CLUSTAL format seed alignment for MF_03066
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
RN168_XENLA -------------MTKEKTLPLPRSECICPICQEILLEPVTLPCKHTLCNPCFQMTVEKA
RN168_XENTR -------------MAKVQKLPLPWSECICPICQEILLEPVTLPCKHTLCNPCFQMTVEKA
E2R9S2_CANLF -------------MAAARRAVPSLSECQCRICVDILVEPITLPCGHTLCSPCFQATVEKA
M3XXR6_MUSPF -------------MAVPQNAIPSLSECLCRICVEILIEPVTLPCNHTLCNPCFQSTVEKA
M3WSK4_FELCA -------------MAVTQNAIPSLSECQCRICVEILIEPITLPCNHTLCNPCFQATVEKA
G1PJQ9_MYOLU -------------MAVPQDAIPSLSECQCGICMEIFMEPVTLPCNHTLCNACFQSTVEKA
L5L1H7_PTEAL -------------MAVPKDAIPSLSECQCGICVEILIEPVTLPCNHTLCNACFRSTVEKA
RN168_BOVIN -------------MAVPKESIPSLLECQCQICVEILFEPVTLPCNHTLCKPCFESTVEKA
W5QGI9_SHEEP -------------MAVRKDSIPSLLECQCQICVEILFEPVTLPCNHTLCKPCFESTVEKA
H0WI34_OTOGA -------------MAVPKDIIPSLSDCQCQICMEILIEPVTLPCNHTLCNPCFQSTVEKA
L9JKX5_TUPCH -------------MAVPKDAIPSLSDCQCQICVEILIEPVTFPCNHTLCKPCFQSTVEKA
RN168_HUMAN -------------MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKA
H2QP09_PANTR -------------MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKA
H2PCF9_PONAB -------------MALPKDAIPSLSECQCGICMEILVEPVTFPCNHTLCKPCFQSTVEKA
G1QLL3_NOMLE -------------MALPKDAVPSLSECQCGICMEILVEPVTLPCNHTLCRPCFQSTVEKA
A0A096N1J6_PAPAN -------------MALPKGAVPSRSECQCGICMDILVEPVTLPCSHTLCRPCFQATVEKA
A0A096MWZ4_PAPAN -------------MALPKGAVPSRSECQCGICMDILVEPVTLPCSHTLCRPCFQATVEKA
G7NZ37_MACFA -------------MALPKGAVPSRSECQCGICMDILVEPVTLPCSHTLCRPCFQATVEKA
A0A0D9R8C4_CHLSB -------------MALPKGAVPSRSECQCGICMDILVEPVTLPCGHTLCRPCFQATVEKA
F7GIE2_CALJA -------------MAVPKAAVPSLSECQCGICMEILFEPVTLPCNHTLCKPCFQSTVEKA
G5ALC0_HETGA -------------MAVPQGAVPALSECQCPICMEILVEPVTLPCRHTLCNPCFRATVEKA
A0A091ECS8_FUKDA -------------MAVSRDAVPALSDCQCPICMEILVEPVTLPCRHTLCNPCFRATVEKA
RN168_MOUSE -------------MAAPKTSIPSLAECQCGICMEILLEPVTLPCNHTLCNPCFQSTVEKA
RN168_RAT -------------MAAPKNSIPSLAECQCGICMEILVEPVTLPCNHTLCNPCFQSTVEKA
G3GSL5_CRIGR -------------MAASKEAIPSLAECQCGICMEILVEPVTLPCNHTLCNPCFQSTVEKA
G3W6K6_SARHA -------------MASPPDVELSLSDCLCQICTDILIEPVTLPCGHTLCNSCFQLTVEKA
G3W6K5_SARHA -------------MASPPDVELSLSDCLCQICTDILIEPVTLPCGHTLCNSCFQLTVEKA
F6XBK7_MONDO -------------MASTPNVVLPFSDCLCQICTDILIEPVTLPCSHTLCNSCFQLTVEKA
U3JKI4_FICAL -------------MSKKSKAPLSLSDCLCQICMEIFVEPVTLPCSHTLCNYCFQMTVEKA
G1MW43_MELGA -------------MSKKSEAPLSLDDCLCQICMEIFVEPVTLPCNHTICNSCFQLTVENA
G1KSE8_ANOCA -------------MSKDSE-APLLSDCQCNICMDIFVEPVTLPCQHTLCKSCFQLTVEKA
RN168_DANRE MPPVSEVDRGP--VEESS-GGLKRSDCVCPVCLEIFLEPVTLPCMHTFCKPCFLETVDKS
W5KS43_ASTMX MPPVSEVEPKPKLVQGGS-GQLTRADCLCPICLEIFLEPVTLPCEHTFCKPCFLETVDKA
I3KKU2_ORENI MSPVSEVESSDVGGRGQE-TTLSKEDCLCPVCLEIFMEPVTLPCTHTFCKVCFLESVDKA
A0A0F8BBR5_LARCR MAPVSDVEVSDRGAAGRTGGVLSLDDCRCPVCLEIFMEPVTLPCTHTFCKDCFLESVDKA
H2S3C6_TAKRU ---ISNVKMSGRGGRRES--TLTLQDCRCPVCLEILCEPVTLPCTHTFCKGCFLESVDKA
W5MUC6_LEPOC MPEVPKEEE-----------QLSHADCICSVCLEIFLEPVTLPCGHTFCKTCFQQTVYKA
:* * :* :*: **:*:** **:* ** :* ::
RN168_XENLA SLCCPFCRKRVSTWARLHSRTRTLVNTELWERIQKQYPKECQRRASGQESDD-----LAD
RN168_XENTR SLCCPFCRKRVSTWARQHSRTRTLVNKELWEVIQKQYPKQCQRRASGQESDD-----LSD
E2R9S2_CANLF SLCCPFCRRRVSSWTRYHTRRNSLVNAELWAVIQKHYARECKRRASGQEPE-------DV
M3XXR6_MUSPF SLCCPFCRRRVSSWTRYHTRRNSLVNMELWELIQKHYPKECKLRVSGQESE-------EI
M3WSK4_FELCA SLCCPFCRRRVSSWTRYHTRRNSLVNMELWEIIQKHYPKECKLRVSGQESE-------EI
G1PJQ9_MYOLU NLCCPFCRRRVSSWTRYHTRRNSLINKELWEVIQKHYPKECKLRASGQELE-------DT
L5L1H7_PTEAL NLCCPFCRRRVSSWTRYHTRRNSLVNRELWEIIQKHYPKECKLRASGLESE-------EI
RN168_BOVIN SLCCPFCRRRVSSWARYRSRTNSLVNMELWEIIQKHYPKECKLRASGQESK-------EI
W5QGI9_SHEEP SLCCPFCRRRVSSWARYRTRTNSLVNMELWETIQKHYPKECKLRASGQESK-------EI
H0WI34_OTOGA NLSCPFCRRRVSSWTRYHTRKNTLINMELWNIIQKHYPRECKLRASGQESEE-----IET
L9JKX5_TUPCH SLCCPFCRRRVSSWTRYHTRKNSLVNMELWEIIQKHYPKECKLRTSGQQSE-------EI
RN168_HUMAN SLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESEE-------V
H2QP09_PANTR SLCCPFCRRRVSSWTRYHTRRNSLVNVELWKIIQKHYPRECKLRASGQESEE-------V
H2PCF9_PONAB SLCCPFCRRRVSSWTRYHTRRNSLVNVELWKIIQKHYPRECKLRAPGQESEE-------V
G1QLL3_NOMLE SLSCPFCRRRVSSWTRYHTRRNSLVNMELWKVIQKHYARECKLRASGQESEE-------V
A0A096N1J6_PAPAN SLCCPFCRRRVSSWARYHTRRNSLVNVDLWKVIQKHYPRECKLRASGQESEE-------V
A0A096MWZ4_PAPAN SLCCPFCRRRVSSWARYHTRRNSLVNVDLWKVIQKHYPRECKLRASGQESEEE------I
G7NZ37_MACFA SLCCPFCRRRVSSWTRYHTRRNSLVNLDLWKVIQKHYPRECKLRASGQESEE-------V
A0A0D9R8C4_CHLSB SLCCPFCRRRVSSWTRYHTRRNSLVNVDLWKVIQKHYPRECKLRASGQEAEE-------V
F7GIE2_CALJA SLCCPFCRRRVSSWTRYHTRRNSLVNLELWTIIQKHYARECKLRAAGQESEE-------V
G5ALC0_HETGA SLYCPFCRRRVSSWTRYHTRRNSLINLELWELIQKHYPKECKRRASGQEPEE-------I
A0A091ECS8_FUKDA SLYCPFCRLRVSSWTRYHTRRNSLINMELWELIQKHYPKECKRRASGQEPEE-------I
RN168_MOUSE NLCCPFCRRRVSSWTRYHTRRNSLVNTDLWEIIQKHYAKECKLRISGQESKE-------I
RN168_RAT NLCCPFCRRRVSSWTRYHTRRNSLVNTDLWEIIQKHYAKECKLRISGQESKE-------I
G3GSL5_CRIGR NLCCPFCRRRVSSWTRYHTRRNSLVNRDLWEIIQKHYAKECKLRASGQESRE-------I
G3W6K6_SARHA NLCCPFCRRRVSSWARQHARENTLINMELWNKIQKNYPEKCKHRTTGQSS-------TET
G3W6K5_SARHA NLCCPFCRRRVSSWARQHARENTLINMELWNKIQKNYPEKCKHRTTGQSLDDDDDN-DDD
F6XBK7_MONDO NLCCPFCRRRVSSWARQHARENTLINMELWDKIQKSYPEKCKKKTTEQDLD------GDD
U3JKI4_FICAL SLCCPFCRRRVSSWARYNTRRNTLVNWELWEKIQKNYPEECERRINGQDLDE-------E
G1MW43_MELGA SLCCPFCRRRVSSWARYNARRNTLINWELWEKIQKKYPKECERRINGQDLEE-------L
G1KSE8_ANOCA TLCCPFCRRRVSSWARYNARRNTLVNSELWAKIQKHFPEECQRRISGQDIED--------
RN168_DANRE NMCCPLCRKRVSTWARLNSRNKTLVNMELWRRIQDAFPSQCERRVQGIDD--------DE
W5KS43_ASTMX NMCCPLCRKRVSTWARLNTRKKTLVNVELWKRIQKAFPVQCQRRLNGVEE--------EQ
I3KKU2_ORENI TLCCPMCRKRVSTWARLHSRNNTLVNETLWRRVQTCFPRQCEHRLSGQG--EVED----P
A0A0F8BBR5_LARCR TLCCPLCRKRVSTWARLNNRNNTMVNQQLWTRIQSTFPLQCQRRLSGQD--HANDDDLGA
H2S3C6_TAKRU TLCCPLCRKRVSTWARQNSRNNTLVNQQLWNQIQDQFPLHCQRRLSGQDGN--------V
W5MUC6_LEPOC SMCCPLCRKRVSTWCRLHSRNKTLVNAELWRKVQAAFPLQCQRKLSGQDA-------DDS
.: **:** ***:* * . * .:::* ** :* :. .*: :
RN168_XENLA ELASCPAPLLCQPGEIRQEYEAEVSKIEAERLAQEEAERKASEDYIQKLLAEEAAQDRLH
RN168_XENTR ELTSCPVPVLCKPGEIRQEYEAEVSKIEAERTAQEEAERKASEDYIQKLLAEEEAEENLH
E2R9S2_CANLF VDDYQPVRLLSKPGELRREYEEEISKVEAERRASEEEENKASEECIQRLLAEEEEEEKRQ
M3XXR6_MUSPF VDDCQPVRLLSKPGELRREYEEEISKVEAERQASKEEENKASEEYIQKLLAEEEEEEKLQ
M3WSK4_FELCA VDDYQPVRLLSKPGELRREYEEEISKVEAERRASEEEENKASEAYIQRLLAEEEEEEKQQ
G1PJQ9_MYOLU VDDYQPVHLLSKPGELRREYEEEISKVEAERRASEEEENKASEEYIQKLLAEEEEEEKRQ
L5L1H7_PTEAL VDDYQPIRLLSKPGELRREYEEEISKVEAERRANEEEENKASEEYIQKLLAEEEEEEKRQ
RN168_BOVIN VDDYQPVRLLSKPGELRREYEEEISKVEAERRACEEEENKASEEYIQKLLAEEEEEEKRQ
W5QGI9_SHEEP VDDYQPVRLLSKPGELRREYEEEISKVEAERRACEEEENKASEEYIQRLLAEEEEEEKRQ
H0WI34_OTOGA VDDYQPVHLLSKPGELRREYEEEVSKMEEERRASEEEESKASEEYIQRLLAEEEEEEKRQ
L9JKX5_TUPCH VDDCQPIHLLSQPGELRREYEEEISKVEAERRATKEEENKASEEYIQRLLAEEEEEEKRQ
RN168_HUMAN ADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQ
H2QP09_PANTR ADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQ
H2PCF9_PONAB ADDYQPVRLLSKPGELRREYEEEISKVEAERRASEEEENKASEEYIQRLLAEEEEEEKRQ
G1QLL3_NOMLE ADDYQPVRLLSKPGELRREYEEEISKVEAERRASEEEENKASEEYIQRLLAEEEEEEKRQ
A0A096N1J6_PAPAN ADDCQPVRLLSKPGELRREYEEEISKVEAERRASEEEENKASEEYIQRLLAEEEEEEKRQ
A0A096MWZ4_PAPAN ADDCQPVRLLSKPGELRREYEEEISKVEAERRASEEEENKASEEYIQRLLAEEEEEEKRQ
G7NZ37_MACFA ADDCQPVRLLSKPGELRREYEEEISKVEAERRASEEEENKASEEYIQRLLAEEEEEEKRQ
A0A0D9R8C4_CHLSB ADDCQPVRLLSKPGELRREYEEEISKVEAERRASEEEENRASEEYIHRLLAEEEEEEKRQ
F7GIE2_CALJA AYDYQPVRLLSKPGELRREYEEEISKVEAERRATEEEENKASEEYIQRLLAEEEEEDRRQ
G5ALC0_HETGA DEDCQPVRLLSQPGELRREYEEEISKVEAERRASEEEENKASEEYIQRLLAEEEEEERRQ
A0A091ECS8_FUKDA DEGCQPVRLLSQPGELRREYEEEISKVEAERRAIEEEENKASEEYIQKLLEEEEEEERRR
RN168_MOUSE IDECQPVRRLSEPGELRREYEEEISRVEAERQASKEEENKASEEYIQRLLAEEEEEEKRQ
RN168_RAT VDEYQPVRLLSKPGELRREYEEEISKVEAERQASKEEENKASEEYIQRLLAEEEEEEKRR
G3GSL5_CRIGR IDDYQPVRLLSEPGELRREYEEEISKVEAERQASKEEENKASEEYIQKLLAEEEEEEKRR
G3W6K6_SARHA VDVYKPLHLLSQPGELRREYEEEISRVEAERRAYEEEESKASEEYIQKLLAEEEEEQRR-
G3W6K5_SARHA VDVYKPLHLLSQPGELRREYEEEISRVEAERRAYEEEESKASEEYIQKLLAEEEEEQRR-
F6XBK7_MONDO VDMYQPHRTLSQPGELRREYEEEISKVEAERRAYEEEESKASEEYIQKLLAEEEEEQKL-
U3JKI4_FICAL ICSPKPRHQLSKPGELRQEYEAEISKVEAERRAHEQEENKASEEYIQRLLAEEEE-EHRL
G1MW43_MELGA VFVPHPQHQLSKPGELRQEYEAEVSKVEAERRAHEQEENKASEEYIQKLLAEEEE-EHRL
G1KSE8_ANOCA TFLPQPLRCLSKPGELRQEYEAEITKAEAERRAHEEEESKASEQYILRLLAEEEQ-EQKL
RN168_DANRE EAVMIPKPRVCQPGELRKEYEDQISKLVEEKRALEEAERRASEEYIQRLLAEEEE---RL
W5KS43_ASTMX EEVLIPKPKVSEPGELRQEYEDQVSKLMAEKQAMEEAERRASEEYIQRLLAEEEE---RI
I3KKU2_ORENI HSALVCFRRVSEPGELRQEYEDQITKLTKEKRELQEEERKASEEYIQRLLAEEEQ---LL
A0A0F8BBR5_LARCR TDTSLCYPRVSQPGEVRQEYEDQVTKLTEEKRVLDEEERRASEEYIQRLLAEEEE---LL
H2S3C6_TAKRU CVVAVCVPRVSEPGELRQEYEDQVSRLTEEKRVFEEEERRASEEYIQRLLAEEEQ---LQ
W5MUC6_LEPOC CRTLVPLRTISKPGELREEYEAQLSKLAEEKRALEEAERQASEEYIRRLLAEEEE---RQ
:.:***:*.*** :::: *: .: * :*** * :** **
RN168_XENLA SEAVQREMEEQLKIDEELARTLSVDLDVSNASCSSVSSVTSKKVVVSKSS---KNVKNKQ
RN168_XENTR AEASQREIEEQLKRDEELARLLSGDMDLSNASCTSVSPVTSKKVVS-KSS---KIVKSKQ
E2R9S2_CANLF AEKRRREMEEQLKSDEELARKLSVNINNSCDGNVLASPLNSRKSDTVTTK-SQKKSKNKQ
M3XXR6_MUSPF AEKRRREMEEQLKSDEELARKLSININNFSDGSALASPLNSRKSDTVTTK-SQKKSKNKQ
M3WSK4_FELCA AEKRRREMEEQLKSDEELARKLSININNFCDGSVLTSPLNSRKSDTVTTK-SQKKSKNKQ
G1PJQ9_MYOLU AEKRRREMEEQLKRDEELARKLSININNFCEKKVLASPINSRKSDPVTSK-LQKKSKNKQ
L5L1H7_PTEAL AEKRRKEMEEQLKSDEELARKLSININNFCEGSVLASPVNSRKSNPVTTK-LQKKSKSKQ
RN168_BOVIN AEKRHREMEEQLKSDEELARRLSLDINNFCEGSVLASPLNSRKSDPVTTK-SQKKSKNKQ
W5QGI9_SHEEP AEKRHREMEEQLKSDEELARRLSLDINNFCEESVLASPLNSRKSDPVTTK-SQKKSKNKQ
H0WI34_OTOGA SEKRRREMEEQLKRDEELARKLSININNFYEGSILASPLNSRKSDPVTIK-SEKKSKNKQ
L9JKX5_TUPCH AEKRKREMEEQLKSDEELARKLSIKINSSNEESILASPLSSRKSDPVTIK-AQKKSKNKP
RN168_HUMAN AEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPK-SEKKSKNKQ
H2QP09_PANTR AEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPK-SEKKSKNKQ
H2PCF9_PONAB AEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPK-SEKKSKNKQ
G1QLL3_NOMLE AEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPK-SEKKSKNKQ
A0A096N1J6_PAPAN AEKRRRAMEEQLRSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPK-SEKKSKNKQ
A0A096MWZ4_PAPAN AEKRRRAMEEQLRSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPK-SEKKSKNKQ
G7NZ37_MACFA AEKRRRAMEEQLRSDEELARKLSIDINNYCEGSISASPLNSRKSDPVTPK-SEKKSKNKQ
A0A0D9R8C4_CHLSB AEKRRRAMEEQLRSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPK-SEKKSKNKQ
F7GIE2_CALJA AEKRRREMEEQLKNDEELARKLSIDINNFCEGSILVSPLNSRKSDPVRAK-SEKKSKNKQ
G5ALC0_HETGA TEKRRSEMEEQLKNDEELARKLSININNFHEENILASPSNSRKSDPVTTK-FQAKKKNKE
A0A091ECS8_FUKDA AERRRSEMEEQLKNDEELARKLSININNFHEESILASPSNSRKSDPVATK-LQAKNKNKQ
RN168_MOUSE REKRRSEMEEQLRGDEELARSLSTSINSNYERNTLASPLSSRKSDPVTNK-SQKKNTSKQ
RN168_RAT TERRRSEMEEQLRGDEELARRLSTSINSNYERNILASPLSSRKSDPVTNK-SQKKNTNKQ
G3GSL5_CRIGR TQKRRSEMEEQLKGDEELARRLSVSINSNYEKNISASPSSSRKSDAVSNK-SQKKNTNKQ
G3W6K6_SARHA AKERQRELEEQMKRDEELAREISINLNKLSERSFFSSPSNTKQSSPVTNK-SQKK-TNNL
G3W6K5_SARHA AKERQRELEEQMKRDEELAREISINLNKLSERSFFSSPSNTKQSSPVTNK-SQKK-TNNL
F6XBK7_MONDO AEERKRKMAEQLKRDEELAREISINLNKLSEKSVFSSPSSAKQSSPVTNK-SQKKIKNQL
U3JKI4_FICAL AEERRKEMEKQLKQDEELAWQLSNSLNEDPEEHVPGSPSPAHSLSLQTSPLNLSKAKKKP
G1MW43_MELGA AEERRKEMEKQLKQDEELAWQLSNSLNDSLGEHVLSSSSQGDSLS------NLCKMKNKP
G1KSE8_ANOCA KEELKKQMEEQLLQDEMLARELSFSLNSSTEERMHNGLPPGPSPDSCKTS------KSKS
RN168_DANRE EEERRRREEQQLENDEKLARLLSLELN---SGPASESTCNIKPAEATPAKKKPS------
W5KS43_ASTMX AEERRMQENRQLEEDEQLARLLSEELKRS-SNSEAENYSTNRIYPDEPKQYKPSN-----
I3KKU2_ORENI RDERKRRDE-----DERLARLLSDQLN-------PPPLEDRGHVAVTPLKKKKA------
A0A0F8BBR5_LARCR QEDRRRREE-----DERLARQLSTQLN-------SAIVSQE---VVTPAKKK--------
H2S3C6_TAKRU EEQRRRHQD-----DERLARLISSQLN-------PADATPAKREVTTPAKREVTTPAKRE
W5MUC6_LEPOC AEERRREEEQQLEHDEMLARLLSQELNSNQVFQPQGNRTQVASQVQHPLVKKKRK-----
. : ** ** :* .:.
RN168_XENLA RVSGDIERFLTP-------------------RAVAVVGIDESMNSDSS----ECFIVFDE
RN168_XENTR RVSGDIERFLSPK----------------PRRALAAFGINESRNSDTS----GSCILLDE
E2R9S2_CANLF TNTGDIHKYLS--------PKPQFGS--ASQSEVVQESRENSMSKETD-SSVVKSPTQQD
M3XXR6_MUSPF TNTGDIHKYLS--------PKSQFGS--ASQSEILQGSPKNCMSKKTD-SSVVESPAWQD
M3WSK4_FELCA TNTGDIQKYLS--------PKSQFGS--ASQCEVVQESKENSMSKETD-GSIVNSPTRQD
G1PJQ9_MYOLU TNTGDIQKYLS--------PKSQFGS--ASQSEVVQEGKQKSMSKETD-SSNVKSPMWQD
L5L1H7_PTEAL INTGDIQKYLS--------PKSQLGL--ASQSEVVQEGKNNSMSKETD-SSDIKSLTWQD
RN168_BOVIN TNTGDIQKYLS--------PKSQLGS--ASQSEVVQEDRKSSMSKKIDDNSDVKSPTWQD
W5QGI9_SHEEP TNTGDIQKYLS--------PKSQLGS--ASQSEVAQEDRKNSMSKKIDDNSDVKSPTWQD
H0WI34_OTOGA RNAGDIQKYLS--------PKSQFGS--ASQSEVVQEIRKDSISKEID-NSGEKSPTWQD
L9JKX5_TUPCH TNTGDIQKYLS--------PKSHFGS--ASQSEVVQEVKKMSLSKEIE-GNDLKSLTWQD
RN168_HUMAN RNTGDIQKYLT--------PKSQFGS--ASHSEAVQEVRKDSVSKDID-SSDRKSPTGQD
H2QP09_PANTR RNTGDIQKYLT--------PKSQFGS--ASHSEAVQEVRKNSVSKDID-SSDRKSPTGQD
H2PCF9_PONAB RNTGDIQKYLT--------PKSQFGS--ASHSEAVQEVRKNSVSKDFD-SSDRKSPTGQD
G1QLL3_NOMLE TNTGDIQKYLT--------PKSQFGS--ASHSEAVQEVRRNSLSKDID-SSDRKSPTGQD
A0A096N1J6_PAPAN RNPGNIQKYLT--------PKSPFGS--ASHSEAVQEVRRNSVSK------ATKSPTGRD
A0A096MWZ4_PAPAN RNPGNIQKYLT--------PKSPFGS--ASHSEAVQEVRRNSVSKDED-DTATKSPTGRD
G7NZ37_MACFA RNPGNIQKYLT--------PKSPFGS--ASHSEAVQEVRKNSVSKDIF-PQVTKSPTGQD
A0A0D9R8C4_CHLSB RNTGNIQKYLA--------PKSPFGS--ASHSEAVQEVRKNSVSKDID-SSDMKSPTGQD
F7GIE2_CALJA RNIGDIQKYLT--------PKSQFGS--ASHSEVAQEVRENSVSKDID-SSDIKSSTWQD
G5ALC0_HETGA RNIGNIQKYLS--------PKSQFGS--ASQSEAGQEVRRNSFSKEVG-GSGVKSPVWQD
A0A091ECS8_FUKDA RNIGDIQRYLS--------PKSQCGS--ASQSEAGQEVRRNSISKEVA-GSSVKSPVQRD
RN168_MOUSE KTFGDIQKYLS--------PKLKPGT--ALACKAELEEDI-CKSKETD-RSDTKSPVLQD
RN168_RAT KNFGDIQRYLS--------PKSKPGT--AWACKTEHGEDM-CKSKETD-SSDTKSPVLQD
G3GSL5_CRIGR KNFGDIQKYLS--------PKLKSGS--AWPCEALCGEDKSCLSKEIG-SSDMKSPVWQD
G3W6K6_SARHA NVFGSIQKYLS--------PKSQFASIQTSQPEFASEDKWNSLPKDVS-SNNVKTPVWQE
G3W6K5_SARHA NVFGSIQKYLS--------PKSQFASIQTSQPEFASEDKWNSLPKDVS-SNNVKTPVWQE
F6XBK7_MONDO SFLGSIQKYLS--------PKSQFASVQASQLELATEDNGNHMSQDVS-NNNVKSTGSQE
U3JKI4_FICAL SNSGDIQKYLS--------PKNYGMLGSASFSSTTGRGRNNSISVETNSNEGSSS-ALQD
G1MW43_MELGA SNSGDIQKYLT--------PKHRHTSRSASFSRATEGGGTNPGFVISN-NEGSSA-EGQD
G1KSE8_ANOCA SNSADIKKYLSQKSCKIFAPKLLVRESEEENTSCSGVSNKNSFTLEKERMDEMLTESLQT
RN168_DANRE --VGDIEKFLRPVP----------------------------------------------
W5KS43_ASTMX --KNKSKMFLCPVP----------------------------------------------
I3KKU2_ORENI ASVGHIEKFLSPRV----------------------------------------------
A0A0F8BBR5_LARCR EVSGQIEKFLCPR-----------------------------------------------
H2S3C6_TAKRU VTTGQMDKFLSPR-----------------------------------------------
W5MUC6_LEPOC -SGGDIEKYLSPIS----------------------------------------------
. :*
RN168_XENLA GEDE----MPELSPQCPSTSLIQ-----ERGVELIMPYLSDCYKVESNTTSQQDRCSERS
RN168_XENTR DEDE----IPDLSPQCPSTSLIQ-----ERDVELPMPYLPNCYKLESDAASQQDSCSERN
E2R9S2_CANLF TEIEED--MPTLSPQIRIEMQE---QGEKSL-ESPMPQLRANG-REWCLEGKVQMSTTNH
M3XXR6_MUSPF TEIEED--MPTLSPQICMEIQE---KGEKSS-ESPMPQLCASG-REWCLEGKVKMRPTNH
M3WSK4_FELCA TEIEED--MPTLSPQIGMDVQE---QGAKSSVESPMPQLYASG-REWCLEAEVKMRPSNH
G1PJQ9_MYOLU TEVEED--MPTLSPQICLEIQE---QGAKSSIESTMPQLCASD-TEWCLEGEVKMRPNNH
L5L1H7_PTEAL TEIEED--MPTLSPQICLEIQE---QGTKSSVESPMPQLCANG-IEWCLEGEVKIKPSNH
RN168_BOVIN TEVEED--MPTLSPQIYLEVQE---QGAKSSVESPMPQLYTSD-GEWYLEGKVETGPSNH
W5QGI9_SHEEP TDVEED--MPTLSPQIYLAVQE---EDAKSSVESPMPQLCTSG-GEWCLEGKVETGPSNR
H0WI34_OTOGA TEVEED--MPTLSPQICLENQE---QSAKSSMESPMPWLCAYS-SEWCLEGKVETRPNNH
L9JKX5_TUPCH IESEED--MPILSPQVCLEIQE---QDAKSSIESPMPWLCADG-AERCLEGKVETRPNNH
RN168_HUMAN TEIE-D--MPTLSPQISLGVGE---QGADSSIESPMPWLCACG-AEWYHEGNVKTRPSNH
H2QP09_PANTR TEIE-D--MPTLSPQISLGIGE---QGADSSIESPMPWLCACG-AEWYHEGNVKTRPSNH
H2PCF9_PONAB TEIE-D--MPTLSPQISLGIGE---QGADSSIESPMPWLCACG-AEWYHEGNVKTRPSHR
G1QLL3_NOMLE TEIE-D--MPTLSPQIPLGIGE---QGADSSIESPMPWLCACG-AEWCHEGNVKTRPSNH
A0A096N1J6_PAPAN TEME-G--MPTLSPQIPLGTGE---QGADSSAEPPMPWLCACG-AEWYHEGNVKTRAGNH
A0A096MWZ4_PAPAN TEME-G--MPTLSPQIPLGTGE---QGADSSAEPPMPWLCACG-AEWYHEGNVKTRAGNH
G7NZ37_MACFA TEME-D--MPTLSPQIPLGTGE---QGADSSAEPPMPWLCACG-AEWYHEGNVKTRAGNH
A0A0D9R8C4_CHLSB TEME-D--MPTLSPQIPLGTGE---QGADSSAESPMPWLYSCG-AEWYHEGNVKTRAGNH
F7GIE2_CALJA TEIE-D--MPTLSPQICLGIGE---QGADSSVESPMPWLCACG-AELYHERKVKAGPNNH
G5ALC0_HETGA IEAE-D--MPTLSPQMCLEAQD---PSPRSSVDSAMPWLCAYD-TDQCLEGKVKTRSDNH
A0A091ECS8_FUKDA VEAE-E--MPTLSPQMCLEVQE---PSARSLADSVMPWLCAYD-ADQCLEGKVKTRSDSH
RN168_MOUSE TEIEKN--IPTLSPQTCLETQE---QGSESSAGIPGPQLCVGD-TKESLEGKVETVSTSP
RN168_RAT TDVEES--MPTHSPQTCPETQG---QGPEPLTEMPVPWLCARN-AEQCLEGKAEAVSTNP
G3GSL5_CRIGR TEIEKD--MPTLSPQICLETQE---QGSGSSAESPVPWLCAGD-AEQCLEGTVETLSTNG
G3W6K6_SARHA EDDDED--MPTLSPQAFLESQSR--VAKGSIIDSPMPRLSAFSVEEDCLEKETKSQISNP
G3W6K5_SARHA EDDDED--MPTLSPQAFLESQSR--VAKGSIIDSPMPRLSAFSVEEDCLEKETKSQISNP
F6XBK7_MONDO EEEEEDEVMPTLTPQTFLESQSR--VTKNSITDSPMPHLSAFSLEEECLEKETNSQVNNL
U3JKI4_FICAL EQEE----MPTLSPQLTNVNKE--------SAAKDSFLESCMNYFSASA-----SAKGED
G1MW43_MELGA EQEE----MPTLSPQLSETTTVKQKNTHEPNCLRDELLHTTCGIAEEGARTVLPTSKGED
G1KSE8_ANOCA ISATRNTVDSYIEPSLLDSNIGNSTEPSFPGLDLSCPSTCKMNGLVSVTDREDCETVCLF
RN168_DANRE --------------------------------------HRQP---SSSDSSPDSSLMANK
W5KS43_ASTMX --------------------------------------FRQ----TSAETSPTSTLSANK
I3KKU2_ORENI --------------------------------------APPSS-TCSSTCSSTSSHVSNK
A0A0F8BBR5_LARCR ----------------------------------------------PSKSSSDCSFTANK
H2S3C6_TAKRU ----------------------------------------------PSQCSPADSKLTAN
W5MUC6_LEPOC --------------------------------------HRSSTCHVHPETGQSAGLSANK
RN168_XENLA Q-----VCNGTYSSCSDSIDMEESMAIKKQSTTAGLFPERGYHSPENGMESNTMNCSTPK
RN168_XENTR D-----ICNGTYS-CSDSIDVEVSKTMEQQRATAD--------SQEYRMETNAMSYSTPK
E2R9S2_CANLF D---KELHVLNHEGPEARVPCSGETAVKPYGKTESGCT-ISGMTQ-IIGSNTVETENEES
M3XXR6_MUSPF D---KELCVLNHEGPEARVPCSGEAAAKPYGKTESGRT-VSGTTQ-ITASNTVTTENEES
M3WSK4_FELCA D---KELCVLNHEGPEARVPCSGE--------TESACT-ISGMTQ-IIESNTVETENEDS
G1PJQ9_MYOLU E---KELCAINPERPEARVPHPREAAVKPCGETKSGCA-LSYMTQ-IIGNNTVETENEES
L5L1H7_PTEAL D---KELCVINHEGPKASIPYSREAAVKPYGKTESGCT-IPDMTQ-IIGNNTVETENEES
RN168_BOVIN E---KGLCVINLEEPKARVPYSGDAATEPCGETESECT-VSYMTQ-FLRNNTVGTENEES
W5QGI9_SHEEP E---KGLCVISLEEPKARVPYSGDAATEARGETESECT-VTDTTQ-FLRNNTVGTENEES
H0WI34_OTOGA D---KELCVLNHEGPQTKIPYSKEAAGKPCGKTESGCT-VSGMTQ-IIGNNTVETKNEES
L9JKX5_TUPCH D---EELCAINHEEPKTSVAYSREAAVTPCDKTESGCT-VSGMTP-ITGNNAVETENEES
RN168_HUMAN G---KELCVLSHERPKTRVPYSKETAVMPCGRTESGCAPTSGVTQ-TNGNNTGETENEES
H2QP09_PANTR G---KELCVLSHERPKTRVPYSKETAVMPCGRTESGCAPTSGVTQ-TNGNNTGETENEES
H2PCF9_PONAB G---KELCVLSHEQPKTRVPYSKETAVMPCARTESGCAPTSGVTQ-TNGNNTGETENEES
G1QLL3_NOMLE E---KELCVLSHERPETRVPYSKETAVTPCGRTESGCAPTSGVTQ-TNGNNTGETENEES
A0A096N1J6_PAPAN D---KEFCVLSHEGPKTRVPDPKEAAVTPCGRTESGCAPTSGVTQ-TNGDNTGEAENEEL
A0A096MWZ4_PAPAN D---KEFCVLSHEGPKTRVPDPKEAAVTPCGRTESGCAPTSGVTQ-TNGDNTGEAENEEL
G7NZ37_MACFA D---KELCVLSHEGPKTRVPDPKEAAVTPCGRTESGCAPTSGVTQ-TNGDNTGEAENEEL
A0A0D9R8C4_CHLSB D---KEFCVLSHEGPKTRVPDPKEAAVTPCGRTESGCAPPSGVTQ-TNGDNTGEAENEEL
F7GIE2_CALJA D---T-TCVLTPEGPETRDCDSKETAVVPIGRTESGCA-TSGITQ-ANRNNTGETENEES
G5ALC0_HETGA D---TELCVTHHAGRKARVPSTKP------GDK-GNEGNLSGGTQ-VTVDCTMETENEES
A0A091ECS8_FUKDA D---AEMCVTNHAGPEAKAPSVKH------GDKAGNGGTLSGGTQ-GITDCTIGTKNEET
RN168_MOUSE D---D-LCIVNDDGPRATVFYSNEAAVNSSSKIENEEYSVTGVPQ-LTGGNRVPTESRVY
RN168_RAT D---D-SCIVNDGGPRAIVSNSKEAAVKPPTKIENEEYSVSGVTQ-LTGGNGVPTESRVY
G3GSL5_CRIGR D---D-LCVVNHEGSKVKVSYSIEATVKPPGKIENKECSVSGVTQ-LADSNRVP-ESRVY
G3W6K6_SARHA N---NELFCTNHE-VQTRFLSSGDAVAKSPGKPENGYT-LSNLAE-ITKNNAVDTENEDR
G3W6K5_SARHA N---NELFCTNHE-VQTRFLSSGDAVAKSPGKPENGYT-LSNLAE-ITKNNAVDTENEDR
F6XBK7_MONDO NEVINGHFCANHE-VQTGFLCSAEIGATSPRKAENGNA-VSNLAE-ITINSIDDTENEDR
U3JKI4_FICAL GGIETDNGNLTHIQRANLENSDDTCTSGQLGVGCGMSDSQTALCD-PGKEPGHAGGETPQ
G1MW43_MELGA G-IVLDSDSLTHVDSINLENCAETSTCIQLAIKS-MSDSKSVKGD-LLKTAGNADEKKPE
G1KSE8_ANOCA SKSSEAGYDVKKDNFTGNLDRPNHPGNAAPQETLFSVTSDNQQDSSIPTCNQVKMENKNE
RN168_DANRE E------NILSPPKPLSALSAEDCGKLTVHMLECNGKPSTSSFNPSTSE------HTFVF
W5KS43_ASTMX E------NILSSPTTLWPCPKNPPSSNEMPGLDYFGMPSTSKFGQDSSE------QLSAN
I3KKU2_ORENI E------NILVSEAALPAERR--PPQLDYYGPET-DLRPP---EEVAER----QPGSQAI
A0A0F8BBR5_LARCR E------NILVSPVKLQAECS--PPKLDYYGDTS-DPPPPSGEEEEEERDLPESHRSHLT
H2S3C6_TAKRU K------ESMVSLSSLHQ------LELHGLGSESPDLLPTFLTSATMDQ-------FHVS
W5MUC6_LEPOC E------NISFSGPVFNE------QGIPKLSPQAKSRFSERTCGELVEE-----PSMPEL
RN168_XENLA HLGMTGTLKRKCEDCSIDLEEKAGSCRNVKKKK----LSLTEDCPVPSVHA-GKLIELEE
RN168_XENTR ---------RKCEECYLDIEEKAGSCQSVKKKK----LSLSEDSPVLSVHA-GKFIELEE
E2R9S2_CANLF CLPISKD-ISKRKKQESLSEAARDPCVSAKRRKKFPKASSDQEETEINFT--QKLIDLER
M3XXR6_MUSPF CLPISKD-ISKRKNPESLSEAVRDPCVSAKRRKTFPEASSDQEEAEINFT--QKLIDLER
M3WSK4_FELCA CLLTSKD-TSKRKNQESSFEAVRDPCISAKRRKMFPRASSDQEETEINFT--QKLIDLER
G1PJQ9_MYOLU CLLISEEGICKRKNQESSFEAVRDPCFSAKRRKMSSESSSDQEETETSFT--QKLLDLEH
L5L1H7_PTEAL HLLISKEDISKRKNQESSFEAVRDPCFSAKRKKMVPKASSDQEEAEINFT--QKLLDLEH
RN168_BOVIN HLQISKG-TSKRRNLEPLSEAIREPCFSAKRRKMFPKASSDQEETEISLT--QKLIDLEH
W5QGI9_SHEEP HLPISKG-TSKRRNLEPLSEAIREPCFSAKRKKTFPKASSDQEETEISLT--QKLIDLEH
H0WI34_OTOGA -HLISLD-ISKRKNEESLFKAAKDPCFSGKRRKMFPRCSSDQEETEINFT--QKLINWEH
L9JKX5_TUPCH CLLISED-ISKRKNHGPSFEASKDPCFSVKRRKMSPKSSSDEEDTDISFT--QKLIDLEH
RN168_HUMAN CLLISKE-ISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEETEINFT--QKLIDLEH
H2QP09_PANTR CLLISKE-ISKRKNQESSFEAVKDPCFSAKRRKMSPESSPDQEETEINFT--QKLIDLEH
H2PCF9_PONAB CLLISKD-ISKRKNQESSFEAVKDPCFSAKRRKMSPESSPDQEETEINFT--QKLIDLEH
G1QLL3_NOMLE CLLISKD-ISERKNQESSFEAVKDPCFSAKRRKMSPESSPDQEETEINFT--QKLIDLEH
A0A096N1J6_PAPAN GLLIRKD-ISKRKNQESSFEAVEDPCFPAKRRKTSSECSPDQEETEINFT--QKLIDLEH
A0A096MWZ4_PAPAN GLLIRKD-ISKRKNQESSFEAVEDPCFPAKRRKTSSECSPDQEETEINFT--QKLIDLEH
G7NZ37_MACFA GLLISKD-ISKRKNQESSFEAVEDPCFPAKRRKTSPECSPDQEETEINFT--QKLIDLEH
A0A0D9R8C4_CHLSB GLLISKD-ISKRKNQESSFEAVEDPYFPAKRRKTSPECSPDQEETEINFT--QKLIDLEH
F7GIE2_CALJA CLLISKD-ISKRKNQESSFEAVKDACFSAKRRKMFPSSSSDQEETETNFT--QKLIDLEH
G5ALC0_HETGA GPLLSKD-VSKRKHQEPASEAARDPCCSVKRKKMFPKSSSDQEETEINFT--QKLIDLEH
A0A091ECS8_FUKDA DSLLSSD-VSRRKHQEPASEAAGDPCCSVKRRKMSPKSSPDQEETERNFT--QKLIDLEH
RN168_MOUSE HLLVEEE-ISDRENQESVFEEVMDPCFSAKRRKIFIESSSDQEETEVNFT--QKLIDLEH
RN168_RAT DLLVGKE-ISERENQESVFEEVMDPCFSAKRRKIFITSSLDQEETEVNFT--QKLIDLEH
G3GSL5_CRIGR HLVVGKE-ISEKENQESVLEAVMDPCFSAKRRKMFLKSS-DQEETEVNFT--QKLIDLEH
G3W6K6_SARHA SMQIEKE-ITKRKDEEFPSGAVSDSSSSAKRRKLCMGTSSEQEETDSNIA--QKLIDLEH
G3W6K5_SARHA SMQIEKE-ITKRKDEEFPSGAVSDSSSSAKRRKLCMGTSSEQEETDSNIA--QKLIDLEH
F6XBK7_MONDO NLLIGKE-SPKRKDQESPD-LVSDSSNSAKRRKFCMEISSEQEETENNIA--QKLIDLEH
U3JKI4_FICAL RLQNSKE-TPKRKLLEAPADAMIDLGMFDKRRRTSSESVEDQEEQMSNFNL-QTQRAFEQ
G1MW43_MELGA SLPNTKE-APKRKSPEQLAEAVVDLGVVDKRRRTFPGTLEEEAEWKSDFNL-QMQKAFEQ
G1KSE8_ANOCA SLKLFTTEIHKRKSQESPSKTVVDLVMNDKRRRTFTQIDDEDDMDNIQQQ-----IYLEQ
RN168_DANRE NTPKSSSVKRKSSEIELQSEVDLHSKRPCALLRFDSSSEDSPFLSEVAVH--------EE
W5KS43_ASTMX RVNISS--KRKTLDTDLAAEDAYFNKRPCGSVRPEPSPKED-ILQELALQ--------EE
I3KKU2_ORENI RDGGCSSVKRKSSELEATEEVTADTKR----VSPHFLGSSSFSLLEAA----------EQ
A0A0F8BBR5_LARCR GDGGPSLAKRKSSELETTEEEKVTKRA----CRSLPSSSSSYSSLEGGGSVLQGIVDWES
H2S3C6_TAKRU TDGETSSKRSHS------DDRRTPPKR----VCLQPCSTSRPDMPAV-------------
W5MUC6_LEPOC TFCGKMDCCRDLSETPIKSEDMQCRDTEWGPEQSTYVFNNGGCSTDLRSS--------FE
RN168_XENLA NLYERRRQEEQDRLLALQLQRELD--KELKQVNRGKGSPDEYELRTKRGLKLQECLKLQE
RN168_XENTR NLYERRKQEEHDRLFALQLQRELD--KELKQVNRGKGSPDEYQLRPKRG------LKLQE
E2R9S2_CANLF LLFERHKQEEQDRLLALQLQKEVD--KEQMKPNRQKGSPDEYQLRPT---SSPPDKLLNG
M3XXR6_MUSPF LLFERHKQEEEDRLLALQLQKEVD--KEQKKPNRQKGSPDEYHLRPT---SSPPDRLLNR
M3WSK4_FELCA LLFERHKQEEQDRLLALQLQKQVD--KEQMKPNRQKGSPDEYQLRPT---SSPPDKLLNG
G1PJQ9_MYOLU LLFERRKQEEQDRLLALQIQKEVD--KEQMKPNRQKGSPDEYHLRST---PSPPDKLLNG
L5L1H7_PTEAL LLFERHKQEEQDRLLALQLQKEVD--KEQMKPNRQKGSPDEYQLRAT---PSPPDKLLNG
RN168_BOVIN LLFERHKQEKQDRLLALQLQEEVD--QEQMRPDRQKGSPDGYQLRTV---SSPPDKVLNG
W5QGI9_SHEEP LLYERHKQEKQDRLLALQLQEEVD--QEQIRPDRQKGSPDGYQLRTV---SSPPDKVLNG
H0WI34_OTOGA LLFERHKQEEQDRLLALQLQKEVD--KEQMTPNRQKGSPDEYPLRST---PSPSDKLLNR
L9JKX5_TUPCH LLFERHKQEEQDRILALQLQKEVN--KEQMMPNRQKGSPDEYQLRAT---PSPVDKTLNG
RN168_HUMAN LLFERHKQEEQDRLLALQLQKEVD--KEQMVPNRQKGSPDEYHLRAT---SSPPDKVLNG
H2QP09_PANTR LLFERHKQEEQDRLLALQLQKEVD--KEQMVPNRQKGSPDEYHLRAA---SSPPDKVLNG
H2PCF9_PONAB LLFERHKQEEQDRLLALQLQKEVD--KEEMVPNRQKGSPDGYHLRAT---SSPPDKVLNG
G1QLL3_NOMLE LLFERHKQEEQDRLLALQLQKEVD--KEQMVPNRQKGSPDEYHLRAT---SSPPDKVLNG
A0A096N1J6_PAPAN LLFERHKQEEQDRLLALQLQKEVD--KEQMVPNRQKGSPDGYHLRAP---SSPPDRVPDG
A0A096MWZ4_PAPAN LLFERHKQEEQDRLLALQLQKEVD--KEQMVPNRQKGSPDGYHLRAP---SSPPDRVPDG
G7NZ37_MACFA LLFERHKQEEQDRLLALQLQKEVD--KEQMVPNRQKGSPDGYDLRAP---SSPPDRVPDG
A0A0D9R8C4_CHLSB LLFERHKQEEQDRLLALQLQKEVD--KEQMVPNRQKGSPDGYHLRAP---SSPPDRVPNG
F7GIE2_CALJA LLLERHKQEEQDRLLALQLQKEVD--KEQTKPNRQKGSPDEYHLRAT---SLPPDKVRNG
G5ALC0_HETGA LLFERHKQEEQDRLLALQLQEEEK--KEQRKPSRE-----EYELRAA---SMPPDRLLTA
A0A091ECS8_FUKDA LLFERHKQEEQDRLLALQLQEEEE--KEQRKPSHK-----EYELRAAA--STPPSKLLTA
RN168_MOUSE MLFERHKQEEQDRLLALQLQKEVD--KEQMVPNRQKGSPDQYQLRTP----SPPDRLLNR
RN168_RAT MLFERHKQEEQDRLLALQLQKEAD--KEKMVPNRQKGSPDQYQLRTS----SPPDGLLNG
G3GSL5_CRIGR MLFERHKQEEQDRLLALQLQKEVD--KEPMTLNRQKGSPNQYQLRTS----SPPDRLLSK
G3W6K6_SARHA LLFERHKQEEQDRLLALELQREVD--KEQMKLNRQKGSPDAYPLRTKV--SSHPDDSPND
G3W6K5_SARHA LLFERHKQEEQDRLLALELQREVD--KEQMKLNRQKGSPDAYPLRTKV--SSHPDDSPND
F6XBK7_MONDO LLFERHKQEEQDRLLALELQREVD--KEQGKLNRQKGSPDAYPLRTKV--SLHPDESPNG
U3JKI4_FICAL EFYERRRQEEQDRLLALQLQKELD--KEERTLNRQKGSPDEYLLRTKPPRSLKDSSARKA
G1MW43_MELGA ELHERHMQEEQDRLLALQLQRQFN--KEERLLNRQKGSPDEYLLRTKTPQSVKDS-SRKG
G1KSE8_ANOCA TIYERYKQEEEDRLLALQLQREMD--KEQKTLNRKKGSPDEYHLRPK---TSQSEREFPV
RN168_DANRE ALRSRWQQEEEDRRLALRIQKELD---RENSVDRRKGSADSYQLRQKNTSVSTTTSPDVE
W5KS43_ASTMX ILLSRWQQEEEDRRLAQQLQRELD---RESTVDRRKGSADGYLLREKTSPSSTSTSP---
I3KKU2_ORENI ELQERRRQEEDDRQLALILQKQLDQEEKRCATDRSKGSTDAYQLRPHRG-----------
A0A0F8BBR5_LARCR ELQSRRQQEEEDRRLALLLQKELDQEEKQRATDRRKGSSDAYLLRQNRR-----------
H2S3C6_TAKRU EQLSRQQQEEEDHRLALLLQKELDQEERD--VNRRKGSSDAYSLRLSSQ-----------
W5MUC6_LEPOC SMGTAERDGELSADTRQGPHTKTDVRKRKSKECRQEIDSELASKRLKAVAI---------
: : . : : . . : *
RN168_XENLA CQDSPLPLRKEIPVQDNSRNTQSEYSPDENK-KPSRKNSVRSARV----RQSRAVANTEG
RN168_XENTR CNDSPLPHNEQTPVQDKGGNTQSGYSPDENK-KPSRKKSITSSQV----RQSRAVTNTER
E2R9S2_CANLF QRKNSKT-RNFKKQTDLEHSKSRRGSKNENW-QASFKIQLKHSVN--GRKMPNSSRDNCN
M3XXR6_MUSPF QRKNSKD-RNFKRQTDTEHSKSRRGLKNENW-QPSFKIQLKHSVNVNGRKMPNSSRDNTN
M3WSK4_FELCA QRKNSKD-RNFKRQTDIEHSESRRGSKNENW-QPSFKIQLKHSVNVNGRKVPNSSRDNCN
G1PJQ9_MYOLU QRKKSKN-RNVKGQAGTEHPKPQRGPKTENC-QPSFKTKLRHSVNVNGRKMPNSARDHCN
L5L1H7_PTEAL QRKNPKD-RNLRGQTDREHSKPQRSSKNENW-HPSFNIQLKHSVNVKRRKMPKS-RDNYN
RN168_BOVIN QRKNSRD-RNSKRQTELEQPKPRTDSKNENHQQPSFKIQLKCSVN--RRKIANSTNDNCN
W5QGI9_SHEEP QRKNSRD-RNSKRQTELEQPKPQTDSKNENHRQPSFKIQLKCSVN--GRKVANSTRDNCN
H0WI34_OTOGA QRKNPKD-RSFTRQSDTERSKPRRGSKDENW-QSSLKIQLRHSIN--GRKRPNSTRNNSK
L9JKX5_TUPCH QRKNSRD-RNFKRQTDSEHSKPRRGSRDENW-KPASKTQVKRSVN--GRKTPHSARDNCN
RN168_HUMAN QRKNPKD-GNFKRQTHTKHPTPERGSRDKNR-QVSLKMQLKQSVN--RRKMPNSTRDHCK
H2QP09_PANTR QRKNPKD-GNFKRQTHTKHPTPERGSRDKNR-QVSLKMQLKQSVN--RRKMPNSTRDHCK
H2PCF9_PONAB QRRNPKD-GNFRRQTHTEHPTPERGSRDENR-QLSLKMQLKQSVN--RRKMPSSTRDHCK
G1QLL3_NOMLE QRKNPKD-GNFKRQTHTEHPTPERGSRDENR-QLSLKMQLKQSVN--RGKTPNSTRDRCK
A0A096N1J6_PAPAN QRKNPKD-RNSKRHTHTEHPKPQRGSRDENR-HLSLKMQLKHSVN--GRKMPNSSRDQCN
A0A096MWZ4_PAPAN QRKNPKD-RNSKRHTHTEHPKPQRGSRDENR-HLSLKMQLKHSVN--GRKMPNSSRDQCN
G7NZ37_MACFA HRKNPKD-RNSKRQTHTEHPKPQRGSRDENR-HLSLKMQLKHSVN--GRKMPNSSRDQCN
A0A0D9R8C4_CHLSB QRKNPKD-RNSKRQTHTEHPKPQRGSRDENR-HLSLKMQLKHSVN--GRKMPNSSRDQCN
F7GIE2_CALJA QRKNSKD-RNFKRQTDTEHPKPERGSRDENR-QLSVRMQLRHSVN--GRKTPNSTRDPCN
G5ALC0_HETGA QREASGD-HSLKIQTAAEHPRLRRGSRDENW--QPFTVQLRPSVN--GRKMPKSSRDHCS
A0A091ECS8_FUKDA QREASGD-HSLKRQTATEHPRLRRGSRDENW--QPFRVQRRPSVN--GQKMPKSSRDHCS
RN168_MOUSE QRKNSKD-RNSLQQTNADHSKSPRNTKGDYW--EPFKNTWKDSVN--GTKMPTSTQDNCN
RN168_RAT QRKNVKD-RNSPKQ-TADRSKSQRSRKGEYW--ETFESTWKGSVN--GTKMPTPRKDSCN
G3GSL5_CRIGR QRKNSKD-RNSEKPTNSETSKSQRSTKDEYW--QPFKSTWKDSVN--GRKKSSTKNVCSN
G3W6K6_SARHA WRRHSKE-KNCKKQPETELSKPRRSSKDENW-QPSPLIQKKISAN--------KGGKACN
G3W6K5_SARHA WRRHSKE-KNCKKQPETELSKPRRSSKDENW-QPSPLIQKKISAN--------KGGKACN
F6XBK7_MONDO WRKHSQE-KNCKKQPETELSKPRRSSKDENW-QPS-GIQKKISAN--------KGGKAPK
U3JKI4_FICAL TSRVAKDSKGSKTQAETNHHKARKGSCNENW-QSPAKVRVKSPSIK-EGKVLNCVVNTSD
G1MW43_MELGA SSKMAKDSKVSKKQSETNHYKGRKGSCNENW-QSPTRVRMKSPSS---GKVLNCVVNTSD
G1KSE8_ANOCA LRKPCKN-----SQTNREQQKSRRSSHNENR-KPSNKLQTKSSPK-----GGNVLNCVLN
RN168_DANRE GTKKGSNTTTAKNCTGRRGEEKTEKRLSGTT-----------------PGKRPGVKTPVS
W5KS43_ASTMX GEERGNTSDSVKTKAGSVKKSSRAHQEGKTT-------------------KKSHVCTQSS
I3KKU2_ORENI AEQEGRTSIMPGRPSRRTPKNCTAK---------------------------PS---AAS
A0A0F8BBR5_LARCR GKEDASSSQTPRRSS------------------------------------------TKT
H2S3C6_TAKRU AKVASSSS-TPRKTSSTPKTSVPKT---------------------------SSGARASS
W5MUC6_LEPOC DFESGGVSDFPVDVSGIQEQMKLEEQMLKRQ-----------------QQEEEDRLLALK
RN168_XENLA SSDGINVLKPINKQPTILDLFQRSAGK
RN168_XENTR SSEGMNVLKPSNKQPTILDLFQRSAGK
E2R9S2_CANLF VSKSTPSLQPSKSQKSIFQMFQRYTK-
M3XXR6_MUSPF VSKSTNSLQPSKSQKSIFQMFQRYTK-
M3WSK4_FELCA VSKSAHSLQPSKSQKSIFRCFRGIRS-
G1PJQ9_MYOLU VSKSVRSLQPSKSQKSIFQMFQR----
L5L1H7_PTEAL LSKSAHSLQPSKSQKSIFQMFQR----
RN168_BOVIN VSKTAHSLQPSKSQKSIFQMFQRVTK-
W5QGI9_SHEEP VPKTAHSLQPSKSQKSIFQMFQRFTK-
H0WI34_OTOGA VPKSAHSLQSRNSQKSIFQMFQRCSK-
L9JKX5_TUPCH VSKNAHSLQPSNSQKSIFQMFQRYTK-
RN168_HUMAN VSKSAHSLQPSISQKSVFQMFQRCTK-
H2QP09_PANTR VSKSAHSLQPSISQKSVFQMFQRCTK-
H2PCF9_PONAB VSKSAHSLQPSISQKSVFQMFRRCTK-
G1QLL3_NOMLE VSKSAHSLQPSVSQKSVFQMFRRCTK-
A0A096N1J6_PAPAN VSKSAHSLQPSISQKSIFQMFQRCTK-
A0A096MWZ4_PAPAN VSKSAHSLQPSISQKSIFQMFQRCTK-
G7NZ37_MACFA VSKSAHSLQPSISQKSIFQMFQRCTK-
A0A0D9R8C4_CHLSB VSKSAHSLQPSISQKSIFQMFQRSTK-
F7GIE2_CALJA VSRSAHSLQPNISQKSIYQMFHRCTK-
G5ALC0_HETGA VPRSAQSLQPSNSQKSIFQMFHRCTK-
A0A091ECS8_FUKDA VPRSVQSLQPSNSQKSIFQMFRRCT--
RN168_MOUSE VSKSAYTVQHRKSQRSIVQMFQR----
RN168_RAT VSKRACPLQHRSAQKSILQMFQR----
G3GSL5_CRIGR VSKRTYSLQSSNSQKSIIQMFQR----
G3W6K6_SARHA SSKNTHSLRPSNTQKSIFQMFHQAAK-
G3W6K5_SARHA SSKNTHSLRPSNTQKSIFQMFHQAAK-
F6XBK7_MONDO SFKNTRSLQPSNTQKSIFEMFQQAAK-
U3JKI4_FICAL -TNDICSL-PKNKQKTILQMFKSPVA-
G1MW43_MELGA -SNDVHSL-PKRKQKTILQMLKS----
G1KSE8_ANOCA SPGSRSSELLPNKQKTIVQMFKRPATS
RN168_DANRE STAVSSTVKKGTKQTTLTEMFPNMGS-
W5KS43_ASTMX PSTPSSSVQRGAKQTTLTDMFPNMGS-
I3KKU2_ORENI SSSSSSSSGKGSKQTLLTEMFSTLSS-
A0A0F8BBR5_LARCR TKTSSASSSRGSKQTTLTDMFSCLNS-
H2S3C6_TAKRU TTTSSPSVCRGRKQATLTEMFSSFSR-
W5MUC6_LEPOC LQKQLDQESKAVNRKKGSPDEYPFR--
: