CLUSTAL format seed alignment for MF_03141
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
LIS1_AJECG ----------MARLLTNRQADELHKSIIAYLSANDLPNTAAALR-------AEL-NLTEE
LIS1_AJECH ----------MARLLTNRQADELHKSIIAYLSANDLPNTAAALR-------AEL-NLTEE
LIS12_ASPCL ----------MARLLTNSQAEELHKSIIAYLSANGLPETTAILR-------KEL-GVTEH
LIS11_TALMQ ----------MSRLLTIRQAEELHKSIIAYLSANNLSNAASALR-------GEL-GLSEE
LIS1_TALSN ----------MSRLLTIRQAEELHKSIIAYLSANNLTNAAAALR-------AEL-GLSEE
LIS1_ASPFN ----------MPPLLTNRQAEELHKSMIAYLVASDLPDTAAALR-------REV-NLSED
LIS1_ASPOR ----------MPPLLTNRQAEELHKSMIAYLVASDLPDTAAALR-------REV-NLSED
LIS12_CHAGB ----------MNPVLTSRQADELHKSIVAYLTANNLSTTAATLR-------EEL-SLGED
LIS1_ARTBC ----------MSPILTNRQAEELHKSIIAYLTANNLLDTANTLR-------AEL-NLNED
LIS1_TRIVH ----------MSPILTNRQAEELHKSIIAYLTANNLLDTANTLR-------AEL-NLNED
LIS1_ARTOC ----------MSPILTNRQAEELHKSIIAYLTANNLLNTANTLR-------AEL-NLSEN
LIS1_PYRO7 ----------MTSILTPRQAEELHKAIIAYLSANNLSSSATALR-------TEL-GLAED
LIS12_UNCRE ----------MKIGFWTWKSIKLSIAIPLMCS-----HVSSALR-------AEL-GLDEE
LIS1_GIBZE ----------MSRTLTSRQAEELHKSIIAYLAANNLQDSANAMR-------TEL-GLGED
LIS1_FUSV7 ----------MSRTLTSRQAEELHKSIIAYLAANNFQDSVTAMR-------TEL-NLGEE
LIS11_CHAGB ----------MAQLLTSRQAEELHRALIAYLSSNNLTSTAAALR-------AEI-GLGED
LIS11_PODAN ---------MNTNILTTRQAEELHKAIIAYLTANNLSNTASALR-------TEL-NLGED
LIS11_NEUCR ----------MSQILTSRQADELHRALIAYLTAANLPNTAAALR-------EEL-NLSEE
LIS11_SORMK ----------MSQILTSRQADELHRALIAYLTAANLPNTAAALR-------EEL-NLGED
LIS1_AJEDR ----------MSQLLTPRQAEELHKSIIAYFLSAKLPKSAAALR-------EEI-ADSVQ
LIS1_BLAGS ----------MSQLLTPRQAEELHKSIIAYFLSAKLPKSAAALR-------EEI-ADSVQ
LIS1_PARBP ----------MSQLLTARQAEELHKAMIAYLLSANLPKSAAALR-------EEL-ADSVQ
LIS1_PARBD ----------MSQLLTARQAEELHKAMIAYLLSANLPKSAAALR-------EEL-ADSVQ
LIS1_COCP7 ----------MSQLLTARQAEELHKSMIAYLLSVNLSKSAAALR-------EEL-ADSVH
LIS1_ASPFU ----------MSQLLTARQAEELHKSIIAYLASVNLTESSAALR-------AEL-GDSVS
LIS1_NEOFI ----------MSQLLTARQAEELHKSIIAYLASVNLTESSAALR-------AEL-GDSVS
LIS1_ASPFC ----------MSQLLTARQAEELHKSIIAYLASVNLTESSAALR-------AEL-GDSVS
LIS11_ASPCL ----------MSQLLTTRQAEELHKSIIAYLASVNLSESATTLR-------AEL-GDAVT
LIS11_PENRW ----------MSQLLTSRQAEELHKGIIAYLTSVNLHHSSAALR-------EEL-GDSIR
LIS1_SCLS1 ----------MSQLLTSRQAEELHKSMIAYLNSANLLHSAATLR-------EEL-DIGES
LIS1_PHANO ----------MSAILTDRQAEELHKAIIAYLGVINAPKTAAAFR-------EEV-NFSAA
LIS1_PYRTR ----------MSAILTDRQAEELHKAIIAYLGVINAPKTAEAFR-------EEA-NVSAN
LIS12_NEUCR --MAQASVQIGTPLLTTRQAEELHKSILAYLASKNLATTAATLR-------DEL-DLAEE
LIS12_SORMK ----MAQAQIGTPLLTTRQAEELHKSILAYLSSKNLASTAATLR-------DELPDLAEV
LIS12_PODAN ------MTMASRSFLTDRQAEELHKSIIAYLTSLNLATTANTLR-------AEL-NLPEE
LIS12_PENRW ----------MPSSLTPQQAAELNKSIIAYLSAHGLAETLAAFR-------KES-DFPDN
LIS1_ASPTN ----------MSQILTASQAEELHKSMVAYLSSIKASQSSNTLR-------EEL-GIGDN
LIS12_TALMQ ----------MSQILTTRQAEELHKSMVAYLSSLEASKSTAALR-------EEL-VLPDT
LIS1_EMENI ----------MSQILTAPQAEALHKAMLAYLSVINAPQTAETLR-------EEL-HFDES
LIS1_ASPNC ----------MTKILTSSQAEELHKSIIAYLSSINASRSCEVLR-------EEL-QVDSS
LIS11_UNCRE ----------MSQILTGRQAEELHKSLIAYLSSINASQSVTTLR-------EEL-QIGDN
LIS1_TUBMM -------MSTPVNYLIPRQKDELHKAILAYFSASGLSNTGAALR-------EEL-GVGDE
LIS1_PANTR ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_PIG ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_RAT ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_FELCA ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_MOUSE ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_PONAB ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_BOVIN ------------MVLSQRQRDELNRAIADYLRSNGYEAAYSVFK-------KEA-ELDM-
LIS1_MACFA ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_HUMAN ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDV-
LIS1_CHICK ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDV-
LIS1_XENLA ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_XENTR ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1B_SALSA ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSTFK-------KEA-ELDM-
LIS1_TETNG ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSTFK-------KEA-ELDN-
LIS1B_DANRE ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSTFK-------KEA-ELDV-
LIS1A_SALSA ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSTFK-------KEA-ELDM-
LIS1A_DANRE ------------MVLSQRQRDELNRAIADYLRSNGYEEAYSVFK-------KEA-ELDM-
LIS1_BRAFL ------------MVLSQRQREELNKAIADYLRSNGYESALEAFQ-------KEA-EMP--
LIS1_NEMVE ------------MVLTPRQKEELNKAIADYLHQCGFEDTLNAFK-------QDA-NMP--
LIS1_IXOSC ------------MVLSQRQREELNKAIADYLASNGFMEALESFK-------KET-DMP--
LIS1_DROGR ----------MKMVLSQRQREELNQAIADYLGTNGYADSLEAFR-------KEA-DLS--
LIS1_DROWI ------------MVLSQRQREELNQAIADYLGTNGYADSLEAFR-------KEA-DLS--
LIS1_DROVI ----------MKMVLSQRQREELNQAIADYLGSNGYADSLEAFR-------KEA-DLS--
LIS1_DROAN ----------MKMVLSQRQREELNQAIADYLGSNGYADSLEAFR-------KEA-DLS--
LIS1_DROPE ----------MKMVLSQRQREELNQAIADYLGSNGYGDSLETFR-------KEA-DVS--
LIS1_DROPS ----------MKMVLSQRQREELNQAIADYLGSNGYGDSLETFR-------KEA-DVS--
LIS1_DROMO ----------MKMVLSQRQREELNQAIADYLGSNGYADSLETFR-------KEA-DLS--
LIS1_DROER ----------MKMVLSQRQREELNQAIADYLGSNGYADSLETFR-------KEA-DLS--
LIS1_DROYA ----------MKMVLSQRQREELNQAIADYLGSNGYADSLETFR-------KEA-DLS--
LIS1_DROME ----------MKMVLSQRQREELNQAIADYLGSNGYADSLETFR-------KEA-DLS--
LIS1_DROSE ----------MKMVLSQRQREELNQAIADYLGSNGYADSLETFR-------KEA-DLS--
LIS1_DROSI ----------MKMVLSQRQREELNQAIADYLGSNGYADSLETFR-------KEA-DLS--
LIS1_GLOMM ----------MKMVLSQRQREELNQAIADYLGSNGYSSALEAFR-------KEA-DIS--
LIS1_AEDAE ------------MYVRRLRRERSNQAIADYLGSNGYTDALEAFR-------KEA-DMP--
LIS1_TRIAD ------------MVLSPKQEEELRFAVADYLQSCGYTNALEAFK-------KDA-SIP--
LIS1_CAEBR ------------MSLSERQREEINRAVAEYLQNNGYSEAFNMLL-------KEA-SLS--
LIS1_CAEEL ------------MSLSERQKEEINRAIAEYMQNNGYSESFSVFL-------KES-SLS--
LIS1_SCHMA ------------MVLAQRQKEELNRAIADYLFANGYVKALNAFR-------EES-QLA--
LIS1_DICDI ------------MVLTSKQKEELNGSILDYFESSQYKSSFEEFK-------KET-GTE--
LIS1_POLPP ------------MVLTNKQKEELNGAILDYFDSSGYKLTSTEFT-------KET-NIE--
LIS1_MONBE ------------MVLTARQQEELQLAVHAYLVEAGHAEAAAAMA-------KSA-NLG--
LIS11_PARTE ------------MVLTARQRDELNQAIHQYLLIS-YQQSAQLFK-------TEA-AVK--
LIS12_PARTE ------------MVLTARQRDELNQAIHQYLLIS-YQQSAQVFK-------TEA-VVK--
LIS1_PHATC ------------MVLTDRQRADLHAGIYEYLQSR-GDAYQKVVE-------ALA-QADPE
LIS11_POSPM -----------MSILSERQKDDLNKSIAEYLYAQDLTEIADSLC-------ARL-SLDYK
LIS12_POSPM -----------MSILSERQKDDLNKSIAEYLYAQDLTEIADSLC-------ARL-SLDYK
LIS1_COPC7 -----------MSLLSDRQKDDLHKAMLDYLYANNHTAAFNALK-------ESA-GITYT
LIS1_CRYNJ -----------MAALSDRQKDELHRAMLAYLHAAGMHNAYAALQ-------HDA-ALADV
LIS1_USTMA MSGFNGTSTSSNSILSERQKDELHKSILDYFKTNNLHESFATLM-------REA-NQEGF
LIS1_YARLI ----------MESLLTDKQRSDLETSIFGYVSRLTNDEALLSQL-------AAVLSQPSG
LIS1_CANAW --------MEKLQILTERQQTELNHAIIQYLQPLCQQDNH-----------VLLDQLSKL
LIS1_CANAL --------MEKLQILTERQQTELNHAIIQYLQPLCQQDNH-----------VLLDQLSKL
LIS1_CANDC --------MEKLSILTERQQTELNYAIIQYLQPLCQQDNH-----------ALLDQLSKI
LIS1_CANTT -------MMERSQILTERQQSELNKAIIQYLQPICSQENN-----------EVLDKLTSM
LIS1_DEBHA --------MLQPQILTARQQQELNKAIIQYIKPIAEEAN-------------DGDLIQKL
LIS1_PICST --------MNRSQILTDRQQQELNKAILQYLEPMLTESSS------------DQEVYRSL
LIS1_PICGU -----------MSILSPRQQQELNRAIVQYIGKIISDNSENLEHGEKNGVLQHQDLVDKV
LIS1_EREGS --------MSQHHILPQHQRADLNRSICDYVQRCGAEE-------------SLVVGLRQL
LIS1_KLULA -------------MLTYKQRQSLNHAICDYVRQNEGSD-------------ELLVQLESV
LIS1_LACTC -----------MSLLPPEQRQLLHRCILNYIRSQVPGDGAEGETGGQTEERHVMNSLAKW
LIS1_YEAST -----MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRH----------EHAQDYESV
LIS1_YEAS7 -----MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRH----------EHAQDYESV
LIS1_YEAS8 -----MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRH----------EHAQDYESV
LIS1_YEAS1 -----MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRH----------EHAQDYESV
LIS1_YEAS2 -----MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRH----------EHAQDYESV
LIS1_CANGA -----------MSSLTDSQVNDLHCSIYRYVQWVSQNNGSS----------DLLNKLQSV
LIS1_ZYGRC ----------MDLPLSDEQIRELDESTLDYLLWRNKGIDIT----------QLANSLQVD
LIS1_KOMPG ----------MSDILTKKQDIELRRAVIQYLRYFVPEFAQDTAV-------NTISRLLLD
. :
LIS1_AJECG D---------FDATAVKK-----------------YETLLEKKWTSIVRLQKKI------
LIS1_AJECH D---------FDATAVKK-----------------YETLLEKKWTSIVRLQKKI------
LIS12_ASPCL D---------FNATAVKK-----------------YETLLEKNGPLLFAYRES-------
LIS11_TALMQ V---------FDTGTMVK-----------------YETLLEKKWTSIVRLQKKI------
LIS1_TALSN V---------FDTGTMVK-----------------YETLLEKKWTSIVRLQKKI------
LIS1_ASPFN V---------FDPTTAKR-----------------YEGMLEKKWTSIARLQKKI------
LIS1_ASPOR V---------FDPTTAKR-----------------YEGMLEKKWTSIARLQKKI------
LIS12_CHAGB V---------FDAEKTAK-----------------YQSLLEKKWTSVVRLQKKV------
LIS1_ARTBC A---------FDPATAKK-----------------YETLLEKKWTSVVRLQKKI------
LIS1_TRIVH A---------FDPATAKK-----------------YETLLEKKWTSVVRLQKKI------
LIS1_ARTOC A---------FDTATAKK-----------------YETLLEKKWTSVVRLQKKI------
LIS1_PYRO7 V---------FDAATAKK-----------------YEGLIEKKWTSVVRLQKKI------
LIS12_UNCRE A---------FGTAAAKK-----------------YETLLEKKWTSIVRLQKKI------
LIS1_GIBZE A---------FDTATAKK-----------------YETLLEKKWTSVVRLQKKI------
LIS1_FUSV7 I---------FDPATAKK-----------------YETLLEKKWTSVVRLQKK-------
LIS11_CHAGB V---------FDATTAKK-----------------YEGLLEKKWTSVVRLQKK-------
LIS11_PODAN V---------FDPATAKK-----------------YEGLLEKKWTSVVRLQKK-------
LIS11_NEUCR V---------FDPATAKK-----------------YEGLLEKKWTSVVRLQKK-------
LIS11_SORMK V---------FDPATAKK-----------------YEGLLEKKWTSVVRLQKKSLTPLVT
LIS1_AJEDR ----------LDDSTAKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS1_BLAGS ----------LDDSTAKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS1_PARBP ----------LDDSTAKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS1_PARBD ----------LDDSTAKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS1_COCP7 ----------LDDATAKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS1_ASPFU ----------IDDATLKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS1_NEOFI ----------IDDATLKK-----------------YEGLLEKKWTSVVRLQKK-------
LIS1_ASPFC ----------IDDATLKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS11_ASPCL ----------IDDATIKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS11_PENRW ----------VDDTTLKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS1_SCLS1 ----------FDSATSKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS1_PHANO ----------FDDATRKK-----------------YEGLLEKKWTSVVRLQKKV------
LIS1_PYRTR ----------FDDATRKK-----------------YEGLLEKKWTSVVRLQKKV------
LIS12_NEUCR S---------FDAEKAKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS12_SORMK T---------FDTEKAKK-----------------YEGLLEKKWTSVVRLQKKI------
LIS12_PODAN T---------FDLAKAKQ-----------------YEGLLEKKWTSVIRLQKKV------
LIS12_PENRW M---------FDATAAKQ-----------------YENLLERKWTSNSTLMKKL------
LIS1_ASPTN F----------DEATCKK-----------------YEGLLEKKWTGIARLQR--------
LIS12_TALMQ F----------DDATCKK-----------------YAGLLEKKFLTCSLKANPSKDNGLS
LIS1_EMENI Y----------NEATCKK-----------------FEGVLEKKWTGIARLQR--------
LIS1_ASPNC F----------DDALCRK-----------------YEGLLEKKWTGIARLQK--------
LIS11_UNCRE F----------TDAACKK-----------------YEGFLEKKWISVVRLQK--------
LIS1_TUBMM F---------LDQNTMKK-----------------YEGVLEKKWTGVLRLQK--------
LIS1_PANTR ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_PIG ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_RAT ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_FELCA ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_MOUSE ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_PONAB ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_BOVIN ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_MACFA ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_HUMAN ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_CHICK ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_XENLA ----------NEELDIK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_XENTR ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1B_SALSA ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_TETNG ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1B_DANRE ----------NDELDKK------------------FAGLLEKKWTSVIRLQKKV------
LIS1A_SALSA ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1A_DANRE ----------NEELDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_BRAFL -----------GEIEKK------------------YTGLLEKKWTSVIRLQKKV------
LIS1_NEMVE -----------GELDKK------------------YTGLLEKKWTSVIRLQKKV------
LIS1_IXOSC -----------GDIDKK------------------YAGLLEKKWTSVIRLQKKV------
LIS1_DROGR -----------TEAEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROWI -----------TEAEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROVI -----------TEAEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROAN -----------TEAEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROPE -----------TESEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROPS -----------TESEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROMO -----------TESEKK------------------YGGLLEKKWTSVIRLQKKV------
LIS1_DROER -----------TEVEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROYA -----------TEVEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROME -----------TEVEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROSE -----------TEVEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_DROSI -----------TEVEKK------------------FGGLLEKKWTSVIRLQKKV------
LIS1_GLOMM -----------GEAERK------------------IVGLLEKKWTSVIRLQKKV------
LIS1_AEDAE -----------NEIERK------------------YGGLLEKKWTSVIRLQKKV------
LIS1_TRIAD -----------KEIDNKK-----------------YSGLLEKKWTSVVRLQKKV------
LIS1_CAEBR ------------ENDIKP-----------------LGGILEKKWTTVLRLQRKV------
LIS1_CAEEL ------------ENDIKP-----------------LGGILEKKWTTVLRLQRKV------
LIS1_SCHMA -----------GENDRK------------------YDGLLEKKWTSVIRLQKKV------
LIS1_DICDI -------------LDVK------------------KKGLLEKKWTSVIRLQKKV------
LIS1_POLPP -------------LDPK------------------LKGLLEKKWTSVIRLQKKV------
LIS1_MONBE -----------DDAGDAK-----------------YTGLLEKKWTTITRLQKRN------
LIS11_PARTE --------------DGQI-----------------EADLLEKKWNSIVRLSKRV------
LIS12_PARTE --------------DGQI-----------------EADLLEKKWNSIVRLSKRV------
LIS1_PHATC CTIPHTTTTSNGSSAGLT-----------------KTPLLEKKWTAIPRLQKKV------
LIS11_POSPM -----------SEPNSK------------------YAGLLEKKWVSVIRLQKKL------
LIS12_POSPM -----------SEPNSK------------------YAGLLEKKWVSVIRLQKKL------
LIS1_COPC7 -----------PDPTAR------------------YTGLLEKKWTSVIRLQKKI------
LIS1_CRYNJ ------------DPRDR------------------AVGLLEKKWTSVIRLQKKV------
LIS1_USTMA V----------PDPRAK------------------YAGLLEKKWTSVIRLQKKI------
LIS1_YARLI SEP-------VPADTLKA-----------------NALLLEKKWLSVIRLQRKV------
LIS1_CANAW LNIDQSTQESNNVEKVDN--------------------YLEKRWSTVLRLQKKI------
LIS1_CANAL LNIDQSTQESNNVEKVDN--------------------YLEKRWSTVLRLQKKI------
LIS1_CANDC LNIDQWTQESNNVEKVDN--------------------YLEKRWSTVLRLQKKI------
LIS1_CANTT LKIESTELDGS--DIVDN--------------------YLEKKWSTVLRLQKKI------
LIS1_DEBHA SESLDVPLGSIDDSVIPN--------------------YLEKKWSTVLRLQHKI------
LIS1_PICST QQILVPPSSSSSEAIVDN--------------------YLEKKWSTVLRLQRKI------
LIS1_PICGU ANLLDVPTSS--EDLTTN--------------------YLEKKWSTVLRLQRKI------
LIS1_EREGS FGL----SAEECDATRN----------------GRDPDLLLKKWNSIIRLHRKI------
LIS1_KLULA LLP----NGSDVIPQ--------------------DPNLLERKWNSIVRLQSKI------
LIS1_LACTC LRV----DPDGLDGEK-----------------AADGSLLPRKWSSIVRLQRRI------
LIS1_YEAST RHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKI------
LIS1_YEAS7 RHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKI------
LIS1_YEAS8 RHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKI------
LIS1_YEAS1 RHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKI------
LIS1_YEAS2 RHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKI------
LIS1_CANGA ------LDIDELQLSLD----------------DGDQMLLPKKWGSIIRLQRAI------
LIS1_ZYGRC --------APTLQEDTNR------------------LPLLARKWTAIARLQRRI------
LIS1_KOMPG ADL-----NKFDNEIQRM----------------IPKQYLEKKWTAVLRLHRKV------
: :.
LIS1_AJECG ----MDLEARNAALQSELDNLTP-------------ASLLKPRRDPTSWLPTHPP-RYSL
LIS1_AJECH ----MDLEARNAALQSELDNLTP-------------ASLLKPRRDPTSWLPTHPP-RYSL
LIS12_ASPCL -------------------------------------------RDSKAWLPQRP--RYSL
LIS11_TALMQ ----MDLEARCGALQTELNNATP-------------TSLSKRNQDPASWLPKVPA-RYSL
LIS1_TALSN ----MDLEARTVALQTELNNATP-------------TSLSKRNQDPASWLPKVPA-RYSL
LIS1_ASPFN ----MDLESRNATLQSELDNSTP-------------ASRLKRNQDPASWLPSTV--RYSL
LIS1_ASPOR ----MDLESRNATLQSELDNSTP-------------ASRLKRNQDPASWLPSTV--RYSL
LIS12_CHAGB ----MDLESRSVALQSELEHSTP-------------ASLSKR-KDPTSWLPRSPP-RHSL
LIS1_ARTBC ----MDLESRMSAMQAELDNATP-------------TSLSKRNKDPASWIPTAPA-RHAL
LIS1_TRIVH ----MDLESRMSAMQAELDNATP-------------TSLSKRNKDPASWIPTAPA-RHAL
LIS1_ARTOC ----MDLESRMSALQTELDNATP-------------ISLAKRNKDPASWIPTAPA-RHAL
LIS1_PYRO7 ----MDLESRNNALQSELDNATP-------------LSLAKRNTDPTAWLPAPRP-RYSL
LIS12_UNCRE ----MDLESRNAALQTELANLTP-------------TALSKRHQDPASWLPRS-V-RHSL
LIS1_GIBZE ----MDLEAQTQTLQTELNSATP-------------TS--NRRGDPSSWLPAGPP-RHVL
LIS1_FUSV7 ---------------TELDSATP-------------TSLSNRKQDPASWLPAGPP-RHVL
LIS11_CHAGB ---VRHT--------SQLSNATP-------------TS--RQNKDPVNWLPKSPA-RHTL
LIS11_PODAN ---IMDLESRNSTLQSELANSTP-------------TS--RQNKDPVAWLPKSPA-RHTL
LIS11_NEUCR ---IMDLESRNHILQSELDNATP-------------TS--RQNKDPVAWLPRAPP-RHTL
LIS11_SORMK --QIMDLESRNHILQSELDNATP-------------TS--RQNKDPVAWLPRAPP-RHTL
LIS1_AJEDR ----MDLEARNSALQSELDSATP-------------TSLSRRNQDPVSWLPRAPA-RHRL
LIS1_BLAGS ----MDLEARNSALQSELDSATP-------------TSLSRRNQDPVSWLPRAPA-RHRL
LIS1_PARBP ----MDLESRNNALQSELDSATP-------------TSLARRNQDPVSWLPHAPA-RHIL
LIS1_PARBD ----MDLESRNNALQSELDSATP-------------TSLARRNQDPVSWLPHAPA-RHIL
LIS1_COCP7 ----MDLESRNAALQQELDSATP-------------TSLSRRNQDPASWLPRAPA-RHSL
LIS1_ASPFU ----MDLESRCAALQSELDSATP-------------TSLLRKNQDPTSWLPRSPA-RHIL
LIS1_NEOFI ------------------------------------------NQDPTSWLPRSPA-RHIL
LIS1_ASPFC ----MDLESRCAALQSELDSATP-------------TSLLRKNQDPTSWLPRSPA-RHIL
LIS11_ASPCL ----MDLESRCAALQSELDSATP-------------TSLLRKNQDPTAWLPRAPP-RHTL
LIS11_PENRW ----MDLEARCASLQSELDTATP-------------TSLNRKNQDPVSWLPRAPA-RHDL
LIS1_SCLS1 ----MDLESRNAALQSEIDNATP-------------TSLSNRNTDPTAWLPKSPA-RHNL
LIS1_PHANO ----LELEQRNQSLQSELDSTTP-------------TSLLRRNQDPSSWLPRAPA-RHTL
LIS1_PYRTR ----MELEQRNQTLQSELDSTTP-------------TSLLRRNQDPASWLPRAPA-RHTL
LIS12_NEUCR ----LDLESRNHLLQSEIDNATP-------------SSLSRRTQDPTNWLPKAPP-RYVL
LIS12_SORMK ----LDLESRNTLLQSEIDNATP-------------SSLSRRTQDPTNWLPKAPP-RYVL
LIS12_PODAN ----LDLQAENAHLKNEIENAGP-------------LALSRKNQDPANWLPKGPP-RYTL
LIS12_PENRW ----LALESHNKALRNELNSTRP-------------SFL-NRNADVNDWLPQHP--IRSL
LIS1_ASPTN --KILDLESKITSLQAELDSVPS-------------MARSKQHQDPDNWLPAQSS-AHTF
LIS12_TALMQ ALQILDLESKVAGLQAELSSLTL-------------TSRSKGGQDPDNWLPGPAS-TRTF
LIS1_EMENI --RINDLEAEVRSLQAELEASPS-------------AARAK-NQDPTNWLPKPSS-THTL
LIS1_ASPNC --KILDLESKLAGLQTELDTISP-------------TARST-GKDPINWLP-TSS-RHTF
LIS11_UNCRE --RILDLESKIASLQAELDSAPT-------------I-TSRANRDPKSWLPGTSP-THTL
LIS1_TUBMM --KIMELESRLSSLQSELDSATP-------------TSLTRRNVDPSSWLPRAPA-KHVL
LIS1_PANTR ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_PIG ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_RAT ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_FELCA ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_MOUSE ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_PONAB ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_BOVIN ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_MACFA ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_HUMAN ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_CHICK ----MELESKLNEAKEEFTS----------------GGPLGQKRDPKEWIPRPPE-KYAL
LIS1_XENLA ----MELESKLNEAKEEFTS----------------GGPIGQKRDPKEWIPRPPE-KYAL
LIS1_XENTR ----MELESKLNEAKEEFTS----------------GGPIGQKRDPKEWIPRPPE-KYAL
LIS1B_SALSA ----MELESKLNEAKEEITL----------------GGPVAQKRDPKEWIPRPPE-RYAL
LIS1_TETNG ----MELESKLNEAKEEITL----------------GGPVSQKRDPKEWIPRPPE-RYAL
LIS1B_DANRE ----MELESKLNEAKEEITL----------------GGPVGQKRDPKEWIPRPPE-KYAL
LIS1A_SALSA ----MELESKLNEAKEEITL----------------GGPIAQKRDPKEWIPRPPE-KYAL
LIS1A_DANRE ----MELESKLNEAKEEINI----------------GGPIGQKRDPKEWIPRPPE-KYAL
LIS1_BRAFL ----MDLEAKLAEAEKEFQS----------------GGPNKKERSPSEWIPRPPA-RYSL
LIS1_NEMVE ----MDLETRLSEAEKEVHH----------------GGGPKKTRSPEDWIPRPPE-RYTL
LIS1_IXOSC ----MDLEGRLAEAEKEYIS----------------GTPSREKRSPTEWIPRPPE-RSAL
LIS1_DROGR ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KYSL
LIS1_DROWI ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KYSL
LIS1_DROVI ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KYSL
LIS1_DROAN ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KYSM
LIS1_DROPE ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KYSL
LIS1_DROPS ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KYSL
LIS1_DROMO ----MDLEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KYSL
LIS1_DROER ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KFSL
LIS1_DROYA ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KFSL
LIS1_DROME ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KFSL
LIS1_DROSE ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KFSL
LIS1_DROSI ----MELEAKLTEAEKEVIE----------------GAPTKNKRTPGEWIPRPPE-KFSL
LIS1_GLOMM ----MELEAKLSEAEKEVIE----------------GAPSRAKRSPGEWIPRPPE-KFSL
LIS1_AEDAE ----MELEAKLSEAEKEAIE----------------GAPTKAKRTPTDWIPRPPE-KFAL
LIS1_TRIAD ----MDLELRLNNTTREMNS----------------GVPTRNSRSSNDWIPRPPE-KHSL
LIS1_CAEBR ----NDLEAKLLESQQEINH----------------GAPTRDKRQAADWIPRPPE-TQKL
LIS1_CAEEL ----NDLESKLQESQREINH----------------GAPTRDKRQAADWIPRPPE-TQKL
LIS1_SCHMA ----MDLEAKLNEAEKEFQSMQNAIGFGVAGAAPGSGLSDRSDRRDVDAIPRPPA-KFTL
LIS1_DICDI ----LDLEAKVAQLEEELNSGGG--------------RGGGRGRGKEDALPRPPE-KHIL
LIS1_POLPP ----MDLEAKVSQLEEELNNGG---------------RGPAR-RGKEDALPRQPE-KHVL
LIS1_MONBE ----MELQAEVEELRSSARAP-----------------RSRTTTKMEEWVPRPPA-TVAV
LIS11_PARTE ----ITLEQQVEQLNEQLAQAQAGK------IQFNKSDDEQRLTPIEKF---------KL
LIS12_PARTE ----ITLEQQVEQLNEQLAQAQAGK------IQFNKSDDEQRLTPFEKF---------KL
LIS1_PHATC ----LELERQASHHAKIHAHRSAAG------SGGGALEANDGAGGARRLLPRLPC-QHTL
LIS11_POSPM ----IESENRYTALQEDIAAGPAR-----------------RRDAQVDWLPTAPA-RYTL
LIS12_POSPM ----IESENRYTALQEDIAAGPAR-----------------RRDAQVDWLPTAPA-RYTL
LIS1_COPC7 ----MELENRNAALQEELSMSPAR-----------------RAASQADWLPRAPA-AHVL
LIS1_CRYNJ ----IDLENRNAALLAELAAAA-------------------RPAAPGPFLPRPPP-RHTL
LIS1_USTMA ----MEMESRISQLQEELSAAPSAK----------------RSASLNDWLPAASSARHTM
LIS1_YARLI ----MDLETRLEAAEREASSTHK--------------ANGLGAGDPKTWLPKTSR---FS
LIS1_CANAW ----IDLENEISNLNNIIN----------STN--SDNNGIILSKDKINWIPKGAVKQ-SY
LIS1_CANAL ----IDLENEISNLNNIIN----------STN--SDNNGIILSKDKINWIPKGAVKQ-SY
LIS1_CANDC ----IDLENEISNLNNIIN----------SSN--SDNNGIVLSKDKINWIPKGTAKQ-SY
LIS1_CANTT ----IDLENEIHNLTNIIN----------TTN--SETNGVVLSKDKINWIPKGASKQ-TY
LIS1_DEBHA ----IDLEGEVSNLRTVID----------SQQIVPSASASVIGKDKINWLPSSSIKAFKT
LIS1_PICST ----IDLENEVGTLRSIVD----------GQQSVSNGAASVISKDRINWLPNRASKSFPT
LIS1_PICGU ----MDLTDEVSNLKTIIE----------AKH---ANGGSEISKDKINWLPTSVFKTFPT
LIS1_EREGS ----LDLEQKCQQLTE-----------ELEAVPTEAYGKAGRGVSHVLWTPRS-NPTFQL
LIS1_KLULA ----MELEKNCEELQK-----------SIDEQQSSTNQISNASSD---WCPRD-TPSFQI
LIS1_LACTC ----IELEKEIQELTD-----------ENENLR-ENGPSSPANGALKSWLPRE-RPSFSI
LIS1_YEAST ----IELEQNTETLVSQIKDLNTQV--SELAQFKPTTSNGTSAHNVLKWIPRN-LPSCLI
LIS1_YEAS7 ----IELEQNTETLVSQIKDLNTQV--SELAQFKPTTSNGTSAHNVLKWIPRN-LPSCLI
LIS1_YEAS8 ----IELEQNTETLVSQIKDLNTQV--SELAQFKPTTSNGTSAHNVLKWIPRN-LPSCLI
LIS1_YEAS1 ----IELEQNTETLVSQIKDLNTQV--SELAQFKPTTSNGASAHNVLKWIPRN-LPSCLI
LIS1_YEAS2 ----IELEQNTETLVSQIKDLNTQV--SELAQFKPTTSNGTSAHNVLKWIPRN-LPSCLI
LIS1_CANGA ----TKLEQKCDALQQELDDKTKQL--ETIVPKDTQIATTTDVN----WLPPD-HIYASI
LIS1_ZYGRC ----MSLEQNIRDLRE-----------ASIEMNAPAFSPESSESARIAWIAPA-QPRASI
LIS1_KOMPG ----EELERTIGYQSNKVEIELQSQ---------PHSDITSNSLDRINWVPGIEPFQKLN
LIS1_AJECG ESHRDTINCIAFHPKFSSLASGSDDFTIKIWDWEL---GELEMTLKGHTRAVLDVDYGSP
LIS1_AJECH ESHRDTINCIAFHPKFSSLASGSDDFTIKIWDWEL---GELEMTLKGHTRAVLDVDYGSP
LIS12_ASPCL HSHRDTINCIAFHPKYSSIASGSDDCTIKIWDWEL---GELEVTLKGHTRAVRDLDYGSP
LIS11_TALMQ ESHRNTINCLAFHPKFSSIASGSDDCMIKIWDWEL---GELETTLKGHTRAVLDVDYGNT
LIS1_TALSN ESHRSTVNCVAFHPKFSSIASGSDDSMIKIWDWEL---GELEATLKGHTRSVLGVDYGTA
LIS1_ASPFN ESHRDKVNCVAFHPTFSSIASGSDDCTIKIWDWEL---GELERTLKGHTRAVRDVDYGGP
LIS1_ASPOR ESHRDKVNCVAFHPTFSSIASGSDDCTIKIWDWEL---GELERTLKGHTRAVRDVDYGGP
LIS12_CHAGB ESHQAIVNCLAFHPVFSSLASGSDDSTVKIWDWEL---GELERTLKGHTRAVLDIDFGGP
LIS1_ARTBC ESHRDTINSVAFHPIFSSVASASDDCTIKIWDWEL---GELERTIKGHTRAVVDVDFGGP
LIS1_TRIVH ESHRDTINSVAFHPIFSSVASASDDCTIKIWDWEL---GELERTIKGHTRAVVDVDFGGP
LIS1_ARTOC ESHRDTINSVAFHPIFSSIASGSDDCTIKIWDWEL---GELERTIKGHTRAVVDVDFGGP
LIS1_PYRO7 ESHQNTINCIAFHPVYSSIASGSDDCTIKIWDWEL---GELERTIKSHTRPVLDVDFGGP
LIS12_UNCRE ESHRDTINSIAFHPIYSSLASCSDDCTIKIWDWEL---GELERTVKGHTRAVLDVDYGGP
LIS1_GIBZE QSHRTPINCVAFHPIFSSIASGDEDATIKIWDWEF---GELERTVKGHTKAVLDLDYGGP
LIS1_FUSV7 QSHRTPINCVAFHPIYSSIASGDEDAIIKIWDWEF---GELERTVKGHTKAVLDLDYGGP
LIS11_CHAGB QSHRQPITCVAFHPVFSSLASGSEDQTIKIWDWEL---GELERTIKGHTKTVLDVDFGGP
LIS11_PODAN QSHRNPITCVAFHPVFSSLASGSEDQTIKIWDWEL---GELERTIKGHTKAVLDVDFGGP
LIS11_NEUCR QSHRDPITCVAFHPVFSSLASGSEDQTIKIWDWEL---GELERTIKGHTKAVLDVDYGGP
LIS11_SORMK QSHRDPITCVAFHPVFSSLASGSEDQTIKIWDWEL---GELERTIKGHTKAVLDVDYGGP
LIS1_AJEDR ESHRNPVTSVAFHPVFSSLASGSEDTTIKIWDWEL---GELERTIKGHTRAVVDVDYGGP
LIS1_BLAGS ESHRNPVTSVAFHPVFSSLASGSEDTTIKIWDWEL---GELERTIKGHTRAVVDVDYGGP
LIS1_PARBP QSHREPVTCVGFHPVFSSLASGSDDTTIKIWDWEL---GELERTIKGHTKAVLDVDYGGP
LIS1_PARBD QSHREPVTCVGFHPVFSSLASGSDDTTIKIWDWEL---GELERTIKGHTKAVLDVDYGGP
LIS1_COCP7 QSHRGPVTCVAFHPIFSSLASGSEDTTIKIWDWEL---GELERTIKGHTRAVLDVDYGGP
LIS1_ASPFU EGHRNPVTCVAFHPVFSSLASGSDDTTIKIWDWEL---GELERTVKGHTKAVLDVDYGGP
LIS1_NEOFI EGHREPVTCVAFHPVFSSLASGSDDTTIKIWDWEL---GELERTVKGHTKAVLDVDYGGP
LIS1_ASPFC EGHRNPVTCVAFHPVFSSLASGSDDTTIKIWDWEL---GELERTVKGHTKAVLDVDYGGP
LIS11_ASPCL ESHRSPVTCVAFHPVFSSLASGSDDTTIKIWDWEL---GELERTVKGHTKAVLDVDYGGP
LIS11_PENRW ESHRSPVSCLAFHPIFSSLASGSDDTTIKIWDWEL---GELERTIKGHTRAVLDVDYGGP
LIS1_SCLS1 QSHREAITCVAFHPVFSSLASGSEDCTIKIWDWEL---GELELTVKGHTRAVLDVDFGGP
LIS1_PHANO QSHRSPITCVAFHPVFSSLASGSEDTTIKIWDWEL---GELERTVKGHTKGVLDVDFGGP
LIS1_PYRTR QSHRSPITCVAFHPVFSSLASGSEDTTIKIWDWEL---GELERTVKGHTKGVLDVDFGGP
LIS12_NEUCR ESHRLPVTCVAFHPVFTSLASGSEDYTIKIWDWEL---GELERTIKGHTKAVLDVDFGGP
LIS12_SORMK ESHRLPVTCVAFHPVFTSLASGSEDYTIKIWDWEL---GELERTIKGHTKAVLDVDFGGP
LIS12_PODAN EGHRLPITSVAFHPVFSSLASASEDNTIKIWDWEL---GELERTLKGHTKAVLDVDFGGP
LIS12_PENRW ESHRDSINCIAFHPKYSLIASGSGDLTIRIWDWED---STLERTLKGHTMAVCDVDYGDT
LIS1_ASPTN ESHRDAITSIAFHPVFTSLASGSEDCTIKIWDWEL---GELERTLKGHMRGVSGLDFGGQ
LIS12_TALMQ ESHRDAITCIAFHPIFTSLASSSEDCTIKIWDWEL---GELERTLKGHIRAVTGLDFGGQ
LIS1_EMENI TSHRDAVTCVAFHPVFTSLASGSEDCTIKIWDWEL---GEIERTLKGHIRGVSGLDYGGQ
LIS1_ASPNC ESHRDAVTCVAFHPVFTSLASGSEDCTIKIWDWEL---GELERTLKGHMRPVSDLDFGGQ
LIS11_UNCRE GSHRGAITCVAFHPVFSSLASGSEDYSIKIWDWEL---GELERTLKGHTRTVTGLDFGGQ
LIS1_TUBMM TSHRNSINSVAFHPIFSVLASGSDDTTIKIWDWEL---GELERTVKGHTKAVLDLDFGGP
LIS1_PANTR SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1_PIG SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1_RAT SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1_FELCA SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1_MOUSE SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1_PONAB SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSIQDIPFDHS
LIS1_BOVIN SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVEDISFDHS
LIS1_MACFA SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1_HUMAN SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1_CHICK SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHT
LIS1_XENLA SGHRSPVTRVIFHPVFSVMVTASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1_XENTR SGHRSPVTRVIFHPVFSVMVTASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHS
LIS1B_SALSA SGHRSPVTRVIFHPVFSVMVTSSEDATIKVWDYEA---GDFERTLKGHTDSVQDISFDQT
LIS1_TETNG SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDLT
LIS1B_DANRE SGHRSPVTRVIFHPVFSLMVSASEDATIKVWDYEA---GDFERTLKGHTDSVQDISFDQT
LIS1A_SALSA SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET---GDFERTLKGHTDSVQDISFDHT
LIS1A_DANRE SGHRSPVTRVIFHPVFSVIVSASEDATIKVWDHET---GDFERTLKGHTDSVQDISFDHT
LIS1_BRAFL SGHRSPITRVLFHPVYSVMVSASEDATIKIWDYET---GDFERTLKGHTDAVQDVSFDQQ
LIS1_NEMVE TGHRSPITKVLFHPVYSVMVTSSEDATVKVWDYET---GDFERTLKGHTDAVQDLAFDHT
LIS1_IXOSC LGHRAPITRVLFHPVYSVVVSASEDASIKVWDYET---GDFERTIKGHTDSVQDIAFDHT
LIS1_DROGR TGHRASITRVIFHPIFGLMVSASEDATIKIWDFET---GEYERTLKGHTDSVQDVAFDAQ
LIS1_DROWI TGHRASITRVIFHPIFGLMVSASEDATIKIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_DROVI TGHRASITRVIFHPIFGLMVSASEDATIKIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_DROAN SGHRASITRVIFHPIFGLVVSASEDATIKIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_DROPE TGHRASITRVIFHPIFGLMVSASEDATIKIWDFET---GEYERSLKGHTDSVQDVAFDSQ
LIS1_DROPS TGHRASITRVIFHPIFGLMVSASEDATIKIWDFET---GEYERSLKGHTDSVQDVAFDSQ
LIS1_DROMO TGHRASITRVIFHPIFGLMVSASEDATIKIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_DROER TGHRASITRVIFHPIFGLMVSASEDATIRIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_DROYA TGHRASITRVIFHPIFGLMVSASEDATIRIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_DROME TGHRASITRVIFHPIFALMVSASEDATIRIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_DROSE TGHRASITRVIFHPIFALMVSASEDATIRIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_DROSI TGHRASITRVIFHPIFALMVSASEDATIRIWDFET---GEYERSLKGHTDSVQDVAFDAQ
LIS1_GLOMM SGHRASITRVIFHPTYSLMLSASEDAVIKIWDFET---GEYERSLKGHTSSVQDIAFDSQ
LIS1_AEDAE AGHRATVTRVVFHPVFSMMASASEDATIKIWDFET---GEYERTLKGHTDSVQDLAFDSH
LIS1_TRIAD SGHRSPITCVVFHPVYNVMVSSSEDASMKIWDYES---GDFERTLRGHTDSVQDLAFDSS
LIS1_CAEBR IGHRLPVTRVIFHPLWTIMASCSEDATIKVWDYET---GQLEKTLKGHTDAVNDIAIDAA
LIS1_CAEEL TGHRLPITRVIFHPLWTIMASCSEDATIKVWDYET---GQLERTLKGHTDAVNDIAIDAA
LIS1_SCHMA TGHRSPITRVLFHPHYNVFVSASEDASIKVWDYET---GEFEHTLKGHTDSVQDVAFDPS
LIS1_DICDI TGHRNCINSVKFHPSFSLMVSASEDATIKVWDFES---GEFERTLKGHTNAVQDIDFDKT
LIS1_POLPP TGHRNCINAVRFHPLFSVIVSASEDATMRIWDFDS---GDFERTLKGHTNAVQDIDFDKS
LIS1_MONBE DGHRLPITAVAIHPSFAVMASASEDASIKLWDMES---GNFERSLKGHTNAVNDIAYDRE
LIS11_PARTE EGHRAGVNCVAFHPQYQILGSASDDGSIKLWDYES---GHFEKTLKGHTSNVNCLAFDPT
LIS12_PARTE EGHRAGVNCVAFHPQYQILGSASDDGSIKLWDYES---GHFEKTLKGHTSNVNCLAFDPT
LIS1_PHATC QGHSSVVTCVRVHPVFTVVVSGSEDGSVKVWDHES---GEYIRTLKGHTNTVNGLAFTPT
LIS11_POSPM TSHRAPITRVAFHPTFSLLASASEDTTVKIWDWET---GSFERTLKGHTREVWGVDFDSK
LIS12_POSPM TSHRAPITRVAFHPTFSLLASASEDTTVKIWDWET---GSFERTLKGHTREVWGVDFDSK
LIS1_COPC7 TGHRAPLTSIAFHPQYSILASASEDTTVKIWDWET---GEFERTLKGHTKPVNDLDFDHK
LIS1_CRYNJ ASHRAPVTRLAFHPTWTLLASASEDATVKLWDWEA---GDMERTLKGHTKAVMDVDFDPR
LIS1_USTMA QGHRLPVTKVSFHPVFSQIASASEDTTVKLWDWET---GDFERTLKGHTKAVQDVDFDSK
LIS1_YARLI LLHKQPVNAVSFHPFHSTLASACEDGNIRIWDYEL---GEIETTIKAHTRGVLDVDFSQP
LIS1_CANAW QCE-NIVTTVKLHPNLPLVLNGCNDGNLYIWNISNDDNTIPEKMIKAHTRAINKICFTYK
LIS1_CANAL QCE-NIVTTVKLHPNLPLVLNGCNDGNLYIWNISNDDNTIPEKMIKAHTRAINKICFTYK
LIS1_CANDC QCE-NIVTTVKLHPNLPLVLNGCNDGNLYIWNISNDDNTIPEKMIKAHTRAINKICFTYK
LIS1_CANTT QCE-NVVATVRLHPNLPLVFNGCNDGNLYIWNLTNDDNTIPEKRIKAHTRSINKMCFSYR
LIS1_DEBHA QSH-QLVQSVSIHPALPIILGGCSDGSLIIWNLVNDESLIPEKIIKAHIRGVNTIAWSKK
LIS1_PICST QQN-QLVMASVIHPVLPVIFGGCSDGSIIVWNIVNDDTSIPEKIIRAHTRSINKLAFSVE
LIS1_PICGU QTH-QSVNTVAVHPYLPLIMAGCSDGTLSVWNIANDDPSIPEKSIRAHSRAVNRIRWSNS
LIS1_EREGS DVG-ASVTDIKLHPSLPIAFLATDQGKVVAYDLFN--RSMPLHSTQAHMKGVTSLAV-ME
LIS1_KLULA TLD-ASITALCLHPSLPIIFIGLDSGKLLRYDILN--VELPLQSTMAHMDGITSISISLP
LIS1_LACTC SAG-ASVTSVKLHPELPLVFIATDAGKLQCYDLMN--YTMPVASVQAHMRGITAIDAYVG
LIS1_YEAST NVE-SSVTSVKLHPNLPIVFVATDHGKLYAFDLFN--YTIPLASLQSHTKAITSMDVLFT
LIS1_YEAS7 NVE-SSVTSVKLHPNLPIVFVATDHGKLYAFDLFN--YTIPLASLQSHTKAITSMDVLFT
LIS1_YEAS8 NVE-SSVTSVKLHPNLPIVFVATDHGKLYAFDLFN--YTIPLASLQSHTKAITSMDVLFT
LIS1_YEAS1 NVE-SSVTSVKLHPNLPIVFVATDHGKLYAFDLFN--YTIPLASLQSHTKAITSMDVLFT
LIS1_YEAS2 NVE-SSVTSVKLHPNLPIVFVATDHGKLYAFDLFN--YTIPLASLQSHTKAITSMDVLFT
LIS1_CANGA QNE-SPVTAIKLHPSLAIVYVGTDTGRLIAYDILN--YTIPLAVTTAHSKAITSIEVIEA
LIS1_ZYGRC TLE-SPVTGVRLHPELAVVFVSTEQGRLHCFDLMD--ITLPLASIQAHTRAITSVDVFCW
LIS1_KOMPG MHNGHPVTAIDIHPFQPIMATASQDGTIVIWNLLNL-TEPQQIIRNAHTRSINTIKFMNQ
: .** : :: .* : :
LIS1_AJECG QG--------------------ITMLASCSSDLSVKLWDPAE---GYKNVRTLLGHDHSV
LIS1_AJECH QG--------------------ITMLASCSSDLSVKLWDPAE---GYKNVRTLLGHDHSV
LIS12_ASPCL PGAV------------------GVLLASCSSDLTIKLWDPAD---GYKNIRTLQGHDHIV
LIS11_TALMQ QS--------------------GVLLASCSSDLSIKIWNPLE---DYKNIRTLLGHEHSV
LIS1_TALSN QS--------------------GVLLASCSSDLSIKIWNPSD---DYKNIRTLLGHEHSV
LIS1_ASPFN RD--------------------NVLLASCSSDLSIKLWKPTD---NYKNIRTLQGHDHIV
LIS1_ASPOR RD--------------------NVLLASCSSDLSIKLWKPTD---NYKNIRTLQGHDHIV
LIS12_CHAGB RG--------------------AILLASCSSDSTIKLWDPAD---EYKNTRTLTGHDHSV
LIS1_ARTBC RG--------------------GILLASCSSDLSIKLWDPSN---EYKNIRTLVGHDHSV
LIS1_TRIVH RG--------------------GILLASCSSDLSIKLWDPSN---EYKNIRTLVGHDHSV
LIS1_ARTOC RG--------------------GILLASCSSDLSIKLWDPAN---EYKNIRTLLGHDHSV
LIS1_PYRO7 RG--------------------GILLASCSSDLTIKLWDPSD---DYKNIRTLPGHDHSV
LIS12_UNCRE RS--------------------SILLASCSSDLSIKLWDPAD---EYKNIRTLLGHDHSV
LIS1_GIBZE KG--------------------HTLLASCSSDLTIKLWDPAN---EYQNIRTLPGHDHSV
LIS1_FUSV7 KG--------------------HTLLASCSSDLTIKLWDPSD---EYKNIRTLPGHDHSV
LIS11_CHAGB RG--------------------NTLLASCSSDLTIKLWDPSD---DYKNIRTLPGHDHSV
LIS11_PODAN RG--------------------NTLLASCSSDLTIKLWDPSD---DYKNIRTLPGHDHSV
LIS11_NEUCR RG--------------------NTLLASCSSDLTIKLWDPLD---SYKNIRTLPGHDHSV
LIS11_SORMK RG--------------------NTLLASCSSDLTIKLWDPLD---SYKNIRTLPGHDHSV
LIS1_AJEDR HG--------------------GTLLASCSSDLTIKLWDPSD---EYKNIRTLPGHDHSV
LIS1_BLAGS HG--------------------GTLLASCSSDLTIKLWDPSD---EYKNIRTLPGHDHSV
LIS1_PARBP RG--------------------GTLLASCSSDLTIKLWDPSD---GYKNIRTLPGHDHSV
LIS1_PARBD RG--------------------GTLLASCSSDLTIKLWDPSD---GYKNIRTLPGHDHSV
LIS1_COCP7 RG--------------------GTLLASCSSDLTIKLWDPSD---EYKNIRTLPGHDHSV
LIS1_ASPFU RG--------------------GTLLASCSSDLTIKLWDPSD---NYKNIRTLPGHDHSV
LIS1_NEOFI RG--------------------GTLLASCSSDLTIKLWDPSD---NYKNIRTLPGHDHSV
LIS1_ASPFC RG--------------------GTLLASCSSDLTIKLWDPSD---NYKNIRTLPGHDHSV
LIS11_ASPCL RG--------------------GTLLASCSSDLTIKLWDPSD---DYKNIRTLPGHDHSV
LIS11_PENRW RG--------------------GTLLASCSSDLTIKLWDPAD---EYKNIRTLPGHDHSV
LIS1_SCLS1 RG--------------------GTLLASCSSDLTIKLWDPSD---QYKNIRTLPGHDHSV
LIS1_PHANO RG--------------------GTLLASCSSDLTIKLWDPSD---EYKNIRTLPGHDHSV
LIS1_PYRTR RG--------------------GTLLASCSSDLTIKLWDPSD---EYKNIRTLPGHDHSV
LIS12_NEUCR RG--------------------GTLLASCSSDLTIKLWDPSD---EYKNIRTLPGHDHIV
LIS12_SORMK RG--------------------GTLLASCSSDLTIKLWDPSD---EYKNIRTLPGHDHIV
LIS12_PODAN RG--------------------NTLLASCSSDMSIKLWDPAD---QYKNIRTLHGHDHIV
LIS12_PENRW SS--------------------GILLASCSSDFTIKLWDTTD---DYKNVKTLRGHDHIV
LIS1_ASPTN KG--------------------HTLLASCSGDLTIKLWDPSK---DYANIRTLHGHDHSV
LIS12_TALMQ KG--------------------NTLLASCSSDLTVKLWDPSK---GYANIRTLSGHDHSV
LIS1_EMENI KG--------------------NTLLASCSSDLTIKLWDPSK---DYANIRTLSGHDHSV
LIS1_ASPNC KG--------------------HTILASCSSDLQIKLWDPNK---DYANVRTLSGHDHSV
LIS11_UNCRE KG--------------------RTLLASCSNDLTIKLWDPSN---DYANIRTLFGHDHSV
LIS1_TUBMM KA--------------------GVLLVSCSSDLTIKLWDPNN---EYKNIRTLTGHDHSV
LIS1_PANTR GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_PIG GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_RAT GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_FELCA GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_MOUSE GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_PONAB GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_BOVIN GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_MACFA GK----------------------LLTSCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_HUMAN GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_CHICK GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_XENLA GK----------------------LLASCSADMTIKLWDFQ----GFECLRTMHGHDHNV
LIS1_XENTR GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1B_SALSA GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_TETNG GK----------------------LLASCSADMTIKLWDFQ----SFECIRTMHGHDHNV
LIS1B_DANRE GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1A_SALSA GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1A_DANRE GK----------------------LLASCSADMTIKLWDFQ----GFECIRTMHGHDHNV
LIS1_BRAFL GK----------------------LLASCSADMTIKLWDFQ----TFENIKTMHGHDHNV
LIS1_NEMVE GK----------------------FLASSSADMTIKLWDFQ----GFECIRTLHGHDHNV
LIS1_IXOSC GQ----------------------FLASCSADMTIKLWDFK----SYECLRTMHGHDHNV
LIS1_DROGR GK----------------------LLVSCSADLSIKLWDFQQ---SYECVKTMHGHDHNV
LIS1_DROWI GK----------------------LLVSCSADLSIKLWDFQQ---SYACVKTMHGHDHNV
LIS1_DROVI GK----------------------LLASCSADLSIKLWDFQQ---SYECVKTMHGHDHNV
LIS1_DROAN GK----------------------LLASCSADLSIKLWDFQQ---TYECVKTMHGHDHNV
LIS1_DROPE GK----------------------LLASCSADLSIKLWDFQQ---SYECVKTMHGHDHNV
LIS1_DROPS GK----------------------LLASCSADLSIKLWDFQQ---SYECVKTMHGHDHNV
LIS1_DROMO GK----------------------LLASCSADLSIKLWDFQQ---SYECVKTMHGHDHNV
LIS1_DROER GK----------------------LLASCSADLSIKLWDFQQ---SYECIKTMHGHDHNV
LIS1_DROYA GK----------------------LLASCSADLSIKLWDFQQ---SYECIKTMHGHDHNV
LIS1_DROME GK----------------------LLASCSADLSIKLWDFQQ---SYECIKTMHGHDHNV
LIS1_DROSE GK----------------------LLASCSADLSIKLWDFQQ---SYECIKTMHGHDHNV
LIS1_DROSI GK----------------------LLASCSADLSIKLWDFQQ---SYECIKTMHGHDHNV
LIS1_GLOMM GK----------------------LLASCSADLSIKLWDFQQ---SYDCVKTMLGHDHNV
LIS1_AEDAE GK----------------------LLASCSSDLSIKLWDFQQ---TFECVKTMHGHDHNV
LIS1_TRIAD GK----------------------LLASSSADMTVKIWDFQ----TFECRMTLRGHDHNV
LIS1_CAEBR GK----------------------QLVSCSTDLTIKLWDFGQ---SYDCLKSLKGHEHTV
LIS1_CAEEL GK----------------------QLVSCSSDLSIKLWDFGQ---TYDCLKSLKGHEHTV
LIS1_SCHMA GK----------------------FLASCSADMQVKLWDFT----IYQCIKTLTGHDHNV
LIS1_DICDI GN----------------------LLASCSADLTIKLWDFQ----TYDCVKTLHGHDHNV
LIS1_POLPP GN----------------------LLASCSADLTIKLWDFQ----SFDCIKTLHGHDHNV
LIS1_MONBE GN----------------------RLVSCSTDMTIKVWNMD----NFTCTKTLSGHDHTV
LIS11_PARTE GK----------------------YICSASSDLSIKIWELK----NHTCVKTLIGHEHSV
LIS12_PARTE GK----------------------YICSASSDLSIKLWELK----NHTCVKTLIGHEHSV
LIS1_PHATC GS----------------------HLASCSTDLSIKLWDFQ----TYACIKTLRGHDHTI
LIS11_POSPM GS----------------------FLATCSSDLSIKVWDTQQWDNAGYSGKTLRGHEHTV
LIS12_POSPM GS----------------------FLATCSSDLSIKVWDTQQWDNAGYSGKTLRGHEHTV
LIS1_COPC7 GH----------------------LLVTCSSDLFIKIWDSQ---NEWKNTKTFVGHDHAV
LIS1_CRYNJ GG----------------------LMATCSSDLTLKLWDTA---NQYTNVKTLHGHDHSV
LIS1_USTMA GN----------------------YVLSCSSDLSIKVWDAN---NDYKNIKTLQGHDHSV
LIS1_YARLI DTGASRDKSHDKPRADVSHAQPRALLVSCSSDLTIRIWDPQN---EYANVKTLTGHDHTI
LIS1_CANAW ---------------------KPYYLATCSSDLTIKIWD-EKFNH----IRTLNGHEHTV
LIS1_CANAL ---------------------KPYYLATCSSDLTIKIWD-EKFNH----IRTLNGHEHTV
LIS1_CANDC ---------------------KPYYLATCSSDLTIKIWD-EKFNH----IRTLNGHEHTV
LIS1_CANTT ---------------------KPYYLATCSSDLTIKIWD-EKFNH----IRTLNGHEHTV
LIS1_DEBHA PVDLSG--------KGSEAKGIAHVMATCSSDLSIKIWDGATFKH----IRTLTGHEHTI
LIS1_PICST PADLS----------KDLTKSKTYIFASCSADLSIKIWDSSSYRH----IRTLTGHDHTV
LIS1_PICGU PVELS---------VKAGASNKSYIFASCSSDLSIKIWDGNSNSQ----IRILTGHDHTV
LIS1_EREGS AENG------------------SLLISTTSKDLQCKIW-SFTDNAAFQLLRTLSSHEHIV
LIS1_KLULA NENGR-----------------PAYLATTSKDLNTKIW-ELELDSTLSHIKTLAGHEHTV
LIS1_LACTC EDSQ-------------------CLVATASKDLHCKVF-RFV-DSELQLIRTLSGHEHIV
LIS1_YEAST NYTNS-------------SKKNYLVIVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIV
LIS1_YEAS7 NYTNS-------------SKKNYLVIVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIV
LIS1_YEAS8 NFTNS-------------SKKNYLVVVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIV
LIS1_YEAS1 NFTNS-------------SKKNYLVVVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIV
LIS1_YEAS2 NFTNS-------------SKKNYLVVVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIV
LIS1_CANGA HNFEE-------------FIDSTTLVSTTSKDAQINVYDHSSNTGELKLIRSFNAHDSTV
LIS1_ZYGRC QQT--------------------TYVVTGSKDMQVRVFTWSAGQG-LKLLRSFAGHEHVV
LIS1_KOMPG EVMDGHSTK-----------KNRLLLATGSSDLLIKIWDIED-SANLKALRTLTGHENII
. : * * .:: : .*: :
LIS1_AJECG SAVRFIPCR---------NLLASASRDKDVRIWDVTTGYCVRSIQG-HTGWVRDVCPSFD
LIS1_AJECH SAVRFIPCR---------NLLASASRDKDVRIWDVTTGYCVRSIQG-HTGWVRDVCPSFD
LIS12_ASPCL SAVRFIPNG---------SLLASASRDMDVRLWDVTNGYCVKTIQG-HTGWVRDVCASLD
LIS11_TALMQ SAVRFIPGR---------NLLTSASRDKDLRIWDVTTGFCVKTIQG-HSGWVRDVCPSFD
LIS1_TALSN SAVRFIPGR---------NLLVSASRDKDLRIWDVTTGFCVKTIQG-HSGWVRDVCPSFD
LIS1_ASPFN SAVRFIPSR---------NLLVSASRDNDMRIWDVTTGYCVKTING-HTDWVRDVSISFD
LIS1_ASPOR SAVRFIPSR---------NLLVSASRDNDMRIWDVTTGYCVKTING-HTDWVRDVSISFD
LIS12_CHAGB SAVRFVTSRPR-----SENLLVSASGDKTLKVWDITAGYCIKTLQG-HTGWVRDVVPSLD
LIS1_ARTBC SAVRFIPLGASGAP-SSGNLLASASRDKSLKIWDANTGYCLRTLQG-HTAWVRDVFPSPD
LIS1_TRIVH SAVRFIPLGASGAP-SSGNLLASASRDKSLKIWDANTGYCLRTLQG-HTAWVRDVFPSPD
LIS1_ARTOC SAVRFIPLGASGAP-SSGNLLVSASRDKSLKIWDVNTGYCVRTLQG-HTAWVRDVYPSPD
LIS1_PYRO7 SAIRFMPSGASGAA-MSGNLLVSASRDMTLKIWDVSTGFCLKTIRG-HTAWIRDVYPSLD
LIS12_UNCRE GAVRFIPSGASGTL-SSGNLLVSASRDGTLRIWDVVTGYCVKTLRG-HTAWVRDVCPSFD
LIS1_GIBZE SAVRFIPSGAPGAP-LSGNLLASASRDVTVRIWDVTTGYCVKTIRG-HADWIRDVSPSLD
LIS1_FUSV7 SAVRFIPSGAPGAP-LSGNLLASASRDVTVRIWDVTTGYCLKTIRG-HSDWIRDVSPSLD
LIS11_CHAGB SAVRFIPSGVAG---GAGNLLVSASRDKTLRIWDVSTGYCVKTLRG-HAEWVRDVCPSVD
LIS11_PODAN SAVRFIPSGVAG---GTGNLLVSASRDKTLRIWDVSTGYCVKTLRG-HAEWVRDVCPSID
LIS11_NEUCR SAVRFIP--------GSGNLLVSASRDKTLRIWDVSTGYCVKTLRG-HAEWVRDVCPSLD
LIS11_SORMK SAVRFIP--------GSGNLLVSASRDKTLRIWDVSTGYCVKTLRG-HAEWVRDVCPSFD
LIS1_AJEDR SAVRFIPSGAAGSP-LSGNLLVSASRDKTLRIWDVTTGYCVRTLHG-HVEWVRDVVPSPD
LIS1_BLAGS SAVRFIPSGAAGSP-LSGNLLVSASRDKTLRIWDVTTGYCVRTLHG-HVEWVRDVVPSPD
LIS1_PARBP SAVRFIPSGAAGSP-LSGNLLVSASRDKTLRIWDVTTGYCVKTLRG-HVDWVRDVVASPD
LIS1_PARBD SAVRFIPSGAAGSP-LSGNLLVSASRDKTLRIWDVTTGYCVKTLRG-HVDWVRDVAASPD
LIS1_COCP7 SAVRFIPSGAAGSP-MSGNLLASASRDKTIRIWDVTTGYCVKTIQG-HLDWVRDVFPSPD
LIS1_ASPFU SSVRFIPSGAAGSP-MSGNLLVSASRDKTLRIWDVTTGYCVKTLSG-HVDWVRAVAPSID
LIS1_NEOFI SSVRFIPSGAAGSP-MSGNLLVSASRDKTLRIWDVTTGYCVKTLSG-HVDWVRAVAPSLD
LIS1_ASPFC SSVRFIPSGAAGSP-MSGNLLVSASRDKTLRIWDVTTGYCVKTLSG-HVDWVRAVAPSID
LIS11_ASPCL SSVRFIPSGAAGSP-MSGNLLVSASRDKTLRIWDVTTGYCVKTLSG-HVDWVRAVAPSID
LIS11_PENRW SAVRFIPSGAAGSP-MSGNLLVSASRDLTLRIWDVTTGYCVKSMQG-HGDWIRDVTPSPD
LIS1_SCLS1 SAVRFIPSGAAGSP-SSGNLLVSASRDKTLRIWDVSTGYCVKTVRG-HADWVRDVAPSYD
LIS1_PHANO SAIRFVPSGAAGSP-SSGNLLVSASRDKTLRVWDVTTGYCVKTIRG-HADWVRDVSPSFD
LIS1_PYRTR SAIRFVPSGAAGSP-SSGNLLVSASRDKTLRIWDVTTGYCVKTIRG-HADWVRDVAPSFD
LIS12_NEUCR SSVRFIPSGAAGAP-ASGNLLVSASKDNSLKIWDVTTGYCVKTILG-HVDWPRAVCPSHD
LIS12_SORMK SSVRFIPSGAAGAP-ASGNLLVSASKDNSLKIWDVTTGYCVKTILG-HVDWPRAVCPSHD
LIS12_PODAN SSVRFVPANGT-AG-AGGNLLVSASKDNTLKLWDVTTGYCVKTIEG-HNDWPRAVAPSAD
LIS12_PENRW SAVRFIPSG---------NLLASASRDMKVILWNVINGYRVKTIED-HTGWVRDISPSFD
LIS1_ASPTN SAVRFLTST--------ENLLVSASRDASIRIWDVSTGYCVRTITS-NSIWFLDVSPSFD
LIS12_TALMQ SAVRFLTST--------ENLLVSAGRDASIRIWDVSTGYCVKVLRS-SDAWIRDISSSFD
LIS1_EMENI SSVRFLTSN--------DNHLISASRDGTLRIWDVSTGFCVKVIKSATESWIRDVSPSFD
LIS1_ASPNC SAVRFLRQT--------DNILISASRDATIRIWDVSTGYCVKVIDS-QGSWINDVSPSFD
LIS11_UNCRE SSVRFLIPG--------GNILISASRDTTLRMWDTSTGFCVKTIHT-QGDWVRDVFPSFD
LIS1_TUBMM SAVRFIPSAA-------GEYLVSASRDKTLRVWEVATGYCVKTISG-HSDWIRDVEPSHD
LIS1_PANTR SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_PIG SSVAIMPNG---------DHIVSAARDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_RAT SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_FELCA SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_MOUSE SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_PONAB SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_BOVIN SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_MACFA SSVAIMPNG---------DHLVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_HUMAN SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_CHICK SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_XENLA SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1_XENTR SSVAIMPNG---------DHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQD
LIS1B_SALSA SSVAIMPNG---------DHIVSASRDKTIKMWEVATGYCVKTFTG-HREWVRMVRPNQD
LIS1_TETNG SSVAIMPNG---------DHIISASRDKTMKMWEVATGYCVKTFTG-HREWVRMVRPNQD
LIS1B_DANRE SSVAIMPNG---------DHIVSASRDKTMKMWEVATGYCVKTFTG-HREWVRMVRPNQD
LIS1A_SALSA SSVAIMPNG---------DHIVSASRDKTIKMWEVATGYCVKTFTG-HREWVRMVRPNQD
LIS1A_DANRE SSVAIMPNG---------DHIVSASRDKTIKMWEVATGYCVKTFTG-HREWVRMVRPNQD
LIS1_BRAFL SSVHFMPNG---------DFLISASRDKTIKMWELATGYCVKTFTG-HREWVRTVRVNQD
LIS1_NEMVE SSISFLPSG---------DHLVSASRDKTIKMWEIATGYCVKTFQG-HGEWVRRVRPNAD
LIS1_IXOSC SSVCFLPSG---------DHVVSCSRDKSIKMWEVATGYCVRTFTG-HRDWVRMVRVNSD
LIS1_DROGR SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROWI SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROVI SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROAN SSVAFVPAG---------DYVLSASRDRTVKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROPE SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROPS SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROMO SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROER SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROYA SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROME SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROSE SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_DROSI SSVAFVPAG---------DYVLSASRDRTIKMWEVATGYCVKTYTG-HREWVRMVRVHIE
LIS1_GLOMM SSVAFVPAG---------DYVLSASRDQTIKMWEVATGYCVKTYSG-HREWIRMVRVHMD
LIS1_AEDAE SSVSFVPAG---------DYLLSASRDKTIKMWEVATGYCVKTFTG-HREWVRMVRVNVD
LIS1_TRIAD SSVCFLPSG---------DFLLSSSRDKTIKMWEVATGYCVYNFEG-HREWVRRVAVASD
LIS1_CAEBR SSVTFLPTG---------DFVLSASRDHTIKQWDISTGYCVFTFRG-HNDWVRMIRISHD
LIS1_CAEEL SSVTFLPTG---------DFVLSASRDHTIKQWDISTGYCVYTFRG-HNDWVRMIRISND
LIS1_SCHMA SSVAFLPSG---------DFLVSASRDKTIKMWEVSTGYCTKTFIG-HTEWIRSVRPSPE
LIS1_DICDI SCVRFTPSG---------DQLISSSRDKTIKVWEAATGYCIKTLVG-HEDWVRKITVSED
LIS1_POLPP SCVRFLPSG---------DQLVSSSRDKSIKVWETATGYCTKTLTG-HEDWVRKVIVSED
LIS1_MONBE SSVRFDHTG---------DRVFSASRDKTIKIWELATGYCLQTLQG-HSDWVRSIDVSAD
LIS11_PARTE STVQFSDHG---------DFILSASRDKNIKLWEVATGFCKKTFSE-HQEWVRCAVFSND
LIS12_PARTE STVQFSDHG---------DFILSASRDKSIKLWEVQTGFCKKTFSE-HQEWVRCAVFSND
LIS1_PHATC SSVVFLPFGGDLLTTTKCKRLLSASRDCTVKVWDLETGFCDQTIHD-HNDWVRTLATRAD
LIS11_POSPM STVKFLPGD---------DLIASASRDKTIRIWEVATTFCIRMITG-HEDWVRMTVPSTD
LIS12_POSPM STVKFLPGD---------DLIASASRDKTIRIWEVATTFCIRTITG-HEDWVRMTVPSTD
LIS1_COPC7 SAVRFMPGD---------QLIVSASRDRTIRVFDVASTHQVRTLSG-HSEWVRCVIPSAD
LIS1_CRYNJ SSVRFMPDG---------ETLVSASRDKTIRVWQVSSGYCIKTFSG-HAEWVREAVPSED
LIS1_USTMA SSVRFLPGD---------DYIVSASRDKTIKIWEFSTGFCTKTLQG-HAEWVRSAIPSDD
LIS1_YARLI SAVKFTASG---------NHVISASRDKTVRVWSVQSGYCVRTVHG-HTDWVKSCA-ALN
LIS1_CANAW SSIQFSPV--------DNSILYSVSRDKNIRVWDIFQGISLKSFVG-HSEWCRDLDIISS
LIS1_CANAL SSIQFSPV--------DNSILYSVSRDKNIRVWDIFQGISLKSFVG-HSEWCRDLDIISS
LIS1_CANDC SSIQFSPI--------DNSILYSVSRDKNIRVWDIFQGISLKSFVG-HSEWCRDLDIVSS
LIS1_CANTT SSVKFSPS--------DSNILYSVSRDKNIRVWDISQGVCLKSFVG-HSEWCRDLDAVAS
LIS1_DEBHA SSIVFSAS--------KPNILYSVSRDKSVKVWDLVNGYCIKTFIG-HSDWVRDIDVISV
LIS1_PICST SSVAFSQS--------NPDHLYSVSRDKTVKIWDLVNGYCVKSFTG-HSEWVRDIDVASV
LIS1_PICGU SSIAFSPS--------KPSILYSVSRDKTTKIWDSTNGYCTRTFIG-HSDWVRDLDVIAA
LIS1_EREGS SQSCFLRS-------GSDLLLATCSRDLTVKVWDTKSGWCIKSFQP-HNQWVRTLELH--
LIS1_KLULA SDCQFFER-------GADLLLATCSRDLYLKIWDISNGWCIKSFQP-HTQWIRSLHVH--
LIS1_LACTC SHIKIWNN-------STNTLVASCSRDLTCKVWDIANGWCLKSFQP-HTEWVRCLDVM--
LIS1_YEAST SAVKIWQK-------NNDVHIASCSRDQTVKIWDFHNGWSLKTFQP-HSQWVRSIDVL--
LIS1_YEAS7 SAVKIWQK-------NNDVHIASCSRDQTVKIWDFHNGWSLKTFQP-HSQWVRSIDVL--
LIS1_YEAS8 SAVKIWQK-------NNDVHIASCSRDQTVKIWDFHNGWSLKTFQP-HSQWVRSIDVL--
LIS1_YEAS1 SAVKIWQK-------NNDVHIASCSRDQTVKIWDFHNGWSLKTFQP-HSQWVRSIDVL--
LIS1_YEAS2 SAVKIWQK-------NNDVHIASCSRDQTVKIWDFHNGWSLKTFQP-HSQWVRSIDVL--
LIS1_CANGA SSQKTWQK-------DNDVLLASSSRDATVKVWRVNDSRCLQSFSP-HSEWVKSIDVL--
LIS1_ZYGRC SGVRIWVGPRTTNIGGGSLLLASCSRDTSVKIWDVNSGWCLKSFQP-HSDWVRCLDVY--
LIS1_KOMPG SCLCFHPTE--------PSKLVSCSKDKTTKVWDTRTGSIVLSFVG-HSNWVRSVDINRT
. : : . * : *
LIS1_AJECG ---------------GNFLFSSGDDMTARLWDISAIPNPENKVTMAGHEHFIECCALAPP
LIS1_AJECH ---------------GNFLFSSGDDMTARLWDISAIPNPENKVTMAGHEHFIECCALAPP
LIS12_ASPCL ---------------GRFILSTGDDMTVRLWDISAK--PENKLTMVGHENFNECCAIAPP
LIS11_TALMQ ---------------GNYLFSAGDDVTARLWDITNISNPEAKLTMVGHDHVIECCAVAPQ
LIS1_TALSN ---------------GNYLLSAGDDITARLWDITNISNPEAKLTMVGHDHVIECCAVAPQ
LIS1_ASPFN ---------------GRFLFSTGQDMTARLWDISTVSNIEHKRTMLGHENFIECCAFAPP
LIS1_ASPOR ---------------GRFLFSTGQDMTARLWDISTVSNIEHKRTMLGHENFIECCAFAPP
LIS12_CHAGB ---------------GRFLLSSGTDQTARLWDISAAD-PESKLVMVGHENGIRCCAFAPP
LIS1_ARTBC ---------------GRFLLSTGDDSTARLWDISVS-NPETKVTMFGHDHFNECCAIAPS
LIS1_TRIVH ---------------GRFLLSTGDDSTARLWDISVS-NPETKVTMFGHDHFNECCAIAPS
LIS1_ARTOC ---------------GRFLLSTGDDSTARLWDISVS-NPESKVTMFGHDHFNECCALAPS
LIS1_PYRO7 ---------------GRYLLSTGDDSTVRLWDLSVT-NPENRLTMIGHDHYIECCALAPP
LIS12_UNCRE ---------------GRFLLSAGDDMTTRLWNISGS-NSDHKLTMLGHEHVIECCALAPF
LIS1_GIBZE ---------------GKYLLSTGNDRTVRLWDISVP-NPEAKLVMIGHEHFVECCTFAPP
LIS1_FUSV7 ---------------GKYLLSTGNDRTLRLWDISMN-TPETKMVMIGHEHCVECCAFAPP
LIS11_CHAGB ---------------GRFILSTSDDYTSRLWDVSIA-NPEPKTTLIGHEHVVLCCAIAPS
LIS11_PODAN ---------------GRFILSTSDDYTGRLWDVSIP-NPEPKTTLIGHEHVVLCCAIAPA
LIS11_NEUCR ---------------GKYILSTSDDYTSRLWDVTIT-NPEPKVTLIGHEHVVLCCAIAPP
LIS11_SORMK ---------------GKYILSTSDDYTSRLWDVTVT-NPEPRVTLIGHEHVVLCCAIAPP
LIS1_AJEDR ---------------GRFLFSAGDDRVARLWDVS---SGETKSTFLGHEHFIECVALAPP
LIS1_BLAGS ---------------GRFLFSAGDDRVARLWDVS---SGETKSTFLGHEHFIECVALAPP
LIS1_PARBP ---------------GRFLFSAGNDQVARLWDVS---SGETKSTFLGHEHAVECVAFAPP
LIS1_PARBD ---------------GRFLFSAGNDQVARLWDVS---SGETKSTFLGHEHAVECVAFAPP
LIS1_COCP7 ---------------GRFLMSGGDDRVPRLLDAS---SGETKSTFIGHEHVVECVTIAPA
LIS1_ASPFU ---------------GRFLLAAGDDRIPRLWDLS---SAETKSTFLGHEHVIECVAIAPA
LIS1_NEOFI ---------------GRFLFAAGDDRIPRLWDLS---SAETKSTFLGHEHVIECVAIAPA
LIS1_ASPFC ---------------GRFLLAAGDDRIPRLWDLS---SAETKSTFLGHEHVIECVAIAPA
LIS11_ASPCL ---------------GRFLFAAGDDRIPRLWDLS---AAETRSTFLGHEHVIECVAIAPA
LIS11_PENRW ---------------GRFLFSGGDDRVARLWDIS---SGDTKSTFLGHEHYIECVAFAPP
LIS1_SCLS1 ---------------GRWLLSAGVDQTARIWDAS---SGEPKATLLGHENTIECCVFAPP
LIS1_PHANO ---------------GRWLLSAGNDQTARLWDAS---SGEAKCTFLGHEHVIECVTIAPP
LIS1_PYRTR ---------------GRWLLSAGNDQTARLWDAS---SGEPKCTFIGHEHVVECVTIAPP
LIS12_NEUCR ---------------GRYLLSTGSDKSVRLWDLAGGRDAECRLVMFGHENYNLCCAFAPP
LIS12_SORMK ---------------GRYLLSTGSDKSVRLWDLAGGRDAECRLVMFGHENYNLCCAFAPP
LIS12_PODAN ---------------GRWLLSTGSDKAARLWDI-GGTEPECRVVMFGHENFNLCCEFAPS
LIS12_PENRW ---------------GQFLLSTGDDMTVRLWEISAS-QPICKFTATGHENRILCCAVAPA
LIS1_ASPTN ---------------GKWLVAGGRDQAVTVWEVS---SAEPRAALLGHDNDVQCCVFAPP
LIS12_TALMQ ---------------GKWLVAGGRDQAVTVWEVA---TAEQKSALLGHENYIECCVIAPP
LIS1_EMENI ---------------GKWLVSGGRDQAITVWEVS---SAEPKAALLGHENFIECCVFAPP
LIS1_ASPNC ---------------GKWLVTGGRDQAAMVWEVA---SAKSVASLIGHENFIECCVFAPP
LIS11_UNCRE ---------------GKWLVSGGRDQAATIWEVS---SGEARASLLGHENYIECCTFAPP
LIS1_TUBMM ---------------GRWLLSAGGDQTTRLWDAS---TAEHKATFLGHEHVVNCCVFAPP
LIS1_PANTR ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_PIG ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_RAT ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_FELCA ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_MOUSE ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_PONAB ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_BOVIN ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_MACFA ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_HUMAN ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_CHICK ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_XENLA ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_XENTR ---------------GTLIASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1B_SALSA ---------------GSLIASCSNDQTVRVWVAT---SKECKAELREHEHVVECIAWAPD
LIS1_TETNG ---------------GTLIASCSNDQTVRVWVVA---SKECKAELREHEHVVECISWAPE
LIS1B_DANRE ---------------GTLLASCSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1A_SALSA ---------------GTLIASCSNDQTVRVWVVA---SKECKAELREHEHVVECISWAPE
LIS1A_DANRE ---------------GTLIASSSNDQTVRVWVVA---TKECKAELREHEHVVECISWAPE
LIS1_BRAFL ---------------GSLLASCSNDQTVRVWVVA---NKECKAELREHEHVVECIAWAPE
LIS1_NEMVE ---------------GSLIASCSNDQTIRVWVVA---SRECKCDLRDHDHVIEDLNWAPE
LIS1_IXOSC ---------------GSLLASCSNDQTVRVWVVG---TKECKLELREHDHVVECVAWAPA
LIS1_DROGR ---------------GSIFATCSNDHTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROWI ---------------GSLFATCSNDHTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROVI ---------------GSIFATCSNDHTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROAN ---------------GSIFATCSNDHTIRVWLTN---SRDCKVELRDHEHTVECIAWAPE
LIS1_DROPE ---------------GSIFATCSNDHTIRVWLMN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROPS ---------------GSIFATCSNDHTIRVWLMN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROMO ---------------GSIFATCSNDHTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROER ---------------GSIFATCSNDQTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROYA ---------------GSIFATCSNDQTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROME ---------------GSIFATCSNDQTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROSE ---------------GSIFATCSNDQTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_DROSI ---------------GSIFATCSNDQTIRVWLTN---SKDCKVELRDHEHTVECIAWAPE
LIS1_GLOMM ---------------GNIFASCSIDHSIRIWSIN---SRDCKAELRAHDHTVECIAWAPD
LIS1_AEDAE ---------------GSLMASCSNDHSVRVWQTN---SKECKAELREHENTVECIAWAPE
LIS1_TRIAD ---------------GSLMASCSNDQTVRIWSLS---SKECKEELRGHEHVVECIKWAPE
LIS1_CAEBR ---------------GTLFASGSLDQTVSVWSLP---RKQ-----RNWYFEIMSMRWSVS
LIS1_CAEEL ---------------GTLFASASLDQTVTVWSFA---TKSAKLVLRDHEHAVECVEWAPD
LIS1_SCHMA ---------------GNLLASCSNDHTIRIWSVE---SRECQVVLRGHEHVVECIAWASH
LIS1_DICDI ---------------GSCIASCSNDQTIKTWNIV---KGECLATYREHSHVVECLAFSTA
LIS1_POLPP ---------------GTTLASCSNDQTARVWNLA---KGECLLTFREHSHVVECLAYSPA
LIS1_MONBE ---------------GAWICSASSDHTVRVWSVA---SGECKHVWSDHEHVVEHASFAPL
LIS11_PARTE ---------------EKQIASCSQDQMIYIWVID---SGQVLHQLSGHEHVVEQVKYIPE
LIS12_PARTE ---------------EKQMASCSQDQMIYIWVID---SGQILHQLSGHEHVVEQVKYVPE
LIS1_PHATC ---------------GSVWASAGNDTVIYVYEQD---RMKKAVELRGHEQVVESIAFLTQ
LIS11_POSPM ---------------GTLLGSCSSDNTARVWDPT---SGVMKMEFRGHGHIVEVIAFAPL
LIS12_POSPM ---------------GTLLGSCSSDNTARVWDPT---SGVMKMEFRGHGHIVEVIAFAPL
LIS1_COPC7 ---------------GTMLASGSKDQTVRLWDPL---TGEPKSELRGHENDVEAVAFAPI
LIS1_CRYNJ ---------------GRWLVSASNDQTSRIWDFS---TGETKMELRGHEHVVECAVFAPV
LIS1_USTMA ---------------AKWLVSCSTDQTARVWDVS---SGETKVELRGHEHVVEVAIFAPV
LIS1_YARLI ---------------EEFIFSAGIDHVTRVSEFVS---GDGKMTLLGHEHVIEGVAVYPK
LIS1_CANAW DTY------------GDFVLTCSNDQSARLSHAN---SGAGVAMIVGHSHVVETVKFLPS
LIS1_CANAL DTY------------GDFVLTCSNDQSARLSHAN---SGAGVAMIVGHSHVVETVKFLPS
LIS1_CANDC DNN------------GDFVLTCSNDQSARLSHAS---SGAGLAMIVGHGHVVETVKFLPA
LIS1_CANTT ETQ------------GDFVLTCSNDQSARLSHIN---SGVGVAMFVGHTHVVESVKFLPK
LIS1_DEBHA NSNLLQEQSDINPELGDFLVTCSNDQSIRLSHAE---SGTGLSLSIGHTHVIECVKFLP-
LIS1_PICST NSQLSLNNMKVSAELGDFVVTCSNDQSVRVSHAE---SGAGLALLIGHTHVIEKVKFLP-
LIS1_PICGU KQK----------SLGDFILTCSNDQSVRLSHAD---SGTGLCLLVGHSHVIESVRFLP-
LIS1_EREGS ---------------GDYVITGSNDATIRLSHWP---SGNGLSMAVMHEFPIERVLIIPM
LIS1_KLULA ---------------GEFVLTGSNDSAIRLTHWP---SGNGLSMGIGHDFPVEKVLILIP
LIS1_LACTC ---------------GDFVVTGSNDCTVRLSHWP---TGRSLSFGTGHEFPVEKIRIIPL
LIS1_YEAST ---------------GDYIISGSHDTTLRLTHWP---SGNGLSVGTGHEFPIEKVKFIHF
LIS1_YEAS7 ---------------GDYIISGSHDTTLRLTHWP---SGNGLSVGTGHEFPIEKVKFIHF
LIS1_YEAS8 ---------------GDYIISGSHDTTLRLTHWP---SGNGLSVGTGHEFPIEKVKFIHF
LIS1_YEAS1 ---------------GDYIISGSHDTTLRLTHWP---SGNGLSVGTGHEFPIEKVKFIHF
LIS1_YEAS2 ---------------GDYIISGSHDTTLRLTHWP---SGNGLSVGTGHEFPIEKVKFIHF
LIS1_CANGA ---------------DEYILSGSLDSTLRLTHWP---SGNGLSVGTGHEFPIERVLIIPF
LIS1_ZYGRC ---------------GEFLITGCQDSTLRLTHWP---SGNGLSVGLGHDFPVESVRFIGS
LIS1_KOMPG ---------------GEFTLTSSNDHSIRLSSLL---TGTGIGLMIGHEQVVEKVKFLPM
: *
LIS1_AJECG TSYQYLAPVAGLK----------GPSYPK-----SAAEFMATGSRDKTIKVWDVR-----
LIS1_AJECH TSYQYLAPVAGLK----------GPSYPK-----SAAEFMATGSRDKTIKVWDVR-----
LIS12_ASPCL TSYQYLAPLARLA----------KVSRAG-----STAEFMATGSRDKTIKLWDAR-----
LIS11_TALMQ TSYQYLAPMAGLK----------KEALSKM----SAVEFTATGSRDKTIKVWDRR-----
LIS1_TALSN TSYQYLAPMAGVK----------KEAVSKL----GAVEFIATGSRDKTIKVWDRR-----
LIS1_ASPFN TSYQFLAPLAGLG----------KRPSST-----NGADFMATGSRDNTIKIWDSR-----
LIS1_ASPOR TSYQFLAPLAGLG----------KRPSST-----NGADFMATGSRDNTIKIWDSR-----
LIS12_CHAGB ASYVHMAALAGLK----------KPPPST-----STAEFMATGSRDKTIKLWNST-----
LIS1_ARTBC TSYQYLSPLTGLK----------KPPPAS-----STAEFMATGSRDKKIKIWDAR-----
LIS1_TRIVH TSYQYLSPLTGLK----------KPPPAS-----STAEFMATGSRDKKIKIWDAR-----
LIS1_ARTOC SSYQYLSPLTGLK----------KPPAAS-----STAEFMATGSRDKTIKLWDAR-----
LIS1_PYRO7 SSYPFLSRLAGLK----------KPPAAT-----STAEFMASGSRDKTIKLWDAR-----
LIS12_UNCRE ASYQYLAALTGLK----------APP-AS-----SAAEFMATGSRDKTIKLWDAH-----
LIS1_GIBZE AAYSHLATLAGVK----------KPPPAS-----STAEFMATGGRDKTIRLWDGR-----
LIS1_FUSV7 TSYQHLATMAGLK----------KAPPAS-----STAEFMATGSRDKTIRLWDSR-----
LIS11_CHAGB ASYPHLAAIAGVK----------KPP-TT-----SAVEFMATGSRDKTIRLWDAR-----
LIS11_PODAN AAYPHLAAMAGIK----------KPP-AT-----SAVEFMATGSRDKTIRLWDAR-----
LIS11_NEUCR AAYQNLAAMAGIK----------KPP-AT-----SSAEFMATGSRDKSIRLWDAR-----
LIS11_SORMK AAYQNLAAMAGIK----------KPP-AT-----SSAEFMATGSRDKSIRLWDAR-----
LIS1_AJEDR TTYPYLAALAGLK----------KPPPPS-----SSAEYVATGSRDKTIRVWDSR-----
LIS1_BLAGS TTYPYLAALAGLK----------KPPPPS-----SSAEYVATGSRDKTIRVWDSR-----
LIS1_PARBP TSYPHLAALAGLK----------KAPPSS-----SSAEYVATGSRDKSIRIWDAR-----
LIS1_PARBD TSYPHLSALAGLK----------KAPPSS-----SSAEYVATGSRDKSIRIWDAR-----
LIS1_COCP7 ASYPHLAALAGLK----------KPPPAS-----SSAEFVATGSRDKTIKIWDSR-----
LIS1_ASPFU ASYPHLAVLSGLK----------KPPPAS-----SSAEFFATGSRDKTIRLWDSR-----
LIS1_NEOFI ASYPHLAVLSGLK----------KPPPVS-----SSAEFFATGSRDKTIRLWDSR-----
LIS1_ASPFC ASYPHLAVLSGLK----------KPPPAS-----SSAEFFATGSRDKTIRLWDSR-----
LIS11_ASPCL ASYPHLAVLSGLK----------KPPSAS-----SSAEFFATGSRDKTIRLWDSR-----
LIS11_PENRW TSYPHFAALAGLK----------KPPPAS-----SSAEFVATGSRDKTIRLWDTR-----
LIS1_SCLS1 ASYPHLAAMAGLK----------KPPAAS-----SSAEYIATGARDKSIRIWDAR-----
LIS1_PHANO VSYANLASLAGLK----------KPPPLS-----SSAEFVATGSRDKTIKIWDGR-----
LIS1_PYRTR VSYANLASLAGLK----------KPPPLS-----SSAEYIATGSRDKTIKIWDGR-----
LIS12_NEUCR TAYPHLAKLAGLE----------RAPPPS-----SSAEFMATGSRDKQIRLWDGR-----
LIS12_SORMK TAYAYLAKLAGLD----------RPPPLG-----ASAEFMATGSRDKQIRLWDGR-----
LIS12_PODAN TSYPHLARLAGHE----------KVPPAN-----SAAEFMATGSRDKQIRLWDRR-----
LIS12_PENRW TSFRYLASFLESR----------GSTIAA--------EITATGSRDKSIKLWDSH-----
LIS1_ASPTN ASYEYLATLAGHK----------KAPLAS-----SSSEFIATGSRDKTIKLWEAR-----
LIS12_TALMQ TSYEHLATLAGLK----------KPPAPS-----SSCEFIATGARDKTIRLWESR-----
LIS1_EMENI ASYEHLATLAGLK----------KPPPAT-----SSCEFVATGARDKTIKLWEAR-----
LIS1_ASPNC SSYKHLAAIAGLK----------TAPPAS-----SSSEFIATGARDKTIKLWESR-----
LIS11_UNCRE SSYGYLATLAGLK----------KPPSTN-----SSAEFVATGARDKTVKLWDSR-----
LIS1_TUBMM SSYPHLATIAGLK----------KPPPAT-----SSSEFIATGSRDKTIKLWDAR-----
LIS1_PANTR SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_PIG SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_RAT SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_FELCA SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_MOUSE SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_PONAB SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_BOVIN SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_MACFA SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_HUMAN SSYSSISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1_CHICK SSYSTISEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDIST----
LIS1_XENLA SSYSTISDATGSE-------TKRSGKPGP---------FLLSGSRDKTIKMWDISI----
LIS1_XENTR SSYSTISDATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDISI----
LIS1B_SALSA TAHPTILEATSSE-------SKKNGKSGP---------FLLSGSRDKTIKMWDIST----
LIS1_TETNG SAHPTILDATSSE-------SKKSGKPGP---------FLLSGSRDKTIKMWDVST----
LIS1B_DANRE SAHPTISEATGSE-------NKKSGKPGP---------FLLSGSRDKTIKMWDIST----
LIS1A_SALSA SAHPTILEATGSE-------SKKSGKPGP---------FLLSGSRDKTIKMWDVSI----
LIS1A_DANRE SAHPTILEATGSE-------TKKSGKPGP---------FLLSGSRDKTIKMWDVSI----
LIS1_BRAFL SCNGHVSEVMGAE-------KK--GRSGP---------FLLSGSRDKTIKMWDIST----
LIS1_NEMVE SATPVINEAAGVEG------GKKAMSPGP---------FLVSASRDKSIKIWDVSA----
LIS1_IXOSC HAQLCGAAGDSNRRPG----AGGAQGTGP---------FLVSGSRDKTIKVWDVST----
LIS1_DROGR AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROWI AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROVI AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROAN AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROPE AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROPS AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROMO AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROER AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROYA AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROME AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROSE AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_DROSI AAASAINEAAGAD-------NKKGHHQGP---------FLASGSRDKTIRIWDVSV----
LIS1_GLOMM ISTTHINEAAGSD-------NKKGHHQGP---------FLASGSRDKTIRVWDVGV----
LIS1_AEDAE SAAAAINEAAGAD-------NKKGAHQGP---------FLASGSRDKTIRVWDVNS----
LIS1_TRIAD SCNRYINEASGTE-------VPKGQKSGP---------FLASGSRDRVIKIWDVTT----
LIS1_CAEBR ---------------------KPEGNSTH---------ILFSGSRDRSIKAWNIST----
LIS1_CAEEL TAYTNVTG------------QQPEGNSTH---------ILFSGSRDRSIKAWNINT----
LIS1_SCHMA PQNLNS--------------LPSSMNSSL---------LLVSGSRDRTIRFWDVNI----
LIS1_DICDI NIIDIPGSLLSTPE------GKSKVKQGPGGNLVGQCGYLATGSRDKTIKIWELAT----
LIS1_POLPP NIVEVPGSLLSTPE------GKAKAKAGAGGTSFGQAGYLATGSRDKTIKIWELAT----
LIS1_MONBE VAHEALNLMIFGSKP-----SAEAASKGP---------FVASASRDKSICLFDVST----
LIS11_PARTE HGAKQILTQQQQQ----------NIQTI---------NLLVSVSRDKEIKIWNTIL----
LIS12_PARTE HGAKQILTQQQQQ----------NIQTI---------NLLVSVSRDKEIKIWNTIL----
LIS1_PHATC DTIPKNNAQRPSK----------HIETVR--------DYLVSGSRDRTVRLWKVSE----
LIS11_POSPM ASYAAIRELAGL----------KAATKAPG-------AYIATGSRDKTVKIWDVHS----
LIS12_POSPM ASYAAIRELAGL----------KAATKAPG-------AYIATGSRDKTVKIWDVHS----
LIS1_COPC7 SAYAAIRELAGIP---------NDRTKRHG-------LFLASGARDKTVKLWDTQT----
LIS1_CRYNJ NAYPAIRELAGLKPPA----PRDTRAKSPG-------VYAATGSRDKTIKLWDALS----
LIS1_USTMA ASYAAIRQLASLDPNA----SKDASASMAG-------QFVATGSRDKTIRIWDSIS----
LIS1_YARLI SAAGCLAKLDKTS-----------------------SYFVVSWSRDKTIRVWSSR-----
LIS1_CANAW LQANKILDEYITKNTEQFPTIPLELLKDKTYNQ-LGFKYCITASRDNTIKLWLIPPPTIA
LIS1_CANAL LQANKILDEYITKNTEQFPTIPLELLKDKTYNQ-LGFKYCITASRDNTIKLWLIPPPTIA
LIS1_CANDC LQANKILDEYITKNIEQFPTIPLELLKDKTYNQ-LGFKYCITASRDNTIKLWLIPPPKIA
LIS1_CANTT IQANELIDEYITKNIDQFPSIPSELLKDPIYDE-LGFKYCVSASRDNTIKLWLIPPPTLI
LIS1_DEBHA FHSNYIIDKYIKENESLFPNISPEVLDDPNYTNLLGYKYCISGGRDNSVKLWLLPPPVFR
LIS1_PICST AVSNTILDKFLKENHAQFPSIPQELVSDEIFTTTLGYKYCISGGRDNLLKLWLIPPPTLI
LIS1_PICGU MHSNAHIDKYLKENSDRFPSMPPELVSAPIYDDVLGYKYCVSAGRDNIVKLWLMPPAVVR
LIS1_EREGS RANTAQKTEADD------DQVELEYRKYDPDYSPLGFKYCISCSRDNLIVLWKIPLPKFI
LIS1_KLULA -----------------------DPQHLQPQYQPLGFQHVASASRDGTIRLWKVSLPKFI
LIS1_LACTC QP-------PES------AEHSHRFNTHDEDYLPLGFSHVISTSRDGTLRIWQVPLPRFV
LIS1_YEAST IED---------------SPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLM
LIS1_YEAS7 IED---------------SPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLM
LIS1_YEAS8 IED---------------SPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLM
LIS1_YEAS1 IED---------------SPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLM
LIS1_YEAS2 IED---------------SPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLM
LIS1_CANGA SDSKI-------------CTSPYRDQNEHSAFAPLRFKYCASAARDNTIKIWEVPLPQLK
LIS1_ZYGRC LQD----------------------AVTTEGRTNNWLGHCVSTSRDRTSKIWLLPQPRRL
LIS1_KOMPG ACNKYLDHIAGVK-------FQNELKINDDNYNKVDYKYCISGGRDNSVCIWLLPLPLIR
: .** :
LIS1_AJECG --------------GTCLMTLIGHDNWVRGIVFHPAGKYLLSVSDDRTLRCWDL----SQ
LIS1_AJECH --------------GTCLMTLIGHDNWVRGIVFHPAGKYLLSVSDDRTLRCWDL----SQ
LIS12_ASPCL --------------GTCLMTLTGHDNWVRAIVFHPGGRYLLSVSDDKTLRCWDL----SQ
LIS11_TALMQ --------------GSCLMTLVGHDNWVRAIVFHPGGKYLLSASDDKSIRCWDL----SQ
LIS1_TALSN --------------GSCLMTLVGHDNWIRAIVFHPGGKYLLSSSDDRSIRCWDL----SQ
LIS1_ASPFN --------------GTCLMTLVGHDSWVQALVFHPGGKYLLSVSDDKTLRCWDL----NQ
LIS1_ASPOR --------------GTCLMTLVGHDSWVQALVFHPGGKYLLSVSDDKTLRCWDL----NQ
LIS12_CHAGB --------------GTCIKTLVGHDNWVSGLVFHPGGKYLLSVADDKTLRCWDL----GD
LIS1_ARTBC --------------GTCLLTLAGHDNWIRALAFHPGGKYLFSVSDDRTLRCWDL----SQ
LIS1_TRIVH --------------GTCLLTLAGHDNWIRALAFHPGGKYLFSVSDDRTLRCWDL----SQ
LIS1_ARTOC --------------GTCLMTLVGHDNWIRALAFHPGGKYLFSVSDDRTLRCWDL----SQ
LIS1_PYRO7 --------------GTLLKTLIGHDNWVRALVFHPGGRYLLSVSDDKTLRCWDL----EQ
LIS12_UNCRE --------------GRCLGTLIGHDNWVRALAFHPGGKYLLSVSDDKTLRCWDL----SQ
LIS1_GIBZE --------------GNCIKTLIGHDNWVRGLVFHPSGKFLLSVSDDKTIRCWDL----SQ
LIS1_FUSV7 --------------GTCIKTLIGHDNWVRSLVFHPSGKFLLSVSDDKTIRCWDL----SQ
LIS11_CHAGB --------------GTCIKILVGHDNWVRGLVFHPGGKYLLSASDDYTLRCWDL----TQ
LIS11_PODAN --------------GTCIKILVGHDNWVRGLVFHPGGQYLLSVADDYTLRCWDL----TQ
LIS11_NEUCR --------------GTCIKTLVGHDNWVRGLVFHPGGKYLLSVSDDKTLRCWDL----TQ
LIS11_SORMK --------------GTCIKTLAGHDNWVRGLVFHPGGKYLLSVSDDKTLRCWDL----TQ
LIS1_AJEDR --------------GTLIKTLIGHDNWVRALVFHPGGKYLLSVSDDKTIRCWDL----SQ
LIS1_BLAGS --------------GTLIKTLIGHDNWVRALVFHPGGKYLLSVSDDKTIRCWDL----SQ
LIS1_PARBP --------------GTLIKTLIGHDNWVRALAFHPGGKYLLSVSDDKTLRCWDL----TQ
LIS1_PARBD --------------GTLIKTLIGHDNWVRALAFHPGGKYLLSVSDDKTLRCWDL----TQ
LIS1_COCP7 --------------GTLIKTLVGHDNWIRALVFHPGGKYLLSVSDDKTLRCWDL----SQ
LIS1_ASPFU --------------GNLIKTLVGHDNWVRALAFHPGGKHLLSVADDKTIRCWDL----TQ
LIS1_NEOFI --------------GNLIKTLVGHDNWVRALAFHPGGKHLLSVADDKTIRCWDL----TQ
LIS1_ASPFC --------------GNLIKTLVGHDNWVRALAFHPGGKHLLSVADDKTIRCWDL----TQ
LIS11_ASPCL --------------GNLIKTLVGHDNWVRALAFHPGGKYLLSVSDDKTIRCWDL----TQ
LIS11_PENRW --------------GNCIKTLVGHDNWVRSLVFHPGGKYLLSVSDDKTLRCWDL----TQ
LIS1_SCLS1 --------------GTLIKTLIGHDNWIRALVFHPGGKYLLSVADDRTLRCWDL----AQ
LIS1_PHANO --------------GTLIKTLAGHDNWVRALIFHPGGKYLLSASDDKTIRCWDL----TQ
LIS1_PYRTR --------------GTLIKTLTGHDNWIRSLVFHPGGKYLLSASDDKTIRCWDL----TQ
LIS12_NEUCR --------------GNCIKVLVGHDNWVRGLVFHPGGKYLLSVADDRTMRCWDL----SQ
LIS12_SORMK --------------GNCVKVLVGHDNWVRGLVFHPGGKYLLSVADDRTMRCWDL----SQ
LIS12_PODAN --------------GQCIKVLEGHDNWVRGLAFHPAGKFLISVADDRTMRCWDL----SQ
LIS12_PENRW --------------GRCIMTLTGHASWVRAIAFHPGGKYLLSVSDDKTMRCWDL----SQ
LIS1_ASPTN --------------GRLIKTLVGHDNWIRGLVFHPSGKYLFSVSDDKTIRCWDL----SQ
LIS12_TALMQ --------------GRLIKTLVGHDNWVRDLVFHPNGKHLISVADDKTIRCWDL----SQ
LIS1_EMENI --------------GRLIKTLHGHDNWVRGLVFHPGGKYLFSVSDDKTIRCWDL----SQ
LIS1_ASPNC --------------GRLIKTLVGHDNWVRGLLFHPGGKYLISVADDKTIRCWDL----SQ
LIS11_UNCRE --------------GSLIKTLIGHNNWVRGLVFHPGGKYLFSVGDDKTIRCWDL----SQ
LIS1_TUBMM --------------GTLLKTLVGHDNWIRALAFHPAGKYLLSVSDDKTIRCWDL----TQ
LIS1_PANTR --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_PIG --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_RAT --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_FELCA --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_MOUSE --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_PONAB --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_BOVIN --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_MACFA --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_HUMAN --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY----KN
LIS1_CHICK --------------GMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDF----KN
LIS1_XENLA --------------GMCLMTLVGHDNWVRGVQFHPGGKFILSCADDKTIRIWDY----KN
LIS1_XENTR --------------GMCLMTLVGHDNWVRGVQFHPGGKFILSCADDKTIRIWDY----KN
LIS1B_SALSA --------------GMCLMTLVGHDNWVRGVLVHPGGRFIVSCADDKTLRIWDY----KN
LIS1_TETNG --------------GMCLMTLVGHDNWVRGVLFHPGGKFIVTCADDKTLRIWDY----KN
LIS1B_DANRE --------------GMCLMTLVGHDNWVRGVLFHPGGRFVVSCADDKTLRIWDY----KN
LIS1A_SALSA --------------GMCLMTLVGHDNWVRGMLVHPGGKFILSCADDKTLRIWDY----KN
LIS1A_DANRE --------------GMCLMTLVGHDNWVRGVLVHPGGKYIVSCADDKTLRIWDY----KN
LIS1_BRAFL --------------GVCIMTLVGHDNWVRGVVWHPGGKYIISASDDKTIRVWDY----KN
LIS1_NEMVE --------------GVCLVTLVGHDNWVRAVMFHPGGKFIVSCSDDKTLRIWDY----KN
LIS1_IXOSC --------------GLALFTLVGHDNWVRGVKFHPGGKYLLSASDDKTLRVWEL----AH
LIS1_DROGR --------------GQCLLTLNGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROWI --------------GLCLLTLNGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROVI --------------GQCLLTLNGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROAN --------------GLCLFTLNGHDNWVRGLAFHPAGKYLVSASDDKTIRVWDL----RN
LIS1_DROPE --------------GLCLLTLNGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROPS --------------GLCLLTLNGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROMO --------------GLCLLTLNGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROER --------------GLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROYA --------------GLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROME --------------GLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROSE --------------GLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_DROSI --------------GLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_GLOMM --------------GLCLFVLTGHDNWVRELTFHPGGKYLVSASDDKTIRVWDL----RN
LIS1_AEDAE --------------GLCLFTLVGHDNWVRGIVFHPGGKYMLSASDDKTLRIWDL----RN
LIS1_TRIAD --------------AVCLFSLVGHDNWVRGLAFHAGGKYLTSASDDKTIKIWEL----RH
LIS1_CAEBR --------------GEVIFTLSAHENWVRGLAFHPKGKYLVSVADDKMMRIWEL----SA
LIS1_CAEEL --------------GDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWEL----SA
LIS1_SCHMA --------------GICLFVLIGHDNWVRQLVFHPHGRLLLSASDDKTIRVWDL----KN
LIS1_DICDI --------------GRCLATYIGHDNWVRAVRFHPCGKFLLSVGDDKTIRVWDI----AQ
LIS1_POLPP --------------GRCLQTYIGHDNWVRSIKFHPCGKYLISVGDDKSIRVWDI----AQ
LIS1_MONBE --------------GQHLARLTGHDNWVRATAWSRGGRYLFSVADDKTMRVWDI----AT
LIS11_PARTE --------------GTNLFTLSGHDNWVNGVSFHPDGVHMLSVSDDKTIRVWNL----KE
LIS12_PARTE --------------GTNLFTLSGHDNWVNGVSFHPDGVHMLSVSDDKTIRVWNL----KE
LIS1_PHATC --------------ASCLMVLKAHDNWVRSVLIHPNGNYILSSSDDKSIRVFDI----KN
LIS11_POSPM --------------GQELRTLSGHNDWIRGLVFHPSGKHLLSASDDKTIRVWEL----ST
LIS12_POSPM --------------GQELRTVSGHNDWIRGLVFHPSGKHLLSASDDKTIRVWEL----ST
LIS1_COPC7 --------------GQMIRNLAGHDNWVRALAFHPSGKYLLSSSDDKTVRVWEL----ST
LIS1_CRYNJ --------------GQCLRTLVGHDNWIRALVFHPSGKYLLSASDDKTIKVWDL----AN
LIS1_USTMA --------------GQCLKTLTGHDNWVRGLAFSPNGKSLLSVSDDKTMRLWDL----QS
LIS1_YARLI --------------GDPLLILRGHDNWVRGVVLHPAGRYLVSVSDDKTMRCWDL----EQ
LIS1_CANAW PHRPPLPSKYNNSQSWLIAELKGHSSWVKSLCVHPNGKFIISGSDDKTIKFWDLSGLLET
LIS1_CANAL PHRPPLPSKYNNSQSWLIAELKGHSSWVKSLCVHPNGKFIISGSDDKTIKFWDLSGLLET
LIS1_CANDC PHRPPLPSKYNNSQSWMIAELRGHSSWVKCLCVHPNGRFIISGSDDKTIKFWDLSSLLET
LIS1_CANTT PHRSPLPSKYNNSQGWLIAEFKGHSSWVKCLSVHPNGKFIISGSDDKTIKFWDLSGLIET
LIS1_DEBHA PHRHPLPSQLNNSQGWLIADLVGHQSWVKSLHIHPNGRFVFSGSDDKTIKIWDLSSLNVN
LIS1_PICST PHRSPLPAQHNNSQGWAIADLVGHQSWVKAIAIHPNGRFIFSGSDDKTIKVWDLANLNVT
LIS1_PICGU PNAHPLPAATNNSQGWHIADLTGHQSWVKTLQVHPNGRFIFSAGDDKSIRVWDLSTLATG
LIS1_EREGS PHRPPQPNLLQTNF-EKVHVFKGHTSWVRDIKVR--GRHLFSCSDDRSIRCW-----DLV
LIS1_KLULA PHRPPRPNPLDTTF-KVIAVLTDHNSWVRDLRQF--NDMLFSCSDDGSVKCWSLDWTNLS
LIS1_LACTC AHRAPQPNPARPYF-NLVATLKGHSSWVRDVRVR--GKHAFSCSDDRSIKVW-----DLS
LIS1_YEAST AHRAPIPNPTDSNF-RCVLTLKGHLSWVRDISIR--GQYLFSCADDKSVRCW-----DLN
LIS1_YEAS7 AHRAPIPNPTDSNF-RCVLTLKGHLSWVRDISIR--GQYLFSCADDKSVRCW-----DLN
LIS1_YEAS8 AHRAPIPNPTDSNF-RCVLTFKGHLSWVRDISIR--GQYLFSCADDKSVRCW-----DLN
LIS1_YEAS1 AHRAPIPNPTDSNF-RCVLTLKGHLSWVRDISIR--GQYLFSCADDKSVRCW-----DLN
LIS1_YEAS2 AHRAPIPNPTDSNF-RCVLTLKGHLSWVRDISIR--GQYLFSCADDKSVRCW-----DLN
LIS1_CANGA PNSAPVPSTTNTTF-KCVMTLRGHTSWVKDLKLR--GDHLFSCSDDETIKCW-----DLN
LIS1_ZYGRC PQRPPVPHSTDAQF-LCKWTLRGHDSWIKAVGSR--GDHVFTASDDKSVICW-----NWT
LIS1_KOMPG SDGTMHPSTNPE--GKLILKLTEHKSWVKDIAIHPNSRFIISVGDDRKINIWDL-GLLLE
* .*: . : .** : :
LIS1_AJECG EGKCVKTIKDAHDRFVTCLSWAPGVAKDVPAIPSNTAKGE---SSEIKETLKS-------
LIS1_AJECH EGKCVKTIKDAHDRFVTCLSWAPGVAKDVPAIPSNTAKGE---SSEIKETLKS-------
LIS12_ASPCL EGKCVKTIRDTHGGFITCLRWAPAILKDTPTDAARALVRQ---IPDVAEIMKNA------
LIS11_TALMQ DGKCVKTLSDAHGRFVTCLRWAPSVVKEVAPSAESANGQ-----TDTNDLLKS-------
LIS1_TALSN DGKCVKTLSEAHGHFISSLRWAPNVVKEVANNADSGNGK-----TDSNGLLKG-------
LIS1_ASPFN QGKCVKTL-DAHESFVTSLRWAPGVAKNVPGGDGAAEGEG---NDKNGAGSEN-------
LIS1_ASPOR QGKCVKTL-DAHESFVTSLRWAPGVAKNVPGGDGAAEGEG---NDKNGAGSEN-------
LIS12_CHAGB DGRCVKVLADAHGQFITCLRWAPGIVKKGADQGA----------EDTGPLEKT-------
LIS1_ARTBC EGKCIKVMRDAHERFITCLRWAPSIFK-DAPTGNGAS------DGKNGD-----------
LIS1_TRIVH EGKCIKVMRDAHERFITCLRWAPSIFK-DAPTGNGAS------DGKNGD-----------
LIS1_ARTOC EGKCIKVMRDAHERFITCLRWAPSIFK-DTPTGHGAG------DGRNGD-----------
LIS1_PYRO7 DGKCVKTIGDVHERFVTCLRWAPGVVM-DAPAEADGQ------SNGTPR-----------
LIS12_UNCRE GGKCVKTLKDAHERFITCLRWAPGIFK-NVPGVSTRD------ANGESNGVLNT------
LIS1_GIBZE EGKCVKTVEGSHEHFITSLRWAPPIIKDKGPGEETNG------DVGTPK-----------
LIS1_FUSV7 EGKCVKTLEGMHEHFITSLRWAPPIT--KGPADEANG------EIGTPK-----------
LIS11_CHAGB EGRCVKTISDAHAHFVQCIRWAPSVVKDVSVANGGDG------QGGEANGTPRQ------
LIS11_PODAN EGRCVKTIGDAHGHFVQCIRWAPSIVKDVPAVNG-EG------ANGESNGTPRK------
LIS11_NEUCR EGKCVKTIGDAHGHFVQCIKWAPSVIKDASVNGD----------NGEPNGTPKK------
LIS11_SORMK EGKCVKTIGDAHGHFVQCIRWAPSVIKDVSVNGD----------NGEPNGTPKK------
LIS1_AJEDR EFKCVRVVTDAHA-FVTCIRWAPNIIKDAGGMGVNGDING----GGSLALSGVNGIIPGS
LIS1_BLAGS EFKCVRVVTDAHA-FVTCIRWAPNIIKDAGGMGVNGDING----GGSLALSGVNGIIPGS
LIS1_PARBP ECKCVRTVKDAHGHFISCIRWAPNIIKDAGVVNGDDTSTAASANGGALGASAINGVVPTG
LIS1_PARBD ECKCVRTVKDAHGHFISCIRWAPNIIKDAGVVNGDDTSTAASANGGALAASAINGVVPTG
LIS1_COCP7 ECKCVRTVSDAHGHFVSCIRWAPNIINESGLVSGEGGING----QGTPSMNGVS-ISTTS
LIS1_ASPFU ECKCVRVISDAHGHFVTCLRWAPPLIKDGGANGEAE-------TNGTPAATSTT----NG
LIS1_NEOFI ECKCVRVISDAHGHFVTCLRWAPPLIKDGGANGESE-------TNGAPAATATT----NG
LIS1_ASPFC ECKCVRVISDAHGHFVTCLRWAPPLIKDGGANGEAE-------TNGTPAATSTT----NG
LIS11_ASPCL ECKCVRTIADTHEHFVTCLRWAPPLIKDSGANGDAG-------ANGTPAATTTS----NG
LIS11_PENRW ECKCVRTIV-AHGHFISSLRWAPPLVKDAGAN------------EGANGTEAAS----NG
LIS1_SCLS1 EGKCVKTISDAHGHFVSCMRWAPSVIKDAPLLNGENG-------VGTPIKNGNG----AT
LIS1_PHANO EGRCVKVVTDAHSHFVSCMRWAPNVVKDAPTNGDAP--------NGTTANGASK------
LIS1_PYRTR EGRCVKTVTDAHGHFVSCMRWAPNVIKDVPVNGDAT--------NGAT-NGLSK------
LIS12_NEUCR EGRCVQTLTGVYEGFVSCIRWAPPVVKDADATAGNGR------SEGS-SLADPVVAARRR
LIS12_SORMK EGKCVQTLTGVYEGFVSCIRWAPPVVKDADAMAANTK------SGGTGPLADTVVAARRR
LIS12_PODAN DGKCVQTLSGMFDGFVSCVRWAPGITKD--GLAGGDA------GDGT-----------PK
LIS12_PENRW QGRCVKSISNAHDGFITCLKWVPGIAKDTRNGTMTISYQR----KGSAELPRSK------
LIS1_ASPTN EGRLVKTISNAHGHFISCIRWAPPPRNAAAEASETTNGVSK-------------------
LIS12_TALMQ EGKLVKTIDNAHSHFVTCMRWGP----SATTDVETTNGVTN-------------------
LIS1_EMENI EGRLVKTISGAHEHFVSCIRWAPSP--NTDNPDPAGEKAGK-------------------
LIS1_ASPNC GGRLVKTI-NAHGHFVSCIRWGPVPVSDVPVETSESTKSSK-------------------
LIS11_UNCRE EGKLVKTLEGAHEHFVSCIQWAPDPANLVQSSVAERPEGNKG------------------
LIS1_TUBMM DGRCVKTVDEAHSHFATCLRWAPAPAKEQTNGEAKTNGIPK-------------------
LIS1_PANTR K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_PIG K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_RAT K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_FELCA K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_MOUSE K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_PONAB K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_BOVIN K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_MACFA K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_HUMAN K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_CHICK K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_XENLA K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1_XENTR K-RCMKTL-NAHEHFVTSLDFHK-------------------------------------
LIS1B_SALSA K-RCMKTL-CAHEHFVTSLDMHQ-------------------------------------
LIS1_TETNG K-RCMKTL-CAHEHFVTSLDFHK-------------------------------------
LIS1B_DANRE K-RCMKTL-SAHEHFVTSLDFHK-------------------------------------
LIS1A_SALSA K-RCMKTL-GAHEHFVTSLDFHK-------------------------------------
LIS1A_DANRE K-RCTKTL-SAHEHFVTSLDFHK-------------------------------------
LIS1_BRAFL K-RCQKTL-EAHQHFCTSIDFHR-------------------------------------
LIS1_NEMVE K-RCAKTL-VAHEHFVTTLDFHK-------------------------------------
LIS1_IXOSC Q-RCCKTL-DAHSHFCTSLDFHR-------------------------------------
LIS1_DROGR K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROWI K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROVI K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROAN K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROPE K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROPS K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROMO K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROER K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROYA K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROME K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROSE K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_DROSI K-RCMKTL-YAHQHFCTSIDFHK-------------------------------------
LIS1_GLOMM K-RFMKTL-YAHQHFCTSVDFHK-------------------------------------
LIS1_AEDAE K-RCMKTL-YAHSHFCTSLDMHK-------------------------------------
LIS1_TRIAD K-RCSKSL-EAHNHFVTTIDFHR-------------------------------------
LIS1_CAEBR Q-RCMKAI-EAHEHFVSTVAFHQ-------------------------------------
LIS1_CAEEL Q-RCMKAI-EAHEHFVSTVAFHQ-------------------------------------
LIS1_SCHMA R-RCHKTL-NAHSHFVTSLDVNR-------------------------------------
LIS1_DICDI G-RCIKTINEAHTHFISCLDFCL-------------------------------------
LIS1_POLPP G-RCIKTINEAHSHFISCLDFCS-------------------------------------
LIS1_MONBE K-RVSKTI-PAHNHFVSCIAVHA-------------------------------------
LIS11_PARTE Q-KQKKKIENAHDKFILKCEINK-------------------------------------
LIS12_PARTE Q-KQKKKIENAHDKFILKCEINK-------------------------------------
LIS1_PHATC E-RCLRTLENAHNHFVSSLDMHA-------------------------------------
LIS11_POSPM G-RCMKVV-EAHSHFITCLAWGPPVQAGGDIKAASGSGNLRG------------------
LIS12_POSPM G-RCMXVV-EAHSHFITCLAWGPPVSAVARVELPR-TPFCGD------------------
LIS1_COPC7 G-RCLRIV-EAHSHFVAALAWGR--QAAGKSGSEKKVNGVDS------------------
LIS1_CRYNJ G-RCTKTI-EAHSHFVTSMTWGRAVGASGGIEKVN--GDASS------------------
LIS1_USTMA G-RCTRTI-EAHQHFATGIAWGKAKIEAPIPPAQD--GEEAG------------------
LIS1_YARLI GGRCIRVV-DAHGHFVTCVAWAPNDVN---------------------------------
LIS1_CANAW GYVNVVKTIIGHDGFINDIDFARLK--EASD----------------------------V
LIS1_CANAL GYVNVVKTIIGHDGFINDIDFARLK--EASD----------------------------V
LIS1_CANDC GSVNVVKTIIGHDGFINDIDFARLK--EASDS-------------------------TPT
LIS1_CANTT GSVTAIKTISGHEGFINDIDFARLTDSESNTD-------------------------KEL
LIS1_DEBHA GRVKCVKNLIGHEGFVNDIEFASFEITNNIHASKTADDGKT--------------KTEED
LIS1_PICST GSVKCVRTLSGHDGFINDLDFAAFNRDSGKEDKIKED------------------ATEEE
LIS1_PICGU GRVTEVKKLMKHEGFVNDINAAPLS------------------------------EPKDT
LIS1_EREGS TGQCLKVWPEASHGFINCLSVD--------------------------------------
LIS1_KLULA TTTCKKSWDLSNKGFQNCLTLD--------------------------------------
LIS1_LACTC TCEVVRSINNLHSGFINCIDID--------------------------------------
LIS1_YEAST TGQCLHVWEKLHTGFVNCLDLD--------------------------------------
LIS1_YEAS7 TGQCLHVWEKLHTGFVNCLDLD--------------------------------------
LIS1_YEAS8 TGQCLHVWEKLHTGFVNCLDLD--------------------------------------
LIS1_YEAS1 TGQCLHVWEKLHTGFVNCLDLD--------------------------------------
LIS1_YEAS2 TGQCLHVWEKLHTGFVNSLDLD--------------------------------------
LIS1_CANGA TGNCVKTWSSIHNNFINCIDIDREA-----------------------------------
LIS1_ZYGRC NGQCLKKWNRIHQGFVTCIDLD--------------------------------------
LIS1_KOMPG SNLLQPFRSISTQGFPSTLCMAKPVIKDQESDD---------------------------
*
LIS1_AJECG --------PDVQIRCVIATGSVDR---KLQIFAA--------
LIS1_AJECH --------PDVQIRCVIATGSVDR---KLQIFAA--------
LIS12_ASPCL --TFEESFSDVQIRCVVATGSVDK---KLQIFAG--------
LIS11_TALMQ ----KDNQPQVQIRCVVASGGVDQ---KLNIFAN--------
LIS1_TALSN ----KDNPPNVQIRCVVASAGVDC---KLNIYAN--------
LIS1_ASPFN -------PANIQMRCVVATGGWDQ---KLKIFAG--------
LIS1_ASPOR -------PANIQMRCVVATGGWDQ---KLKIFAG--------
LIS12_CHAGB ------APSEVQIRCLVATTSVDK---VVRIFAD--------
LIS1_ARTBC IKKSDSP--EVQIRCVIATGGVDM---KLRIFAN--------
LIS1_TRIVH IKKSDSP--EVQIRCVIATGGVDM---KLRIFAN--------
LIS1_ARTOC SKKTEGP--DVQIRCVIATGGVDM---KLRIFAN--------
LIS1_PYRO7 KKTEAAP--AVRIRCVIATGSVDM---KLRIFAN--------
LIS12_UNCRE GLKGDTP--DVQVRCVIATGGVDK---KLQVFAD--------
LIS1_GIBZE KAATAPQ--DVQIRCVIATGSVDM---SLRIFSR--------
LIS1_FUSV7 KAAAAPL--DVQIRCVIATGSVDT---SLRIFSR--------
LIS11_CHAGB AAGAGAA--EAQIRCVLATGSVDL---NVRIFAN--------
LIS11_PODAN AAGAAGAGGEAQIRCVIATGSVDL---NVRIFAN--------
LIS11_NEUCR GGAAATP--EAQIRCVIATGSVDL---NVRIFAN--------
LIS11_SORMK G-AAVTP--DSQIRCVIATGSVDL---NVRIFAN--------
LIS1_AJEDR KKEDPGGGAKLGIRCVIATGSVDL---NVRVFAS--------
LIS1_BLAGS KKEDPGGGAKLGIRCVIATGSVDL---NVRVFAS--------
LIS1_PARBP KKEDPGGGPMMGIRCVIATGSVDL---KVRVFAS--------
LIS1_PARBD KKEDPGGGPMMGIRCVIATGSVDL---KVRVFAS--------
LIS1_COCP7 KKEDTGGGGK--IRCVIATGSVDM---NVRVFAS--------
LIS1_ASPFU VRPDPNVATKISIRCVIATGSVDQ---KVRIFAT--------
LIS1_NEOFI VRPDPNAANKISIRCVIATGSVDR---KVRIFAT--------
LIS1_ASPFC VRPDPNVATKISIRCVIATGSVDQ---KVRIFAT--------
LIS11_ASPCL ARQDPNAANKISIRCVIATGSVDQ---KVRVFAT--------
LIS11_PENRW AKED---ATKMSIRCVLATGSVDL---KVRVFAA--------
LIS1_SCLS1 KKEDAKGSDIDCTSLMPQIPSI--------------------
LIS1_PHANO KKDEE--SAKAGIRCVIATGCVDL---NVRIFAS--------
LIS1_PYRTR KKEEE--AAKAGIRCVIATGCVDL---NVRIFAS--------
LIS12_NEUCR AATVGSVSASVQIRCVVATGSVDGAEGKVRIFAN--------
LIS12_SORMK AATVGSVNASVQIRCVVATGSVDGTEGKVRIFAN--------
LIS12_PODAN KKTGAEANGGVQMRCVVATGSVDGTEGKVRIFAN--------
LIS12_PENRW --LDEVGQPGVQIRCVLATGGEDQ---KIRVFALQANDRSHK
LIS1_ASPTN -----KAPTKPAFQCVIATGSADS---CVRVFK---------
LIS12_TALMQ -----KGTTKSKFQCVIATGSADS---CVRVFS---------
LIS1_EMENI -----KDAVKPSYRCVIATGCADN---SVRVFS---------
LIS1_ASPNC -----SDSVKPGFQCVIATGSADS---SVRIFT---------
LIS11_UNCRE -----TEHGTTGFRCVIATGSADS---CVRVFM---------
LIS1_TUBMM -----AGEKVINVRCVIATGSADM---NVRVFAS--------
LIS1_PANTR ------------TAPYVVTGFVDQ---TVKVWECR-------
LIS1_PIG ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_RAT ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_FELCA ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_MOUSE ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_PONAB ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_BOVIN ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_MACFA ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_HUMAN ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_CHICK ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_XENLA ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_XENTR ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1B_SALSA ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_TETNG ------------AAPYVVTGSVDQ---TVKVWECR-------
LIS1B_DANRE ------------ASPYVVTGSVDQ---TVKVWECR-------
LIS1A_SALSA ------------NAPYVVTGSVDQ---TVKVWECR-------
LIS1A_DANRE ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_BRAFL ------------SAPYVITGSVDQ---TVKVWECR-------
LIS1_NEMVE ------------SAPFVATGSVDL---TLKVWECR-------
LIS1_IXOSC ------------TAPYVVTGSVDQ---TVKVWECR-------
LIS1_DROGR ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROWI ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROVI ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROAN ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROPE ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROPS ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROMO ------------AHPYVISGSVDQ---SVKVWECR-------
LIS1_DROER ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROYA ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROME ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROSE ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_DROSI ------------AHPYVISGSVDQ---TVKVWECR-------
LIS1_GLOMM ------------KLPYVISGSVDN---TVKVWECR-------
LIS1_AEDAE ------------SHPYVISGSVDT---TVKVWECR-------
LIS1_TRIAD ------------SSPFVITGSVDL---TIKVWECR-------
LIS1_CAEBR ------------TNPYVITGSVDM---SCKVWECR-------
LIS1_CAEEL ------------TSPFVITGSVDM---SCKVWECR-------
LIS1_SCHMA ------------LAPYAITGSVDQ---TIHIWDCR-------
LIS1_DICDI ------------HNPHIATGGVDD---VIKVWKLQ-------
LIS1_POLPP ------------HNPHIATGGVDD---IIKIWKLG-------
LIS1_MONBE ------------KNTHVVTGSVDL---KVKVWECN-------
LIS11_PARTE ------------F--IFATCSVDQ---TIKLWLLS-------
LIS12_PARTE ------------F--IFATCSVDQ---TIKLWLLS-------
LIS1_PHATC ------------TLPILVSGSVDQ---TIRCWPLD-------
LIS11_POSPM -----TGADTERRMNVLATGSVDQ---TVCVWLP--------
LIS12_POSPM -----PKPIASRIMEEFNPRP---------------------
LIS1_COPC7 -----VDAEPEKVVNVVATGSVDE---TIKIWLP--------
LIS1_CRYNJ -----K---EPRRINVLATGSVDQ---TIKVWTP--------
LIS1_USTMA -----RKQPEARTVNVVATSSVDL---TIKIWTP--------
LIS1_YARLI ----------GRVRCLVATGGVDG---QVKVWQ---------
LIS1_CANAW SEEDLLKQVEKRMRCLFISGSADN---SIKLWN---------
LIS1_CANAL SEEDLLKQVEKRMRCLFISGSADN---SIKLWN---------
LIS1_CANDC SQEDLLKEVEKRMRCLFISGSADN---SIKLWN---------
LIS1_CANTT TSEEYLKDVEKRMRCLFISGSADN---SIKLWS---------
LIS1_DEBHA RRNELMKSIESKIRCLFISGGVDN---CIRLWS---------
LIS1_PICST SHQQLMKFIEGRMRCLFISGAADN---SIKLWS---------
LIS1_PICGU TNEDILQDIESRMRCVFVSGGTDN---TVRLWS---------
LIS1_EREGS ----SDVSNDKLLRELFLSGSIDG---KCNVFMR--------
LIS1_KLULA ----NIAFTGLPSRKLLFSGSSEG---TLTSFMR--------
LIS1_LACTC ----CGGLN----RQLLVSGGADG---KLVILMK--------
LIS1_YEAST ----VDFDSNVTPRQMMVTGGLDC---KSNVFMR--------
LIS1_YEAS7 ----VDFDSNVTPRQMMVTGGLDC---KSNVFMR--------
LIS1_YEAS8 ----VDFDSNVTPRQMMVTGGLDC---KSNVFMR--------
LIS1_YEAS1 ----VDFDSNVTPRQMMVTGGLDC---KSNVFMR--------
LIS1_YEAS2 ----VDFDSNVTPRQMMVTGGLDC---KSNVFMR--------
LIS1_CANGA ---TIEQFSPSLQREILVSGDMDN---KVKIIR---------
LIS1_ZYGRC ------DSNHPLKRKIMVTGGIDC---KCHIFMQ--------
LIS1_KOMPG -----LILLNEAMRCYLAVGHSDG---TVTLWKKNIQKEYIL