CONSTRUCT { _:41318 up:source unirule:MF_00107 . _:41319 up:source unirule:MF_00107 . _:41320 up:source unirule:MF_00107 . _:41321 up:source unirule:MF_00107 . _:41322 up:source unirule:MF_00107 . _:41323 up:source unirule:MF_00107 . _:41324 up:source unirule:MF_00107 . _:41325 up:source unirule:MF_00107 . _:41326 up:source unirule:MF_00107 . _:41327 up:source unirule:MF_00107 . _:41328 up:source unirule:MF_00107 . _:41329 up:source unirule:MF_00107 . _:41330 up:source unirule:MF_00107 . _:41331 up:source unirule:MF_00107 . _:41332 up:source unirule:MF_00107 . _:41333 up:source unirule:MF_00107 . _:41334 up:source unirule:MF_00107 . _:41335 up:source unirule:MF_00107 . _:41336 up:source unirule:MF_00107 . _:41337 up:source unirule:MF_00107 . _:41338 up:source unirule:MF_00107 . _:41339 up:source unirule:MF_00107 . _:41340 up:source unirule:MF_00107 . _:41341 up:source unirule:MF_00107 . _:41342 up:source unirule:MF_00107 . _:41343 up:source unirule:MF_00107 . ?this up:annotation ?annotation2 , ?annotation3 , ?annotation5 , ?annotation6 , ?annotation7 , ?annotation8 ; up:classifiedWith GO:0008685 , GO:0019288 , keyword:414 , keyword:456 , keyword:479 ; up:recommendedName ?name0 . ?name0 up:ecName '4.6.1.12' ; up:fullName '2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase' ; up:shortName 'MECPP-synthase' , 'MECDP-synthase' , 'MECPS' ; rdf:type up:Structured_Name . ?gene1 skos:prefLabel 'ispF' . ?annotation2 a up:Function_Annotation ; rdfs:comment 'Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).' . ?annotation3 up:activity ?activity4 ; rdf:type up:Catalytic_Activity_Annotation . ?activity4 up:catalyticActivity <http://rdf.rhea-db.org/23864>; up:enzymeClass <http://purl.uniprot.org/enzyme/4.6.1.12>. ?annotation5 up:cofactor chebi:60240 ; rdf:type up:Cofactor_Annotation ; rdfs:comment 'Binds 1 divalent metal cation per subunit.' . ?annotation6 a up:Pathway_Annotation ; rdfs:comment 'Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.' . ?annotation7 a up:Subunit_Annotation ; rdfs:comment 'Homotrimer.' . ?annotation8 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the IspF family.' . ?pfs9 up:annotation ?annotation10 . ?annotation10 faldo:begin ?pfsb11 ; faldo:end ?pfse12 ; up:ligand ?ligand13 ; rdf:type up:Binding_Site_Annotation . ?pfsb11 faldo:position ?thisPositionOn14 ; rdf:type faldo:ExactPosition . ?pfse12 faldo:position ?thisPositionOn15 ; rdf:type faldo:ExactPosition . ?ligand13 rdfs:subClassOf chebi:57919 . ?pfs16 up:annotation ?annotation17 . ?annotation17 faldo:begin ?pfsb18 ; faldo:end ?pfse19 ; up:ligand ?ligand20 ; rdf:type up:Binding_Site_Annotation . ?pfsb18 faldo:position ?thisPositionOn21 ; rdf:type faldo:ExactPosition . ?pfse19 faldo:position ?thisPositionOn22 ; rdf:type faldo:ExactPosition . ?ligand20 rdfs:subClassOf chebi:57919 . ?pfs23 up:annotation ?annotation24 . ?annotation24 faldo:begin ?pfsb25 ; faldo:end ?pfse26 ; up:ligand ?ligand27 ; rdf:type up:Binding_Site_Annotation . ?pfsb25 faldo:position ?thisPositionOn28 ; rdf:type faldo:ExactPosition . ?pfse26 faldo:position ?thisPositionOn29 ; rdf:type faldo:ExactPosition . ?ligand27 rdfs:subClassOf chebi:57919 . ?pfs30 up:annotation ?annotation31 . ?annotation31 faldo:begin ?pfsb32 ; faldo:end ?pfse33 ; up:ligand ?ligand34 ; rdf:type up:Binding_Site_Annotation . ?pfsb32 faldo:position ?thisPositionOn35 ; rdf:type faldo:ExactPosition . ?pfse33 faldo:position ?thisPositionOn36 ; rdf:type faldo:ExactPosition . ?ligand34 rdfs:subClassOf chebi:57919 . ?pfs37 up:annotation ?annotation38 . ?annotation38 faldo:begin ?pfsb39 ; faldo:end ?pfse40 ; up:ligand ?ligand41 ; rdf:type up:Binding_Site_Annotation . ?pfsb39 faldo:position ?thisPositionOn42 ; rdf:type faldo:ExactPosition . ?pfse40 faldo:position ?thisPositionOn43 ; rdf:type faldo:ExactPosition . ?ligand41 rdfs:subClassOf chebi:57919 . ?pfs44 up:annotation ?annotation45 . ?annotation45 faldo:begin ?pfsb46 ; faldo:end ?pfse47 ; up:ligand ?ligand48 ; rdf:type up:Binding_Site_Annotation . ?pfsb46 faldo:position ?thisPositionOn49 ; rdf:type faldo:ExactPosition . ?pfse47 faldo:position ?thisPositionOn50 ; rdf:type faldo:ExactPosition . ?ligand48 rdfs:subClassOf chebi:57919 . ?pfs51 up:annotation ?annotation52 . ?annotation52 faldo:begin ?pfsb53 ; faldo:end ?pfse54 ; up:ligand ?ligand55 ; rdf:type up:Binding_Site_Annotation . ?pfsb53 faldo:position ?thisPositionOn56 ; rdf:type faldo:ExactPosition . ?pfse54 faldo:position ?thisPositionOn57 ; rdf:type faldo:ExactPosition . ?ligand55 rdfs:subClassOf chebi:60240 . ?pfs58 up:annotation ?annotation59 . ?annotation59 faldo:begin ?pfsb60 ; faldo:end ?pfse61 ; up:ligand ?ligand62 ; rdf:type up:Binding_Site_Annotation . ?pfsb60 faldo:position ?thisPositionOn63 ; rdf:type faldo:ExactPosition . ?pfse61 faldo:position ?thisPositionOn64 ; rdf:type faldo:ExactPosition . ?ligand62 rdfs:subClassOf chebi:60240 . ?pfs65 up:annotation ?annotation66 . ?annotation66 faldo:begin ?pfsb67 ; faldo:end ?pfse68 ; up:ligand ?ligand69 ; rdf:type up:Binding_Site_Annotation . ?pfsb67 faldo:position ?thisPositionOn70 ; rdf:type faldo:ExactPosition . ?pfse68 faldo:position ?thisPositionOn71 ; rdf:type faldo:ExactPosition . ?ligand69 rdfs:subClassOf chebi:60240 . ?pfs72 up:annotation ?annotation73 . ?annotation73 faldo:begin ?pfsb74 ; faldo:end ?pfse75 ; up:ligand ?ligand76 ; rdf:type up:Binding_Site_Annotation . ?pfsb74 faldo:position ?thisPositionOn77 ; rdf:type faldo:ExactPosition . ?pfse75 faldo:position ?thisPositionOn78 ; rdf:type faldo:ExactPosition . ?ligand76 rdfs:subClassOf chebi:57919 . ?pfs79 up:annotation ?annotation80 . ?annotation80 faldo:begin ?pfsb81 ; faldo:end ?pfse82 ; up:ligand ?ligand83 ; rdf:type up:Binding_Site_Annotation . ?pfsb81 faldo:position ?thisPositionOn84 ; rdf:type faldo:ExactPosition . ?pfse82 faldo:position ?thisPositionOn85 ; rdf:type faldo:ExactPosition . ?ligand83 rdfs:subClassOf chebi:57919 . ?pfs86 up:annotation ?annotation87 . ?annotation87 faldo:begin ?pfsb88 ; faldo:end ?pfse89 ; rdf:type up:Site_Annotation ; rdfs:comment 'Transition state stabilizer' . ?pfsb88 faldo:position ?thisPositionOn90 ; rdf:type faldo:ExactPosition . ?pfse89 faldo:position ?thisPositionOn91 ; rdf:type faldo:ExactPosition . ?pfs92 up:annotation ?annotation93 . ?annotation93 faldo:begin ?pfsb94 ; faldo:end ?pfse95 ; rdf:type up:Site_Annotation ; rdfs:comment 'Transition state stabilizer' . ?pfsb94 faldo:position ?thisPositionOn96 ; rdf:type faldo:ExactPosition . ?pfse95 faldo:position ?thisPositionOn97 ; rdf:type faldo:ExactPosition . _:41344 a rdf:Statement ; up:attribution _:41318 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:41345 a rdf:Statement ; up:attribution _:41319 ; rdf:subject ?gene1 ; rdf:predicate up:encodedBy ; rdf:object ?gene1 . _:41346 a rdf:Statement ; up:attribution _:41320 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation2 . _:41347 a rdf:Statement ; up:attribution _:41321 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation3 . _:41348 a rdf:Statement ; up:attribution _:41322 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation5 . _:41349 a rdf:Statement ; up:attribution _:41323 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation6 . _:41350 a rdf:Statement ; up:attribution _:41324 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation7 . _:41351 a rdf:Statement ; up:attribution _:41325 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation8 . _:41352 a rdf:Statement ; up:attribution _:41326 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:414 . _:41353 a rdf:Statement ; up:attribution _:41327 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:456 . _:41354 a rdf:Statement ; up:attribution _:41328 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:479 . _:41355 a rdf:Statement ; up:attribution _:41329 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0008685 . _:41356 a rdf:Statement ; up:attribution _:41330 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0019288 . _:41357 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs9 ; rdf:predicate up:annotation ; rdf:object ?annotation10 . _:41358 a rdf:Statement ; up:attribution _:41331 ; rdf:subject ?pfs9 ; rdf:predicate up:annotation ; rdf:object ?annotation10 . _:41359 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs16 ; rdf:predicate up:annotation ; rdf:object ?annotation17 . _:41360 a rdf:Statement ; up:attribution _:41332 ; rdf:subject ?pfs16 ; rdf:predicate up:annotation ; rdf:object ?annotation17 . _:41361 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs23 ; rdf:predicate up:annotation ; rdf:object ?annotation24 . _:41362 a rdf:Statement ; up:attribution _:41333 ; rdf:subject ?pfs23 ; rdf:predicate up:annotation ; rdf:object ?annotation24 . _:41363 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs30 ; rdf:predicate up:annotation ; rdf:object ?annotation31 . _:41364 a rdf:Statement ; up:attribution _:41334 ; rdf:subject ?pfs30 ; rdf:predicate up:annotation ; rdf:object ?annotation31 . _:41365 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs37 ; rdf:predicate up:annotation ; rdf:object ?annotation38 . _:41366 a rdf:Statement ; up:attribution _:41335 ; rdf:subject ?pfs37 ; rdf:predicate up:annotation ; rdf:object ?annotation38 . _:41367 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs44 ; rdf:predicate up:annotation ; rdf:object ?annotation45 . _:41368 a rdf:Statement ; up:attribution _:41336 ; rdf:subject ?pfs44 ; rdf:predicate up:annotation ; rdf:object ?annotation45 . _:41369 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs51 ; rdf:predicate up:annotation ; rdf:object ?annotation52 . _:41370 a rdf:Statement ; up:attribution _:41337 ; rdf:subject ?pfs51 ; rdf:predicate up:annotation ; rdf:object ?annotation52 . _:41371 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs58 ; rdf:predicate up:annotation ; rdf:object ?annotation59 . _:41372 a rdf:Statement ; up:attribution _:41338 ; rdf:subject ?pfs58 ; rdf:predicate up:annotation ; rdf:object ?annotation59 . _:41373 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs65 ; rdf:predicate up:annotation ; rdf:object ?annotation66 . _:41374 a rdf:Statement ; up:attribution _:41339 ; rdf:subject ?pfs65 ; rdf:predicate up:annotation ; rdf:object ?annotation66 . _:41375 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs72 ; rdf:predicate up:annotation ; rdf:object ?annotation73 . _:41376 a rdf:Statement ; up:attribution _:41340 ; rdf:subject ?pfs72 ; rdf:predicate up:annotation ; rdf:object ?annotation73 . _:41377 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs79 ; rdf:predicate up:annotation ; rdf:object ?annotation80 . _:41378 a rdf:Statement ; up:attribution _:41341 ; rdf:subject ?pfs79 ; rdf:predicate up:annotation ; rdf:object ?annotation80 . _:41379 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs86 ; rdf:predicate up:annotation ; rdf:object ?annotation87 . _:41380 a rdf:Statement ; up:attribution _:41342 ; rdf:subject ?pfs86 ; rdf:predicate up:annotation ; rdf:object ?annotation87 . _:41381 a rdf:Statement ; up:source unirule:MF_00107 ; rdf:subject ?pfs92 ; rdf:predicate up:annotation ; rdf:object ?annotation93 . _:41382 a rdf:Statement ; up:attribution _:41343 ; rdf:subject ?pfs92 ; rdf:predicate up:annotation ; rdf:object ?annotation93 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_00107 #Rule MF_00107 Created by:hamap on:2001-06-01 Modified by:crivoire on:2024-03-12 ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_00107 . ?thisOrganism rdfs:subClassOf+ taxon:2 . FILTER (! (EXISTS { ?this rdfs:seeAlso signature:MF_01520 . })) . BIND(URI(CONCAT(STR(?this), '#MF_00107a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_00107a2')) AS ?annotation2) . BIND(URI(CONCAT(STR(?this), '#MF_00107a3')) AS ?annotation3) . BIND(URI(CONCAT(STR(?this), '#MF_00107a5')) AS ?annotation5) . BIND(URI(CONCAT(STR(?this), '#MF_00107a6')) AS ?annotation6) . BIND(URI(CONCAT(STR(?this), '#MF_00107a7')) AS ?annotation7) . BIND(URI(CONCAT(STR(?this), '#MF_00107a8')) AS ?annotation8) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch102 faldo:location ?templateMotifSequenceMatchRegionP62617103 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617105 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_0010798 . ?templateMotifSequenceMatchRegionP62617103 faldo:begin ?templateMotifSequenceMatchBeginP62617104 . ?templateMotifSequenceMatchBeginP62617104 faldo:position ?templateMotifSequenceMatchBeginPositionP6261799 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617105 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch106 faldo:location ?targetMotifMatchRegionMatch107 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107109 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107100 . ?targetMotifMatchRegionMatch107 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107108 . ?targetMotifMatchRegionMatchBeginMF_00107108 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107101 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107109 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_0010798, 1, (STRLEN(?templateMotifCigarP62617MF_0010798) - STRLEN(REPLACE(?templateMotifCigarP62617MF_0010798, CONCAT('^(?:-*[^-]){', STR(((8 - ?templateMotifSequenceMatchBeginPositionP6261799) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1110) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107100, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107100) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107100, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1110), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107100, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107100) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107100, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1110), '}'), '')))), '[^-]', ''))) AS ?step2111) . BIND(((?step2111 + ?targetMotifMatchRegionMatchBeginPositionMF_00107101) - 1) AS ?thisPositionOn14) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_0010798, 1, (STRLEN(?templateMotifCigarP62617MF_0010798) - STRLEN(REPLACE(?templateMotifCigarP62617MF_0010798, CONCAT('^(?:-*[^-]){', STR(((10 - ?templateMotifSequenceMatchBeginPositionP6261799) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1112) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107100, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107100) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107100, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1112), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107100, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107100) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107100, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1112), '}'), '')))), '[^-]', ''))) AS ?step2113) . BIND(((?step2113 + ?targetMotifMatchRegionMatchBeginPositionMF_00107101) - 1) AS ?thisPositionOn15) . BIND(?this AS ?pfs1t114) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn14))) AS ?pfsb11) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfse12) . FILTER (REGEX('D[ARNDCQEGHILKMFPSTWYVBZJUOX]H', SUBSTR(?thisSequenceValue, ?thisPositionOn14, (?thisPositionOn15 - ?thisPositionOn14)))) . BIND(URI(CONCAT(STR(?this), '#MF_00107a10')) AS ?annotation10) . BIND(?this AS ?pfs9) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch119 faldo:location ?templateMotifSequenceMatchRegionP62617120 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617122 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107115 . ?templateMotifSequenceMatchRegionP62617120 faldo:begin ?templateMotifSequenceMatchBeginP62617121 . ?templateMotifSequenceMatchBeginP62617121 faldo:position ?templateMotifSequenceMatchBeginPositionP62617116 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617122 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch123 faldo:location ?targetMotifMatchRegionMatch124 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107126 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107117 . ?targetMotifMatchRegionMatch124 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107125 . ?targetMotifMatchRegionMatchBeginMF_00107125 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107118 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107126 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107115, 1, (STRLEN(?templateMotifCigarP62617MF_00107115) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107115, CONCAT('^(?:-*[^-]){', STR(((34 - ?templateMotifSequenceMatchBeginPositionP62617116) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1127) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107117, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107117) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107117, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1127), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107117, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107117) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107117, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1127), '}'), '')))), '[^-]', ''))) AS ?step2128) . BIND(((?step2128 + ?targetMotifMatchRegionMatchBeginPositionMF_00107118) - 1) AS ?thisPositionOn21) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107115, 1, (STRLEN(?templateMotifCigarP62617MF_00107115) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107115, CONCAT('^(?:-*[^-]){', STR(((35 - ?templateMotifSequenceMatchBeginPositionP62617116) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1129) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107117, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107117) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107117, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1129), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107117, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107117) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107117, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1129), '}'), '')))), '[^-]', ''))) AS ?step2130) . BIND(((?step2130 + ?targetMotifMatchRegionMatchBeginPositionMF_00107118) - 1) AS ?thisPositionOn22) . BIND(?this AS ?pfs1t131) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfsb18) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfse19) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn21, (?thisPositionOn22 - ?thisPositionOn21)) = 'HS')) . BIND(URI(CONCAT(STR(?this), '#MF_00107a17')) AS ?annotation17) . BIND(?this AS ?pfs16) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch136 faldo:location ?templateMotifSequenceMatchRegionP62617137 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617139 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107132 . ?templateMotifSequenceMatchRegionP62617137 faldo:begin ?templateMotifSequenceMatchBeginP62617138 . ?templateMotifSequenceMatchBeginP62617138 faldo:position ?templateMotifSequenceMatchBeginPositionP62617133 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617139 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch140 faldo:location ?targetMotifMatchRegionMatch141 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107143 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107134 . ?targetMotifMatchRegionMatch141 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107142 . ?targetMotifMatchRegionMatchBeginMF_00107142 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107135 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107143 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107132, 1, (STRLEN(?templateMotifCigarP62617MF_00107132) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107132, CONCAT('^(?:-*[^-]){', STR(((56 - ?templateMotifSequenceMatchBeginPositionP62617133) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1144) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107134, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107134) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107134, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1144), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107134, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107134) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107134, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1144), '}'), '')))), '[^-]', ''))) AS ?step2145) . BIND(((?step2145 + ?targetMotifMatchRegionMatchBeginPositionMF_00107135) - 1) AS ?thisPositionOn28) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107132, 1, (STRLEN(?templateMotifCigarP62617MF_00107132) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107132, CONCAT('^(?:-*[^-]){', STR(((58 - ?templateMotifSequenceMatchBeginPositionP62617133) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1146) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107134, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107134) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107134, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1146), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107134, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107134) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107134, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1146), '}'), '')))), '[^-]', ''))) AS ?step2147) . BIND(((?step2147 + ?targetMotifMatchRegionMatchBeginPositionMF_00107135) - 1) AS ?thisPositionOn29) . BIND(?this AS ?pfs1t148) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfsb25) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn29))) AS ?pfse26) . FILTER (REGEX('[DNEK][IVL][GA]', SUBSTR(?thisSequenceValue, ?thisPositionOn28, (?thisPositionOn29 - ?thisPositionOn28)))) . BIND(URI(CONCAT(STR(?this), '#MF_00107a24')) AS ?annotation24) . BIND(?this AS ?pfs23) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch153 faldo:location ?templateMotifSequenceMatchRegionP62617154 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617156 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107149 . ?templateMotifSequenceMatchRegionP62617154 faldo:begin ?templateMotifSequenceMatchBeginP62617155 . ?templateMotifSequenceMatchBeginP62617155 faldo:position ?templateMotifSequenceMatchBeginPositionP62617150 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617156 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch157 faldo:location ?targetMotifMatchRegionMatch158 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107160 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107151 . ?targetMotifMatchRegionMatch158 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107159 . ?targetMotifMatchRegionMatchBeginMF_00107159 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107152 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107160 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107149, 1, (STRLEN(?templateMotifCigarP62617MF_00107149) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107149, CONCAT('^(?:-*[^-]){', STR(((61 - ?templateMotifSequenceMatchBeginPositionP62617150) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1161) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107151, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107151) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107151, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1161), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107151, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107151) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107151, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1161), '}'), '')))), '[^-]', ''))) AS ?step2162) . BIND(((?step2162 + ?targetMotifMatchRegionMatchBeginPositionMF_00107152) - 1) AS ?thisPositionOn35) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107149, 1, (STRLEN(?templateMotifCigarP62617MF_00107149) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107149, CONCAT('^(?:-*[^-]){', STR(((65 - ?templateMotifSequenceMatchBeginPositionP62617150) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1163) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107151, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107151) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107151, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1163), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107151, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107151) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107151, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1163), '}'), '')))), '[^-]', ''))) AS ?step2164) . BIND(((?step2164 + ?targetMotifMatchRegionMatchBeginPositionMF_00107152) - 1) AS ?thisPositionOn36) . BIND(?this AS ?pfs1t165) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn35))) AS ?pfsb32) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn36))) AS ?pfse33) . FILTER (REGEX('F[ARNDCQEGHILKMFPSTWYVBZJUOX][DNEQ][ARNDCQEGHILKMFPSTWYVBZJUOX][DNEQ]', SUBSTR(?thisSequenceValue, ?thisPositionOn35, (?thisPositionOn36 - ?thisPositionOn35)))) . BIND(URI(CONCAT(STR(?this), '#MF_00107a31')) AS ?annotation31) . BIND(?this AS ?pfs30) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch170 faldo:location ?templateMotifSequenceMatchRegionP62617171 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617173 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107166 . ?templateMotifSequenceMatchRegionP62617171 faldo:begin ?templateMotifSequenceMatchBeginP62617172 . ?templateMotifSequenceMatchBeginP62617172 faldo:position ?templateMotifSequenceMatchBeginPositionP62617167 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617173 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch174 faldo:location ?targetMotifMatchRegionMatch175 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107177 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107168 . ?targetMotifMatchRegionMatch175 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107176 . ?targetMotifMatchRegionMatchBeginMF_00107176 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107169 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107177 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107166, 1, (STRLEN(?templateMotifCigarP62617MF_00107166) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107166, CONCAT('^(?:-*[^-]){', STR(((100 - ?templateMotifSequenceMatchBeginPositionP62617167) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1178) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107168, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107168) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107168, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1178), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107168, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107168) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107168, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1178), '}'), '')))), '[^-]', ''))) AS ?step2179) . BIND(((?step2179 + ?targetMotifMatchRegionMatchBeginPositionMF_00107169) - 1) AS ?thisPositionOn42) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107166, 1, (STRLEN(?templateMotifCigarP62617MF_00107166) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107166, CONCAT('^(?:-*[^-]){', STR(((106 - ?templateMotifSequenceMatchBeginPositionP62617167) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1180) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107168, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107168) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107168, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1180), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107168, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107168) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107168, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1180), '}'), '')))), '[^-]', ''))) AS ?step2181) . BIND(((?step2181 + ?targetMotifMatchRegionMatchBeginPositionMF_00107169) - 1) AS ?thisPositionOn43) . BIND(?this AS ?pfs1t182) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn42))) AS ?pfsb39) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn43))) AS ?pfse40) . FILTER (REGEX('[ALVI][ARNDCQEGHILKMFPSTWYVBZJUOX]{2)P[KNR]M[LAGI]', SUBSTR(?thisSequenceValue, ?thisPositionOn42, (?thisPositionOn43 - ?thisPositionOn42)))) . BIND(URI(CONCAT(STR(?this), '#MF_00107a38')) AS ?annotation38) . BIND(?this AS ?pfs37) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch187 faldo:location ?templateMotifSequenceMatchRegionP62617188 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617190 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107183 . ?templateMotifSequenceMatchRegionP62617188 faldo:begin ?templateMotifSequenceMatchBeginP62617189 . ?templateMotifSequenceMatchBeginP62617189 faldo:position ?templateMotifSequenceMatchBeginPositionP62617184 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617190 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch191 faldo:location ?targetMotifMatchRegionMatch192 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107194 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107185 . ?targetMotifMatchRegionMatch192 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107193 . ?targetMotifMatchRegionMatchBeginMF_00107193 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107186 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107194 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107183, 1, (STRLEN(?templateMotifCigarP62617MF_00107183) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107183, CONCAT('^(?:-*[^-]){', STR(((132 - ?templateMotifSequenceMatchBeginPositionP62617184) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1195) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107185, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107185) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107185, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1195), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107185, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107185) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107185, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1195), '}'), '')))), '[^-]', ''))) AS ?step2196) . BIND(((?step2196 + ?targetMotifMatchRegionMatchBeginPositionMF_00107186) - 1) AS ?thisPositionOn49) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107183, 1, (STRLEN(?templateMotifCigarP62617MF_00107183) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107183, CONCAT('^(?:-*[^-]){', STR(((135 - ?templateMotifSequenceMatchBeginPositionP62617184) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1197) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107185, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107185) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107185, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1197), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107185, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107185) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107185, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1197), '}'), '')))), '[^-]', ''))) AS ?step2198) . BIND(((?step2198 + ?targetMotifMatchRegionMatchBeginPositionMF_00107186) - 1) AS ?thisPositionOn50) . BIND(?this AS ?pfs1t199) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn49))) AS ?pfsb46) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn50))) AS ?pfse47) . FILTER (REGEX('[TS][TS][ARNDCQEGHILKMFPSTWYVBZJUOX][EDN]', SUBSTR(?thisSequenceValue, ?thisPositionOn49, (?thisPositionOn50 - ?thisPositionOn49)))) . BIND(URI(CONCAT(STR(?this), '#MF_00107a45')) AS ?annotation45) . BIND(?this AS ?pfs44) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch204 faldo:location ?templateMotifSequenceMatchRegionP62617205 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617207 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107200 . ?templateMotifSequenceMatchRegionP62617205 faldo:begin ?templateMotifSequenceMatchBeginP62617206 . ?templateMotifSequenceMatchBeginP62617206 faldo:position ?templateMotifSequenceMatchBeginPositionP62617201 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617207 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch208 faldo:location ?targetMotifMatchRegionMatch209 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107211 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107202 . ?targetMotifMatchRegionMatch209 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107210 . ?targetMotifMatchRegionMatchBeginMF_00107210 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107203 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107211 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107200, 1, (STRLEN(?templateMotifCigarP62617MF_00107200) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107200, CONCAT('^(?:-*[^-]){', STR(((8 - ?templateMotifSequenceMatchBeginPositionP62617201) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1212) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107202, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107202) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107202, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1212), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107202, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107202) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107202, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1212), '}'), '')))), '[^-]', ''))) AS ?step2213) . BIND(((?step2213 + ?targetMotifMatchRegionMatchBeginPositionMF_00107203) - 1) AS ?thisPositionOn56) . BIND(?thisPositionOn56 AS ?thisPositionOn57) . BIND(?this AS ?pfs1t214) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn56))) AS ?pfsb53) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn57))) AS ?pfse54) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn56, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_00107a52')) AS ?annotation52) . BIND(?this AS ?pfs51) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch219 faldo:location ?templateMotifSequenceMatchRegionP62617220 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617222 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107215 . ?templateMotifSequenceMatchRegionP62617220 faldo:begin ?templateMotifSequenceMatchBeginP62617221 . ?templateMotifSequenceMatchBeginP62617221 faldo:position ?templateMotifSequenceMatchBeginPositionP62617216 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617222 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch223 faldo:location ?targetMotifMatchRegionMatch224 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107226 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107217 . ?targetMotifMatchRegionMatch224 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107225 . ?targetMotifMatchRegionMatchBeginMF_00107225 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107218 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107226 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107215, 1, (STRLEN(?templateMotifCigarP62617MF_00107215) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107215, CONCAT('^(?:-*[^-]){', STR(((10 - ?templateMotifSequenceMatchBeginPositionP62617216) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1227) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107217, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107217) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107217, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1227), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107217, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107217) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107217, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1227), '}'), '')))), '[^-]', ''))) AS ?step2228) . BIND(((?step2228 + ?targetMotifMatchRegionMatchBeginPositionMF_00107218) - 1) AS ?thisPositionOn63) . BIND(?thisPositionOn63 AS ?thisPositionOn64) . BIND(?this AS ?pfs1t229) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn63))) AS ?pfsb60) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn64))) AS ?pfse61) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn63, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_00107a59')) AS ?annotation59) . BIND(?this AS ?pfs58) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch234 faldo:location ?templateMotifSequenceMatchRegionP62617235 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617237 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107230 . ?templateMotifSequenceMatchRegionP62617235 faldo:begin ?templateMotifSequenceMatchBeginP62617236 . ?templateMotifSequenceMatchBeginP62617236 faldo:position ?templateMotifSequenceMatchBeginPositionP62617231 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617237 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch238 faldo:location ?targetMotifMatchRegionMatch239 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107241 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107232 . ?targetMotifMatchRegionMatch239 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107240 . ?targetMotifMatchRegionMatchBeginMF_00107240 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107233 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107241 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107230, 1, (STRLEN(?templateMotifCigarP62617MF_00107230) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107230, CONCAT('^(?:-*[^-]){', STR(((42 - ?templateMotifSequenceMatchBeginPositionP62617231) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1242) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107232, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107232) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107232, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1242), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107232, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107232) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107232, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1242), '}'), '')))), '[^-]', ''))) AS ?step2243) . BIND(((?step2243 + ?targetMotifMatchRegionMatchBeginPositionMF_00107233) - 1) AS ?thisPositionOn70) . BIND(?thisPositionOn70 AS ?thisPositionOn71) . BIND(?this AS ?pfs1t244) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn70))) AS ?pfsb67) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn71))) AS ?pfse68) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn70, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_00107a66')) AS ?annotation66) . BIND(?this AS ?pfs65) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch249 faldo:location ?templateMotifSequenceMatchRegionP62617250 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617252 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107245 . ?templateMotifSequenceMatchRegionP62617250 faldo:begin ?templateMotifSequenceMatchBeginP62617251 . ?templateMotifSequenceMatchBeginP62617251 faldo:position ?templateMotifSequenceMatchBeginPositionP62617246 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617252 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch253 faldo:location ?targetMotifMatchRegionMatch254 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107256 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107247 . ?targetMotifMatchRegionMatch254 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107255 . ?targetMotifMatchRegionMatchBeginMF_00107255 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107248 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107256 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107245, 1, (STRLEN(?templateMotifCigarP62617MF_00107245) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107245, CONCAT('^(?:-*[^-]){', STR(((139 - ?templateMotifSequenceMatchBeginPositionP62617246) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1257) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107247, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107247) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107247, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1257), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107247, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107247) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107247, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1257), '}'), '')))), '[^-]', ''))) AS ?step2258) . BIND(((?step2258 + ?targetMotifMatchRegionMatchBeginPositionMF_00107248) - 1) AS ?thisPositionOn77) . BIND(?thisPositionOn77 AS ?thisPositionOn78) . BIND(?this AS ?pfs1t259) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn77))) AS ?pfsb74) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn78))) AS ?pfse75) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn77, 1) = 'F')) . BIND(URI(CONCAT(STR(?this), '#MF_00107a73')) AS ?annotation73) . BIND(?this AS ?pfs72) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch264 faldo:location ?templateMotifSequenceMatchRegionP62617265 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617267 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107260 . ?templateMotifSequenceMatchRegionP62617265 faldo:begin ?templateMotifSequenceMatchBeginP62617266 . ?templateMotifSequenceMatchBeginP62617266 faldo:position ?templateMotifSequenceMatchBeginPositionP62617261 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617267 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch268 faldo:location ?targetMotifMatchRegionMatch269 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107271 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107262 . ?targetMotifMatchRegionMatch269 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107270 . ?targetMotifMatchRegionMatchBeginMF_00107270 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107263 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107271 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107260, 1, (STRLEN(?templateMotifCigarP62617MF_00107260) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107260, CONCAT('^(?:-*[^-]){', STR(((142 - ?templateMotifSequenceMatchBeginPositionP62617261) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1272) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107262, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107262) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107262, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1272), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107262, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107262) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107262, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1272), '}'), '')))), '[^-]', ''))) AS ?step2273) . BIND(((?step2273 + ?targetMotifMatchRegionMatchBeginPositionMF_00107263) - 1) AS ?thisPositionOn84) . BIND(?thisPositionOn84 AS ?thisPositionOn85) . BIND(?this AS ?pfs1t274) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn84))) AS ?pfsb81) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn85))) AS ?pfse82) . FILTER (REGEX('[RHK]', SUBSTR(?thisSequenceValue, ?thisPositionOn84, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_00107a80')) AS ?annotation80) . BIND(?this AS ?pfs79) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch279 faldo:location ?templateMotifSequenceMatchRegionP62617280 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617282 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107275 . ?templateMotifSequenceMatchRegionP62617280 faldo:begin ?templateMotifSequenceMatchBeginP62617281 . ?templateMotifSequenceMatchBeginP62617281 faldo:position ?templateMotifSequenceMatchBeginPositionP62617276 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617282 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch283 faldo:location ?targetMotifMatchRegionMatch284 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107286 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107277 . ?targetMotifMatchRegionMatch284 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107285 . ?targetMotifMatchRegionMatchBeginMF_00107285 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107278 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107286 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107275, 1, (STRLEN(?templateMotifCigarP62617MF_00107275) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107275, CONCAT('^(?:-*[^-]){', STR(((34 - ?templateMotifSequenceMatchBeginPositionP62617276) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1287) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107277, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107277) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107277, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1287), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107277, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107277) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107277, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1287), '}'), '')))), '[^-]', ''))) AS ?step2288) . BIND(((?step2288 + ?targetMotifMatchRegionMatchBeginPositionMF_00107278) - 1) AS ?thisPositionOn90) . BIND(?thisPositionOn90 AS ?thisPositionOn91) . BIND(?this AS ?pfs1t289) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn90))) AS ?pfsb88) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn91))) AS ?pfse89) . FILTER (REGEX('[HDN]', SUBSTR(?thisSequenceValue, ?thisPositionOn90, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_00107a87')) AS ?annotation87) . BIND(?this AS ?pfs86) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch294 faldo:location ?templateMotifSequenceMatchRegionP62617295 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP62617297 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP62617MF_00107290 . ?templateMotifSequenceMatchRegionP62617295 faldo:begin ?templateMotifSequenceMatchBeginP62617296 . ?templateMotifSequenceMatchBeginP62617296 faldo:position ?templateMotifSequenceMatchBeginPositionP62617291 ; faldo:reference isoform:P62617-1 . ?templateMotifSequenceProfileAlignmentOperationP62617297 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . ?targetMotifMatch298 faldo:location ?targetMotifMatchRegionMatch299 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00107301 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP62617MF_00107292 . ?targetMotifMatchRegionMatch299 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00107300 . ?targetMotifMatchRegionMatchBeginMF_00107300 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00107293 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00107301 edam:has_input signature:MF_00107 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP62617MF_00107290, 1, (STRLEN(?templateMotifCigarP62617MF_00107290) - STRLEN(REPLACE(?templateMotifCigarP62617MF_00107290, CONCAT('^(?:-*[^-]){', STR(((133 - ?templateMotifSequenceMatchBeginPositionP62617291) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1302) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP62617MF_00107292, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107292) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107292, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1302), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP62617MF_00107292, 1, (STRLEN(?targetMotifMatchCigarP62617MF_00107292) - STRLEN(REPLACE(?targetMotifMatchCigarP62617MF_00107292, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1302), '}'), '')))), '[^-]', ''))) AS ?step2303) . BIND(((?step2303 + ?targetMotifMatchRegionMatchBeginPositionMF_00107293) - 1) AS ?thisPositionOn96) . BIND(?thisPositionOn96 AS ?thisPositionOn97) . BIND(?this AS ?pfs1t304) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn96))) AS ?pfsb94) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn97))) AS ?pfse95) . FILTER (REGEX('[TS]', SUBSTR(?thisSequenceValue, ?thisPositionOn96, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_00107a93')) AS ?annotation93) . BIND(?this AS ?pfs92) . } }