CONSTRUCT { _:7320 up:source unirule:MF_00016 . _:7321 up:source unirule:MF_00016 . _:7322 up:source unirule:MF_00016 . _:7323 up:source unirule:MF_00016 . _:7324 up:source unirule:MF_00016 . _:7325 up:source unirule:MF_00016 . _:7326 up:source unirule:MF_00016 . _:7327 up:source unirule:MF_00016 . _:7328 up:source unirule:MF_00016 . _:7329 up:source unirule:MF_00016 . _:7330 up:source unirule:MF_00016 . _:7331 up:source unirule:MF_00016 . _:7332 up:source unirule:MF_00016 . _:7333 up:source unirule:MF_00016 . _:7334 up:source unirule:MF_00016 . _:7335 up:source unirule:MF_00016 . _:7336 up:source unirule:MF_00016 . _:7337 up:source unirule:MF_00016 . _:7338 up:source unirule:MF_00016 . _:7339 up:source unirule:MF_00016 . _:7340 up:source unirule:MF_00016 . _:7341 up:source unirule:MF_00016 . _:7342 up:source unirule:MF_00016 . _:7343 up:source unirule:MF_00016 . _:7344 up:source unirule:MF_00016 . _:7345 up:source unirule:MF_00016 . _:7346 up:source unirule:MF_00016 . _:7347 up:source unirule:MF_00016 . _:7348 up:source unirule:MF_00016 . _:7349 up:source unirule:MF_00016 . _:7350 up:source unirule:MF_00016 . _:7351 up:source unirule:MF_00016 . _:7352 up:source unirule:MF_00016 . _:7353 up:source unirule:MF_00016 . _:7354 up:source unirule:MF_00016 . _:7355 up:source unirule:MF_00016 . _:7356 up:source unirule:MF_00016 . _:7357 up:source unirule:MF_00016 . _:7358 up:source unirule:MF_00016 . _:7359 up:source unirule:MF_00016 . _:7360 up:source unirule:MF_00016 . ?this up:annotation ?annotation2 , ?annotation3 , ?annotation5 , ?annotation6 , ?annotation8 , ?annotation9 ; up:classifiedWith GO:0000400 , GO:0005524 , GO:0006281 , GO:0006310 , GO:0048476 , keyword:227 , keyword:233 , keyword:234 , keyword:238 , keyword:378 , keyword:547 , keyword:67 , keyword:963 ; up:recommendedName ?name0 . ?name0 up:ecName '3.6.4.-' ; up:fullName 'Holliday junction branch migration complex subunit RuvB' ; rdf:type up:Structured_Name . ?gene1 skos:prefLabel 'ruvB' . ?annotation2 a up:Function_Annotation ; rdfs:comment 'The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.' . ?annotation3 up:activity ?activity4 ; rdf:type up:Catalytic_Activity_Annotation . ?activity4 up:catalyticActivity <http://rdf.rhea-db.org/13065>. ?annotation5 a up:Subunit_Annotation ; rdfs:comment 'Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.' . ?annotation6 a up:Subcellular_Location_Annotation . ?annotation6li7 up:cellularComponent <http://purl.uniprot.org/locations/null>. ?annotation8 a up:Domain_Annotation ; rdfs:comment 'Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.' . ?annotation9 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the RuvB family.' . ?case10 up:classifiedWith GO:0009432 , keyword:742 . ?pfs11 up:annotation ?annotation12 . ?annotation12 faldo:begin ?pfsb13 ; faldo:end ?pfse14 ; rdf:type up:Region_Annotation ; rdfs:comment 'Large ATPase domain (RuvB-L)' . ?pfsb13 faldo:position ?thisPositionOn15 ; rdf:type faldo:ExactPosition . ?pfse14 faldo:position ?thisPositionOn16 ; rdf:type faldo:ExactPosition . ?pfs17 up:annotation ?annotation18 . ?annotation18 faldo:begin ?pfsb19 ; faldo:end ?pfse20 ; rdf:type up:Region_Annotation ; rdfs:comment 'Small ATPAse domain (RuvB-S)' . ?pfsb19 faldo:position ?thisPositionOn21 ; rdf:type faldo:ExactPosition . ?pfse20 faldo:position ?thisPositionOn22 ; rdf:type faldo:ExactPosition . ?pfs23 up:annotation ?annotation24 . ?annotation24 faldo:begin ?pfsb25 ; faldo:end ?pfse26 ; rdf:type up:Region_Annotation ; rdfs:comment 'Head domain (RuvB-H)' . ?pfsb25 faldo:position ?thisPositionOn27 ; rdf:type faldo:ExactPosition . ?pfse26 faldo:position ?thisPositionOn28 ; rdf:type faldo:ExactPosition . ?pfs29 up:annotation ?annotation30 . ?annotation30 faldo:begin ?pfsb31 ; faldo:end ?pfse32 ; up:ligand ?ligand33 ; rdf:type up:Binding_Site_Annotation . ?pfsb31 faldo:position ?thisPositionOn34 ; rdf:type faldo:ExactPosition . ?pfse32 faldo:position ?thisPositionOn35 ; rdf:type faldo:ExactPosition . ?ligand33 rdfs:subClassOf chebi:30616 . ?pfs36 up:annotation ?annotation37 . ?annotation37 faldo:begin ?pfsb38 ; faldo:end ?pfse39 ; up:ligand ?ligand40 ; rdf:type up:Binding_Site_Annotation . ?pfsb38 faldo:position ?thisPositionOn41 ; rdf:type faldo:ExactPosition . ?pfse39 faldo:position ?thisPositionOn42 ; rdf:type faldo:ExactPosition . ?ligand40 rdfs:subClassOf chebi:30616 . ?pfs43 up:annotation ?annotation44 . ?annotation44 faldo:begin ?pfsb45 ; faldo:end ?pfse46 ; up:ligand ?ligand47 ; rdf:type up:Binding_Site_Annotation . ?pfsb45 faldo:position ?thisPositionOn48 ; rdf:type faldo:ExactPosition . ?pfse46 faldo:position ?thisPositionOn49 ; rdf:type faldo:ExactPosition . ?ligand47 rdfs:subClassOf chebi:30616 . ?pfs50 up:annotation ?annotation51 . ?annotation51 faldo:begin ?pfsb52 ; faldo:end ?pfse53 ; up:ligand ?ligand54 ; rdf:type up:Binding_Site_Annotation . ?pfsb52 faldo:position ?thisPositionOn55 ; rdf:type faldo:ExactPosition . ?pfse53 faldo:position ?thisPositionOn56 ; rdf:type faldo:ExactPosition . ?ligand54 rdfs:subClassOf chebi:30616 . ?pfs57 up:annotation ?annotation58 . ?annotation58 faldo:begin ?pfsb59 ; faldo:end ?pfse60 ; up:ligand ?ligand61 ; rdf:type up:Binding_Site_Annotation . ?pfsb59 faldo:position ?thisPositionOn62 ; rdf:type faldo:ExactPosition . ?pfse60 faldo:position ?thisPositionOn63 ; rdf:type faldo:ExactPosition . ?ligand61 rdfs:subClassOf chebi:30616 . ?pfs64 up:annotation ?annotation65 . ?annotation65 faldo:begin ?pfsb66 ; faldo:end ?pfse67 ; up:ligand ?ligand68 ; rdf:type up:Binding_Site_Annotation . ?pfsb66 faldo:position ?thisPositionOn69 ; rdf:type faldo:ExactPosition . ?pfse67 faldo:position ?thisPositionOn70 ; rdf:type faldo:ExactPosition . ?ligand68 rdfs:subClassOf chebi:18420 . ?pfs71 up:annotation ?annotation72 . ?annotation72 faldo:begin ?pfsb73 ; faldo:end ?pfse74 ; up:ligand ?ligand75 ; rdf:type up:Binding_Site_Annotation . ?pfsb73 faldo:position ?thisPositionOn76 ; rdf:type faldo:ExactPosition . ?pfse74 faldo:position ?thisPositionOn77 ; rdf:type faldo:ExactPosition . ?ligand75 rdfs:subClassOf chebi:30616 . ?pfs78 up:annotation ?annotation79 . ?annotation79 faldo:begin ?pfsb80 ; faldo:end ?pfse81 ; up:ligand ?ligand82 ; rdf:type up:Binding_Site_Annotation . ?pfsb80 faldo:position ?thisPositionOn83 ; rdf:type faldo:ExactPosition . ?pfse81 faldo:position ?thisPositionOn84 ; rdf:type faldo:ExactPosition . ?ligand82 rdfs:subClassOf chebi:30616 . ?pfs85 up:annotation ?annotation86 . ?annotation86 faldo:begin ?pfsb87 ; faldo:end ?pfse88 ; up:ligand ?ligand89 ; rdf:type up:Binding_Site_Annotation . ?pfsb87 faldo:position ?thisPositionOn90 ; rdf:type faldo:ExactPosition . ?pfse88 faldo:position ?thisPositionOn91 ; rdf:type faldo:ExactPosition . ?ligand89 rdfs:subClassOf chebi:30616 . ?pfs92 up:annotation ?annotation93 . ?annotation93 faldo:begin ?pfsb94 ; faldo:end ?pfse95 ; up:ligand ?ligand96 ; rdf:type up:Binding_Site_Annotation . ?pfsb94 faldo:position ?thisPositionOn97 ; rdf:type faldo:ExactPosition . ?pfse95 faldo:position ?thisPositionOn98 ; rdf:type faldo:ExactPosition . ?ligand96 rdfs:subClassOf chebi:30616 . ?pfs99 up:annotation ?annotation100 . ?annotation100 faldo:begin ?pfsb101 ; faldo:end ?pfse102 ; up:ligand ?ligand103 ; rdf:type up:Binding_Site_Annotation . ?pfsb101 faldo:position ?thisPositionOn104 ; rdf:type faldo:ExactPosition . ?pfse102 faldo:position ?thisPositionOn105 ; rdf:type faldo:ExactPosition . ?ligand103 rdfs:subClassOf chebi:30616 . ?pfs106 up:annotation ?annotation107 . ?annotation107 faldo:begin ?pfsb108 ; faldo:end ?pfse109 ; up:ligand ?ligand110 ; rdf:type up:Binding_Site_Annotation . ?pfsb108 faldo:position ?thisPositionOn111 ; rdf:type faldo:ExactPosition . ?pfse109 faldo:position ?thisPositionOn112 ; rdf:type faldo:ExactPosition . ?ligand110 rdfs:subClassOf chebi:16991 . ?pfs113 up:annotation ?annotation114 . ?annotation114 faldo:begin ?pfsb115 ; faldo:end ?pfse116 ; up:ligand ?ligand117 ; rdf:type up:Binding_Site_Annotation . ?pfsb115 faldo:position ?thisPositionOn118 ; rdf:type faldo:ExactPosition . ?pfse116 faldo:position ?thisPositionOn119 ; rdf:type faldo:ExactPosition . ?ligand117 rdfs:subClassOf chebi:16991 . ?pfs120 up:annotation ?annotation121 . ?annotation121 faldo:begin ?pfsb122 ; faldo:end ?pfse123 ; up:ligand ?ligand124 ; rdf:type up:Binding_Site_Annotation . ?pfsb122 faldo:position ?thisPositionOn125 ; rdf:type faldo:ExactPosition . ?pfse123 faldo:position ?thisPositionOn126 ; rdf:type faldo:ExactPosition . ?ligand124 rdfs:subClassOf chebi:16991 . ?pfs127 up:annotation ?annotation128 . ?annotation128 faldo:begin ?pfsb129 ; faldo:end ?pfse130 ; up:ligand ?ligand131 ; rdf:type up:Binding_Site_Annotation . ?pfsb129 faldo:position ?thisPositionOn132 ; rdf:type faldo:ExactPosition . ?pfse130 faldo:position ?thisPositionOn133 ; rdf:type faldo:ExactPosition . ?ligand131 rdfs:subClassOf chebi:16991 . _:7361 a rdf:Statement ; up:attribution _:7320 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:7362 a rdf:Statement ; up:attribution _:7321 ; rdf:subject ?gene1 ; rdf:predicate up:encodedBy ; rdf:object ?gene1 . _:7363 a rdf:Statement ; up:attribution _:7322 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation2 . _:7364 a rdf:Statement ; up:attribution _:7323 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation3 . _:7365 a rdf:Statement ; up:attribution _:7324 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation5 . _:7366 a rdf:Statement ; up:attribution _:7325 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation6 . _:7367 a rdf:Statement ; up:attribution _:7326 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation8 . _:7368 a rdf:Statement ; up:attribution _:7327 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation9 . _:7369 a rdf:Statement ; up:attribution _:7328 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:963 . _:7370 a rdf:Statement ; up:attribution _:7329 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:227 . _:7371 a rdf:Statement ; up:attribution _:7330 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:234 . _:7372 a rdf:Statement ; up:attribution _:7331 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:238 . _:7373 a rdf:Statement ; up:attribution _:7332 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:67 . _:7374 a rdf:Statement ; up:attribution _:7333 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:547 . _:7375 a rdf:Statement ; up:attribution _:7334 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:233 . _:7376 a rdf:Statement ; up:attribution _:7335 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:378 . _:7377 a rdf:Statement ; up:attribution _:7336 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0005524 . _:7378 a rdf:Statement ; up:attribution _:7337 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0000400 . _:7379 a rdf:Statement ; up:attribution _:7338 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0048476 . _:7380 a rdf:Statement ; up:attribution _:7339 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0006310 . _:7381 a rdf:Statement ; up:attribution _:7340 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0006281 . _:7382 a rdf:Statement ; up:attribution _:7341 ; rdf:subject ?case10 ; rdf:predicate up:classifiedWith ; rdf:object keyword:742 . _:7383 a rdf:Statement ; up:attribution _:7342 ; rdf:subject ?case10 ; rdf:predicate up:classifiedWith ; rdf:object GO:0009432 . _:7384 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:7385 a rdf:Statement ; up:attribution _:7343 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:7386 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs17 ; rdf:predicate up:annotation ; rdf:object ?annotation18 . _:7387 a rdf:Statement ; up:attribution _:7344 ; rdf:subject ?pfs17 ; rdf:predicate up:annotation ; rdf:object ?annotation18 . _:7388 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs23 ; rdf:predicate up:annotation ; rdf:object ?annotation24 . _:7389 a rdf:Statement ; up:attribution _:7345 ; rdf:subject ?pfs23 ; rdf:predicate up:annotation ; rdf:object ?annotation24 . _:7390 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs29 ; rdf:predicate up:annotation ; rdf:object ?annotation30 . _:7391 a rdf:Statement ; up:attribution _:7346 ; rdf:subject ?pfs29 ; rdf:predicate up:annotation ; rdf:object ?annotation30 . _:7392 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs36 ; rdf:predicate up:annotation ; rdf:object ?annotation37 . _:7393 a rdf:Statement ; up:attribution _:7347 ; rdf:subject ?pfs36 ; rdf:predicate up:annotation ; rdf:object ?annotation37 . _:7394 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs43 ; rdf:predicate up:annotation ; rdf:object ?annotation44 . _:7395 a rdf:Statement ; up:attribution _:7348 ; rdf:subject ?pfs43 ; rdf:predicate up:annotation ; rdf:object ?annotation44 . _:7396 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs50 ; rdf:predicate up:annotation ; rdf:object ?annotation51 . _:7397 a rdf:Statement ; up:attribution _:7349 ; rdf:subject ?pfs50 ; rdf:predicate up:annotation ; rdf:object ?annotation51 . _:7398 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs57 ; rdf:predicate up:annotation ; rdf:object ?annotation58 . _:7399 a rdf:Statement ; up:attribution _:7350 ; rdf:subject ?pfs57 ; rdf:predicate up:annotation ; rdf:object ?annotation58 . _:7400 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs64 ; rdf:predicate up:annotation ; rdf:object ?annotation65 . _:7401 a rdf:Statement ; up:attribution _:7351 ; rdf:subject ?pfs64 ; rdf:predicate up:annotation ; rdf:object ?annotation65 . _:7402 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs71 ; rdf:predicate up:annotation ; rdf:object ?annotation72 . _:7403 a rdf:Statement ; up:attribution _:7352 ; rdf:subject ?pfs71 ; rdf:predicate up:annotation ; rdf:object ?annotation72 . _:7404 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs78 ; rdf:predicate up:annotation ; rdf:object ?annotation79 . _:7405 a rdf:Statement ; up:attribution _:7353 ; rdf:subject ?pfs78 ; rdf:predicate up:annotation ; rdf:object ?annotation79 . _:7406 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs85 ; rdf:predicate up:annotation ; rdf:object ?annotation86 . _:7407 a rdf:Statement ; up:attribution _:7354 ; rdf:subject ?pfs85 ; rdf:predicate up:annotation ; rdf:object ?annotation86 . _:7408 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs92 ; rdf:predicate up:annotation ; rdf:object ?annotation93 . _:7409 a rdf:Statement ; up:attribution _:7355 ; rdf:subject ?pfs92 ; rdf:predicate up:annotation ; rdf:object ?annotation93 . _:7410 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs99 ; rdf:predicate up:annotation ; rdf:object ?annotation100 . _:7411 a rdf:Statement ; up:attribution _:7356 ; rdf:subject ?pfs99 ; rdf:predicate up:annotation ; rdf:object ?annotation100 . _:7412 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs106 ; rdf:predicate up:annotation ; rdf:object ?annotation107 . _:7413 a rdf:Statement ; up:attribution _:7357 ; rdf:subject ?pfs106 ; rdf:predicate up:annotation ; rdf:object ?annotation107 . _:7414 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs113 ; rdf:predicate up:annotation ; rdf:object ?annotation114 . _:7415 a rdf:Statement ; up:attribution _:7358 ; rdf:subject ?pfs113 ; rdf:predicate up:annotation ; rdf:object ?annotation114 . _:7416 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs120 ; rdf:predicate up:annotation ; rdf:object ?annotation121 . _:7417 a rdf:Statement ; up:attribution _:7359 ; rdf:subject ?pfs120 ; rdf:predicate up:annotation ; rdf:object ?annotation121 . _:7418 a rdf:Statement ; up:source unirule:MF_00016 ; rdf:subject ?pfs127 ; rdf:predicate up:annotation ; rdf:object ?annotation128 . _:7419 a rdf:Statement ; up:attribution _:7360 ; rdf:subject ?pfs127 ; rdf:predicate up:annotation ; rdf:object ?annotation128 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_00016 #Rule MF_00016 Created by:? on:2005-02-28 Modified by:Edouard de Castro on:2024-09-03 VALUES ?supertaxon134 {taxon:2 taxon:2191} ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_00016 . ?thisOrganism rdfs:subClassOf+ ?supertaxon134 . BIND(URI(CONCAT(STR(?this), '#MF_00016a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_00016a2')) AS ?annotation2) . BIND(URI(CONCAT(STR(?this), '#MF_00016a3')) AS ?annotation3) . BIND(URI(CONCAT(STR(?this), '#MF_00016a5')) AS ?annotation5) . BIND(URI(CONCAT(STR(?this), '#MF_00016a6')) AS ?annotation6) . BIND(URI(CONCAT(STR(?this), '#MF_00016a8')) AS ?annotation8) . BIND(URI(CONCAT(STR(?this), '#MF_00016a9')) AS ?annotation9) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch139 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1140 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1142 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016135 . ?templateMotifSequenceMatchRegionQ5M2B1140 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1141 . ?templateMotifSequenceMatchBeginQ5M2B1141 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1136 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1142 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch143 faldo:location ?targetMotifMatchRegionMatch144 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016146 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016137 . ?targetMotifMatchRegionMatch144 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016145 . ?targetMotifMatchRegionMatchBeginMF_00016145 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016138 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016146 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016135, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016135) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016135, CONCAT('^(?:-*[^-]){', STR(((1 - ?templateMotifSequenceMatchBeginPositionQ5M2B1136) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1147) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016137, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016137) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016137, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1147), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016137, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016137) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016137, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1147), '}'), '')))), '[^-]', ''))) AS ?step2148) . BIND(((?step2148 + ?targetMotifMatchRegionMatchBeginPositionMF_00016138) - 1) AS ?thisPositionOn15) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016135, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016135) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016135, CONCAT('^(?:-*[^-]){', STR(((181 - ?templateMotifSequenceMatchBeginPositionQ5M2B1136) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1149) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016137, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016137) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016137, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1149), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016137, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016137) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016137, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1149), '}'), '')))), '[^-]', ''))) AS ?step2150) . BIND(((?step2150 + ?targetMotifMatchRegionMatchBeginPositionMF_00016138) - 1) AS ?thisPositionOn16) . BIND(?this AS ?pfs1t151) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfsb13) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn16))) AS ?pfse14) . FILTER ((BOUND(?thisPositionOn15) && BOUND(?thisPositionOn16))) . BIND(URI(CONCAT(STR(?this), '#MF_00016a12')) AS ?annotation12) . BIND(?this AS ?pfs11) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch156 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1157 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1159 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016152 . ?templateMotifSequenceMatchRegionQ5M2B1157 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1158 . ?templateMotifSequenceMatchBeginQ5M2B1158 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1153 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1159 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch160 faldo:location ?targetMotifMatchRegionMatch161 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016163 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016154 . ?targetMotifMatchRegionMatch161 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016162 . ?targetMotifMatchRegionMatchBeginMF_00016162 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016155 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016163 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016152, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016152) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016152, CONCAT('^(?:-*[^-]){', STR(((182 - ?templateMotifSequenceMatchBeginPositionQ5M2B1153) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1164) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016154, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016154) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016154, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1164), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016154, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016154) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016154, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1164), '}'), '')))), '[^-]', ''))) AS ?step2165) . BIND(((?step2165 + ?targetMotifMatchRegionMatchBeginPositionMF_00016155) - 1) AS ?thisPositionOn21) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016152, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016152) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016152, CONCAT('^(?:-*[^-]){', STR(((252 - ?templateMotifSequenceMatchBeginPositionQ5M2B1153) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1166) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016154, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016154) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016154, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1166), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016154, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016154) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016154, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1166), '}'), '')))), '[^-]', ''))) AS ?step2167) . BIND(((?step2167 + ?targetMotifMatchRegionMatchBeginPositionMF_00016155) - 1) AS ?thisPositionOn22) . BIND(?this AS ?pfs1t168) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfsb19) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfse20) . FILTER ((BOUND(?thisPositionOn21) && BOUND(?thisPositionOn22))) . BIND(URI(CONCAT(STR(?this), '#MF_00016a18')) AS ?annotation18) . BIND(?this AS ?pfs17) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch173 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1174 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1176 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016169 . ?templateMotifSequenceMatchRegionQ5M2B1174 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1175 . ?templateMotifSequenceMatchBeginQ5M2B1175 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1170 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1176 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch177 faldo:location ?targetMotifMatchRegionMatch178 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016180 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016171 . ?targetMotifMatchRegionMatch178 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016179 . ?targetMotifMatchRegionMatchBeginMF_00016179 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016172 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016180 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016169, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016169) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016169, CONCAT('^(?:-*[^-]){', STR(((255 - ?templateMotifSequenceMatchBeginPositionQ5M2B1170) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1181) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016171, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016171) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016171, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1181), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016171, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016171) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016171, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1181), '}'), '')))), '[^-]', ''))) AS ?step2182) . BIND(((?step2182 + ?targetMotifMatchRegionMatchBeginPositionMF_00016172) - 1) AS ?thisPositionOn27) . BIND(STRLEN(?thisSequenceValue) AS ?thisPositionOn28) . BIND(?this AS ?pfs1t183) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn27))) AS ?pfsb25) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfse26) . FILTER ((BOUND(?thisPositionOn27) && BOUND(?thisPositionOn28))) . BIND(URI(CONCAT(STR(?this), '#MF_00016a24')) AS ?annotation24) . BIND(?this AS ?pfs23) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch188 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1189 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1191 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016184 . ?templateMotifSequenceMatchRegionQ5M2B1189 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1190 . ?templateMotifSequenceMatchBeginQ5M2B1190 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1185 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1191 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch192 faldo:location ?targetMotifMatchRegionMatch193 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016195 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016186 . ?targetMotifMatchRegionMatch193 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016194 . ?targetMotifMatchRegionMatchBeginMF_00016194 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016187 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016195 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016184, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016184) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016184, CONCAT('^(?:-*[^-]){', STR(((20 - ?templateMotifSequenceMatchBeginPositionQ5M2B1185) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1196) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016186, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016186) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016186, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1196), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016186, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016186) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016186, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1196), '}'), '')))), '[^-]', ''))) AS ?step2197) . BIND(((?step2197 + ?targetMotifMatchRegionMatchBeginPositionMF_00016187) - 1) AS ?thisPositionOn34) . BIND(?thisPositionOn34 AS ?thisPositionOn35) . BIND(?this AS ?pfs1t198) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn34))) AS ?pfsb31) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn35))) AS ?pfse32) . FILTER (REGEX('[LI]', SUBSTR(?thisSequenceValue, ?thisPositionOn34, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_00016a30')) AS ?annotation30) . BIND(?this AS ?pfs29) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch203 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1204 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1206 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016199 . ?templateMotifSequenceMatchRegionQ5M2B1204 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1205 . ?templateMotifSequenceMatchBeginQ5M2B1205 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1200 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1206 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch207 faldo:location ?targetMotifMatchRegionMatch208 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016210 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016201 . ?targetMotifMatchRegionMatch208 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016209 . ?targetMotifMatchRegionMatchBeginMF_00016209 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016202 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016210 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016199, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016199) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016199, CONCAT('^(?:-*[^-]){', STR(((21 - ?templateMotifSequenceMatchBeginPositionQ5M2B1200) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1211) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016201, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016201) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016201, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1211), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016201, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016201) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016201, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1211), '}'), '')))), '[^-]', ''))) AS ?step2212) . BIND(((?step2212 + ?targetMotifMatchRegionMatchBeginPositionMF_00016202) - 1) AS ?thisPositionOn41) . BIND(?thisPositionOn41 AS ?thisPositionOn42) . BIND(?this AS ?pfs1t213) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn41))) AS ?pfsb38) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn42))) AS ?pfse39) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn41, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a37')) AS ?annotation37) . BIND(?this AS ?pfs36) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch218 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1219 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1221 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016214 . ?templateMotifSequenceMatchRegionQ5M2B1219 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1220 . ?templateMotifSequenceMatchBeginQ5M2B1220 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1215 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1221 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch222 faldo:location ?targetMotifMatchRegionMatch223 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016225 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016216 . ?targetMotifMatchRegionMatch223 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016224 . ?targetMotifMatchRegionMatchBeginMF_00016224 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016217 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016225 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016214, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016214) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016214, CONCAT('^(?:-*[^-]){', STR(((62 - ?templateMotifSequenceMatchBeginPositionQ5M2B1215) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1226) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016216, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016216) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016216, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1226), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016216, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016216) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016216, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1226), '}'), '')))), '[^-]', ''))) AS ?step2227) . BIND(((?step2227 + ?targetMotifMatchRegionMatchBeginPositionMF_00016217) - 1) AS ?thisPositionOn48) . BIND(?thisPositionOn48 AS ?thisPositionOn49) . BIND(?this AS ?pfs1t228) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn48))) AS ?pfsb45) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn49))) AS ?pfse46) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn48, 1) = 'G')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a44')) AS ?annotation44) . BIND(?this AS ?pfs43) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch233 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1234 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1236 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016229 . ?templateMotifSequenceMatchRegionQ5M2B1234 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1235 . ?templateMotifSequenceMatchBeginQ5M2B1235 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1230 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1236 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch237 faldo:location ?targetMotifMatchRegionMatch238 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016240 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016231 . ?targetMotifMatchRegionMatch238 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016239 . ?targetMotifMatchRegionMatchBeginMF_00016239 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016232 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016240 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016229, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016229) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016229, CONCAT('^(?:-*[^-]){', STR(((65 - ?templateMotifSequenceMatchBeginPositionQ5M2B1230) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1241) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016231, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016231) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016231, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1241), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016231, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016231) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016231, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1241), '}'), '')))), '[^-]', ''))) AS ?step2242) . BIND(((?step2242 + ?targetMotifMatchRegionMatchBeginPositionMF_00016232) - 1) AS ?thisPositionOn55) . BIND(?thisPositionOn55 AS ?thisPositionOn56) . BIND(?this AS ?pfs1t243) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn55))) AS ?pfsb52) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn56))) AS ?pfse53) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn55, 1) = 'K')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a51')) AS ?annotation51) . BIND(?this AS ?pfs50) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch248 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1249 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1251 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016244 . ?templateMotifSequenceMatchRegionQ5M2B1249 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1250 . ?templateMotifSequenceMatchBeginQ5M2B1250 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1245 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1251 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch252 faldo:location ?targetMotifMatchRegionMatch253 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016255 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016246 . ?targetMotifMatchRegionMatch253 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016254 . ?targetMotifMatchRegionMatchBeginMF_00016254 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016247 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016255 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016244, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016244) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016244, CONCAT('^(?:-*[^-]){', STR(((66 - ?templateMotifSequenceMatchBeginPositionQ5M2B1245) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1256) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016246, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016246) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016246, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1256), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016246, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016246) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016246, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1256), '}'), '')))), '[^-]', ''))) AS ?step2257) . BIND(((?step2257 + ?targetMotifMatchRegionMatchBeginPositionMF_00016247) - 1) AS ?thisPositionOn62) . BIND(?thisPositionOn62 AS ?thisPositionOn63) . BIND(?this AS ?pfs1t258) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn62))) AS ?pfsb59) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn63))) AS ?pfse60) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn62, 1) = 'T')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a58')) AS ?annotation58) . BIND(?this AS ?pfs57) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch263 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1264 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1266 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016259 . ?templateMotifSequenceMatchRegionQ5M2B1264 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1265 . ?templateMotifSequenceMatchBeginQ5M2B1265 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1260 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1266 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch267 faldo:location ?targetMotifMatchRegionMatch268 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016270 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016261 . ?targetMotifMatchRegionMatch268 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016269 . ?targetMotifMatchRegionMatchBeginMF_00016269 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016262 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016270 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016259, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016259) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016259, CONCAT('^(?:-*[^-]){', STR(((66 - ?templateMotifSequenceMatchBeginPositionQ5M2B1260) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1271) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016261, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016261) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016261, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1271), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016261, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016261) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016261, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1271), '}'), '')))), '[^-]', ''))) AS ?step2272) . BIND(((?step2272 + ?targetMotifMatchRegionMatchBeginPositionMF_00016262) - 1) AS ?thisPositionOn69) . BIND(?thisPositionOn69 AS ?thisPositionOn70) . BIND(?this AS ?pfs1t273) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn69))) AS ?pfsb66) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn70))) AS ?pfse67) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn69, 1) = 'T')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a65')) AS ?annotation65) . BIND(?this AS ?pfs64) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch278 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1279 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1281 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016274 . ?templateMotifSequenceMatchRegionQ5M2B1279 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1280 . ?templateMotifSequenceMatchBeginQ5M2B1280 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1275 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1281 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch282 faldo:location ?targetMotifMatchRegionMatch283 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016285 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016276 . ?targetMotifMatchRegionMatch283 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016284 . ?targetMotifMatchRegionMatchBeginMF_00016284 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016277 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016285 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016274, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016274) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016274, CONCAT('^(?:-*[^-]){', STR(((67 - ?templateMotifSequenceMatchBeginPositionQ5M2B1275) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1286) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016276, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016276) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016276, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1286), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016276, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016276) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016276, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1286), '}'), '')))), '[^-]', ''))) AS ?step2287) . BIND(((?step2287 + ?targetMotifMatchRegionMatchBeginPositionMF_00016277) - 1) AS ?thisPositionOn76) . BIND(?thisPositionOn76 AS ?thisPositionOn77) . BIND(?this AS ?pfs1t288) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn76))) AS ?pfsb73) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn77))) AS ?pfse74) . FILTER (REGEX('[TS]', SUBSTR(?thisSequenceValue, ?thisPositionOn76, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_00016a72')) AS ?annotation72) . BIND(?this AS ?pfs71) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch293 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1294 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1296 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016289 . ?templateMotifSequenceMatchRegionQ5M2B1294 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1295 . ?templateMotifSequenceMatchBeginQ5M2B1295 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1290 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1296 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch297 faldo:location ?targetMotifMatchRegionMatch298 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016300 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016291 . ?targetMotifMatchRegionMatch298 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016299 . ?targetMotifMatchRegionMatchBeginMF_00016299 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016292 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016300 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016289, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016289) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016289, CONCAT('^(?:-*[^-]){', STR(((128 - ?templateMotifSequenceMatchBeginPositionQ5M2B1290) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1301) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016291, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016291) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016291, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1301), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016291, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016291) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016291, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1301), '}'), '')))), '[^-]', ''))) AS ?step2302) . BIND(((?step2302 + ?targetMotifMatchRegionMatchBeginPositionMF_00016292) - 1) AS ?thisPositionOn83) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016289, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016289) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016289, CONCAT('^(?:-*[^-]){', STR(((130 - ?templateMotifSequenceMatchBeginPositionQ5M2B1290) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1303) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016291, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016291) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016291, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1303), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016291, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016291) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016291, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1303), '}'), '')))), '[^-]', ''))) AS ?step2304) . BIND(((?step2304 + ?targetMotifMatchRegionMatchBeginPositionMF_00016292) - 1) AS ?thisPositionOn84) . BIND(?this AS ?pfs1t305) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn83))) AS ?pfsb80) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn84))) AS ?pfse81) . FILTER (REGEX('[ED]D[YF]', SUBSTR(?thisSequenceValue, ?thisPositionOn83, (?thisPositionOn84 - ?thisPositionOn83)))) . BIND(URI(CONCAT(STR(?this), '#MF_00016a79')) AS ?annotation79) . BIND(?this AS ?pfs78) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch310 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1311 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1313 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016306 . ?templateMotifSequenceMatchRegionQ5M2B1311 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1312 . ?templateMotifSequenceMatchBeginQ5M2B1312 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1307 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1313 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch314 faldo:location ?targetMotifMatchRegionMatch315 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016317 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016308 . ?targetMotifMatchRegionMatch315 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016316 . ?targetMotifMatchRegionMatchBeginMF_00016316 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016309 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016317 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016306, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016306) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016306, CONCAT('^(?:-*[^-]){', STR(((171 - ?templateMotifSequenceMatchBeginPositionQ5M2B1307) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1318) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016308, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016308) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016308, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1318), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016308, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016308) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016308, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1318), '}'), '')))), '[^-]', ''))) AS ?step2319) . BIND(((?step2319 + ?targetMotifMatchRegionMatchBeginPositionMF_00016309) - 1) AS ?thisPositionOn90) . BIND(?thisPositionOn90 AS ?thisPositionOn91) . BIND(?this AS ?pfs1t320) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn90))) AS ?pfsb87) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn91))) AS ?pfse88) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn90, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a86')) AS ?annotation86) . BIND(?this AS ?pfs85) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch325 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1326 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1328 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016321 . ?templateMotifSequenceMatchRegionQ5M2B1326 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1327 . ?templateMotifSequenceMatchBeginQ5M2B1327 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1322 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1328 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch329 faldo:location ?targetMotifMatchRegionMatch330 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016332 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016323 . ?targetMotifMatchRegionMatch330 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016331 . ?targetMotifMatchRegionMatchBeginMF_00016331 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016324 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016332 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016321, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016321) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016321, CONCAT('^(?:-*[^-]){', STR(((181 - ?templateMotifSequenceMatchBeginPositionQ5M2B1322) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1333) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016323, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016323) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016323, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1333), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016323, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016323) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016323, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1333), '}'), '')))), '[^-]', ''))) AS ?step2334) . BIND(((?step2334 + ?targetMotifMatchRegionMatchBeginPositionMF_00016324) - 1) AS ?thisPositionOn97) . BIND(?thisPositionOn97 AS ?thisPositionOn98) . BIND(?this AS ?pfs1t335) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn97))) AS ?pfsb94) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn98))) AS ?pfse95) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn97, 1) = 'Y')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a93')) AS ?annotation93) . BIND(?this AS ?pfs92) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch340 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1341 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1343 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016336 . ?templateMotifSequenceMatchRegionQ5M2B1341 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1342 . ?templateMotifSequenceMatchBeginQ5M2B1342 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1337 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1343 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch344 faldo:location ?targetMotifMatchRegionMatch345 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016347 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016338 . ?targetMotifMatchRegionMatch345 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016346 . ?targetMotifMatchRegionMatchBeginMF_00016346 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016339 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016347 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016336, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016336) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016336, CONCAT('^(?:-*[^-]){', STR(((218 - ?templateMotifSequenceMatchBeginPositionQ5M2B1337) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1348) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016338, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016338) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016338, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1348), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016338, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016338) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016338, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1348), '}'), '')))), '[^-]', ''))) AS ?step2349) . BIND(((?step2349 + ?targetMotifMatchRegionMatchBeginPositionMF_00016339) - 1) AS ?thisPositionOn104) . BIND(?thisPositionOn104 AS ?thisPositionOn105) . BIND(?this AS ?pfs1t350) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn104))) AS ?pfsb101) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn105))) AS ?pfse102) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn104, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a100')) AS ?annotation100) . BIND(?this AS ?pfs99) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch355 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1356 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1358 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016351 . ?templateMotifSequenceMatchRegionQ5M2B1356 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1357 . ?templateMotifSequenceMatchBeginQ5M2B1357 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1352 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1358 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch359 faldo:location ?targetMotifMatchRegionMatch360 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016362 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016353 . ?targetMotifMatchRegionMatch360 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016361 . ?targetMotifMatchRegionMatchBeginMF_00016361 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016354 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016362 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016351, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016351) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016351, CONCAT('^(?:-*[^-]){', STR(((291 - ?templateMotifSequenceMatchBeginPositionQ5M2B1352) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1363) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016353, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016353) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016353, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1363), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016353, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016353) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016353, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1363), '}'), '')))), '[^-]', ''))) AS ?step2364) . BIND(((?step2364 + ?targetMotifMatchRegionMatchBeginPositionMF_00016354) - 1) AS ?thisPositionOn111) . BIND(?thisPositionOn111 AS ?thisPositionOn112) . BIND(?this AS ?pfs1t365) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn111))) AS ?pfsb108) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn112))) AS ?pfse109) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn111, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a107')) AS ?annotation107) . BIND(?this AS ?pfs106) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch370 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1371 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1373 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016366 . ?templateMotifSequenceMatchRegionQ5M2B1371 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1372 . ?templateMotifSequenceMatchBeginQ5M2B1372 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1367 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1373 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch374 faldo:location ?targetMotifMatchRegionMatch375 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016377 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016368 . ?targetMotifMatchRegionMatch375 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016376 . ?targetMotifMatchRegionMatchBeginMF_00016376 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016369 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016377 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016366, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016366) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016366, CONCAT('^(?:-*[^-]){', STR(((310 - ?templateMotifSequenceMatchBeginPositionQ5M2B1367) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1378) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016368, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016368) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016368, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1378), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016368, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016368) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016368, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1378), '}'), '')))), '[^-]', ''))) AS ?step2379) . BIND(((?step2379 + ?targetMotifMatchRegionMatchBeginPositionMF_00016369) - 1) AS ?thisPositionOn118) . BIND(?thisPositionOn118 AS ?thisPositionOn119) . BIND(?this AS ?pfs1t380) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn118))) AS ?pfsb115) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn119))) AS ?pfse116) . FILTER (REGEX('[RK]', SUBSTR(?thisSequenceValue, ?thisPositionOn118, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_00016a114')) AS ?annotation114) . BIND(?this AS ?pfs113) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch385 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1386 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1388 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016381 . ?templateMotifSequenceMatchRegionQ5M2B1386 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1387 . ?templateMotifSequenceMatchBeginQ5M2B1387 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1382 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1388 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch389 faldo:location ?targetMotifMatchRegionMatch390 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016392 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016383 . ?targetMotifMatchRegionMatch390 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016391 . ?targetMotifMatchRegionMatchBeginMF_00016391 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016384 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016392 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016381, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016381) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016381, CONCAT('^(?:-*[^-]){', STR(((312 - ?templateMotifSequenceMatchBeginPositionQ5M2B1382) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1393) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016383, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016383) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016383, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1393), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016383, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016383) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016383, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1393), '}'), '')))), '[^-]', ''))) AS ?step2394) . BIND(((?step2394 + ?targetMotifMatchRegionMatchBeginPositionMF_00016384) - 1) AS ?thisPositionOn125) . BIND(?thisPositionOn125 AS ?thisPositionOn126) . BIND(?this AS ?pfs1t395) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn125))) AS ?pfsb122) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn126))) AS ?pfse123) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn125, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a121')) AS ?annotation121) . BIND(?this AS ?pfs120) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch400 faldo:location ?templateMotifSequenceMatchRegionQ5M2B1401 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5M2B1403 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ5M2B1MF_00016396 . ?templateMotifSequenceMatchRegionQ5M2B1401 faldo:begin ?templateMotifSequenceMatchBeginQ5M2B1402 . ?templateMotifSequenceMatchBeginQ5M2B1402 faldo:position ?templateMotifSequenceMatchBeginPositionQ5M2B1397 ; faldo:reference isoform:Q5M2B1-1 . ?templateMotifSequenceProfileAlignmentOperationQ5M2B1403 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . ?targetMotifMatch404 faldo:location ?targetMotifMatchRegionMatch405 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00016407 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ5M2B1MF_00016398 . ?targetMotifMatchRegionMatch405 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00016406 . ?targetMotifMatchRegionMatchBeginMF_00016406 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00016399 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00016407 edam:has_input signature:MF_00016 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ5M2B1MF_00016396, 1, (STRLEN(?templateMotifCigarQ5M2B1MF_00016396) - STRLEN(REPLACE(?templateMotifCigarQ5M2B1MF_00016396, CONCAT('^(?:-*[^-]){', STR(((315 - ?templateMotifSequenceMatchBeginPositionQ5M2B1397) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1408) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016398, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016398) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016398, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1408), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ5M2B1MF_00016398, 1, (STRLEN(?targetMotifMatchCigarQ5M2B1MF_00016398) - STRLEN(REPLACE(?targetMotifMatchCigarQ5M2B1MF_00016398, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1408), '}'), '')))), '[^-]', ''))) AS ?step2409) . BIND(((?step2409 + ?targetMotifMatchRegionMatchBeginPositionMF_00016399) - 1) AS ?thisPositionOn132) . BIND(?thisPositionOn132 AS ?thisPositionOn133) . BIND(?this AS ?pfs1t410) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn132))) AS ?pfsb129) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn133))) AS ?pfse130) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn132, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_00016a128')) AS ?annotation128) . BIND(?this AS ?pfs127) . } OPTIONAL { ?this a up:Protein . ?this up:organism ?thisOrganism . ?thisOrganism rdfs:subClassOf+ taxon:561 . BIND(?this AS ?case10) . } }