CLUSTAL format seed alignment for MF_03067
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
RNF8_HUMAN ------MGEPGFFVTGDRAGGRSWCLRR-VGMSAGWLLLEDGCEVTVGRGFGVTYQLVSK
G3RG85_GORGO ------MGEPGFFVTGDRAGGRSWCLRR-VGMSAGWLLLEDGCEVTVGRGFGVTYQLVSK
G1RK27_NOMLE ------MGEPGLFVTGDRAGGRSWCLRR-VGMSAGWLLLEDGCEVTVGRGFGVTYQLVSK
RNF8_PONAB ------MGEPGFFVTGDRAGGRSWCLRR-VGMSAGWLLLEDGCEVTVGRGFGVTYQLVSK
G7P3D2_MACFA ------MGEPGFFVTGDRARGRSWCLRR-GGMSAGWLLLEDGREVTVGRGFGVTYQLVSK
F7BPC7_MACMU ------MGEPGFFVTGDRARGRSWCLRR-VGMSAGWLLLEDGREVTVGRGFGVTYQLVSK
A0A096NHV0_PAPAN ------MGEPGFFVTGDRAGGRSWCLRR-VGMSAGWLLLEDGREVTVGRGFGVTYQLVSK
A0A0D9RDL7_CHLSB ------MGEPGFFVTGDRAGGRSWCLRR-VGMSAGWLLLEDGREVTVGRGFGVTYQLVSK
H0XEE3_OTOGA ------MGEPDFLVTGDCVGGRSWCLRR-VGMNAEWLLLEDGREVTVGRGFGVTYQLVSK
F1RVS2_PIG ------MGEPGSLVTGGRAGDRSWCLRR-VGMNAEWLLLEDGKEVTVGRGFGVTYQLVSK
I3L6W2_PIG ------MGEPGSLVTGGRAGDRSWCLRR-VGMNAEWLLLEDGKEVTVGRGFGVTYQLVSK
RNF8_BOVIN ------MGDPGSLVTEGRAGERSWCLRR-VGMNTEWLLLEDGNEVTVGRGFGVTYQLVSK
M3YRF5_MUSPF ------MEEPGSLVMGDRAGGRSWCLRR-VGMNAEWLLLEDGNEVTIGRGFGVTYQLVSK
G1MA53_AILME ------MEEPGLLVTGDRARGRSWCLRR-VGMNAEWLVLEEGNEVTIGRGFGVTYQLVSK
E2RKD8_CANLF ------MEEPGSLVTGDRAGGRRWCLRR-ARMNAEWLLLEDGNEVTIGRGFGVTYQLVSK
J9P6M8_CANLF ------MEEPGSLVTGDRAGGRRWCLRR-ARMNAEWLLLEDGNEVTIGRGFGVTYQLVSK
G1PN75_MYOLU ------MGDPGSRARRERPGGRSWCLRR-VGMDAEWLLLEDGSEVTLGRGFGVTYQLVSK
U3KPJ3_RABIT ------MEKPGSLATGLRC--QSWCLRR-VGMNVEWLLLEDGREVSLGRGFSVTYQLVSK
RNF8_MOUSE ------MGEPDPLVSGQLAARRSWCLRR-LGMDCEWLQLEAGTEVTIGRGLSVTYQLISK
RNF8_RAT ------MGEPDPLVSGQLAARRSWCLRR-LGMDREWLQLEAGSEVTIGRGFSVTYQLISK
E1C4A8_CHICK -------------MAACGASRPAWCLRR-VGAGGGWLLLEAGTQVTVGRGLDLTYQLVSK
G1NE57_MELGA ----------MTECSIGITVQLRYCKKRPARSPGEDLHLPPHLEVTVGRGLDLTYQLVSK
A0A0Q3RF81_AMAAE -------------MATRGPSRLAWCLRR-VGASGDWLLLEAGTQVTIGRGLDLTYQLVSK
A0A151P3T7_ALLMI ---------------MAECGGRCWCLRRLG-QHEQWLLLRGGAEVTIGRGLGLTYQLVSK
A0A151P2W8_ALLMI ---------------MAECGGRCWCLRRLG-QHEQWLLLRGGAEVTIGRGLGLTYQLVSK
K7GJT8_PELSI ------LVGPGRLARIQPTGTRKKVLRRPSSEPTAALFLKPGEEVTVGRGFGLTYQLVSK
RNF8B_XENLA --------------MADGGSGMCWCLRR-CGKNQEVLLLPDGEEVTMGRGLGVTYQLKPT
RNF8A_XENLA --------------MTDEGPGMCWCLRR-CGRNTEDLLLPDGEEVTLGRGLGVTYQLKPT
RNF8_DANRE -MEKTEEPPSSNNEEDSPAKEKIWCLQR-VGRDSDWLRLFEDSEVSVGRGLNVTHQILSS
I3IRX0_DANRE -MEKTEEPPSSNNEEDSPAKEKIWCLQR-VGRDSDWLRLFEDSEVSVGRGLNVTHQILSS
W5LR09_ASTMX -METVGED-QKRPEEGDHQDDKVWCLKR-VGKDSGWLRLTEDTEVTIGRGLNVTHQILSV
A0A087YLS4_POEFO -MDSVATD-CCSAEEDDCSDSEVLCLMR-VGKNSDWLRLFENAEITVGRGVEVTHQLLSS
M4ASE8_XIPMA -MEGVTTD-CCSAEEDDCSDSEVLCLMR-VGETSDWLRLFENAEVTVGRGVEVTHQLLSS
G3PJP4_GASAC -MDTVAAD-SSPAEEDESSDSEVLCLKR-VGRNSDWLRLLGNTEIRIGRGLDVTHQLLSP
I3JF49_ORENI MDKETAAD-CCAVEDDECPDSEVFCLMR-VGRNSDWLRLFENTEITIGRGVDVTYQLLSP
H2SP54_TAKRU -MESVATN-SSVAEEEDDGDSDVSCLMR-VGRNSDWLRFYENSEITVGRGLDVTYQLLSP
H2M926_ORYLA -MESTTTE-SCSAEEEDSSDSEVACLMR-VGKKSEWLRLFGNTEVTVGRGVNVTYQLLSA
W5NHZ5_LEPOC -MAEEAESGAVSGEEDDAAKDEIWCLRR-VGKRAEWLRLPEKEEVTLGRSFDVTYQTLSR
* * : :: :**.. :*:* .
RNF8_HUMAN ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLE
G3RG85_GORGO ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLE
G1RK27_NOMLE ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLE
RNF8_PONAB ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLSVYSIHQGDYIQLGVPLE
G7P3D2_MACFA ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLE
F7BPC7_MACMU ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLE
A0A096NHV0_PAPAN ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLE
A0A0D9RDL7_CHLSB ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLE
H0XEE3_OTOGA ICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRERLEPLKVYSIHKGDHIQLGVPLE
F1RVS2_PIG ICPLMISRNHCVLKQNAEGQWTITDNKSLNGVWLNRERLEPLKVYSIHEGDHIQLGVPLE
I3L6W2_PIG ICPLMISRNHCVLKQNAEGQWTITDNKSLNGVWLNRERLEPLKVYSIHEGDHIQLGVPLE
RNF8_BOVIN ICPLMISRNHCILKQNAEGQWTIKDNKSLNGVWLNRERLEPLKVYSIHKGDHIQLGVPLE
M3YRF5_MUSPF ICPLMISRNHCVLKQNVEGQWTIMDNKSLNGVWLNRERLEPLKVYSIHKGDHIQLGVPLE
G1MA53_AILME ICPLMISRNHCVLKQNVQGQWTIMDNKSLNGVWLNRERLEPLKVYSIHKGDHIQLGVPLE
E2RKD8_CANLF ICPLMISRNHCVLKQNVEGQWTIMDNKSLNGVWLNRERLEPLKVYSIHKGDHIQLGVPLE
J9P6M8_CANLF ICPLMISRNHCVLKQNVEGQWTIMDNKSLNGVWLNRERLEPLKVYSIHKGDHIQLGVPLE
G1PN75_MYOLU LCPLMISRNHCVLKQNTEGQWTIMDNKSLNGVWLNRVRLEPLEVYSLHTGDRVQLGVPLE
U3KPJ3_RABIT VCPLMISRKHCVLKQNPEGQWTIMDNKSLNGVWLNRVRLEPLKFYAIHQGDHIQLGVPLD
RNF8_MOUSE VCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRERLAPLQGYCIRKGDHIQLGVPLE
RNF8_RAT VCPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRERLAPLQGYCIRKGDHIQLGVPLE
E1C4A8_CHICK TCPLMISRKHCVFQQNAEGQWTVKDNKSLNGVWLNKQRLDPSKTYPIAEGDRIQLGVPLE
G1NE57_MELGA TCPLMISRKHCVFQQNAEGQWTVKDNKSLNGVWLNKQRLDPSKTYPLAEGDRIQLGVPLE
A0A0Q3RF81_AMAAE TCPLMISRKHCIFQQNAEGQWTVKDNKSLNGVWLNKQRLXPSKAYPIAEGDRIQLGVPLE
A0A151P3T7_ALLMI ICPLMISRNHCVFKQNEEGQWTVKDNKSLNGVWLNKERLDPLKAYPIVEGDHIQLGVPLE
A0A151P2W8_ALLMI ICPLMISRNHCVFKQNEEGQWTVKDNKSLNGVWLNKERLDPLKAYPIVEGDHIQLGVPLE
K7GJT8_PELSI TCPLMISRYHCAFKQNAQGQWTVTDNKSLNGVWLNKERLDPFKAYTIGEGDHIQLGVPLD
RNF8B_XENLA LCPLMISRTHCLFKQNARDEWTVTDNKSLNGVWRNKERLEPHKAYTLSEGTLIQLGVPPP
RNF8A_XENLA LCPLMISRTHCLFKQNTGGEWTVTDNKSLNGVWRNKERLEPHKAYTLSEGALIQLGVPPP
RNF8_DANRE SCPLMISRIHCVFKLNEGRQWTVTDNKSLNGVWVNGKRIPPSTPCILHQSDSVRLGVPLD
I3IRX0_DANRE SCPLMISRIHCVFKLNEGRQWTVTDNKSLNGVWVNGKRIPPSSPCILHQSDSVRLGVPLD
W5LR09_ASTMX SCPLMISRNHCMLKQKEDGQWTVTDNESMNGVWVNGVRISARKPYTLQQDDVVRFGVPLD
A0A087YLS4_POEFO TCPLMISRLHCSFRQKEDGQWTVTDKKSLNGVWVNGERIPAEQPHLLRLGDSIQLGVPLL
M4ASE8_XIPMA TCPLMISRLHCSFRQKEDGQWTVTDKKSLNGVWVNGERIPAEQPHLLQLGDSIQLGVPLL
G3PJP4_GASAC SCPLMISRLHCTVRQREDGQWTVTDEKSLNGVWVNGNRIPAEEAHQLRLGDSIQLGVPVT
I3JF49_ORENI ACPLMISRLHCTFKQSEDGHWTVTDKKSLNGVWVNGTRLPSDESRQLRLGDSIQLGVPVI
H2SP54_TAKRU SCPLMISRLHCTFRQRDDGQWTVTDKKSLNGVWVNGSRIPAEEAHQLKLGDSIQLGVPII
H2M926_ORYLA SCPLMISRLHCTFKRKEDGQWTVTDKKSLNGVWVNGNRIPADEAHLLRPGDSIQLGVPVM
W5NHZ5_LEPOC SCPLMISRNHCKFKQNEEGHWTVTDNKSLNGVWVNGLRITPERTHTLHVGDTIQLGVPLG
******* ** .: .**: *::*:**** * *: . : . :::***
RNF8_HUMAN NKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLK
G3RG85_GORGO NKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLK
G1RK27_NOMLE NKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLK
RNF8_PONAB NKENAEYEYEVTEEDWETIYPCLSPKNDQVIEKNKELRTKRKFSLDELAGPGAEGPSNLK
G7P3D2_MACFA NKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDQLGGPGAEGPSNLK
F7BPC7_MACMU NKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDQLGGPGAEGPSNLK
A0A096NHV0_PAPAN NKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDQLGGPGAEGPSNLK
A0A0D9RDL7_CHLSB NKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDQLGGPGAEGPSNLK
H0XEE3_OTOGA NKENAEYEYEVTEEDWERIYPCLFPKDDQMIDKNKSLRTKRKFSLDE--GSGAEGPSNLK
F1RVS2_PIG NKENAEYEYEVTEDDWERVYPCLSLKSDQMMEKNKGLRTKRKFNLDELEGSGAEGPSTLK
I3L6W2_PIG NKENAEYEYEVTEDDWERVYPCLSLKSDQMMEKNKGLRTKRKFNLDELEGSGAEGPSTLK
RNF8_BOVIN NKENAEYEYEVTEEDWERIYPCLSPKSDQMMEKNKGLRTKRKFSLDELEGSGAEGPSNLK
M3YRF5_MUSPF NKENAEYEYEVTEEDRERMYPCLAPKNDQMTGKNRGLRTKRKFSLDELEGPGAEGPSNLK
G1MA53_AILME NKEKAEYEYEVAEEDRERMYPCLAPKNDQMTGKNRGLRTKRKFSLDELEGPGAEGPSTLK
E2RKD8_CANLF NKENAEYEYEVTEEDWERMYPCLAPKNDQIIGKNRGLRTKRKFSLDELEGPGAEGPSHLK
J9P6M8_CANLF NKENAEYEYEVTEEDWERMYPCLAPKNDQIIGKNRGLRTKRKFSLDELEGPGAEGPSHLK
G1PN75_MYOLU NKESAEYEYEVTEEDWEKMCPYLAPKNDQILGKNKGLRTKRKCSLDELEGPEAEGPSHLK
U3KPJ3_RABIT NKENAEYEYEVSEEDWEQVVPRLALKCKQMMEKNKSLRTKRKFSLDELEGSGAEGPSNLK
RNF8_MOUSE SRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGSRTKRKFSSPGLENLPAEGSSDLR
RNF8_RAT SKEHAEYEYEVIEEDRESLAPCLAPKNDHTTEKHKGLRTKRKFSSDGVESLPAEGPSDLR
E1C4A8_CHICK NKETAEYEYEVIKEEWEKIRPFLAQRSD--LGKARSSRSKRKFTSEESETSGSEGPSNSR
G1NE57_MELGA NKETAEYEYEVIKEEWEKIRPFLAQRSD--LGKAKSSRSKRKFTLEESETSGSEGPSNSR
A0A0Q3RF81_AMAAE NKESAEYEYEVIKDEWEKIRPFLAQRSD--LGKAKTSRTKRKICPEEFETSASEGPSNSR
A0A151P3T7_ALLMI SKEAAEYEYEVIREEWEKISPFLAPRNDQVMGKSKSTRTKRKFSLEESEALGAEGPSNSR
A0A151P2W8_ALLMI SKEAAEYEYEVIREEWEKISPFLAPRNDQVMGKSKSTRTKRKFSLEESEALGAEGPSNSR
K7GJT8_PELSI NKETAEYEYEVIKEEWEKVCPFLAPRNDQVMGKAKGARTKRKLSLEESEASGAEGPSDSR
RNF8B_XENLA NMESAEFEYILVREHLDKVSGSLI---RPLPGKTKATRTKRKFPSEDADASGNEGPSNFS
RNF8A_XENLA NMESAEFEYMLVREHLEKLSGSLI---RPLPDKTKATRTKRKFTSEDTDASGNEGPSNFS
RNF8_DANRE GNP-VEFDYILVQKNFDDVKSFLSGNLGKDSGAA-SLSQKLKNSKRKFDGGDESEPCPTQ
I3IRX0_DANRE GNP-VEFDYILVQKNFDDVKSFLSGNLGKDSGAA-SLSQKLKNSKRKFDGGDESEPCLTQ
W5LR09_ASTMX SNP-VEFEYVLIHQSLSKIKDFLTKAVVAEAGPN-ASALKPKKSKRKF-GTDEAEPGTTL
A0A087YLS4_POEFO GTK-VEFDYILIQRPLKDIKPYLVKE--QREDTK-AAHTP-RKFKRKL-GVEEVEPSTSK
M4ASE8_XIPMA GTK-VEFDYILIQRPLKDIKPYLVKE--HREDTK-AAHTP-RKFKRKL-GVEEVEPSTSK
G3PJP4_GASAC GTE-VEFDYVLVQRPLRDIKHYLARG--HKESPK-AAPVS-KKSKRKW-SVEEVEPSTSK
I3JF49_ORENI GNK-AEFDYVLVQEPLRDIKCFLAKKLVERVTSK-SAHIS-KKPKRKL-TMEEVEPSTSK
H2SP54_TAKRU GSE-VEFNYVLVKRPLKDIKEFFLKG--PKDSPK-VVILP-KKPKRKL-VVEEVEPSTSK
H2M926_ORYLA GSK-VEFDYVLVQQPLKDIKLHLAKT--HKEGAT-AAAIT-ESSKRKM-TMEEDEPSTSK
W5NHZ5_LEPOC GKE-VEFEYVLVRDCLKSVKPFLLKE---PVEEE-AAGSRLKRTKRKY-SGGELDPGNTS
. .*::* : . : : . .
RNF8_HUMAN ---SKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTALEPSK-TTGAPIYPGF---PK
G3RG85_GORGO ---SKINKVSCESGQSVKSQGKGEVASTPSENLDPKLTALEPSKKTTGAPIYPGF---PK
G1RK27_NOMLE ---SKINKVSCESGQSVKSQGKGEVASTPSENLDPKLTALEPSKKTTGAPIYPGF---PK
RNF8_PONAB ---SKINKVSCESGQSVKSQGKGEVSSTPSENLDPKLTVLEPSKKTTGAPIYLGF---PK
G7P3D2_MACFA ---SKINKVSCESSQSVKSQGKGEVASTPSENLDPKLTALEPSTKTTGAPIYPGF---PI
F7BPC7_MACMU ---SKINKVSCESSQSVKSQGKGEVASTPSENLDPKLTALEPSTKTTGAPIYPGF---PI
A0A096NHV0_PAPAN ---SKINKVSCESSQSVKSQGKGEVASTPSENLDPKLTALEPSKKTTGAPIYPGF---PI
A0A0D9RDL7_CHLSB ---SKINKVSCESSQSVKSQGKGEVASTPSENLDPKLTALEPS-KNTGAPIYPGF---PI
H0XEE3_OTOGA ---SKISKVSCKIGQLVKSHGKGEVSNQLSECLDPKLTSLEPNEKNTRTHVYSGL---PE
F1RVS2_PIG ---SKISKVSCEPGQPVKSHEKGKVAGQLNEYLDPKLTCLQPSGKALGAHVYPVP---AK
I3L6W2_PIG ---SKISKVSCEPGQPVKSHEKGKVAGQLNEYLDPKLTCLQPSGKALGAHVYPVP---AK
RNF8_BOVIN ---SKISKLSCEPGQQVKSHGKGKVASQPSEYLDPKLTSFEPSVKTTGAHVNPGP---AK
M3YRF5_MUSPF ---SKISKVSCEPGQPVKSHGKGEVASQPAEYLDPKLTSVEPSEKTTEAHVYPGS---AK
G1MA53_AILME ---SKMSKVSCEPGQPVKSHWKGEAASQPSEYLDPKWTSLEPKEKATEARVHPGF---AK
E2RKD8_CANLF ---SKISKVSYKPGQPVKSHGKGEVASQPSEYLDPKLTSLELSEKATDAHVYPSS---TK
J9P6M8_CANLF ---SKISKVSYKPGQPVKSHGKGEVASQPSEYLDPKLTSLELSEKATDAHVYPSS---TK
G1PN75_MYOLU ---FKMNKVSSEPGQPLRSRGKGELASGPSEHWEPRVTSLEPSENVSGAHVFSGP---TK
U3KPJ3_RABIT ---SKMNEMSCEPGQPVQSHENGKVASLPSKYLDPKLTSPEAQEKVSGADVYSTP---PK
RNF8_MOUSE ---CPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSLKASERAAGPHACSAL---PK
RNF8_RAT ---CPLAKGSSKPAEPEKLHGKGEAASQPLGCLCPTLASLEASERTAGPHACSTL---PK
E1C4A8_CHICK ---SKRDRVSCDGEPLSNLLGRVGEAKQLTDKVDVKLPSPGSS-EGDGGLVRGSLDCSEK
G1NE57_MELGA ---SKRDRVSCDGEPLSNLLRRVGETKQLTDKMDVKLPSPGSS-EDDGGPVHRTPDCSEK
A0A0Q3RF81_AMAAE ---SKRDRVSFDNELVGKSWGRIEEVKQFTDKMDVKLPSPGPS-EEDRHPVCSGPVHPEK
A0A151P3T7_ALLMI ---SKRD--KVHSEPLIKPWEMAELAKQPTENMDLKLPSPGTSEEEEKAPVYCGPLQPEK
A0A151P2W8_ALLMI ---SKRD--KVHSEPLIKPWEMAELAKQPTENMDLKLPSPGTSEEEEKAPVYCGPLQPEK
K7GJT8_PELSI ---SKRDRVSCDSEPLSKSQERAELAKQQTENMDVKLPSPGPSMEEDDAPMYCIPVNSEK
RNF8B_XENLA I--PKFCRVSRDGEDSAKSLRTSHK--------QPKASGVEPELNDSVETDTVSP-----
RNF8A_XENLA I--PKFYRVSREDEDSAKSSHTTDLYKQPT--VEPTASGTESRLNDSVEAEVVAP-----
RNF8_DANRE HSKSKLYRSSAPD----KSRAQPCPSGERRETLKLSSRPLEEDR----DKAGSSS-----
I3IRX0_DANRE HSKSKLYRSSAPD----KSRAQPCPSGERRETLKLSSRPLEEDR----DKAGSSS-----
W5LR09_ASTMX DSRCKLYRSSATD----KASAQPCPT----------DIPACRWP----DDPPGSS-----
A0A087YLS4_POEFO H---KLYRCSSAD----KSFAKPCPLSPVKARRQLSHTQPEETV----TSIQENEG----
M4ASE8_XIPMA H---KLYRCSSAD----KSFAKPCPLSPVKARRQLSHTQPEETV----TGRKEHEG----
G3PJP4_GASAC P---KLYRCSSAD----KSFAKPCPASPAQRQPRLAHSQSEETG----TSRQVQEV----
I3JF49_ORENI P---KLYRCSSAD----KSLAVPCPLFLLKGQQRLSHTKPEGTG----PGRDDRQA----
H2SP54_TAKRU P---KLYRCSSAG----KTFAKACPLSPVKCKQKLGHIQTQQCG----ASRGAQEV----
H2M926_ORYLA P---KLYRRSSSD----KSLAKACPPPLKKCQLQQSRSQPEETA----SGRRVQES----
W5NHZ5_LEPOC DAKAKLSRWSHAEP---QPQGSSCAAVQQPPVQNIQTAEPAGPSRTPPSSPAAAGG----
.
RNF8_HUMAN VTEVHH--EQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKG---N
G3RG85_GORGO VTEVHH--EQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKG---N
G1RK27_NOMLE VTEVHH--EQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKG---N
RNF8_PONAB VTEVHH--EQTASNSSASQRGLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKG---N
G7P3D2_MACFA VTEVHH--EQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKG---N
F7BPC7_MACMU VTEVHH--EQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKG---N
A0A096NHV0_PAPAN VTEVHH--EQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKG---N
A0A0D9RDL7_CHLSB VTEVHH--EQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKG---N
H0XEE3_OTOGA VLELHH--KEKASNPSTSQSSLELFKVTMSRILKLKTQMHEKQLAVLNVKKQTPKG---S
F1RVS2_PIG VVELQHR-KQKASNPSASQSSLELFKVTMSRILKLKTQMQEKQIAVLNVKKQTQKG---N
I3L6W2_PIG VVELQHR-KQKASNPSASQSSLELFKVTMSRILKLKTQMQEKQIAVLNVKKQTQKG---N
RNF8_BOVIN VIELLRK-KKKASNPSASQSSLELFKVTMSRILMLKTQMQEKQVAVLNVKKQTKKG---S
M3YRF5_MUSPF VIELHHK-KQKASNPSVSQSSLELFKVTMSRILKLKTQMQEKQVAVLKVKKQTQKG---N
G1MA53_AILME VIELHHK-KQKASNPTACQSSLELFKVTMSRILKLKTQMQEKQVDVLKVKKQTQKG---N
E2RKD8_CANLF VVALHHK-KQKASSPSASQSSLELFKVTMSRILKLKTQMQEKQVAVLNVKRQTQKG---N
J9P6M8_CANLF VVALHHK-KQKASSPSASQSSLELFKVTMSRILKLKTQMQEKQVAVLNVKRQTQKG---N
G1PN75_MYOLU VLALHHH-KRKASNLSVSQSRLELFKVTMSRILKLKTQMQEKQVAVLNEKKQTQKG---D
U3KPJ3_RABIT IIAPHHN-KQKGSNPSTSQSSLELFKMTMSRILKLKTELQEKQIAVLNVKRQTQKG---N
RNF8_MOUSE VLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQIAVLNVKRQTRKG---S
RNF8_RAT VLEL-YPKKQKACSPSASQSSLELFKMTMSRMLKLKTQMQEKQIAVLNVKRQARKG---S
E1C4A8_CHICK AVAIAHE-DQKHSALSQSWTDLENLRKTLIDIKKLKVKVQEKQTAVLTAKQKRRKA---A
G1NE57_MELGA AVAVAHE-DQKHSVLSQSWTGLEKLRKTLIDIKQLKVKVQEKQTAVLNAKQKRRKA---A
A0A0Q3RF81_AMAAE AVSALHK-DQKGSGLAESWTGLEKLRKTLVDITELKVKVQEKQAAVLNVKQKRRKC---A
A0A151P3T7_ALLMI ALSLGHR-DQKAPSLAQSWTSLEMLKKTLVDIMKLKVKVQEKQTAVLSMKQKSRKS---A
A0A151P2W8_ALLMI ALSLGHR-DQKAPSLAQSWTSLEMLKKTLVDIMKLKVKVQEKQTAVLSMKQKSRKS---A
K7GJT8_PELSI AVSLRHK-DQKASSLAQSWTGLEMLRKTLGDIMKLKVKMEEKKTAILSVR-KSRKS---G
RNF8B_XENLA --------TQQQCC--RSTLQLSRVRETMEEIRRLNVQIQEKQIKMQEKLNHPQESQ-LG
RNF8A_XENLA --------TQQQC---RSTLQLSRVRQTMEEIRRLNVQMQEKQMEMQEKLNSPLENQ-VG
RNF8_DANRE ------------STCSDSSQHLATLHRYNRSLMVLKGRVGDTQKRAAELEQQQTQT-PER
I3IRX0_DANRE ------------STCSDSSQHLATLHRYNRSLMVLKGRVGDTQKRAAELEQQQTQT-PER
W5LR09_ASTMX ------------ADCSNSSQQLATLRRYNNNLRALRDRMGATQKQAAELEGQENTS-PEQ
A0A087YLS4_POEFO --------ELPPPDGSSSAWDLDNLQMYSQNILLLREQVSDTQRQVESLEGEPRQADPLR
M4ASE8_XIPMA --------ELPPSDGSSSVWDLDNLQMYSQNILLLREQVSDTQRQVESLEGEPRQADPLR
G3PJP4_GASAC --------DRP-SDGSNSPCDLDELQMYSQNILRLREQVDDTQRQVASLGGAPQRAHPLR
I3JF49_ORENI --------ERP-SDGSSATRDLDNLQMYSQNILLLREQVDDTQRHVASLEGEPRQADPLR
H2SP54_TAKRU --------DQP----SHILCDTDNLQTYSQNILILRRQVDSTQKQVESLGEEPQQTDPLR
H2M926_ORYLA --------RQR-SDGSQPPC--DNLQMYSQNILLLREQVDDTQRRVASLEGEDQQGDPLV
W5NHZ5_LEPOC --------SEKPQKNAHCSSELACFQRYIRKMRVLKKKVQETERRAASLQAQPVPP----
.: : *. .: ..
RNF8_HUMAN SKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEIAQGEKDLKQQL
G3RG85_GORGO SKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEIAQGEEDLKQQL
G1RK27_NOMLE SKKIVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEIAQGEEDLKQQL
RNF8_PONAB SKKIVQMEQELLDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQDLEIAQGEEDLRQQL
G7P3D2_MACFA SKKIVRMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEIAQGEEDLKQQL
F7BPC7_MACMU SKKIVRMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEIAQGEEDLKQQL
A0A096NHV0_PAPAN SKKIVRMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLETAQGEEDLKQQL
A0A0D9RDL7_CHLSB SKKIVRMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEIAQGEEDLKQQL
H0XEE3_OTOGA SKKIVKMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEKEQGEEDLKQQL
F1RVS2_PIG SKKIVKMEQELHDLQSQLCAEQAQQQARVEQLEKTFQEEQQH-LQGLEKEQGEEDLKQQL
I3L6W2_PIG SKKIVKMEQELHDLQSQLCAEQAQQQARVEQLEKTFQEEQQH-LQGLEKEQGEEDLKQQL
RNF8_BOVIN SKKIVKMEQELQDLQSQLCAEQAQQQARVEQLEKTIQEEQQH-LEGLEKEEGEEDLKQQL
M3YRF5_MUSPF SKKIVKMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEKEQGEEDLKQQL
G1MA53_AILME SKKIVKMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGWEKEQGEEDLKQQL
E2RKD8_CANLF SKKIVKMEKELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEKDQGEEDLKQQL
J9P6M8_CANLF SKKIVKMEKELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQH-LQGLEKDQGEEDLKQQL
G1PN75_MYOLU SKNIVQMEQELQDLQSQLCAEQAQQEARVEQLEKTFEEEQQY-LQGLEKEQGEEDLKQQL
U3KPJ3_RABIT SKTIVKMEEELQALQSQLCAEQAQQQARMEELEKTFQEEEQH-LQDLEKEQGEEDLKQQL
RNF8_MOUSE SKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHY-LQGLEKEQGECDLKQQL
RNF8_RAT SKKVVRMEKELRDLQSQLYAEQAQQQARVEQLEKTFQEEEQH-LQGLEKEQGECDLKQQL
E1C4A8_CHICK QKTILAMEKELQELQDKLRTEQVQHQQQVEELERTFCKEKQK-LEGVKWKDGEENLKEQL
G1NE57_MELGA QKTILAMEKELQELQDKLCTEQVQHQQQVEELERTFSKEKQE-LEGVKWQDGEENLKEQL
A0A0Q3RF81_AMAAE QKDILAMEQELQQLQNQLCMEQEHHQQQVEELKRTFCKEQQN-LEGVKGQHGEENLKEQL
A0A151P3T7_ALLMI RKEIMVMEKELQELQEQLCTEQEQHQQRVEQLEKMFCGEQEQ--EGVKQEQGDESLKEQL
A0A151P2W8_ALLMI RKEIMVMEKELQELQEQLCTEQEQHQQRVEQLEKMFCGEQEQ--EGVKQEQGDESLKEQL
K7GJT8_PELSI QKEIKVMEQELQELQNQLCTEQEHQQQRVEQLERTFYEEQQQLLEGVKKQQGEENLKEQL
RNF8B_XENLA SNSYLVVQKELQALRNQLSNEQEQHLQSVKELKEIFQEEQQS--MGSQKQAEEEHLKEQL
RNF8A_XENLA ANSVLAVQKELRALHNHLSNEQEQHMQSVKELKEIFEEEQQS--MGSRKQVEEEHLKEQL
RNF8_DANRE EKEMQDLQTQLEALRGQLRSQQEQALRRMETLEKSFCEEERR-LETEKAQQNEVGLKKQL
I3IRX0_DANRE EKEMQDLQTQLEALRGQLRSQQEQALRRMETLEKSFCEEERR-LETEKAQQNEVGLKKQL
W5LR09_ASTMX QRKMLELQEQMEVLQGQLNSQHEMALQRVNMLEKSVCEEERR-LEVTKAQQKEDGLKKQL
A0A087YLS4_POEFO GEQVRELQGQLEALRAKM--------HRMETLEKSFSETKRQ-LEEQKTQQQEELMKKQL
M4ASE8_XIPMA GEQVRELQGQLEALRAKM--------HRMETLEKSFSETKRQ-LEEQKTQQQEELMKKQL
G3PJP4_GASAC EEHVRELQAQLETLRAKM--------HRMETLEKSFSRTKRQ-LEAQKTKQQEEHLKKQL
I3JF49_ORENI EEQVRELRGQLDTLRAKM--------HRMETLEKSFSETKRL-LEEQKTQQQEELLKKQL
H2SP54_TAKRU EVQVRELQAQLETLRSKM--------HQMEALERSFSQTQQQ-LEAQKTQQEEKLMKKKL
H2M926_ORYLA RERVQELQSQLGTLRGKM--------HQMETLKKSFSE-RRW-PEHQKTQQ-EEQMRKQL
W5NHZ5_LEPOC SEELEQLQGRLEVLKEQLHSEQQQQLRRVEQLEKTFCEEERR-LEDEKKQQEEESLNKKL
:. .: *: :: :: *:. . . . : :.::*
RNF8_HUMAN AQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENE
G3RG85_GORGO AQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
G1RK27_NOMLE AQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
RNF8_PONAB AQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
G7P3D2_MACFA AQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
F7BPC7_MACMU AQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
A0A096NHV0_PAPAN AQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
A0A0D9RDL7_CHLSB AQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
H0XEE3_OTOGA AQALQEHRALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMTDVLENE
F1RVS2_PIG AQALQEHRALMEELNRSRKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
I3L6W2_PIG AQALQEHRALMEELNRSRKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
RNF8_BOVIN AQALQEYRSLVEELNRSKKNFEAIIQAKDKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
M3YRF5_MUSPF AQALQEHRALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHVNDVLENE
G1MA53_AILME AQALQEHQALTEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
E2RKD8_CANLF AQALQEHRALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHVNDVLENE
J9P6M8_CANLF AQALQEHRALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHVNDVLENE
G1PN75_MYOLU AQALQEHQALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHMNDVLENE
U3KPJ3_RABIT VQALQEHRALMEELNRSKKDFEAIIQAKNRELEQTKEEKEKVQAQKEEVLSQMNDVLENE
RNF8_MOUSE VQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKEEVLSHMNDLLENE
RNF8_RAT LQALQEHRALMEELDRSKKDFEKIIQAKNKELERTKEEKDKVQAQKEEVLSHMNDVLENE
E1C4A8_CHICK AQVLQEHHALMEELSRSKKDFEEIIRAKNKELEETKVEKEKVRAQKEEVLNQMNDVLENE
G1NE57_MELGA AQVLQEHHALMEELSRSKKDFEEIIRAKNKELEETKVEKEKVRAQKEEVLNQMNDVLENE
A0A0Q3RF81_AMAAE AQVLQEHHALMEELSRSKKDFEEIIQAKNKELEETKEEKEKVRAQKEEVLNQMNDVLENE
A0A151P3T7_ALLMI AQVLQEHRALMEELSRSKKDFEEKIQAKNKELEETKEEKEKVRAQKEEVLSQMNDVLENE
A0A151P2W8_ALLMI AQVLQEHRALMEELSRSKKDFEEKIQAKNKELEETKEEKEKVRAQKEEVLSQMNDVLENE
K7GJT8_PELSI AQVLQEHRALMDELSRSKKDFEEIIQAKNKELEETKEEKEKARAQKEEVLSQMNDVLENE
RNF8B_XENLA AQALQEHTQLMQELNRNKNDFEQIIQAKNKELQETKEEKEKVCAQKEEVLNHMNDVLDNE
RNF8A_XENLA AQALQEHTQLMQELNRSKNDFEQIIEAKNKELQETKEEKEKVFAQKEEVLNHMNDVLDNE
RNF8_DANRE EEALKEHRKVIEELKHAWQGFKEVLQAKDKELEVTKEEKEKAKAQKEEVVTQMTEVLESE
I3IRX0_DANRE EEALKEHRKVIEELKHARQGFKEVLQAKDKELEVTKEEKEKAKAQKEEVVTQMTEVLESE
W5LR09_ASTMX EEALKEHRKVIEELQHARQGFKEVLQAKDKELEVTKEEKEKARAQKEEVVTQMTEVLENE
A0A087YLS4_POEFO EEALQEQKKVIDELALSRKGFEEIILAKNKELEVTKEEKEKARAQKEEVVTQVTEVLENE
M4ASE8_XIPMA EEALQEQKKVIDELALSRKGFEEIILAKNKELEVTKEEKEKARAQKEEVVTQVTEVLENE
G3PJP4_GASAC EEALQEQKKVIDELAHSREGFEEILLAKNKELELTKEEKEKARAQKEEVVTQVTEVLENE
I3JF49_ORENI EEALQEQKKVIGELALSRQGFEEILLAKNKELEVTKEEKEKARAQKEEVVTQVTEVLENE
H2SP54_TAKRU QDALQEQKKVIDELALSRQAYEEILFAKNKELEVTKEEKEKACAQKEEVVTQVTEVLENE
H2M926_ORYLA NDALQEQKKVIVEHALSRQAFEKILSAKNKELEATKEEKERARAQKDEVVTQMTEVLENE
W5NHZ5_LEPOC DDALQKHRQVIEELRRSRKDFEEIIQAKDKELEETKEAKEKARAQKEEVLTQMAEVLENE
:.*:: : * : :: : **::**: ** *:: ***:**:.:: ::*:.*
RNF8_HUMAN LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKM
G3RG85_GORGO LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKM
G1RK27_NOMLE LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKHIKSKTYSLVLDNCINKM
RNF8_PONAB LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKM
G7P3D2_MACFA LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIESKTYSLVLDNCINKM
F7BPC7_MACMU LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIESKTYSLVLDNCINKM
A0A096NHV0_PAPAN LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIESKTYSLVLDNCINKM
A0A0D9RDL7_CHLSB LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIESKTYSLVLDNCINKM
H0XEE3_OTOGA LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIESKTHSLVLDNCINKM
F1RVS2_PIG LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTHSLVLDNCINKM
I3L6W2_PIG LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTHSLVLDNCINKM
RNF8_BOVIN LQCIICSEYFVEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTRSLVLDNCISKM
M3YRF5_MUSPF LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTHSLVLDNCINKM
G1MA53_AILME LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTHSLVLDNCINKM
E2RKD8_CANLF LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTHSLVLDNCINKM
J9P6M8_CANLF LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTHSLVLDNCINKM
G1PN75_MYOLU LQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTPSLVLDNCISKM
U3KPJ3_RABIT LQCIICSEYFIEAVTLNCAHSFCSYCIKEWMKRKIECPICRKDIESKTYSLVLDNCINKM
RNF8_MOUSE LQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESRTNSLVLDNCISKM
RNF8_RAT LQCIICSEYFIEAVTLNCAHSFCSFCISEWMKRKVECPICRKDIESRTNSLVLDNCISKM
E1C4A8_CHICK LQCTICSEHFIEAVTLNCAHSFCSYCIDEWTKRKVECPICRQEIKSKTRSLVLDNCIDRM
G1NE57_MELGA LQCTICSEHFIEAVTLNCAHSFCSYCIDEWTKRKVECPICRQEIKSKTRSLVLDNCIDRM
A0A0Q3RF81_AMAAE LQCTICSEHFIEAVTLNCAHSFCSYCINEWTKRKVECPICRQEIKSKTRSLVLDNCIDRM
A0A151P3T7_ALLMI LQCTICSEHFIEAVTLNCAHSFCSYCINEWMKRKVECPICRRGIESKTRSLVLDNCIDRL
A0A151P2W8_ALLMI LQCTICSEHFIEAVTLNCAHSFCSYCINEWMKRKVECPICRRGIESKTRSLVLDNCIDRL
K7GJT8_PELSI LQCTICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRREIQSKTRSLVLDNCIDRM
RNF8B_XENLA LQCIICSEHFIEAVTLNCAHSFCSYCIKSWRKRKEECPICRQEILSETRSLVLDNCIDSM
RNF8A_XENLA LQCIICSEHFIEAVTLNCAHSFCSYCIKSWKKRKEECPICRQEIVTETRSLVLDNCIDSM
RNF8_DANRE LQCSICSELFIEAVTLNCAHSFCQHCISEWRNRKDKCPMCWQNITSQTRSLVLDNCIDRM
I3IRX0_DANRE LQCSICSELFIEAVTLNCAHSFCQHCISEWRNRKDKCPMCWQNITSQTRSLVLDNCIDRM
W5LR09_ASTMX LQCIICSELFIEAVTLNCAHSFCLHCISDWRRRKDECPICRQAILSQTRSLVLDNCIDRM
A0A087YLS4_POEFO LQCIICSELFIEAVILNCAHSFCSYCIKQWRNKKDECPICRQAIQSQTRCLALDNCIDRM
M4ASE8_XIPMA LQCIICSELFIEAVILNCAHSFCCYCIKQWRNKKDECPICRQAIQSQTRCLALDNCIDRM
G3PJP4_GASAC LQCIICSELFIEAVILSCAHSFCSHCIKQWRRKKDECPICRRAIQSQTRCLALDNCIDSM
I3JF49_ORENI LQCIICSELFIEAVILNCAHSFCCYCINQWRKKKDECPICRQAIQSQTRCLALDNCIDRM
H2SP54_TAKRU LQCIICSELFIEAVILNCAHSFCCYCIKQWRKKKDECPICRQAILSQTRCLALDNCINSM
H2M926_ORYLA LQCIICSELFIEAVTLNCAHSFCSYCITQWRKKKEECPICRQAITSQSRCLALDNFIERM
W5NHZ5_LEPOC LQCIICSEYFIEAVTLNCAHSFCLHCIMDWRRRKDECPICRQGVVSLTRSLVLDNCIDRM
*** **** *:*** *.****** .** .* .:* :**:* : : : : .*.*** *. :
RNF8_HUMAN VNNLSSEVKERRIVLIRERKAKRLF-----------------------------------
G3RG85_GORGO VNNLSSEVKERRIVLIRERKAKRLF-----------------------------------
G1RK27_NOMLE VNNLSSEVKERRIVLIRERKAKRLF-----------------------------------
RNF8_PONAB VNNLSSEVKERRIVLIRERKVKRLF-----------------------------------
G7P3D2_MACFA VNNLSSEVKERRIVLIRERKGEWV------------------------------------
F7BPC7_MACMU VNNLSSEVKERRIVLIRERKAKRLF-----------------------------------
A0A096NHV0_PAPAN VNNLSSEVKERRIVLIRERKAKRLF-----------------------------------
A0A0D9RDL7_CHLSB VNNLSSEVKERRIVLIRERKAKRLF-----------------------------------
H0XEE3_OTOGA VDNLSSEVKERRIVLTRERKGRRVQ-----------------------------------
F1RVS2_PIG VDNLSSEVKERRVVLIKERKDQRVF-----------------------------------
I3L6W2_PIG VDNLSSEVKERRVVLIKERKVSLKTL----------------------------------
RNF8_BOVIN VDNLNSEVKERRIVLIRERKGKRLF-----------------------------------
M3YRF5_MUSPF VDNLSSEVKERRIVLIRERKGKWVF-----------------------------------
G1MA53_AILME VDNLSSEVKERRIVLTRERKG---------------------------------------
E2RKD8_CANLF VDNLSSEVKDRRIVLIRERKGMRMH-----------------------------------
J9P6M8_CANLF VDNLSSEVKDRRIVLIRERKAKRLS-----------------------------------
G1PN75_MYOLU VDNLSSEVKERRTDLIKRRKGVKDVI----------------------------------
U3KPJ3_RABIT VDNLSSEVKERRIALIRERKAKRLS-----------------------------------
RNF8_MOUSE VDNLSSDVKERRSVLIRERRAKRLS-----------------------------------
RNF8_RAT VERLSSDVKERRSVLIRERRAKRLL-----------------------------------
E1C4A8_CHICK VENLDVEMKEHRLTLIRERKEKRDMLVNPAADNDSSIIPSIYSILSISSCDSEDSEEDFY
G1NE57_MELGA VENLDVEMKEHRLSLIRERK----------------------------------------
A0A0Q3RF81_AMAAE VEKLDVEMKEHRLTLIRERTEKQNVLGKTATDNDSSVTSPIHSILSMSSCDREDSEEDSY
A0A151P3T7_ALLMI VENLSLEMKERRLALIRERKEKQDILVNPATDSESSIVSSIYSILSMSSYDSDDFEEDSD
A0A151P2W8_ALLMI VENLSLEMKERRLALIRERKD-------PPW-----------------------------
K7GJT8_PELSI VENLNLEMKEHRLALIRERKG-------ERWVEKV-------------------------
RNF8B_XENLA VDKLSPEMKNRRAALILERKEMVQAEESNPVLVVSDSSSFLSDTFYISSSSSDSDELGSD
RNF8A_XENLA VDKLSPEMKNRRAALILERKEMVQAEESNPVLVVSDSSSFLSDTFYISSSSSDSDELGND
RNF8_DANRE VENLSADMRERRLVLINERKG----------------------ERSKSESISS-------
I3IRX0_DANRE VENLSADMRERRLVLINERKGLK---------VRASPAVVVINDDSDSEDSSS-------
W5LR09_ASTMX VENLSAEMRERRVALIRERKG------------QSKAPVAVVVIQDDSSSSSS-------
A0A087YLS4_POEFO VENLSLDMKARRQALVTERK------------AAAIAEVMVIHDDDSSRTSDS-------
M4ASE8_XIPMA VENLSLDMKARRQTLITERK------------GMSSSQKVVFTHDGHE------------
G3PJP4_GASAC VKNLSLDMKSRRQTLITERK------------ADA-AQVTVIHDDDSSRSSDS-------
I3JF49_ORENI VENLSLDMKARRQTLISERKDKRAVDHEVIRSAAESAEVMVIPDDDSSSDSNSNSNSSSD
H2SP54_TAKRU VENLSLDMKARRQTLIAERK----------------GESKRTKNKTMSNSSGEM------
H2M926_ORYLA MENLSLDVKEKRQSVINERK----------------GER---------------------
W5NHZ5_LEPOC VENLSSEMKERRKSLVCQRK----------------GER---------------------
:..*. ::: :* : .*
RNF8_HUMAN ----------------------------------------------------
G3RG85_GORGO ----------------------------------------------------
G1RK27_NOMLE ----------------------------------------------------
RNF8_PONAB ----------------------------------------------------
G7P3D2_MACFA ----------------------------------------------------
F7BPC7_MACMU ----------------------------------------------------
A0A096NHV0_PAPAN ----------------------------------------------------
A0A0D9RDL7_CHLSB ----------------------------------------------------
H0XEE3_OTOGA ----------------------------------------------------
F1RVS2_PIG ----------------------------------------------------
I3L6W2_PIG ----------------------------------------------------
RNF8_BOVIN ----------------------------------------------------
M3YRF5_MUSPF ----------------------------------------------------
G1MA53_AILME ----------------------------------------------------
E2RKD8_CANLF ----------------------------------------------------
J9P6M8_CANLF ----------------------------------------------------
G1PN75_MYOLU ----------------------------------------------------
U3KPJ3_RABIT ----------------------------------------------------
RNF8_MOUSE ----------------------------------------------------
RNF8_RAT ----------------------------------------------------
E1C4A8_CHICK YNGSYCVI--------------------------------------------
G1NE57_MELGA ----------------------------------------------------
A0A0Q3RF81_AMAAE YNESYYII--------------------------------------------
A0A151P3T7_ALLMI YDDSYYVI--------------------------------------------
A0A151P2W8_ALLMI ----------------------------------------------------
K7GJT8_PELSI ----------------------------------------------------
RNF8B_XENLA FWMVNEEEEYEESLFGCGTDELDSSDFESDDD---DSFLIV-----------
RNF8A_XENLA FWMRSEEEEYEETLFGCGTDELDSSDFESDDDEEEDSFLII-----------
RNF8_DANRE --------------SGGNK---------------------------------
I3IRX0_DANRE --------------SDGDTFFQSNSSIFPDSSGSDDSLILEDSSWTEEDDYL
W5LR09_ASTMX --------------DNDSSVYLSTEGYLINPRIPYCVDTSDSSSWSD-----
A0A087YLS4_POEFO -------SMVSINSSLSSVVSVETDSSIHVDS--------EDSFDELEV---
M4ASE8_XIPMA ----------------------------------------------------
G3PJP4_GASAC -------SLVSIDSSLSSAVSLETDTSIHLDSSPDYSGYSDQSLDGFED---
I3JF49_ORENI SNSDSNSSMVSIDSSLSSVLSVDTDSSIHLESSSPYSGYSDDSSDEDED---
H2SP54_TAKRU ----------------------------------------------------
H2M926_ORYLA ----------------------------------------------------
W5NHZ5_LEPOC ----------------------------------------------------