CONSTRUCT { _:72081 up:source unirule:MF_00181 . _:72082 up:source unirule:MF_00181 . _:72083 up:source unirule:MF_00181 . _:72084 up:source unirule:MF_00181 . _:72085 up:source unirule:MF_00181 . _:72086 up:source unirule:MF_00181 . _:72087 up:source unirule:MF_00181 . _:72088 up:source unirule:MF_00181 . _:72089 up:source unirule:MF_00181 . _:72090 up:source unirule:MF_00181 . _:72091 up:source unirule:MF_00181 . _:72092 up:source unirule:MF_00181 . _:72093 up:source unirule:MF_00181 . _:72094 up:source unirule:MF_00181 . _:72095 up:source unirule:MF_00181 . _:72096 up:source unirule:MF_00181 . _:72097 up:source unirule:MF_00181 . _:72098 up:source unirule:MF_00181 . _:72099 up:source unirule:MF_00181 . _:72100 up:source unirule:MF_00181 . _:72101 up:source unirule:MF_00181 . _:72102 up:source unirule:MF_00181 . _:72103 up:source unirule:MF_00181 . _:72104 up:source unirule:MF_00181 . _:72105 up:source unirule:MF_00181 . _:72106 up:source unirule:MF_00181 . _:72107 up:source unirule:MF_00181 . _:72108 up:source unirule:MF_00181 . _:72109 up:source unirule:MF_00181 . ?this up:alternativeName ?name1 , ?name2 ; up:annotation ?annotation4 , ?annotation5 , ?annotation7 , ?annotation9 , ?annotation10 , ?annotation12 ; up:classifiedWith GO:0004177 , GO:0005737 , GO:0008235 , GO:0030145 , keyword:31 , keyword:378 , keyword:464 , keyword:479 , keyword:645 , keyword:963 ; up:recommendedName ?name0 . ?name0 up:ecName '3.4.11.1' ; up:fullName 'Probable cytosol aminopeptidase' ; rdf:type up:Structured_Name . ?name1 up:ecName '3.4.11.10' ; up:fullName 'Leucine aminopeptidase' ; up:shortName 'LAP' ; rdf:type up:Structured_Name . ?name2 up:fullName 'Leucyl aminopeptidase' ; rdf:type up:Structured_Name . ?gene3 skos:prefLabel 'pepA' . ?annotation4 a up:Function_Annotation ; rdfs:comment 'Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.' . ?annotation5 up:activity ?activity6 ; rdf:type up:Catalytic_Activity_Annotation . ?activity6 up:enzymeClass <http://purl.uniprot.org/enzyme/3.4.11.1>. ?annotation7 up:activity ?activity8 ; rdf:type up:Catalytic_Activity_Annotation . ?activity8 up:enzymeClass <http://purl.uniprot.org/enzyme/3.4.11.10>. ?annotation9 up:cofactor chebi:29035 ; rdf:type up:Cofactor_Annotation ; rdfs:comment 'Binds 2 manganese ions per subunit.' . ?annotation10 a up:Subcellular_Location_Annotation . ?annotation10li11 up:cellularComponent <http://purl.uniprot.org/locations/null>. ?annotation12 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the peptidase M17 family.' . ?pfs13 up:annotation ?annotation14 . ?annotation14 faldo:begin ?pfsb15 ; faldo:end ?pfse16 ; rdf:type up:Active_Site_Annotation . ?pfsb15 faldo:position ?thisPositionOn17 ; rdf:type faldo:ExactPosition . ?pfse16 faldo:position ?thisPositionOn18 ; rdf:type faldo:ExactPosition . ?pfs19 up:annotation ?annotation20 . ?annotation20 faldo:begin ?pfsb21 ; faldo:end ?pfse22 ; rdf:type up:Active_Site_Annotation . ?pfsb21 faldo:position ?thisPositionOn23 ; rdf:type faldo:ExactPosition . ?pfse22 faldo:position ?thisPositionOn24 ; rdf:type faldo:ExactPosition . ?pfs25 up:annotation ?annotation26 . ?annotation26 faldo:begin ?pfsb27 ; faldo:end ?pfse28 ; up:ligand ?ligand29 ; rdf:type up:Binding_Site_Annotation . ?pfsb27 faldo:position ?thisPositionOn30 ; rdf:type faldo:ExactPosition . ?pfse28 faldo:position ?thisPositionOn31 ; rdf:type faldo:ExactPosition . ?ligand29 rdfs:subClassOf chebi:29035 . ?pfs32 up:annotation ?annotation33 . ?annotation33 faldo:begin ?pfsb34 ; faldo:end ?pfse35 ; up:ligand ?ligand36 ; rdf:type up:Binding_Site_Annotation . ?pfsb34 faldo:position ?thisPositionOn37 ; rdf:type faldo:ExactPosition . ?pfse35 faldo:position ?thisPositionOn38 ; rdf:type faldo:ExactPosition . ?ligand36 rdfs:subClassOf chebi:29035 . ?pfs39 up:annotation ?annotation40 . ?annotation40 faldo:begin ?pfsb41 ; faldo:end ?pfse42 ; up:ligand ?ligand43 ; rdf:type up:Binding_Site_Annotation . ?pfsb41 faldo:position ?thisPositionOn44 ; rdf:type faldo:ExactPosition . ?pfse42 faldo:position ?thisPositionOn45 ; rdf:type faldo:ExactPosition . ?ligand43 rdfs:subClassOf chebi:29035 . ?pfs46 up:annotation ?annotation47 . ?annotation47 faldo:begin ?pfsb48 ; faldo:end ?pfse49 ; up:ligand ?ligand50 ; rdf:type up:Binding_Site_Annotation . ?pfsb48 faldo:position ?thisPositionOn51 ; rdf:type faldo:ExactPosition . ?pfse49 faldo:position ?thisPositionOn52 ; rdf:type faldo:ExactPosition . ?ligand50 rdfs:subClassOf chebi:29035 . ?pfs53 up:annotation ?annotation54 . ?annotation54 faldo:begin ?pfsb55 ; faldo:end ?pfse56 ; up:ligand ?ligand57 ; rdf:type up:Binding_Site_Annotation . ?pfsb55 faldo:position ?thisPositionOn58 ; rdf:type faldo:ExactPosition . ?pfse56 faldo:position ?thisPositionOn59 ; rdf:type faldo:ExactPosition . ?ligand57 rdfs:subClassOf chebi:29035 . ?pfs60 up:annotation ?annotation61 . ?annotation61 faldo:begin ?pfsb62 ; faldo:end ?pfse63 ; up:ligand ?ligand64 ; rdf:type up:Binding_Site_Annotation . ?pfsb62 faldo:position ?thisPositionOn65 ; rdf:type faldo:ExactPosition . ?pfse63 faldo:position ?thisPositionOn66 ; rdf:type faldo:ExactPosition . ?ligand64 rdfs:subClassOf chebi:29035 . ?pfs67 up:annotation ?annotation68 . ?annotation68 faldo:begin ?pfsb69 ; faldo:end ?pfse70 ; up:ligand ?ligand71 ; rdf:type up:Binding_Site_Annotation . ?pfsb69 faldo:position ?thisPositionOn72 ; rdf:type faldo:ExactPosition . ?pfse70 faldo:position ?thisPositionOn73 ; rdf:type faldo:ExactPosition . ?ligand71 rdfs:subClassOf chebi:29035 . _:72110 a rdf:Statement ; up:attribution _:72081 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:72111 a rdf:Statement ; up:attribution _:72082 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name1 . _:72112 a rdf:Statement ; up:attribution _:72083 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name2 . _:72113 a rdf:Statement ; up:attribution _:72084 ; rdf:subject ?gene3 ; rdf:predicate up:encodedBy ; rdf:object ?gene3 . _:72114 a rdf:Statement ; up:attribution _:72085 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation4 . _:72115 a rdf:Statement ; up:attribution _:72086 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation5 . _:72116 a rdf:Statement ; up:attribution _:72087 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation7 . _:72117 a rdf:Statement ; up:attribution _:72088 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation9 . _:72118 a rdf:Statement ; up:attribution _:72089 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation10 . _:72119 a rdf:Statement ; up:attribution _:72090 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:72120 a rdf:Statement ; up:attribution _:72091 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:963 . _:72121 a rdf:Statement ; up:attribution _:72092 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:378 . _:72122 a rdf:Statement ; up:attribution _:72093 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:645 . _:72123 a rdf:Statement ; up:attribution _:72094 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:31 . _:72124 a rdf:Statement ; up:attribution _:72095 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:464 . _:72125 a rdf:Statement ; up:attribution _:72096 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:479 . _:72126 a rdf:Statement ; up:attribution _:72097 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0004177 . _:72127 a rdf:Statement ; up:attribution _:72098 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0008235 . _:72128 a rdf:Statement ; up:attribution _:72099 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0030145 . _:72129 a rdf:Statement ; up:attribution _:72100 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0005737 . _:72130 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs13 ; rdf:predicate up:annotation ; rdf:object ?annotation14 . _:72131 a rdf:Statement ; up:attribution _:72101 ; rdf:subject ?pfs13 ; rdf:predicate up:annotation ; rdf:object ?annotation14 . _:72132 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs19 ; rdf:predicate up:annotation ; rdf:object ?annotation20 . _:72133 a rdf:Statement ; up:attribution _:72102 ; rdf:subject ?pfs19 ; rdf:predicate up:annotation ; rdf:object ?annotation20 . _:72134 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs25 ; rdf:predicate up:annotation ; rdf:object ?annotation26 . _:72135 a rdf:Statement ; up:attribution _:72103 ; rdf:subject ?pfs25 ; rdf:predicate up:annotation ; rdf:object ?annotation26 . _:72136 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs32 ; rdf:predicate up:annotation ; rdf:object ?annotation33 . _:72137 a rdf:Statement ; up:attribution _:72104 ; rdf:subject ?pfs32 ; rdf:predicate up:annotation ; rdf:object ?annotation33 . _:72138 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs39 ; rdf:predicate up:annotation ; rdf:object ?annotation40 . _:72139 a rdf:Statement ; up:attribution _:72105 ; rdf:subject ?pfs39 ; rdf:predicate up:annotation ; rdf:object ?annotation40 . _:72140 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs46 ; rdf:predicate up:annotation ; rdf:object ?annotation47 . _:72141 a rdf:Statement ; up:attribution _:72106 ; rdf:subject ?pfs46 ; rdf:predicate up:annotation ; rdf:object ?annotation47 . _:72142 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs53 ; rdf:predicate up:annotation ; rdf:object ?annotation54 . _:72143 a rdf:Statement ; up:attribution _:72107 ; rdf:subject ?pfs53 ; rdf:predicate up:annotation ; rdf:object ?annotation54 . _:72144 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs60 ; rdf:predicate up:annotation ; rdf:object ?annotation61 . _:72145 a rdf:Statement ; up:attribution _:72108 ; rdf:subject ?pfs60 ; rdf:predicate up:annotation ; rdf:object ?annotation61 . _:72146 a rdf:Statement ; up:source unirule:MF_00181 ; rdf:subject ?pfs67 ; rdf:predicate up:annotation ; rdf:object ?annotation68 . _:72147 a rdf:Statement ; up:attribution _:72109 ; rdf:subject ?pfs67 ; rdf:predicate up:annotation ; rdf:object ?annotation68 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_00181 #Rule MF_00181 Created by:hamap on:2001-06-01 Modified by:crivoire on:2023-01-17 VALUES ?supertaxon74 {taxon:2 taxon:2157} ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_00181 . ?thisOrganism rdfs:subClassOf+ ?supertaxon74 . BIND(URI(CONCAT(STR(?this), '#MF_00181a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_00181a1')) AS ?name1) . BIND(URI(CONCAT(STR(?this), '#MF_00181a2')) AS ?name2) . BIND(URI(CONCAT(STR(?this), '#MF_00181a4')) AS ?annotation4) . BIND(URI(CONCAT(STR(?this), '#MF_00181a5')) AS ?annotation5) . BIND(URI(CONCAT(STR(?this), '#MF_00181a7')) AS ?annotation7) . BIND(URI(CONCAT(STR(?this), '#MF_00181a9')) AS ?annotation9) . BIND(URI(CONCAT(STR(?this), '#MF_00181a10')) AS ?annotation10) . BIND(URI(CONCAT(STR(?this), '#MF_00181a12')) AS ?annotation12) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch79 faldo:location ?templateMotifSequenceMatchRegionP6876780 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP6876782 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_0018175 . ?templateMotifSequenceMatchRegionP6876780 faldo:begin ?templateMotifSequenceMatchBeginP6876781 . ?templateMotifSequenceMatchBeginP6876781 faldo:position ?templateMotifSequenceMatchBeginPositionP6876776 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP6876782 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch83 faldo:location ?targetMotifMatchRegionMatch84 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0018186 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_0018177 . ?targetMotifMatchRegionMatch84 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0018185 . ?targetMotifMatchRegionMatchBeginMF_0018185 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0018178 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0018186 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_0018175, 1, (STRLEN(?templateMotifCigarP68767MF_0018175) - STRLEN(REPLACE(?templateMotifCigarP68767MF_0018175, CONCAT('^(?:-*[^-]){', STR(((282 - ?templateMotifSequenceMatchBeginPositionP6876776) + 1)), '}'), '')))), '[a-z]', '')) AS ?step187) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_0018177, 1, (STRLEN(?targetMotifMatchCigarP68767MF_0018177) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_0018177, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step187), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_0018177, 1, (STRLEN(?targetMotifMatchCigarP68767MF_0018177) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_0018177, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step187), '}'), '')))), '[^-]', ''))) AS ?step288) . BIND(((?step288 + ?targetMotifMatchRegionMatchBeginPositionMF_0018178) - 1) AS ?thisPositionOn17) . BIND(?thisPositionOn17 AS ?thisPositionOn18) . BIND(?this AS ?pfs1t89) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn17))) AS ?pfsb15) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn18))) AS ?pfse16) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn17, 1) = 'K')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a14')) AS ?annotation14) . BIND(?this AS ?pfs13) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch94 faldo:location ?templateMotifSequenceMatchRegionP6876795 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP6876797 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_0018190 . ?templateMotifSequenceMatchRegionP6876795 faldo:begin ?templateMotifSequenceMatchBeginP6876796 . ?templateMotifSequenceMatchBeginP6876796 faldo:position ?templateMotifSequenceMatchBeginPositionP6876791 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP6876797 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch98 faldo:location ?targetMotifMatchRegionMatch99 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00181101 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_0018192 . ?targetMotifMatchRegionMatch99 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00181100 . ?targetMotifMatchRegionMatchBeginMF_00181100 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0018193 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00181101 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_0018190, 1, (STRLEN(?templateMotifCigarP68767MF_0018190) - STRLEN(REPLACE(?templateMotifCigarP68767MF_0018190, CONCAT('^(?:-*[^-]){', STR(((356 - ?templateMotifSequenceMatchBeginPositionP6876791) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1102) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_0018192, 1, (STRLEN(?targetMotifMatchCigarP68767MF_0018192) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_0018192, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1102), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_0018192, 1, (STRLEN(?targetMotifMatchCigarP68767MF_0018192) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_0018192, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1102), '}'), '')))), '[^-]', ''))) AS ?step2103) . BIND(((?step2103 + ?targetMotifMatchRegionMatchBeginPositionMF_0018193) - 1) AS ?thisPositionOn23) . BIND(?thisPositionOn23 AS ?thisPositionOn24) . BIND(?this AS ?pfs1t104) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn23))) AS ?pfsb21) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn24))) AS ?pfse22) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn23, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a20')) AS ?annotation20) . BIND(?this AS ?pfs19) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch109 faldo:location ?templateMotifSequenceMatchRegionP68767110 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP68767112 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_00181105 . ?templateMotifSequenceMatchRegionP68767110 faldo:begin ?templateMotifSequenceMatchBeginP68767111 . ?templateMotifSequenceMatchBeginP68767111 faldo:position ?templateMotifSequenceMatchBeginPositionP68767106 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP68767112 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch113 faldo:location ?targetMotifMatchRegionMatch114 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00181116 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_00181107 . ?targetMotifMatchRegionMatch114 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00181115 . ?targetMotifMatchRegionMatchBeginMF_00181115 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00181108 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00181116 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_00181105, 1, (STRLEN(?templateMotifCigarP68767MF_00181105) - STRLEN(REPLACE(?templateMotifCigarP68767MF_00181105, CONCAT('^(?:-*[^-]){', STR(((270 - ?templateMotifSequenceMatchBeginPositionP68767106) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1117) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_00181107, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181107) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181107, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1117), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_00181107, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181107) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181107, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1117), '}'), '')))), '[^-]', ''))) AS ?step2118) . BIND(((?step2118 + ?targetMotifMatchRegionMatchBeginPositionMF_00181108) - 1) AS ?thisPositionOn30) . BIND(?thisPositionOn30 AS ?thisPositionOn31) . BIND(?this AS ?pfs1t119) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn30))) AS ?pfsb27) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn31))) AS ?pfse28) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn30, 1) = 'K')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a26')) AS ?annotation26) . BIND(?this AS ?pfs25) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch124 faldo:location ?templateMotifSequenceMatchRegionP68767125 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP68767127 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_00181120 . ?templateMotifSequenceMatchRegionP68767125 faldo:begin ?templateMotifSequenceMatchBeginP68767126 . ?templateMotifSequenceMatchBeginP68767126 faldo:position ?templateMotifSequenceMatchBeginPositionP68767121 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP68767127 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch128 faldo:location ?targetMotifMatchRegionMatch129 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00181131 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_00181122 . ?targetMotifMatchRegionMatch129 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00181130 . ?targetMotifMatchRegionMatchBeginMF_00181130 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00181123 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00181131 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_00181120, 1, (STRLEN(?templateMotifCigarP68767MF_00181120) - STRLEN(REPLACE(?templateMotifCigarP68767MF_00181120, CONCAT('^(?:-*[^-]){', STR(((275 - ?templateMotifSequenceMatchBeginPositionP68767121) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1132) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_00181122, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181122) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181122, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1132), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_00181122, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181122) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181122, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1132), '}'), '')))), '[^-]', ''))) AS ?step2133) . BIND(((?step2133 + ?targetMotifMatchRegionMatchBeginPositionMF_00181123) - 1) AS ?thisPositionOn37) . BIND(?thisPositionOn37 AS ?thisPositionOn38) . BIND(?this AS ?pfs1t134) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn37))) AS ?pfsb34) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn38))) AS ?pfse35) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn37, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a33')) AS ?annotation33) . BIND(?this AS ?pfs32) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch139 faldo:location ?templateMotifSequenceMatchRegionP68767140 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP68767142 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_00181135 . ?templateMotifSequenceMatchRegionP68767140 faldo:begin ?templateMotifSequenceMatchBeginP68767141 . ?templateMotifSequenceMatchBeginP68767141 faldo:position ?templateMotifSequenceMatchBeginPositionP68767136 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP68767142 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch143 faldo:location ?targetMotifMatchRegionMatch144 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00181146 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_00181137 . ?targetMotifMatchRegionMatch144 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00181145 . ?targetMotifMatchRegionMatchBeginMF_00181145 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00181138 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00181146 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_00181135, 1, (STRLEN(?templateMotifCigarP68767MF_00181135) - STRLEN(REPLACE(?templateMotifCigarP68767MF_00181135, CONCAT('^(?:-*[^-]){', STR(((275 - ?templateMotifSequenceMatchBeginPositionP68767136) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1147) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_00181137, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181137) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181137, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1147), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_00181137, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181137) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181137, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1147), '}'), '')))), '[^-]', ''))) AS ?step2148) . BIND(((?step2148 + ?targetMotifMatchRegionMatchBeginPositionMF_00181138) - 1) AS ?thisPositionOn44) . BIND(?thisPositionOn44 AS ?thisPositionOn45) . BIND(?this AS ?pfs1t149) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn44))) AS ?pfsb41) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn45))) AS ?pfse42) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn44, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a40')) AS ?annotation40) . BIND(?this AS ?pfs39) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch154 faldo:location ?templateMotifSequenceMatchRegionP68767155 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP68767157 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_00181150 . ?templateMotifSequenceMatchRegionP68767155 faldo:begin ?templateMotifSequenceMatchBeginP68767156 . ?templateMotifSequenceMatchBeginP68767156 faldo:position ?templateMotifSequenceMatchBeginPositionP68767151 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP68767157 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch158 faldo:location ?targetMotifMatchRegionMatch159 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00181161 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_00181152 . ?targetMotifMatchRegionMatch159 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00181160 . ?targetMotifMatchRegionMatchBeginMF_00181160 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00181153 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00181161 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_00181150, 1, (STRLEN(?templateMotifCigarP68767MF_00181150) - STRLEN(REPLACE(?templateMotifCigarP68767MF_00181150, CONCAT('^(?:-*[^-]){', STR(((293 - ?templateMotifSequenceMatchBeginPositionP68767151) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1162) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_00181152, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181152) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181152, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1162), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_00181152, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181152) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181152, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1162), '}'), '')))), '[^-]', ''))) AS ?step2163) . BIND(((?step2163 + ?targetMotifMatchRegionMatchBeginPositionMF_00181153) - 1) AS ?thisPositionOn51) . BIND(?thisPositionOn51 AS ?thisPositionOn52) . BIND(?this AS ?pfs1t164) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn51))) AS ?pfsb48) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn52))) AS ?pfse49) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn51, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a47')) AS ?annotation47) . BIND(?this AS ?pfs46) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch169 faldo:location ?templateMotifSequenceMatchRegionP68767170 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP68767172 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_00181165 . ?templateMotifSequenceMatchRegionP68767170 faldo:begin ?templateMotifSequenceMatchBeginP68767171 . ?templateMotifSequenceMatchBeginP68767171 faldo:position ?templateMotifSequenceMatchBeginPositionP68767166 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP68767172 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch173 faldo:location ?targetMotifMatchRegionMatch174 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00181176 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_00181167 . ?targetMotifMatchRegionMatch174 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00181175 . ?targetMotifMatchRegionMatchBeginMF_00181175 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00181168 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00181176 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_00181165, 1, (STRLEN(?templateMotifCigarP68767MF_00181165) - STRLEN(REPLACE(?templateMotifCigarP68767MF_00181165, CONCAT('^(?:-*[^-]){', STR(((352 - ?templateMotifSequenceMatchBeginPositionP68767166) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1177) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_00181167, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181167) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181167, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1177), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_00181167, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181167) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181167, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1177), '}'), '')))), '[^-]', ''))) AS ?step2178) . BIND(((?step2178 + ?targetMotifMatchRegionMatchBeginPositionMF_00181168) - 1) AS ?thisPositionOn58) . BIND(?thisPositionOn58 AS ?thisPositionOn59) . BIND(?this AS ?pfs1t179) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn58))) AS ?pfsb55) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn59))) AS ?pfse56) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn58, 1) = 'D')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a54')) AS ?annotation54) . BIND(?this AS ?pfs53) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch184 faldo:location ?templateMotifSequenceMatchRegionP68767185 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP68767187 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_00181180 . ?templateMotifSequenceMatchRegionP68767185 faldo:begin ?templateMotifSequenceMatchBeginP68767186 . ?templateMotifSequenceMatchBeginP68767186 faldo:position ?templateMotifSequenceMatchBeginPositionP68767181 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP68767187 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch188 faldo:location ?targetMotifMatchRegionMatch189 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00181191 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_00181182 . ?targetMotifMatchRegionMatch189 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00181190 . ?targetMotifMatchRegionMatchBeginMF_00181190 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00181183 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00181191 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_00181180, 1, (STRLEN(?templateMotifCigarP68767MF_00181180) - STRLEN(REPLACE(?templateMotifCigarP68767MF_00181180, CONCAT('^(?:-*[^-]){', STR(((354 - ?templateMotifSequenceMatchBeginPositionP68767181) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1192) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_00181182, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181182) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181182, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1192), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_00181182, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181182) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181182, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1192), '}'), '')))), '[^-]', ''))) AS ?step2193) . BIND(((?step2193 + ?targetMotifMatchRegionMatchBeginPositionMF_00181183) - 1) AS ?thisPositionOn65) . BIND(?thisPositionOn65 AS ?thisPositionOn66) . BIND(?this AS ?pfs1t194) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn65))) AS ?pfsb62) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn66))) AS ?pfse63) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn65, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a61')) AS ?annotation61) . BIND(?this AS ?pfs60) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch199 faldo:location ?templateMotifSequenceMatchRegionP68767200 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP68767202 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP68767MF_00181195 . ?templateMotifSequenceMatchRegionP68767200 faldo:begin ?templateMotifSequenceMatchBeginP68767201 . ?templateMotifSequenceMatchBeginP68767201 faldo:position ?templateMotifSequenceMatchBeginPositionP68767196 ; faldo:reference isoform:P68767-1 . ?templateMotifSequenceProfileAlignmentOperationP68767202 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . ?targetMotifMatch203 faldo:location ?targetMotifMatchRegionMatch204 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_00181206 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP68767MF_00181197 . ?targetMotifMatchRegionMatch204 faldo:begin ?targetMotifMatchRegionMatchBeginMF_00181205 . ?targetMotifMatchRegionMatchBeginMF_00181205 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_00181198 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_00181206 edam:has_input signature:MF_00181 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP68767MF_00181195, 1, (STRLEN(?templateMotifCigarP68767MF_00181195) - STRLEN(REPLACE(?templateMotifCigarP68767MF_00181195, CONCAT('^(?:-*[^-]){', STR(((354 - ?templateMotifSequenceMatchBeginPositionP68767196) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1207) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP68767MF_00181197, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181197) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181197, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1207), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP68767MF_00181197, 1, (STRLEN(?targetMotifMatchCigarP68767MF_00181197) - STRLEN(REPLACE(?targetMotifMatchCigarP68767MF_00181197, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1207), '}'), '')))), '[^-]', ''))) AS ?step2208) . BIND(((?step2208 + ?targetMotifMatchRegionMatchBeginPositionMF_00181198) - 1) AS ?thisPositionOn72) . BIND(?thisPositionOn72 AS ?thisPositionOn73) . BIND(?this AS ?pfs1t209) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn72))) AS ?pfsb69) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn73))) AS ?pfse70) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn72, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_00181a68')) AS ?annotation68) . BIND(?this AS ?pfs67) . } }