CLUSTAL format seed alignment for MF_04099
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Features found in the protein:- The following colors are used to highlight features:
- blue indicates SIGNAL, PROPEP, TRANSMEM, DOMAIN, ZN_FING, REPEAT,
DNA_BIND and CA_BIND.
- magenta is used to display DISULFID, THIOLEST and THIOETH.
- red is used for all other features, such as INIT_MET, ACTIVE SITE,
METAL,BINDING, NP_BIND, SITE, REGION, etc.
- The ID of the sequence used as the template for feature propagation is
underlined.
- A '<' at the beginning of a sequence or '>' at the end indicate that
the protein is fused with another domain either at the N- or C-terminus.
_____________________________________________________________________________
SPIKE_BCHK9 ------MLLILVLGVSLAAASRPECFN------------------PRFTLTP--------
SPIKE_SARS ----MFIFLLFLTLTSGSDLDRCTTFD-------DVQ-------APNYTQHT--------
SPIKE_BCHK3 ----MKILIFAFLANLAKAQEGCGIIS-------RKP-------QPKMAQVS--------
SPIKE_BC279 ----MKVLIFALLFSLAKAQEGCGIIS-------RKP-------QPKMEKVS--------
SPIKE_BCRP3 ----MKILILAFLASLAKAQEGCGIIS-------RKP-------QPKMAQVS--------
SPIKE_CVHN1 -----MLLIIFILPTTLAVIGDFNCTN-FAINDLNTT-------VPRISEYV--------
SPIKE_CVHN5 ----MFLIIFI-LPTTLAVIGDFNCTN-SFINDYNKT-------IPRISEDV--------
SPIKE_CVHN2 ----MFLIIFI-LPTTLAVIGDFNCTN-SFINDYNKT-------IPRISEDV--------
SPIKE_CVRSD ----MLFVFLTLLPSCLGYIGDFRCINLVNTRISNAR-------APSVSTEV--------
SPIKE_CVMA5 ----MLFVFILFLPSCLGYIGDFRCIQLVNSNGANVS-------APSISTET--------
SPIKE_CVMJC ----MLFVFILFLPSCLGYIGDFRCIQTVNYNGNNAS-------APSISTEA--------
SPIKE_CVM4 ----MLFVFILLLPSCLGYIGDFRCIQTVNYNGNNAS-------APSISTEA--------
SPIKE_CVMJH ----MLFVFILLLPSCLGYIGDFRCIQTVNYNGNNAS-------APSISTEA--------
SPIKE_CVP67 ----MFFILLISLPSAFAVIGDLKCTT-SLINDVDTG-------VPSISSEV--------
SPIKE_CVPIA ----MFFILLITLPSVFAVIGDLKCNT-SSINDVDTG-------VPSISSEV--------
SPIKE_CVHOC ----MFLILLISLPTAFAVIGDLKCTS-DNINDKDTG-------PPPISTDT--------
SPIKE_CVBLS ----MFLILLISLPTAFAVIGDLKCTT-VSINDVDTG-------VPSISTDT--------
SPIKE_CVBOK ----MFLILLISLPTAFAVIGDLKCTT-VSINDVDTG-------VPSISTDT--------
SPIKE_CVBEN ----MFLILLISLPTAFAVIGDLKCTT-VSINDVDTG-------VPSISTDT--------
SPIKE_CVBLU ----MFLILLISLPTAFAVIGDLKCTT-VSINDVDTG-------VPSISTDT--------
SPIKE_CVBM ----MFLILLISLPMAFAVIGDLKCTT-VSINDVDTG-------APSISTDI--------
SPIKE_CVBQ ----MFLILLISLPMAFAVIGDLKCTT-VSINDVDTG-------APSISTDI--------
SPIKE_CVBL9 ----MFLILLISLPMAFAVIGDLKCTT-VSINDVDTG-------APSISTDI--------
SPIKE_CVBV ----MFLILLISLPMAFAVIGDLKCTT-VSINDVDTG-------APSISTDT--------
SPIKE_CVBF ----MFLILLISLPMALAVIGDLKCTT-VSINDVDTG-------VPSISTDT--------
SPIKE_CVBLY ----MFLILLISLPMALAVIGDLKCTT-VSINDVDTG-------VPSVSTDT--------
SPIKE_CVEMC MIHSVFLLMFLLTPTESYVDVGPDSVK-----------------SACIEVDI-QQTFFDK
SPIKE_BCHK5 -----MIRSVLVLMCSLTFIGNLTRGQSVDMGHNGTGSCLDSQVQPDYFESV------HT
SPIKE_BC133 ----M-TRLMCLLMSLSIFVRGFDSQF-VDMSPASNA-------SECLESQVDAAAFSKL
SPIKE_BCHK4 ----M-TLLMCLLMSLLIFVRGCDSQF-VDMSPASNT-------SECLESQVDAAAFSKL
.
SPIKE_BCHK9 ---------LNHTLNYTSIKAKVSNVLLPDPYI-AYSGQTLRQNLFMADMSN-----TIL
SPIKE_SARS --------SSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHT-----------
SPIKE_BCHK3 --------SSRRGVYYNDDIFRSDVLHLTQDYFLPFDSNLTQYFSLNVDSD------RYT
SPIKE_BC279 --------SSRRGVYYNDDIFRSDVLHLTQDYFLPFDSNLTQYFSLNIDSN------KYT
SPIKE_BCRP3 --------SSRRGVYYNDDIFRSNVLHLTQDYFLPFDSNLTQYFSLNVDSD------RFT
SPIKE_CVHN1 -----VDVSYGLGTYYILDRVYLNTTILFTGYF-PKSGANFRDLSLKGTTYL-----STL
SPIKE_CVHN5 -----VDVSLGLGTYYVLNRVYLNTTLLFTGYF-PKSGANFRDLALKGSIYL-----STL
SPIKE_CVHN2 -----VDVSLGLGTYYVLNRVYLNTTLLFTGYF-PKSGANFRDLALKGSKYL-----STL
SPIKE_CVRSD -----VDVSKGLGTYYVLDRVYLNATLLLTGYY-PVDGSMYRNMALMGTNTL-----SLN
SPIKE_CVMA5 -----VEVSQGLGTYYVLDRVYLNATLLLTGYY-PVDGSKFRNLALRGTNSV-----SLS
SPIKE_CVMJC -----VDVSKGLGTYYVLDRVYLNATLLLTGYY-PVDGSNYRNLALTGTNTL-----SLT
SPIKE_CVM4 -----VDVSKGLGTYYVLDRVYLNATLLLTGYY-PVDGSNYRNLALTGTNTL-----SLT
SPIKE_CVMJH -----VDVSKGRGTYYVLDRVYLNATLLLTGYY-PVDGSNYRNLALTGTNTL-----SLT
SPIKE_CVP67 -----VDVTNGLGTFYVLDRVYLNTTLLLNGYY-PISGATFRNMALKGTRLL-----STL
SPIKE_CVPIA -----VDVTNGLGTFYVLDRVYLNTTLLLNGYY-PISGATFRNVALKGTRLL-----STL
SPIKE_CVHOC -----VDVTNGLGTYYVLDRVYLNTTLFLNGYY-PTSGSTYRNMALKGSVLL-----SRL
SPIKE_CVBLS -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----STL
SPIKE_CVBOK -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----STL
SPIKE_CVBEN -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----STL
SPIKE_CVBLU -----VDVTKGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----STL
SPIKE_CVBM -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----SRL
SPIKE_CVBQ -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----SRL
SPIKE_CVBL9 -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----SRL
SPIKE_CVBV -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----SRL
SPIKE_CVBF -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----STL
SPIKE_CVBLY -----VDVTNGLGTYYVLDRVYLNTTLLLNGYY-PTSGSTYRNMALKGTLLL-----STL
SPIKE_CVEMC TWPRPIDVSKADGIIYPQGRTYSNITITYQGLF-PYQGDHGDMYVYSAGHATGTT--PQK
SPIKE_BCHK5 TWPMPIDTSKAEGVIYPNGKSYSNITLTYTGLY-PKANDLGKQYLFSDGHSA--PGRLNN
SPIKE_BC133 VWPYPIDPAKVDGIIYPLGRTYSNITLEYTGLF-PLQGDLGMQYLYSVSHAVGNDGDPTK
SPIKE_BCHK4 MWPYPIDPSKVDGIIYPLGRTYSNITLAYTGLF-PLQGDLGSQYLYSVSHAVGHDGDPTK
* . . .
SPIKE_BCHK9 YPVTPP---ANGANGGFIYNTSIIPVSAGLFVNTWMYRQPASSRAYCQEPFGVAFGDTFE
SPIKE_SARS -FGNP----VIPFKDGIYFAAT----EKSNVVRGWVF------------------GSTMN
SPIKE_BCHK3 YFDNP----ILDFGDGVYFAAT----EKSNVIRGWIF------------------GSSFD
SPIKE_BC279 YFDNP----ILDFGDGVYFAAT----EKSNVIRGWIF------------------GSSFD
SPIKE_BCRP3 YFDNP----ILDFGDGVYFAAT----EKSNVIRGWIF------------------GSTFD
SPIKE_CVHN1 WYQKPF---LSDFNNGIFSRVK----NTKLYVNKTLYSE---------FS-TIVIGSVFI
SPIKE_CVHN5 WYKPPF---LSDFNNGIFSKVK----NTKLYVNNTLYSE---------FS-TIVIGSVFV
SPIKE_CVHN2 WYKPPF---LSDFNNGIFSKVK----NTKLYVNNTLYSE---------FS-TIVIGSVFV
SPIKE_CVRSD WFEPPF---LSEFNDGIYAKVK----NLKASLPIGSASY---------FP-TIIIGSNFV
SPIKE_CVMA5 WFQPPY---LNQFNDGIFAKVQ----NLKTSTPSGATAY---------FP-TIVIGSLFG
SPIKE_CVMJC WFKPPF---LSEFNDGIFAKVQ----NLKTNTPTGATSY---------FP-TIVIGSLFG
SPIKE_CVM4 WFKPPF---LSEFNDGIFAKVQ----NLKTNTPTGATSY---------FP-TIVIGSLFG
SPIKE_CVMJH WFKPPF---LSEFNDGIFAKVQ----NLKTNTPTGATSY---------FP-TIVIGSLFG
SPIKE_CVP67 WFKPPF---LSPFNDGIFAKVK----NSRFSKDGVIYSE---------FP-AITIGSTFV
SPIKE_CVPIA WFKPPF---LSPFNDGIFAKVK----NSRFSKHGVIYSE---------FP-AITIGSTFV
SPIKE_CVHOC WFKPPF---LSDFINGIFAKVK----NTKVIKDRVMYSE---------FP-AITIGSTFV
SPIKE_CVBLS WFKPPF---LSDFTNGIFAKVK----NTKVIKDGVKYSE---------FP-AITIGSTFV
SPIKE_CVBOK WFKPPF---LSDFTNGIFAKVK----NTKVIKDGVKYSE---------FP-AITIGSTFV
SPIKE_CVBEN WFKPPF---LSDFTNGIFAKVK----NTKVIKDGVMYSE---------FP-AITIGSTFV
SPIKE_CVBLU WFKPPF---LSDFTNGIFAKVK----NTKVIKDGVMYSE---------FP-AITIGSTFV
SPIKE_CVBM WFKPPF---LSDFINGIFAKVK----NTKVIKKGVMYSE---------FP-AITIGSTFV
SPIKE_CVBQ WFKPPF---LSDFINGIFAKVK----NTKVIKKGVMYSE---------FP-AITIGSTFV
SPIKE_CVBL9 WFKPPF---LSDFINGIFAKVK----NTKVIKKGVMYSE---------FP-AITIGSTFV
SPIKE_CVBV WFKPPF---LSDFINGIFAKVK----NTKVIKKGVMYSE---------FP-AITIGSTFV
SPIKE_CVBF WFKPPF---LSDFINGIFAKVK----NTKVIKHGVMYSE---------FP-AITIGSTFV
SPIKE_CVBLY WFKPPF---LSDFINGIFAKVK----NTKVIKNGVMYSE---------FP-AITIGSTFV
SPIKE_CVEMC LFVANYSQDVKQFANGFVVRIG----AAANSTGTVIISPSTSATIRKIYP-AFMLGSSVG
SPIKE_BCHK5 LFVSNYSSQVESFDDGFVVRIG----AAANKTGTTVISQSTFKPIKKIYP-AFLLGHSVG
SPIKE_BC133 AYISNYSLLVNDFDNGFVVRIG----AAANSTGTIVISPSVNTKIKKAYP-AFILGSSLT
SPIKE_BCHK4 AYISNYSLLVNDFDNGFVVRIG----AAANSTGTIVISPSVNTKIKKAYP-AFILGSSLT
.*. * .
SPIKE_BCHK9 NDRI---------AILIMAPDNLGSWSAVAPRNQTNIYLLVC----------------SN
SPIKE_SARS NKS----------QSVIIINN------------STNVVIRAC-----------------N
SPIKE_BCHK3 NTT----------QSAVIVNN------------STHIIIRVC-----------------N
SPIKE_BC279 NTT----------QSAIIVNN------------STHIIIRVC-----------------N
SPIKE_BCRP3 NTT----------QSAVIVNN------------STHIIIRVC-----------------N
SPIKE_CVHN1 NNS----------YTIVVQPH------------NGVLEITAC-----------------Q
SPIKE_CVHN5 NTS----------YTIVVQPH------------NGILEITAC-----------------Q
SPIKE_CVHN2 NTS----------YTIVVQPH------------NGILEITAC-----------------Q
SPIKE_CVRSD NTS----------YTVVLEPY------------NGIIMASIC-----------------Q
SPIKE_CVMA5 YTS----------YTVVIEPY------------NGVIMASVC-----------------Q
SPIKE_CVMJC NTS----------YTVVLEPY------------NNIIMASVC-----------------T
SPIKE_CVM4 NTS----------YTVVLEPY------------NNIIMASVC-----------------T
SPIKE_CVMJH NTS----------YTVVLEPY------------NNIIMASVC-----------------T
SPIKE_CVP67 NTS----------YSIVVEPHTSLI----NGNLQGLLQISVC-----------------Q
SPIKE_CVPIA NTS----------YSIVVKPHTSFI----NGNLQGFLQISVC-----------------Q
SPIKE_CVHOC NTS----------YSVVVQPRTINSTQDGDNKLQGLLEVSVC-----------------Q
SPIKE_CVBLS NTS----------YSVVVQPHTTNL----DNKLQGLLEISVC-----------------Q
SPIKE_CVBOK NTS----------YSVVVQPHTTNL----DNKLQGLLEISVC-----------------Q
SPIKE_CVBEN NTS----------YSVVVQPHTTIL----GNKLQGFLEISVC-----------------Q
SPIKE_CVBLU NTS----------YSVVVQPHTTIL----GNKLQGFLEISVC-----------------Q
SPIKE_CVBM NTS----------YSVVVQPHTTNL----DNKLQGLLEISVC-----------------Q
SPIKE_CVBQ NTS----------YSVVVQPHTTNL----DNKLQGLLEISVC-----------------Q
SPIKE_CVBL9 NTS----------YSVVVQPHTTNL----DNKLQGLLEISVC-----------------Q
SPIKE_CVBV NTS----------YSVVVQPHTTNL----DNKLQGLLEISVC-----------------Q
SPIKE_CVBF NTS----------YSVVVQPHTTNL----DNKLQGLLEISVC-----------------Q
SPIKE_CVBLY NTS----------YSVVVQPHTTNL----DNKLQGLLEISVC-----------------Q
SPIKE_CVEMC NFSDGKMG-RFFNHTLVLLPDGC----------GTLLRAFYCILEPRSGNHCPAGNSYTS
SPIKE_BCHK5 NYTPSNRTGRYLNHTLVILPDGC----------GTILHAFYCVLHPRTQQNCAGETNFKS
SPIKE_BC133 NTSAGKPL--YANYSLTIIPDGC----------GTVLHAFYCILKPRTGNRCPSGSDYNA
SPIKE_BCHK4 NTSAGQPL--YANYSLTIIPDGC----------GTVLHAFYCILKPRTVNRCPSGTGYVS
: : *
SPIKE_BCHK9 ATLCINPGFNRWGP----AGSFIAPDALVDHSNSCFVNN---TFSVNISTSRISL----A
SPIKE_SARS FELCDNPFFAVSKP----MGTQTHTMIFDNAFN-CTFEYISDAFSLDVSEKSGNFKHLRE
SPIKE_BCHK3 FNLCKEPMYTVSR------GTQQNAWVYQSAFN-CTYDRVEKSFQLDTTPKTGNFKDLRE
SPIKE_BC279 FNLCKEPMYTVSK------GTQQSSWVYQSAFN-CTYDRVEKSFQLDTAPKTGNFKDLRE
SPIKE_BCRP3 FNLCKEPMYTVSR------GAQQSSWVYQSAFN-CTYDRVEKSFQLDTAPKTGNFKDLRE
SPIKE_CVHN1 YTMCEYP-HTICKS-K--GSSRNESWHFDKSEPLCLFKK---NFTYNVSTDWLYF-----
SPIKE_CVHN5 YTMCEYP-HTVCKS-K--GSIRNESWHIDSSEPLCLFKK---NFTYNVSADWLYF-----
SPIKE_CVHN2 YTMCEYP-HTVCKS-K--GSIRNESWHIDSSEPLCLFKK---NFTYNVSADWLYF-----
SPIKE_CVRSD YTICQLP-HTDCKP-NTGGNTLIGFWHTDLRPPVCILKR---NFTFNVNAEWLYF-----
SPIKE_CVMA5 YTICQLP-YTDCKP-NTNGNKLIGFWHTDVKPPICVLKR---NFTLNVNADAFYF-----
SPIKE_CVMJC YTICQLP-YTPCKP-NTNGNRVIGFWHTDVKPPICLLKR---NFTFNVNAPWLYF-----
SPIKE_CVM4 YTICQLP-YTPCKP-NTNGNRVIGFWHTDVKPPICLLKR---NFTFNVNAPWLYF-----
SPIKE_CVMJH YTICQLP-YTPCKP-NTNGNRVIGFWHTDVKPPICLLKR---NFTFNVNAPWLYF-----
SPIKE_CVP67 YTMCEYP-HTICHP-NL-GNQRIELWHYDTDVVSCLYRR---NFTYDVNADYLYF-----
SPIKE_CVPIA YTMCEYP-QTICHP-NL-GNQRIELWHHDTDVVSCLYRR---NFTYDVNADYLYF-----
SPIKE_CVHOC YNMCEYP-QTICHP-NL-GNHRKELWHLDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBLS YTMCEYP-NTICNP-NL-GNQRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBOK YTMCEYP-NTICNP-NL-GNQRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBEN YTMCEYP-NTICNP-NL-GNQRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBLU YTMCEYP-NTICNP-NL-GNRRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBM YTMCEYP-HTICHP-NL-GNKRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBQ YTMCEYP-HTICHP-KL-GNKRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBL9 YTMCEYP-HTICHP-NL-GNKRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBV YTMCEYP-HTICHP-NL-GNQRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBF YTMCEYP-NTICHP-NL-GNRRVELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVBLY YTMCEYP-HTICHP-NL-GNRRIELWHWDTGVVSCLYKR---NFTYDVNADYLYF-----
SPIKE_CVEMC FATYHTP-ATDCSDGNYNRNASLNSFKEYFNLRNCTFMY---TYNITEDEILEWF-----
SPIKE_BCHK5 LSLWDTP-ASDCVSGSYNQEATLGAFKVYFDLINCTFRY---NYTITEDENAEWF-----
SPIKE_BC133 YFIYETI-HSDCQS-TINRNASLNSFKSFFDLVNCTFFN---SWDITADETKEWF-----
SPIKE_BCHK4 YFIYETV-HNDCQS-TINRNASLNSFKSFFDLVNCTFFN---SWDITADETKEWF-----
* : :
SPIKE_BCHK9 FLFKDGDLLIYHSGWLPTSNFEHGFSRGSHPMTYFMSLPVGGNLPRAQFFQSIVRSNAID
SPIKE_SARS FVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDI
SPIKE_BCHK3 YVFKNRDGFLSVYQTYTAVNLPRGLPTGFSVLKPILKLPFGINITSYRVVMAMFSQTTSN
SPIKE_BC279 YVFKNRDGFLSVYQTYTAVNLPRGFPAGFSVLRPILKLPFGINITSYRVVMTMFSQFNSN
SPIKE_BCRP3 YVFKNRDGFLSVYQTYTAVNLPRGLPIGFSVLRPILKLPFGINITSYRVVMAMFSQTTSN
SPIKE_CVHN1 HFYQERGTFYAYYA-------DSGMPTTF-----LFSLYLGTLLSHYYVLPLTCNAISSN
SPIKE_CVHN5 HFYQERGVFYAYYA-------DVGMPTTF-----LFSLYLGTILSHYYVMPLTCNAISSN
SPIKE_CVHN2 HFYQERGVFYAYYA-------DVGMPTTF-----LFSLYLGTILSHYYVMPLTCKAISSN
SPIKE_CVRSD HFYQQGGTFYAYYA-------DVSSATTF-----LFSSYIGAVLTQYFVLPYMCSPTTSG
SPIKE_CVMA5 HFYQHGGTFYAYYA-------DKPSATTF-----LFSVYIGDILTQYYVLPFICNPTAGS
SPIKE_CVMJC HFYQQGGTFYAYYA-------DKPSATTF-----LFSVYIGDILTQYFVLPFICTPTAGS
SPIKE_CVM4 HFYQQGGTFYAYYA-------DKPSATTF-----LFSVYIGDILTQYFVLPFICTPTAGS
SPIKE_CVMJH HFYQQGGTFYAYYA-------DKPSATTF-----LFSVYIGDILTQYFVLPFICTPTAGS
SPIKE_CVP67 HFYQEGGTFYAYFT-------DTGFVTKF-----LFKLYLGTVLSHYYVMPLTCNSA---
SPIKE_CVPIA HFYQEGGTFYAYFT-------DTGFVTKF-----LFKLYLGTVLSHYYVMPLTCDSA---
SPIKE_CVHOC HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGMALSHYYVMPLTCNSK---
SPIKE_CVBLS HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVMPLTCNSA---
SPIKE_CVBOK HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVMPLTCNSA---
SPIKE_CVBEN HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVMPLTCNSA---
SPIKE_CVBLU HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVMPLTCNSA---
SPIKE_CVBM HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVLPLTCSSA---
SPIKE_CVBQ HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVLPLTCSSA---
SPIKE_CVBL9 HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVLPLTCNSA---
SPIKE_CVBV HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVLPLTCYSA---
SPIKE_CVBF HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVMPLTCNSA---
SPIKE_CVBLY HFYQEGGTFYAYFT-------DTGVVTKF-----LFNVYLGTVLSHYYVMPLTCNSA---
SPIKE_CVEMC GITQTAQGVHLFSS-------RYVDLYGGNMFQ-FATLPVYDTIKYYSIIPHSIRSIQSD
SPIKE_BCHK5 GITQDTQGVHLYSS-------RKENVFRNNMFH-FATLPVYQKILYYTVIPRSIRSPFND
SPIKE_BC133 GITQDTQGVHLHSS-------RKGDLYGGNMFR-FATLPVYEGIKYYTVIPRSFRSKANK
SPIKE_BCHK4 GITQDTQGVHLYSS-------RKGDLYGGNMFR-FATLPVYEGIKYYTVIPRSFRSKANK
. : . : . . : .
SPIKE_BCHK9 KGDGMCTNFDVNLHVAHLINRDLLVSYFNNGSVANAADCADSAAEELYCVTGSFDPPTGV
SPIKE_SARS WG-----TSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGI
SPIKE_BCHK3 FL-----PESAAYYVGNLKYSTFMLRFNENGTITDAVDCSQNPLAELKCTIKNFNVDKGI
SPIKE_BC279 FL-----PESAAYYVGNLKYTTFMLSFNENGTITDAVDCSQNPLAELKCTIKNFNVSKGI
SPIKE_BCRP3 FL-----PESAAYYVGNLKYTTFMLSFNENGTITNAIDCAQNPLAELKCTIKNFNVSKGI
SPIKE_CVHN1 TD-----NETLQYWVTPLSKRQYLLKFDNRGVITNAVDCSSSFFSEIQCKTKSLLPNTGV
SPIKE_CVHN5 TD-----NETLEYWVTPLSRRQYLLNFDEHGVITNAVDCSSSFLSEIQCKTQSFAPNTGV
SPIKE_CVHN2 TD-----NETLEYWVTPLSRRQYLLNFDEHGVITNAVDCSSSFLSEIQCKTQSFAPNTGV
SPIKE_CVRSD -------VSSPQYWVTPLVKRQYLFNFNQKGIITSAVDCASSYTSEIKCKTQSMNPNTGV
SPIKE_CVMA5 -------TFAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTQSMLPSTGV
SPIKE_CVMJC -------TLLPLYWVTPLLKRQYLFNFNEKGVITSAVDCASSYISEIKCKTQSLLPSTGV
SPIKE_CVM4 -------TLLPLYWVTPLLKRQYLFNFNEKGVITSAVDCASSYISEIKCKTQSLLPSTGV
SPIKE_CVMJH -------TLAPLYWVTPLLKRQYLFNFNEKGVITSAVDCASSYISEIKCKTQSLLPSTGV
SPIKE_CVP67 --------LSLEYWVTPLTTRQFLLAFDQDGVLYHAVDCASDFMSEIMCKTSSITPPTGV
SPIKE_CVPIA --------LSLEYWVTPLTTRQFLLAFDQDGVLYHAVDCASDFMSEIMCKTSSITPPTGV
SPIKE_CVHOC --------LTLEYWVTPLTSRQYLLAFNQDGIIFNAEDCMSDFMSEIKCKTQSIAPPTGV
SPIKE_CVBLS --------LTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBOK --------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBEN --------LTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBLU --------LTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBM --------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBQ --------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBL9 --------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBV --------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBF --------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVBLY --------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGV
SPIKE_CVEMC R------KAWAAFYVYKLQPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGV
SPIKE_BCHK5 R------KAWAAFYIYKLHPLTYLLNFDVEGYITKAVDCGYDDLAQLQCSYESFEVETGV
SPIKE_BC133 R------EAWAAFYVYKLHQLTYLLDFSVDGYIRRAIDCGHDDLSQLHCSYTSFEVDTGV
SPIKE_BCHK4 R------EAWAAFYVYKLHQLTYLLDFSVDGYIRRAIDCGHDDLSQLHCSYTSFEVDTGV
: * :. : * : * ** . :: * .: .*:
SPIKE_BCHK9 YPLSRYRAQVAGFV--RVTQRGSYCT-PPYSVLQDPPQPVVWRRYMLYDCVFDFTVVVDS
SPIKE_SARS YQTSNFRVVPSGDVVRF-PNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNS
SPIKE_BCHK3 YQTSNFRVSPTQEVIRF-PNITNRCPFDKVFNATRFPNVYAWERTKISDCVADYTVLYNS
SPIKE_BC279 YQTSNFRVTPTQEVVRF-PNITNRCPFDKVFNASRFPNVYAWERTKISDCVADYTVLYNS
SPIKE_BCRP3 YQTSNFRVSPTQEVIRF-PNITNRCPFDKVFNATRFPNVYAWERTKISDCVADYTVLYNS
SPIKE_CVHN1 YDLSGFTVKPVATVHRRIPDLPD-CDIDKWLNNFNVPSPLNWERKIFSNCNFNLSTLLRL
SPIKE_CVHN5 YDLSGFTVKPVATVYRRIPNLPD-CDIDNWLNNVSVPSPLNWERRIFSNCNFNLSTLLRL
SPIKE_CVHN2 YDLSGFTVKPVATVYRRIPNLPD-CDIDNWLNNVSVPSPLNWERRIFSNCNFNLSTLLRL
SPIKE_CVRSD YDLSGYTVQPVGLVYRRVRNLPD-CKIEEWLAANTVPSPLNWERKTFQNCNFNLSSLLRF
SPIKE_CVMA5 YELSGYTVQPVGVVYRRVANLPA-CNIEEWLTARSVPSPLNWERKTFQNCNFNLSSLLRY
SPIKE_CVMJC YDLSGYTVQPVGVVYRRVPNLPD-CKIEEWLTAKSVPSPLNWERRTFQNCNFNLSSLLRY
SPIKE_CVM4 YDLSGYTVQPVGVVYRRVPNLPD-CKIEEWLTAKSVPSPLNWERRTFQNCNFNLSSLLRY
SPIKE_CVMJH YDLSGYTVQPVGVVYRRVPNLPD-CKIEEWLTAKSVPSPLNWERRTFQNCNFNLSSLLRY
SPIKE_CVP67 YELNGYTVQPVATVYRRIPDLPN-CDIEAWLNSKTVSSPLNWERKIFSNCNFNMGRLMSF
SPIKE_CVPIA YELNGYTVQPVATVYRRIPDLPN-CDIEAWLNSKTVSSPLNWERKIFSNCNFNMGRLMSF
SPIKE_CVHOC YELNGYTVQPIADVYRRKPNLPN-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBLS YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBOK YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBEN YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBLU YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBM YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBQ YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBL9 YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSCLMSF
SPIKE_CVBV YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBF YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVBLY YELNGYTVQPIADVYRRIPNLPD-CNIEAWLNDKSVPSPLNWERKTFSNCNFNMSSLMSF
SPIKE_CVEMC YSVSSFEAKPSGSVVEQ-AEGVE-CDFSPLLSGTP-PQVYNFKRLVFTNCNYNLTKLLSL
SPIKE_BCHK5 YSVSSFEASPRGEFIEQ-ATTQE-CDFTPMLTGTP-PPIYNFKRLVFTNCNYNLTKLLSL
SPIKE_BC133 YSVSSYEASATGTFIEQ-PNVTE-CDFSPMLTGVA-PQVYNFKRLVFSNCNYNLTKLLSL
SPIKE_BCHK4 YSVSSYEASATGTFIEQ-PNATE-CDFSPMLTGVA-PQVYNFKRLVFSNCNYNLTKLLSL
* . : . . * . : * : :* : :
SPIKE_BCHK9 LPTHQLQCYGVSPRRLASMCYGSVTLDVMRINETHLNNLFNRVPDTFSLYNYALPDNFYG
SPIKE_SARS TFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMG
SPIKE_BCHK3 TSFSTFKCYGVSPSKLIDLCFTSVYADTFLIRSSEVRQVAPGETGVIADYNYKLPDDFTG
SPIKE_BC279 TSFSTFKCYGVSPSKLIDLCFTSVYADTFLIRSSEVRQVAPGETGVIADYNYKLPDDFTG
SPIKE_BCRP3 TSFSTFKCYGVSPSKLIDLCFTSVYADTFLIRSSEVRQVAPGETGVIADYNYKLPDDFTG
SPIKE_CVHN1 VHTDSFSCNNFDESKIYGSCFKSIVLDKFAIPNSRRSDLQLGSSGFLQSSNYKIDTTSSS
SPIKE_CVHN5 VHVDSFSCNNLDKSKIFGSCFNSITVDKFAIPNRRRDDLQLGSSGFLQSSNYKIDISSSS
SPIKE_CVHN2 VHVDSFSCNNLDKSKIFGSCFNSITVDKFAIPNRRRDDLQLGSSGFLQSSNYKIDISSSS
SPIKE_CVRSD VQAESLSCSNIDASKVYGMCFGSISIDKFAIPNSRRVDLQLGKSGLLQSFNYKIDTRATS
SPIKE_CVMA5 VQAESLFCNNIDASKVYGRCFGSISVDKFAVPRSRQVDLQLGNSGFLQTANYKIDTAATS
SPIKE_CVMJC VQAESLSCNNIDASKVYGMCFGSVSVDKFAIPRSRQIDLQIGNSGFLQTANYKIDTAATS
SPIKE_CVM4 VQAESLSCNNIDASKVYGMCFGSVSVDKFAIPRSRQIDLQIGNSGFLQTANYKIDTAATS
SPIKE_CVMJH VQAESLSCNNIDASKVYGMCFGSVSVDKFAIPRSRQIDLQIGNSGFLQTANYKIDTAATS
SPIKE_CVP67 IQADSFGCNNIDASRLYGMCFGSITIDKFAIPNSRKVDLQVGKSGYLQSFNYKIDTAVSS
SPIKE_CVPIA IQADSFGCNNIDASRLYGMCFGSITIDKFAIPNSRKVDLQVGKSGYLQSFNYKIDTAVSS
SPIKE_CVHOC IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBLS IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBOK IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBEN IQAYSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBLU IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBM IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBQ IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBL9 IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBV IQADSFTCNNIEAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTAAS
SPIKE_CVBF IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVBLY IQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATS
SPIKE_CVEMC FSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNPT
SPIKE_BCHK5 FQVSEFSCHQVSPSSLATGCYSSLTVDYFAYSTDMSSYLQPGSAGAIVQFNYKQDFSNPT
SPIKE_BC133 FAVDEFSCNGISPDAIARGCYSTLTVDYFAYPLSMKSYIRPGSAGNIPLYNYKQSFANPT
SPIKE_BCHK4 FAVDEFSCNGISPDSIARGCYSTLTVDYFAYPLSMKSYIRPGSAGNIPLYNYKQSFANPT
: * .. : *: .: * : : . : **
SPIKE_BCHK9 CLHAFYLN-----------------------------------------STAPYAVANRF
SPIKE_SARS CVLAWNTRNIDATSTG------NYNYKYRYLRH------GKLRPFERDISNVPFSPDGK-
SPIKE_BCHK3 CVIAWNTAKHD-----------TGNYYYRSHRK------TKLKPFERDLSS---------
SPIKE_BC279 CVIAWNTAQQD-----------QGQYYYRSYRK------EKLKPFERDLS----------
SPIKE_BCRP3 CVIAWNTAKQD-----------QGQYYYRSHRK------TKLKPFERDLS----------
SPIKE_CVHN1 CQLYYSLPAINVTINNYNPSSWNRRYGFNN---------FNLSSHSVVYSRYCFSVNNTF
SPIKE_CVHN5 CQLYYSLPLVNVTINNFNPSSWNRRYGFGS---------FNLSSYDVVYSDHCFSVNSDF
SPIKE_CVHN2 CQLYYSLPLVNVTINNFNPSSWNRRYGFGS---------FNVSSYDVVYSDHCFSVNSDF
SPIKE_CVRSD CQLYYSLAQDNVTVINHNPSSWNRRYGFNDVAT------FHSGEHDVAYAEACFTVGASY
SPIKE_CVMA5 CQLHYTLPKNNVTINNHNPSSWNRRYGFNDAGV------FGKNQHDVVYAQQCFTVRSSY
SPIKE_CVMJC CQLYYSLPKNNVTINNYNPSSWNRRYGFNDAGV------FGKSKHDVAYAQQCFIVRPSY
SPIKE_CVM4 CQLYYSLPKNNVTINNYNPSSWNRRYGFNDAGV------FGKSKHDVAYAQQCFTVRPSY
SPIKE_CVMJH CQLYYSLPKNNVTINNYNPSSWNRRYGFK-------------------------------
SPIKE_CVP67 CQLYYSLPAANVSVTHYNPSSWNRRYGFNNQSF------GSRGLHDAVYSQQCFNTPNTY
SPIKE_CVPIA CQLYYSLPAANVSVTHYNPSSWNRRYGFINQSF------GSRGLHDAVYSQQCFNTPNTY
SPIKE_CVHOC CQLYYNLPAANVSVSRFNPSTWNKRFGFIEDSVFKPRPAGVLTNHDVVYAQHCFKAPKNF
SPIKE_CVBLS CQLYYNLPAANVSVSRFNPSTWNRRFGFTEQSVFKPQPAGVFTDHDVVYAQHCFKAPTNF
SPIKE_CVBOK CQLYYNLPAANVSVSRFNPSIWNRRFGFTEQSVFKPQPAGVFTDHDVVYAQHCFKAPTNF
SPIKE_CVBEN CQLYYNLPAANVSVSRFNPSTWNRRFGFTEQSVFKPQPAGVFTDHDVVYAQHCFKASTNF
SPIKE_CVBLU CQLYYNLPAANVSVSRFNPSTWNRRFGFTEQSVFKPQPAGVFTDHDVVYAQHCFKAPTNF
SPIKE_CVBM CQLYYNLPAANVSVSRFNPSTWNRRFGFTEQFVFKPQPVGVFTHHDVVYAQHCFKAPSNF
SPIKE_CVBQ CQLYYNLPAANVSVSRFNPSTWNRRFGFTEQFVFKPQPVGVFTHHDVVYAQHCFKAPKNF
SPIKE_CVBL9 CQLYYNLPAANVSVSRFNPSTWNRRFGFTEQSVFKPQPVGVFTHHDVVYAQHCFKAPTNF
SPIKE_CVBV CQLYYNLPAANVSVSRFNPSTWNRRFGFTEQSVFKPQPVGVFTHHDVVYAQHCFKAPTNF
SPIKE_CVBF CQLYYNLPAANVSLSRFNPSIWNRRFGFTEQSVFKPQPVGVFTDHDVVYAQHCFKAPTNF
SPIKE_CVBLY CQLYYNLPAANVSVSRFNPSTWNRRFGFTEQSVFKPQPVGVFTDHDVVYAQHCFKAPTNF
SPIKE_CVEMC CLILATVPHNLTTITK------PLKYSYINKC-------SRFLSDDRT-EVPQLVNANQY
SPIKE_BCHK5 CRVLATVPQNLTTITK------PSNYAYLTEC-------YKTSAYGKNY---LYNAPGAY
SPIKE_BC133 CRVMASVP-DNVTITK------PGAYGYISKC-------SRLTGVNQDIETPLYINPGEY
SPIKE_BCHK4 CRVMASVL-ANVTITK------PHAYGYISKC-------SRLTGANQDVETPLYINPGEY
*
SPIKE_BCHK9 ----------------------PIKPGGRQSNSAFIDTV---------------------
SPIKE_SARS -PCTP-----------------PALNCYWPLNDYGFYTT---------------------
SPIKE_BCHK3 ----------------------DDGNGVYTLSTYDFNPN---------------------
SPIKE_BC279 ----------------------SDENGVYTLSTYDFYPS---------------------
SPIKE_BCRP3 ----------------------SDENGVRTLSTYDFYPS---------------------
SPIKE_CVHN1 CPCAKPSFASSCKSH-------KPPSASCPIGTNYRSCE--------STTVLDHTDWCRC
SPIKE_CVHN5 CPCADPSVVNSCAKS-------KPPSAICPAGTKYRHCD--------LDTTLYVKNWCRC
SPIKE_CVHN2 CPCADPSVVNSCVKS-------KPLSAICPAGTKYRHCD--------LDTTLYVNNWCRC
SPIKE_CVRSD CPCAKPSTVYSCVTG-------KPKSANCPTGTSNRECN---------VQASGFKSKCDC
SPIKE_CVMA5 CPCAQ-----------------PDIVSPCTTQTKPKSAF---------------------
SPIKE_CVMJC CPCAQPDIVSACTSQT------KPMSAYCPTGTIHRECSLWNGPHLRSARVGSGTYTCEC
SPIKE_CVM4 CPCAQPDIVSACTSQT------KPMSAYCPTGTIHRECSLWNGPHLRSARVGSGTYTCEC
SPIKE_CVMJH ------------------------------------------------------------
SPIKE_CVP67 CPCRT--SQCIGG----------AGTGTCPVGTTVRKCFA----------AVTKATKCTC
SPIKE_CVPIA CPCRT--SQCIGG----------AGTGTCPVGTTVRKCFA----------AVTNATKCTC
SPIKE_CVHOC CPCKLNGS-CVGSGPG-----KNNGIGTCPAGTNYLTCD--------------N------
SPIKE_CVBLS CPCKLDGSLCVGSGSGIDAGYKNTGIGTCPAGTNYLTCH--------------NAAQCGC
SPIKE_CVBOK CPCKLDGSLCVGSGSGIDAGYKNTGIGTCPAGTNYLTCH--------------NAAQCGC
SPIKE_CVBEN CPCKLDGSLCVGNGPGIDAGYKTSGIGTCPAGTNYLTCH--------------NAAQCDC
SPIKE_CVBLU CPCKLDGSLCVGNGPGIDAGYKTSGIGTCPAGTNYLTCH--------------NAAQCDC
SPIKE_CVBM CPCKLDGSLCVGNGPGIDAGYKNSGIGTCPAGTNYLTCH--------------NAAQCNC
SPIKE_CVBQ CPCKLDGSLCVGNGPGIDAGYKNSGIGTCPAGTNYLTCH--------------NAAQCDC
SPIKE_CVBL9 CPCKLDGSLCVGNGPGIDAGYKNSGIGTCPAGTNYLTCH--------------NAAQCDC
SPIKE_CVBV CPCKLDGSLCVGNGPGIDAGYKNSGIGTCPAGTNYLTCH--------------NAAQCDC
SPIKE_CVBF CPCKLDGSLCVGNGPGIDAGYKNSGIGTCPAGTNYLTCH--------------NAAQCNC
SPIKE_CVBLY CPCKLDGSLCVGSGSGIDAGYKNSGIGTCPAGTNYLTCH--------------NAAQCDC
SPIKE_CVEMC SPCVS-----------------IVPSTVWEDGDYYRKQL---------------------
SPIKE_BCHK5 TPCLS-----------------LASRGFSTKYQSHSDGE---------------------
SPIKE_BC133 SICRD-----------------FAPLGFSEDGQVFKRTL---------------------
SPIKE_BCHK4 SICRD-----------------FSPGGFSEDGQVFKRTL---------------------
SPIKE_BCHK9 -----------------------INAAHYSP-----------------------------
SPIKE_SARS -----------------------TGIGYQPY-----------------------------
SPIKE_BCHK3 -----------------------VPVAYQAT-----------------------------
SPIKE_BC279 -----------------------IPVEYQAT-----------------------------
SPIKE_BCRP3 -----------------------VPVAYQAT-----------------------------
SPIKE_CVHN1 SCLPDPITA--YDPRSCSQKKSLVGVGEHCAGFGVDEEKCGVLDGSYNVSCLCSTDAFLG
SPIKE_CVHN5 SCLPDPIST--YSPNTCPQKKVVVGIGEHCPGLGINEEKCG--TQLNHSSCFCSPDAFLG
SPIKE_CVHN2 SCLPDPIST--YSPNTCPQKKVVVGIGEHCPGLGINEEKCG--TQLNHSSCSCSPDAFLG
SPIKE_CVRSD TCNPSPLT---TYDPRCLQARSMLGVGDHCEGLGILEDKCG-----GSNICNCSADAFVG
SPIKE_CVMA5 -----------------------VNVGDHCEGLGVLEDNCG--NADPHKGCICANNSFIG
SPIKE_CVMJC TCKPNPFD---TYDLRCGQIKTIVNVGDHCEGLGVLEDKCG--NSDPHKGCSCAHDSFIG
SPIKE_CVM4 TCKPNPFD---TYDLRCGQIKTIVNVGDHCEGLGVLEDKCG--NSDPHKGCSCANDSFIG
SPIKE_CVMJH ------------------------------------------------------------
SPIKE_CVP67 WCQPDPSTYKGVNAWTCPQSKVSIQPGQHCPGLGLVEDDCS--GNP----CTCKPQAFIG
SPIKE_CVPIA WCQPDPSTYKGVNAWTCPQSKVSIQPGQHCPGLGLVEDDCS--GNP----CTCKPQAFIG
SPIKE_CVHOC LCTPDPITF--TGTYKCPQTKSLVGIGEHCSGLAVKSDYCG--GNS----CTCRPQAFLG
SPIKE_CVBLS LCTPDPITSKATGPYKCPQTKYLVGIGEHCSGLAIKSDYCG--GNP----CSCQPQAFLG
SPIKE_CVBOK LCTPDPITSKATGPYKCPQTKYLVGIGEHCSGLAIKSDYCG--GNP----CSCRPQAFLG
SPIKE_CVBEN LCTPDPITSKATGPYKCPQTKYLVGIGEHCSGLAIKSDHCG--GNP----CTCQPQAFLG
SPIKE_CVBLU LCTPDPITSKATGPYKCPQTKYLVGIGEHCSGLAIKSDHCG--GNP----CTCQPQAFLG
SPIKE_CVBM LCTPDPITSKSTGPYKCPQTKYLVGIGEHCSGLAIKSDYCG--GNP----CTCQPQAFLG
SPIKE_CVBQ LCTPDPITSKSTGPYKCPQTKYLVGIGEHCSGLAIKSDYCG--GNP----CTCQPQAFLG
SPIKE_CVBL9 LCTPDPITSKSTGPYKCPQTKYLVGIGEHCSGLAIKSDYCG--GNP----CTCQPQAFLG
SPIKE_CVBV LCTPDPITSKSTGPYKCPQTKYLVGIGEHCSGLAIKSDYCG--GNP----CTCQPQAFLG
SPIKE_CVBF LCTPDPITSKSTGPYKCPQTKYLVGIGEHCSGLAIKSDYCG--GNP----CTCQPQAFLG
SPIKE_CVBLY LCTPDPITSKSTGPYKCPQTKYLVGIGEHCSGLAIKSDYCG--GNP----CTCQPQAFLG
SPIKE_CVEMC --------------SPLEGGGWLVASGSTVA-----------------------------
SPIKE_BCHK5 ----------------------LTTTGYIYP-----------------------------
SPIKE_BC133 --------------TQFEGGGLLIGVGTRVP-----------------------------
SPIKE_BCHK4 --------------TQFEGGGLLIGVGTRVP-----------------------------
SPIKE_BCHK9 -------FSYVYGLAVITLKPAAGSKLVCP---VANDTVVITDR---CVQYNLYGYTGTG
SPIKE_SARS ----------RVVVLSFELLNA--PATVCGPKL---STDLIKNQ---CVNFNFNGLTGTG
SPIKE_BCHK3 ----------RVVVLSFELLNA--PATVCGPKL---STELVKNQ---CVNFNFNGLKGTG
SPIKE_BC279 ----------RVVVLSFELLNA--PATVCGPKL---STQLVKNQ---CVNFNFNGLRGTG
SPIKE_BCRP3 ----------RVVVLSFELLNA--PATVCGPKL---STQLVKNQ---CVNFNFNGLKGTG
SPIKE_CVHN1 WSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDV---CVDYDLYGITGQG
SPIKE_CVHN5 WSFDSCISNNRCNIFSNFIFNGINSGTTCSNDLLYSNTEISTGV---CVNYDLYGITGQG
SPIKE_CVHN2 WSFDSCISNNRCNIFSNFIFNGINSGTTCSNDLLYSNTEVSTGV---CVNYDLYGITGQG
SPIKE_CVRSD WAMDSCLSNARCHIFSNLMLNGINSGTTCSTDFQLPNTEVVTGV---CVKYDLYGSTGQG
SPIKE_CVMA5 WSHDTCLVNDRCQIFANILLNGINSGTTCSTDLQLPNTEVVTGI---CVKYDLYGITGQG
SPIKE_CVMJC WSHDTCLVNDHSQIFANILLNGINSGTTCSTDLQLPNTEVATGV---CVRYDLYGITGQG
SPIKE_CVM4 WSHDTCLVNDRCQIFANILLNGINSGTTCSTDLQLPNTEVATGV---CVRYDLYGITGQG
SPIKE_CVMJH -------VNDRCQIFANILLNGINSGTTCSTDLQLPNTEVATGV---CVRYDLYGITGQG
SPIKE_CVP67 WSSETCLQNGRCNIFANFILNDVNSGTTCSTDLQQGNTIITTDV---CVNYDLYGITGQG
SPIKE_CVPIA WSSETCLQNGRCNIFANFILNDVNSGTTCSTDLQQGNTNITTDV---CVNYDLYGITGQG
SPIKE_CVHOC WSADSCLQGDKCNIFANFILHDVNSGLTCSTDLQKANTDIILGV---CVNYDLYGILGQG
SPIKE_CVBLS WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBOK WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBEN WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBLU WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBM WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBQ WSVDSCLQGDRCNIFANFIFHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBL9 WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBV WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBF WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVBLY WSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV---CVNYDLYGITGQG
SPIKE_CVEMC ------MTEQLQMGFGITVQYGTDTNSVC-PKLEFANDTKIASQLGNCVEYSLYGVSGRG
SPIKE_BCHK5 ------VTGNLQMAFIISVQYGTDTNSVC-PMQALRNDTSIEDKLDVCVEYSLHGITGRG
SPIKE_BC133 ------MTANLEMGFVISVQYGTGTDSVC-PMLDLGDSLTITNRLGKCVDYSLYGVTGRG
SPIKE_BCHK4 ------MTDNLQMSFIISVQYGTGTDSVC-PMLDLGDSLTITNRLGKCVDYSLYGVTGRG
: . .* . . ** :.: * * *
SPIKE_BCHK9 VLSKNTSLVIPDGKVFTASSTGTIIGVS--INSTTYSIMPCVTVPVSVGY--HPNF-ERA
SPIKE_SARS VLTP-SSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVA
SPIKE_BCHK3 VLTS-SSKRFQSFQQFGRDTSDFTDSVRDPQTLEILDISPCSFGGVSVITPGTNASSEVA
SPIKE_BC279 VLTT-SSKRFQSFQQFGRDTSDFTDSVRDPQTLEILDISPCSFGGVSVITPGTNASSEVA
SPIKE_BCRP3 VLTE-SSKRFQSFQQFGRDTSDFTDSVRDPQTLEILDISPCSFGGVSVITPGTNASSEVA
SPIKE_CVHN1 IFKEVSAVYYNSWQNLLYDSNGNIIGFKDFVTNKTYNIFPCYAGRVSAAF--HQNASSLA
SPIKE_CVHN5 IFKEVSAAYYNNWQNLLYDSNGNIIGFKDFLTNKTYTILPCYSGRVSAAF--YQNSSSPA
SPIKE_CVHN2 IFKEVSAAYYNNWQNLLYDSNGNIIGFKDFLTNKTYTILPCYSGRVSAAF--YQNSSSPA
SPIKE_CVRSD VFKEVKADYYNSWQNLLYDVNGNLNGFRDIVTNKTYLLRSCYSGRVSAAY--HQDAPEPA
SPIKE_CVMA5 VFKEVKADYYNSWQTLLYDVNGNLNGFRDLTTNKTYTIRSCYSGRVSAAF--HKDAPEPA
SPIKE_CVMJC VFKEVKADYYNSWQALLYDVNGNLNGFRDLTTNKTYTIRSCYSGRVSAAY--HKEAPEPA
SPIKE_CVM4 VFKEVKADYYNSWQALLYDVNGNLNGFRDLTTNKTYTIRSCYSGRVSAAY--HKEAPEPA
SPIKE_CVMJH VFKEVKADYYNSWQALLYDVNGNLNGFRDLTTNKTYTIRSCYSGRVSAAY--HKEAPEPA
SPIKE_CVP67 ILIEVNATYYNSWQNLLYDSSGNLYGFRDYLSNRTFLIRSCYSGRVSAVF--HANSSEPA
SPIKE_CVPIA ILIEVNATYYNSWQNLLYDSSGNLYGFRDYLSNRTFLIRSCYSGRVSAVF--HANSSEPA
SPIKE_CVHOC IFVEVNATYYNSWQNLLYDSNGNLYGFRDYIINRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBLS IFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBOK IFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBEN IFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBLU IFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBM IFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBQ IFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBL9 IFVEVNAPYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBV IFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBF IFVEANATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVBLY IFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAF--HANSSEPA
SPIKE_CVEMC VFQNCTAVGVRQ-QRFVYDAYQNLVGYYS-DDGNYYCLRACVSVPVSVIY--DKETKTHA
SPIKE_BCHK5 VFHNCTSVGLRN-QRFVYDTFDNLVGYHS-DNGNYYCVRPCVSVPVSVIY--DKASNSHA
SPIKE_BC133 VFQNCTAVGVKQ-QRFVYDSFDNLVGYYS-DDGNYYCVRPCVSVPVSVIY--DKSTNLHA
SPIKE_BCHK4 VFQNCTAVGVKQ-QRFVYDSFDNLVGYYS-DDGNYYCVRPCVSVPVSVIY--DKSTNLHA
:: .: : : . . : .* **. *
SPIKE_BCHK9 LLFNGLSCSQRSRAV---TEPVSVLWSASATAQDAFDTPSGCVVNVELRNTTIVNTCAMP
SPIKE_SARS VLYQDVNCTDVSTAIH--ADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSY--ECDIP
SPIKE_BCHK3 VLYQDVNCTDVPTAIR--ADQLTPAWRVYSTGVNVFQTQAGCLIGAEHVNASY--ECDIP
SPIKE_BC279 VLYQDVNCTDVPTSIH--ADQLTPAWRVYSTGVNVFQTQAGCLIGAEHVNASY--ECDIP
SPIKE_BCRP3 VLYQDVNCTDVPAAIH--ADQLTPAWRVYSTGTNVFQTQAGCLIGAEHVNASY--ECDIP
SPIKE_CVHN1 LLYRNLKCSYV-----------LNNISLTTQP--YFDSYLGCVFNADNLTDYSVSSCALR
SPIKE_CVHN5 LLYRNLKCSYV-----------LNNISFISQPF-YFDSYLGCVLNAVNLTSYSVSSCDLR
SPIKE_CVHN2 LLYRNLKCSYV-----------LNNISFISQPF-YFDSYLGCVLNAVNLTSYSVSSCDLR
SPIKE_CVRSD LLYRNLKCDYV----------FNNNISREETPLNYFDSYLGCVINADNSTEQSVDACDLR
SPIKE_CVMA5 LLYRNINCSYV----------FSNNISREENPLNYFDSYLGCVVNADNRTDEALPNCDLR
SPIKE_CVMJC LLYRNINCSYV----------FTNNISREENPLNYFDSYLGCVVNADNRPDEALPNCDLR
SPIKE_CVM4 LLYRNINCSYV----------FTNNISREENPLNYFDSYLGCVVNADNRTDEALPNCDLR
SPIKE_CVMJH LLYRNINCSYV----------FTNNISREENPLNYFDSYLGCVVNADNRTDEALPNCNLR
SPIKE_CVP67 LMFRNLKCSHV----------FNNTILRQIQLVNYFDSYLGCVVNAYNNTASAVSTCDLT
SPIKE_CVPIA LMFRNLKCSHV----------FNYTILRQIQLVNYFDSYLGCVVNAYNNTASAVSTCDLT
SPIKE_CVHOC LLFRNIKCNYV----------FNNSLTRQLQPINYFDSYLGCVVNAYNSTAISVQTCDLT
SPIKE_CVBLS LLFRNFKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTCDLT
SPIKE_CVBOK LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTCDLT
SPIKE_CVBEN LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTCDLT
SPIKE_CVBLU LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTCDLT
SPIKE_CVBM LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTCDLT
SPIKE_CVBQ LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTCDLT
SPIKE_CVBL9 LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTCDLT
SPIKE_CVBV LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTCDLT
SPIKE_CVBF LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTASAVQTCDLT
SPIKE_CVBLY LLFRNIKCNYV----------FNNTLSRQLQPINYFDSYLGCVVNADNSTSSAVQTCDLT
SPIKE_CVEMC TLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGPLQTPVGCVLGLVN-SSLFVEDCKLP
SPIKE_BCHK5 TLFGSVACSHVTTMMSQFSRMTKTNLLARTTP-GPLQTTVGCAMGFIN-SSMVVDECQLP
SPIKE_BC133 TLFGSVACEHVTTMMSQFSRLTQSNLRRRDSNT-PLQTAVGCVIGLSN-NSLVVSDCKLP
SPIKE_BCHK4 TLFGSVACEHVTTMMSQFSRLTQSNLRRRDSNI-PLQTAVGCVIGLSN-NSLVVSDCKLP
:: .. * ::: ** .. * :
SPIKE_BCHK9 IGNSLCFING-----SIATANADSLPRLQLVNYDPLYDNSTATPMTPV---YWVKVPTNF
SPIKE_SARS IGAGICASYHTVS--LLRSTSQKSIVAYTMSLGADSSIAYSNNTI---------AIPTNF
SPIKE_BCHK3 IGAGICASYHTAS--VLRSTGQKSIVAYTMSLGAENSIAYANNSI---------AIPTNF
SPIKE_BC279 IGAGICASYHTAS--VLRSTGQKSIVAYTMSLGAENSIAYANNSI---------AIPTNF
SPIKE_BCRP3 IGAGICASYHTAS--TLRSVGQKSIVAYTMSLGAENSIAYANNSI---------AIPTNF
SPIKE_CVHN1 MGSGFCVDYNSPSSSSSRRKRRSISASYRFVTFEPFNVSFVNDSIESVGGLYEIKIPTNF
SPIKE_CVHN5 MGSGFCIDYALP---SSRRKRRGISSPYRFVTFEPFNVSFVNDSVETVGGLFEIQIPTNF
SPIKE_CVHN2 MGSGFCIDYALP---SSRRKRRGISSPYRFVTFEPFNVSFVNDSVETVGGLFEIQIPTNF
SPIKE_CVRSD MGSGLCVNYS-----IAHRARRSVSTGYKLTTFEPFTVSIVNDSVESVGGLYEMQIPTNF
SPIKE_CVMA5 MGAGLCVDYS-----KSRRAHRSVSTGYRLTTFEPYTPMLVNDSVQSVDGLYEMQIPTNF
SPIKE_CVMJC MGAGLCVDYS-----KSRRARRSVSTGYRLTTFEPYMPMLVNDSVQSVGGLYEMQIPTNF
SPIKE_CVM4 MGAGLCVDYS-----KSRRARRSVSTGYRLTTFEPYMPMLVNDSVQSVGGLYEMQIPTNF
SPIKE_CVMJH MGAGLCVDYS-----KSRRARRSVSTGYRLTTFEPYMPMLVNDSVQSVGGLYEMQIPTNF
SPIKE_CVP67 VGSGYCVDYV-----TALRSRRSFTTGYRFTNFEPFAANLVNDSIEPVGGLYEIQIPSEF
SPIKE_CVPIA VGSGYCVDYV-----TALRSRRSFTTGYRFTNFEPFAANLVNDSIEPVGGLYEIQIPSEF
SPIKE_CVHOC VGSGYCVDYS-----KNRRSRGAITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBLS VGSGYCVDYS-----TKRRSRRSITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBOK VGSGYCVDYS-----TKRRSRRSITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBEN VGSGYCVDYS-----TKRRSRRSITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBLU VGSGYCVDYS-----TKRRSRRSITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBM VGSGYCVDYS-----TKRRSRRAITTGYRFTTFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBQ VGSGYCVDYS-----TKRRSRRAITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBL9 VGSGYCVDYS-----TKRRSRRAITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBV VGSGYCVDYS-----TKRRSRRAITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBF VGSGYCVDYS-----TKRRSVRAITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVBLY VGSGYCVDYS-----TKRRSRRAITTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEF
SPIKE_CVEMC LGQSLCALPDTPST-LTPRSVRSVPGEMRLASIA-FNHPIQVDQLNSSY--FKLSIPTNF
SPIKE_BCHK5 LGQSLCAIPPTTSS-RVRRATSGASDVFQIATLN-FTSPLTLAPINSTG--FVVAVPTNF
SPIKE_BC133 LGQSLCAVP------PVSMFRSYSASQFQLAVLN-YTSPIVVTPINSSG--FTAAIPTNF
SPIKE_BCHK4 LGQSLCAVP------PVSTFRSYSASQFQLAVLN-YTSPIVVTPINSSG--FTAAIPTNF
:* . * : : :*::*
SPIKE_BCHK9 TLSATEEYIQTTAPKITIDCARYLCGDSSRCLNVLLHYGTFCNDINKALSRVSTILDSAL
SPIKE_SARS SISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNT
SPIKE_BCHK3 SISVTTEVMPVSMAKTAVDCTMYICGDSLECSNLLLQYGSFCTQLNRALTGIAIEQDKNT
SPIKE_BC279 SISVTTEVMPVSIAKTSVDCTMYICGDSLECSNLLLQYGSFCTQLNRALTGIAIEQDKNT
SPIKE_BCRP3 SISVTTEVMPVSMAKTSVDCTMYICGDSLECSNLLLQYGSFCTQLNRALSGIAIEQDKNT
SPIKE_CVHN1 TIVGQEEFIQTNSPKVTIDCSLFVCSNYAACHDLLSEYGTFCDNINSILDEVNGLLDTTQ
SPIKE_CVHN5 TIAGHEEFIQTSSPKVTIDCSAFVCSNYAACHDLLSEYGTFCDNINSILNEVNDLLDITQ
SPIKE_CVHN2 TIAGHEEFIQTSSPKVTIDCSAFVCSNYAACHDLLSEYGTFCDNINSILNEVNDLLDITQ
SPIKE_CVRSD TIASHQEFIQTRSPKVTIDCAAFVCGDYTACRQQLVDYGSFCDNINAILGEVNNLIDTMQ
SPIKE_CVMA5 TIGHHEEFIQTRSPKVTIDCAAFVCGDNTACRQQLVEYGSFCVNVNAILNEVNNLLDNMQ
SPIKE_CVMJC TIGHHEEFIQIRAPKVTIDCAAFVCGDNAACRQQLVEYGSFCDNVNAILNEVNNLLDNMQ
SPIKE_CVM4 TIGHHEEFIQIRAPKVTIDCAAFVCGDNAACRQQLVEYGSFCDNVNAILNEVNNLLDNMQ
SPIKE_CVMJH TIGHHEEFIQIRAPKVTIDCAAFVCGDNAACRQQLVEYGSFCDNVNAILNEVNNLLDNMQ
SPIKE_CVP67 TIGNLEEFIQTRSPKVTIDCATFVCGDYAACRQQLAEYGSFCENINAILTEVNELLDTTQ
SPIKE_CVPIA TIGNLEEFIQTSSPKVTIDCATFVCGDYAACRQQLAEYGSFCENINAILIEVNELLDTTQ
SPIKE_CVHOC TIGNMVEFIQTSSPKVTIDCAAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBLS TIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBOK TIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBEN TIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBLU TIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBM TIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBQ TIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBL9 TIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBV TIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBF TIGNMEEFIQTSSPKVTIDCSAFVCGDCAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVBLY TIGNMEEFIQISSPKVTIDCSAFVCGDYAACKSQLVEYGSFCDNINAILTEVNELLDTTQ
SPIKE_CVEMC SFGVTQEYIQTTIQKVTVDCKQYVCNGFQKCEQLLREYGQFCSKINQALHGANLRQDDSV
SPIKE_BCHK5 TFGVTQEFIETTIQKITVDCKQYVCNGFKKCEDLLKEYGQFCSKINQALHGANLRQDESI
SPIKE_BC133 SFSLTQEYIETSIQKVTVDCKQYVCNGFTRCEKLLVEYGQFCSKINQALHGANLRQDESV
SPIKE_BCHK4 SFSVTQEYIETSIQKVTVDCKQYVCNGFTRCEKLLVEYGQFCSKINQALHGANLRQDESV
:: * : * ::** ::*.. * . * ** ** .:* * *
SPIKE_BCHK9 LSLVKELSIN-TRDEVTTFSFDGD---YNFTGL-MGCLGPNCGA----TTY---RSAFSD
SPIKE_SARS REVFAQVKQ--MYKTPTLKYFGG----FNFSQI-LPDPLK--------PTK---RSFIED
SPIKE_BCHK3 QEVFAQVKQ--MYKTPAIKDFGG----FNFSQI-LPDPSK--------PTK---RSFIED
SPIKE_BC279 QEVFAQVKQ--MYKTPAIKDFGG----FNFSQI-LPDPSK--------PTK---RSFIED
SPIKE_BCRP3 QEVFAQVKQ--MYKTPAIKDFGG----FNFSQI-LPDPSK--------PTK---RSFIED
SPIKE_CVHN1 LHVADTLMQGVTLSSNLNTNLHFDVDNINFKSL-VGCLGPHCG-----SSS---RSFFED
SPIKE_CVHN5 LQVANALMQGVTLSSNLNTNLHSDVDNIDFKSL-LGCLGSQCG-----SSS---RSLLED
SPIKE_CVHN2 LQVANALMQGVTLSSNLNTNLHSDVDNIDFKSL-LGCLGSQCG-----SSS---RSLLED
SPIKE_CVRSD LQVASALIQGVTLSSRLADGISGQIDDINFSPL-LGCLGSDCSEGTKAAQG---RSAIED
SPIKE_CVMA5 LQVASALMQGVTISSRLPDGISGPIDDINFSPL-LGCIGSTCAEDGNGPSAIRGRSAIED
SPIKE_CVMJC LQVASALMQGVTISSRLPDGISGPIDDINFSPL-LGCIGSTCAEDGNGPSAMRGRSAIED
SPIKE_CVM4 LQVASALMQGVTISSRLPDGISGPIDDINFSPL-LGCIGSTCAEDGNGPSAIRGRSAIED
SPIKE_CVMJH LQVASALMQGVTISSRLPDGISGPIDDINFSPL-LGCIGSTCAEDGNGPSAIRGRSAIED
SPIKE_CVP67 LQVANSLMNGVTLSTKIKDGINFNVDDINFSPV-LGCLGSECNR----AST---RSAIED
SPIKE_CVPIA LQVANSLMNGVTLSTKIKDGINFNVDDINFSSV-LGCLGSECNR----AST---RSAIED
SPIKE_CVHOC LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSECSK----ASS---RSAIED
SPIKE_CVBLS LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSDCNK----VSS---RSAIED
SPIKE_CVBOK LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSDCNK----VSS---RSAIED
SPIKE_CVBEN LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSDCNK----VSS---RSAIED
SPIKE_CVBLU LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSDCNK----VSS---RSAIED
SPIKE_CVBM LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSDCNK----VSS---RSAIED
SPIKE_CVBQ LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSACNK----VSS---RSAIED
SPIKE_CVBL9 LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSDCNK----VSS---RSAIED
SPIKE_CVBV LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSDCNK----VSS---RSAIED
SPIKE_CVBF LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSECNK----VSS---RSAIED
SPIKE_CVBLY LQVANSLMNGVTLSTKLKDGVNFNVDDINFSPV-LGCLGSDCNK----VSS---RSAIED
SPIKE_CVEMC RNLFASVKS--SQSSPIIPGFGG---DFNLTLLEPVSISTGS------RSA---RSAIED
SPIKE_BCHK5 ANLFSSIKT--QNTQPLQAGLNG---DFNLTMLQIPQVTTGE------RKY---RSTIED
SPIKE_BC133 YSLYSNIKT--TSTQTLEYGLNG---DFNLTLLQVPQIGG--------SSY---RSAIED
SPIKE_BCHK4 YSLYSNIKT--TSTQTLEYGLNG---DFNLTLLQVPQIGGSS------SSY---RSAIED
: : . ::. : ** :.*
SPIKE_BCHK9 LLYDKVRITDPGFMQSYQKCIDSQWGGSIRDLLCTQTYNGIAVLPPIVSPAMQALYTSLL
SPIKE_SARS LLFNKVTLADAGFMKQYGEC--LG-DINARDLICAQKFNGLTVLPPLLTDDMIAAYTAAL
SPIKE_BCHK3 LLFNKVTLADAGFMKQYGDC--LG-DVSARDLICAQKFNGLTVLPPLLTDEMVAAYTAAL
SPIKE_BC279 LLFNKVTLADAGFMKQYGEC--LG-DISARDLICAQKFNGLTVLPPLLTDEMIAAYTAAL
SPIKE_BCRP3 LLFNKVTLADAGFMKQYGEC--LG-DISARDLICAQKFNGLTVLPPLLTDEMIAAYTAAL
SPIKE_CVHN1 LLFDKVKLSDVGFVEAYNNC--TG-GSEIRDLLCVQSFNGIKVLPPILSESQISGYTTAA
SPIKE_CVHN5 LLFNKVKLSDVGFVEAYNNC--TG-GSEIRDLLCVQSFNGIKVLPPILSETQISGYTTAA
SPIKE_CVHN2 LLFNKVKLSDVGFVEAYNNC--TG-GSEIRDLLCVQSFNGIKVLPPILSETQISGYTTAA
SPIKE_CVRSD VLFDKVKLSDVGFVESYNNC--TG-GQEVRDLLCVQSFNGIKVLPPVLSESQISGYTAGA
SPIKE_CVMA5 LLFDKVKLSDVGFVEAYNNC--TG-GQEVRDLLCVQSFNGIKVLPPVLSESQISGYTTGA
SPIKE_CVMJC LLFDKVKLSDVGFVEAYNNC--TG-GQEVRDLLCVQSFNGIKVLPPVLSESQISGYTAGA
SPIKE_CVM4 LLFDKVKLSDVGFVEAYNNC--TG-GQEVRDLLCVQSFNGIKVLPPVLSESQISGYTAGA
SPIKE_CVMJH LLFDKVKLSDVGFVEAYNNC--TG-GQEVRDLLCVQSFNGIKVLPPVLSESQISGYTAGA
SPIKE_CVP67 LLFDKVKLSDVGFVQAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAA
SPIKE_CVPIA LLFDKVKLSDVGFVQAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSENQISGYTSAA
SPIKE_CVHOC LLFDKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYKGIKVLPPLLSENQISGYTLAA
SPIKE_CVBLS LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAA
SPIKE_CVBOK LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAA
SPIKE_CVBEN LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAA
SPIKE_CVBLU LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAA
SPIKE_CVBM LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSVNQISGYTLAA
SPIKE_CVBQ LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSVNQISGYTLAA
SPIKE_CVBL9 LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSVNQISGYTLAA
SPIKE_CVBV LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSVNQISGYTLAA
SPIKE_CVBF LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAA
SPIKE_CVBLY LLFSKVKLSDVGFVEAYNNC--TG-GAEIRDLICVQSYNGIKVLPPLLSENQISGYTLAA
SPIKE_CVEMC LLFDKVTIADPGYMQGYDDCMQQG-PASARDLICAQYVAGYKVLPPLMDVNMEAAYTSSL
SPIKE_BCHK5 LLFNKVTIADPGYMQGYDECMQQG-PQSARDLICAQYVAGYKVLPPLYDPYMEAAYTSSL
SPIKE_BC133 LLFDKVTIADPGYMQGYDDCMKQG-PQSARDLICAQYVSGYKVLPPLYDPNMEAAYTSSL
SPIKE_BCHK4 LLFDKVTIADPGYMQGYDDCMKQG-PQSARDLICAQYVSGYKVLPPLYDPNMEAAYTSSL
:*:.** ::* *::: * .* . ***:*.* * ****: : **
SPIKE_BCHK9 VGAVASSGYTFGITSAGVIPFATQLQFRLNGIGVTTQVLVENQKLIASSFNNALVNIQKG
SPIKE_SARS VSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQES
SPIKE_BCHK3 VSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQES
SPIKE_BC279 VSGTATAGWTFGAGSALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQES
SPIKE_BCRP3 VSGTATAGWTFGAGSALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQES
SPIKE_CVHN1 TVAAMFPPWSAAAG----IPFSLNVQYRINGLGVTMDVLNKNQKLIATAFNNALLSIQNG
SPIKE_CVHN5 TVAAMFPPWSAAAG----VPFSLNVQYRINGLGVTMDVLNKNQKLIANAFNKALLSIQNG
SPIKE_CVHN2 TVAAMFPPWSAAAG----VPFSLNVQYRINGLGVTMDVLNKNQKLIANAFNKALLSIQNG
SPIKE_CVRSD TASAMFPPWSAAAG----VPFALSVQYRINGLGVTMNVLSENQKMIASSFNNAIGAIQEG
SPIKE_CVMA5 TAAAMFPPWSAAAG----VPFSLSVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQDG
SPIKE_CVMJC TAAAMFPPWTAAAG----VPFSLNVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQEG
SPIKE_CVM4 TAAAMFPPWTAAAG----VPFSLNVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQEG
SPIKE_CVMJH TAAAMFPPWTAAAG----VPFSLNVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQEG
SPIKE_CVP67 TAASLFPPWTAAAG----VPFYLNVQYRINGLGVTMDVLSQNQKLIASAFNNALDAIQEG
SPIKE_CVPIA TAASLFPPWTAAAG----VPFYLNVQYRINGLGVTMDVLSQNQKLIASAFNNALDSIQEG
SPIKE_CVHOC TSASLFPPWTAAAG----VPFYLNVQYRINGLGVTMDVLSQNQKLIANAFNNALYAIQEG
SPIKE_CVBLS TSASLFPPWSAAAG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALGAIQEG
SPIKE_CVBOK TSASLFPPWSAAAG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALGAIQEG
SPIKE_CVBEN TSASLFPPWSAAAG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALGAIQEG
SPIKE_CVBLU TSASLFPPWSAAAG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALGAIQEG
SPIKE_CVBM TSASLFPPLSAAVG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALDAIQEG
SPIKE_CVBQ TSASLFPPLSAAVG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALDAIQEG
SPIKE_CVBL9 TSASLFPPWSAAAG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALDAIQEG
SPIKE_CVBV TSASLFPPWSAAAG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALDAIQEG
SPIKE_CVBF TSASLFPPWSAAAG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALDAIQEG
SPIKE_CVBLY TSASLFPPWSAAAG----VPFYLNVQYRINGIGVTMDVLSQNQKLIANAFNNALDAIQEG
SPIKE_CVEMC LGSIAGVGWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTG
SPIKE_BCHK5 LGSIAGASWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKIIANKFNQALGAMQTG
SPIKE_BC133 LGSIAGAGWTAGLSSFAAIPFAQSMFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTG
SPIKE_BCHK4 LGSIAGAGWTAGLSSFAAIPFAQSMFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTG
. : . :** .: :*:**:*:* :** :*** **. **.*: :* .
SPIKE_BCHK9 FTETSIALSKMQDVINQHAAQLHTLVVQLGNSFGAISSSINEIFSRLEGLAANAEVDRLI
SPIKE_SARS LTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLI
SPIKE_BCHK3 LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLI
SPIKE_BC279 LTTTSTALGKLQDVVNDNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLI
SPIKE_BCRP3 LTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLI
SPIKE_CVHN1 FSATNSALAKIQSVVNSNAQALNSLLQQLFNKFGAISSSLQEILSRLDALEAQVQIDRLI
SPIKE_CVHN5 FTATNSALAKIQSVVNANAQALNSLLQQLFNKFGAISSSLQEILSRLDNLEAQVQIDRLI
SPIKE_CVHN2 FTATNSALAKIQSVVNANAQALNSLLQQLFNKFGAISSSLQEILSRLDNLEAQVQIDRLI
SPIKE_CVRSD FDATNSALAKIQSVVNANAEALNNLLNQLSNRFGAISASLQEILSRLDALEAQAQIDRLI
SPIKE_CVMA5 FDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISASLQEILTRLEAVEAKAQIDRLI
SPIKE_CVMJC FDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISASLQEILTRLDRVEAKAQIDRLI
SPIKE_CVM4 FDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISASLQEILTRLDAVEAKAQIDRLI
SPIKE_CVMJH FDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISASLQEILTRLDAVEAKAQIDRLI
SPIKE_CVP67 FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEILSRLDALEAKAQIDRLI
SPIKE_CVPIA FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEILSRLDALEAKAQIDRLI
SPIKE_CVHOC FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEILSRLDALEAEAQIDRLI
SPIKE_CVBLS FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVBOK FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVBEN FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVBLU FDATNSALVKIQAVVNANAETLNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVBM FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVBQ FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVBL9 FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVBV FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVBF FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQRQIDRLI
SPIKE_CVBLY FDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLI
SPIKE_CVEMC FTTTNEAFHKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQDAQIDRLI
SPIKE_BCHK5 FTTTNLAFNKVQDAVNANAMALSKLAAELSNTFGAISSSISDILARLDTVEQEAQIDRLI
SPIKE_BC133 FTTSNLAFSKVQDAVNANAQALSKLASELSNTFGAISSSISDILARLDTVEQDAQIDRLI
SPIKE_BCHK4 FTTSNLAFSKVQDAVNANAQALSKLASELSNTFGAISSSISDILARLDTVEQDAQIDRLI
: : *: *:* .:* :* * .* :* . *****: : :*: **: : . ::****
SPIKE_BCHK9 NGRMMVLNTYVTQLLIQASEAKAQNALAAQKISECVKAQSLRNDFCGNGTHVLSIPQLAP
SPIKE_SARS TGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAP
SPIKE_BCHK3 TGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAP
SPIKE_BC279 TGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAP
SPIKE_BCRP3 TGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAP
SPIKE_CVHN1 NGRLTALNAYVSQQLSDISLVKFGAALAMEKVNECVKSQSPRINFCGNGNHILSLVQNAP
SPIKE_CVHN5 NGRLTALNAYVSQQLSDITLIKAGASRAIEKVNECVKSQSPRINFCGNGNHILSLVQNAP
SPIKE_CVHN2 NGRLTALNAYVSQQLSDITLIKAGASRAIEKVNECVKSQSPRINFCGNGNHILSLVQNAP
SPIKE_CVRSD NGRLTALNAYVSKQLSDMTLIKVSAAQAIEKVNECVKSQSPRINFCGNGNHILSLVQNAP
SPIKE_CVMA5 NGRLTALNAYISKQLSDSTLIKVSAAQAIEKVNECVKSQTTRINFCGNGNHILSLVQNAP
SPIKE_CVMJC NGRLTALNAYISKQLSDSTLIKFSAAQAIEKVNECVKSQTTRINFCGNGNHILSLVQNAP
SPIKE_CVM4 NGRLTALNAYISKQLSDSTLIKFSAAQAIEKVNECVKSQTTRINFCGNGNHILSLVQNAP
SPIKE_CVMJH NGRLTALNAYISKQLSDSTLIKFSAAQAIEKVNECVKSQTTRINFCGNGNHILSLVQNAP
SPIKE_CVP67 NGRLTALNAYVSQQLSDSTLVKFSAAQAIEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVPIA NGRLTALNAYVSQQLSDSTLVKFSAAQAIEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVHOC NGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBLS NGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBOK NGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBEN NGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBLU NGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBM NGRLTALNVYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBQ NGRLTALNVYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBL9 NGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBV NGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBF NGRFTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVBLY NGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAP
SPIKE_CVEMC NGRLTTLNAFVAQQLVRSESAALSAQLAKDKVNECVKAQSKRSGFCGQGTHIVSFVVNAP
SPIKE_BCHK5 NGRLTSLNAFVAQQLVRTEAAARSAQLAQDKVNECVKSQSKRNGFCGTGTHIVSFAINAP
SPIKE_BC133 NGRLTSLNAFVSQQLVRSETAARSAQLASDKVNECVKSQSKRNGFCGSGTHIVSFVVNAP
SPIKE_BCHK4 NGRLISLNAFVSQQLVRSETAARSAQLASDKVNECVKSQSKRNGFCGSGTHIVSFVVNAP
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SPIKE_BCHK9 NGVLFIHYAYTPTEYAFVQTSAGLCHNG---TGYAPRQGMFVLPNNTNM-------WHFT
SPIKE_SARS HGVVFLHVTYVPSQERNFTTAPAICHEG---KAYFPREGVFVFNGTS---------WFIT
SPIKE_BCHK3 HGVVFLHVTYVPSQEKNFTTAPAICHEG---KAYFPREGVFVSNGTS---------WFIT
SPIKE_BC279 HGVVFLHVTYVPSQERNFTTAPAICHEG---KAYFPREGVFVSNGTS---------WFIT
SPIKE_BCRP3 HGVVFLHVTYVPSQERNFTTAPAICHEG---KAYFPREGVFVSNGTS---------WFIT
SPIKE_CVHN1 YGLLFMHFSYKPISFKTVLVSPGLCISGD--VGIAPKQGYFIKHNDH---------WMFT
SPIKE_CVHN5 YGLLFIHFSYKPTSFKTVLVSPGLCLSGD--RGIAPKQGYFIKQNDS---------WMFT
SPIKE_CVHN2 YGLLFIHFSYKPTSFKTVLVSPGLCLSGD--RGIAPKQGYFIKQNDS---------WMFT
SPIKE_CVRSD YGLYFIHFSYVPTSFTTVNVSPGLCISGD--RGLAPKAGYFVQDHGE---------WKFT
SPIKE_CVMA5 YGLYFIHFSYVPISFTTANVSPGLCISGD--RGLAPKAGYFVQDDGE---------WKFT
SPIKE_CVMJC YGLCFIHFSYVPTSFKTANVSPGLCISGD--RGLAPKAGYFVQDNGE---------WKFT
SPIKE_CVM4 YGLCFIHFSYVPTSFKTANVSPGLCISGD--RGLAPKAGYFVQDNGE---------WKFT
SPIKE_CVMJH YGLCFIHFSYVPTSFKTANVSPGLCISGD--RGLAPKAGYFVQDNGE---------WKFT
SPIKE_CVP67 YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--IGISPKSGYFINVNNS---------WMFT
SPIKE_CVPIA YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--IGISPKSGYFINVNNS---------WMFT
SPIKE_CVHOC YGLYFIHFSYVPTKYVTARVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMYT
SPIKE_CVBLS YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBOK YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBEN YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBLU YGLYFIHFSYVPTKYVTAKVSPGLCIAGG--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBM YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBQ YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBL9 YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBV YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBF YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVBLY YGLYFIHFSYVPTKYVTAKVSPGLCIAGD--RGIAPKSGYFVNVNNT---------WMFT
SPIKE_CVEMC NGLYFMHVGYYPSNHIEVVSAYGLCDAANPTNCIAPVNGYFIKTNNTRIVDE----WSYT
SPIKE_BCHK5 NGLYFFHVGYQPTSHVNATAAYGLCNTENPQKCIAPIDGYFVLNQTTSTVADSDQQWYYT
SPIKE_BC133 NGFYFFHVGYVPTNYTNVTAAYGLCNHNNPPLCIAPIDGYFITNQTTTYSVDTE--WYYT
SPIKE_BCHK4 NGFYFFHVGYVPTNYTNVTAAYGLCNNNNPPLCIAPIDGYFITNQTTTYSVDTE--WYYT
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SPIKE_BCHK9 TMQFYNPVNISASNTQVLTSCSVNYTSVNYTVLEPSVPGDY--DFQKEFDKFYKNLSTIF
SPIKE_SARS QRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELD--SFKEELDKYFKNHTSPD
SPIKE_BCHK3 QRNFYSPQLITTDNTFVSGNCDVVIGIINNTVYDPLQPELD--SFKEELDKYFKNHTSPD
SPIKE_BC279 QRNFYSPQIITTDNTFVAGNCDVVIGIINNTVYDPLQPELD--SFKEELDKYFKNHTSPD
SPIKE_BCRP3 QRNFYSPQIITTDNTFVAGSCDVVIGIINNTVYDPLQPELD--SFKEELDKYFKNHTSPD
SPIKE_CVHN1 GSSYYYPEPISDKNVVFMNTCSVNFTKAPLVYLNHSVPKLS--DFESELSHWFKNQTSIA
SPIKE_CVHN5 GSSYYYPEPISDKNVVFMNSCSVNFTKAPFIYLNNSIPNLS--DFEAELSLWFKNHTSIA
SPIKE_CVHN2 GSSYYYPEPISDKNVVFMNSCSVNFTKAPFIYLNNSIPNLS--DFEAEFSLWFKNHTSIA
SPIKE_CVRSD GSNYYYPESITDKNSVVMSSCAVNYTKAPEVFLNTSITNLP--DFKEELDKWFKNQTSIV
SPIKE_CVMA5 GSSYYYPEPITDKNSVIMSSCAVNYTKAPEVFLNTSIPNPP--DFKEELDKWFKNQTSIA
SPIKE_CVMJC GSNYYYPEPITDKNSVVMISCAVNYTKAPEVFLNNSIPNLP--DFKEELDKWFKNQTSIA
SPIKE_CVM4 GSNYYYPEPITDKNSVVMISCAVNYTKAPEVFLNNSIPNLP--DFKEELDKWFKNQTSIA
SPIKE_CVMJH GSNYYYPEPITDKNSVAMISCAVNYTKAPEVFLNNSIPNLP--DFKEELDKWFKNQTSIA
SPIKE_CVP67 GSSYYYPEPITQNNVVVMSTCAVNYTKAPDLMLNTSTPNLP--DFKEELYQWFKNQSSVA
SPIKE_CVPIA GSGYYYPEPITQNNVVVMSTCAVNYTKAPDLMLNTSTPNLP--DFKEELYQWFKNQSSLA
SPIKE_CVHOC GSGYYYPEPITENNVVVMSTCAVNYTKAPYVMLNTSIPNLP--DFKEELDQWFKNQTSVA
SPIKE_CVBLS GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLP--DFKEELDQWFKNQTSVA
SPIKE_CVBOK GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLP--DFKEELDQWFKNQTSVA
SPIKE_CVBEN GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLP--YFKEELDQWFKNQTSVA
SPIKE_CVBLU GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLP--DFKEELDQWFKNQTSVA
SPIKE_CVBM GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLH--DFKEELDQWFKNQTSVA
SPIKE_CVBQ GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLH--DFKEELDQWFKNQTSVA
SPIKE_CVBL9 GSGYYYPEPITGNNVVVMSTCAANYTKAPDVMLNISTPNLH--DFKEELDQWFKNQTSVA
SPIKE_CVBV GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLH--DFKEELDQWFKNQTSVA
SPIKE_CVBF GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLP--DFKEELDQWFKNQTSVA
SPIKE_CVBLY GSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLP--DFKEELDQWFKNQTSVA
SPIKE_CVEMC GSSFYAPEPITSLNTKYVAP-QVTYQNISTNLPPPLLGNSTGIDFQDELDEFFKNVSTSI
SPIKE_BCHK5 GSSFFHPEPITEANSKYVSM-DVKFENLTNRLPPPLLSNSTDLDFKEELEEFFKNVSSQG
SPIKE_BC133 GSSFFKPEPITQANSRYVSS-DVKFEKLENNLPPPLLENSTDVDFKDELEEFFKNVTSHG
SPIKE_BCHK4 GSSFYKPEPITQANSRYVSS-DVKFDKLENNLPPPLLENSTDVDFKDELEEFFKNVTSHG
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SPIKE_BCHK9 NNTF-NPNDFNFSTVDVTAQIKSLHDVVNQLNQSFIDLKKLNVYEKTIKWPWYVWLAMIA
SPIKE_SARS VDLG-DISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIA
SPIKE_BCHK3 VDLG-DISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIA
SPIKE_BC279 VDLG-DISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIA
SPIKE_BCRP3 VDLG-DISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIA
SPIKE_CVHN1 PNLTLNLHTINATFLDLYYEMNLIQESIKSLNNSYINLKDIGTYEMYVKWPWYVWLLISF
SPIKE_CVHN5 PNLTFNSH-INATFLDLYYEMNVIQESIKSLNSSFINLKEIGTYEMYVKWPWYIWLLIVI
SPIKE_CVHN2 PNLTFNSH-INATFLDLYYEMNVIQESIKSLNSSFINLKEIGTYEMYVKWPWYIWLLIVI
SPIKE_CVRSD PDLSFDIGKLNVTFLDLSYEMNRIQDAIKNLNESYINLKEIGTYEMYVKWPWYVWLLIGL
SPIKE_CVMA5 PDLSLDFEKLNVTLLDLTYEMNRIQDAIKKLNESYINLKEVGTYEMYVKWPWYVWLLIGL
SPIKE_CVMJC PDLSLDFEKLNVTFLDLTYEMNRIQDAIKKLNESYINLKEVGTYEMYVKWPWYVWLLIGL
SPIKE_CVM4 PDLSLDFEKLNVTFLDLTYEMNRIQDAIKKLNESYINLKEVGTYEMYVKWPWYVWLLIGL
SPIKE_CVMJH PDLSLDFEKLNVTFLDLTYEMNRIQDAIKKLNESYINLKEVGTYEMYVKWPWYVWLLIGL
SPIKE_CVP67 PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGL
SPIKE_CVPIA PDLSFDY--INVTFLDLQDEMNRLQEAIKVLNHSYINLKDIGTYEYYVKWPWYVWLLICL
SPIKE_CVHOC PDLSLDY--INVTFLDLQVEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLICL
SPIKE_CVBLS PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBOK PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBEN PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBLU PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBM PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBQ PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBL9 PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBV PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBF PDLSLDY--INVTFLDLQDEMNRLQEAIKLLNQSYINLKDIGTYEYYVKWPWYVWLLIGF
SPIKE_CVBLY PDLSLDY--INVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGL
SPIKE_CVEMC PNFG-SLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKELGNYTYYNKWPWYIWLGFIA
SPIKE_BCHK5 PNFQ-EISKINTTLLNLNTELMVLSEVVKQLNESYIDLKELGNYTFYQKWPWYIWLGFIA
SPIKE_BC133 PNFA-EISKINTTLLDLSDEMAILQEVVKQLNDSYIDLKELGNYTYYNKWPWYIWLGFIA
SPIKE_BCHK4 PNFA-EISKINTTLLDLSDEMAMLQEVVKQLNDSYIDLKELGNYTYYNKWPWYVWLGFIA
: . :* : ::: :: : : : ** * *:*:.:. * *****:** :
SPIKE_BCHK9 GIVGLVLAVIMLMCMTNCCSCFKGMCDCRRCCGSYDSYDDVYPAVRVNKKRTV
SPIKE_SARS GLIAIVMVTILLCCMTSCCSCLKGACSCGSCC-KFDEDDS-EPVLKGVKLHYT
SPIKE_BCHK3 GLIAIVMVTILLCCMTSCCSCLKGACSCGSCC-KFDEDDS-EPVLKGVKLHYT
SPIKE_BC279 GLIAIVMVTILLCCMTSCCSCLKGACSCGSCC-KFDEDDS-EPVLKGVKLHYT
SPIKE_BCRP3 GLIAIVMVTILLCCMTSCCSCLKGACSCGSCC-KFDEDDS-EPVLKGVKLHYT
SPIKE_CVHN1 SFIIFLVLLFFICCCTGCGSACFS--KCHNCCDEYGGHHD-FVI---KTSHDD
SPIKE_CVHN5 LFIIFLMILFFICCCTGCGSACFS--KCHNCCDEYGGHND-FVI---KASHDD
SPIKE_CVHN2 LFIIFLMILFFICCCTGCGSACFS--KCHNCCDEYGGHND-FVI---KASHDD
SPIKE_CVRSD AGVAVCVLLFFICCCTGCGSCCFK--KCGNCCDEYGGRQA-GIVIHNISSHED
SPIKE_CVMA5 AGVAVCVLLFFICCCTGCGSCCFK--KCGNCCDEYGGHQD-SIVIHNISSHED
SPIKE_CVMJC AGVAVCVLLFFICCCTGCGSCCFR--KCGSCCDEYGGHQD-SIVIYNISAHED
SPIKE_CVM4 AGVAVCVLLFFICCCTGCGSCCFR--KCGSCCDEYGGHQD-SIVIHNISAHED
SPIKE_CVMJH AGVAVCVLLFFICCCTGCGSCCFR--KCGSCCDEYGGHQD-SIVIHNISAHED
SPIKE_CVP67 AGVAMLVLLFFICCCTGCGTSCFK--KCGGCCDDYTGHQE-FVI---KTSHDD
SPIKE_CVPIA AGVVMLVLLFFICCCTGCGTSCFK--KCGGCFDDYTGHQE-FVI---KTSHDD
SPIKE_CVHOC AGVAMLVLLFFICCCTGCGTSCFK--KCGGCCDDYTGYQE-LVI---KTSHDD
SPIKE_CVBLS AGVAMLVLLFFICCCTGCGTSCFK--KCGGCCDDYTGHQE-LVI---KTSHDD
SPIKE_CVBOK AGVAMLVLLFFICCCTGCGTSCFK--KCGGCCDDYTGHQE-LVI---KTSHDD
SPIKE_CVBEN AGVAMLVLLFFICCCTGCGTSCFK--KCGGCCDDYTGHQE-LVI---KTSHED
SPIKE_CVBLU AGVAMLVLLFFICCCTGCGTSCFK--KCGGCCDDYTGHQE-LVI---KTSHED
SPIKE_CVBM AGVAMLVLLFFICCCTGCGTSCFK--ICGGCCDDYTGHQE-LVI---KTSHDD
SPIKE_CVBQ AGVAMLVLLFFICCCTGCGTSCFK--ICGGCCDDYTGHQE-LVI---KTSHDD
SPIKE_CVBL9 AGVAMLVLLFFICCCTGCGTSCFK--ICGGCCDDYTGHQE-LVI---KTSHDD
SPIKE_CVBV AGVAMLVLLFFICCCTGCGTSCFK--ICGGCCDDYTGHQE-LVI---KTSHDD
SPIKE_CVBF AGVAMLVLLFFICCCTGCGTSCFK--KCGGCCDDYTGHQE-LVI---KTSHDD
SPIKE_CVBLY AGVAMLVLLFFICCCTGCGTSCFK--KCGGCCDDYTGHQE-LVI---KTSHDD
SPIKE_CVEMC GLVALALCVFFILCCTGCGTNCMGKLKCNRCCDRYEEYDL-EP----HKVHVH
SPIKE_BCHK5 GLVALALCVFFILCCTGCGTSCLGKLKCNRCCDSYDEYEV-E------KIHVH
SPIKE_BC133 GLVALLLCVFFLLCCTGCGTSCLGKMKCKNCCDSYEEYDV-E------KIHVH
SPIKE_BCHK4 GLVALLLCVFFLLCCTGCGTSCLGKMKCKNCCDSYEEYDV-E------KIHVH
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