERLVRDMKAKVTLRDVAVSYKETLLNP-------GSS
RRF2M_PICGU NVDEELGQTILSGMGELHLEIVRDRLINDMKAKIRLRNVAVSFKETVSKPS------LEV
F4P6Y6_BATDJ TVNDETGQTLLSGMGELHLEIAGERLQEVYNVKCNLGKVEISYRETLQAGQTYSHEMVYD
RRF2M_SCHPO TQDLENGQLLIQGMGIMHLQVSYERLVSEFGARASLGKVQVGYRETLIDVSF-----NSV
RRF2M_HUMAN RLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSV--RATDTLD
RRF2M_PONAB RLDPDSGQTVLCGMGELHIEIIHDRIKREYGLEAYLGPLQVAYRETILNSV--RATDTLD
RRF2M_BOVIN KLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYREAILNSI--RATDTLD
RRF2M_MOUSE KLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSV--RATDTLD
RRF2M_RAT KLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSV--RATDTLD
RRF2M_DANRE RIDPDSGQTVLCGMGELHIEIIHDRIKREYKIETHLGPLQVAYRETILQSA--TAKDLLD
RRF2M_ANOGA RYDEVTGQTVLGGMGQLHLEIVKSRILTEYRIDADLGPLQIAYKETLDEPC--RGEWRAE
RRF2M_CULQU SYDETTMQTVLGGMGKLHLEIIKSRILSEYKIDVDLGPLQIAYKETLEEPA--RGSWTAE
RRF2M_DROME SYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIEAPA--LTTLSVE
RRF2M_DROYA SYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIESPA--LTTLSVE
RRF2M_DROER SYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKEAIESPA--LTTLSVE
RRF2M_DROAN SYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIESPA--LTTLSVE
RRF2M_DROPE SYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIESPS--LTTLSVE
RRF2M_DROPS SYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIESPS--LTTLSVE
RRF2M_DROWI SYDSITGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIEAPS--LTTLSVE
RRF2M_DROGR SYDSVTGQTVLGGMGELHMDIIKSRMLSEYKIDVDLGPLQIAYKETLGSSA--ITTLSVD
: * : *** :*::: :: . : :.::*
RRF2M_ASPFN KEIAGRKGKAGCTATVEPFDPEE----TTTEPDPSTLSIQTTDGNQIIIQAPGLEVEVNK
RRF2M_ASPNC KEIAGRKGKAGCTAVVEPFDPDN----APPVPE-DALSVETKEGNQIIIIAPELQVETNR
RRF2M_EMENI REIAGRKGKAGCTAEIEPFDPE-----TSPAPDPAALSVEIANGNQIVILAPELQIETNK
RRF2M_TALMQ REVAGRKGKAGCTAVVEPYDPES---GEPSSGGEDIIFAEIVEGNRIIISAPGINISTDK
RRF2M_TALSN REVAGRKGKAGCTAVVEPYGQELESDGNDTSGSDDIIFTETVDGNKIIISAPGVNITTDK
G2Y660_BOTF4 REVAGKKGKAGCEASISP----------DTQPLEDSDHTMNIDGNTITIRIPK---PSNN
RRF2M_YARLI PEPG---AVSTVRLRLEPITEMD----EACENENVIDHEQNTVSFPYELSDADLESVGEG
RRF2M_EREGS TKHSETDDGYSFELEVRQYNEE--------DKVLFSNGWYPLGSDNNYLVIDPNPRF---
RRF2M_KLULA EKTLETDDGYKITAVIEPLDEEMK------AKAKKDEEWFSLANDNNFMIMEKHTKY---
RRF2M_VANPO PVIYQDDIGYKFTIQIEPLEGEEVRV----DKDTATEAWYPLGVDNNYLIFEKSNKP---
RRF2M_YEAST IETYESDDGYRFSLSLLPNSDA-----------LPNCLAYPLGVNENFLIMEKNG-----
RRF2M_YEAS1 IETYESDDGYRFSLSLLPNSDA-----------LPNCLAYPLGVNENFLIMEKNG-----
RRF2M_YEAS7 IETYESDDGYRFSLSLLPNSDA-----------LPNCLAYPLGVNENFLIMEKNG-----
RRF2M_CANGA VVTFKDERGFHFSLSVESFEKDTINI----EE-RSGASCFSVDNDENYLIIEGFQDR---
RRF2M_CANAL KEAVITNEEIEVAVTLSHIEDARD--------YVGQEGALVIEEDNNVILLSETASSEHV
RRF2M_CANDC KEAVITDEEIEVVVTLSHTEDARD--------YIGQEGALVIEGDNNVILLSQTALSEHV
RRF2M_LODEL TNGLFETESIQVKLSIEHVDDCKS--------FEDVDGAIIFEDQNNVIIVPESLASETV
RRF2M_DEBHA TQSTGDNGCVSIEISMDSFEGLAEE-----SSFADEDGAIVLEHENNIVILEPSATPEYM
RRF2M_PICST YKQTSESGSVSIEIEMDSFEGAAEE-----SSFFEENGAMIIAEDNNIIIIEPSAISQNM
RRF2M_PICGU VKASKNDGLVKVEVSLEAIDGPAEE-----STHADENGSVLLETDNNVVKLPPEAAASHI
F4P6Y6_BATDJ SQVFGKHFKCTVELEMESIDNT--------------DAGESISLATDGIIVDARLKEHQI
RRF2M_SCHPO TLSTENKENLIINVYLIPISDEGD--------ETLKKYFSEGEIQKVRSKGQEDGVLFYG
RRF2M_HUMAN RTLGDKRHLVTVEVEARPIET----------------------------------SSVMP
RRF2M_PONAB RTLGDKRHLVTVEVEARPTET----------------------------------TSVMP
RRF2M_BOVIN RTLGDKRHLVTVELEAKPVET----------------------------------SSLLP
RRF2M_MOUSE RVLGDKRHLVSAELEVRPAEE----------------------------------PCAVA
RRF2M_RAT RVLGDKRHFARAELEVRPAEE----------------------------------PCGVA
RRF2M_DANRE RILGEKRHVVSVELTVHPLKE----------------------------------NSS-A
RRF2M_ANOGA KEIAGSKQSVYMDMTIHPSTASESN------------------------------EERIV
RRF2M_CULQU KEIAGSKQLVRMEVTVHAKRK----------------------------------DERFL
RRF2M_DROME KEIAGSKQSVSITLEVVKNQA-----------------------------------ELFS
RRF2M_DROYA KEIAGSKQSVSITLEVVKNQA-----------------------------------EMFS
RRF2M_DROER KEIAGSKQSVSITLEVVKNQA-----------------------------------ELFS
RRF2M_DROAN KEIAGAKQNVSITLELVKDKS-----------------------------------EIFS
RRF2M_DROPE KEIAGSKQNVSLTLEVVKDHD-----------------------------------ELFS
RRF2M_DROPS KEIAGSKQNVSLTLEVVKDQG-----------------------------------ELFS
RRF2M_DROWI KEIAGTKQNVSITLELVKNQS-----------------------------------EIFS
RRF2M_DROGR KDIAGSKQSVSITLQLVSDQR-----------------------------------ELFS
RRF2M_ASPFN KGIEESPLLPPGLDVHALRTALQNGCLAALAR-GPQFTFPMHGTRVTLTFNPAEHLFGNE
RRF2M_ASPNC KGIEESPVLPPGLDMQSFRASLHNGCLAALAR-GPQFTFPMHHTRVTLTINPTEHLFGTD
RRF2M_EMENI KGLEESPILPPGLDVDAVRSALSNGCLAALAR-GPQFTFPMHSTRVTLTLSPTAHIFGNE
RRF2M_TALMQ RGKEESSSLPSQFDVNSFRTSLYNGALSALAR-GPQFAFPMHNTKVTLTCNVVEHLFGSD
RRF2M_TALSN KGKEESTSLPPQLDLNSFRTSLYNGALSALAR-GPQFAFPMHNTKVTLTCNAAEHLFGSE
G2Y660_BOTF4 DGVDGTMTLPSDMTLSEVHTALINGAVAGLAR-GPRRAFPLHSAHVLLKFDTVEDVFGSD
RRF2M_YARLI NQRISFERDTKELTPEIMEECFRVGSIPPLVSCGPVCRLPLRSVRVVIEAWHIAQHINN-
RRF2M_EREGS ---NED-NWPFPLKYEAFVNSIISCCIVALQRGGKTAGFPLHSCVIHVKR-WRLPLDCAA
RRF2M_KLULA ---DPDKNWPFQVPYVAVVNALLPSSLVALQRGGKIGGFPLSSCVIRIKNDWDLPIDAPS
RRF2M_VANPO ---GLGAVWKHQIPYDVVINTIKSSCLASFQRGGKIGGYALHSCAVRIKGDFEVPYDATS
RRF2M_YEAST ---NWDKEWKYQVSFESILNSIIASCIVGLQRGGKIANFPLYACSIKINSDWSVPPDIET
RRF2M_YEAS1 ---NWDKEWKYQVSFESILNSIIASCIVGLQRGGKIANFPLYACSIKINSDWSVPPDIET
RRF2M_YEAS7 ---NWDKEWKYQVSFESILNSIIASCIVGLQRGGKIANFPLYACSIKINSDWSVPPDIET
RRF2M_CANGA ---LQKSNWAYQIPIRNFVTTILSSAMASLQSAGKVGHLPLYSCAVRLKKDWDFPLDLQS
RRF2M_CANAL RATIDERRWKCENNLEELKEAILNGCLTALQMGGPILGFPLHSTLVTVNR-WNVPVEVAQ
RRF2M_CANDC QATIDERRWKCENNLEELKEAILNGCLTALQMGGPILGFPLHSTLVTVKR-WNAPVEQAQ
RRF2M_LODEL QSATEGRRWKCPSSYEELHEAVVNGCSMALQTGGPHLGLSLHSTLVKVEF-WNAPVEVNE
RRF2M_DEBHA QTAIDERRWKSDHSLEDLQESLVHGCITALQLGGPVFGFALHSTVIRIKN-WHFPVDSKD
RRF2M_PICST LKALEERRWKSTYSLEDLQEIVIQGCLTALQMGGPIFGLSLHSTVIRVKS-WDFPVADSS
RRF2M_PICGU NESLSERRWKSEHSLEELNDIILQGITTGLQLGGPILGLPLHSVVVRVIH-WDFPVEGKE
F4P6Y6_BATDJ TLAEDGRQLTAFAPLSELSEAAEMGIRGALSR-GPILGLPVSQVSVRVKQVSLFNPEIST
RRF2M_SCHPO WKPENSCTLPDHLSFQRIQENIYFGIVAGLSH-GPLHGFPLTNLQSFCTISSFLSNDFPL
RRF2M_HUMAN VIEFEYAESINEGLLKVSQEAIENGIHSACLQ-GPLLGSPIQDVAITLHSLTIHPGTSTT
RRF2M_PONAB VIE--YAESIHEGLLKVSQEAIENGIYSACLQ-GPLLGSPIQDVAITLHSLTIHPGTSTT
RRF2M_BOVIN VIE--YAASVAGDLSQASREAFENGVHSACLQ-GPLLGSPVQDVAVTLHSLVIHPGTSTT
RRF2M_MOUSE KIE--YADCVGEDLLQASREAIESAVHSACLQ-GPLLGSPVQDVAMTLHSLMIHPGTSTT
RRF2M_RAT TIE--YADSVGEDMLQAPREDIENAIHSACLQ-GPLLGSPIQDVAVTLHSLMIHPGTSTT
RRF2M_DANRE SCDITFEEDVKAMLPADVREAVENGVQSAYLQ-GPVLGFPVQGVQTVIQNVRLESGTSAA
RRF2M_ANOGA LDNSAEAQETLKLVRPRQMTFFRKGALAALQR-GPKLGGQLANCTIKLHALTIGKGTADP
RRF2M_CULQU LDSSPEAQENLRMIRPRQMSYVRKGSLAALER-GPKLGGQLMDVAVTLHQLTIGKGTADT
RRF2M_DROME LDKSPDNLPNLNTLRPRILQVLRKGSISALER-GPRVGGQVVETQIRLHNATIGRGTADS
RRF2M_DROYA LDKSPENLPNLNTLRPRILQVLRKGSISALER-GPRVGGQVVETQIRLHNATIGRGTADS
RRF2M_DROER LDKSPENLPNLNTLRPRILQVLRKGSISALER-GPRVGGQVVETQIRLHNATIGRGTADS
RRF2M_DROAN LDKSPENMPNLNTLRPRILQVLKKGAIGALER-GPRVGGQVVDTQIRLHNATIGRGTADS
RRF2M_DROPE LDKSPENLSNLNTLRPRTLQVIRKGSVSALER-GPRVGGQVVDTQIRLHNAIIGRGTADS
RRF2M_DROPS LDKSPENLSNLNTLRPRTLQVIRKGSVSALER-GPRVGGQVVDTQIRLHNAIIGRGTADS
RRF2M_DROWI LDKSPENLQNLNKLRPRIVQVLRKGSISALER-GPRVGGQVVDTQIRLHNAIIGRGTADA
RRF2M_DROGR LDKSPENVQHLNALRPRILGVLRKGAVSALER-GPRVGGQVVDTQIRLHNVTVGRGTADS
* :
RRF2M_ASPFN STPSALSAAARLATSSALRDLPS-------GAGTSLMEPVMNVIISVDEASLGAVVHDIS
RRF2M_ASPNC TTPAALSSAARLATSAALRDLLSS------GPGTSLMEPVMNVIISIDEASLGAVVHDIS
RRF2M_EMENI TTSASLSAATRLATSTALSNLISNPASASATPGTCLMEPLMNVIISVDEASLGAVVHDIS
RRF2M_TALMQ SSASALSAAARLATQGALRDLATG----QNS-GTGIMEPVMNVIISIDEASLGAVVHDIS
RRF2M_TALSN SSASALSAAARLATQGALRNLTTT----AASTGTGMMEPVMNVIISVDEASLGAVVHDIS
G2Y660_BOTF4 TTSAALSSASRNAVQAALKEAFQA-------NSIGLMEPVMNVVISCDESSLGAIVHDLS
RRF2M_YARLI --TASLKTATRLAIMEALSTANAT-----------LMEPIMNVYVSVNEADIGLVVKDLS
RRF2M_EREGS AAS--ILLTVRPLIISALTS--------LPTSAFSILEPIMNVEVTVQQQDLGSVVQDLT
RRF2M_KLULA ISP--LLTLSRQLFTQILLG--------EDQSNYSVLEPVMNVDVTVQQQDMGPVIQDLS
RRF2M_VANPO SNE--ILNITRKLIIKSLQA--------LHESSYSLLEPIMDVEIVVNQKFMGEVIQDLT
RRF2M_YEAST PQE--ILKITRNLIFKALND--------LKPEKYNLLEPIMNLDLTIPQSDVGTVLQDLT
RRF2M_YEAS1 PQE--ILKITRNLIFKALND--------LKPEKYNLLEPIMNLDLTIPQSDVGTVLQDLT
RRF2M_YEAS7 PQE--ILKITRNLIFKALND--------LKPEKYNLLEPIMNLDLTIPQSDVGTVLQDLT
RRF2M_CANGA PAE--LLSITRSLITEALQT--------VDVSNYTLLEPVMDAHISVPQNDIGTVMQDLC
RRF2M_CANAL EQALNLMNASRQAVQSLK----------DEKKDFSILEPIMSTKVYVDSNDLGEVSHDLT
RRF2M_CANDC EQALNLMNASRQAVQSLK----------NEEKDFSILEPIMSIKVYVDSNDLGEVSHDLT
RRF2M_LODEL ELIPPLMNAAREAVQSVK----------ASENKFGFLEPLMNVRVFVDSADMGEVSHDLS
RRF2M_DEBHA YNSSSLLDISRRAVTKNIKDLGE-----SEKDLFSLLEPIMQTKVYINSDSLGEVVHDLT
RRF2M_PICST VASTVLLDVSRSAVTSYI----A-----TNRDWFGILEPIMETRVYIDSDIMGEVSHDLT
RRF2M_PICGU VSASMLLDASRQVVREALSKLPE-----SS---FCILEPIMSTRVYVDSGSMGEVVHDLS
F4P6Y6_BATDJ PSSVRTAAYNCVRAIFQTAD-------------KRIIEPVMDLSVRVANQYVGSITKDLT
RRF2M_SCHPO SLLTQASMKATKNAVFSLYK--------RSPKSFRILEPYMDVTITTPEEYVGIVSKDLV
RRF2M_HUMAN MISACVSRCVQKALKKAD---------------KQVLEPLMNLEVTVARDYLSPVLADLA
RRF2M_PONAB MISACVSRCVQKALKKAD---------------KQVLEPLMNLEVTVARDYLSPVLADLA
RRF2M_BOVIN MISACVSRCLQKALKKAD---------------KQILEPLMNLEVTVSREYLSPVLADLA
RRF2M_MOUSE MVTACISRCMQKALKKAD---------------KQVLEPLMSLEVTVSREYLSPVLADLA
RRF2M_RAT MVTACISRCVQKALKKAD---------------KQVLEPLMSLEVTVSREYLSPVLADLA
RRF2M_DANRE MVSACVSRCMLKALKQAG---------------GQVLEPVMALEVTVGEEHLSSVLADLS
RRF2M_ANOGA FIMAASAQCIGNILANAR---------------CRLLEPDMFLEIVTPSEYLPPILADLS
RRF2M_CULQU FIMAATAQCVRHVLSSAK---------------CRLMEPIMLLEMVMPAEHLNPILADLG
RRF2M_DROME FVMATAAQCVQKLLSTSG---------------TRLLEPIMALQIVAPSERISGIMADLS
RRF2M_DROYA FVMATAAQCVQKLLSTSG---------------TRLLEPIMALQIVAPSERISGIMADLS
RRF2M_DROER FVMATASQCVQKLLSTSG---------------TRLLEPIMALQIVAPSERISGIMADLS
RRF2M_DROAN FVMATAAQCVQKVLSTSG---------------TRLLEPIMSLQIVAPSERISGIMADLS
RRF2M_DROPE FVMATAAQCVQKLLSTSG---------------TRLLEPIMALQIVAPSERISGIMADLS
RRF2M_DROPS FVMATAAQCVQKLLSTSG---------------TRLLEPIMALQIVAPSERISGIMADLS
RRF2M_DROWI FIMATAAQCVQKLLSENG---------------TRLLEPIMALQIVAPSERVSSIMADLS
RRF2M_DROGR FVMAAAAQCVQKLLITSG---------------TRLLEPIMAIQIVAPNERISGIMADLS
.:** * : : : *:
RRF2M_ASPFN SSRGGHIISLDEET----PLQTTGI----TSNPT-DDLLPPIDPNKVYAPPD--PFQSST
RRF2M_ASPNC SSRGGHIVSLDEEI----PLTSTDL----SASPQPVEDLPPIDPKKVYAPAD--PFESGS
RRF2M_EMENI SSRGGHIVSLDEDV----PIASTDLSIPNTETPDPELDLPPIDPAKVYAPPD--PFQSST
RRF2M_TALMQ SARGGHIISLDEEM----PISTSIG-----GNDSPESEQVVIDVNKIYAPPD--PFETPS
RRF2M_TALSN SARGGHIVSLDEEM----PISTSLS-----QSPESQDQPVAVDINKIYAPPD--PFETPS
G2Y660_BOTF4 SARGGHVLSLENDS----DVEDTEN------------ELAPVDVSRVYTPPD--PFASGT
RRF2M_YARLI GSRNGQIVSIMDPS----QLNEGDI----------HSEEYVAMATNTYVPAD--YTMYLS
RRF2M_EREGS GARKANILSIDDEHHWADAAVTDKD-----------VHLFHDIAEKQYLPPD--STVFQA
RRF2M_KLULA SARKANILSIEDE----NTNTVSES-----------NIRFQHIADKMWLPED--PTLEFA
RRF2M_VANPO GHHKANILSIEDEH--GLDYNNERS-----------TLNFKDIVDSQYLPPD--ITLNLA
RRF2M_YEAST GARKAQILSIEDES---SVSNSGAS-----------TCNSPENSNRIYIPSDAVTTLHAT
RRF2M_YEAS1 GARKAQILSIEDES---SVSNSGAS-----------TCNSPENSNRIYIPSDAVTTLHAT
RRF2M_YEAS7 GARKAQILSIEDES---SVSNSGAS-----------TCNSSENSNRIYIPSDAVTTIHAT
RRF2M_CANGA SARTATISSLDDEN-----VSSSDK-----------LMELESQSKHLYYPTD--STLGTA
RRF2M_CANAL QRCKAMIVEIQDQS-----TQNLET-----------AAWAKDEAAKVYVPPD--YTIKKN
RRF2M_CANDC QRCKAMIVEIQDQS-----TQNLET-----------AAWAKDEATKVYVPPD--YTIKKN
RRF2M_LODEL QRCQALIHSVEDES-----LLNLET-----------ANWAKDEAERAYLPPD--YTMSKT
RRF2M_DEBHA HRCQATITSIDDE------SENMDA-----------LNWANEESERVYVPPD--YTMKNT
RRF2M_PICST QRCQAVIKSIEDES-----TQDVDA-----------LAWAKDEAEKTFLPPD--YTMKAG
RRF2M_PICGU HRCSAHITSIEDE------SENMDS-----------NAWANEEAENLYLPQD--YTMKSG
F4P6Y6_BATDJ GTRKGQVLGVNAMD-----LDGADS-----------------------------------
RRF2M_SCHPO GKRGATIKEITEIG---KNAASKDS------------QIAIGILGERYLPAD--EPSSVK
RRF2M_HUMAN -QRRGNIQEIQTR-----------------------------------------------
RRF2M_PONAB -QRRGNIQEIQTR-----------------------------------------------
RRF2M_BOVIN -QRRGNIQEIQSR-----------------------------------------------
RRF2M_MOUSE -QRRGNIQEIQTR-----------------------------------------------
RRF2M_RAT -QRRGNIQEIQTR-----------------------------------------------
RRF2M_DANRE -QRRGTICDIQSR-----------------------------------------------
RRF2M_ANOGA -RRRARIEDVAPRG----------------------------------------------
RRF2M_CULQU -KRRCEILDVTARG----------------------------------------------
RRF2M_DROME -RRRALINDVLPKG----------------------------------------------
RRF2M_DROYA -RRRALINDVLPKG----------------------------------------------
RRF2M_DROER -RRRALINDVLPKG----------------------------------------------
RRF2M_DROAN -RRRAQINDVLPKG----------------------------------------------
RRF2M_DROPE -RRRALINDVLPKG----------------------------------------------
RRF2M_DROPS -RRRALINDVLPKG----------------------------------------------
RRF2M_DROWI -RRRAIINDVLPKG----------------------------------------------
RRF2M_DROGR -RRRALIRDVTSKG----------------------------------------------
: :
RRF2M_ASPFN -VGIDLPSSA-NRPRTITAKVPLKEMVGYLKHLRSLSAGRGTFVMSVDRFEKMSAPRQKA
RRF2M_ASPNC -VGASLPDTA-NRPRTITAKVPLKEMVGYLKHLRSLSAGHGTFVMSVDRFEKMSTPRQKA
RRF2M_EMENI VVGGSMASDARNRPRTITAKVPLKEMVGYLKHLRSLSAGRGTFVMSVDRFEKMSPPRQKA
RRF2M_TALMQ VAGGLPIQASANQTRTITAKVPLKEMVGYLKHLRSLSAGRGTFVMHVDRFERMSAQRQKA
RRF2M_TALSN VAGGLPIQAPANQPRTITAKVPLKEMVGYLKHLRSLSAGRGTFVMHVDRFERMSAQRQKA
G2Y660_BOTF4 ----STDSSGPGQQRQITARVPLKEMVGYLKHLRSMTGGRGTFVMSVDRFERLSGPREKA
RRF2M_YARLI ----KHQDQTRTQQSVVHARVPLREMVGYLKTLRSMTQGRGSFTMEVDQYEAVTPDKIQP
RRF2M_EREGS KLNK-----EGQTGKIVKAHVPLKEMVSYMNKLRMLTKGRGSFHMSYLGMERASSDRVDG
RRF2M_KLULA KLGK-----EGQAPKMVKAQAPLKEMVAYNNKIRSITQGRGSFNMYYHGMQPVTHDRLQS
RRF2M_VANPO KLDN-----GGDRCKVIKAEAPLKEMVSYSNKLRSLTEGRGMVYMNYHGMKKVTPERLDD
RRF2M_YEAST KDKKNTQETSSNVKKIIKAKVPLREITTYTNKLRSLSQGRGEFNIEYSDMEKVTNDRLQS
RRF2M_YEAS1 KDKKNTQETSSNVKKIIKAKVPLREITTYTNKLRSLSQGRGEFNIEYSDMEKVTNDRLQS
RRF2M_YEAS7 KDKKNTQETSSNVKKIIKAKVPLREITTYTNKLRSLSQGRGEFNIEYSDMEKVTNDRLQS
RRF2M_CANGA KIQD-------DKLKTIHAICPLKEMVTYSSKLRSLTKGRGELHMDYKGMSKVSQERIPD
RRF2M_CANAL VSKF----DDIANKKIIVAETPLREMIGYLSKLRALTRGRATFDMTLIGMRRAVGNRVDS
RRF2M_CANDC VSKF----DDIANKKIIVAETPLREMIGYLSKLRALTQGRATFDMTLIGMRRAVGNRVDS
RRF2M_LODEL ALA-----DNYKTRKVIHAETPLKEMIGYLSKLRSLTGGKATFDMSFLGMRRVTQSRLNQ
RRF2M_DEBHA NNLQ----VELRNKKVIVAETPLREMIGYLSRLRSITQGRGVFDMSYLGMKRVIKSRLAS
RRF2M_PICST KD-A----ISYKNKKIIIAETPLREMIGYLSRLRSITQGRGTFDMTYIGMRRAIKSRFDA
RRF2M_PICGU KN-A----VNFTNKKVVVAETPLRDMVGYLSKLRSITQGRGVFDMTYLGMRRAIRPVLLD
F4P6Y6_BATDJ --------NNSSEKHVIHARVPLAGLVGYSSQLRALTAGTGEFLMALHGYEPMSHDKEEL
RRF2M_SCHPO ANNASSLLQSSSVIKCIRAQVPLEQILDYNSVISSLTKGNAKFLMSHPMESQTPKLVNYG
RRF2M_HUMAN -----------QDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNT
RRF2M_PONAB -----------QDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTNQAMNPQDQNT
RRF2M_BOVIN -----------QDNKVVIGYVPLAEIMGYSTVLRTLTSGSATFALELSNYQAMNPQDQST
RRF2M_MOUSE -----------QDNRVVLGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMSPQDQSA
RRF2M_RAT -----------QDNKVVLGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMSPQDQRT
RRF2M_DANRE -----------QDNKILLADVPLAEMMGYSTVLRTLTSGNATFSLELSSYEPMNSQDQNI
RRF2M_ANOGA -----------SANKVVTVIAPLAELGDYSTVLRTISSGTASVSMEPNGHSPLNESDEAQ
RRF2M_CULQU -----------QQHKVLRANAPLAELEDYSSEVRCISSGTASVSMEPNGYALLSEMDEAS
RRF2M_DROME -----------ERNKMILVNAPLAELSGYSSALRTISSGTASMTMQPCGFSSMNSVDESL
RRF2M_DROYA -----------ERNKMILVNAPLAELSGYSSALRTISSGTASMTMQPCGFSSMNSVDESL
RRF2M_DROER -----------ERNKMILVNAPLAELSGYSSALRTISSGTASMTMQPCGFSSMNSVDESL
RRF2M_DROAN -----------ERNKMILVNAPLAELSGYSSALRTISSGTASMTMQPCGFSAMNSVDESQ
RRF2M_DROPE -----------ERNKMILVNAPLAELSGYSSALRTISSGTASMTMQPSGFSGMNAVDESL
RRF2M_DROPS -----------ERNKMILVNAPLAELSGYSSALRTISSGTASMTMQPSGFSGMNAVDESL
RRF2M_DROWI -----------DRNKLILINAPLAELPGYASTLRTISSGTASMTMQPCGFSNMNSSDESL
RRF2M_DROGR -----------DRNKIILVNAPLAELSGYSSALRTISSGTASMTMQPCGFSEMNTADESL
: ** : * . : :: * . . :
RRF2M_ASPFN VLAELRGDFF------
RRF2M_ASPNC VLTELRGGF-------
RRF2M_EMENI VLTELRGVY-------
RRF2M_TALMQ VLAELHR---------
RRF2M_TALSN VLAELNR---------
G2Y660_BOTF4 L---------------
RRF2M_YARLI IVDSIFA---------
RRF2M_EREGS ILEDADL---------
RRF2M_KLULA VLADYHQ---------
RRF2M_VANPO VLQG------------
RRF2M_YEAST ILHDL-----------
RRF2M_YEAS1 ILHDL-----------
RRF2M_YEAS7 ILHDL-----------
RRF2M_CANGA ILQEL-----------
RRF2M_CANAL IVEEYKF---------
RRF2M_CANDC IVEEYKF---------
RRF2M_LODEL IF--------------
RRF2M_DEBHA ISNEFNFM--------
RRF2M_PICST ISKEFNFM--------
RRF2M_PICGU S---------------
F4P6Y6_BATDJ LIRTMRGY--------
RRF2M_SCHPO SSFHPMSMQRQKRIFP
RRF2M_HUMAN LLNRRSGLT-------
RRF2M_PONAB LLNRRSGLT-------
RRF2M_BOVIN LLSQRHGLS-------
RRF2M_MOUSE LLNQRSGLAHVL----
RRF2M_RAT LLSQRSGLARVL----
RRF2M_DANRE LLNKMAGLT-------
RRF2M_ANOGA AMRRALGLE-------
RRF2M_CULQU AIRRAHGLE-------
RRF2M_DROME AERRAQGLE-------
RRF2M_DROYA AERRAQGLE-------
RRF2M_DROER AERRAQGLE-------
RRF2M_DROAN AERRAQGLE-------
RRF2M_DROPE AERRVQGLE-------
RRF2M_DROPS AERRVQGLE-------
RRF2M_DROWI AIRRAQGLE-------
RRF2M_DROGR AVRRAQGLD-------