CONSTRUCT { _:886882 up:source unirule:MF_03218 . _:886883 up:source unirule:MF_03218 . _:886884 up:source unirule:MF_03218 . _:886885 up:source unirule:MF_03218 . _:886886 up:source unirule:MF_03218 . _:886887 up:source unirule:MF_03218 . _:886888 up:source unirule:MF_03218 . _:886889 up:source unirule:MF_03218 . _:886890 up:source unirule:MF_03218 . _:886891 up:source unirule:MF_03218 . _:886892 up:source unirule:MF_03218 . _:886893 up:source unirule:MF_03218 . _:886894 up:source unirule:MF_03218 . _:886895 up:source unirule:MF_03218 . _:886896 up:source unirule:MF_03218 . _:886897 up:source unirule:MF_03218 . _:886898 up:source unirule:MF_03218 . _:886899 up:source unirule:MF_03218 . _:886900 up:source unirule:MF_03218 . _:886901 up:source unirule:MF_03218 . _:886902 up:source unirule:MF_03218 . _:886903 up:source unirule:MF_03218 . _:886904 up:source unirule:MF_03218 . _:886905 up:source unirule:MF_03218 . _:886906 up:source unirule:MF_03218 . _:886907 up:source unirule:MF_03218 . _:886908 up:source unirule:MF_03218 . _:886909 up:source unirule:MF_03218 . _:886910 up:source unirule:MF_03218 . _:886911 up:source unirule:MF_03218 . _:886912 up:source unirule:MF_03218 . ?this up:alternativeName ?name1 , ?name2 ; up:annotation ?annotation3 , ?annotation4 , ?annotation6 ; up:classifiedWith GO:0002099 , GO:0005737 , GO:0008479 , keyword:328 , keyword:808 , keyword:819 , keyword:963 ; up:recommendedName ?name0 . ?name0 up:ecName '2.4.2.64' ; up:fullName 'Queuine tRNA-ribosyltransferase catalytic subunit 1' ; rdf:type up:Structured_Name . ?name1 up:fullName 'Guanine insertion enzyme' ; rdf:type up:Structured_Name . ?name2 up:fullName 'tRNA-guanine transglycosylase' ; rdf:type up:Structured_Name . ?annotation3 a up:Function_Annotation ; rdfs:comment "Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product." . ?annotation4 up:activity ?activity5 ; rdf:type up:Catalytic_Activity_Annotation . ?activity5 up:catalyticActivity <http://rdf.rhea-db.org/16633>; up:enzymeClass <http://purl.uniprot.org/enzyme/2.4.2.64>. ?annotation6 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the queuine tRNA-ribosyltransferase family.' . ?case7 up:classifiedWith keyword:479 , keyword:862 . ?case8 up:classifiedWith GO:0005741 , keyword:1000 , keyword:472 , keyword:496 . ?pfs11 up:annotation ?annotation12 , ?annotation18 , ?annotation24 , ?annotation30 . ?annotation12 faldo:begin ?pfsb13 ; faldo:end ?pfse14 ; up:ligand ?ligand15 ; rdf:type up:Binding_Site_Annotation . ?pfsb13 faldo:position ?thisPositionOn16 ; rdf:type faldo:ExactPosition . ?pfse14 faldo:position ?thisPositionOn17 ; rdf:type faldo:ExactPosition . ?ligand15 rdfs:subClassOf chebi:29105 . ?annotation18 faldo:begin ?pfsb19 ; faldo:end ?pfse20 ; up:ligand ?ligand21 ; rdf:type up:Binding_Site_Annotation . ?pfsb19 faldo:position ?thisPositionOn22 ; rdf:type faldo:ExactPosition . ?pfse20 faldo:position ?thisPositionOn23 ; rdf:type faldo:ExactPosition . ?ligand21 rdfs:subClassOf chebi:29105 . ?annotation24 faldo:begin ?pfsb25 ; faldo:end ?pfse26 ; up:ligand ?ligand27 ; rdf:type up:Binding_Site_Annotation . ?pfsb25 faldo:position ?thisPositionOn28 ; rdf:type faldo:ExactPosition . ?pfse26 faldo:position ?thisPositionOn29 ; rdf:type faldo:ExactPosition . ?ligand27 rdfs:subClassOf chebi:29105 . ?annotation30 faldo:begin ?pfsb31 ; faldo:end ?pfse32 ; up:ligand ?ligand33 ; rdf:type up:Binding_Site_Annotation . ?pfsb31 faldo:position ?thisPositionOn34 ; rdf:type faldo:ExactPosition . ?pfse32 faldo:position ?thisPositionOn35 ; rdf:type faldo:ExactPosition . ?ligand33 rdfs:subClassOf chebi:29105 . ?pfs36 up:annotation ?annotation37 . ?annotation37 faldo:begin ?pfsb38 ; faldo:end ?pfse39 ; up:ligand ?ligand40 ; rdf:type up:Binding_Site_Annotation . ?pfsb38 faldo:position ?thisPositionOn42 ; rdf:type faldo:ExactPosition . ?pfse39 faldo:position ?thisPositionOn43 ; rdf:type faldo:ExactPosition . ?ligand40 rdfs:subClassOf ?molecule41 . ?molecule41 rdfs:label 'substrate' . ?pfs44 up:annotation ?annotation45 . ?annotation45 faldo:begin ?pfsb46 ; faldo:end ?pfse47 ; rdf:type up:Region_Annotation ; rdfs:comment 'RNA binding' . ?pfsb46 faldo:position ?thisPositionOn48 ; rdf:type faldo:ExactPosition . ?pfse47 faldo:position ?thisPositionOn49 ; rdf:type faldo:ExactPosition . ?pfs50 up:annotation ?annotation51 . ?annotation51 faldo:begin ?pfsb52 ; faldo:end ?pfse53 ; rdf:type up:Region_Annotation ; rdfs:comment 'RNA binding; important for wobble base 34 recognition' . ?pfsb52 faldo:position ?thisPositionOn54 ; rdf:type faldo:ExactPosition . ?pfse53 faldo:position ?thisPositionOn55 ; rdf:type faldo:ExactPosition . ?pfs56 up:annotation ?annotation57 . ?annotation57 faldo:begin ?pfsb58 ; faldo:end ?pfse59 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Proton acceptor' . ?pfsb58 faldo:position ?thisPositionOn60 ; rdf:type faldo:ExactPosition . ?pfse59 faldo:position ?thisPositionOn61 ; rdf:type faldo:ExactPosition . ?pfs62 up:annotation ?annotation63 . ?annotation63 faldo:begin ?pfsb64 ; faldo:end ?pfse65 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Nucleophile' . ?pfsb64 faldo:position ?thisPositionOn66 ; rdf:type faldo:ExactPosition . ?pfse65 faldo:position ?thisPositionOn67 ; rdf:type faldo:ExactPosition . ?pfs68 up:annotation ?annotation69 . ?annotation69 faldo:begin ?pfsb70 ; faldo:end ?pfse71 ; up:ligand ?ligand72 ; rdf:type up:Binding_Site_Annotation . ?pfsb70 faldo:position ?thisPositionOn74 ; rdf:type faldo:ExactPosition . ?pfse71 faldo:position ?thisPositionOn75 ; rdf:type faldo:ExactPosition . ?ligand72 rdfs:subClassOf ?molecule73 . ?molecule73 rdfs:label 'substrate' . ?pfs76 up:annotation ?annotation77 . ?annotation77 faldo:begin ?pfsb78 ; faldo:end ?pfse79 ; up:ligand ?ligand80 ; rdf:type up:Binding_Site_Annotation . ?pfsb78 faldo:position ?thisPositionOn82 ; rdf:type faldo:ExactPosition . ?pfse79 faldo:position ?thisPositionOn83 ; rdf:type faldo:ExactPosition . ?ligand80 rdfs:subClassOf ?molecule81 . ?molecule81 rdfs:label 'substrate' . ?pfs84 up:annotation ?annotation85 . ?annotation85 faldo:begin ?pfsb86 ; faldo:end ?pfse87 ; up:ligand ?ligand88 ; rdf:type up:Binding_Site_Annotation . ?pfsb86 faldo:position ?thisPositionOn90 ; rdf:type faldo:ExactPosition . ?pfse87 faldo:position ?thisPositionOn91 ; rdf:type faldo:ExactPosition . ?ligand88 rdfs:subClassOf ?molecule89 . ?molecule89 rdfs:label 'substrate' . _:886913 a rdf:Statement ; up:attribution _:886882 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:886914 a rdf:Statement ; up:attribution _:886883 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name1 . _:886915 a rdf:Statement ; up:attribution _:886884 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name2 . _:886916 a rdf:Statement ; up:attribution _:886885 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation3 . _:886917 a rdf:Statement ; up:attribution _:886886 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation4 . _:886918 a rdf:Statement ; up:attribution _:886887 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation6 . _:886919 a rdf:Statement ; up:attribution _:886888 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:963 . _:886920 a rdf:Statement ; up:attribution _:886889 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:328 . _:886921 a rdf:Statement ; up:attribution _:886890 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:808 . _:886922 a rdf:Statement ; up:attribution _:886891 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:819 . _:886923 a rdf:Statement ; up:attribution _:886892 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0005737 . _:886924 a rdf:Statement ; up:attribution _:886893 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0008479 . _:886925 a rdf:Statement ; up:attribution _:886894 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0002099 . _:886926 a rdf:Statement ; up:attribution _:886895 ; rdf:subject ?case7 ; rdf:predicate up:classifiedWith ; rdf:object keyword:479 . _:886927 a rdf:Statement ; up:attribution _:886896 ; rdf:subject ?case7 ; rdf:predicate up:classifiedWith ; rdf:object keyword:862 . _:886928 a rdf:Statement ; up:attribution _:886897 ; rdf:subject ?case8 ; rdf:predicate up:classifiedWith ; rdf:object keyword:496 . _:886929 a rdf:Statement ; up:attribution _:886898 ; rdf:subject ?case8 ; rdf:predicate up:classifiedWith ; rdf:object keyword:1000 . _:886930 a rdf:Statement ; up:attribution _:886899 ; rdf:subject ?case8 ; rdf:predicate up:classifiedWith ; rdf:object keyword:472 . _:886931 a rdf:Statement ; up:attribution _:886900 ; rdf:subject ?case8 ; rdf:predicate up:classifiedWith ; rdf:object GO:0005741 . _:886932 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:886933 a rdf:Statement ; up:attribution _:886901 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:886934 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation18 . _:886935 a rdf:Statement ; up:attribution _:886902 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation18 . _:886936 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation24 . _:886937 a rdf:Statement ; up:attribution _:886903 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation24 . _:886938 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation30 . _:886939 a rdf:Statement ; up:attribution _:886904 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation30 . _:886940 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs36 ; rdf:predicate up:annotation ; rdf:object ?annotation37 . _:886941 a rdf:Statement ; up:attribution _:886905 ; rdf:subject ?pfs36 ; rdf:predicate up:annotation ; rdf:object ?annotation37 . _:886942 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs44 ; rdf:predicate up:annotation ; rdf:object ?annotation45 . _:886943 a rdf:Statement ; up:attribution _:886906 ; rdf:subject ?pfs44 ; rdf:predicate up:annotation ; rdf:object ?annotation45 . _:886944 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs50 ; rdf:predicate up:annotation ; rdf:object ?annotation51 . _:886945 a rdf:Statement ; up:attribution _:886907 ; rdf:subject ?pfs50 ; rdf:predicate up:annotation ; rdf:object ?annotation51 . _:886946 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs56 ; rdf:predicate up:annotation ; rdf:object ?annotation57 . _:886947 a rdf:Statement ; up:attribution _:886908 ; rdf:subject ?pfs56 ; rdf:predicate up:annotation ; rdf:object ?annotation57 . _:886948 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs62 ; rdf:predicate up:annotation ; rdf:object ?annotation63 . _:886949 a rdf:Statement ; up:attribution _:886909 ; rdf:subject ?pfs62 ; rdf:predicate up:annotation ; rdf:object ?annotation63 . _:886950 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs68 ; rdf:predicate up:annotation ; rdf:object ?annotation69 . _:886951 a rdf:Statement ; up:attribution _:886910 ; rdf:subject ?pfs68 ; rdf:predicate up:annotation ; rdf:object ?annotation69 . _:886952 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs76 ; rdf:predicate up:annotation ; rdf:object ?annotation77 . _:886953 a rdf:Statement ; up:attribution _:886911 ; rdf:subject ?pfs76 ; rdf:predicate up:annotation ; rdf:object ?annotation77 . _:886954 a rdf:Statement ; up:source unirule:MF_03218 ; rdf:subject ?pfs84 ; rdf:predicate up:annotation ; rdf:object ?annotation85 . _:886955 a rdf:Statement ; up:attribution _:886912 ; rdf:subject ?pfs84 ; rdf:predicate up:annotation ; rdf:object ?annotation85 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_03218 #Rule MF_03218 Created by:? on:2016-07-22 Modified by:Catherine Rivoire on:2025-06-13 ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_00168 . ?thisOrganism rdfs:subClassOf+ taxon:2759 . BIND(URI(CONCAT(STR(?this), '#MF_03218a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_03218a1')) AS ?name1) . BIND(URI(CONCAT(STR(?this), '#MF_03218a2')) AS ?name2) . BIND(URI(CONCAT(STR(?this), '#MF_03218a3')) AS ?annotation3) . BIND(URI(CONCAT(STR(?this), '#MF_03218a4')) AS ?annotation4) . BIND(URI(CONCAT(STR(?this), '#MF_03218a6')) AS ?annotation6) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch96 faldo:location ?templateMotifSequenceMatchRegionP2872097 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP2872099 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_0016892 . ?templateMotifSequenceMatchRegionP2872097 faldo:begin ?templateMotifSequenceMatchBeginP2872098 . ?templateMotifSequenceMatchBeginP2872098 faldo:position ?templateMotifSequenceMatchBeginPositionP2872093 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP2872099 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch100 faldo:location ?targetMotifMatchRegionMatch101 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168103 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_0016894 . ?targetMotifMatchRegionMatch101 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168102 . ?targetMotifMatchRegionMatchBeginMF_00168102 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0016895 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168103 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(?this AS ?tagFTGRP_1) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_0016892, 1, (STRLEN(?templateMotifCigarP28720MF_0016892) - STRLEN(REPLACE(?templateMotifCigarP28720MF_0016892, CONCAT('^(?:-*[^-]){', STR(((318 - ?templateMotifSequenceMatchBeginPositionP2872093) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1104) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_0016894, 1, (STRLEN(?targetMotifMatchCigarP28720MF_0016894) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_0016894, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1104), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_0016894, 1, (STRLEN(?targetMotifMatchCigarP28720MF_0016894) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_0016894, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1104), '}'), '')))), '[^-]', ''))) AS ?step2105) . BIND(((?step2105 + ?targetMotifMatchRegionMatchBeginPositionMF_0016895) - 1) AS ?thisPositionOn16) . BIND(?thisPositionOn16 AS ?thisPositionOn17) . BIND(?this AS ?pfs1t106) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn16))) AS ?pfsb13) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn17))) AS ?pfse14) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn16, 1) = 'C')) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_0016892, 1, (STRLEN(?templateMotifCigarP28720MF_0016892) - STRLEN(REPLACE(?templateMotifCigarP28720MF_0016892, CONCAT('^(?:-*[^-]){', STR(((320 - ?templateMotifSequenceMatchBeginPositionP2872093) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1107) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_0016894, 1, (STRLEN(?targetMotifMatchCigarP28720MF_0016894) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_0016894, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1107), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_0016894, 1, (STRLEN(?targetMotifMatchCigarP28720MF_0016894) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_0016894, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1107), '}'), '')))), '[^-]', ''))) AS ?step2108) . BIND(((?step2108 + ?targetMotifMatchRegionMatchBeginPositionMF_0016895) - 1) AS ?thisPositionOn22) . BIND(?thisPositionOn22 AS ?thisPositionOn23) . BIND(?this AS ?pfs1t109) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfsb19) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn23))) AS ?pfse20) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn22, 1) = 'C')) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_0016892, 1, (STRLEN(?templateMotifCigarP28720MF_0016892) - STRLEN(REPLACE(?templateMotifCigarP28720MF_0016892, CONCAT('^(?:-*[^-]){', STR(((323 - ?templateMotifSequenceMatchBeginPositionP2872093) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1110) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_0016894, 1, (STRLEN(?targetMotifMatchCigarP28720MF_0016894) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_0016894, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1110), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_0016894, 1, (STRLEN(?targetMotifMatchCigarP28720MF_0016894) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_0016894, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1110), '}'), '')))), '[^-]', ''))) AS ?step2111) . BIND(((?step2111 + ?targetMotifMatchRegionMatchBeginPositionMF_0016895) - 1) AS ?thisPositionOn28) . BIND(?thisPositionOn28 AS ?thisPositionOn29) . BIND(?this AS ?pfs1t112) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfsb25) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn29))) AS ?pfse26) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn28, 1) = 'C')) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_0016892, 1, (STRLEN(?templateMotifCigarP28720MF_0016892) - STRLEN(REPLACE(?templateMotifCigarP28720MF_0016892, CONCAT('^(?:-*[^-]){', STR(((349 - ?templateMotifSequenceMatchBeginPositionP2872093) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1113) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_0016894, 1, (STRLEN(?targetMotifMatchCigarP28720MF_0016894) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_0016894, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1113), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_0016894, 1, (STRLEN(?targetMotifMatchCigarP28720MF_0016894) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_0016894, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1113), '}'), '')))), '[^-]', ''))) AS ?step2114) . BIND(((?step2114 + ?targetMotifMatchRegionMatchBeginPositionMF_0016895) - 1) AS ?thisPositionOn34) . BIND(?thisPositionOn34 AS ?thisPositionOn35) . BIND(?this AS ?pfs1t115) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn34))) AS ?pfsb31) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn35))) AS ?pfse32) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn34, 1) = 'H')) . BIND(?this AS ?pfs11) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch120 faldo:location ?templateMotifSequenceMatchRegionP28720121 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP28720123 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_00168116 . ?templateMotifSequenceMatchRegionP28720121 faldo:begin ?templateMotifSequenceMatchBeginP28720122 . ?templateMotifSequenceMatchBeginP28720122 faldo:position ?templateMotifSequenceMatchBeginPositionP28720117 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP28720123 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch124 faldo:location ?targetMotifMatchRegionMatch125 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168127 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_00168118 . ?targetMotifMatchRegionMatch125 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168126 . ?targetMotifMatchRegionMatchBeginMF_00168126 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00168119 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168127 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168116, 1, (STRLEN(?templateMotifCigarP28720MF_00168116) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168116, CONCAT('^(?:-*[^-]){', STR(((102 - ?templateMotifSequenceMatchBeginPositionP28720117) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1128) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168118, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168118) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168118, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1128), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168118, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168118) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168118, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1128), '}'), '')))), '[^-]', ''))) AS ?step2129) . BIND(((?step2129 + ?targetMotifMatchRegionMatchBeginPositionMF_00168119) - 1) AS ?thisPositionOn42) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168116, 1, (STRLEN(?templateMotifCigarP28720MF_00168116) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168116, CONCAT('^(?:-*[^-]){', STR(((106 - ?templateMotifSequenceMatchBeginPositionP28720117) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1130) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168118, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168118) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168118, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1130), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168118, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168118) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168118, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1130), '}'), '')))), '[^-]', ''))) AS ?step2131) . BIND(((?step2131 + ?targetMotifMatchRegionMatchBeginPositionMF_00168119) - 1) AS ?thisPositionOn43) . BIND(?this AS ?pfs2t132) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn42))) AS ?pfsb38) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn43))) AS ?pfse39) . FILTER (REGEX('DSGG[FY]', SUBSTR(?thisSequenceValue, ?thisPositionOn42, (?thisPositionOn43 - ?thisPositionOn42)))) . BIND(URI(CONCAT(STR(?this), '#MF_03218a37')) AS ?annotation37) . BIND(?this AS ?pfs36) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch137 faldo:location ?templateMotifSequenceMatchRegionP28720138 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP28720140 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_00168133 . ?templateMotifSequenceMatchRegionP28720138 faldo:begin ?templateMotifSequenceMatchBeginP28720139 . ?templateMotifSequenceMatchBeginP28720139 faldo:position ?templateMotifSequenceMatchBeginPositionP28720134 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP28720140 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch141 faldo:location ?targetMotifMatchRegionMatch142 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168144 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_00168135 . ?targetMotifMatchRegionMatch142 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168143 . ?targetMotifMatchRegionMatchBeginMF_00168143 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00168136 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168144 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168133, 1, (STRLEN(?templateMotifCigarP28720MF_00168133) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168133, CONCAT('^(?:-*[^-]){', STR(((261 - ?templateMotifSequenceMatchBeginPositionP28720134) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1145) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168135, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168135) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168135, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1145), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168135, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168135) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168135, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1145), '}'), '')))), '[^-]', ''))) AS ?step2146) . BIND(((?step2146 + ?targetMotifMatchRegionMatchBeginPositionMF_00168136) - 1) AS ?thisPositionOn48) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168133, 1, (STRLEN(?templateMotifCigarP28720MF_00168133) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168133, CONCAT('^(?:-*[^-]){', STR(((267 - ?templateMotifSequenceMatchBeginPositionP28720134) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1147) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168135, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168135) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168135, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1147), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168135, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168135) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168135, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1147), '}'), '')))), '[^-]', ''))) AS ?step2148) . BIND(((?step2148 + ?targetMotifMatchRegionMatchBeginPositionMF_00168136) - 1) AS ?thisPositionOn49) . BIND(?this AS ?pfs2t149) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn48))) AS ?pfsb46) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn49))) AS ?pfse47) . FILTER (REGEX('G[VIG]G[ARNDCQEGHILKMFPSTWYVBZJUOX]{4)', SUBSTR(?thisSequenceValue, ?thisPositionOn48, (?thisPositionOn49 - ?thisPositionOn48)))) . BIND(URI(CONCAT(STR(?this), '#MF_03218a45')) AS ?annotation45) . BIND(?this AS ?pfs44) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch154 faldo:location ?templateMotifSequenceMatchRegionP28720155 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP28720157 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_00168150 . ?templateMotifSequenceMatchRegionP28720155 faldo:begin ?templateMotifSequenceMatchBeginP28720156 . ?templateMotifSequenceMatchBeginP28720156 faldo:position ?templateMotifSequenceMatchBeginPositionP28720151 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP28720157 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch158 faldo:location ?targetMotifMatchRegionMatch159 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168161 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_00168152 . ?targetMotifMatchRegionMatch159 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168160 . ?targetMotifMatchRegionMatchBeginMF_00168160 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00168153 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168161 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168150, 1, (STRLEN(?templateMotifCigarP28720MF_00168150) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168150, CONCAT('^(?:-*[^-]){', STR(((285 - ?templateMotifSequenceMatchBeginPositionP28720151) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1162) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168152, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168152) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168152, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1162), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168152, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168152) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168152, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1162), '}'), '')))), '[^-]', ''))) AS ?step2163) . BIND(((?step2163 + ?targetMotifMatchRegionMatchBeginPositionMF_00168153) - 1) AS ?thisPositionOn54) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168150, 1, (STRLEN(?templateMotifCigarP28720MF_00168150) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168150, CONCAT('^(?:-*[^-]){', STR(((289 - ?templateMotifSequenceMatchBeginPositionP28720151) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1164) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168152, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168152) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168152, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1164), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168152, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168152) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168152, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1164), '}'), '')))), '[^-]', ''))) AS ?step2165) . BIND(((?step2165 + ?targetMotifMatchRegionMatchBeginPositionMF_00168153) - 1) AS ?thisPositionOn55) . BIND(?this AS ?pfs2t166) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn54))) AS ?pfsb52) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn55))) AS ?pfse53) . FILTER (REGEX('[TA][RK][ARNDCQEGHILKMFPSTWYVBZJUOX]{2)R', SUBSTR(?thisSequenceValue, ?thisPositionOn54, (?thisPositionOn55 - ?thisPositionOn54)))) . BIND(URI(CONCAT(STR(?this), '#MF_03218a51')) AS ?annotation51) . BIND(?this AS ?pfs50) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch171 faldo:location ?templateMotifSequenceMatchRegionP28720172 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP28720174 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_00168167 . ?templateMotifSequenceMatchRegionP28720172 faldo:begin ?templateMotifSequenceMatchBeginP28720173 . ?templateMotifSequenceMatchBeginP28720173 faldo:position ?templateMotifSequenceMatchBeginPositionP28720168 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP28720174 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch175 faldo:location ?targetMotifMatchRegionMatch176 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168178 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_00168169 . ?targetMotifMatchRegionMatch176 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168177 . ?targetMotifMatchRegionMatchBeginMF_00168177 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00168170 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168178 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168167, 1, (STRLEN(?templateMotifCigarP28720MF_00168167) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168167, CONCAT('^(?:-*[^-]){', STR(((102 - ?templateMotifSequenceMatchBeginPositionP28720168) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1179) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168169, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168169) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168169, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1179), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168169, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168169) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168169, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1179), '}'), '')))), '[^-]', ''))) AS ?step2180) . BIND(((?step2180 + ?targetMotifMatchRegionMatchBeginPositionMF_00168170) - 1) AS ?thisPositionOn60) . BIND(?thisPositionOn60 AS ?thisPositionOn61) . BIND(?this AS ?pfs2t181) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn60))) AS ?pfsb58) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn61))) AS ?pfse59) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn60, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_03218a57')) AS ?annotation57) . BIND(?this AS ?pfs56) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch186 faldo:location ?templateMotifSequenceMatchRegionP28720187 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP28720189 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_00168182 . ?templateMotifSequenceMatchRegionP28720187 faldo:begin ?templateMotifSequenceMatchBeginP28720188 . ?templateMotifSequenceMatchBeginP28720188 faldo:position ?templateMotifSequenceMatchBeginPositionP28720183 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP28720189 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch190 faldo:location ?targetMotifMatchRegionMatch191 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168193 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_00168184 . ?targetMotifMatchRegionMatch191 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168192 . ?targetMotifMatchRegionMatchBeginMF_00168192 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00168185 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168193 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168182, 1, (STRLEN(?templateMotifCigarP28720MF_00168182) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168182, CONCAT('^(?:-*[^-]){', STR(((280 - ?templateMotifSequenceMatchBeginPositionP28720183) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1194) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168184, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168184) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168184, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1194), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168184, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168184) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168184, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1194), '}'), '')))), '[^-]', ''))) AS ?step2195) . BIND(((?step2195 + ?targetMotifMatchRegionMatchBeginPositionMF_00168185) - 1) AS ?thisPositionOn66) . BIND(?thisPositionOn66 AS ?thisPositionOn67) . BIND(?this AS ?pfs2t196) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn66))) AS ?pfsb64) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn67))) AS ?pfse65) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn66, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_03218a63')) AS ?annotation63) . BIND(?this AS ?pfs62) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch201 faldo:location ?templateMotifSequenceMatchRegionP28720202 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP28720204 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_00168197 . ?templateMotifSequenceMatchRegionP28720202 faldo:begin ?templateMotifSequenceMatchBeginP28720203 . ?templateMotifSequenceMatchBeginP28720203 faldo:position ?templateMotifSequenceMatchBeginPositionP28720198 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP28720204 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch205 faldo:location ?targetMotifMatchRegionMatch206 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168208 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_00168199 . ?targetMotifMatchRegionMatch206 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168207 . ?targetMotifMatchRegionMatchBeginMF_00168207 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00168200 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168208 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168197, 1, (STRLEN(?templateMotifCigarP28720MF_00168197) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168197, CONCAT('^(?:-*[^-]){', STR(((156 - ?templateMotifSequenceMatchBeginPositionP28720198) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1209) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168199, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168199) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168199, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1209), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168199, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168199) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168199, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1209), '}'), '')))), '[^-]', ''))) AS ?step2210) . BIND(((?step2210 + ?targetMotifMatchRegionMatchBeginPositionMF_00168200) - 1) AS ?thisPositionOn74) . BIND(?thisPositionOn74 AS ?thisPositionOn75) . BIND(?this AS ?pfs2t211) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn74))) AS ?pfsb70) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn75))) AS ?pfse71) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn74, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_03218a69')) AS ?annotation69) . BIND(?this AS ?pfs68) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch216 faldo:location ?templateMotifSequenceMatchRegionP28720217 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP28720219 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_00168212 . ?templateMotifSequenceMatchRegionP28720217 faldo:begin ?templateMotifSequenceMatchBeginP28720218 . ?templateMotifSequenceMatchBeginP28720218 faldo:position ?templateMotifSequenceMatchBeginPositionP28720213 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP28720219 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch220 faldo:location ?targetMotifMatchRegionMatch221 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168223 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_00168214 . ?targetMotifMatchRegionMatch221 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168222 . ?targetMotifMatchRegionMatchBeginMF_00168222 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00168215 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168223 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168212, 1, (STRLEN(?templateMotifCigarP28720MF_00168212) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168212, CONCAT('^(?:-*[^-]){', STR(((203 - ?templateMotifSequenceMatchBeginPositionP28720213) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1224) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168214, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168214) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168214, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1224), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168214, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168214) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168214, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1224), '}'), '')))), '[^-]', ''))) AS ?step2225) . BIND(((?step2225 + ?targetMotifMatchRegionMatchBeginPositionMF_00168215) - 1) AS ?thisPositionOn82) . BIND(?thisPositionOn82 AS ?thisPositionOn83) . BIND(?this AS ?pfs2t226) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn82))) AS ?pfsb78) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn83))) AS ?pfse79) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn82, 1) = 'Q')) . BIND(URI(CONCAT(STR(?this), '#MF_03218a77')) AS ?annotation77) . BIND(?this AS ?pfs76) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch231 faldo:location ?templateMotifSequenceMatchRegionP28720232 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP28720234 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP28720MF_00168227 . ?templateMotifSequenceMatchRegionP28720232 faldo:begin ?templateMotifSequenceMatchBeginP28720233 . ?templateMotifSequenceMatchBeginP28720233 faldo:position ?templateMotifSequenceMatchBeginPositionP28720228 ; faldo:reference isoform:P28720-1 . ?templateMotifSequenceProfileAlignmentOperationP28720234 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . ?targetMotifMatch235 faldo:location ?targetMotifMatchRegionMatch236 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00168238 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP28720MF_00168229 . ?targetMotifMatchRegionMatch236 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00168237 . ?targetMotifMatchRegionMatchBeginMF_00168237 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00168230 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00168238 edam:has_input signature:MF_00168 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP28720MF_00168227, 1, (STRLEN(?templateMotifCigarP28720MF_00168227) - STRLEN(REPLACE(?templateMotifCigarP28720MF_00168227, CONCAT('^(?:-*[^-]){', STR(((230 - ?templateMotifSequenceMatchBeginPositionP28720228) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1239) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP28720MF_00168229, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168229) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168229, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1239), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP28720MF_00168229, 1, (STRLEN(?targetMotifMatchCigarP28720MF_00168229) - STRLEN(REPLACE(?targetMotifMatchCigarP28720MF_00168229, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1239), '}'), '')))), '[^-]', ''))) AS ?step2240) . BIND(((?step2240 + ?targetMotifMatchRegionMatchBeginPositionMF_00168230) - 1) AS ?thisPositionOn90) . BIND(?thisPositionOn90 AS ?thisPositionOn91) . BIND(?this AS ?pfs2t241) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn90))) AS ?pfsb86) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn91))) AS ?pfse87) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn90, 1) = 'G')) . BIND(URI(CONCAT(STR(?this), '#MF_03218a85')) AS ?annotation85) . BIND(?this AS ?pfs84) . } OPTIONAL { ?this a up:Protein . BIND(?this AS ?caseWithTag242) . } BIND(IF(BOUND(?tagFTGRP_1), ?caseWithTag242, ?UNBOUND_VARIABLE) AS ?case7) . OPTIONAL { ?this a up:Protein . ?this up:organism ?thisOrganism . ?thisOrganism rdfs:subClassOf+ taxon:7742 . BIND(?this AS ?case8) . } OPTIONAL { ?this a up:Protein . ?this up:organism ?thisOrganism . ?thisOrganism rdfs:subClassOf+ taxon:6237 . BIND(?this AS ?case9) . } OPTIONAL { ?this a up:Protein . ?this up:organism ?thisOrganism . FILTER (! (EXISTS { ?thisOrganism rdfs:subClassOf+ taxon:7742 . })) . BIND(?this AS ?case10) . } }