CONSTRUCT { _:446317 up:source unirule:MF_01274 . _:446318 up:source unirule:MF_01274 . _:446319 up:source unirule:MF_01274 . _:446320 up:source unirule:MF_01274 . _:446321 up:source unirule:MF_01274 . _:446322 up:source unirule:MF_01274 . _:446323 up:source unirule:MF_01274 . _:446324 up:source unirule:MF_01274 . _:446325 up:source unirule:MF_01274 . _:446326 up:source unirule:MF_01274 . _:446327 up:source unirule:MF_01274 . _:446328 up:source unirule:MF_01274 . _:446329 up:source unirule:MF_01274 . _:446330 up:source unirule:MF_01274 . _:446331 up:source unirule:MF_01274 . _:446332 up:source unirule:MF_01274 . _:446333 up:source unirule:MF_01274 . _:446334 up:source unirule:MF_01274 . _:446335 up:source unirule:MF_01274 . _:446336 up:source unirule:MF_01274 . _:446337 up:source unirule:MF_01274 . _:446338 up:source unirule:MF_01274 . _:446339 up:source unirule:MF_01274 . _:446340 up:source unirule:MF_01274 . _:446341 up:source unirule:MF_01274 . _:446342 up:source unirule:MF_01274 . _:446343 up:source unirule:MF_01274 . _:446344 up:source unirule:MF_01274 . _:446345 up:source unirule:MF_01274 . _:446346 up:source unirule:MF_01274 . _:446347 up:source unirule:MF_01274 . ?this up:alternativeName ?name1 , ?name2 ; up:annotation ?annotation4 , ?annotation5 , ?annotation7 , ?annotation8 , ?annotation9 , ?annotation10 , ?annotation12 ; up:classifiedWith GO:0004594 , GO:0005524 , GO:0005737 , GO:0015937 , keyword:173 , keyword:418 , keyword:547 , keyword:630 , keyword:67 , keyword:808 , keyword:963 ; up:recommendedName ?name0 . ?name0 up:ecName '2.7.1.33' ; up:fullName 'Type III pantothenate kinase' ; rdf:type up:Structured_Name . ?name1 up:fullName 'PanK-III' ; rdf:type up:Structured_Name . ?name2 up:fullName 'Pantothenic acid kinase' ; rdf:type up:Structured_Name . ?gene3 skos:prefLabel 'coaX' . ?annotation4 a up:Function_Annotation ; rdfs:comment 'Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.' . ?annotation5 up:activity ?activity6 ; rdf:type up:Catalytic_Activity_Annotation . ?activity6 up:catalyticActivity <http://rdf.rhea-db.org/16373>; up:enzymeClass <http://purl.uniprot.org/enzyme/2.7.1.33>. ?annotation7 up:cofactor chebi:28938 , chebi:29103 ; rdf:type up:Cofactor_Annotation ; rdfs:comment 'A monovalent cation. Ammonium or potassium.' . ?annotation8 a up:Pathway_Annotation ; rdfs:comment 'Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.' . ?annotation9 a up:Subunit_Annotation ; rdfs:comment 'Homodimer.' . ?annotation10 a up:Subcellular_Location_Annotation . ?annotation10li11 up:cellularComponent <http://purl.uniprot.org/locations/null>. ?annotation12 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the type III pantothenate kinase family.' . ?case13 up:classifiedWith GO:0043169 , keyword:479 . ?pfs14 up:annotation ?annotation15 . ?annotation15 faldo:begin ?pfsb16 ; faldo:end ?pfse17 ; up:ligand ?ligand18 ; rdf:type up:Binding_Site_Annotation . ?pfsb16 faldo:position ?thisPositionOn19 ; rdf:type faldo:ExactPosition . ?pfse17 faldo:position ?thisPositionOn20 ; rdf:type faldo:ExactPosition . ?ligand18 rdfs:subClassOf chebi:29103 . ?pfs21 up:annotation ?annotation22 . ?annotation22 faldo:begin ?pfsb23 ; faldo:end ?pfse24 ; up:ligand ?ligand25 ; rdf:type up:Binding_Site_Annotation . ?pfsb23 faldo:position ?thisPositionOn26 ; rdf:type faldo:ExactPosition . ?pfse24 faldo:position ?thisPositionOn27 ; rdf:type faldo:ExactPosition . ?ligand25 rdfs:subClassOf chebi:30616 . ?pfs28 up:annotation ?annotation29 . ?annotation29 faldo:begin ?pfsb30 ; faldo:end ?pfse31 ; up:ligand ?ligand32 ; rdf:type up:Binding_Site_Annotation . ?pfsb30 faldo:position ?thisPositionOn34 ; rdf:type faldo:ExactPosition . ?pfse31 faldo:position ?thisPositionOn35 ; rdf:type faldo:ExactPosition . ?ligand32 rdfs:subClassOf ?molecule33 . ?molecule33 rdfs:label 'substrate' . ?pfs36 up:annotation ?annotation37 . ?annotation37 faldo:begin ?pfsb38 ; faldo:end ?pfse39 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Proton acceptor' . ?pfsb38 faldo:position ?thisPositionOn40 ; rdf:type faldo:ExactPosition . ?pfse39 faldo:position ?thisPositionOn41 ; rdf:type faldo:ExactPosition . ?pfs42 up:annotation ?annotation43 . ?annotation43 faldo:begin ?pfsb44 ; faldo:end ?pfse45 ; up:ligand ?ligand46 ; rdf:type up:Binding_Site_Annotation . ?pfsb44 faldo:position ?thisPositionOn48 ; rdf:type faldo:ExactPosition . ?pfse45 faldo:position ?thisPositionOn49 ; rdf:type faldo:ExactPosition . ?ligand46 rdfs:subClassOf ?molecule47 . ?molecule47 rdfs:label 'substrate' . ?pfs50 up:annotation ?annotation51 . ?annotation51 faldo:begin ?pfsb52 ; faldo:end ?pfse53 ; up:ligand ?ligand54 ; rdf:type up:Binding_Site_Annotation . ?pfsb52 faldo:position ?thisPositionOn55 ; rdf:type faldo:ExactPosition . ?pfse53 faldo:position ?thisPositionOn56 ; rdf:type faldo:ExactPosition . ?ligand54 rdfs:subClassOf chebi:30616 . ?pfs57 up:annotation ?annotation58 . ?annotation58 faldo:begin ?pfsb59 ; faldo:end ?pfse60 ; up:ligand ?ligand61 ; rdf:type up:Binding_Site_Annotation . ?pfsb59 faldo:position ?thisPositionOn63 ; rdf:type faldo:ExactPosition . ?pfse60 faldo:position ?thisPositionOn64 ; rdf:type faldo:ExactPosition . ?ligand61 rdfs:subClassOf ?molecule62 . ?molecule62 rdfs:label 'substrate' . _:446348 a rdf:Statement ; up:attribution _:446317 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:446349 a rdf:Statement ; up:attribution _:446318 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name1 . _:446350 a rdf:Statement ; up:attribution _:446319 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name2 . _:446351 a rdf:Statement ; up:attribution _:446320 ; rdf:subject ?gene3 ; rdf:predicate up:encodedBy ; rdf:object ?gene3 . _:446352 a rdf:Statement ; up:attribution _:446321 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation4 . _:446353 a rdf:Statement ; up:attribution _:446322 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation5 . _:446354 a rdf:Statement ; up:attribution _:446323 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation7 . _:446355 a rdf:Statement ; up:attribution _:446324 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation8 . _:446356 a rdf:Statement ; up:attribution _:446325 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation9 . _:446357 a rdf:Statement ; up:attribution _:446326 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation10 . _:446358 a rdf:Statement ; up:attribution _:446327 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:446359 a rdf:Statement ; up:attribution _:446328 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:963 . _:446360 a rdf:Statement ; up:attribution _:446329 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:67 . _:446361 a rdf:Statement ; up:attribution _:446330 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:173 . _:446362 a rdf:Statement ; up:attribution _:446331 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:418 . _:446363 a rdf:Statement ; up:attribution _:446332 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:547 . _:446364 a rdf:Statement ; up:attribution _:446333 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:808 . _:446365 a rdf:Statement ; up:attribution _:446334 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:630 . _:446366 a rdf:Statement ; up:attribution _:446335 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0005524 . _:446367 a rdf:Statement ; up:attribution _:446336 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0004594 . _:446368 a rdf:Statement ; up:attribution _:446337 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0015937 . _:446369 a rdf:Statement ; up:attribution _:446338 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0005737 . _:446370 a rdf:Statement ; up:attribution _:446339 ; rdf:subject ?case13 ; rdf:predicate up:classifiedWith ; rdf:object keyword:479 . _:446371 a rdf:Statement ; up:attribution _:446340 ; rdf:subject ?case13 ; rdf:predicate up:classifiedWith ; rdf:object GO:0043169 . _:446372 a rdf:Statement ; up:source unirule:MF_01274 ; rdf:subject ?pfs14 ; rdf:predicate up:annotation ; rdf:object ?annotation15 . _:446373 a rdf:Statement ; up:attribution _:446341 ; rdf:subject ?pfs14 ; rdf:predicate up:annotation ; rdf:object ?annotation15 . _:446374 a rdf:Statement ; up:source unirule:MF_01274 ; rdf:subject ?pfs21 ; rdf:predicate up:annotation ; rdf:object ?annotation22 . _:446375 a rdf:Statement ; up:attribution _:446342 ; rdf:subject ?pfs21 ; rdf:predicate up:annotation ; rdf:object ?annotation22 . _:446376 a rdf:Statement ; up:source unirule:MF_01274 ; rdf:subject ?pfs28 ; rdf:predicate up:annotation ; rdf:object ?annotation29 . _:446377 a rdf:Statement ; up:attribution _:446343 ; rdf:subject ?pfs28 ; rdf:predicate up:annotation ; rdf:object ?annotation29 . _:446378 a rdf:Statement ; up:source unirule:MF_01274 ; rdf:subject ?pfs36 ; rdf:predicate up:annotation ; rdf:object ?annotation37 . _:446379 a rdf:Statement ; up:attribution _:446344 ; rdf:subject ?pfs36 ; rdf:predicate up:annotation ; rdf:object ?annotation37 . _:446380 a rdf:Statement ; up:source unirule:MF_01274 ; rdf:subject ?pfs42 ; rdf:predicate up:annotation ; rdf:object ?annotation43 . _:446381 a rdf:Statement ; up:attribution _:446345 ; rdf:subject ?pfs42 ; rdf:predicate up:annotation ; rdf:object ?annotation43 . _:446382 a rdf:Statement ; up:source unirule:MF_01274 ; rdf:subject ?pfs50 ; rdf:predicate up:annotation ; rdf:object ?annotation51 . _:446383 a rdf:Statement ; up:attribution _:446346 ; rdf:subject ?pfs50 ; rdf:predicate up:annotation ; rdf:object ?annotation51 . _:446384 a rdf:Statement ; up:source unirule:MF_01274 ; rdf:subject ?pfs57 ; rdf:predicate up:annotation ; rdf:object ?annotation58 . _:446385 a rdf:Statement ; up:attribution _:446347 ; rdf:subject ?pfs57 ; rdf:predicate up:annotation ; rdf:object ?annotation58 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_01274 #Rule MF_01274 Created by:coudert on:2006-11-21 Modified by:ecastro on:2023-06-01 ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_01274 . ?thisOrganism rdfs:subClassOf+ taxon:2 . BIND(URI(CONCAT(STR(?this), '#MF_01274a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_01274a1')) AS ?name1) . BIND(URI(CONCAT(STR(?this), '#MF_01274a2')) AS ?name2) . BIND(URI(CONCAT(STR(?this), '#MF_01274a4')) AS ?annotation4) . BIND(URI(CONCAT(STR(?this), '#MF_01274a5')) AS ?annotation5) . BIND(URI(CONCAT(STR(?this), '#MF_01274a7')) AS ?annotation7) . BIND(URI(CONCAT(STR(?this), '#MF_01274a8')) AS ?annotation8) . BIND(URI(CONCAT(STR(?this), '#MF_01274a9')) AS ?annotation9) . BIND(URI(CONCAT(STR(?this), '#MF_01274a10')) AS ?annotation10) . BIND(URI(CONCAT(STR(?this), '#MF_01274a12')) AS ?annotation12) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch69 faldo:location ?templateMotifSequenceMatchRegionQ9HWC170 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9HWC172 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9HWC1MF_0127465 . ?templateMotifSequenceMatchRegionQ9HWC170 faldo:begin ?templateMotifSequenceMatchBeginQ9HWC171 . ?templateMotifSequenceMatchBeginQ9HWC171 faldo:position ?templateMotifSequenceMatchBeginPositionQ9HWC166 ; faldo:reference isoform:Q9HWC1-1 . ?templateMotifSequenceProfileAlignmentOperationQ9HWC172 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . ?targetMotifMatch73 faldo:location ?targetMotifMatchRegionMatch74 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0127476 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9HWC1MF_0127467 . ?targetMotifMatchRegionMatch74 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0127475 . ?targetMotifMatchRegionMatchBeginMF_0127475 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0127468 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0127476 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . BIND(?this AS ?tagFT_4) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_0127465, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_0127465) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_0127465, CONCAT('^(?:-*[^-]){', STR(((121 - ?templateMotifSequenceMatchBeginPositionQ9HWC166) + 1)), '}'), '')))), '[a-z]', '')) AS ?step177) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127467, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127467) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127467, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step177), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127467, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127467) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127467, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step177), '}'), '')))), '[^-]', ''))) AS ?step278) . BIND(((?step278 + ?targetMotifMatchRegionMatchBeginPositionMF_0127468) - 1) AS ?thisPositionOn19) . BIND(?thisPositionOn19 AS ?thisPositionOn20) . BIND(?this AS ?pfs1t79) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn19))) AS ?pfsb16) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn20))) AS ?pfse17) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn19, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_01274a15')) AS ?annotation15) . BIND(?this AS ?pfs14) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch84 faldo:location ?templateMotifSequenceMatchRegionQ9HWC185 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9HWC187 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9HWC1MF_0127480 . ?templateMotifSequenceMatchRegionQ9HWC185 faldo:begin ?templateMotifSequenceMatchBeginQ9HWC186 . ?templateMotifSequenceMatchBeginQ9HWC186 faldo:position ?templateMotifSequenceMatchBeginPositionQ9HWC181 ; faldo:reference isoform:Q9HWC1-1 . ?templateMotifSequenceProfileAlignmentOperationQ9HWC187 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . ?targetMotifMatch88 faldo:location ?targetMotifMatchRegionMatch89 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0127491 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9HWC1MF_0127482 . ?targetMotifMatchRegionMatch89 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0127490 . ?targetMotifMatchRegionMatchBeginMF_0127490 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0127483 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0127491 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_0127480, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_0127480) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_0127480, CONCAT('^(?:-*[^-]){', STR(((6 - ?templateMotifSequenceMatchBeginPositionQ9HWC181) + 1)), '}'), '')))), '[a-z]', '')) AS ?step192) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127482, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127482) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127482, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step192), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127482, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127482) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127482, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step192), '}'), '')))), '[^-]', ''))) AS ?step293) . BIND(((?step293 + ?targetMotifMatchRegionMatchBeginPositionMF_0127483) - 1) AS ?thisPositionOn26) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_0127480, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_0127480) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_0127480, CONCAT('^(?:-*[^-]){', STR(((13 - ?templateMotifSequenceMatchBeginPositionQ9HWC181) + 1)), '}'), '')))), '[a-z]', '')) AS ?step194) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127482, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127482) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127482, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step194), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127482, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127482) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127482, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step194), '}'), '')))), '[^-]', ''))) AS ?step295) . BIND(((?step295 + ?targetMotifMatchRegionMatchBeginPositionMF_0127483) - 1) AS ?thisPositionOn27) . BIND(?this AS ?pfs2t96) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn26))) AS ?pfsb23) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn27))) AS ?pfse24) . FILTER ((BOUND(?thisPositionOn26) && BOUND(?thisPositionOn27))) . BIND(URI(CONCAT(STR(?this), '#MF_01274a22')) AS ?annotation22) . BIND(?this AS ?pfs21) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch101 faldo:location ?templateMotifSequenceMatchRegionQ9HWC1102 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9HWC1104 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9HWC1MF_0127497 . ?templateMotifSequenceMatchRegionQ9HWC1102 faldo:begin ?templateMotifSequenceMatchBeginQ9HWC1103 . ?templateMotifSequenceMatchBeginQ9HWC1103 faldo:position ?templateMotifSequenceMatchBeginPositionQ9HWC198 ; faldo:reference isoform:Q9HWC1-1 . ?templateMotifSequenceProfileAlignmentOperationQ9HWC1104 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . ?targetMotifMatch105 faldo:location ?targetMotifMatchRegionMatch106 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01274108 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9HWC1MF_0127499 . ?targetMotifMatchRegionMatch106 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01274107 . ?targetMotifMatchRegionMatchBeginMF_01274107 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01274100 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01274108 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_0127497, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_0127497) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_0127497, CONCAT('^(?:-*[^-]){', STR(((99 - ?templateMotifSequenceMatchBeginPositionQ9HWC198) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1109) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127499, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127499) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127499, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1109), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127499, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127499) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127499, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1109), '}'), '')))), '[^-]', ''))) AS ?step2110) . BIND(((?step2110 + ?targetMotifMatchRegionMatchBeginPositionMF_01274100) - 1) AS ?thisPositionOn34) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_0127497, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_0127497) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_0127497, CONCAT('^(?:-*[^-]){', STR(((102 - ?templateMotifSequenceMatchBeginPositionQ9HWC198) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1111) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127499, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127499) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127499, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1111), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_0127499, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_0127499) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_0127499, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1111), '}'), '')))), '[^-]', ''))) AS ?step2112) . BIND(((?step2112 + ?targetMotifMatchRegionMatchBeginPositionMF_01274100) - 1) AS ?thisPositionOn35) . BIND(?this AS ?pfs2t113) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn34))) AS ?pfsb30) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn35))) AS ?pfse31) . FILTER (REGEX('G[ARNDCQEGHILKMFPSTWYVBZJUOX]D[ARNDCQEGHILKMFPSTWYVBZJUOX]', SUBSTR(?thisSequenceValue, ?thisPositionOn34, (?thisPositionOn35 - ?thisPositionOn34)))) . BIND(URI(CONCAT(STR(?this), '#MF_01274a29')) AS ?annotation29) . BIND(?this AS ?pfs28) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch118 faldo:location ?templateMotifSequenceMatchRegionQ9HWC1119 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9HWC1121 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9HWC1MF_01274114 . ?templateMotifSequenceMatchRegionQ9HWC1119 faldo:begin ?templateMotifSequenceMatchBeginQ9HWC1120 . ?templateMotifSequenceMatchBeginQ9HWC1120 faldo:position ?templateMotifSequenceMatchBeginPositionQ9HWC1115 ; faldo:reference isoform:Q9HWC1-1 . ?templateMotifSequenceProfileAlignmentOperationQ9HWC1121 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . ?targetMotifMatch122 faldo:location ?targetMotifMatchRegionMatch123 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01274125 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9HWC1MF_01274116 . ?targetMotifMatchRegionMatch123 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01274124 . ?targetMotifMatchRegionMatchBeginMF_01274124 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01274117 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01274125 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_01274114, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_01274114) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_01274114, CONCAT('^(?:-*[^-]){', STR(((101 - ?templateMotifSequenceMatchBeginPositionQ9HWC1115) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1126) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_01274116, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_01274116) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_01274116, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1126), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_01274116, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_01274116) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_01274116, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1126), '}'), '')))), '[^-]', ''))) AS ?step2127) . BIND(((?step2127 + ?targetMotifMatchRegionMatchBeginPositionMF_01274117) - 1) AS ?thisPositionOn40) . BIND(?thisPositionOn40 AS ?thisPositionOn41) . BIND(?this AS ?pfs2t128) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn40))) AS ?pfsb38) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn41))) AS ?pfse39) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn40, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_01274a37')) AS ?annotation37) . BIND(?this AS ?pfs36) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch133 faldo:location ?templateMotifSequenceMatchRegionQ9HWC1134 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9HWC1136 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9HWC1MF_01274129 . ?templateMotifSequenceMatchRegionQ9HWC1134 faldo:begin ?templateMotifSequenceMatchBeginQ9HWC1135 . ?templateMotifSequenceMatchBeginQ9HWC1135 faldo:position ?templateMotifSequenceMatchBeginPositionQ9HWC1130 ; faldo:reference isoform:Q9HWC1-1 . ?templateMotifSequenceProfileAlignmentOperationQ9HWC1136 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . ?targetMotifMatch137 faldo:location ?targetMotifMatchRegionMatch138 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01274140 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9HWC1MF_01274131 . ?targetMotifMatchRegionMatch138 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01274139 . ?targetMotifMatchRegionMatchBeginMF_01274139 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01274132 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01274140 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_01274129, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_01274129) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_01274129, CONCAT('^(?:-*[^-]){', STR(((92 - ?templateMotifSequenceMatchBeginPositionQ9HWC1130) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1141) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_01274131, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_01274131) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_01274131, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1141), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_01274131, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_01274131) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_01274131, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1141), '}'), '')))), '[^-]', ''))) AS ?step2142) . BIND(((?step2142 + ?targetMotifMatchRegionMatchBeginPositionMF_01274132) - 1) AS ?thisPositionOn48) . BIND(?thisPositionOn48 AS ?thisPositionOn49) . BIND(?this AS ?pfs2t143) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn48))) AS ?pfsb44) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn49))) AS ?pfse45) . FILTER (REGEX('[YF]', SUBSTR(?thisSequenceValue, ?thisPositionOn48, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01274a43')) AS ?annotation43) . BIND(?this AS ?pfs42) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch148 faldo:location ?templateMotifSequenceMatchRegionQ9HWC1149 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9HWC1151 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9HWC1MF_01274144 . ?templateMotifSequenceMatchRegionQ9HWC1149 faldo:begin ?templateMotifSequenceMatchBeginQ9HWC1150 . ?templateMotifSequenceMatchBeginQ9HWC1150 faldo:position ?templateMotifSequenceMatchBeginPositionQ9HWC1145 ; faldo:reference isoform:Q9HWC1-1 . ?templateMotifSequenceProfileAlignmentOperationQ9HWC1151 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . ?targetMotifMatch152 faldo:location ?targetMotifMatchRegionMatch153 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01274155 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9HWC1MF_01274146 . ?targetMotifMatchRegionMatch153 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01274154 . ?targetMotifMatchRegionMatchBeginMF_01274154 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01274147 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01274155 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_01274144, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_01274144) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_01274144, CONCAT('^(?:-*[^-]){', STR(((124 - ?templateMotifSequenceMatchBeginPositionQ9HWC1145) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1156) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_01274146, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_01274146) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_01274146, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1156), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_01274146, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_01274146) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_01274146, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1156), '}'), '')))), '[^-]', ''))) AS ?step2157) . BIND(((?step2157 + ?targetMotifMatchRegionMatchBeginPositionMF_01274147) - 1) AS ?thisPositionOn55) . BIND(?thisPositionOn55 AS ?thisPositionOn56) . BIND(?this AS ?pfs2t158) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn55))) AS ?pfsb52) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn56))) AS ?pfse53) . FILTER (REGEX('[TS]', SUBSTR(?thisSequenceValue, ?thisPositionOn55, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01274a51')) AS ?annotation51) . BIND(?this AS ?pfs50) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch163 faldo:location ?templateMotifSequenceMatchRegionQ9HWC1164 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9HWC1166 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9HWC1MF_01274159 . ?templateMotifSequenceMatchRegionQ9HWC1164 faldo:begin ?templateMotifSequenceMatchBeginQ9HWC1165 . ?templateMotifSequenceMatchBeginQ9HWC1165 faldo:position ?templateMotifSequenceMatchBeginPositionQ9HWC1160 ; faldo:reference isoform:Q9HWC1-1 . ?templateMotifSequenceProfileAlignmentOperationQ9HWC1166 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . ?targetMotifMatch167 faldo:location ?targetMotifMatchRegionMatch168 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01274170 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9HWC1MF_01274161 . ?targetMotifMatchRegionMatch168 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01274169 . ?targetMotifMatchRegionMatchBeginMF_01274169 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01274162 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01274170 edam:has_input signature:MF_01274 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9HWC1MF_01274159, 1, (STRLEN(?templateMotifCigarQ9HWC1MF_01274159) - STRLEN(REPLACE(?templateMotifCigarQ9HWC1MF_01274159, CONCAT('^(?:-*[^-]){', STR(((180 - ?templateMotifSequenceMatchBeginPositionQ9HWC1160) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1171) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_01274161, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_01274161) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_01274161, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1171), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9HWC1MF_01274161, 1, (STRLEN(?targetMotifMatchCigarQ9HWC1MF_01274161) - STRLEN(REPLACE(?targetMotifMatchCigarQ9HWC1MF_01274161, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1171), '}'), '')))), '[^-]', ''))) AS ?step2172) . BIND(((?step2172 + ?targetMotifMatchRegionMatchBeginPositionMF_01274162) - 1) AS ?thisPositionOn63) . BIND(?thisPositionOn63 AS ?thisPositionOn64) . BIND(?this AS ?pfs2t173) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn63))) AS ?pfsb59) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn64))) AS ?pfse60) . FILTER (REGEX('[TS]', SUBSTR(?thisSequenceValue, ?thisPositionOn63, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01274a58')) AS ?annotation58) . BIND(?this AS ?pfs57) . } OPTIONAL { ?this a up:Protein . BIND(?this AS ?caseWithTag174) . } BIND(IF(BOUND(?tagFT_4), ?caseWithTag174, ?UNBOUND_VARIABLE) AS ?case13) . }