CONSTRUCT { _:509422 up:source unirule:MF_01408 . _:509423 up:source unirule:MF_01408 . _:509424 up:source unirule:MF_01408 . _:509425 up:source unirule:MF_01408 . _:509426 up:source unirule:MF_01408 . _:509427 up:source unirule:MF_01408 . _:509428 up:source unirule:MF_01408 . _:509429 up:source unirule:MF_01408 . _:509430 up:source unirule:MF_01408 . _:509431 up:source unirule:MF_01408 . _:509432 up:source unirule:MF_01408 . _:509433 up:source unirule:MF_01408 . _:509434 up:source unirule:MF_01408 . _:509435 up:source unirule:MF_01408 . _:509436 up:source unirule:MF_01408 . _:509437 up:source unirule:MF_01408 . _:509438 up:source unirule:MF_01408 . _:509439 up:source unirule:MF_01408 . _:509440 up:source unirule:MF_01408 . _:509441 up:source unirule:MF_01408 . _:509442 up:source unirule:MF_01408 . _:509443 up:source unirule:MF_01408 . _:509444 up:source unirule:MF_01408 . _:509445 up:source unirule:MF_01408 . _:509446 up:source unirule:MF_01408 . _:509447 up:source unirule:MF_01408 . _:509448 up:source unirule:MF_01408 . _:509449 up:source unirule:MF_01408 . _:509450 up:source unirule:MF_01408 . _:509451 up:source unirule:MF_01408 . ?this up:alternativeName ?name1 , ?name2 ; up:annotation ?annotation4 , ?annotation5 , ?annotation7 , ?annotation8 , ?annotation9 , ?annotation10 ; up:classifiedWith GO:0006231 , GO:0006235 , GO:0050797 , keyword:274 , keyword:285 , keyword:489 , keyword:521 , keyword:545 , keyword:808 ; up:recommendedName ?name0 . ?name0 up:ecName '2.1.1.148' ; up:fullName 'Flavin-dependent thymidylate synthase' ; up:shortName 'FDTS' ; rdf:type up:Structured_Name . ?name1 up:fullName 'FAD-dependent thymidylate synthase' ; rdf:type up:Structured_Name . ?name2 up:fullName 'Thymidylate synthase ThyX' ; up:shortName 'TS' , 'TSase' ; rdf:type up:Structured_Name . ?gene3 skos:prefLabel 'thyX' . ?annotation4 a up:Function_Annotation ; rdfs:comment "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant." . ?annotation5 up:activity ?activity6 ; rdf:type up:Catalytic_Activity_Annotation . ?activity6 up:catalyticActivity <http://rdf.rhea-db.org/29043>; up:enzymeClass <http://purl.uniprot.org/enzyme/2.1.1.148>. ?annotation7 up:cofactor chebi:57692 ; rdf:type up:Cofactor_Annotation ; rdfs:comment 'Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.' . ?annotation8 a up:Pathway_Annotation ; rdfs:comment 'Pyrimidine metabolism; dTTP biosynthesis.' . ?annotation9 a up:Subunit_Annotation ; rdfs:comment 'Homotetramer.' . ?annotation10 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the thymidylate synthase ThyX family.' . ?pfs11 up:annotation ?annotation12 . ?annotation12 faldo:begin ?pfsb13 ; faldo:end ?pfse14 ; up:ligand ?ligand15 ; rdf:type up:Binding_Site_Annotation ; rdfs:comment 'in other chain' . ?pfsb13 faldo:position ?thisPositionOn16 ; rdf:type faldo:ExactPosition . ?pfse14 faldo:position ?thisPositionOn17 ; rdf:type faldo:ExactPosition . ?ligand15 rdfs:subClassOf chebi:246422 . ?pfs18 up:annotation ?annotation19 . ?annotation19 faldo:begin ?pfsb20 ; faldo:end ?pfse21 ; up:ligand ?ligand22 ; rdf:type up:Binding_Site_Annotation . ?pfsb20 faldo:position ?thisPositionOn23 ; rdf:type faldo:ExactPosition . ?pfse21 faldo:position ?thisPositionOn24 ; rdf:type faldo:ExactPosition . ?ligand22 rdfs:subClassOf chebi:57692 . ?pfs25 up:annotation ?annotation26 . ?annotation26 faldo:begin ?pfsb27 ; faldo:end ?pfse28 ; up:ligand ?ligand29 ; rdf:type up:Binding_Site_Annotation . ?pfsb27 faldo:position ?thisPositionOn30 ; rdf:type faldo:ExactPosition . ?pfse28 faldo:position ?thisPositionOn31 ; rdf:type faldo:ExactPosition . ?ligand29 rdfs:subClassOf chebi:57692 . ?pfs32 up:annotation ?annotation33 . ?annotation33 faldo:begin ?pfsb34 ; faldo:end ?pfse35 ; up:ligand ?ligand36 ; rdf:type up:Binding_Site_Annotation . ?pfsb34 faldo:position ?thisPositionOn37 ; rdf:type faldo:ExactPosition . ?pfse35 faldo:position ?thisPositionOn38 ; rdf:type faldo:ExactPosition . ?ligand36 rdfs:subClassOf chebi:246422 . ?pfs39 up:annotation ?annotation40 . ?annotation40 faldo:begin ?pfsb41 ; faldo:end ?pfse42 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Involved in ionization of N3 of dUMP, leading to its activation' . ?pfsb41 faldo:position ?thisPositionOn43 ; rdf:type faldo:ExactPosition . ?pfse42 faldo:position ?thisPositionOn44 ; rdf:type faldo:ExactPosition . ?pfs45 up:annotation ?annotation46 . ?annotation46 faldo:begin ?pfsb47 ; faldo:end ?pfse48 ; up:ligand ?ligand49 ; rdf:type up:Binding_Site_Annotation . ?pfsb47 faldo:position ?thisPositionOn50 ; rdf:type faldo:ExactPosition . ?pfse48 faldo:position ?thisPositionOn51 ; rdf:type faldo:ExactPosition . ?ligand49 rdfs:subClassOf chebi:57692 . ?pfs52 up:annotation ?annotation53 . ?annotation53 faldo:begin ?pfsb54 ; faldo:end ?pfse55 ; up:ligand ?ligand56 ; rdf:type up:Binding_Site_Annotation . ?pfsb54 faldo:position ?thisPositionOn57 ; rdf:type faldo:ExactPosition . ?pfse55 faldo:position ?thisPositionOn58 ; rdf:type faldo:ExactPosition . ?ligand56 rdfs:subClassOf chebi:57692 . ?pfs59 up:annotation ?annotation60 . ?annotation60 faldo:begin ?pfsb61 ; faldo:end ?pfse62 ; up:ligand ?ligand63 ; rdf:type up:Binding_Site_Annotation . ?pfsb61 faldo:position ?thisPositionOn64 ; rdf:type faldo:ExactPosition . ?pfse62 faldo:position ?thisPositionOn65 ; rdf:type faldo:ExactPosition . ?ligand63 rdfs:subClassOf chebi:57692 . ?pfs66 up:annotation ?annotation67 . ?annotation67 faldo:begin ?pfsb68 ; faldo:end ?pfse69 ; up:ligand ?ligand70 ; rdf:type up:Binding_Site_Annotation ; rdfs:comment 'in other chain' . ?pfsb68 faldo:position ?thisPositionOn71 ; rdf:type faldo:ExactPosition . ?pfse69 faldo:position ?thisPositionOn72 ; rdf:type faldo:ExactPosition . ?ligand70 rdfs:subClassOf chebi:246422 . ?pfs73 up:annotation ?annotation74 . ?annotation74 faldo:begin ?pfsb75 ; faldo:end ?pfse76 ; up:ligand ?ligand77 ; rdf:type up:Binding_Site_Annotation . ?pfsb75 faldo:position ?thisPositionOn78 ; rdf:type faldo:ExactPosition . ?pfse76 faldo:position ?thisPositionOn79 ; rdf:type faldo:ExactPosition . ?ligand77 rdfs:subClassOf chebi:246422 . ?pfs80 up:annotation ?annotation81 . ?annotation81 faldo:begin ?pfsb82 ; faldo:end ?pfse83 ; up:ligand ?ligand84 ; rdf:type up:Binding_Site_Annotation ; rdfs:comment 'in other chain' . ?pfsb82 faldo:position ?thisPositionOn85 ; rdf:type faldo:ExactPosition . ?pfse83 faldo:position ?thisPositionOn86 ; rdf:type faldo:ExactPosition . ?ligand84 rdfs:subClassOf chebi:246422 . _:509452 a rdf:Statement ; up:attribution _:509422 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:509453 a rdf:Statement ; up:attribution _:509423 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name1 . _:509454 a rdf:Statement ; up:attribution _:509424 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name2 . _:509455 a rdf:Statement ; up:attribution _:509425 ; rdf:subject ?gene3 ; rdf:predicate up:encodedBy ; rdf:object ?gene3 . _:509456 a rdf:Statement ; up:attribution _:509426 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation4 . _:509457 a rdf:Statement ; up:attribution _:509427 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation5 . _:509458 a rdf:Statement ; up:attribution _:509428 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation7 . _:509459 a rdf:Statement ; up:attribution _:509429 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation8 . _:509460 a rdf:Statement ; up:attribution _:509430 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation9 . _:509461 a rdf:Statement ; up:attribution _:509431 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation10 . _:509462 a rdf:Statement ; up:attribution _:509432 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:808 . _:509463 a rdf:Statement ; up:attribution _:509433 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:489 . _:509464 a rdf:Statement ; up:attribution _:509434 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:545 . _:509465 a rdf:Statement ; up:attribution _:509435 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:274 . _:509466 a rdf:Statement ; up:attribution _:509436 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:285 . _:509467 a rdf:Statement ; up:attribution _:509437 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:521 . _:509468 a rdf:Statement ; up:attribution _:509438 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0050797 . _:509469 a rdf:Statement ; up:attribution _:509439 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0006231 . _:509470 a rdf:Statement ; up:attribution _:509440 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0006235 . _:509471 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:509472 a rdf:Statement ; up:attribution _:509441 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:509473 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs18 ; rdf:predicate up:annotation ; rdf:object ?annotation19 . _:509474 a rdf:Statement ; up:attribution _:509442 ; rdf:subject ?pfs18 ; rdf:predicate up:annotation ; rdf:object ?annotation19 . _:509475 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs25 ; rdf:predicate up:annotation ; rdf:object ?annotation26 . _:509476 a rdf:Statement ; up:attribution _:509443 ; rdf:subject ?pfs25 ; rdf:predicate up:annotation ; rdf:object ?annotation26 . _:509477 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs32 ; rdf:predicate up:annotation ; rdf:object ?annotation33 . _:509478 a rdf:Statement ; up:attribution _:509444 ; rdf:subject ?pfs32 ; rdf:predicate up:annotation ; rdf:object ?annotation33 . _:509479 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs39 ; rdf:predicate up:annotation ; rdf:object ?annotation40 . _:509480 a rdf:Statement ; up:attribution _:509445 ; rdf:subject ?pfs39 ; rdf:predicate up:annotation ; rdf:object ?annotation40 . _:509481 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs45 ; rdf:predicate up:annotation ; rdf:object ?annotation46 . _:509482 a rdf:Statement ; up:attribution _:509446 ; rdf:subject ?pfs45 ; rdf:predicate up:annotation ; rdf:object ?annotation46 . _:509483 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs52 ; rdf:predicate up:annotation ; rdf:object ?annotation53 . _:509484 a rdf:Statement ; up:attribution _:509447 ; rdf:subject ?pfs52 ; rdf:predicate up:annotation ; rdf:object ?annotation53 . _:509485 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs59 ; rdf:predicate up:annotation ; rdf:object ?annotation60 . _:509486 a rdf:Statement ; up:attribution _:509448 ; rdf:subject ?pfs59 ; rdf:predicate up:annotation ; rdf:object ?annotation60 . _:509487 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs66 ; rdf:predicate up:annotation ; rdf:object ?annotation67 . _:509488 a rdf:Statement ; up:attribution _:509449 ; rdf:subject ?pfs66 ; rdf:predicate up:annotation ; rdf:object ?annotation67 . _:509489 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs73 ; rdf:predicate up:annotation ; rdf:object ?annotation74 . _:509490 a rdf:Statement ; up:attribution _:509450 ; rdf:subject ?pfs73 ; rdf:predicate up:annotation ; rdf:object ?annotation74 . _:509491 a rdf:Statement ; up:source unirule:MF_01408 ; rdf:subject ?pfs80 ; rdf:predicate up:annotation ; rdf:object ?annotation81 . _:509492 a rdf:Statement ; up:attribution _:509451 ; rdf:subject ?pfs80 ; rdf:predicate up:annotation ; rdf:object ?annotation81 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_01408 #Rule MF_01408 Created by:? on:2005-02-28 Modified by:Edouard de Castro on:2024-09-02 VALUES ?supertaxon87 {taxon:2 taxon:2157} ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_01408 . ?thisOrganism rdfs:subClassOf+ ?supertaxon87 . BIND(URI(CONCAT(STR(?this), '#MF_01408a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_01408a1')) AS ?name1) . BIND(URI(CONCAT(STR(?this), '#MF_01408a2')) AS ?name2) . BIND(URI(CONCAT(STR(?this), '#MF_01408a4')) AS ?annotation4) . BIND(URI(CONCAT(STR(?this), '#MF_01408a5')) AS ?annotation5) . BIND(URI(CONCAT(STR(?this), '#MF_01408a7')) AS ?annotation7) . BIND(URI(CONCAT(STR(?this), '#MF_01408a8')) AS ?annotation8) . BIND(URI(CONCAT(STR(?this), '#MF_01408a9')) AS ?annotation9) . BIND(URI(CONCAT(STR(?this), '#MF_01408a10')) AS ?annotation10) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch92 faldo:location ?templateMotifSequenceMatchRegionQ9WYT093 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT095 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_0140888 . ?templateMotifSequenceMatchRegionQ9WYT093 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT094 . ?templateMotifSequenceMatchBeginQ9WYT094 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT089 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT095 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch96 faldo:location ?targetMotifMatchRegionMatch97 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0140899 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_0140890 . ?targetMotifMatchRegionMatch97 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0140898 . ?targetMotifMatchRegionMatchBeginMF_0140898 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0140891 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0140899 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(?this AS ?tagFT_4) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_0140888, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_0140888) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_0140888, CONCAT('^(?:-*[^-]){', STR(((86 - ?templateMotifSequenceMatchBeginPositionQ9WYT089) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1100) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_0140890, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_0140890) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_0140890, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1100), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_0140890, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_0140890) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_0140890, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1100), '}'), '')))), '[^-]', ''))) AS ?step2101) . BIND(((?step2101 + ?targetMotifMatchRegionMatchBeginPositionMF_0140891) - 1) AS ?thisPositionOn16) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_0140888, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_0140888) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_0140888, CONCAT('^(?:-*[^-]){', STR(((90 - ?templateMotifSequenceMatchBeginPositionQ9WYT089) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1102) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_0140890, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_0140890) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_0140890, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1102), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_0140890, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_0140890) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_0140890, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1102), '}'), '')))), '[^-]', ''))) AS ?step2103) . BIND(((?step2103 + ?targetMotifMatchRegionMatchBeginPositionMF_0140891) - 1) AS ?thisPositionOn17) . BIND(?this AS ?pfs1t104) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn16))) AS ?pfsb13) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn17))) AS ?pfse14) . FILTER (REGEX('[EQ][ARNDCQEGHILKMFPSTWYVBZJUOX]S[ARNDCQEGHILKMFPSTWYVBZJUOX]R', SUBSTR(?thisSequenceValue, ?thisPositionOn16, (?thisPositionOn17 - ?thisPositionOn16)))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a12')) AS ?annotation12) . BIND(?this AS ?pfs11) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch109 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0110 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0112 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408105 . ?templateMotifSequenceMatchRegionQ9WYT0110 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0111 . ?templateMotifSequenceMatchBeginQ9WYT0111 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0106 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0112 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch113 faldo:location ?targetMotifMatchRegionMatch114 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408116 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408107 . ?targetMotifMatchRegionMatch114 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408115 . ?targetMotifMatchRegionMatchBeginMF_01408115 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408108 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408116 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408105, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408105) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408105, CONCAT('^(?:-*[^-]){', STR(((78 - ?templateMotifSequenceMatchBeginPositionQ9WYT0106) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1117) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408107, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408107) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408107, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1117), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408107, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408107) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408107, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1117), '}'), '')))), '[^-]', ''))) AS ?step2118) . BIND(((?step2118 + ?targetMotifMatchRegionMatchBeginPositionMF_01408108) - 1) AS ?thisPositionOn23) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408105, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408105) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408105, CONCAT('^(?:-*[^-]){', STR(((80 - ?templateMotifSequenceMatchBeginPositionQ9WYT0106) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1119) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408107, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408107) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408107, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1119), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408107, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408107) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408107, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1119), '}'), '')))), '[^-]', ''))) AS ?step2120) . BIND(((?step2120 + ?targetMotifMatchRegionMatchBeginPositionMF_01408108) - 1) AS ?thisPositionOn24) . BIND(?this AS ?pfs2t121) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn23))) AS ?pfsb20) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn24))) AS ?pfse21) . FILTER (REGEX('R[ARNDCQEGHILKMFPSTWYVBZJUOX]R', SUBSTR(?thisSequenceValue, ?thisPositionOn23, (?thisPositionOn24 - ?thisPositionOn23)))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a19')) AS ?annotation19) . BIND(?this AS ?pfs18) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch126 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0127 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0129 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408122 . ?templateMotifSequenceMatchRegionQ9WYT0127 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0128 . ?templateMotifSequenceMatchBeginQ9WYT0128 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0123 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0129 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch130 faldo:location ?targetMotifMatchRegionMatch131 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408133 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408124 . ?targetMotifMatchRegionMatch131 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408132 . ?targetMotifMatchRegionMatchBeginMF_01408132 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408125 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408133 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408122, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408122) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408122, CONCAT('^(?:-*[^-]){', STR(((163 - ?templateMotifSequenceMatchBeginPositionQ9WYT0123) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1134) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408124, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408124) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408124, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1134), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408124, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408124) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408124, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1134), '}'), '')))), '[^-]', ''))) AS ?step2135) . BIND(((?step2135 + ?targetMotifMatchRegionMatchBeginPositionMF_01408125) - 1) AS ?thisPositionOn30) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408122, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408122) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408122, CONCAT('^(?:-*[^-]){', STR(((165 - ?templateMotifSequenceMatchBeginPositionQ9WYT0123) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1136) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408124, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408124) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408124, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1136), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408124, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408124) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408124, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1136), '}'), '')))), '[^-]', ''))) AS ?step2137) . BIND(((?step2137 + ?targetMotifMatchRegionMatchBeginPositionMF_01408125) - 1) AS ?thisPositionOn31) . BIND(?this AS ?pfs2t138) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn30))) AS ?pfsb27) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn31))) AS ?pfse28) . FILTER (REGEX('[ND][ARNDCQEGHILKMFPSTWYVBZJUOX][RHN]', SUBSTR(?thisSequenceValue, ?thisPositionOn30, (?thisPositionOn31 - ?thisPositionOn30)))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a26')) AS ?annotation26) . BIND(?this AS ?pfs25) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch143 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0144 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0146 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408139 . ?templateMotifSequenceMatchRegionQ9WYT0144 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0145 . ?templateMotifSequenceMatchBeginQ9WYT0145 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0140 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0146 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch147 faldo:location ?targetMotifMatchRegionMatch148 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408150 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408141 . ?targetMotifMatchRegionMatch148 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408149 . ?targetMotifMatchRegionMatchBeginMF_01408149 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408142 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408150 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408139, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408139) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408139, CONCAT('^(?:-*[^-]){', STR(((75 - ?templateMotifSequenceMatchBeginPositionQ9WYT0140) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1151) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408141, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408141) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408141, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1151), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408141, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408141) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408141, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1151), '}'), '')))), '[^-]', ''))) AS ?step2152) . BIND(((?step2152 + ?targetMotifMatchRegionMatchBeginPositionMF_01408142) - 1) AS ?thisPositionOn37) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408139, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408139) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408139, CONCAT('^(?:-*[^-]){', STR(((78 - ?templateMotifSequenceMatchBeginPositionQ9WYT0140) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1153) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408141, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408141) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408141, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1153), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408141, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408141) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408141, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1153), '}'), '')))), '[^-]', ''))) AS ?step2154) . BIND(((?step2154 + ?targetMotifMatchRegionMatchBeginPositionMF_01408142) - 1) AS ?thisPositionOn38) . BIND(?this AS ?pfs2t155) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn37))) AS ?pfsb34) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn38))) AS ?pfse35) . FILTER (REGEX('[QE][ARNDCQEGHILKMFPSTWYVBZJUOX][ARNDCQEGHILKMFPSTWYVBZJUOX]R', SUBSTR(?thisSequenceValue, ?thisPositionOn37, (?thisPositionOn38 - ?thisPositionOn37)))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a33')) AS ?annotation33) . BIND(?this AS ?pfs32) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch160 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0161 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0163 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408156 . ?templateMotifSequenceMatchRegionQ9WYT0161 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0162 . ?templateMotifSequenceMatchBeginQ9WYT0162 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0157 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0163 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch164 faldo:location ?targetMotifMatchRegionMatch165 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408167 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408158 . ?targetMotifMatchRegionMatch165 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408166 . ?targetMotifMatchRegionMatchBeginMF_01408166 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408159 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408167 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408156, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408156) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408156, CONCAT('^(?:-*[^-]){', STR(((174 - ?templateMotifSequenceMatchBeginPositionQ9WYT0157) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1168) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408158, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408158) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408158, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1168), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408158, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408158) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408158, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1168), '}'), '')))), '[^-]', ''))) AS ?step2169) . BIND(((?step2169 + ?targetMotifMatchRegionMatchBeginPositionMF_01408159) - 1) AS ?thisPositionOn43) . BIND(?thisPositionOn43 AS ?thisPositionOn44) . BIND(?this AS ?pfs2t170) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn43))) AS ?pfsb41) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn44))) AS ?pfse42) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn43, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_01408a40')) AS ?annotation40) . BIND(?this AS ?pfs39) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch175 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0176 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0178 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408171 . ?templateMotifSequenceMatchRegionQ9WYT0176 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0177 . ?templateMotifSequenceMatchBeginQ9WYT0177 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0172 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0178 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch179 faldo:location ?targetMotifMatchRegionMatch180 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408182 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408173 . ?targetMotifMatchRegionMatch180 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408181 . ?targetMotifMatchRegionMatchBeginMF_01408181 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408174 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408182 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408171, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408171) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408171, CONCAT('^(?:-*[^-]){', STR(((55 - ?templateMotifSequenceMatchBeginPositionQ9WYT0172) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1183) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408173, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408173) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408173, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1183), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408173, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408173) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408173, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1183), '}'), '')))), '[^-]', ''))) AS ?step2184) . BIND(((?step2184 + ?targetMotifMatchRegionMatchBeginPositionMF_01408174) - 1) AS ?thisPositionOn50) . BIND(?thisPositionOn50 AS ?thisPositionOn51) . BIND(?this AS ?pfs2t185) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn50))) AS ?pfsb47) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn51))) AS ?pfse48) . FILTER (REGEX('[TS]', SUBSTR(?thisSequenceValue, ?thisPositionOn50, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a46')) AS ?annotation46) . BIND(?this AS ?pfs45) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch190 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0191 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0193 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408186 . ?templateMotifSequenceMatchRegionQ9WYT0191 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0192 . ?templateMotifSequenceMatchBeginQ9WYT0192 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0187 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0193 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch194 faldo:location ?targetMotifMatchRegionMatch195 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408197 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408188 . ?targetMotifMatchRegionMatch195 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408196 . ?targetMotifMatchRegionMatchBeginMF_01408196 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408189 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408197 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408186, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408186) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408186, CONCAT('^(?:-*[^-]){', STR(((86 - ?templateMotifSequenceMatchBeginPositionQ9WYT0187) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1198) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408188, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408188) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408188, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1198), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408188, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408188) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408188, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1198), '}'), '')))), '[^-]', ''))) AS ?step2199) . BIND(((?step2199 + ?targetMotifMatchRegionMatchBeginPositionMF_01408189) - 1) AS ?thisPositionOn57) . BIND(?thisPositionOn57 AS ?thisPositionOn58) . BIND(?this AS ?pfs2t200) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn57))) AS ?pfsb54) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn58))) AS ?pfse55) . FILTER (REGEX('[EQ]', SUBSTR(?thisSequenceValue, ?thisPositionOn57, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a53')) AS ?annotation53) . BIND(?this AS ?pfs52) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch205 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0206 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0208 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408201 . ?templateMotifSequenceMatchRegionQ9WYT0206 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0207 . ?templateMotifSequenceMatchBeginQ9WYT0207 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0202 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0208 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch209 faldo:location ?targetMotifMatchRegionMatch210 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408212 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408203 . ?targetMotifMatchRegionMatch210 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408211 . ?targetMotifMatchRegionMatchBeginMF_01408211 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408204 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408212 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408201, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408201) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408201, CONCAT('^(?:-*[^-]){', STR(((169 - ?templateMotifSequenceMatchBeginPositionQ9WYT0202) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1213) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408203, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408203) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408203, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1213), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408203, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408203) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408203, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1213), '}'), '')))), '[^-]', ''))) AS ?step2214) . BIND(((?step2214 + ?targetMotifMatchRegionMatchBeginPositionMF_01408204) - 1) AS ?thisPositionOn64) . BIND(?thisPositionOn64 AS ?thisPositionOn65) . BIND(?this AS ?pfs2t215) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn64))) AS ?pfsb61) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn65))) AS ?pfse62) . FILTER (REGEX('[NH]', SUBSTR(?thisSequenceValue, ?thisPositionOn64, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a60')) AS ?annotation60) . BIND(?this AS ?pfs59) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch220 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0221 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0223 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408216 . ?templateMotifSequenceMatchRegionQ9WYT0221 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0222 . ?templateMotifSequenceMatchBeginQ9WYT0222 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0217 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0223 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch224 faldo:location ?targetMotifMatchRegionMatch225 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408227 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408218 . ?targetMotifMatchRegionMatch225 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408226 . ?targetMotifMatchRegionMatchBeginMF_01408226 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408219 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408227 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408216, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408216) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408216, CONCAT('^(?:-*[^-]){', STR(((147 - ?templateMotifSequenceMatchBeginPositionQ9WYT0217) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1228) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408218, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408218) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408218, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1228), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408218, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408218) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408218, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1228), '}'), '')))), '[^-]', ''))) AS ?step2229) . BIND(((?step2229 + ?targetMotifMatchRegionMatchBeginPositionMF_01408219) - 1) AS ?thisPositionOn71) . BIND(?thisPositionOn71 AS ?thisPositionOn72) . BIND(?this AS ?pfs2t230) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn71))) AS ?pfsb68) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn72))) AS ?pfse69) . FILTER (REGEX('[RKH]', SUBSTR(?thisSequenceValue, ?thisPositionOn71, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a67')) AS ?annotation67) . BIND(?this AS ?pfs66) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch235 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0236 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0238 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408231 . ?templateMotifSequenceMatchRegionQ9WYT0236 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0237 . ?templateMotifSequenceMatchBeginQ9WYT0237 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0232 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0238 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch239 faldo:location ?targetMotifMatchRegionMatch240 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408242 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408233 . ?targetMotifMatchRegionMatch240 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408241 . ?targetMotifMatchRegionMatchBeginMF_01408241 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408234 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408242 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408231, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408231) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408231, CONCAT('^(?:-*[^-]){', STR(((174 - ?templateMotifSequenceMatchBeginPositionQ9WYT0232) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1243) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408233, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408233) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408233, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1243), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408233, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408233) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408233, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1243), '}'), '')))), '[^-]', ''))) AS ?step2244) . BIND(((?step2244 + ?targetMotifMatchRegionMatchBeginPositionMF_01408234) - 1) AS ?thisPositionOn78) . BIND(?thisPositionOn78 AS ?thisPositionOn79) . BIND(?this AS ?pfs2t245) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn78))) AS ?pfsb75) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn79))) AS ?pfse76) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn78, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_01408a74')) AS ?annotation74) . BIND(?this AS ?pfs73) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch250 faldo:location ?templateMotifSequenceMatchRegionQ9WYT0251 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9WYT0253 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9WYT0MF_01408246 . ?templateMotifSequenceMatchRegionQ9WYT0251 faldo:begin ?templateMotifSequenceMatchBeginQ9WYT0252 . ?templateMotifSequenceMatchBeginQ9WYT0252 faldo:position ?templateMotifSequenceMatchBeginPositionQ9WYT0247 ; faldo:reference isoform:Q9WYT0-1 . ?templateMotifSequenceProfileAlignmentOperationQ9WYT0253 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . ?targetMotifMatch254 faldo:location ?targetMotifMatchRegionMatch255 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01408257 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9WYT0MF_01408248 . ?targetMotifMatchRegionMatch255 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01408256 . ?targetMotifMatchRegionMatchBeginMF_01408256 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01408249 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01408257 edam:has_input signature:MF_01408 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408246, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408246) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408246, CONCAT('^(?:-*[^-]){', STR(((88 - ?templateMotifSequenceMatchBeginPositionQ9WYT0247) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1258) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408248, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408248) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408248, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1258), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408248, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408248) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408248, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1258), '}'), '')))), '[^-]', ''))) AS ?step2259) . BIND(((?step2259 + ?targetMotifMatchRegionMatchBeginPositionMF_01408249) - 1) AS ?thisPositionOn85) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9WYT0MF_01408246, 1, (STRLEN(?templateMotifCigarQ9WYT0MF_01408246) - STRLEN(REPLACE(?templateMotifCigarQ9WYT0MF_01408246, CONCAT('^(?:-*[^-]){', STR(((90 - ?templateMotifSequenceMatchBeginPositionQ9WYT0247) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1260) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408248, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408248) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408248, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1260), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9WYT0MF_01408248, 1, (STRLEN(?targetMotifMatchCigarQ9WYT0MF_01408248) - STRLEN(REPLACE(?targetMotifMatchCigarQ9WYT0MF_01408248, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1260), '}'), '')))), '[^-]', ''))) AS ?step2261) . BIND(((?step2261 + ?targetMotifMatchRegionMatchBeginPositionMF_01408249) - 1) AS ?thisPositionOn86) . BIND(?this AS ?pfs3t262) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn85))) AS ?pfsb82) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn86))) AS ?pfse83) . FILTER (REGEX('S[ARNDCQEGHILKMFPSTWYVBZJUOX]R', SUBSTR(?thisSequenceValue, ?thisPositionOn85, (?thisPositionOn86 - ?thisPositionOn85)))) . BIND(URI(CONCAT(STR(?this), '#MF_01408a81')) AS ?annotation81) . BIND(?this AS ?pfs80) . } }