CONSTRUCT { _:851686 up:source unirule:MF_03175 . _:851687 up:source unirule:MF_03175 . _:851688 up:source unirule:MF_03175 . _:851689 up:source unirule:MF_03175 . _:851690 up:source unirule:MF_03175 . _:851691 up:source unirule:MF_03175 . _:851692 up:source unirule:MF_03175 . _:851693 up:source unirule:MF_03175 . _:851694 up:source unirule:MF_03175 . _:851695 up:source unirule:MF_03175 . _:851696 up:source unirule:MF_03175 . _:851697 up:source unirule:MF_03175 . _:851698 up:source unirule:MF_03175 . _:851699 up:source unirule:MF_03175 . _:851700 up:source unirule:MF_03175 . _:851701 up:source unirule:MF_03175 . _:851702 up:source unirule:MF_03175 . _:851703 up:source unirule:MF_03175 . _:851704 up:source unirule:MF_03175 . _:851705 up:source unirule:MF_03175 . _:851706 up:source unirule:MF_03175 . _:851707 up:source unirule:MF_03175 . _:851708 up:source unirule:MF_03175 . _:851709 up:source unirule:MF_03175 . ?this up:alternativeName ?name1 ; up:annotation ?annotation2 , ?annotation3 , ?annotation5 , ?annotation6 ; up:classifiedWith GO:0004239 , GO:0046872 , GO:0070006 , keyword:31 , keyword:378 , keyword:479 , keyword:645 , keyword:963 ; up:recommendedName ?name0 . ?name0 up:ecName '3.4.11.18' ; up:fullName 'Methionine aminopeptidase 2' ; up:shortName 'MAP 2' , 'MetAP 2' ; rdf:type up:Structured_Name . ?name1 up:fullName 'Peptidase M' ; rdf:type up:Structured_Name . ?annotation2 a up:Function_Annotation ; rdfs:comment 'Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).' . ?annotation3 up:activity ?activity4 ; rdf:type up:Catalytic_Activity_Annotation . ?activity4 up:enzymeClass <http://purl.uniprot.org/enzyme/3.4.11.18>. ?annotation5 up:cofactor chebi:29033 , chebi:29035 , chebi:29105 , chebi:48828 ; rdf:type up:Cofactor_Annotation ; rdfs:comment 'Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.' . ?annotation6 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.' . ?case7 up:classifiedWith keyword:325 . ?pfs10 up:annotation ?annotation11 . ?annotation11 faldo:begin ?pfsb12 ; faldo:end ?pfse13 ; up:ligand ?ligand14 ; rdf:type up:Binding_Site_Annotation . ?pfsb12 faldo:position ?thisPositionOn15 ; rdf:type faldo:ExactPosition . ?pfse13 faldo:position ?thisPositionOn16 ; rdf:type faldo:ExactPosition . ?ligand14 rdfs:subClassOf chebi:60240 . ?pfs17 up:annotation ?annotation18 . ?annotation18 faldo:begin ?pfsb19 ; faldo:end ?pfse20 ; up:ligand ?ligand21 ; rdf:type up:Binding_Site_Annotation . ?pfsb19 faldo:position ?thisPositionOn22 ; rdf:type faldo:ExactPosition . ?pfse20 faldo:position ?thisPositionOn23 ; rdf:type faldo:ExactPosition . ?ligand21 rdfs:subClassOf chebi:60240 . ?pfs24 up:annotation ?annotation25 . ?annotation25 faldo:begin ?pfsb26 ; faldo:end ?pfse27 ; up:ligand ?ligand28 ; rdf:type up:Binding_Site_Annotation . ?pfsb26 faldo:position ?thisPositionOn29 ; rdf:type faldo:ExactPosition . ?pfse27 faldo:position ?thisPositionOn30 ; rdf:type faldo:ExactPosition . ?ligand28 rdfs:subClassOf chebi:60240 . ?pfs31 up:annotation ?annotation32 . ?annotation32 faldo:begin ?pfsb33 ; faldo:end ?pfse34 ; up:ligand ?ligand35 ; rdf:type up:Binding_Site_Annotation . ?pfsb33 faldo:position ?thisPositionOn36 ; rdf:type faldo:ExactPosition . ?pfse34 faldo:position ?thisPositionOn37 ; rdf:type faldo:ExactPosition . ?ligand35 rdfs:subClassOf chebi:60240 . ?pfs38 up:annotation ?annotation39 . ?annotation39 faldo:begin ?pfsb40 ; faldo:end ?pfse41 ; up:ligand ?ligand42 ; rdf:type up:Binding_Site_Annotation . ?pfsb40 faldo:position ?thisPositionOn43 ; rdf:type faldo:ExactPosition . ?pfse41 faldo:position ?thisPositionOn44 ; rdf:type faldo:ExactPosition . ?ligand42 rdfs:subClassOf chebi:60240 . ?pfs45 up:annotation ?annotation46 . ?annotation46 faldo:begin ?pfsb47 ; faldo:end ?pfse48 ; up:ligand ?ligand49 ; rdf:type up:Binding_Site_Annotation . ?pfsb47 faldo:position ?thisPositionOn50 ; rdf:type faldo:ExactPosition . ?pfse48 faldo:position ?thisPositionOn51 ; rdf:type faldo:ExactPosition . ?ligand49 rdfs:subClassOf chebi:60240 . ?pfs52 up:annotation ?annotation53 . ?annotation53 faldo:begin ?pfsb54 ; faldo:end ?pfse55 ; up:ligand ?ligand56 ; rdf:type up:Binding_Site_Annotation . ?pfsb54 faldo:position ?thisPositionOn57 ; rdf:type faldo:ExactPosition . ?pfse55 faldo:position ?thisPositionOn58 ; rdf:type faldo:ExactPosition . ?ligand56 rdfs:subClassOf chebi:60240 . ?pfs59 up:annotation ?annotation60 . ?annotation60 faldo:begin ?pfsb61 ; faldo:end ?pfse62 ; up:ligand ?ligand63 ; rdf:type up:Binding_Site_Annotation . ?pfsb61 faldo:position ?thisPositionOn65 ; rdf:type faldo:ExactPosition . ?pfse62 faldo:position ?thisPositionOn66 ; rdf:type faldo:ExactPosition . ?ligand63 rdfs:subClassOf ?molecule64 . ?molecule64 rdfs:label 'substrate' . ?pfs67 up:annotation ?annotation68 . ?annotation68 faldo:begin ?pfsb69 ; faldo:end ?pfse70 ; up:ligand ?ligand71 ; rdf:type up:Binding_Site_Annotation . ?pfsb69 faldo:position ?thisPositionOn73 ; rdf:type faldo:ExactPosition . ?pfse70 faldo:position ?thisPositionOn74 ; rdf:type faldo:ExactPosition . ?ligand71 rdfs:subClassOf ?molecule72 . ?molecule72 rdfs:label 'substrate' . _:851710 a rdf:Statement ; up:attribution _:851686 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:851711 a rdf:Statement ; up:attribution _:851687 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name1 . _:851712 a rdf:Statement ; up:attribution _:851688 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation2 . _:851713 a rdf:Statement ; up:attribution _:851689 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation3 . _:851714 a rdf:Statement ; up:attribution _:851690 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation5 . _:851715 a rdf:Statement ; up:attribution _:851691 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation6 . _:851716 a rdf:Statement ; up:attribution _:851692 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:31 . _:851717 a rdf:Statement ; up:attribution _:851693 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:963 . _:851718 a rdf:Statement ; up:attribution _:851694 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:378 . _:851719 a rdf:Statement ; up:attribution _:851695 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:479 . _:851720 a rdf:Statement ; up:attribution _:851696 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:645 . _:851721 a rdf:Statement ; up:attribution _:851697 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0046872 . _:851722 a rdf:Statement ; up:attribution _:851698 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0070006 . _:851723 a rdf:Statement ; up:attribution _:851699 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0004239 . _:851724 a rdf:Statement ; up:attribution _:851700 ; rdf:subject ?case7 ; rdf:predicate up:classifiedWith ; rdf:object keyword:325 . _:851725 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs10 ; rdf:predicate up:annotation ; rdf:object ?annotation11 . _:851726 a rdf:Statement ; up:attribution _:851701 ; rdf:subject ?pfs10 ; rdf:predicate up:annotation ; rdf:object ?annotation11 . _:851727 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs17 ; rdf:predicate up:annotation ; rdf:object ?annotation18 . _:851728 a rdf:Statement ; up:attribution _:851702 ; rdf:subject ?pfs17 ; rdf:predicate up:annotation ; rdf:object ?annotation18 . _:851729 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs24 ; rdf:predicate up:annotation ; rdf:object ?annotation25 . _:851730 a rdf:Statement ; up:attribution _:851703 ; rdf:subject ?pfs24 ; rdf:predicate up:annotation ; rdf:object ?annotation25 . _:851731 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs31 ; rdf:predicate up:annotation ; rdf:object ?annotation32 . _:851732 a rdf:Statement ; up:attribution _:851704 ; rdf:subject ?pfs31 ; rdf:predicate up:annotation ; rdf:object ?annotation32 . _:851733 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs38 ; rdf:predicate up:annotation ; rdf:object ?annotation39 . _:851734 a rdf:Statement ; up:attribution _:851705 ; rdf:subject ?pfs38 ; rdf:predicate up:annotation ; rdf:object ?annotation39 . _:851735 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs45 ; rdf:predicate up:annotation ; rdf:object ?annotation46 . _:851736 a rdf:Statement ; up:attribution _:851706 ; rdf:subject ?pfs45 ; rdf:predicate up:annotation ; rdf:object ?annotation46 . _:851737 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs52 ; rdf:predicate up:annotation ; rdf:object ?annotation53 . _:851738 a rdf:Statement ; up:attribution _:851707 ; rdf:subject ?pfs52 ; rdf:predicate up:annotation ; rdf:object ?annotation53 . _:851739 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs59 ; rdf:predicate up:annotation ; rdf:object ?annotation60 . _:851740 a rdf:Statement ; up:attribution _:851708 ; rdf:subject ?pfs59 ; rdf:predicate up:annotation ; rdf:object ?annotation60 . _:851741 a rdf:Statement ; up:source unirule:MF_03175 ; rdf:subject ?pfs67 ; rdf:predicate up:annotation ; rdf:object ?annotation68 . _:851742 a rdf:Statement ; up:attribution _:851709 ; rdf:subject ?pfs67 ; rdf:predicate up:annotation ; rdf:object ?annotation68 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_03175 #Rule MF_03175 Created by:ipedruzz on:2013-06-05 Modified by:ecastro on:2023-12-07 ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_03175 . ?thisOrganism rdfs:subClassOf+ taxon:2759 . BIND(URI(CONCAT(STR(?this), '#MF_03175a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_03175a1')) AS ?name1) . BIND(URI(CONCAT(STR(?this), '#MF_03175a2')) AS ?annotation2) . BIND(URI(CONCAT(STR(?this), '#MF_03175a3')) AS ?annotation3) . BIND(URI(CONCAT(STR(?this), '#MF_03175a5')) AS ?annotation5) . BIND(URI(CONCAT(STR(?this), '#MF_03175a6')) AS ?annotation6) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch79 faldo:location ?templateMotifSequenceMatchRegionP5057980 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP5057982 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_0317575 . ?templateMotifSequenceMatchRegionP5057980 faldo:begin ?templateMotifSequenceMatchBeginP5057981 . ?templateMotifSequenceMatchBeginP5057981 faldo:position ?templateMotifSequenceMatchBeginPositionP5057976 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP5057982 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch83 faldo:location ?targetMotifMatchRegionMatch84 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0317586 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_0317577 . ?targetMotifMatchRegionMatch84 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0317585 . ?targetMotifMatchRegionMatchBeginMF_0317585 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0317578 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0317586 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_0317575, 1, (STRLEN(?templateMotifCigarP50579MF_0317575) - STRLEN(REPLACE(?templateMotifCigarP50579MF_0317575, CONCAT('^(?:-*[^-]){', STR(((251 - ?templateMotifSequenceMatchBeginPositionP5057976) + 1)), '}'), '')))), '[a-z]', '')) AS ?step187) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_0317577, 1, (STRLEN(?targetMotifMatchCigarP50579MF_0317577) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_0317577, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step187), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_0317577, 1, (STRLEN(?targetMotifMatchCigarP50579MF_0317577) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_0317577, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step187), '}'), '')))), '[^-]', ''))) AS ?step288) . BIND(((?step288 + ?targetMotifMatchRegionMatchBeginPositionMF_0317578) - 1) AS ?thisPositionOn15) . BIND(?thisPositionOn15 AS ?thisPositionOn16) . BIND(?this AS ?pfs1t89) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfsb12) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn16))) AS ?pfse13) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn15, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a11')) AS ?annotation11) . BIND(?this AS ?pfs10) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch94 faldo:location ?templateMotifSequenceMatchRegionP5057995 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP5057997 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_0317590 . ?templateMotifSequenceMatchRegionP5057995 faldo:begin ?templateMotifSequenceMatchBeginP5057996 . ?templateMotifSequenceMatchBeginP5057996 faldo:position ?templateMotifSequenceMatchBeginPositionP5057991 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP5057997 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch98 faldo:location ?targetMotifMatchRegionMatch99 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_03175101 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_0317592 . ?targetMotifMatchRegionMatch99 faldo:begin ?targetMotifMatchRegionMatchBeginMF_03175100 . ?targetMotifMatchRegionMatchBeginMF_03175100 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0317593 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_03175101 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_0317590, 1, (STRLEN(?templateMotifCigarP50579MF_0317590) - STRLEN(REPLACE(?templateMotifCigarP50579MF_0317590, CONCAT('^(?:-*[^-]){', STR(((262 - ?templateMotifSequenceMatchBeginPositionP5057991) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1102) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_0317592, 1, (STRLEN(?targetMotifMatchCigarP50579MF_0317592) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_0317592, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1102), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_0317592, 1, (STRLEN(?targetMotifMatchCigarP50579MF_0317592) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_0317592, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1102), '}'), '')))), '[^-]', ''))) AS ?step2103) . BIND(((?step2103 + ?targetMotifMatchRegionMatchBeginPositionMF_0317593) - 1) AS ?thisPositionOn22) . BIND(?thisPositionOn22 AS ?thisPositionOn23) . BIND(?this AS ?pfs1t104) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfsb19) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn23))) AS ?pfse20) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn22, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a18')) AS ?annotation18) . BIND(?this AS ?pfs17) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch109 faldo:location ?templateMotifSequenceMatchRegionP50579110 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP50579112 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_03175105 . ?templateMotifSequenceMatchRegionP50579110 faldo:begin ?templateMotifSequenceMatchBeginP50579111 . ?templateMotifSequenceMatchBeginP50579111 faldo:position ?templateMotifSequenceMatchBeginPositionP50579106 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP50579112 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch113 faldo:location ?targetMotifMatchRegionMatch114 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_03175116 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_03175107 . ?targetMotifMatchRegionMatch114 faldo:begin ?targetMotifMatchRegionMatchBeginMF_03175115 . ?targetMotifMatchRegionMatchBeginMF_03175115 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_03175108 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_03175116 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_03175105, 1, (STRLEN(?templateMotifCigarP50579MF_03175105) - STRLEN(REPLACE(?templateMotifCigarP50579MF_03175105, CONCAT('^(?:-*[^-]){', STR(((262 - ?templateMotifSequenceMatchBeginPositionP50579106) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1117) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_03175107, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175107) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175107, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1117), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_03175107, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175107) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175107, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1117), '}'), '')))), '[^-]', ''))) AS ?step2118) . BIND(((?step2118 + ?targetMotifMatchRegionMatchBeginPositionMF_03175108) - 1) AS ?thisPositionOn29) . BIND(?thisPositionOn29 AS ?thisPositionOn30) . BIND(?this AS ?pfs1t119) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn29))) AS ?pfsb26) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn30))) AS ?pfse27) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn29, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a25')) AS ?annotation25) . BIND(?this AS ?pfs24) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch124 faldo:location ?templateMotifSequenceMatchRegionP50579125 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP50579127 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_03175120 . ?templateMotifSequenceMatchRegionP50579125 faldo:begin ?templateMotifSequenceMatchBeginP50579126 . ?templateMotifSequenceMatchBeginP50579126 faldo:position ?templateMotifSequenceMatchBeginPositionP50579121 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP50579127 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch128 faldo:location ?targetMotifMatchRegionMatch129 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_03175131 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_03175122 . ?targetMotifMatchRegionMatch129 faldo:begin ?targetMotifMatchRegionMatchBeginMF_03175130 . ?targetMotifMatchRegionMatchBeginMF_03175130 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_03175123 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_03175131 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_03175120, 1, (STRLEN(?templateMotifCigarP50579MF_03175120) - STRLEN(REPLACE(?templateMotifCigarP50579MF_03175120, CONCAT('^(?:-*[^-]){', STR(((331 - ?templateMotifSequenceMatchBeginPositionP50579121) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1132) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_03175122, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175122) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175122, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1132), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_03175122, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175122) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175122, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1132), '}'), '')))), '[^-]', ''))) AS ?step2133) . BIND(((?step2133 + ?targetMotifMatchRegionMatchBeginPositionMF_03175123) - 1) AS ?thisPositionOn36) . BIND(?thisPositionOn36 AS ?thisPositionOn37) . BIND(?this AS ?pfs1t134) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn36))) AS ?pfsb33) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn37))) AS ?pfse34) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn36, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a32')) AS ?annotation32) . BIND(?this AS ?pfs31) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch139 faldo:location ?templateMotifSequenceMatchRegionP50579140 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP50579142 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_03175135 . ?templateMotifSequenceMatchRegionP50579140 faldo:begin ?templateMotifSequenceMatchBeginP50579141 . ?templateMotifSequenceMatchBeginP50579141 faldo:position ?templateMotifSequenceMatchBeginPositionP50579136 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP50579142 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch143 faldo:location ?targetMotifMatchRegionMatch144 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_03175146 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_03175137 . ?targetMotifMatchRegionMatch144 faldo:begin ?targetMotifMatchRegionMatchBeginMF_03175145 . ?targetMotifMatchRegionMatchBeginMF_03175145 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_03175138 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_03175146 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_03175135, 1, (STRLEN(?templateMotifCigarP50579MF_03175135) - STRLEN(REPLACE(?templateMotifCigarP50579MF_03175135, CONCAT('^(?:-*[^-]){', STR(((364 - ?templateMotifSequenceMatchBeginPositionP50579136) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1147) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_03175137, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175137) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175137, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1147), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_03175137, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175137) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175137, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1147), '}'), '')))), '[^-]', ''))) AS ?step2148) . BIND(((?step2148 + ?targetMotifMatchRegionMatchBeginPositionMF_03175138) - 1) AS ?thisPositionOn43) . BIND(?thisPositionOn43 AS ?thisPositionOn44) . BIND(?this AS ?pfs1t149) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn43))) AS ?pfsb40) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn44))) AS ?pfse41) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn43, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a39')) AS ?annotation39) . BIND(?this AS ?pfs38) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch154 faldo:location ?templateMotifSequenceMatchRegionP50579155 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP50579157 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_03175150 . ?templateMotifSequenceMatchRegionP50579155 faldo:begin ?templateMotifSequenceMatchBeginP50579156 . ?templateMotifSequenceMatchBeginP50579156 faldo:position ?templateMotifSequenceMatchBeginPositionP50579151 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP50579157 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch158 faldo:location ?targetMotifMatchRegionMatch159 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_03175161 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_03175152 . ?targetMotifMatchRegionMatch159 faldo:begin ?targetMotifMatchRegionMatchBeginMF_03175160 . ?targetMotifMatchRegionMatchBeginMF_03175160 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_03175153 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_03175161 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_03175150, 1, (STRLEN(?templateMotifCigarP50579MF_03175150) - STRLEN(REPLACE(?templateMotifCigarP50579MF_03175150, CONCAT('^(?:-*[^-]){', STR(((459 - ?templateMotifSequenceMatchBeginPositionP50579151) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1162) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_03175152, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175152) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175152, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1162), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_03175152, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175152) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175152, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1162), '}'), '')))), '[^-]', ''))) AS ?step2163) . BIND(((?step2163 + ?targetMotifMatchRegionMatchBeginPositionMF_03175153) - 1) AS ?thisPositionOn50) . BIND(?thisPositionOn50 AS ?thisPositionOn51) . BIND(?this AS ?pfs1t164) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn50))) AS ?pfsb47) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn51))) AS ?pfse48) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn50, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a46')) AS ?annotation46) . BIND(?this AS ?pfs45) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch169 faldo:location ?templateMotifSequenceMatchRegionP50579170 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP50579172 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_03175165 . ?templateMotifSequenceMatchRegionP50579170 faldo:begin ?templateMotifSequenceMatchBeginP50579171 . ?templateMotifSequenceMatchBeginP50579171 faldo:position ?templateMotifSequenceMatchBeginPositionP50579166 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP50579172 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch173 faldo:location ?targetMotifMatchRegionMatch174 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_03175176 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_03175167 . ?targetMotifMatchRegionMatch174 faldo:begin ?targetMotifMatchRegionMatchBeginMF_03175175 . ?targetMotifMatchRegionMatchBeginMF_03175175 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_03175168 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_03175176 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_03175165, 1, (STRLEN(?templateMotifCigarP50579MF_03175165) - STRLEN(REPLACE(?templateMotifCigarP50579MF_03175165, CONCAT('^(?:-*[^-]){', STR(((459 - ?templateMotifSequenceMatchBeginPositionP50579166) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1177) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_03175167, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175167) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175167, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1177), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_03175167, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175167) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175167, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1177), '}'), '')))), '[^-]', ''))) AS ?step2178) . BIND(((?step2178 + ?targetMotifMatchRegionMatchBeginPositionMF_03175168) - 1) AS ?thisPositionOn57) . BIND(?thisPositionOn57 AS ?thisPositionOn58) . BIND(?this AS ?pfs1t179) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn57))) AS ?pfsb54) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn58))) AS ?pfse55) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn57, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a53')) AS ?annotation53) . BIND(?this AS ?pfs52) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch184 faldo:location ?templateMotifSequenceMatchRegionP50579185 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP50579187 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_03175180 . ?templateMotifSequenceMatchRegionP50579185 faldo:begin ?templateMotifSequenceMatchBeginP50579186 . ?templateMotifSequenceMatchBeginP50579186 faldo:position ?templateMotifSequenceMatchBeginPositionP50579181 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP50579187 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch188 faldo:location ?targetMotifMatchRegionMatch189 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_03175191 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_03175182 . ?targetMotifMatchRegionMatch189 faldo:begin ?targetMotifMatchRegionMatchBeginMF_03175190 . ?targetMotifMatchRegionMatchBeginMF_03175190 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_03175183 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_03175191 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_03175180, 1, (STRLEN(?templateMotifCigarP50579MF_03175180) - STRLEN(REPLACE(?templateMotifCigarP50579MF_03175180, CONCAT('^(?:-*[^-]){', STR(((231 - ?templateMotifSequenceMatchBeginPositionP50579181) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1192) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_03175182, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175182) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175182, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1192), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_03175182, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175182) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175182, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1192), '}'), '')))), '[^-]', ''))) AS ?step2193) . BIND(((?step2193 + ?targetMotifMatchRegionMatchBeginPositionMF_03175183) - 1) AS ?thisPositionOn65) . BIND(?thisPositionOn65 AS ?thisPositionOn66) . BIND(?this AS ?pfs1t194) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn65))) AS ?pfsb61) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn66))) AS ?pfse62) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn65, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a60')) AS ?annotation60) . BIND(?this AS ?pfs59) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch199 faldo:location ?templateMotifSequenceMatchRegionP50579200 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP50579202 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP50579MF_03175195 . ?templateMotifSequenceMatchRegionP50579200 faldo:begin ?templateMotifSequenceMatchBeginP50579201 . ?templateMotifSequenceMatchBeginP50579201 faldo:position ?templateMotifSequenceMatchBeginPositionP50579196 ; faldo:reference isoform:P50579-1 . ?templateMotifSequenceProfileAlignmentOperationP50579202 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . ?targetMotifMatch203 faldo:location ?targetMotifMatchRegionMatch204 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_03175206 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP50579MF_03175197 . ?targetMotifMatchRegionMatch204 faldo:begin ?targetMotifMatchRegionMatchBeginMF_03175205 . ?targetMotifMatchRegionMatchBeginMF_03175205 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_03175198 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_03175206 edam:has_input signature:MF_03175 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP50579MF_03175195, 1, (STRLEN(?templateMotifCigarP50579MF_03175195) - STRLEN(REPLACE(?templateMotifCigarP50579MF_03175195, CONCAT('^(?:-*[^-]){', STR(((339 - ?templateMotifSequenceMatchBeginPositionP50579196) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1207) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP50579MF_03175197, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175197) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175197, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1207), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP50579MF_03175197, 1, (STRLEN(?targetMotifMatchCigarP50579MF_03175197) - STRLEN(REPLACE(?targetMotifMatchCigarP50579MF_03175197, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1207), '}'), '')))), '[^-]', ''))) AS ?step2208) . BIND(((?step2208 + ?targetMotifMatchRegionMatchBeginPositionMF_03175198) - 1) AS ?thisPositionOn73) . BIND(?thisPositionOn73 AS ?thisPositionOn74) . BIND(?this AS ?pfs1t209) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn73))) AS ?pfsb69) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn74))) AS ?pfse70) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn73, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_03175a68')) AS ?annotation68) . BIND(?this AS ?pfs67) . } OPTIONAL { ?this a up:Protein . ?this up:organism ?thisOrganism . ?thisOrganism rdfs:subClassOf+ taxon:7742 . BIND(?this AS ?case7) . } OPTIONAL { ?this a up:Protein . ?this up:organism ?thisOrganism . ?thisOrganism rdfs:subClassOf+ taxon:147537 . BIND(?this AS ?case8) . } OPTIONAL { ?this a up:Protein . ?this up:organism ?thisOrganism . FILTER (! (EXISTS { ?thisOrganism rdfs:subClassOf+ taxon:7742 . })) . BIND(?this AS ?case9) . } }