CLUSTAL format seed alignment for MF_03143
_____________________________________________________________________________
Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
D0NXA2_PHYIT ------MSGSPQVVPCGS---------------------YDIVLGSSLLQSRFVAEDLLQ
H3GHV1_PHYRM -------MSAPQVVSCGS---------------------YDIVLGSSLLQSRFVAEDLLQ
A9V1N3_MONBE -------MEKATVVPCTG---------------------YNVVVGYEFW--RQLPLDLIK
ARO1_EMENI -------MSNPTKISILG---------------------RESIIADFGLWRNYVAKDLIS
ARO1_ASPFU -------MTGPTKISILG---------------------QESIVADFGLWRNYVAKDLIS
ARO1_AJECG -------MGVPTKISILG---------------------RESIVADFGIWRNYVAKDLLS
ARO1_PHANO -MATNGVKAEPTKVNILG---------------------KDSIVVDYGLWQSYIAEDLLQ
ARO1_FUSV7 --MAEAKKPGPERISILG---------------------EANIIVDHGLWLNFVVDDLLQ
I1RK93_GIBZE --MAQASGQDPTRISILG---------------------EPNIIVNHGLWLNFVVDDLLQ
ARO1_NEUCR --MAEPI-SNPTRINILG---------------------KDNIIIDHGIWLNFVAQDLLQ
ARO1_SCLS1 --MGSTTFENPTRIEILG---------------------KEDIIVDFDIWRNFVAEDLLS
D5G8D9_TUBMM --MSGDNGSTVTTVQILR---------------------KDTIKVGYDL-TDTITVDLLQ
ARO1_SCHPO ----MSNESNIITVPILG---------------------KDTVRVGFGI-HQYICTEILE
ARO1_PNECA -------MKEIIKLSILG---------------------KDSIHIGLHL-WPHITNELFT
ARO1_CANAL --------MSIEKVPILG---------------------KETIHVGYGI-ADHIVREVIA
ARO1_YEAST -------MVQLAKVPILG---------------------NDIIHVGYNI-HDHLVETIIK
ARO1_YARLI ----MFAEGQIQKVPILG---------------------KESIHIGYKM-QDHIVSEIVA
ARO1_COPC7 MAVADDTKADLLKVSILG---------------------KESIHCGFHL-TPYIVQTVLT
ARO1_CRYNJ ---MSSSSADVLKISILG---------------------NESIHVGFHL-LPYIFKTITT
ARO1_USTMA MTSTASAQQPVLRTKTPSYHAPPSTDPLSGATIHTLRCLDTPIHLGYHL-IPHIAKTLLS
E3KTD2_PUCGT ---MAHSVCDVQTVSILG---------------------KPSIRLGYHL-APYIAHTVLT
F4PAP8_BATDJ ----------MHKVSILG---------------------TESIVVGKGI-VGHIAADVVS
I1CAL1_RHIO9 ---MATVNPDVVKVSILG---------------------SESIIAGFHL-TEYLLRDVLT
I7MKQ2_TETTS ------MKQEALQVESIS---------------------NGDYHLVFPKELNMIPTLIRQ
: :
D0NXA2_PHYIT RLPTTSTFVILTDANVGPL------YAEPLRAQLAELLQIQGNAARRVLLHAVPAGEASK
H3GHV1_PHYRM RLPSTATFVILTDANVGPL------YAEPLRVQLAALLHAQGNTTRRVLLHAIPSGEASK
A9V1N3_MONBE YVPA-SKYIIITDLNVQQH------YGDELLRALNEALP----DGIEALLYAVAPGEASK
ARO1_EMENI DCSS-TTYVLVTDTNIGSI------YTPSFEEAFRKAAAEITPS-PRLLIYNAPPGEVSK
ARO1_ASPFU GCPS-TTYVLITDTNIGSI------YTPGFQKSFEEAAASVSPS-PRLLIYNAPPGEVSK
ARO1_AJECG SCSS-STYILISDTNLTPL------YLEGFQRSFEDAATNVSPK-PRLLTYEIPPGESSK
ARO1_PHANO NIPS-STYVLITDTNIGPT------YTPTFERSFSAAAASIASS-PRLLTYTIPPGETSK
ARO1_FUSV7 NTPT-STYVLITDTNLFDT------YVPAFQAQFEAAAEG--KA-TRLLTYTIPPGEASK
I1RK93_GIBZE NIAT-STYVLITDTNLFNS------YVPAFQSRFEHASQG--KD-TRLLTYTIPPGEASK
ARO1_NEUCR NIKS-STYILITDTNLYKT------YVPPFQSVFEKAAP---QD-VRLLTYAIPPGEYSK
ARO1_SCLS1 DLPS-STYVLITDTNLSPL------YVPAFQQSFEALAAKSSST-PRLLTYEIPPGENSK
D5G8D9_TUBMM NLIS-STYVLITDTNLAPL------YLPAFESSFNKNALKYSPE-ARLLSYIIPPGEYSK
ARO1_SCHPO NFKS-STYVVITDSNIAPL------YLEKIESTFNKSIKDAKAE-ARLLTYVIPPGESSK
ARO1_PNECA CIFS-PTYVIITDSNIETL------YIPSFKTYFISMAKQRSIN-SRLLFFTIPPGEKSK
ARO1_CANAL NLAS-STYVIVTDTNMARTP-----QYSKLTDDFKTNLSEKRPE-SRLLTYCVSPGENNK
ARO1_YEAST HCPS-STYVICNDTNLSKVP-----YYQQLVLEFKASLPE---G-SRLLTYVVKPGETSK
ARO1_YARLI NIKS-STYILVTDTNIEDLG-----YVESLKTKFEAAFAKDGIK-SRLLTYTVAPGETSK
ARO1_COPC7 TLPS-STYVLITDDNIAKLH--LNKFEEAFAKGIEKSAANPKP---RFLSHVIPPGETSK
ARO1_CRYNJ TLPS-STYVLITDTNLSAIY--LNDFKASFEEA--ASEADNKA---RFLVYEVAPGEGAK
ARO1_USTMA TLPS-STYVLITDQNLEARCSVTTAFRREFEKAAVHLSSSHSW---RLLTKVIPPGEASK
E3KTD2_PUCGT ELHS-STYVLITDSNVSPRH--VPALKAAFENQ-----LPKSA---RLLTYILPPGEQSK
F4PAP8_BATDJ CIPA-STYAIITDENLAKLH--LDELLAAFQREIANQTAATASK-SRILSVVIPAGEVHK
I1CAL1_RHIO9 NIPA-SNYVLITDSHLASIY--LEKYAGAFQSVSEELYKSKGIKEPRFFTRVLPPGEMTK
I7MKQ2_TETTS KFSKLSKLMLVMDSNINRIYG------SNMISFFQKSQD------VEVYTFVIQQGETQK
.. : * :: : . ** *
D0NXA2_PHYIT CREMKAKIEDEVLF-PKRCHRDTCVVAVGGGVVGDLAGYVASTYMRGVPFVQVPTSLLAC
H3GHV1_PHYRM CREMKAKIEDEVLF-PNRCHRDTCIVAVGGGVVGDLSGYVASTYMRGVPFVQVPTSLLAC
A9V1N3_MONBE SRETKRALEDWML--ARGFDRKSCIVALGGGVVGDLAGFVAATFMRGINFVQVPTTLLAM
ARO1_EMENI SRQTKADIEDWMLSQNPPCGRDTVVIALGGGVIGDLTGFVASTYMRGVRYVQVPTTLLAM
ARO1_ASPFU SRQTKADIEDWMLSQSPPCGRDTVVIALGGGVIGDLTGFVAATYMRGVRFVQVPTTLLAM
ARO1_AJECG SRETKADIEDWMLARQPPCGRDTVIIALGGGVIGDLIGFVAATYMRGVRFVQVPTTLLAM
ARO1_PHANO SRSTKAAVEDWLLSQG--CTRDTVIIALGGGVIGDMIGYVAATYMRGIKFVNVPTTLLAM
ARO1_FUSV7 SRETKAEIEDWMLSQQ--CTRDTVIIALGGGVMGDMIGYVAATFMRGVRFVQVPTTLLAM
I1RK93_GIBZE SRDTKAEIEDWMLSQQ--CTRDTVIIALGGGVMGDMIGYVAATFMRGVRFVQVPTTLLAM
ARO1_NEUCR GRDTKAEIEDWMLSHQ--CTRDTVIIALGGGVIGDMIGYVAATFMRGVRFVQCPTTLLAM
ARO1_SCLS1 SRETKAEIEDWMLSHQ--CTRDSVIIALGGGVIGDMIGYVAATFMRGVRFVQVPTTLLAM
D5G8D9_TUBMM SRSTKAEVEDWMLSEK--CTRDTVVIALGGGVIGDMIGYVAATFMRGVRFIQVPTTLLAM
ARO1_SCHPO CRAMKAEIEDWLLTQS--CTRDTILIAMGGGVIGDLVGYVAASFMRGIRFIQMPTTLLAM
ARO1_PNECA SRKTKALIEDWLLSEK--CTRDTVIIAIGGGVIGDLVGYVSATFMRGVRFIQIPTTLLAM
ARO1_CANAL NRATKAAVEDFLLQQG--CTRDTVILAVGGGVIGDMIGFVAATFMRGVRVVQVPTTLLAM
ARO1_YEAST SRETKAQLEDYLLVEG--CTRDTVMVAIGGGVIGDMIGFVASTFMRGVRVVQVPTSLLAM
ARO1_YARLI SRATKAAIEDWMLSKG--CTRDTVILAVGGGVIGDMIGYVAATFMRGVRFVQIPTTLLAM
ARO1_COPC7 SREGKARIEDFLLFHK--CTRDSVILALGGGVIGDLVGFVAATFMRGVRFCQIPTTLLAM
ARO1_CRYNJ SRKVKGEIEDWMLDNK--CTRDTVILAFGGGVIGDLTGFVAATFMRGVKFVQIPTTLLAM
ARO1_USTMA SRDGKNAIEDWMFEHR--VTRDAVVLAVGGGVIGDLVGFVAATFMRGLKFVQIPTTLLAM
E3KTD2_PUCGT SREMKAVLEDWLLDHR--CTRDTVVLALGGGVIGDLIGFVSATFMRGIRFCQIPTTLLAM
F4PAP8_BATDJ TRDTKASIEDWLLSQA--CTRDSCLIALGGGVLGDLVGFVAATFMRGVPVVQIPTTLLAM
I1CAL1_RHIO9 SRKVKADIEDWLLSNA--VTRDTCFLAMGGGVIGDLVGYVAATFMRGVPFVQIPTTLLAM
I7MKQ2_TETTS NMENISSLMDSLFKHK--FNRTDVLVGFGGGLITDFAGFAASIYKRGMKYVSIPTTVLAM
: * :: * .:..***:: *: *:.:: : **: . **::**
D0NXA2_PHYIT VDSSIGGKTGIDVEAGKNLLGAFHMPQRVYIDLNVLHTLPKRELINGMGEVIKSGAIFDA
H3GHV1_PHYRM VDSSIGGKTGIDVEAGKNLLGAFHMPQRVYIDLSVLHTLPKRELINGMGEVVKSGAIFNA
A9V1N3_MONBE VDSSIGGKTGIDTPAGKNLVGAFHRPKRVYADLAFLSTLPEREFNNGMAEVIKAGAIYDA
ARO1_EMENI VDSSIGGKTAIDTPLGKNLIGAIWQPTKIYIDLEFLETLPVREFINGMAEVIKTAAISSE
ARO1_ASPFU VDSSIGGKTAIDTPLGKNLIGAIWQPSRIYIDLEFLETLPVREFINGMAEVIKTAAISSE
ARO1_AJECG VDSSIGGKTAIDTPNGKNLIGAIWQPQRIYLDMEFLNTLPEREFINGMAEVIKTAAISSD
ARO1_PHANO VDSSIGGKTAIDVPAGKNLVGAFWQPERIYIDLQFLETLPKREVINGMAEVVKTAAIWNE
ARO1_FUSV7 VDSSIGGKTAIDTPMGKNLVGAFWQPKRIYIDLAFLETLPVREFINGMAEVVKTAAIWNE
I1RK93_GIBZE VDSSIGGKTAIDTPMGKNLVGAFWQPKRIYIDLTFLETLPVREFINGMAEVIKTAAIWNE
ARO1_NEUCR VDSSIGGKTAIDVPMGKNLIGAFWQPERIYIDLTFLNTLPVREFINGMAEVIKTAAIWDE
ARO1_SCLS1 VDSSIGGKTAIDTPLGKNLVGAFWQPQRIYIDLRFLETLPVREFINGMAEVVKTAAIWDE
D5G8D9_TUBMM VDSSIGGKMAIDSPHGKNLIGAFWQPERIFIDMKFLETLPEREFVNGMAEVVKTAAIWDE
ARO1_SCHPO VDSSIGGKTGIDTPLGKNLVGAFWQPLRVYVDMVFLHTLPPRQVINGLSEIIKTAAMWNE
ARO1_PNECA VDSSIGGKNSINTSYGKNAIGTIWQPERIFIDFTFLETLTEKEFINGIAELIKTIIIWDE
ARO1_CANAL VDSSVGGKTAIDTPLGKNFIGAFHQPEYVFCDVSFLETLPARQFINGMAEVVKTAAIWNE
ARO1_YEAST VDSSIGGKTAIDTPLGKNFIGAFWQPKFVLVDIKWLETLAKREFINGMAEVIKTACIWNA
ARO1_YARLI VDSSIGGKTAIDTPLGKNLVGAFWQPVNIFIDTSFLETLPVREFINGMAEVIKTAAFYDA
ARO1_COPC7 VDSSVGGKTAIDTPHGKNLIGAFWQPEYIFIDAAYLETLPTREFSNGMAEVVKTAAIWDE
ARO1_CRYNJ VDSSVGGKTAIDTPHGKNLIGAFWQPSYIFVDLAFLTTLPTREVSNGMAEVIKTAAIWKD
ARO1_USTMA VDSAVGGKTAIDHPLGKNLIGSFHQPNYVFIDAAWLKTLPVREFSNGMAEVVKTAAIWDP
E3KTD2_PUCGT VDSSVGGKTAIDTPLGKNLVGAFWQPSFIFIDASYLETLPEREFVNGMAEMIKTAAIWDE
F4PAP8_BATDJ VDSSVGGKTAVDTPNGKNLIGAFHQPRRIFIDIQYLTTLNKREFVNGLAEVIKTAAIWDE
I1CAL1_RHIO9 VDSSIGGKTAIDVPAGKNLIGAFWQPKRIFIDVNFLTTLPEREFSNGMAELIKTAAISNE
I7MKQ2_TETTS SDAAIGSKTGVNNQYGKNMVGSFYDPELIIVCEKFLESLDDRNMSNGIAEIIKIAAMIDL
*:::*.* .:: *** :*:: * : * :* ::. **:.*::* : .
D0NXA2_PHYIT ELFELLENSAETILSLS--------------------------DMDIVQRVVALTVQVKA
H3GHV1_PHYRM ELFELLETSAESILALS--------------------------DMDLVQRVVALTVQVKA
A9V1N3_MONBE ALFQLLELQSEQIRAL---------------------------DPDLLTQMVLAAVRVKV
ARO1_EMENI EEFTALEENAETILKAVRREVRPGE-------------HRFEGIEEILKARILASARHKA
ARO1_ASPFU EEFTALEDNAETILSAVRREVKPGQ-------------RRFEGIEEILKARILASARHKA
ARO1_AJECG EKFAALERDAETILAAVKSKNTPER-------------PRFSGIEETLKRTILSSAEFKA
ARO1_PHANO EEFTALEGNADAILAAMDQKTTDGR-------------RNFDSIAGILKRIVLGSVRVKA
ARO1_FUSV7 TEFTVLEESAAHILECVRSKGE----------------GRLTPIKDVLKRIVIGSAGVKA
I1RK93_GIBZE TEFSVLEESAAHILECVRSKGE----------------GRLTPIKDVLKRIVIGSAGVKA
ARO1_NEUCR NEFTALEENAKAILEAVRSKNKS-A-------------DRLAPIRDILKRIVLGSARVKA
ARO1_SCLS1 AEFSALEDNANLIMTTIRAKNTDCS-------------TRLGPIRDILKRIVLGSAKTKA
D5G8D9_TUBMM AEFARLEQSSGLILETVRAKSSG-----------------------------NKAQIGNA
ARO1_SCHPO NDFQLLENNSAVLLDALNKPSVPGE-------------YKFDSIKPLLQKIILSSIRTKC
ARO1_PNECA SEFASLENISEKIAKTVRSMSLTSNK-----------HSKFNEIIKDLKRYIISSIKIKA
ARO1_CANAL EEFTRLENFSKKFLSVVTSKK-----------------PDLQSIKAELVKTVLESVRVKA
ARO1_YEAST DEFTRLESNASLFLNVVNGAKNVKVTNQLTNEIDEISNTDIEAMLDHTYKLVLESIKVKA
ARO1_YARLI EEFTRLESASEIFLSTIKKRD-----------AKDPRRVDLSPITDTIGRIVLGSARIKA
ARO1_COPC7 KEFTSLESRSAELFAAIQTP--STNY-------AGRTLETRSEAQKLLLSTIAASIGVKA
ARO1_CRYNJ DDFALLESRSAEISLAASSR--PTGVP-----TAGRFVSDRSHAQSLLLQVVSGSIYVKA
ARO1_USTMA IDFAKLESSAPAIRSAVLGPFAKDAPL-----DQGRTLETRTESQSLLLDVIRGSVGVKA
E3KTD2_PUCGT SQFENWNP-------------------------------TRSQAQKLLLQVIADSVGVKS
F4PAP8_BATDJ KDFQMLENHSDRILGLVGSD-------------SNQGECIAVILMDLVTRLILGSIKVKA
I1CAL1_RHIO9 EDFNKLENGVEAIRHAVLGNDSKDPNQ-------GATLETRTASQSLLLDVILASARFKA
I7MKQ2_TETTS DLFVLLELNDVKSLRDN---------------------------PSILRQIIRRSMELKI
* : : :
D0NXA2_PHYIT TVVTQDTKEMGLRAILNFGHSIGHGIEALLQPEYLHGECVSMGCIKEAEIARGMGICTSA
H3GHV1_PHYRM TVVTQDTKEMGLRAILNFGHSIGHGIEALVQPEYLHGECVSMGCIKEAEIARGMGVCSSA
A9V1N3_MONBE TVVLQDEKEAGLRAILNFGHSIGHGIEALLTGHWLHGECVAVGMIKETEVARARGILSPD
ARO1_EMENI YVVSADEREGGLRNLLNWGHSIGHAIEAILTPQILHGECVAIGMVKEAELARHLGILKGV
ARO1_ASPFU FVVSADEREGGLRNLLNWGHSIGHAIEAILTPQILHGECVAIGMVKEAELARHLGILKGV
ARO1_AJECG QVVSADEREGGLRNLLNFGHSIGHAIEAILAPQVLHGECVSIGMVKEAELARHLGILNNV
ARO1_PHANO EVVSADEREGGLRNLLNFGHSIGHAYEAILTPQILHGECVAIGMVKEAELARYLGVLDPS
ARO1_FUSV7 EVVSSDEREGGLRNLLNFGHSIGHAIEAILTPQLLHGEAVAIGMVKEAELARYLGVLRPG
I1RK93_GIBZE EVVSSDEREGGLRNLLNFGHSIGHAFEAILTPQLLHGEAVAIGMVKEAELARFLGVLRPG
ARO1_NEUCR EVVSSDEREGGLRNLLNFGHSIGHAYEAILTPQVLHGEAVAIGMVKEAELARFLGVLRPS
ARO1_SCLS1 DVVSADEREGGLRNILNFGHSIGHAFEAILTPQVLHGEAVAIGMVKEAELARHLGVLKPG
D5G8D9_TUBMM HVVSADEREGGLRNLLNFGHSIGHAIEAILFPQMLHGECVAIGMVKEAELARHLGVCKPG
ARO1_SCHPO EVVTLDEHEGGLRNLLNFGHSIGHAYEAILYPQILHGECVAIGMVKEAELARYLGILKPN
ARO1_PNECA HIVSIDEKEKDLRTLLNFGHSIGHAIETVLAPYILHGESISIGMVKEAELSRHLGILNPN
ARO1_CANAL GVVSSDEKEAGLRNLLNFGHTIGHAIEAVLTPEALHGECVSIGMIKEAELSRYLGILPPV
ARO1_YEAST EVVSSDERESSLRNLLNFGHSIGHAYEAILTPQALHGECVSIGMVKEAELSRYFGILSPT
ARO1_YARLI AVVSADEREGGLRNLLNFGHSIGHAYEAILTPYILHGECVAIGMVKEAELSRYLGILSPV
ARO1_COPC7 HIVTIDERETGLRNLVNFGHSIGHAIEAVLTPTILHGECVSIGMILEAELSRQLGILTQV
ARO1_CRYNJ HIVTIDERETGLRNLVNFGHTIGHAIEAVLTPAMLHGECVSVGIVLEAEVARQLGILSQV
ARO1_USTMA HIVTIDEKETGLRNLVNFGHTIGHAIEAVLTPEMLHGECISIGMILEAEVARYMHGLSQV
E3KTD2_PUCGT EVVTKDEKETGLRNLVNFGHTIGHAIEAVLTPAILHGECVSIGMILEAEVARARGCLSSS
F4PAP8_BATDJ HVVTVDEKETGLRGLLNFGHTIGHAIEAIAFPHLLHGECVAIGMVKEAEVSRFLGHLNNV
I1CAL1_RHIO9 YVVTNDEREGGLRGLLNFGHSIGHGIEAIVSPMMLHGECVSIGCMKEAELARNLGHLNQV
I7MKQ2_TETTS SIVSQDKFESDKRMILNYGHTIGHGIETASKEALLHGECVSIGIILENEIALHRYQTSFK
:* * * . * ::*:**:***. *: ****.:::* : * *::
D0NXA2_PHYIT TVGRLRRCLAAYGLPVRVPD------------HVATRDVLVKMEVDKKN-SQGVKKIVLL
H3GHV1_PHYRM TVGRLRRCLASYGLPVRVPE------------HVATRDVLVKMEVDKKN-SQGVKKIVLL
A9V1N3_MONBE ALNRLLSCCQAYHLPTTIPT------------GVSHNDVLHKMAVDKKN-ERGRKHIVFL
ARO1_EMENI AVSRIVKCLAAYGLPTSLKDARIRKLTAGK--HCSVDQLMFNMALDKKN-DGPKKKIVLL
ARO1_ASPFU AVARIVKCIAAYGLPTSLKDSRIRKLTAGK--HCSVDQILFNMALDKKN-DGPKKKIVLL
ARO1_AJECG SVSRISKCLASYGLPTSLKDQRIKKLTAGK--HCSVEQLIAYMGVDKKN-DGPKKKVVLL
ARO1_PHANO AVARLTKCIASYGLPTSLADKTVRRRSANK--HCPVDELIKIMAVDKKN-AGAVKKIVLL
ARO1_FUSV7 AVARLVKCIASYDLPTSIHDKRVVKLTAGK--KCPVDVLLQKMGVDKKN-DGQKKKIVLL
I1RK93_GIBZE AVARLVKCIASYDLPTSLQDKRVTKLTAGK--KCPVDVLLEKMGVDKKN-DGKKKKIVLL
ARO1_NEUCR AVARLSKCIASYDLPTSLQDKRIVKLTAGK--ECPVDVLLQKMAVDKKN-EGRKKKIVLL
ARO1_SCLS1 AVARLVKCIASYGLPTSLADKRIQKLTAGK--LCPVDVLLEKMGVDKKN-DGRKKKIVLL
D5G8D9_TUBMM AVARLSKCLTSYGLPTSLEDKRVKKLTAGK--HCGVERMLSIMGVDKKN-DGRKKKVVLL
ARO1_SCHPO AVGRLTKCLVSYNLPISVNDPKVKKYASFK--HCPVEKLIEYMAVDKKN-QGSKKRIVIL
ARO1_PNECA VVSRLIKCLNTWGLPTSFKDRRFKEVILGK--KHLIEDILEIMSIDKKN-DSNNKKIVLL
ARO1_CANAL AVARLSKCLVAYGLPVSIDDKEFLKKVGPKRHYVEIDILLKKMAIDKKN-DGSKIRCVLL
ARO1_YEAST QVARLSKILVAYGLPVSPDEKWFKELTLHK--KTPLDILLKKMSIDKKN-EGSKKKVVIL
ARO1_YARLI AVARLAKCIKAYELPVSLDDATVKARSHGK--KCPVDDLLRIMGVDKKN-DGSTKKIVIL
ARO1_COPC7 GVGRLTRCLKAYNLPTSLSAPLIASLPQAS--LLTVPRLLDIMRIDKKN-SGTNKKIVLL
ARO1_CRYNJ AVGRLTRCLQAYGLPVSLSDRRITALPASS--QLSVDRLLDIMKIDKKN-SGPAKKIVLL
ARO1_USTMA AIGRLTRCLKEYDLPVSLSDSRVTRLAKSL--DVTVDRLLDIMKVDKKN-SGTNKKIVLL
E3KTD2_PUCGT AIARLSKCLKAHGLPVSLTDPRILSSPNAP--NLNLDRLLDLMSVDKKN-EGKIKKIVLL
F4PAP8_BATDJ SVGRLVRCLRAYGLPVSLNDPLVSTRCPNK--TFPTHRLLDIMRVDKKN-QGDKKRIVLL
I1CAL1_RHIO9 AVGRLARCFSSYGLPISLDEKKVKDRIGNL--YCHVDDIMEIMKVDKKN-QGDKKRIVML
I7MKQ2_TETTS FTKRVEKLLLQYNLPVEVPK------------FIKNEDVLFYMGNDKKNSNSHTFQIVFV
*: ** :: * **** : *::
D0NXA2_PHYIT EEIGKVLANPYARAVKDNQIELVLEKQVRMLPGAKANGT--------IRVPGSKSISNRV
H3GHV1_PHYRM EKIGKVLADPYARAVKDHQIELVLEKQVRMVPGAKANGT--------IRVPGSKSISNRV
A9V1N3_MONBE RAIGD--AGQGAEPVEDDLLLRIMAPAVEVVPHGPIAGT--------IRVPGSKSISNRV
ARO1_EMENI SAIGTP-YETRASVVANEDIRVVLAPSIEVHPGVAQSSN------VICAPPGSKSISNRA
ARO1_ASPFU SAIGRT-YEPRASVVPNEDIGVVLAPSIEVHPGVSTTSE------VVCAPPGSKSISNRA
ARO1_AJECG SAIGRT-HEPRASTVSNEEIQIVLAPSIEVSPGVPKGLD------VTCTPPGSKSISNRA
ARO1_PHANO SGIGRT-YEKKASSVVDRDIKIALSPSISVHPGIPSDLN------VTCTPPGSKSVSNRV
ARO1_FUSV7 SAIGKC-HEPRASVVDDKTIRTILSPSIQVTPGVPSNLD------VTVTPPGSKSISNRA
I1RK93_GIBZE SAIGKC-HEPRASVVDDKTIRTILSSSVQVTPGVPKDLA------VTVAPPGSKSISNRA
ARO1_NEUCR SAIGKT-YEPKASVVEDRAIRIVLSPCIRVFAGVPKDLN------VSVTPPGSKSISNRA
ARO1_SCLS1 SAIGKT-YEPKASVVEDRSIRVVLSDSVEVRPSVPETLN------VEVTPPGSKSISNRA
D5G8D9_TUBMM AAIGRT-YEKKASVVDDDSIRVILSPSVIVHSQRSGVPE------LEVTPPGSKSISNRA
ARO1_SCHPO KAIGET-YEKHATVVSDDDIRFILSRDVKVDEFTKSSWD------VVVTPPGSKSISNRA
ARO1_PNECA SAIGKT-YEKKASSVSDDDIRTILSQNILLYGIPLNAFQKH----TTITLPGSKSISNRA
ARO1_CANAL EKIGKC-YQLKAHQVSKQDLSFVLTDEVLVHPFTNPPKE------NIIVPPGSKSISNRA
ARO1_YEAST ESIGKC-YGDSAQFVSDEDLRFILTDETLVYPFKDIPADQQ----KVVIPPGSKSISNRA
ARO1_YARLI SAIGKT-HEQKASSVADKDIRFVLSEEVIVGEAPVGDKKS-----YTVTPPGSKSISNRA
ARO1_COPC7 KRIGET-YEQKASIVEDKAIEKTLAEAVTVVPSIPTGNVKGSPGEVRMSTPGSKSISNRA
ARO1_CRYNJ SRIGKT-YEEKASVVADDVISKVLCEAVTVKAATPTKSP------ITMATPGSKSISNRA
ARO1_USTMA SSIGDT-VQNMASTVSDHIIRRVLSLAATVTPIHEQPNKP----KVTLSTPGSKSISNRA
E3KTD2_PUCGT SRIGKT-FEERATGVEDSLIRRVLAPAVRVHPGPPPANIK----EVTLRTPGSKSISNRA
F4PAP8_BATDJ SALGAT-VEPRASFVADDVIQKIISPAVLVTPSNTKLNVS-------LAIPGSKSISNRA
I1CAL1_RHIO9 SSIGKT-LEPRASVIADADIHKVLAPEQLVLPVTESATGPKK--EVSLTTPGSKSISNRA
I7MKQ2_TETTS EDVGKV--IYKTAAVSGQEVLNVLSPSVKIGASDFSKISDN----IVIQLAGSKSITNRV
:* : : : : : .****::**.
D0NXA2_PHYIT LLMAALGEGSCRITGLLHSDDTQVMMNALQK-VGAKFSWEDNGAVLVVEGTAGKFATVAD
H3GHV1_PHYRM LLMAALGKGACRITGLLHSDDTQVMMTALQK-VGAKFSWEDNGAVLVVEGTAGKFATVAD
A9V1N3_MONBE LLMAALGRGVCRLRGLLHSDDTKVMIAALRK-LGVRIEFEDNGHVLLIQGCDGKLQAAGD
ARO1_EMENI LVLAALGSGTCRIKNLLHSDDTEVMLNALERLGAATFSWEEEGEVLVVNGKGGN--LQAS
ARO1_ASPFU LVLAALGSGTVRIKNLLHSDDTEVMLNALERLGAATFSWEEEGEVLVVNGKGGA--LQAH
ARO1_AJECG LVLAALGSGTCRLKNLLHSDDTEVMLNALERLGAATFSWEDEGEVLVVSGKGGR--MEAS
ARO1_PHANO LVLAALGTGSCRITNLLHSDDTQVMLDALAKMQGASFSWENDGKELVVTGNGGQ--LKAS
ARO1_FUSV7 LVLAALGLGSCRIKNLLHSDDTEYMLSAIHQLGGASYSWQDAGEVLVVDGKGGN--LQAS
I1RK93_GIBZE LVLAALGSGTCRIKNLLHSDDTQYMLSAIHQLGGASYSWQDAGEVLVVEGKGGN--LQAS
ARO1_NEUCR LILAALGEGTTRIHNLLHSDDTQVMLNAVAQLQGASFSWEE-GDVLVVKGNGGK--LQAT
ARO1_SCLS1 LVLAALGTGPCRIKNLLHSDDVEFMLTSIGKLGGATYAWEDAGEVLCVQGKGGD--LHAS
D5G8D9_TUBMM LVLAALGSGTCHVKNLLHSDDTEHMLTALHNLGGIQYSWEEDGDVLVVNGNGGK--LRAC
ARO1_SCHPO LVLAAMGNGTCRLTNMLHSDDTQFMMSALESLGAATFSWEDGGETLVVKGNGGK--LAVP
ARO1_PNECA LILASLSNGICYLKNFLHSDDTYYMLSALEKLNAAEFKWEQDGDVLVVKGKSGY--LENP
ARO1_CANAL LILAALGNGTVRVKNLLHSDDTKHMLDAVASLKGAEISTEDNGETIVVKGNGGN--LVTS
ARO1_YEAST LILAALGEGQCKIKNLLHSDDTKHMLTAVHELKGATISWEDNGETVVVEGHGGST-LSAC
ARO1_YARLI FVLTALGKGPCKLRNLLHSDDTQHMLEAIELLGGASFEWEADGETLLVTGNGGK--LTAP
ARO1_COPC7 LVLAALAKGTCRLRNLLHSDDT----------QGAVFTWEDGGETLVVEGGEGTLTVPTP
ARO1_CRYNJ LVLAALGKGTCRVRNLLHSDDTAVMMNALVELKGAVFSWEDGGDTIVVEGGGGILSTPAK
ARO1_USTMA LVLAALATNTCRLRNMLHSDDTQVMMAGLHDLQAARFEFEDGGETIVVHGNAGALARPAN
E3KTD2_PUCGT LILAALGHGTCRLKNLLHSDDTQVMINALEEMKGASFSWEDNGATLVVSGGAGKLSSPAN
F4PAP8_BATDJ LVMAALGKGVCRLHGLLHSDDVQVMLDALQKLVGISYTWENKGETLVVNGGGGKLRSPQS
I1CAL1_RHIO9 LLIAALGSGTVRIKNLLHSDDTQFMLAALKSLNAADFEWEDNGETLVVHGGNGR--LVVP
I7MKQ2_TETTS LILSALLDKEIQLQNVLFAEDTEVMMKSLQTLGACSIQQLDANTVKVKGNGGAFN--FQD
:::::: : ..*.::*. . . . .
D0NXA2_PHYIT GEEIYLSNAGTAARFLTSAMTLVPSEN------DGTVVVTGNYRMKERPIASLVDALRGN
H3GHV1_PHYRM GEEIYLSNAGTAARFLTSAMTLVPSEN------DGTVVVTGNYRMKERPIAPLVEALRGN
A9V1N3_MONBE -NALFLANAGTASRFLTSACCLASS---------GHSLVTGVKRMHERPIGDLVEALRAV
ARO1_EMENI SSPLYLGNAGTASRFLTTVATLANSST------VDSSVLTGNNRMKQRPIGDLVDALTAN
ARO1_ASPFU PSPLYLGNAGTASRFLTTVATLATASS------VDSSVLTGNNRMKQRPIGDLVDALTAN
ARO1_AJECG PSELYLGNAGTASRFLTTVATLARKSS------VDSSVLTGNARMKQRPIGDLVDALAAN
ARO1_PHANO SNELYLGNAGTAARFLTSVTALCQAQE-----GVTSTVVTGNARMKERPIGPLVKSLRTM
ARO1_FUSV7 KEALYLGNAGTASRFLTTVVALCSPSE-----SASSTILTGNARMKVRPIGPLVDALRSN
I1RK93_GIBZE KEPLYLGNAGTASRFLTTVVALASPGQ-----DATTNVLTGNARMKVRPIGALVDALRSN
ARO1_NEUCR STPLYLGNAGTASRFLTSVAALCNPS------DVNSTVLTGNARMKQRPIGALVDALRAN
ARO1_SCLS1 PTELYIGNAGTASRFLTTVVSLCKPSA-----STKSTILTGNARMKVRPIGPLVDSLRAN
D5G8D9_TUBMM GDELYLGNAGTAARFLTSVATLVSPSG-----EHDSIVLTGNARMKQRPIGSLVDALRSN
ARO1_SCHPO KEELYLGNAGTAARFLTGIAALVSSKD-----G-AKVVLTGNHRMKVRPIGPLVDALRAN
ARO1_PNECA QMELYLGNSGTTARFLTSICTLVQPNS-----RENHLILTGSNRMKQRPIGPLVDALKNN
ARO1_CANAL GEELYLGNAGTASRFLTTVASLVGKSQ-----ASDDVILTGNARMQERPIGPLVDALGSN
ARO1_YEAST ADPLYLGNAGTASRFLTSLAALVNSTS-----SQKYIVLTGNARMQQRPIAPLVDSLRAN
ARO1_YARLI AQELYLGNAGTASRFLTTAATLVQKGD------KDHVILTGNKRMQERPIGPLVDALRSN
ARO1_COPC7 GKELYLGNAGTAARFLTTVCALAQPAPASVQPPSTNTVITGNARMKQRPIGPLVDALRAN
ARO1_CRYNJ GKELYLGNAGTASRFLTTVCAMVSGSASSER----STVITGNARMKQRPIGPLVDALTAN
ARO1_USTMA DKQIYLQNAGTAARFMATVVSLVHNDGNQHP-----VVITGNKRMKERPIAALVDALRSN
E3KTD2_PUCGT GKHVYLGNAGTAARFLTTVCSLVKSQVSNQS----STVITGNARMQERPIGPLVDALRTN
F4PAP8_BATDJ --ELYLGNAGTASRFLTTVCTLIKSSAINVE----SAVLTGNARMKQRPIGPLVDALVDN
I1CAL1_RHIO9 DKELYVGNAGTASRFLTTVLTLIPTNEGA---KNSAAILTGNARMKQRPIAPLLEALKAN
I7MKQ2_TETTS EKEIYVNNSGTSARFICSMLLLLKPNQ--------SVVIRCCERMKERPIKDLIEALSDF
::: *:**::**: : :: **: *** *:.:*
D0NXA2_PHYIT GCDISYLENEGCPPLAIRGS--GLRG----GAVRLAAKVSSQYVSSVLISAPYA--KEPL
H3GHV1_PHYRM GCDISYLETEGCPPLAIRGT--GLRG----GTVRLAAKVSSQYVSSVLISAPYA--KEPL
A9V1N3_MONBE DCAIDYLDQEGYPPLRVHGT--GLPG----GTIQLAATVSSQYVSSILLAAPYA--QAPV
ARO1_EMENI GASIEYVERTGSLPLKIAAS-GGFAG----GNINLAAKVSSQYVSSLLMCAPYA--KEPV
ARO1_ASPFU GAQIEYVENKGSLPLKIAAS-GGFTG----GQINLAAKVSSQYVSSLLMCAPYA--KEPV
ARO1_AJECG GASIEYLENLGCLPLKIASS-GGFAG----GEINLAAKVSSQYVSSLLMCAPYA--KTPV
ARO1_PHANO GIDVDYQEKEGSLPLRISAC-GGFGSEAFSGEIELTANVSSQYVSSILLSAPYS--KKPV
ARO1_FUSV7 GVEIEYQGKENSLPLRVDAA-GGLKG----GVIELAATVSSQYVSSILMAAPYA--KNPV
I1RK93_GIBZE GLEIEYLGKENSLPLRIDAA-GGFKG----GDIELAATISSQYVSSILMAAPYA--KNPV
ARO1_NEUCR GVGVKYLEKEHSLPVQVDAA-GGLAG----GVMELAATISSQYVSSLLMAAPYA--REPV
ARO1_SCLS1 GVDIEYLEKEHSLPLNVAAS-GGFTG----GDINLAATVSSQYVSSLLMCAPYA--KNPV
D5G8D9_TUBMM GSSVEYLESQGSLPVRVPST-SGLMG----GRIELEAKVSSQYVSSVLICAPYA--REPV
ARO1_SCHPO GCEINYLEKQGSLPLDLSSK-NGLKG----GIIELAATVSSQYVSSILMCAPYA--SQPV
ARO1_PNECA GCCIEYLELENCLPLLIKPKEIGLYG----GNINLSATVSSQYVSSILMCSPYA--KTQV
ARO1_CANAL GSEIEYLNKQGSLPLKISAG-NGLKG----GRIELAATISSQYVSSILMCAPYA--KEPV
ARO1_YEAST GTKIEYLNNEGSLPIKVYTD-SVFKG----GRIELAATVSSQYVSSILMCAPYA--EEPV
ARO1_YARLI GADIAFQNAEGSLPLKIEAG-VGLKG----GLIEVAATVSSQYVSSLLMCAPYA--QTPV
ARO1_COPC7 GCSIGYRESEGCLPLSIP--PNSFKG----GKIQLAASVSSQYVSSILLCAPYAQDANGV
ARO1_CRYNJ GAKVKYLESTGCLPLDID--TDGFRG----GHIQLAASVSSQYVSSILLCAPYA--AEQV
ARO1_USTMA GTSIDYLEGHGCLPLAVKGTTHGFKG----GKIQLSATISSQYVSSILLCAPYA--AEQV
E3KTD2_PUCGT GVQIDYLRNEGCLPLRIS-PEDGFPG----GMIELAASVSSQYVSSVLLSAPFA--QAPV
F4PAP8_BATDJ HCDIQYLGTKGCLPISIKSSPTGLSG----GTIHLSASVSSQYVSSILISAPYA--SSPV
I1CAL1_RHIO9 NAQIVSTEKEGFLPIAVTPN-GGFKG----GRIELAASISSQYVSSILLCAPYA--IEPV
I7MKQ2_TETTS LN-FEYLEKEFYLPFRVTKK-YEFKG----GDIHINSKISSQYVTGILMAAPYA-LEPVR
. *. : : . * :.: :.:*****:.:*:.:*::
D0NXA2_PHYIT VLELEEKEPTSLPYILMTTQLMKQFGIPVETLAP-------NRYRVPCGVYQNPKE-VSV
H3GHV1_PHYRM VLELDEEQPTSLPYILMTTQLMQQFGIPVETLAP-------NRYRVPCGVYENPKE-VSV
A9V1N3_MONBE TLEL-VGEVVSQPYIDMTVALMKQFGVDVEAHSG-------SRYVIPNTGYQLPDT-FDV
ARO1_EMENI TLRLVGGKPISQPYIDMTTAMMRSFGIDVQKSTT-----EEHTYHIPQGRYVNPAE-YVI
ARO1_ASPFU TLKLVGGKPISQPYIDMTTAMMRSFGIDVKKSTT-----EEHTYHIPQGRYINPAE-YVV
ARO1_AJECG TLRLVGGKPISQPYIDMTTAMMRSFGVEVKKSET-----EEHTYHIPLGFYTNPVE-YIV
ARO1_PHANO TLRLVGGKVISQPYIDMTIAMMASFGVQVKRDQS-----DPNTYRIPNKPYTNPAE-YVV
ARO1_FUSV7 TLRLVGGKPISQPYIDMTISMMASFGVHVTASSD-----EPNTYHIPQGQYQNPSE-YII
I1RK93_GIBZE TLRLVGGKPISQLYIDMTIAMMASFGIDVEVSSK-----EPNTYHIPKGAYKNPPE-YTI
ARO1_NEUCR TLRLVGGKPISQPYIDMTIAMMASFGVQVQRSAE-----DPNTYYIPQGTYKNPET-YVV
ARO1_SCLS1 TLRLVGGKPISQLYIDMTTAMMAAFGIHVVRSQT-----EEHTYHIPQGVYKNPEE-YVV
D5G8D9_TUBMM TLSLVGGKPISQLYIDMTIAMMSSFGIDVTKSTA-----EEYTYHIPQGSYKNPAV-YVV
ARO1_SCHPO TLKLVGGKPISQLYIDMTIAMMASFGVNVTKSTT-----EENTYNIPCGKYQNPPH-YEI
ARO1_PNECA TLSLIGGKPISQPYIDMTISMMSSFGIKVTRSHS-----KENTYYIPKGCYTCPSE-YII
ARO1_CANAL TLALVGGKPISQLYIDMTCAMMKSFGIEVTKSTT-----EEYTYHIPKGTYKNPSE-YVI
ARO1_YEAST TLALVGGKPISKLYVDMTIKMMEKFGINVETSTT-----EPYTYYIPKGHYINPSE-YVI
ARO1_YARLI TLSLVGGKPISQFYIDMTIAMMADFGVVVTKDET-----KEHTYHIPQGVYTNPEE-YVV
ARO1_COPC7 TLELVGGEVISQPYIDMTIAMMKTFGVEVTRRTD-ASGKLLDIYDIPRGTYVNPPV-YNI
ARO1_CRYNJ TLELTGGQVISQPYIDMTIAMMKQFGATVERQKD-EQGNLLDIYVIPKCTYVNPPE-YSV
ARO1_USTMA VLELVGGQVISQLYIDMTIAMMATFGIKVERLLDPTTGRPSNTYRIPKGHYVSPDV-YDI
E3KTD2_PUCGT TLSLVGGTVISQPYIDITISMMSTFGIQVERLNNPATGLPSNTYRIPNGTYKNPPV-YEI
F4PAP8_BATDJ TLDLDGDAVVSQPYIDMTIAMMKSFGIHVTRIPG------TNKYNIPQGIYTNPTE-YMV
I1CAL1_RHIO9 ELVLTGGQVISQPYIDMTIAMMESFGAEVERLPE-------NTYRIKQTTYKNPEH-YLV
I7MKQ2_TETTS VILSQTEQITSEPFIQMTFDMMKQFGSNIYREKQ-------NIFNISNTKYLYPKESYYI
: * :: :* :* ** : : : * * :
D0NXA2_PHYIT EVDASSATYPLAFAAITGGQVTVEALGNTSLQGDAAFH-TLLRSMGCTTTQDATSTTVTG
H3GHV1_PHYRM EVDASSATYPLAFAAITGGQVTVEALGNTSLQGDAAFH-TLLRSMGCTTTQDATSTTVIG
A9V1N3_MONBE ESDASSASYPLAMAAISGGRVTVAAMGSGSLQGDAAFC-RVLERMGCEVEQTSDATTVVG
ARO1_EMENI ESDASSATYPLAVAAVTGTTCTVPNIGSASLQGDARFAVEVLRPMGCTVEQTETSTTVTG
ARO1_ASPFU ESDASSATYPLAIAAVTGTTCTIPNIGSKSLQGDARFAVDVLRPMGCTVEQTDTSTTVTG
ARO1_AJECG ESDASSATYPLAAAAITGTSCTVPNIGSKSLQGDARFAVDVLRPMGCAVDQSDFSTRVTG
ARO1_PHANO ESDASSATYPLAIAAITGTTCTVPNIGSGSLQGDARFAIEVLKPMGCKVEQTKTSTTVTG
ARO1_FUSV7 ESDASSATYPLAIAAITGTTCTIPNIGSKSLQGDARFAVDVLQPMGCTVNQSDYSTTVTG
I1RK93_GIBZE ESDASSATYPLAVAAITGTKCTIPNIGSKSLQGDARFAVDVLRPMGCSVEQSDYSTTVTG
ARO1_NEUCR ESDASSATYPLAIAAITGTTCTVPNIGSKSLQGDARFAIEVLRPMGCTVEQTDVSTTVTG
ARO1_SCLS1 ESDASSATYPLAVAAISGTTCTIPNIGCKSIQGDARFAIDVLKPMGCKVVQTDYSTTVTG
D5G8D9_TUBMM ESDASSATYPLAIAAITGNTVTVPNIGRKSLQGDARFAVDVLRPMGCTVEQSDYSTTVRG
ARO1_SCHPO ESDASSATYPLAIAAITGTKCTVPNIGSASLQGDARFACDVLRPMGCTVEQTATSTTVQG
ARO1_PNECA EGDATSATYPLAIAAITGGSCTISNVGSASLQGDSKFSEYILKPMGCEVVQSPTTTYIKG
ARO1_CANAL ESDASSATYPLAFAAMTGTSCTIPNIGSSSLQGDAKFAVDVLKPMGCKVEQTTTSTTVTG
ARO1_YEAST ESDASSATYPLAFAAMTGTTVTVPNIGFESLQGDARFARDVLKPMGCKITQTATSTTVSG
ARO1_YARLI ESDASSATYPLAYAAMTGHTVTVPNIGSKSLQGDARFAIDVLKAMGCTVEQTATSTTVTG
ARO1_COPC7 ESDASSATYPLAVAAITGTKCTIENIGSSSLQGDAKFAVEVLQKMGCEVHQTADETTVQG
ARO1_CRYNJ ESDASSATYPLAIAAITGTTCTISNIGSSSLQGDARFAKEILEPMGCIVEQTLTSTKVTG
ARO1_USTMA ESDASSATYPLAIAAITGTECTVPNIGSASLQGDARFAKEVLEPMGCTVVQTATSTTVIG
E3KTD2_PUCGT ESDASSATYPLAMAALNGLSITLETIGSGSLQGDAQFAKKVLEPMGCQVIQTERETKVIG
F4PAP8_BATDJ EADASSATYPLAFAAITGSTVTVTNIGSNSLQGDAMFAIRVLKEMGCSVHQTETTTTVQG
I1CAL1_RHIO9 ESDASSATYPLAIAAITGTTCTVTSIGSSSLQGDAGFAVNVLKPMGCTVVQTETSTTVTG
I7MKQ2_TETTS EPDAATASYDMAWAVLNQKKIIIKGFQIHSLQGDLKFTEKLVGLGYCVEYNDVGVIIRGD
* **::*:* :* *.:. : . *:*** * :: * : .
D0NXA2_PHYIT PQ-DGTPLKAVEIDMETMTDAFMTAVALAAVA--------------DGTTKITGIANQRV
H3GHV1_PHYRM PQ-DGTPLKAVDIDMETMTDAFMTAVALAAVA--------------DGTTKITGIANQRV
A9V1N3_MONBE CV-PGT-LQPVDVDMGDITDTFMTAAVLMATCPK------------GSRSTITNIANQRV
ARO1_EMENI PSD-GILRPLPNVDMEPMTDAFLGASVLAAIARGK-------ES--NHTTRIYGIANQRV
ARO1_ASPFU PAD-GVLRPLPNVDMEPMTDAFLGASVLAAIARGK-------DS--NHTTRIYGIANQRV
ARO1_AJECG PPG-GILSPLPNIDMEPMTDAFLTASVLAAVARGK-------GS--NHTTRIFGIANQRV
ARO1_PHANO PPR-GELKAVKEIDMEPMTDAFLTASVLAAVCSSN-------GT--STTTRIYGIANQRV
ARO1_FUSV7 PAP-GELKGLPHVDMEPMTDAFLTASVLAAVASG--------------KTQITGIANQRV
I1RK93_GIBZE PAP-GQLKALAHVDMEPMTDAFLTASVLAAVASG--------------TTQITGIANQRV
ARO1_NEUCR PPI-GTLKAIPHVDMEPMTDAFLTASVLAAVASG--------------TTQITGIANQRV
ARO1_SCLS1 PPI-GSLQAIEEVDMEPMTDAFLTASVLGAVAKG--------------TTKIRGIANQRV
D5G8D9_TUBMM PPK-GQLRPLPHVDMEPMTDAFLTASVLAAVAKGV-------E-----RSSITGIANQRV
ARO1_SCHPO PPK-GTLKPLESIDMETMTDAFLTASVVAAVACNV-------SEG-DPVTRITGIANQRV
ARO1_PNECA PPK-GKLKSLGSINMESMTDTFLTAAVLASVAYEE-------SK--PYVTKITGISNQRI
ARO1_CANAL PPR-GHLKPLPHVDMEPMTDAFLTASVVAAVAK------------GGSSTSITGIANQRV
ARO1_YEAST PPV-GTLKPLKHVDMEPMTDAFLTACVVAAISHDS-------DPNSANTTTIEGIANQRV
ARO1_YARLI VP---NLKAIA-VDMEPMTDAFLTACVVAAVSE--------------GTTVITGIANQRV
ARO1_COPC7 PP-LGQLKAIEEVDMEVMTDAFLTASVLAAVAN----------GGENKAMKITGIANQRV
ARO1_CRYNJ PP-VGTLRALGNVDMEPMTDAFLTASVLAAVAVKPCLPERKVEGLPETASRIYGIANQRV
ARO1_USTMA PK-LGQLRQIGLVDMEPMTDAFLTASVLLAVAAHS--PANGSTSNARPSTRITGIANQRV
E3KTD2_PUCGT PSTVSELRQLGEIDMEEMTDAFLTACVVLGVAVQP------SEKEQKMSTRIIGIANQRV
F4PAP8_BATDJ PE---QLVPLPCIDMETMTDAFMTATVLAAVAQSN-------GNVDDNTTRITGIANQRV
I1CAL1_RHIO9 PPI-------------------------------------------ENITRIHGIANQRV
I7MKQ2_TETTS LPQ--KECTQTTFDFNDCTDTFITFGIILAALENN----------NNQSYKIVNIANQRV
* .*:***:
D0NXA2_PHYIT KECNRIEVMVTELSKIGVECGELPDGIWI--KGTAGKTEHLK----KVSIACHNDHRIAM
H3GHV1_PHYRM KECNRIEVMVTELHKIGVECGELPDGIWI--KGTAGKTDHLK----QASIACHNDHRIAM
A9V1N3_MONBE KECNRITAMLTELGKCGVHCEELETGLAIFGQGADSPASLKR----GVPVECYRDHRIAM
ARO1_EMENI KECNRIKAMKDELAKFGVICREHDDGLEIDGIDRSN-LRQPV-----GGVFCYDDHRVAF
ARO1_ASPFU KECNRIKAMHDELAKFGVVCREHDDGLEIDGIDRST-LRQPA-----GGVFCYDDHRVAF
ARO1_AJECG KECNRIKAMKDELAEFGVVCREHDDGLEIDGIDRAT-LHHPS-----DGVYCYDDHRVAM
ARO1_PHANO KECNRIQAMEDELAKFGITCRQFDDGIEVDGRG-YQ-LDAPK-----VGIHCYDDHRVAM
ARO1_FUSV7 KECNRIAAMKDQLAKFGVQCNELDDGIEVLGKGQDGGISAPT-----VGIHCYDDHRVAM
I1RK93_GIBZE KECNRIAAMKDQLAKFGVQCNELEDGIEVIGKGQDGGVSTPE-----ASIHCYDDHRVAM
ARO1_NEUCR KECNRILAMKDQLAKFGVHCNELEDGIEVIGIPYTE-LKNPT-----EGIYCYDDHRVAM
ARO1_SCLS1 KECNRIKAMKDELAKFGVTCRELEDGIEVDGVPIKD-LKHPA-----EGIHCYDDHRVAM
D5G8D9_TUBMM KECNRIAAMVHELGKFGVTAGELEDGIWIQGIDYNL-LKTP------EGVHCYDDHRVAM
ARO1_SCHPO KECNRIAAMVHELAKFGVRTGELEDGIYIFGKNYKE-LKKPE-----EGIYTYDDHRIAM
ARO1_PNECA KECNRINAMVCELKKFGIEAGELPDGIYVKALNTSN-LPYSV-----EGINCYNDHRIAM
ARO1_CANAL KECNRIEAMVTELAKFGVPANELPDGIEIHGID-IEDLKTPEISKR--GVSSYDDHRVAM
ARO1_YEAST KECNRILAMATELAKFGVKTTELPDGIQVHGLNSIKDLKVPSDSSGPVGVCTYDDHRVAM
ARO1_YARLI KECNRIEAMRVQLAKYGVVCRELEDGIEVDGIS-RSDLKTPV------SVHSYDDHRVAM
ARO1_COPC7 KECNRIRAMMDELAKFGVHTTEQELGLTIYAVPISQLKK-------NVSVHCYDDHRVAM
ARO1_CRYNJ KECNRIQAMRDQLAKFGIETDEFDDGIIIFGKPEASLFR-------GASIHCYDDHRVAM
ARO1_USTMA KECNRIRAMMDELAKFGVNTKEHDDGLEIFGIDYRQLHA-------NVRVHCYDDHRVAM
E3KTD2_PUCGT KECNRIAAMVAELGKMGIHAQELEDGIEVFGTPVDALAKRGD----QVRINCYDDHRIAM
F4PAP8_BATDJ KECDRIAAMIQQLDLFGVCASELPDGIQIHGMDRSKLCHTKP----LSGVHCFDDHRIAM
I1CAL1_RHIO9 KECNRIAAMVHELTKFGVQASELPDGIQIHGKPIKDLKAPKE------GVHTYDDHRIAM
I7MKQ2_TETTS KECDRIHALSLNLKKFGIKTIEYDDGIEIFPNKKQLLEQCDS--KQSIIIECFNDHRLGM
***:** .: :* *: : *: : : . ***:.:
D0NXA2_PHYIT SFAVLGSVVD-----------NIIITDKECTDKTYPEFWDHVQMHLGLQVAPVVEEKINN
H3GHV1_PHYRM SFAVLGSVVG-----------NVVITDKECTDKTYPEFWDHVQMHLGLQVAPVVEETTDS
A9V1N3_MONBE SFGVLGCLWP-----------NVQITDKDCTDKTYPSFWDDVCNLQGHRNAVLHASIEEQ
ARO1_EMENI SFSVLSLVTP----------QPTLILEKECVGKTWPGWWDTLRQLFKVKLEGKELEE--E
ARO1_ASPFU SFSVLSLIAP----------KPTLILEKECVGKTWPGWWDTLRQKFAVKLEGKELKEA-E
ARO1_AJECG SFSVLSLVTP----------EPTLILEKECVGKTWPGWWDSLAQTFKVKLDGKEVGKRTE
ARO1_PHANO SFGVLGLVAP----------EPVLILEKDCTGKTWPGYWDILNQQFKAELTGVEPPQQSH
ARO1_FUSV7 SFSVLAVASP----------SPVIVTERECVGKTWPGWWDILSQAFKVDMIGHE-PDANA
I1RK93_GIBZE SFSVLAVASP----------GPVIVTERECVGKTWPGWWDILFQVFKVDMVGHE-SHADT
ARO1_NEUCR SFSVLSTISP----------HPVLILERECTGKTWPGWWDTMSNYFKVHLEGEEEPHSSH
ARO1_SCLS1 SFSVLSVAAS----------QPVLIEERECVGKTWPGWWDILSKSFQVELAGKEVKATHS
D5G8D9_TUBMM SFSVISLIAP----------NPVILQERKCVEKTWPGWWDVLSTSFNVHLGGVELLE--N
ARO1_SCHPO SFSVLSLICP----------SRTLIIDKACVEKTWPYWWDVLHQSFGVKLTGATSVASDP
ARO1_PNECA SFSVLACISS----------KPTTILDKACVNKTWPYWWDILNSTFKVQMKGIEFDLNPT
ARO1_CANAL SFSLLAGLCK----------EPVLILERSTTGKTWPGWWDILHSKFKIELDGYEPPFNTD
ARO1_YEAST SFSLLAGMVNSQN-ERDEVANPVRILERHCTGKTWPGWWDVLHSELGAKLDGAEPLECTS
ARO1_YARLI SFSLLSSIMA----------APVAIEERRCVEKTWPGWWDVLSGVFNVPLEGVTLAKTVS
ARO1_COPC7 AFSVLSTVV-----------EGAIIEEKRCVEKTWPGWWDDLENKIGIKVEGVDLAGLRA
ARO1_CRYNJ AFAVLSCII-----------DETIIEEKRCVEKTWPNFWDDLQNKIGVAVEGVELETHNQ
ARO1_USTMA AFSVLASLA-----------PGAILEEKRCVEKTWPNWWDDLERKLGIRVHGVDPECSPS
E3KTD2_PUCGT AFSVLGTVPGG---------KGLILNEKRCVEKTWPSWWDDLSTKLGIQLDGVPAHEKLT
F4PAP8_BATDJ SFSILACAVDSKH------NTGVVITERECVEKTWPSWWDTLENTLGTKITGVDLPKHMH
I1CAL1_RHIO9 SFSVFSTVVP----------HGTIITDKKCVEKTWPTWWDDLEGKLGVRLNGIDLGNRLT
I7MKQ2_TETTS AFSQLGNFIKNKNG---QNSLDIILDEGDCVKKTFPSFYNHLQYSYSARCEKVHFSKSKH
:*. :. : : . **:* ::: :
D0NXA2_PHYIT TDAATSIPG----------------------------------VFVIGMRGAGKSSLAKA
H3GHV1_PHYRM NDSDTSIPG----------------------------------VFMIGMRGAGKSSLAKA
A9V1N3_MONBE TSAAAGSAGHAGARDRQ-------------------------SVCIIGMRGAGKSTLARA
ARO1_EMENI PVAASGPDRANA------------------------------SIYIIGMRGAGKSTAGNW
ARO1_ASPFU SPVLTRAEKASA------------------------------SVFIIGMRGAGKTTSGHW
ARO1_AJECG TNPIVHVNKSAA------------------------------SIFIIGMRGAGKTTSGFW
ARO1_PHANO GKKITS-KGQQK------------------------------SIFIIGMRGAGKTTAGGW
ARO1_FUSV7 DEEDSKSSVMER------------------------------SVFIIGMRGAGKTTAGNW
I1RK93_GIBZE HDEEISEKTLES------------------------------SVFIIGMRGAGKTTAGNW
ARO1_NEUCR VSHEKPRKGNPK------------------------------SIFIIGMRGAGKSTAGKW
ARO1_SCLS1 KKIGIPALP-DK------------------------------SIFIIGMRGAGKTTAGAW
D5G8D9_TUBMM PQVMEVKKGSNR------------------------------TIVIIGMRGAGKTTMGIR
ARO1_SCHPO LKGSISKNAS---------------------------------IILIGMRGAGKTTIGKI
ARO1_PNECA INSSILHHPSEC------------------------------TIFLIGMRGAGKTTLGQL
ARO1_CANAL KHVDKSSDK---------------------------------SIIVIGMRGTGKSTLSEW
ARO1_YEAST K---KNSKK---------------------------------SVVIIGMRAAGKTTISKW
ARO1_YARLI KAESGLSKP---------------------------------SIFIVGMRGAGKTHLGAQ
ARO1_COPC7 ESSSAGVKESKPIDNSS--------------------------ILLIGMRGTGKTHIGQL
ARO1_CRYNJ ASTSAKPVSPIDQSQSDR------------------------PIFLIGMRGAGKTYVGRM
ARO1_USTMA LCISPSHFTKASAASTNGKPPTCLSQLTCGKALTPRKYSKHATIICIGMRASGKTFLGAI
E3KTD2_PUCGT NTTSAVAWEAKKPETPS--------------------------ILLCGMRGSGKSFSGQV
F4PAP8_BATDJ ASKLHTTTESAACFHSSQIS--------------------QSSILLVGMRGVGKTHMGRA
I1CAL1_RHIO9 QKTLGRTHVPNKPVKNVDRN---------------------KSLVIVGMRGTGKTTLGQY
I7MKQ2_TETTS LKQEVEEIN---------------------------------TVFVIGMRCCGKSILSKK
: *** **: .
D0NXA2_PHYIT ASAALKL-DLLDTDKVLEKEFG-ESIADFVARHNHTWEAFREKQKELLLRLIANP-----
H3GHV1_PHYRM ASATLKL-NLLDTDKVLEKEFG-ESIADFVARHNHTWEAFREKQKELLLRLIANP-----
A9V1N3_MONBE AAAHLGY-QFLDLDVVLEERCE-GGIKTFVEQQG--WPAFRDAEERVLADTLRAH-----
ARO1_EMENI VSKALNR-PFVDLDTELETVE--GMTIPDIIKT-RGWQGFRNAELEILKRTLKER-----
ARO1_ASPFU VASTLKR-PFIDLDDELERIE--GMTIPDIIKQ-RGWQGFRDAELNLLQRTMKER-----
ARO1_AJECG VSKALQR-PFIDLDDELERTE--GMTIPEIIKQ-RGWGGFREAELSLLRRVMTEK-----
ARO1_PHANO ASRALGW-PLIDLDTALEQHM--SMTIPEIIKT-SGWDGFRKAELELLQRTVKEK-----
ARO1_FUSV7 MAKMLGW-KFIDLDQELERRA--GCTIPEMIRGSRGWEGFRADELSLLKDVMAKN-----
I1RK93_GIBZE MAKILGW-KFIDLDQELERRA--GCTIPEMIRGDRGWDGFRADELALLRDVMERN-----
ARO1_NEUCR MSEVLNR-PLIDLDHELERRE--GQTIPEIIRSERGWEGFRKAELELLEDVIKNN-----
ARO1_SCLS1 AAKILGR-PYKDLDVELERIS--GMSIPDMVRS-KGWDFFRAAELDLLKHCLTDQ-----
D5G8D9_TUBMM AAKILNR-PVLDLDTVLEQEQ--KSALPEIIKK-HGWDGFRKLELELLQRHLKAH-----
ARO1_SCHPO IAKQLNF-KFLDLDELLEDYL--EMPIAEVIFR-MGWDAFRLEEHKVLRKFITEH-----
ARO1_PNECA AANFLGR-EFIDLDSIIEEDI--KTTILEFIQK-YSWDVFRRKELHFLKTLLTEK-----
ARO1_CANAL LASFLGF-KMLDMDKYLEEKL--GT-GIKSLIKAKGWEYFRQEEAIVAKECFTKF-----
ARO1_YEAST CASALGY-KLVDLDELFEQQH--NNQSVKQFVVENGWEKFREEETRIFKEVIQNYG----
ARO1_YARLI AANHLGY-EFIDLDQLLEKDL--DT-TIPQLIADKGWDHFRAEELRLLKQCLNDK-----
ARO1_COPC7 AAASLPGWSFVDADHYFESKL--KTGVKDFVKN-EGWEKFREEELAVLAELIGLGVDGKA
ARO1_CRYNJ AADILSG-QFTDADDVFAQES--HQTVSEFVAA-NGWDEFRKKETEILSKFV--------
ARO1_USTMA GAAALSR-TFIDADVVFNEKLGAKDGLGDFVRE-HGWPAFRQKELEILQELI--------
E3KTD2_PUCGT AASTLGW-PLIDTDLYFQEKC--GCSIREFIQK-NDWSHFREEECAVLKEIL--------
F4PAP8_BATDJ AAKHFGR-TFIDMDVYLEQKL--LTTIPELIKA-QGWEGFRTQELQCLQDIL--------
I1CAL1_RHIO9 AAEVLGF-KFVDVDHYFENTL--NTTITEFINT-WGWEQFRVKETEMLKQILDSP-----
I7MKQ2_TETTS VSNLLHMNNLSLDDELFNQFYSQKYKNLSEAINAEGWDTFRNNELQLLKQVIKENN----
: : * : * ** : .
D0NXA2_PHYIT -------PPASIISCGGGVVETPEIVDALEKYPY----VVHVQRAMKDVLAYLDS-VEES
H3GHV1_PHYRM -------PPATIISCGGGVVETPEIVAALEKYPY----VVHVHRDIRDVLAYLDT-VEES
A9V1N3_MONBE -------PTGAVIACGGGIVEREANCAVLQATKLP---IIWLDRPLVDIERYL---AADG
ARO1_EMENI -------SRGYVFACGGGVVEMPEARKLLTDYHKTKGNVLLLMRDIKKIMDFLSI---DK
ARO1_ASPFU -------PTGHVFACGGGVVEIPEARKLLIDWHKTKGNVLLIMRDIKQVMAFLNI---DK
ARO1_AJECG -------PTGYIFACGGGVVETPEARKLLTQYHKTTGNVILVMRDIKEIMDFLKI---DK
ARO1_PHANO -------PTGHIFACGGGIVEIPEARKILVDYQKSGGIVLLVSRDINKVVEFLQI---DK
ARO1_FUSV7 -------SHGHIFSCGGGLVETPEARQLLKDYGRNGGNVLLIHRDTEQVVEYLMR---DK
I1RK93_GIBZE -------KTGHVFSCGGGLVETPEARELLNSYGANGGHVLLVHRDTDQVVEYLNR---DK
ARO1_NEUCR -------PTGHIFSCGGGIVETEAARKMLLSYSQNGGIVLLVHRDTDQVVEYLMR---DK
ARO1_SCLS1 -------PEKHVFACGGGVVEMPEARELLINFHKSGGIVLLVHRDTEQVMDYLRI---DK
D5G8D9_TUBMM -------PDSYIFACGGGIVETPVARNLLKQYCSSGGIVIHVHRNIERVMEFLSI---DK
ARO1_SCHPO -------PEGYVAASGGGVIEMDESRNLLSNFVKEGGIVLHVHRNLEHIKSYLSE---DQ
ARO1_PNECA -------KENYIISCGGGIIETEEARDLLISYIEANGIVIHIHRNIQDIIKYLNT---DK
ARO1_CANAL -------SKGYVLSTGGGIVEGEDARQQLKSYADNGGIVLHLHRDLDETVTFLAA---DT
ARO1_YEAST -------DDGYVFSTGGGIVESAESRKALKDFASSGGYVLHLHRDIEETIVFLQS---DP
ARO1_YARLI -------SEGYVISCGGGVVETPAARDALQTFKGVGGIVLHVHRPVSRILEYLNK---DQ
ARO1_COPC7 VSSPSSYSKNHVISLGGGIVETPAARSLLKAYLAKGGRVVHITRPIDEIVRYLNV---ET
ARO1_CRYNJ ----EEHRGNHVIALGGGIVETETARETLKAHVAKGGHVVHVTRALEDIEAYLDSIGNTA
ARO1_USTMA ----ARHPSGALISLGGGVVETEACRQILAEYAQTKGPVIYIVRDTNAIVKFLAT----S
E3KTD2_PUCGT ----KEFPSRHVISLGGGIVETEKGRKMLMDYANSKGPVVEIIRPVEEVIAYLNE---DG
F4PAP8_BATDJ ----VTYPTGAVIASGGGIVETPDARSALENWS---GTVIHIRRDIDEVEAYLGV---DT
I1CAL1_RHIO9 ------YARDHVISCGGGIVETAENRELLKKHHSNGGKVLHLVRDLDQVVKYLNR---DK
I7MKQ2_TETTS ---LQKKYKNTIIACGGGIITIPEARELLRKQK----YVIWLRRDFADIQKDFDK---RQ
: : ***:: * :: : * :
D0NXA2_PHYIT HRPSL--GDSHANVWARREPLYQRSSTFEFVV--------------------NAGDVDYP
H3GHV1_PHYRM HRPSL--GDSHANVWARREPLYQRSATFEFVV--------------------TAGDVDYP
A9V1N3_MONBE VRPAY--LEEVAEVYARRQPRFAACADWRFPV--------------------AEGATDLL
ARO1_EMENI TRPAY--VEDMMGVWLRRKPWFQECSNIQYY-------------------SRDASPSGLA
ARO1_ASPFU TRPAY--VEDMLGVWLRRKPWFQECSNIQYY-------------------SQHAS-AGLP
ARO1_AJECG TRPAY--VEDMMSVWLRRKPWYEECSNVQYY-------------------SRLTGLDGMT
ARO1_PHANO TRPAY--VEDMMGVWLRRKPWYVECSNYRFH-------------------SQAAGSKALA
ARO1_FUSV7 TRPAY--TSEIREVYLRRKDFYQECSNLLYYS------------------PHSESSGSKS
I1RK93_GIBZE TRPAY--TSEILQVYLRRKDFYNECSTHLYYS------------------PHSESSGRQS
ARO1_NEUCR SRPAY--SENIREVYYRRKPFFEECSNFRYYS------------------PHPDGSKALT
ARO1_SCLS1 TRPAY--VEDMMGVYSRRKPWFNECSNFQYHS------------------KGS-GASALS
D5G8D9_TUBMM TRPAY--VEDMVGVWNRRKPWYTECSNYQYY-------------------SPIVSESDLA
ARO1_SCHPO TRPTYKDQESIDDVYKRRHVWYRECRSHYF------------------ISPVLSNQVIDE
ARO1_PNECA TRAPY--QDNIMHVWERRKRWYNLCSSHQFHMTS--------------TDPTEFKKNIPL
ARO1_CANAL TRPAY--SSEVQEVWLRREKWYHECSNYHFYS------------------SHCSTEDEFN
ARO1_YEAST SRPAY--VEEIREVWNRREGWYKECSNFSFFA------------------PHCSAEAEFQ
ARO1_YARLI SRPAF--VDDLEAVWQRRKELYRSVSSNVFFA------------------PHCDSAEATA
ARO1_COPC7 ARPAY--EEPILDVWKRREPWYKECSGWEFGNVVVEAPQGQAQAANVEAGPGKTKCVKTL
ARO1_CRYNJ VRPNW--GETFADVFKRREPWYQACSSHEFYNVL-------------EAVGGQTHEEHTK
ARO1_USTMA DRPAY--GEPVMDVYRRRNPWFSECSSAELVSYS-EGESLAIQPCAMNVPDPSFTIQKKF
E3KTD2_PUCGT NRPSL--GESIEQIWARREPWYRLCSNSEYFNLV-------------HPTIDHALISEVQ
F4PAP8_BATDJ TRPSF--GQDVRSVFARRAPLYTECSSAEFVIPT---------------SLNQANAAYWN
I1CAL1_RHIO9 TRPMF--GEDMLNVWRRRRAWYKEVCNYEFIAYA-----------ASLLENGYVSPTEWV
I7MKQ2_TETTS NTPDY--QNTLKGDYEQRRPYYEQVSNFIFNFPG-----------YTFFSKSIGEKEYWK
. . : :* :
D0NXA2_PHYIT RIDRDFVRFLSVVIPGLPTSF----DYRSSCRSDTFFLSLTFPDLNDA-------HSLID
H3GHV1_PHYRM RLDRDFVRFLSVITPGLPTNF----DYRSSCRADTFFLSLTFPDMNDA-------RPIIS
A9V1N3_MONBE CWKQHFGRLCA-----LATGL----SPRVPAWVYSKFVCLTQPDVRAVP------AAQLA
ARO1_EMENI RASEDFNRFLQVATGQIDS------LSIIKEKEHSFFASLTLPDLREA-------GDILE
ARO1_ASPFU RASEDFARFIKFVTGLDDS------LGTIKKKQHSFFVSLTLPDVRGA-------DQILE
ARO1_AJECG QVSGGFNRFLKVITGEVDS------LAKMRRKENTFFVSLTLPDLSLA-------AHILK
ARO1_PHANO HTQTEIGRFLNIITGRTST------LQDIKKKKQSFFVCLSAPNLEPC-------AKDLP
ARO1_FUSV7 EIPCDFQQFVSSISGRSTH------LKDVMEKDHSFFVSLTVPDVSEA-------ASLIP
I1RK93_GIBZE HIPHDFRQFVHSIAGKTTH------FKDVLDKDHSFFVSLTVPDVDQA-------VNLLP
ARO1_NEUCR EPPFDFSQFLSVICGHSNH------LEEVKKKPHSFFVSLTVPNVSKA-------LDIIP
ARO1_SCLS1 VAEQDFARFLHHISGKSLH------FDEMRNKPQSFFVSLTMPDISGA-------AYILP
D5G8D9_TUBMM IAQADFSRFLAIVTGNSDY------HERLLKKTRSFFVSLTFPNLEEV-------TGAIN
ARO1_SCHPO KIQYSMSRFLDVVTGSSQV------LQKFKTKKRSTFLTLNYPRIEDA-------LPTLR
ARO1_PNECA NLKSSFNNFLRTITGKNNI------FSLILKKKRSYFLSLAFSDLENI-------FSLLD
ARO1_CANAL HLRRSFVNYIKLITGAERP------VVPAGR---SAAVVLTSPDLNEV-------VGDLE
ARO1_YEAST ALRRSFSKYIATITGVREI------EIPSGR---SAFVCLTFDDLTEQ-------TENLT
ARO1_YARLI KVQQMLGAFLDRVTGKSEF------VIPHKDQ-FTSFLSLTFPDVSIA-------ATMLP
ARO1_COPC7 AGRNEVKRFFGHLAGINPNFTHGGSVEGQ--QRRTYFLCLTYPDVRHA-------FPYID
ARO1_CRYNJ AMRAECGRFFKFITGRESN----RPRLSV--GNPTSFLSLTFPDVTPA-------LIHLD
ARO1_USTMA GLETEVARFFKFVVGQDTNQIRDLVVDSRKGGRRTYFLSLTFPDVVPK-------LELIR
E3KTD2_PUCGT HAKRAMRQFFRFITGVDTN----HVLLDPPVPRNTHFLCLTFPSLSPCREEDKNILDRFE
F4PAP8_BATDJ KVEQSFMQFLHFKLATTKP------NVNDKSLDTSYFVSLTFPNVVSA-------AALVE
I1CAL1_RHIO9 AIKKDLQRYLNFIWGRDTNQ---VNITPSRVGTPTTFVSLTSKDLSTC-------IEKLV
I7MKQ2_TETTS RVEKSFKGYIKSIFNKQVRKG---GQDEYLYAEESHFLCLQFEDLQRLT------FADLV
: * : .
D0NXA2_PHYIT DISKGADALELRVDLLKYAEDT-----------KFVAAQVALLRSLST-LPIIFTVRSKV
H3GHV1_PHYRM DISKGADALELRVDLLKYPQDT-----------KFVAAQVALLRTLSS-LPIIFTVRSKG
A9V1N3_MONBE EIVANAQAVELRVDLLASLTE------------DYIATQVAAIRSATK-SPIIFTVRTEP
ARO1_EMENI EVCVGSDAVELRVDLLKDPASNN-----DIPSVDYVVEQLSFLRSRVT-LPIIFTIRTQS
ARO1_ASPFU QACVGSDAVELRVDLLEDPDSSN-----GIPTVDFVADQISYLRSRIT-LPVIFTIRTKG
ARO1_AJECG EVTLGSDAVELRVDLLKDPQSDN-----EIPSVDYVAEQISVLRSRTS-VPLVFTIRTKG
ARO1_PHANO EIVVGADAVELRVDLLEDPEGSE-----GLPTPEFVIEQLTILRNVTT-IPVIFTLRTKA
ARO1_FUSV7 EVVVGSDAVELRVDLLQDRS------------VDSVTRQVSILRALAK-KPIVFTLRTVS
I1RK93_GIBZE EVVVGSDAVELRVDLLQDRS------------IDSVIRQVSTLRASAK-KPIVFTLRTES
ARO1_NEUCR KVVVGSDAVELRVDLLEDYD------------PEFVAKQVALLRSAAR-IPIVYTVRTVS
ARO1_SCLS1 SVAVGSDAVEVRVDLLEDPSSTN-----GIPGTDFLSVQIAHLRSVVH-LPVIFTVRTVS
D5G8D9_TUBMM SVTIGSDAVEVRIDLLIDPTDSN-----GVATPAFVSEQLAVLRGKTQ-LPVVFTIRTKS
ARO1_SCHPO DVTVGCDAIEVRVDYLKDPKSSN-----GISSLDFVAEQISLLRCSTT-LPIIFTIRTIS
ARO1_PNECA IITAGCDAIEIRIDLFQKPEEID-----KYPSLEYIAEKIFLLRQKTS-LPLIYTLRTTN
ARO1_CANAL SITIGADAVELRVDLFKDT------------SAEFVAAQIAVIRKHAD-LPIIYTVRTVS
ARO1_YEAST PICYGCEAVEVRVDHLANY------------SADFVSKQLSILRKATDSIPIIFTVRTMK
ARO1_YARLI SLSEGCSALELRVDLLNENDEA-------IPSEEYVLSQLAILRQNVD-LPILYTVRTKA
ARO1_COPC7 ELTEGADALELRVDLLKDA--KAPE--APFPSVAYVKDQVTALRRVTG-LPIIYTVRTKA
ARO1_CRYNJ ELTEGADAVEFRVDLLSTTGQAPTR--PALPPISFVAKQLASLRLATT-LPIVFSVRSKD
ARO1_USTMA SMESGSDALEFRADLLNPSGQPVTT--PQIPPTEYVKNQLAALRHRTS-LPIVFTVRTHS
E3KTD2_PUCGT ELTVGCDAVELRVDLLSTSGKAPTS--PSIPPTEFVVKQVAALRRLTT-LPIIYTVRTCS
F4PAP8_BATDJ QVTEGANAIELRVDLLEST------------KPDFVGSQVAMLRHLSK-LPIVYTVRTQS
I1CAL1_RHIO9 EVCEGADAVELRVDLLKKPEEKE-----GISDIEYVGEQLALLRRTVS-IPVIFTVRSKS
I7MKQ2_TETTS YIQKNFHALEVRADQFFENNFDNLSFNNNYALLEHFTLVLSRLALICNKLILIFTMRTQE
. *:*.* * : . : : :::::*:
D0NXA2_PHYIT QGGAFPDGEEHEKKMFELLQLGVRLGCEFVDMETCW-SRK-----AREQLLAHRHRSAII
H3GHV1_PHYRM QGGAFPDGEENELKMFELLQLGVRLGCEFVDMETCW-SRK-----AREHLLAHRYRSAII
A9V1N3_MONBE QGGRYAGSPA---KYAALLRVGIRLGCEIVDVEADLPSDE-----LRQLTRLVPASTTLL
ARO1_EMENI QGGRFPDNAHD--AALELYRLAFRSGCEFVDLEIAFPEDM-----LRAVTEMKGFSKIIA
ARO1_ASPFU QGGRFPDDAHA--EAMQLYRLAVRSGCEFVDLEIAFPDEM-----LRAVTEMKGYSKIIA
ARO1_AJECG QGGRFPDDAYD--AALQLYRLAVRMGSEFVDLEISFPEQL-----LRTVTEMKGFSKIIT
ARO1_PHANO QGGKFPDEAYA--EARSLYQSAIRLGCEFVDLEMTMPEEV-----LREVSETRGFTEIIA
ARO1_FUSV7 QGGKFPDEAYE--EGLELYRLALRMGMEYVDVEMTLPENI-----IQTVTESRGHSRIIA
I1RK93_GIBZE QGGKFPDSAYD--EGLELYRLAVRMGMEYIDVEMTLPDEM-----IKTVTESRGYSRIIA
ARO1_NEUCR QGGKFPDDDYE--LALKLYRTGLQAGVEYLDLEMTMPDEV-----IEAVTNEKGYTHIIA
ARO1_SCLS1 QGGRFPDAAHE--EALKLYKLAVKMGIEYIDLEIAFPDEL-----LQEVTEAKGFSRIIA
D5G8D9_TUBMM QGGKFPDEDHQ--RALELYLAGIRMGLEYIDLETTWPVAL-----LEKVTSGKGYSKIIA
ARO1_SCHPO QGGLFPNDKEE--EAKELMLSAMRYGCDFVDVELGWSSET-----INILYQHKGYTKLIM
ARO1_PNECA HGGSFLSSEKK--LAKEYILHGAKWGFEFLDIELDIASEL-----FKTINNSWPYTKIIA
ARO1_CANAL QGGKFPDENVD--ELKSLLLLGIRLGVAYVDLQLTAPNEL-----IEEISSKKGFTRVIG
ARO1_YEAST QGGNFPDEEFK--TLRELYDIALKNGVEFLDLELTLPTDI-----QYEVINKRGNTKIIG
ARO1_YARLI QGGRFPDDKPV--ELANLVNLGLKTAVELLDVELTYPAEL-----VSSVGASRGYTKLLG
ARO1_COPC7 QGGAFPDGNAK--EYKELVEAGVRLGVEYLDVEVASIFSDKEVADLSKRTKKAGSTLVIA
ARO1_CRYNJ QGGMVPSDNAE--AYGALVRLGLRCACEYVDLEVCWPEQL-----LDSIVQLKRETHIIA
ARO1_USTMA QGGMFPDGKQH--EYFELISLALRHACEYIDLELGWDDDL-----LSAVVQAKGNSQIIA
E3KTD2_PUCGT QGGMFPDGQPE--EWCKLAAMGFRTGCEYVDIELGLSPEQ-----QKALCSQKGHSKIIA
F4PAP8_BATDJ QGGRFPDDKTR--DMISLLELGIRLGCEYIDVEFTAPFER-----FSSITKSKGNSLIIG
I1CAL1_RHIO9 QAGAFSDNDEE--GMFELLRWGQRWGCEYIDVEICWNAQT-----IEKLVAQKEESLIIS
I7MKQ2_TETTS EGGLLQKTKNNYYQIINYIQRQNIFNYIDIEVDMIKRENS------INMKLIQQQNALIL
..* :::: :
D0NXA2_PHYIT SSFHAVQKPTSEAEAKAIFRECYSQGRVQIVKVVVKAYS-PVDALMVDRVAKDFASAWQQ
H3GHV1_PHYRM SSFHAVQKPTSEAETKLIFRECYSQGRVQIVKVVVKAYS-PQDALMVDRVAKDFANAWQQ
A9V1N3_MONBE GSLHFLRPCGGAQELTAALHNCALGGRADLLKVIFTADT-PGDALALVEAYRVLRGTLSR
ARO1_EMENI SHHDPKGELSWANMS-WIKFYNKALEYGDIIKLVGVARN-IDDNTALRKFKNWAAEAHDV
ARO1_ASPFU SHHDPNGELSWANMS-WMKYYNRALEYGDVIKLVGVARN-LDDNTALRKFKNWAEEAHDV
ARO1_AJECG SHHDPKGQLSWVNGS-WIQFYNKALQYGDVIKLVGVARS-IDDNISLKKFKTWAEEKHNV
ARO1_PHANO SHHDPKGELSWTNGS-WMKYYNRALQYGTVIKLVGVAKS-LQDNFALAEFKSWAETAHPT
ARO1_FUSV7 SHHDPQGTMSWKNAS-WIPFYNRALQFGDIIKLVGVARS-SEDNFDLAKFKSRMQEAQKT
I1RK93_GIBZE SHHDPKGTMSWKNAS-WIQYYNRALQYGDIIKLVGIART-PEDNFDLARFKSRMQEAQKT
ARO1_NEUCR SHHDPKATLSWKNGG-WIQYYNKALQHGDVVKLVGVARE-LADNFALARFKASLAAAHDK
ARO1_SCLS1 SHHDPQGTLSWKNGG-WFQHYNRALQYGDIIKLVGSAKS-IEDNFALAKFKKTMAAAHDT
D5G8D9_TUBMM SHHDLGGDLCWRNAS-WISKFNMTLKYGDVIKLIGQAKS-IQDNYDLENFRKYAAT-HET
ARO1_SCHPO SWHDLSGTWSWARPHEWMQKVELASSYADVIKLVGMANN-LNDNLELEEFRTRITNSMDI
ARO1_PNECA SYHNIEKPIS-CDDFEWIQKYKEAQHYGHIIKLVGTSSS-IEDNFFLEEFKSKFINK-KV
ARO1_CANAL TYQDINGELKWNNVEWKNKYNQGVSMNADIVRLVGKANS-IQDNLDLENFKKQNTLK---
ARO1_YEAST SHHDFQGLYSWDDAEWENRFNQALTLDVDVVKFVGTAVN-FEDNLRLEHFRDTHKNK---
ARO1_YARLI SHHDFPGALNWSSLEWENMYARAEAVPVDVVKLVGMAKS-FSDNFALENFREAHTSS---
ARO1_COPC7 SWHDWSGKMQWDGED-VKRKYDEARKFGDLVKIVGKAEK-LEDNFKLLSFVKSATSLPN-
ARO1_CRYNJ SWHDWTGDMAWDGEE-MKAKHVLCEKYGDVAKIVGTAKS-GLDNAKLAIFVGEVQSHPG-
ARO1_USTMA SWHDWSGRLDWESES-TAKIYEKACRFGDIAKIIGKATT-MEDNYSLERFRAKVSATA--
E3KTD2_PUCGT SYHDFSGRLKWDSSE-MIQRYHELKAYGDMVKLVSRAADGLEDNLAMLEFRKKHATLQKD
F4PAP8_BATDJ SYHDCRGVALWTDVC-MLDIYQDLYAHSDCIKLIGVAHN-IADSIAVSTFRNQFVPKLGL
I1CAL1_RHIO9 SWHDVQKVTPWDGKA-IETKYELAAKYGDIIKLVGVAET-IQDNFKLETFRASKQDGKN-
I7MKQ2_TETTS SKHFINHQDQQENIQTTIQQMKENMREQDILKLVLCSFT---NYEELETIRRQLTSINPK
:.: : : :
D0NXA2_PHYIT H-MPIISLCTTEAGKLTRVLNRTLTPVTHPLLP-AAAAPGQLSIEEIMTLRKQLGLLPAR
H3GHV1_PHYRM Q-MPIISLCTTEAGKLTRVLNRTLTPVTHPLLP-AAAAPGQLSIEEIMILRKQLGLLPAR
A9V1N3_MONBE ---PAIVMAMGQAGKLTRVLNDQLTPVTHRLLT-TAAAPGQLTAQQLDDMRAELGLFPKR
ARO1_EMENI ---PLIAINMGDQGQLSRILNGFMTPVSHPSLP-FKAAPGQLSATEIRKGLSLMGEIKPK
ARO1_ASPFU ---PLIAINMGGNGQLSRILNGFMTPVSHPALP-FRAAPGQLSATDIRKGLSLMGEIKKK
ARO1_AJECG ---PIIAINMGDKGQLSRMLNGFMTPVSHPSLP-FKAAPGQLSAREIRKGLSLIGEIKAK
ARO1_PHANO ---PLIAINMGEHGKLSRILNGFMAPVSHPLLP-SATAPGQLSAADIRRGLSLMGEIPTK
ARO1_FUSV7 ---PMIAMNMGKAGKLSRVLNKFLTPVSHPALP-FKAAPGQMSAAEIRRGLALLGDLDPC
I1RK93_GIBZE ---PMISMNMGKAGKLSRVLNRFLTPVSHPALP-FKAAPGQMSAAEIRQALALLGDLEPH
ARO1_NEUCR ---PLIALNMGAAGKLSRVLNGFLTPVSHPALP-SKAAPGQLSAAEIRQALALIGELEPR
ARO1_SCLS1 ---PLIAINMGVTGKLSRVLNGFMTPVSHPSLP-FKAAPGQLSAAEIRSTLSTLGEIEPK
D5G8D9_TUBMM ---RMIALNMGEKGKLSRILNTFLTPVTHPALP-FKAAPGQLSTVEIHQALSLMGMLETK
ARO1_SCHPO ---PLILFNMGRFGQLSRILNKFMTPVTHPLLP-SKAAPGQLTVKQLNEARVLIGEILPE
ARO1_PNECA ---PSIIINTGIKGQLSRIMNTFMTPVTHPSLP-SKIAPGQLSIKEINTALHIMGLLPEK
ARO1_CANAL ---PLIAFNLGSQGKLSQVLNGTFTPISHKLLP-NDEE--FLTIGELNQTYFDIGGFTAK
ARO1_YEAST ---PLIAVNMTSKGSISRVLNNVLTPVTSDLLP-NSAAPGQLTVAQINKMYTSMGGIEPK
ARO1_YARLI ---PLLAINMGSHGQLSRVTNTLLTPVTHADLP-VAAAPGQLSVEEINQTRSTIGMFNKN
ARO1_COPC7 -SPPIIAINMSTLGQSSRILNTTFTPVSHPLLP-TKAAPGQLSFKQIQQALHLLGLLPSK
ARO1_CRYNJ -AKPLLAINMGAAGQLSRILNPILTPVTHDALP-SRAAPGQLTAREILQARALTGSLPAK
ARO1_USTMA -TKPLLAVNMGSVGQLSRIVNPVFTPITHEAMP-FKAAPGQLSFRQVQTALSLIGQADAR
E3KTD2_PUCGT -RQSLITINMGRSGQMSRILSPVLSPTTHPLLPGPPAAPGQLSFRQIQTAQGLLGQIIPK
F4PAP8_BATDJ APKPLIALAMGPLGQLSRVLNTYLTPVTHASMP-MLAAPGQLTISQIHSIRHLIGMLPKK
I1CAL1_RHIO9 ----LIAINMGAAGQLSRVLNECLTPVTHPALP-QKAAPGQLSLAEINKTRHLIGLLPAQ
I7MKQ2_TETTS ----SIIIQLGKSGKLSRVQNKYLTPVYDAKFG-PPTGQGQLQKSEILQLIQELNLSSHE
: . *. ::: . ::* : : :: .
D0NXA2_PHYIT -EFFLFGSPIQKSPSPAMHNAGFESTSLASLFTYGLHDTTDVVEIVKRMQVP--NTNFGG
H3GHV1_PHYRM -EFFLFGSPIQKSPSPAMHNAGFESTSLSSLFTYGLHDTTDVLEIVKRMQAP--DTCFGG
A9V1N3_MONBE -NFFLFGEPIALSASPLMHNTVFADLKLP--YTYQRCSTSNALDAITCLQ----GTNCGG
ARO1_EMENI -KFAIFGSPISQSRSPALHNTLFAQVGLP--HNYTRLETTNAQDVQEFIRS----PDFGG
ARO1_ASPFU -RFALFGSPISESRSPALHNTLFAEMGLP--HEYTRLETANVEDVKDFIRA----PDFGG
ARO1_AJECG -KFAVIGNPVSASRSPAMHNTLFRQMGLP--HTYGTLETDNPEVAKEFIRS----PGFGG
ARO1_PHANO -KFCIFGSPISQSPSPRLHNRLFRETGLP--HTYGLHETTDASSIRDIIRA----PDFGG
ARO1_FUSV7 -NFYLFGKPISASRSPALHNTLFGQTGLP--HQYHRLETDNIQDVREVLQA----PDFGG
I1RK93_GIBZE -NFYLFGKPISASRSPALHNTLFKQTGLP--HQYHRLETDNIEDVRDVLKS----PDFGG
ARO1_NEUCR -SFHLFGNPISASRSPALHNALFRDNGLP--HQYSLFETDNAADVKDLIRA----PGFGG
ARO1_SCLS1 -SFYLFGTPISQSRSPALHNTLFKQTGLP--HRYSRLETDRVADVQDVIRA----PDFGG
D5G8D9_TUBMM -KFYIFGTPLSHSRSPALHNTLFQSLGLP--HTYHLFESADVSATKEIMNT----ENFGG
ARO1_SCHPO -KFFLFGKPIKHSRSPILHSTAYELLGLP--HTYEAFETDTVDEVQKVLNL----PDFGG
ARO1_PNECA -KYFLFGKPIKHSQSPNIHNLGFEILGLP--YKYQLFETDSISELKEILHL----EEFGG
ARO1_CANAL -KFWVIGSPIEHSRSPNLHNAGYKALNLP--YQFGRFEATDVDVVYDNLIN---KPDFGG
ARO1_YEAST -ELFVVGKPIGHSRSPILHNTGYEILGLP--HKFDKFETESAQLVKEKLLDG--NKNFGG
ARO1_YARLI LSFFIVGTPIGHSKSPILHNTMFKKLGLP--YEYSRFKTDDAAAVNAKARALLAQGNLGG
ARO1_COPC7 -HFHLFGTPIAHSMSPTLHNTGFELLGLP--FKYGLLESKEVDC-KEVRDVISDKEGFGG
ARO1_CRYNJ -KFVLFGSPIAHSVSPLLHNAGFATLGLP--HTYRLHESEKVD--QGVLEVIRSPD-FGG
ARO1_USTMA -RFALFGSPIGHSLSPLLHNTGFAALGLP--HQYELLESTEIN--DAVAAFVRSPD-FGG
E3KTD2_PUCGT -QFWLFGAPIGQSRSPLIHGTGFDTLGLEG-YRYQKCETSSVTD-STVLEKIHASD-FGG
F4PAP8_BATDJ -EYYLFGKPISESMSPVLHNTGFKQLGLP--HHYSLLETDSIDRVREVVQQGKLDGTFGG
I1CAL1_RHIO9 -SFWLIGTPIQHSMSPTLHNTGFQTLGLP--HHYGLLECHMVEYAEDAILK---DPSFGG
I7MKQ2_TETTS KKFYLFGTDIMNSPSPFIHNTCFQSLSLTT-YQYELAQISSIEDFQQYINR----QDFQG
:.* : * ** :*. : * . : . *
D0NXA2_PHYIT GSVTIPFKVDIME--HLDELSPAARAIGAVNTVMRQD---------RNGSPYWKGDNTDW
H3GHV1_PHYRM GSVTIPLKVDIMA--HLNELSPAARAIGAVNTIMRED---------RNGSPYWKGDNTDW
A9V1N3_MONBE GSVTMPLKERLGH--VLVDVDVPGRVIGAVNTIVKDS---------QGQ---LHGFNTDY
ARO1_EMENI ASVTIPLKLDIMP--LLDEVAAEAEIIGAVNTII------PVSTGKNTP-SRLVGRNTDW
ARO1_ASPFU ASVTIPLKLDIMP--LLDEITAEAEIIGAVNTVV------PVSDGEGKP-QRLVGHNTDW
ARO1_AJECG ASVTIPLKISIMP--LLDEIAPEAMSIGAVNTIVCAP---PAPDGKSQT-PRLIGHNTDW
ARO1_PHANO ASVTIPLKQDVRP--LIDGVGPEVEAIGALNTIVPEV---SIDESTGKEITRLIGRNTDY
ARO1_FUSV7 ASVTIPLKLDVMG--QVDELSEAARTIGAVNTVV------PIGKADASDRRRLLGDNTDW
I1RK93_GIBZE ASVTIPLKLDIMG--KLDELSDAARTIGAVNTVV------PFGKPDDNGCRRLLGDNTDW
ARO1_NEUCR ASVTIPLKLDIMP--LLDEVSDAAKVIGAVNTII------PVRNGDKVTLR---GDNTDW
ARO1_SCLS1 ASVTIPLKLDIIP--LLDSVTDAVKVIGAVNTII------PTPDNPP----RLVGENTDW
D5G8D9_TUBMM ASVTIPHKISIIP--LLSSISAHAQAIGAVNTVI------PVTTEDGTR--RLTGDNFDW
ARO1_SCHPO ANVTIPYKLSVMK--FMDELSDEARFFGAVNTII---------PIRIGDKLVLRGDNTDW
ARO1_PNECA ASVTIPLKTNISI--LLDEISDHAALIGSVNTIT---------RTYNNGQYILKGENTDW
ARO1_CANAL LAITMPLKLDIMK--FATKLSDAAETIGAVNTLIP------------IEGGYF-GDNTDW
ARO1_YEAST AAVTIPLKLDIMQ--YMDELTDAAKVIGAVNTVIP------------LGNKKFKGDNTDW
ARO1_YARLI ISVTIPLKQDIIP--FLDEVSPLAQQIGAVNTIIP------------GPNGTLKGDNTDI
ARO1_COPC7 ASVTIPFKVDVIE--LLDELTESAKEIGAVNTIIPVHRSSINAQGQEETTRVLVGDNTDW
ARO1_CRYNJ ASVTIPLKLDIIP--HLDSVSEDAKIIGAVNTVIP--------RGGK-----LHGENTDW
ARO1_USTMA ASVTIPHKLNIIK--LLDEVTDEAKTIGAVNTIIPI-------RDAQGVVTSLVGDNTDW
E3KTD2_PUCGT ASVTIPLKVEIIK--YLDQLTPDAQAVGAVNTIVPVS--------QRNGKIKLLGANTDW
F4PAP8_BATDJ ASVTIPLKIDVIQSGIATRICSAAKQIGAVNTLHMQA------------DGEIVGHNTDW
I1CAL1_RHIO9 ASVTIPHKVSVMK--YLDEVTENAKMIGAVNTVFVRE-----TVVNGEKKRQFIGENTDY
I7MKQ2_TETTS ASITMPFKLEVSK--YVDHVIGDAQLIGIDSPVIN---------TIVKLNSKIYGFNTDW
:*:* * : : .* ..: * * *
D0NXA2_PHYIT LGILRPITKRLATLSVKK-----PAHELTALVVGAGGTSMAASYAMRQLGV-GKLFVFNR
H3GHV1_PHYRM LGILRPISKRLATLSVRK-----PAHELTALVVGAGGTSMAASYAMRQLGV-GKLFIFNR
A9V1N3_MONBE LGILAALRDAGA-----------PSAPRAALVLGAGGTARAAVYALQQLGC-HRIVVVNR
ARO1_EMENI QGMILSLRKAGVYGPKRK------DQEQSALVVGGGGTARAAIYALHNMGY-SPIYIVGR
ARO1_ASPFU QGMVQCLRNAGAYGA---------DGSASALVVGGGGTSRAAIYALHQMGF-SPIYIVGR
ARO1_AJECG QGMVRCLSDAGAYAAATP------TTASAGLVIGGGGTARAAIFALQNMGY-SPIYVLGR
ARO1_PHANO LGMILILRNTGAHGV------------GAGLVIGGGGTSRAAIYALKEMGY-GPIYLLGR
ARO1_FUSV7 RGMVHALRDEGVEEQADS------ETKGAAMVVGSGGTTRAAIFALHSLGF-GPIYIAAR
I1RK93_GIBZE RGMVHALRHAGIQGQ-DT------DNKGAAMVVGSGGTTRAAIFALHSLGF-GPIYIAAR
ARO1_NEUCR MGMVYALRNAGVVKC-TK------ESPTAGMVVGAGGTTRAAVHALHDLGF-APIYVVAR
ARO1_SCLS1 LGMTHSLMSASHTPS-PV------DSPSPALVIGAGGTARAAIYALHSLGH-SPIYMVAR
D5G8D9_TUBMM VGIQNSLRIGGATEP-EG------HSTATALVIGAGGTSRAAVYALHMMGY-GRIYVVNR
ARO1_SCHPO RGIYDTFAN--ALD-GVS------LRDTNGLVIGAGGTSRAAIYSLHRLGV-SRIYLLNR
ARO1_PNECA QGIIKAIKN--FNKFEKS------FENFSGFIIGAGGASRAAIYALLSLGI-SPIYLINR
ARO1_CANAL VGISNSFIRAGVPP----------KSSSNGLVVGAGGTSRAAIYALHQMGC-AKIYLVNR
ARO1_YEAST LGIRNALINNGVPEY---------VGHTAGLVIGAGGTSRAALYALHSLGC-KKIFIINR
ARO1_YARLI LGLVNALTRFGANS----------LDKKTALIVGAGGTSLAAVHGLRSLGF-AKILIANR
ARO1_COPC7 VGIRVCITQRVSEGELRN-------ENTSGLVIGAGGTARAAIYALQDLGV-PVIYLFNR
ARO1_CRYNJ QAIHQAAAQNLDADALSY-------GSSTALVIGAGGTCRAAIYAMHKLRF-KTIYLFNR
ARO1_USTMA IAIETLARRSLRTVHLAD-------PNLTGLVIGAGGSARAALFALYRLGV-KRILLFNR
E3KTD2_PUCGT EAIKTKIEANLPAQQALGLITPSQLVRAAGVVIGAGGTARAAVYALHSLGY-EQIYIHNR
F4PAP8_BATDJ IGIKQCIQRHLGVSCSRK---------VVGIVLGAGGTARAACYALSQISYIQQVRVWNR
I1CAL1_RHIO9 LGMKHRIQALMMDPNNPP---------EEGLVIGAGGTARAALYTMQKMGI-QKIYLWNR
I7MKQ2_TETTS YGILKPLKKQLSLNEHYMQ-----SKQKFALVIGAGATTLTMVYCLNMLGF--QTLIYNR
.: ..::*.*.: : . : : : *
D0NXA2_PHYIT TLNKAQAVAARFEAEALSELTPETLA-------------RVDVVVGTIPAQAGFQLP---
H3GHV1_PHYRM TLEKAQAVAARFDAEALSELTPETLA-------------QVDVVVGTIPAQAGFQLP---
A9V1N3_MONBE TAERALALAEQFRVEHAADLMASTAY-------------TYDIVVSTVAATANLTVP---
ARO1_EMENI TPSKLENMVSTFPSSYNIRIVESPS----------SFESVPHVAIGTIPADQPIDPT---
ARO1_ASPFU NPAKLESMVSTFPTSYNIQIVEGNE----------KLEHVPHVAIGTIPADRPIDPG---
ARO1_AJECG SPDKLSSMTSTFHTDHDIRILEDVK----------ALESLPTVAIGTIPGDKPIEPH---
ARO1_PHANO NAHKIEALKSDFPSSYNLQVITSPEQ-VS------SLDAMPTVAIGTVPADQPLDPT---
ARO1_FUSV7 NQAKVDALAADFPAEYQLQGLSQPSD-AD------KVSSNLNVVISTIPADRPIDPS---
I1RK93_GIBZE NQEKADAIAADFPKEYQLEGLSRASD-AE------KVSENLKVVISTIPADRPIDPT---
ARO1_NEUCR NADRVKALAESFPAEYDIRSLSTPEEVAA------ESTAQPSVVISTIPADKPIDQS---
ARO1_SCLS1 TPSKLDTLINSFPSSFNIIPLPSTTS-AT------ELTTPPAVAISTIPADRPIESN---
D5G8D9_TUBMM TPENLKSLVEAFPKEYNLMAINSLAE-AK------SVEVKPITAVCTVPADKPIDDA---
ARO1_SCHPO TLANSYRVQDVFPPDYNIHIIDSDNIPSEE-----LSSVTLSAVVSTIPADIELPEK---
ARO1_PNECA SKDKLNKLYHFFNTNHIIPITEYHELNN--------INFDIRIGISTIPTDNPIDPS---
ARO1_CANAL TAAKLEELVKSFPKDYNLEIVETEQQADK-------ASK-VSLAVSCIPADKPLDGE---
ARO1_YEAST TTSKLKPLIESLPSEFNIIGIESTKSIEE-------IKEHVGVAVSCVPADKPLDDE---
ARO1_YARLI TLSK----AEAIADKFDNVEAVTLDSFVA-------NKYTPSVIVSCVPATTFSMLD---
ARO1_COPC7 TKEKAEDLAKAFVGGADKKWNGQLVVLDKLGGGWGDVGVAPRVIVSTVPASATALPSAST
ARO1_CRYNJ TPENAAKVKASFPESYNIAVVTSLSSLPE----------APVVVVSTVPGNSLTL-----
ARO1_USTMA TLANAEKLAREVPPEWNVSVLTSLDEVAQLSAD-----QSPSVVVSNIPAEGSTL-----
E3KTD2_PUCGT TRSKAEEVAKAFPSYFGIRVIDSLGFLCSGEEG----VWQPSAIVSAVPAQATRLSD---
F4PAP8_BATDJ TVHKAADMAKEFKYVAVEELKDLVPIAEPMEDE-----QPLYAIVGTIPSTAQDA-----
I1CAL1_RHIO9 TSSKAYDLQKAFKGFIEIEVIESLEN----------SKIGPGVIISTVPADSGIEIP---
I7MKQ2_TETTS TYQKIEKFIGRNGVIKGFSSIDDLVLYLKQN-----LHVQLSVIASTVPGKAEIDFR---
. . :.
D0NXA2_PHYIT ----------------DHLVAARADG-------SKVVVLDAAYMPPVTPMLAHAHAAG--
H3GHV1_PHYRM ----------------DHLVAPRADG-------SKVVVLDAAYMPPITPMLAHAHASG--
A9V1N3_MONBE ----------------EVLLTA-----------SRPVVLDAAYIPYKTALILQAEAAG--
ARO1_EMENI -------MRETLCHMFERAQEADAEAVKAIE-HAPRILLEMAYKPQVTALMRLASDS---
ARO1_ASPFU -------MREILCHMFERAQEADADASRTIE-GSPRVLLEMAYKPRVTALMQLAVDA---
ARO1_AJECG -------MREILCRLFDLCEKANSDTEQARGVSTKRILLEMAYKPSVTSLMQLASDS---
ARO1_PHANO -------IRETLCAFFEKAKDVKTER------GEERILLEMAYKPPVTALIQLSQDA---
ARO1_FUSV7 -------LQELVGALLSRPAVGTER----------RVLLEMAYKPSHTPIMQLADEAG--
I1RK93_GIBZE -------LQELVGAVLSRPAPAGER----------RVLLEMAYKPSHTPIMQLADDAG--
ARO1_NEUCR -------MREVIVASLRHPSVADGK----------HVLLEMAYTPRHTPLMQLAEDA---
ARO1_SCLS1 -------MRETLAVLLRHEKKDEGKQ---------RTLLEMAYKPSQTPLMRMAEDA---
D5G8D9_TUBMM -------LKVILWELLAGGAC-------------AGVLTEMAYKPTVTEVMTLAEGA---
ARO1_SCHPO -------VASVIKAL--LANKADGG-----------VFLDMAYKPLHTPLMAVASDL---
ARO1_PNECA -------VLEIAKIFFNLKRKSSEG-----------IFLDMAYGSNTTDLTIIAKAC---
ARO1_CANAL -------VLKKIERILSNGSEQSAGF--------KPTLLEASYKPRVTPIMKLTEEQY--
ARO1_YEAST -------LLSKLERFLVKGAH--AAF--------VPTLLEAAYKPSVTPVMTISQDKY--
ARO1_YARLI -------ESNKLVSAALAASP-------------KGLVLEAAYSAEATPLLKQVMDVE--
ARO1_COPC7 AAIAGQVDKSTNQIVLPADVFAYTSGS--------AVVVDMAYKPAETPLLKLAKELKEE
ARO1_CRYNJ -------DTFSQGIYLPSEVLSRPKG----------VAIDLAYKPHMTALLHAAE--KKE
ARO1_USTMA -------DASSRGLIHLPTCMLRNPAG--------GVVIDMSYKPHYTSLLQLAQQVNTN
E3KTD2_PUCGT -------DPPSDRLEIPRGLFDRPGG---------GVVIEMSYSLGKDSPLLRAVQDLVG
F4PAP8_BATDJ ---------------LDLDSLFKDGVG--------GVVVEMAYRPRQTKLIMAAQHANQK
I1CAL1_RHIO9 -------------AHLYGGIK--------------GIICDMAYKPRRTKLLLQADRKG--
I7MKQ2_TETTS ------------------DIMFKYKP----------TIFEASYIPKETSLVQYAKNSG--
: :*
D0NXA2_PHYIT ----------------GVLCIQGYEMLYEQGIEQ----------------FYRWHKATQV
H3GHV1_PHYRM ----------------GALCIQGYEMLYEQGIEQ----------------FYRWHKATQV
A9V1N3_MONBE ----------------CRVA-HGIDMLLHQGLAQ----------------AQLFCGGTTL
ARO1_EMENI ----------------GWKTIPGLEVLVGQGWYQ----------------FKYWTG-ISP
ARO1_ASPFU ----------------GWTTIPGLEALIGQGVHQVGLIDLLQMDITDGVQFQHWTG-IRP
ARO1_AJECG ----------------GWTVLPGLEALVAQGVYQ----------------CEYWTN-ITP
ARO1_PHANO ----------------GWKTVNGLEVLVGQGVHQ----------------FEYWTG-VKP
ARO1_FUSV7 ----------------NWTTVPGLEVLASQGWYQ----------------FELWTG-ITP
I1RK93_GIBZE ----------------NWTTIPGLEVLSSQGWYQ----------------FELWTG-ITP
ARO1_NEUCR ----------------HWQTIPGLEVLAAQGWYQ----------------FQLWTG-ITP
ARO1_SCLS1 ----------------GWVAIPGLEVLSAQGWYQ----------------FQKWTS-IQP
D5G8D9_TUBMM ----------------GWRVVPGLEGLVGQGVAQ----------------FEVFTGGIVP
ARO1_SCHPO ----------------EWKCCNGLEALVRQGLAS----------------FHLWTGMTAP
ARO1_PNECA ----------------NWKIIHGLEILLEQGSEQ----------------FLLWTETYIP
ARO1_CANAL ----------------KWKVIPGVEMLVNQGDRQ----------------FKLHTGFTAP
ARO1_YEAST ----------------QWHVVPGSQMLVHQGVAQ----------------FEKWTGFKGP
ARO1_YARLI ----------------GWEFISGLYMLTEQGFEQ----------------FRLWTGIPAP
ARO1_COPC7 GN---------------WACVQGLEVLLEQGYIQ----------------FEKWTGRRCP
ARO1_CRYNJ G----------------WKVVPGVEILCLQGFKQ----------------FEEWTGKRAP
ARO1_USTMA HELAIGTNATKAPTRKLWAAVPGITILLEQGCHQ----------------FHRWTGREAP
E3KTD2_PUCGT -----------------WKSVDGLELLVEQGARQ----------------FQLWTGKHLS
F4PAP8_BATDJ HSST-------------FACVEGIDVLIEQGYEQ----------------FQLWTGCHPP
I1CAL1_RHIO9 -----------------WSCVEGIEVLISQGIAQ----------------FEIWTGKKAP
I7MKQ2_TETTS ----------------CYTFVYGLDMLLYQAYLQN----------------LIFTGKKVF
* * *. .
D0NXA2_PHYIT WTVNEE------------------------AIKEACRQHVPVDQRLSEA-----------
H3GHV1_PHYRM WVVNEE------------------------AIKEACRQHVPIDQRLSQA-----------
A9V1N3_MONBE SSELQK------------------------KVWARVHACYQAMLAMEPAERVMPNI----
ARO1_EMENI LYESAR-----------------------ACSSPLI------------------------
ARO1_ASPFU LYERAR-----------------------VCCDILLSGRTMLTCS---------------
ARO1_AJECG VYEYAR-----------------------NAVMGVSPSEDIL------------------
ARO1_PHANO LYSVARLQLLSHHRLPRYSHLNSNYSNHSAHCSTVPAKTSILPYHRPLYTLAFVIKLHGL
ARO1_FUSV7 LYRDAR-----------------------SAVLGL-------------------------
I1RK93_GIBZE LYKDAR-----------------------AAVLGE-------------------------
ARO1_NEUCR IYTDAQ-----------------------AAVMGN-------------------------
ARO1_SCLS1 LYVDAR-----------------------AAVMGDSTA----------------------
D5G8D9_TUBMM EYGAAR-----------------------AAVLGV-------------------------
ARO1_SCHPO FDAVYQ------------------------KVIE--------------------------
ARO1_PNECA YNQVKY------------------------AILGPNK-----------------------
ARO1_CANAL YEIIHR------------------------AVVEE-------------------------
ARO1_YEAST FKAIFD------------------------AVTKE-------------------------
ARO1_YARLI KEVGEK------------------------AVLGN-------------------------
ARO1_COPC7 KEQVST------------------------RVWEKYGEV---------------------
ARO1_CRYNJ QKKMRK------------------------AVLDKYFA----------------------
ARO1_USTMA RAQIEA------------------------AAWDVYLQRC--------------------
E3KTD2_PUCGT MKIVSQ------------------------AVYQEASSD---------------------
F4PAP8_BATDJ HAVMSE------------------------AVYTNYR-----------------------
I1CAL1_RHIO9 NHRIEE------------------------EVLRRYEL----------------------
I7MKQ2_TETTS RKQIQD------------------------STQNYYKKLHCTQD----------------
D0NXA2_PHYIT --------------------------
H3GHV1_PHYRM --------------------------
A9V1N3_MONBE --------------------------
ARO1_EMENI --------------------------
ARO1_ASPFU --------------------------
ARO1_AJECG --------------------------
ARO1_PHANO VAHCRTLRDAFSFSVFLTYSWSLGDW
ARO1_FUSV7 --------------------------
I1RK93_GIBZE --------------------------
ARO1_NEUCR --------------------------
ARO1_SCLS1 --------------------------
D5G8D9_TUBMM --------------------------
ARO1_SCHPO --------------------------
ARO1_PNECA --------------------------
ARO1_CANAL --------------------------
ARO1_YEAST --------------------------
ARO1_YARLI --------------------------
ARO1_COPC7 --------------------------
ARO1_CRYNJ --------------------------
ARO1_USTMA --------------------------
E3KTD2_PUCGT --------------------------
F4PAP8_BATDJ --------------------------
I1CAL1_RHIO9 --------------------------
I7MKQ2_TETTS --------------------------