CONSTRUCT { _:618070 up:source unirule:MF_01690 . _:618071 up:source unirule:MF_01690 . _:618072 up:source unirule:MF_01690 . _:618073 up:source unirule:MF_01690 . _:618074 up:source unirule:MF_01690 . _:618075 up:source unirule:MF_01690 . _:618076 up:source unirule:MF_01690 . _:618077 up:source unirule:MF_01690 . _:618078 up:source unirule:MF_01690 . _:618079 up:source unirule:MF_01690 . _:618080 up:source unirule:MF_01690 . _:618081 up:source unirule:MF_01690 . _:618082 up:source unirule:MF_01690 . _:618083 up:source unirule:MF_01690 . _:618084 up:source unirule:MF_01690 . _:618085 up:source unirule:MF_01690 . _:618086 up:source unirule:MF_01690 . _:618087 up:source unirule:MF_01690 . _:618088 up:source unirule:MF_01690 . _:618089 up:source unirule:MF_01690 . _:618090 up:source unirule:MF_01690 . _:618091 up:source unirule:MF_01690 . _:618092 up:source unirule:MF_01690 . _:618093 up:source unirule:MF_01690 . _:618094 up:source unirule:MF_01690 . _:618095 up:source unirule:MF_01690 . _:618096 up:source unirule:MF_01690 . _:618097 up:source unirule:MF_01690 . _:618098 up:source unirule:MF_01690 . ?this up:alternativeName ?name1 ; up:annotation ?annotation3 , ?annotation4 , ?annotation6 , ?annotation7 , ?annotation8 , ?annotation9 ; up:classifiedWith GO:0008270 , GO:0009014 , GO:0009089 , GO:0019877 , GO:0050897 , keyword:170 , keyword:220 , keyword:28 , keyword:378 , keyword:457 , keyword:479 , keyword:862 ; up:recommendedName ?name0 . ?name0 up:ecName '3.5.1.18' ; up:fullName 'Succinyl-diaminopimelate desuccinylase' ; up:shortName 'SDAP desuccinylase' ; rdf:type up:Structured_Name . ?name1 up:fullName 'N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase' ; rdf:type up:Structured_Name . ?gene2 skos:prefLabel 'dapE' . ?annotation3 a up:Function_Annotation ; rdfs:comment 'Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminopimelate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.' . ?annotation4 up:activity ?activity5 ; rdf:type up:Catalytic_Activity_Annotation . ?activity5 up:catalyticActivity <http://rdf.rhea-db.org/22608>; up:enzymeClass <http://purl.uniprot.org/enzyme/3.5.1.18>. ?annotation6 up:cofactor chebi:29105 , chebi:48828 ; rdf:type up:Cofactor_Annotation ; rdfs:comment 'Binds 2 Zn(2+) or Co(2+) ions per subunit.' . ?annotation7 a up:Pathway_Annotation ; rdfs:comment 'Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 3/3.' . ?annotation8 a up:Subunit_Annotation ; rdfs:comment 'Homodimer.' . ?annotation9 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the peptidase M20A family. DapE subfamily.' . ?pfs10 up:annotation ?annotation11 . ?annotation11 faldo:begin ?pfsb12 ; faldo:end ?pfse13 ; rdf:type up:Active_Site_Annotation . ?pfsb12 faldo:position ?thisPositionOn14 ; rdf:type faldo:ExactPosition . ?pfse13 faldo:position ?thisPositionOn15 ; rdf:type faldo:ExactPosition . ?pfs16 up:annotation ?annotation17 . ?annotation17 faldo:begin ?pfsb18 ; faldo:end ?pfse19 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Proton acceptor' . ?pfsb18 faldo:position ?thisPositionOn20 ; rdf:type faldo:ExactPosition . ?pfse19 faldo:position ?thisPositionOn21 ; rdf:type faldo:ExactPosition . ?pfs22 up:annotation ?annotation23 . ?annotation23 faldo:begin ?pfsb24 ; faldo:end ?pfse25 ; up:ligand ?ligand26 ; rdf:type up:Binding_Site_Annotation . ?pfsb24 faldo:position ?thisPositionOn27 ; rdf:type faldo:ExactPosition . ?pfse25 faldo:position ?thisPositionOn28 ; rdf:type faldo:ExactPosition . ?ligand26 rdfs:subClassOf chebi:29105 . ?pfs29 up:annotation ?annotation30 . ?annotation30 faldo:begin ?pfsb31 ; faldo:end ?pfse32 ; up:ligand ?ligand33 ; rdf:type up:Binding_Site_Annotation . ?pfsb31 faldo:position ?thisPositionOn34 ; rdf:type faldo:ExactPosition . ?pfse32 faldo:position ?thisPositionOn35 ; rdf:type faldo:ExactPosition . ?ligand33 rdfs:subClassOf chebi:29105 . ?pfs36 up:annotation ?annotation37 . ?annotation37 faldo:begin ?pfsb38 ; faldo:end ?pfse39 ; up:ligand ?ligand40 ; rdf:type up:Binding_Site_Annotation . ?pfsb38 faldo:position ?thisPositionOn41 ; rdf:type faldo:ExactPosition . ?pfse39 faldo:position ?thisPositionOn42 ; rdf:type faldo:ExactPosition . ?ligand40 rdfs:subClassOf chebi:29105 . ?pfs43 up:annotation ?annotation44 . ?annotation44 faldo:begin ?pfsb45 ; faldo:end ?pfse46 ; up:ligand ?ligand47 ; rdf:type up:Binding_Site_Annotation . ?pfsb45 faldo:position ?thisPositionOn48 ; rdf:type faldo:ExactPosition . ?pfse46 faldo:position ?thisPositionOn49 ; rdf:type faldo:ExactPosition . ?ligand47 rdfs:subClassOf chebi:29105 . ?pfs50 up:annotation ?annotation51 . ?annotation51 faldo:begin ?pfsb52 ; faldo:end ?pfse53 ; up:ligand ?ligand54 ; rdf:type up:Binding_Site_Annotation . ?pfsb52 faldo:position ?thisPositionOn55 ; rdf:type faldo:ExactPosition . ?pfse53 faldo:position ?thisPositionOn56 ; rdf:type faldo:ExactPosition . ?ligand54 rdfs:subClassOf chebi:29105 . ?pfs57 up:annotation ?annotation58 . ?annotation58 faldo:begin ?pfsb59 ; faldo:end ?pfse60 ; up:ligand ?ligand61 ; rdf:type up:Binding_Site_Annotation . ?pfsb59 faldo:position ?thisPositionOn62 ; rdf:type faldo:ExactPosition . ?pfse60 faldo:position ?thisPositionOn63 ; rdf:type faldo:ExactPosition . ?ligand61 rdfs:subClassOf chebi:29105 . _:618099 a rdf:Statement ; up:attribution _:618070 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:618100 a rdf:Statement ; up:attribution _:618071 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name1 . _:618101 a rdf:Statement ; up:attribution _:618072 ; rdf:subject ?gene2 ; rdf:predicate up:encodedBy ; rdf:object ?gene2 . _:618102 a rdf:Statement ; up:attribution _:618073 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation3 . _:618103 a rdf:Statement ; up:attribution _:618074 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation4 . _:618104 a rdf:Statement ; up:attribution _:618075 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation6 . _:618105 a rdf:Statement ; up:attribution _:618076 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation7 . _:618106 a rdf:Statement ; up:attribution _:618077 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation8 . _:618107 a rdf:Statement ; up:attribution _:618078 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation9 . _:618108 a rdf:Statement ; up:attribution _:618079 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:28 . _:618109 a rdf:Statement ; up:attribution _:618080 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:170 . _:618110 a rdf:Statement ; up:attribution _:618081 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:220 . _:618111 a rdf:Statement ; up:attribution _:618082 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:378 . _:618112 a rdf:Statement ; up:attribution _:618083 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:457 . _:618113 a rdf:Statement ; up:attribution _:618084 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:479 . _:618114 a rdf:Statement ; up:attribution _:618085 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:862 . _:618115 a rdf:Statement ; up:attribution _:618086 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0008270 . _:618116 a rdf:Statement ; up:attribution _:618087 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0009014 . _:618117 a rdf:Statement ; up:attribution _:618088 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0050897 . _:618118 a rdf:Statement ; up:attribution _:618089 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0009089 . _:618119 a rdf:Statement ; up:attribution _:618090 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0019877 . _:618120 a rdf:Statement ; up:source unirule:MF_01690 ; rdf:subject ?pfs10 ; rdf:predicate up:annotation ; rdf:object ?annotation11 . _:618121 a rdf:Statement ; up:attribution _:618091 ; rdf:subject ?pfs10 ; rdf:predicate up:annotation ; rdf:object ?annotation11 . _:618122 a rdf:Statement ; up:source unirule:MF_01690 ; rdf:subject ?pfs16 ; rdf:predicate up:annotation ; rdf:object ?annotation17 . _:618123 a rdf:Statement ; up:attribution _:618092 ; rdf:subject ?pfs16 ; rdf:predicate up:annotation ; rdf:object ?annotation17 . _:618124 a rdf:Statement ; up:source unirule:MF_01690 ; rdf:subject ?pfs22 ; rdf:predicate up:annotation ; rdf:object ?annotation23 . _:618125 a rdf:Statement ; up:attribution _:618093 ; rdf:subject ?pfs22 ; rdf:predicate up:annotation ; rdf:object ?annotation23 . _:618126 a rdf:Statement ; up:source unirule:MF_01690 ; rdf:subject ?pfs29 ; rdf:predicate up:annotation ; rdf:object ?annotation30 . _:618127 a rdf:Statement ; up:attribution _:618094 ; rdf:subject ?pfs29 ; rdf:predicate up:annotation ; rdf:object ?annotation30 . _:618128 a rdf:Statement ; up:source unirule:MF_01690 ; rdf:subject ?pfs36 ; rdf:predicate up:annotation ; rdf:object ?annotation37 . _:618129 a rdf:Statement ; up:attribution _:618095 ; rdf:subject ?pfs36 ; rdf:predicate up:annotation ; rdf:object ?annotation37 . _:618130 a rdf:Statement ; up:source unirule:MF_01690 ; rdf:subject ?pfs43 ; rdf:predicate up:annotation ; rdf:object ?annotation44 . _:618131 a rdf:Statement ; up:attribution _:618096 ; rdf:subject ?pfs43 ; rdf:predicate up:annotation ; rdf:object ?annotation44 . _:618132 a rdf:Statement ; up:source unirule:MF_01690 ; rdf:subject ?pfs50 ; rdf:predicate up:annotation ; rdf:object ?annotation51 . _:618133 a rdf:Statement ; up:attribution _:618097 ; rdf:subject ?pfs50 ; rdf:predicate up:annotation ; rdf:object ?annotation51 . _:618134 a rdf:Statement ; up:source unirule:MF_01690 ; rdf:subject ?pfs57 ; rdf:predicate up:annotation ; rdf:object ?annotation58 . _:618135 a rdf:Statement ; up:attribution _:618098 ; rdf:subject ?pfs57 ; rdf:predicate up:annotation ; rdf:object ?annotation58 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_01690 #Rule MF_01690 Created by:? on:2009-04-22 Modified by:Elisabeth Coudert on:2025-01-09 ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_01690 . ?thisOrganism rdfs:subClassOf+ taxon:1224 . BIND(URI(CONCAT(STR(?this), '#MF_01690a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_01690a1')) AS ?name1) . BIND(URI(CONCAT(STR(?this), '#MF_01690a3')) AS ?annotation3) . BIND(URI(CONCAT(STR(?this), '#MF_01690a4')) AS ?annotation4) . BIND(URI(CONCAT(STR(?this), '#MF_01690a6')) AS ?annotation6) . BIND(URI(CONCAT(STR(?this), '#MF_01690a7')) AS ?annotation7) . BIND(URI(CONCAT(STR(?this), '#MF_01690a8')) AS ?annotation8) . BIND(URI(CONCAT(STR(?this), '#MF_01690a9')) AS ?annotation9) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch68 faldo:location ?templateMotifSequenceMatchRegionP4451469 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP4451471 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP44514MF_0169064 . ?templateMotifSequenceMatchRegionP4451469 faldo:begin ?templateMotifSequenceMatchBeginP4451470 . ?templateMotifSequenceMatchBeginP4451470 faldo:position ?templateMotifSequenceMatchBeginPositionP4451465 ; faldo:reference isoform:P44514-1 . ?templateMotifSequenceProfileAlignmentOperationP4451471 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . ?targetMotifMatch72 faldo:location ?targetMotifMatchRegionMatch73 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0169075 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP44514MF_0169066 . ?targetMotifMatchRegionMatch73 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0169074 . ?targetMotifMatchRegionMatchBeginMF_0169074 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0169067 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0169075 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP44514MF_0169064, 1, (STRLEN(?templateMotifCigarP44514MF_0169064) - STRLEN(REPLACE(?templateMotifCigarP44514MF_0169064, CONCAT('^(?:-*[^-]){', STR(((69 - ?templateMotifSequenceMatchBeginPositionP4451465) + 1)), '}'), '')))), '[a-z]', '')) AS ?step176) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP44514MF_0169066, 1, (STRLEN(?targetMotifMatchCigarP44514MF_0169066) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_0169066, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step176), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP44514MF_0169066, 1, (STRLEN(?targetMotifMatchCigarP44514MF_0169066) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_0169066, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step176), '}'), '')))), '[^-]', ''))) AS ?step277) . BIND(((?step277 + ?targetMotifMatchRegionMatchBeginPositionMF_0169067) - 1) AS ?thisPositionOn14) . BIND(?thisPositionOn14 AS ?thisPositionOn15) . BIND(?this AS ?pfs1t78) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn14))) AS ?pfsb12) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfse13) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn14, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_01690a11')) AS ?annotation11) . BIND(?this AS ?pfs10) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch83 faldo:location ?templateMotifSequenceMatchRegionP4451484 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP4451486 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP44514MF_0169079 . ?templateMotifSequenceMatchRegionP4451484 faldo:begin ?templateMotifSequenceMatchBeginP4451485 . ?templateMotifSequenceMatchBeginP4451485 faldo:position ?templateMotifSequenceMatchBeginPositionP4451480 ; faldo:reference isoform:P44514-1 . ?templateMotifSequenceProfileAlignmentOperationP4451486 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . ?targetMotifMatch87 faldo:location ?targetMotifMatchRegionMatch88 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0169090 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP44514MF_0169081 . ?targetMotifMatchRegionMatch88 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0169089 . ?targetMotifMatchRegionMatchBeginMF_0169089 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0169082 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0169090 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP44514MF_0169079, 1, (STRLEN(?templateMotifCigarP44514MF_0169079) - STRLEN(REPLACE(?templateMotifCigarP44514MF_0169079, CONCAT('^(?:-*[^-]){', STR(((134 - ?templateMotifSequenceMatchBeginPositionP4451480) + 1)), '}'), '')))), '[a-z]', '')) AS ?step191) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP44514MF_0169081, 1, (STRLEN(?targetMotifMatchCigarP44514MF_0169081) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_0169081, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step191), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP44514MF_0169081, 1, (STRLEN(?targetMotifMatchCigarP44514MF_0169081) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_0169081, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step191), '}'), '')))), '[^-]', ''))) AS ?step292) . BIND(((?step292 + ?targetMotifMatchRegionMatchBeginPositionMF_0169082) - 1) AS ?thisPositionOn20) . BIND(?thisPositionOn20 AS ?thisPositionOn21) . BIND(?this AS ?pfs1t93) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn20))) AS ?pfsb18) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfse19) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn20, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_01690a17')) AS ?annotation17) . BIND(?this AS ?pfs16) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch98 faldo:location ?templateMotifSequenceMatchRegionP4451499 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP44514101 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP44514MF_0169094 . ?templateMotifSequenceMatchRegionP4451499 faldo:begin ?templateMotifSequenceMatchBeginP44514100 . ?templateMotifSequenceMatchBeginP44514100 faldo:position ?templateMotifSequenceMatchBeginPositionP4451495 ; faldo:reference isoform:P44514-1 . ?templateMotifSequenceProfileAlignmentOperationP44514101 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . ?targetMotifMatch102 faldo:location ?targetMotifMatchRegionMatch103 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01690105 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP44514MF_0169096 . ?targetMotifMatchRegionMatch103 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01690104 . ?targetMotifMatchRegionMatchBeginMF_01690104 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0169097 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01690105 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP44514MF_0169094, 1, (STRLEN(?templateMotifCigarP44514MF_0169094) - STRLEN(REPLACE(?templateMotifCigarP44514MF_0169094, CONCAT('^(?:-*[^-]){', STR(((67 - ?templateMotifSequenceMatchBeginPositionP4451495) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1106) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP44514MF_0169096, 1, (STRLEN(?targetMotifMatchCigarP44514MF_0169096) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_0169096, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1106), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP44514MF_0169096, 1, (STRLEN(?targetMotifMatchCigarP44514MF_0169096) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_0169096, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1106), '}'), '')))), '[^-]', ''))) AS ?step2107) . BIND(((?step2107 + ?targetMotifMatchRegionMatchBeginPositionMF_0169097) - 1) AS ?thisPositionOn27) . BIND(?thisPositionOn27 AS ?thisPositionOn28) . BIND(?this AS ?pfs1t108) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn27))) AS ?pfsb24) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfse25) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn27, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_01690a23')) AS ?annotation23) . BIND(?this AS ?pfs22) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch113 faldo:location ?templateMotifSequenceMatchRegionP44514114 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP44514116 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP44514MF_01690109 . ?templateMotifSequenceMatchRegionP44514114 faldo:begin ?templateMotifSequenceMatchBeginP44514115 . ?templateMotifSequenceMatchBeginP44514115 faldo:position ?templateMotifSequenceMatchBeginPositionP44514110 ; faldo:reference isoform:P44514-1 . ?templateMotifSequenceProfileAlignmentOperationP44514116 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . ?targetMotifMatch117 faldo:location ?targetMotifMatchRegionMatch118 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01690120 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP44514MF_01690111 . ?targetMotifMatchRegionMatch118 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01690119 . ?targetMotifMatchRegionMatchBeginMF_01690119 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01690112 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01690120 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP44514MF_01690109, 1, (STRLEN(?templateMotifCigarP44514MF_01690109) - STRLEN(REPLACE(?templateMotifCigarP44514MF_01690109, CONCAT('^(?:-*[^-]){', STR(((100 - ?templateMotifSequenceMatchBeginPositionP44514110) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1121) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP44514MF_01690111, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690111) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690111, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1121), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP44514MF_01690111, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690111) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690111, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1121), '}'), '')))), '[^-]', ''))) AS ?step2122) . BIND(((?step2122 + ?targetMotifMatchRegionMatchBeginPositionMF_01690112) - 1) AS ?thisPositionOn34) . BIND(?thisPositionOn34 AS ?thisPositionOn35) . BIND(?this AS ?pfs1t123) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn34))) AS ?pfsb31) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn35))) AS ?pfse32) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn34, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_01690a30')) AS ?annotation30) . BIND(?this AS ?pfs29) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch128 faldo:location ?templateMotifSequenceMatchRegionP44514129 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP44514131 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP44514MF_01690124 . ?templateMotifSequenceMatchRegionP44514129 faldo:begin ?templateMotifSequenceMatchBeginP44514130 . ?templateMotifSequenceMatchBeginP44514130 faldo:position ?templateMotifSequenceMatchBeginPositionP44514125 ; faldo:reference isoform:P44514-1 . ?templateMotifSequenceProfileAlignmentOperationP44514131 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . ?targetMotifMatch132 faldo:location ?targetMotifMatchRegionMatch133 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01690135 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP44514MF_01690126 . ?targetMotifMatchRegionMatch133 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01690134 . ?targetMotifMatchRegionMatchBeginMF_01690134 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01690127 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01690135 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP44514MF_01690124, 1, (STRLEN(?templateMotifCigarP44514MF_01690124) - STRLEN(REPLACE(?templateMotifCigarP44514MF_01690124, CONCAT('^(?:-*[^-]){', STR(((100 - ?templateMotifSequenceMatchBeginPositionP44514125) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1136) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP44514MF_01690126, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690126) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690126, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1136), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP44514MF_01690126, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690126) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690126, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1136), '}'), '')))), '[^-]', ''))) AS ?step2137) . BIND(((?step2137 + ?targetMotifMatchRegionMatchBeginPositionMF_01690127) - 1) AS ?thisPositionOn41) . BIND(?thisPositionOn41 AS ?thisPositionOn42) . BIND(?this AS ?pfs1t138) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn41))) AS ?pfsb38) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn42))) AS ?pfse39) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn41, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_01690a37')) AS ?annotation37) . BIND(?this AS ?pfs36) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch143 faldo:location ?templateMotifSequenceMatchRegionP44514144 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP44514146 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP44514MF_01690139 . ?templateMotifSequenceMatchRegionP44514144 faldo:begin ?templateMotifSequenceMatchBeginP44514145 . ?templateMotifSequenceMatchBeginP44514145 faldo:position ?templateMotifSequenceMatchBeginPositionP44514140 ; faldo:reference isoform:P44514-1 . ?templateMotifSequenceProfileAlignmentOperationP44514146 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . ?targetMotifMatch147 faldo:location ?targetMotifMatchRegionMatch148 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01690150 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP44514MF_01690141 . ?targetMotifMatchRegionMatch148 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01690149 . ?targetMotifMatchRegionMatchBeginMF_01690149 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01690142 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01690150 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP44514MF_01690139, 1, (STRLEN(?templateMotifCigarP44514MF_01690139) - STRLEN(REPLACE(?templateMotifCigarP44514MF_01690139, CONCAT('^(?:-*[^-]){', STR(((135 - ?templateMotifSequenceMatchBeginPositionP44514140) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1151) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP44514MF_01690141, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690141) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690141, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1151), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP44514MF_01690141, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690141) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690141, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1151), '}'), '')))), '[^-]', ''))) AS ?step2152) . BIND(((?step2152 + ?targetMotifMatchRegionMatchBeginPositionMF_01690142) - 1) AS ?thisPositionOn48) . BIND(?thisPositionOn48 AS ?thisPositionOn49) . BIND(?this AS ?pfs1t153) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn48))) AS ?pfsb45) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn49))) AS ?pfse46) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn48, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_01690a44')) AS ?annotation44) . BIND(?this AS ?pfs43) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch158 faldo:location ?templateMotifSequenceMatchRegionP44514159 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP44514161 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP44514MF_01690154 . ?templateMotifSequenceMatchRegionP44514159 faldo:begin ?templateMotifSequenceMatchBeginP44514160 . ?templateMotifSequenceMatchBeginP44514160 faldo:position ?templateMotifSequenceMatchBeginPositionP44514155 ; faldo:reference isoform:P44514-1 . ?templateMotifSequenceProfileAlignmentOperationP44514161 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . ?targetMotifMatch162 faldo:location ?targetMotifMatchRegionMatch163 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01690165 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP44514MF_01690156 . ?targetMotifMatchRegionMatch163 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01690164 . ?targetMotifMatchRegionMatchBeginMF_01690164 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01690157 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01690165 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP44514MF_01690154, 1, (STRLEN(?templateMotifCigarP44514MF_01690154) - STRLEN(REPLACE(?templateMotifCigarP44514MF_01690154, CONCAT('^(?:-*[^-]){', STR(((163 - ?templateMotifSequenceMatchBeginPositionP44514155) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1166) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP44514MF_01690156, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690156) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690156, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1166), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP44514MF_01690156, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690156) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690156, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1166), '}'), '')))), '[^-]', ''))) AS ?step2167) . BIND(((?step2167 + ?targetMotifMatchRegionMatchBeginPositionMF_01690157) - 1) AS ?thisPositionOn55) . BIND(?thisPositionOn55 AS ?thisPositionOn56) . BIND(?this AS ?pfs1t168) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn55))) AS ?pfsb52) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn56))) AS ?pfse53) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn55, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_01690a51')) AS ?annotation51) . BIND(?this AS ?pfs50) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch173 faldo:location ?templateMotifSequenceMatchRegionP44514174 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP44514176 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP44514MF_01690169 . ?templateMotifSequenceMatchRegionP44514174 faldo:begin ?templateMotifSequenceMatchBeginP44514175 . ?templateMotifSequenceMatchBeginP44514175 faldo:position ?templateMotifSequenceMatchBeginPositionP44514170 ; faldo:reference isoform:P44514-1 . ?templateMotifSequenceProfileAlignmentOperationP44514176 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . ?targetMotifMatch177 faldo:location ?targetMotifMatchRegionMatch178 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01690180 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP44514MF_01690171 . ?targetMotifMatchRegionMatch178 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01690179 . ?targetMotifMatchRegionMatchBeginMF_01690179 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01690172 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01690180 edam:has_input signature:MF_01690 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP44514MF_01690169, 1, (STRLEN(?templateMotifCigarP44514MF_01690169) - STRLEN(REPLACE(?templateMotifCigarP44514MF_01690169, CONCAT('^(?:-*[^-]){', STR(((349 - ?templateMotifSequenceMatchBeginPositionP44514170) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1181) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP44514MF_01690171, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690171) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690171, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1181), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP44514MF_01690171, 1, (STRLEN(?targetMotifMatchCigarP44514MF_01690171) - STRLEN(REPLACE(?targetMotifMatchCigarP44514MF_01690171, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1181), '}'), '')))), '[^-]', ''))) AS ?step2182) . BIND(((?step2182 + ?targetMotifMatchRegionMatchBeginPositionMF_01690172) - 1) AS ?thisPositionOn62) . BIND(?thisPositionOn62 AS ?thisPositionOn63) . BIND(?this AS ?pfs1t183) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn62))) AS ?pfsb59) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn63))) AS ?pfse60) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn62, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_01690a58')) AS ?annotation58) . BIND(?this AS ?pfs57) . } }