CONSTRUCT { _:509996 up:source unirule:MF_01409 . _:509997 up:source unirule:MF_01409 . _:509998 up:source unirule:MF_01409 . _:509999 up:source unirule:MF_01409 . _:510000 up:source unirule:MF_01409 . _:510001 up:source unirule:MF_01409 . _:510002 up:source unirule:MF_01409 . _:510003 up:source unirule:MF_01409 . _:510004 up:source unirule:MF_01409 . _:510005 up:source unirule:MF_01409 . _:510006 up:source unirule:MF_01409 . _:510007 up:source unirule:MF_01409 . _:510008 up:source unirule:MF_01409 . _:510009 up:source unirule:MF_01409 . _:510010 up:source unirule:MF_01409 . _:510011 up:source unirule:MF_01409 . _:510012 up:source unirule:MF_01409 . _:510013 up:source unirule:MF_01409 . _:510014 up:source unirule:MF_01409 . _:510015 up:source unirule:MF_01409 . _:510016 up:source unirule:MF_01409 . _:510017 up:source unirule:MF_01409 . _:510018 up:source unirule:MF_01409 . _:510019 up:source unirule:MF_01409 . _:510020 up:source unirule:MF_01409 . ?this up:annotation ?annotation1 , ?annotation2 , ?annotation4 , ?annotation5 , ?annotation6 ; up:classifiedWith GO:0003985 , GO:0019287 , keyword:12 , keyword:414 , keyword:808 ; up:recommendedName ?name0 . ?name0 up:ecName '2.3.3.10' ; up:fullName 'Hydroxymethylglutaryl-CoA synthase' ; up:shortName 'HMG-CoA synthase' , 'HMGCS' ; rdf:type up:Structured_Name . ?annotation1 a up:Function_Annotation ; rdfs:comment 'Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds that are building blocks of archaeal membrane lipids.' . ?annotation2 up:activity ?activity3 ; rdf:type up:Catalytic_Activity_Annotation . ?activity3 up:catalyticActivity <http://rdf.rhea-db.org/10188>; up:enzymeClass <http://purl.uniprot.org/enzyme/2.3.3.10>. ?annotation4 a up:Pathway_Annotation ; rdfs:comment 'Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3.' . ?annotation5 a up:Subunit_Annotation ; rdfs:comment 'Interacts with acetoacetyl-CoA thiolase that catalyzes the precedent step in the pathway and with a DUF35 protein. The acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site, which allows for efficient coupling of the endergonic thiolase reaction with the exergonic HMGCS reaction.' . ?annotation6 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the thiolase-like superfamily. Archaeal HMG-CoA synthase family.' . ?pfs7 up:annotation ?annotation8 . ?annotation8 faldo:begin ?pfsb9 ; faldo:end ?pfse10 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Proton donor/acceptor' . ?pfsb9 faldo:position ?thisPositionOn11 ; rdf:type faldo:ExactPosition . ?pfse10 faldo:position ?thisPositionOn12 ; rdf:type faldo:ExactPosition . ?pfs13 up:annotation ?annotation14 . ?annotation14 faldo:begin ?pfsb15 ; faldo:end ?pfse16 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Acyl-thioester intermediate' . ?pfsb15 faldo:position ?thisPositionOn17 ; rdf:type faldo:ExactPosition . ?pfse16 faldo:position ?thisPositionOn18 ; rdf:type faldo:ExactPosition . ?pfs19 up:annotation ?annotation20 . ?annotation20 faldo:begin ?pfsb21 ; faldo:end ?pfse22 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Proton donor/acceptor' . ?pfsb21 faldo:position ?thisPositionOn23 ; rdf:type faldo:ExactPosition . ?pfse22 faldo:position ?thisPositionOn24 ; rdf:type faldo:ExactPosition . ?pfs25 up:annotation ?annotation26 . ?annotation26 faldo:begin ?pfsb27 ; faldo:end ?pfse28 ; up:ligand ?ligand29 ; rdf:type up:Binding_Site_Annotation . ?pfsb27 faldo:position ?thisPositionOn30 ; rdf:type faldo:ExactPosition . ?pfse28 faldo:position ?thisPositionOn31 ; rdf:type faldo:ExactPosition . ?ligand29 rdfs:subClassOf chebi:43074 . ?pfs32 up:annotation ?annotation33 . ?annotation33 faldo:begin ?pfsb34 ; faldo:end ?pfse35 ; up:ligand ?ligand36 ; rdf:type up:Binding_Site_Annotation . ?pfsb34 faldo:position ?thisPositionOn37 ; rdf:type faldo:ExactPosition . ?pfse35 faldo:position ?thisPositionOn38 ; rdf:type faldo:ExactPosition . ?ligand36 rdfs:subClassOf chebi:43074 . ?pfs39 up:annotation ?annotation40 . ?annotation40 faldo:begin ?pfsb41 ; faldo:end ?pfse42 ; up:ligand ?ligand43 ; rdf:type up:Binding_Site_Annotation . ?pfsb41 faldo:position ?thisPositionOn44 ; rdf:type faldo:ExactPosition . ?pfse42 faldo:position ?thisPositionOn45 ; rdf:type faldo:ExactPosition . ?ligand43 rdfs:subClassOf chebi:43074 . ?pfs46 up:annotation ?annotation47 . ?annotation47 faldo:begin ?pfsb48 ; faldo:end ?pfse49 ; up:ligand ?ligand50 ; rdf:type up:Binding_Site_Annotation . ?pfsb48 faldo:position ?thisPositionOn51 ; rdf:type faldo:ExactPosition . ?pfse49 faldo:position ?thisPositionOn52 ; rdf:type faldo:ExactPosition . ?ligand50 rdfs:subClassOf chebi:43074 . ?pfs53 up:annotation ?annotation54 . ?annotation54 faldo:begin ?pfsb55 ; faldo:end ?pfse56 ; up:ligand ?ligand57 ; rdf:type up:Binding_Site_Annotation . ?pfsb55 faldo:position ?thisPositionOn58 ; rdf:type faldo:ExactPosition . ?pfse56 faldo:position ?thisPositionOn59 ; rdf:type faldo:ExactPosition . ?ligand57 rdfs:subClassOf chebi:57287 . ?pfs60 up:annotation ?annotation61 . ?annotation61 faldo:begin ?pfsb62 ; faldo:end ?pfse63 ; up:ligand ?ligand64 ; rdf:type up:Binding_Site_Annotation . ?pfsb62 faldo:position ?thisPositionOn65 ; rdf:type faldo:ExactPosition . ?pfse63 faldo:position ?thisPositionOn66 ; rdf:type faldo:ExactPosition . ?ligand64 rdfs:subClassOf chebi:43074 . ?pfs67 up:annotation ?annotation68 . ?annotation68 faldo:begin ?pfsb69 ; faldo:end ?pfse70 ; up:ligand ?ligand71 ; rdf:type up:Binding_Site_Annotation . ?pfsb69 faldo:position ?thisPositionOn72 ; rdf:type faldo:ExactPosition . ?pfse70 faldo:position ?thisPositionOn73 ; rdf:type faldo:ExactPosition . ?ligand71 rdfs:subClassOf chebi:43074 . ?pfs74 up:annotation ?annotation75 . ?annotation75 faldo:begin ?pfsb76 ; faldo:end ?pfse77 ; up:ligand ?ligand78 ; rdf:type up:Binding_Site_Annotation . ?pfsb76 faldo:position ?thisPositionOn79 ; rdf:type faldo:ExactPosition . ?pfse77 faldo:position ?thisPositionOn80 ; rdf:type faldo:ExactPosition . ?ligand78 rdfs:subClassOf chebi:57287 . ?pfs81 up:annotation ?annotation82 . ?annotation82 faldo:begin ?pfsb83 ; faldo:end ?pfse84 ; up:ligand ?ligand85 ; rdf:type up:Binding_Site_Annotation . ?pfsb83 faldo:position ?thisPositionOn86 ; rdf:type faldo:ExactPosition . ?pfse84 faldo:position ?thisPositionOn87 ; rdf:type faldo:ExactPosition . ?ligand85 rdfs:subClassOf chebi:43074 . ?pfs88 up:annotation ?annotation89 . ?annotation89 faldo:begin ?pfsb90 ; faldo:end ?pfse91 ; up:ligand ?ligand92 ; rdf:type up:Binding_Site_Annotation . ?pfsb90 faldo:position ?thisPositionOn93 ; rdf:type faldo:ExactPosition . ?pfse91 faldo:position ?thisPositionOn94 ; rdf:type faldo:ExactPosition . ?ligand92 rdfs:subClassOf chebi:43074 . ?pfs95 up:annotation ?annotation96 . ?annotation96 faldo:begin ?pfsb97 ; faldo:end ?pfse98 ; up:ligand ?ligand99 ; rdf:type up:Binding_Site_Annotation . ?pfsb97 faldo:position ?thisPositionOn100 ; rdf:type faldo:ExactPosition . ?pfse98 faldo:position ?thisPositionOn101 ; rdf:type faldo:ExactPosition . ?ligand99 rdfs:subClassOf chebi:43074 . _:510021 a rdf:Statement ; up:attribution _:509996 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:510022 a rdf:Statement ; up:attribution _:509997 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation1 . _:510023 a rdf:Statement ; up:attribution _:509998 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation2 . _:510024 a rdf:Statement ; up:attribution _:509999 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation4 . _:510025 a rdf:Statement ; up:attribution _:510000 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation5 . _:510026 a rdf:Statement ; up:attribution _:510001 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation6 . _:510027 a rdf:Statement ; up:attribution _:510002 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:12 . _:510028 a rdf:Statement ; up:attribution _:510003 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:414 . _:510029 a rdf:Statement ; up:attribution _:510004 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:808 . _:510030 a rdf:Statement ; up:attribution _:510005 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0003985 . _:510031 a rdf:Statement ; up:attribution _:510006 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0019287 . _:510032 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs7 ; rdf:predicate up:annotation ; rdf:object ?annotation8 . _:510033 a rdf:Statement ; up:attribution _:510007 ; rdf:subject ?pfs7 ; rdf:predicate up:annotation ; rdf:object ?annotation8 . _:510034 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs13 ; rdf:predicate up:annotation ; rdf:object ?annotation14 . _:510035 a rdf:Statement ; up:attribution _:510008 ; rdf:subject ?pfs13 ; rdf:predicate up:annotation ; rdf:object ?annotation14 . _:510036 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs19 ; rdf:predicate up:annotation ; rdf:object ?annotation20 . _:510037 a rdf:Statement ; up:attribution _:510009 ; rdf:subject ?pfs19 ; rdf:predicate up:annotation ; rdf:object ?annotation20 . _:510038 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs25 ; rdf:predicate up:annotation ; rdf:object ?annotation26 . _:510039 a rdf:Statement ; up:attribution _:510010 ; rdf:subject ?pfs25 ; rdf:predicate up:annotation ; rdf:object ?annotation26 . _:510040 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs32 ; rdf:predicate up:annotation ; rdf:object ?annotation33 . _:510041 a rdf:Statement ; up:attribution _:510011 ; rdf:subject ?pfs32 ; rdf:predicate up:annotation ; rdf:object ?annotation33 . _:510042 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs39 ; rdf:predicate up:annotation ; rdf:object ?annotation40 . _:510043 a rdf:Statement ; up:attribution _:510012 ; rdf:subject ?pfs39 ; rdf:predicate up:annotation ; rdf:object ?annotation40 . _:510044 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs46 ; rdf:predicate up:annotation ; rdf:object ?annotation47 . _:510045 a rdf:Statement ; up:attribution _:510013 ; rdf:subject ?pfs46 ; rdf:predicate up:annotation ; rdf:object ?annotation47 . _:510046 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs53 ; rdf:predicate up:annotation ; rdf:object ?annotation54 . _:510047 a rdf:Statement ; up:attribution _:510014 ; rdf:subject ?pfs53 ; rdf:predicate up:annotation ; rdf:object ?annotation54 . _:510048 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs60 ; rdf:predicate up:annotation ; rdf:object ?annotation61 . _:510049 a rdf:Statement ; up:attribution _:510015 ; rdf:subject ?pfs60 ; rdf:predicate up:annotation ; rdf:object ?annotation61 . _:510050 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs67 ; rdf:predicate up:annotation ; rdf:object ?annotation68 . _:510051 a rdf:Statement ; up:attribution _:510016 ; rdf:subject ?pfs67 ; rdf:predicate up:annotation ; rdf:object ?annotation68 . _:510052 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs74 ; rdf:predicate up:annotation ; rdf:object ?annotation75 . _:510053 a rdf:Statement ; up:attribution _:510017 ; rdf:subject ?pfs74 ; rdf:predicate up:annotation ; rdf:object ?annotation75 . _:510054 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs81 ; rdf:predicate up:annotation ; rdf:object ?annotation82 . _:510055 a rdf:Statement ; up:attribution _:510018 ; rdf:subject ?pfs81 ; rdf:predicate up:annotation ; rdf:object ?annotation82 . _:510056 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs88 ; rdf:predicate up:annotation ; rdf:object ?annotation89 . _:510057 a rdf:Statement ; up:attribution _:510019 ; rdf:subject ?pfs88 ; rdf:predicate up:annotation ; rdf:object ?annotation89 . _:510058 a rdf:Statement ; up:source unirule:MF_01409 ; rdf:subject ?pfs95 ; rdf:predicate up:annotation ; rdf:object ?annotation96 . _:510059 a rdf:Statement ; up:attribution _:510020 ; rdf:subject ?pfs95 ; rdf:predicate up:annotation ; rdf:object ?annotation96 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_01409 #Rule MF_01409 Created by:? on:2005-02-28 Modified by:Catherine Rivoire on:2024-10-31 ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_01409 . ?thisOrganism rdfs:subClassOf+ taxon:2157 . BIND(URI(CONCAT(STR(?this), '#MF_01409a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_01409a1')) AS ?annotation1) . BIND(URI(CONCAT(STR(?this), '#MF_01409a2')) AS ?annotation2) . BIND(URI(CONCAT(STR(?this), '#MF_01409a4')) AS ?annotation4) . BIND(URI(CONCAT(STR(?this), '#MF_01409a5')) AS ?annotation5) . BIND(URI(CONCAT(STR(?this), '#MF_01409a6')) AS ?annotation6) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch106 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1107 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1109 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409102 . ?templateMotifSequenceMatchRegionQ0W7K1107 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1108 . ?templateMotifSequenceMatchBeginQ0W7K1108 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1103 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1109 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch110 faldo:location ?targetMotifMatchRegionMatch111 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409113 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409104 . ?targetMotifMatchRegionMatch111 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409112 . ?targetMotifMatchRegionMatchBeginMF_01409112 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409105 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409113 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409102, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409102) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409102, CONCAT('^(?:-*[^-]){', STR(((80 - ?templateMotifSequenceMatchBeginPositionQ0W7K1103) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1114) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409104, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409104) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409104, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1114), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409104, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409104) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409104, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1114), '}'), '')))), '[^-]', ''))) AS ?step2115) . BIND(((?step2115 + ?targetMotifMatchRegionMatchBeginPositionMF_01409105) - 1) AS ?thisPositionOn11) . BIND(?thisPositionOn11 AS ?thisPositionOn12) . BIND(?this AS ?pfs1t116) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn11))) AS ?pfsb9) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn12))) AS ?pfse10) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn11, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_01409a8')) AS ?annotation8) . BIND(?this AS ?pfs7) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch121 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1122 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1124 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409117 . ?templateMotifSequenceMatchRegionQ0W7K1122 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1123 . ?templateMotifSequenceMatchBeginQ0W7K1123 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1118 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1124 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch125 faldo:location ?targetMotifMatchRegionMatch126 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409128 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409119 . ?targetMotifMatchRegionMatch126 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409127 . ?targetMotifMatchRegionMatchBeginMF_01409127 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409120 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409128 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409117, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409117) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409117, CONCAT('^(?:-*[^-]){', STR(((112 - ?templateMotifSequenceMatchBeginPositionQ0W7K1118) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1129) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409119, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409119) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409119, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1129), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409119, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409119) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409119, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1129), '}'), '')))), '[^-]', ''))) AS ?step2130) . BIND(((?step2130 + ?targetMotifMatchRegionMatchBeginPositionMF_01409120) - 1) AS ?thisPositionOn17) . BIND(?thisPositionOn17 AS ?thisPositionOn18) . BIND(?this AS ?pfs1t131) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn17))) AS ?pfsb15) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn18))) AS ?pfse16) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn17, 1) = 'C')) . BIND(URI(CONCAT(STR(?this), '#MF_01409a14')) AS ?annotation14) . BIND(?this AS ?pfs13) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch136 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1137 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1139 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409132 . ?templateMotifSequenceMatchRegionQ0W7K1137 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1138 . ?templateMotifSequenceMatchBeginQ0W7K1138 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1133 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1139 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch140 faldo:location ?targetMotifMatchRegionMatch141 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409143 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409134 . ?targetMotifMatchRegionMatch141 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409142 . ?targetMotifMatchRegionMatchBeginMF_01409142 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409135 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409143 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409132, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409132) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409132, CONCAT('^(?:-*[^-]){', STR(((234 - ?templateMotifSequenceMatchBeginPositionQ0W7K1133) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1144) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409134, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409134) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409134, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1144), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409134, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409134) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409134, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1144), '}'), '')))), '[^-]', ''))) AS ?step2145) . BIND(((?step2145 + ?targetMotifMatchRegionMatchBeginPositionMF_01409135) - 1) AS ?thisPositionOn23) . BIND(?thisPositionOn23 AS ?thisPositionOn24) . BIND(?this AS ?pfs1t146) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn23))) AS ?pfsb21) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn24))) AS ?pfse22) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn23, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_01409a20')) AS ?annotation20) . BIND(?this AS ?pfs19) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch151 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1152 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1154 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409147 . ?templateMotifSequenceMatchRegionQ0W7K1152 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1153 . ?templateMotifSequenceMatchBeginQ0W7K1153 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1148 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1154 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch155 faldo:location ?targetMotifMatchRegionMatch156 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409158 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409149 . ?targetMotifMatchRegionMatch156 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409157 . ?targetMotifMatchRegionMatchBeginMF_01409157 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409150 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409158 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409147, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409147) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409147, CONCAT('^(?:-*[^-]){', STR(((29 - ?templateMotifSequenceMatchBeginPositionQ0W7K1148) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1159) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409149, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409149) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409149, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1159), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409149, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409149) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409149, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1159), '}'), '')))), '[^-]', ''))) AS ?step2160) . BIND(((?step2160 + ?targetMotifMatchRegionMatchBeginPositionMF_01409150) - 1) AS ?thisPositionOn30) . BIND(?thisPositionOn30 AS ?thisPositionOn31) . BIND(?this AS ?pfs1t161) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn30))) AS ?pfsb27) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn31))) AS ?pfse28) . FILTER (REGEX('[DE]', SUBSTR(?thisSequenceValue, ?thisPositionOn30, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01409a26')) AS ?annotation26) . BIND(?this AS ?pfs25) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch166 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1167 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1169 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409162 . ?templateMotifSequenceMatchRegionQ0W7K1167 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1168 . ?templateMotifSequenceMatchBeginQ0W7K1168 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1163 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1169 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch170 faldo:location ?targetMotifMatchRegionMatch171 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409173 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409164 . ?targetMotifMatchRegionMatch171 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409172 . ?targetMotifMatchRegionMatchBeginMF_01409172 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409165 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409173 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409162, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409162) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409162, CONCAT('^(?:-*[^-]){', STR(((30 - ?templateMotifSequenceMatchBeginPositionQ0W7K1163) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1174) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409164, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409164) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409164, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1174), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409164, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409164) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409164, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1174), '}'), '')))), '[^-]', ''))) AS ?step2175) . BIND(((?step2175 + ?targetMotifMatchRegionMatchBeginPositionMF_01409165) - 1) AS ?thisPositionOn37) . BIND(?thisPositionOn37 AS ?thisPositionOn38) . BIND(?this AS ?pfs1t176) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn37))) AS ?pfsb34) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn38))) AS ?pfse35) . FILTER (REGEX('[AV]', SUBSTR(?thisSequenceValue, ?thisPositionOn37, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01409a33')) AS ?annotation33) . BIND(?this AS ?pfs32) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch181 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1182 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1184 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409177 . ?templateMotifSequenceMatchRegionQ0W7K1182 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1183 . ?templateMotifSequenceMatchBeginQ0W7K1183 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1178 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1184 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch185 faldo:location ?targetMotifMatchRegionMatch186 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409188 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409179 . ?targetMotifMatchRegionMatch186 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409187 . ?targetMotifMatchRegionMatchBeginMF_01409187 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409180 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409188 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409177, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409177) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409177, CONCAT('^(?:-*[^-]){', STR(((112 - ?templateMotifSequenceMatchBeginPositionQ0W7K1178) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1189) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409179, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409179) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409179, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1189), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409179, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409179) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409179, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1189), '}'), '')))), '[^-]', ''))) AS ?step2190) . BIND(((?step2190 + ?targetMotifMatchRegionMatchBeginPositionMF_01409180) - 1) AS ?thisPositionOn44) . BIND(?thisPositionOn44 AS ?thisPositionOn45) . BIND(?this AS ?pfs1t191) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn44))) AS ?pfsb41) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn45))) AS ?pfse42) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn44, 1) = 'C')) . BIND(URI(CONCAT(STR(?this), '#MF_01409a40')) AS ?annotation40) . BIND(?this AS ?pfs39) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch196 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1197 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1199 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409192 . ?templateMotifSequenceMatchRegionQ0W7K1197 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1198 . ?templateMotifSequenceMatchBeginQ0W7K1198 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1193 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1199 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch200 faldo:location ?targetMotifMatchRegionMatch201 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409203 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409194 . ?targetMotifMatchRegionMatch201 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409202 . ?targetMotifMatchRegionMatchBeginMF_01409202 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409195 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409203 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409192, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409192) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409192, CONCAT('^(?:-*[^-]){', STR(((153 - ?templateMotifSequenceMatchBeginPositionQ0W7K1193) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1204) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409194, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409194) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409194, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1204), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409194, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409194) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409194, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1204), '}'), '')))), '[^-]', ''))) AS ?step2205) . BIND(((?step2205 + ?targetMotifMatchRegionMatchBeginPositionMF_01409195) - 1) AS ?thisPositionOn51) . BIND(?thisPositionOn51 AS ?thisPositionOn52) . BIND(?this AS ?pfs1t206) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn51))) AS ?pfsb48) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn52))) AS ?pfse49) . FILTER (REGEX('[TS]', SUBSTR(?thisSequenceValue, ?thisPositionOn51, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01409a47')) AS ?annotation47) . BIND(?this AS ?pfs46) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch211 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1212 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1214 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409207 . ?templateMotifSequenceMatchRegionQ0W7K1212 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1213 . ?templateMotifSequenceMatchBeginQ0W7K1213 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1208 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1214 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch215 faldo:location ?targetMotifMatchRegionMatch216 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409218 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409209 . ?targetMotifMatchRegionMatch216 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409217 . ?targetMotifMatchRegionMatchBeginMF_01409217 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409210 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409218 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409207, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409207) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409207, CONCAT('^(?:-*[^-]){', STR(((199 - ?templateMotifSequenceMatchBeginPositionQ0W7K1208) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1219) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409209, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409209) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409209, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1219), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409209, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409209) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409209, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1219), '}'), '')))), '[^-]', ''))) AS ?step2220) . BIND(((?step2220 + ?targetMotifMatchRegionMatchBeginPositionMF_01409210) - 1) AS ?thisPositionOn58) . BIND(?thisPositionOn58 AS ?thisPositionOn59) . BIND(?this AS ?pfs1t221) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn58))) AS ?pfsb55) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn59))) AS ?pfse56) . FILTER (REGEX('[RK]', SUBSTR(?thisSequenceValue, ?thisPositionOn58, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01409a54')) AS ?annotation54) . BIND(?this AS ?pfs53) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch226 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1227 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1229 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409222 . ?templateMotifSequenceMatchRegionQ0W7K1227 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1228 . ?templateMotifSequenceMatchBeginQ0W7K1228 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1223 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1229 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch230 faldo:location ?targetMotifMatchRegionMatch231 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409233 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409224 . ?targetMotifMatchRegionMatch231 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409232 . ?targetMotifMatchRegionMatchBeginMF_01409232 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409225 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409233 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409222, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409222) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409222, CONCAT('^(?:-*[^-]){', STR(((201 - ?templateMotifSequenceMatchBeginPositionQ0W7K1223) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1234) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409224, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409224) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409224, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1234), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409224, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409224) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409224, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1234), '}'), '')))), '[^-]', ''))) AS ?step2235) . BIND(((?step2235 + ?targetMotifMatchRegionMatchBeginPositionMF_01409225) - 1) AS ?thisPositionOn65) . BIND(?thisPositionOn65 AS ?thisPositionOn66) . BIND(?this AS ?pfs1t236) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn65))) AS ?pfsb62) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn66))) AS ?pfse63) . FILTER (REGEX('[TS]', SUBSTR(?thisSequenceValue, ?thisPositionOn65, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01409a61')) AS ?annotation61) . BIND(?this AS ?pfs60) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch241 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1242 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1244 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409237 . ?templateMotifSequenceMatchRegionQ0W7K1242 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1243 . ?templateMotifSequenceMatchBeginQ0W7K1243 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1238 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1244 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch245 faldo:location ?targetMotifMatchRegionMatch246 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409248 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409239 . ?targetMotifMatchRegionMatch246 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409247 . ?targetMotifMatchRegionMatchBeginMF_01409247 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409240 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409248 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409237, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409237) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409237, CONCAT('^(?:-*[^-]){', STR(((234 - ?templateMotifSequenceMatchBeginPositionQ0W7K1238) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1249) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409239, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409239) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409239, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1249), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409239, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409239) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409239, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1249), '}'), '')))), '[^-]', ''))) AS ?step2250) . BIND(((?step2250 + ?targetMotifMatchRegionMatchBeginPositionMF_01409240) - 1) AS ?thisPositionOn72) . BIND(?thisPositionOn72 AS ?thisPositionOn73) . BIND(?this AS ?pfs1t251) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn72))) AS ?pfsb69) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn73))) AS ?pfse70) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn72, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_01409a68')) AS ?annotation68) . BIND(?this AS ?pfs67) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch256 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1257 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1259 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409252 . ?templateMotifSequenceMatchRegionQ0W7K1257 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1258 . ?templateMotifSequenceMatchBeginQ0W7K1258 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1253 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1259 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch260 faldo:location ?targetMotifMatchRegionMatch261 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409263 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409254 . ?targetMotifMatchRegionMatch261 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409262 . ?targetMotifMatchRegionMatchBeginMF_01409262 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409255 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409263 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409252, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409252) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409252, CONCAT('^(?:-*[^-]){', STR(((239 - ?templateMotifSequenceMatchBeginPositionQ0W7K1253) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1264) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409254, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409254) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409254, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1264), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409254, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409254) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409254, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1264), '}'), '')))), '[^-]', ''))) AS ?step2265) . BIND(((?step2265 + ?targetMotifMatchRegionMatchBeginPositionMF_01409255) - 1) AS ?thisPositionOn79) . BIND(?thisPositionOn79 AS ?thisPositionOn80) . BIND(?this AS ?pfs1t266) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn79))) AS ?pfsb76) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn80))) AS ?pfse77) . FILTER (REGEX('[KR]', SUBSTR(?thisSequenceValue, ?thisPositionOn79, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01409a75')) AS ?annotation75) . BIND(?this AS ?pfs74) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch271 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1272 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1274 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409267 . ?templateMotifSequenceMatchRegionQ0W7K1272 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1273 . ?templateMotifSequenceMatchBeginQ0W7K1273 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1268 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1274 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch275 faldo:location ?targetMotifMatchRegionMatch276 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409278 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409269 . ?targetMotifMatchRegionMatch276 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409277 . ?targetMotifMatchRegionMatchBeginMF_01409277 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409270 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409278 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409267, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409267) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409267, CONCAT('^(?:-*[^-]){', STR(((243 - ?templateMotifSequenceMatchBeginPositionQ0W7K1268) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1279) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409269, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409269) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409269, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1279), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409269, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409269) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409269, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1279), '}'), '')))), '[^-]', ''))) AS ?step2280) . BIND(((?step2280 + ?targetMotifMatchRegionMatchBeginPositionMF_01409270) - 1) AS ?thisPositionOn86) . BIND(?thisPositionOn86 AS ?thisPositionOn87) . BIND(?this AS ?pfs1t281) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn86))) AS ?pfsb83) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn87))) AS ?pfse84) . FILTER (REGEX('[RK]', SUBSTR(?thisSequenceValue, ?thisPositionOn86, 1))) . BIND(URI(CONCAT(STR(?this), '#MF_01409a82')) AS ?annotation82) . BIND(?this AS ?pfs81) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch286 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1287 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1289 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409282 . ?templateMotifSequenceMatchRegionQ0W7K1287 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1288 . ?templateMotifSequenceMatchBeginQ0W7K1288 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1283 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1289 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch290 faldo:location ?targetMotifMatchRegionMatch291 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409293 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409284 . ?targetMotifMatchRegionMatch291 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409292 . ?targetMotifMatchRegionMatchBeginMF_01409292 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409285 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409293 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409282, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409282) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409282, CONCAT('^(?:-*[^-]){', STR(((266 - ?templateMotifSequenceMatchBeginPositionQ0W7K1283) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1294) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409284, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409284) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409284, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1294), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409284, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409284) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409284, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1294), '}'), '')))), '[^-]', ''))) AS ?step2295) . BIND(((?step2295 + ?targetMotifMatchRegionMatchBeginPositionMF_01409285) - 1) AS ?thisPositionOn93) . BIND(?thisPositionOn93 AS ?thisPositionOn94) . BIND(?this AS ?pfs1t296) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn93))) AS ?pfsb90) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn94))) AS ?pfse91) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn93, 1) = 'N')) . BIND(URI(CONCAT(STR(?this), '#MF_01409a89')) AS ?annotation89) . BIND(?this AS ?pfs88) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch301 faldo:location ?templateMotifSequenceMatchRegionQ0W7K1302 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ0W7K1304 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ0W7K1MF_01409297 . ?templateMotifSequenceMatchRegionQ0W7K1302 faldo:begin ?templateMotifSequenceMatchBeginQ0W7K1303 . ?templateMotifSequenceMatchBeginQ0W7K1303 faldo:position ?templateMotifSequenceMatchBeginPositionQ0W7K1298 ; faldo:reference isoform:Q0W7K1-1 . ?templateMotifSequenceProfileAlignmentOperationQ0W7K1304 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . ?targetMotifMatch305 faldo:location ?targetMotifMatchRegionMatch306 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_01409308 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ0W7K1MF_01409299 . ?targetMotifMatchRegionMatch306 faldo:begin ?targetMotifMatchRegionMatchBeginMF_01409307 . ?targetMotifMatchRegionMatchBeginMF_01409307 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_01409300 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_01409308 edam:has_input signature:MF_01409 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ0W7K1MF_01409297, 1, (STRLEN(?templateMotifCigarQ0W7K1MF_01409297) - STRLEN(REPLACE(?templateMotifCigarQ0W7K1MF_01409297, CONCAT('^(?:-*[^-]){', STR(((296 - ?templateMotifSequenceMatchBeginPositionQ0W7K1298) + 1)), '}'), '')))), '[a-z]', '')) AS ?step1309) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409299, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409299) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409299, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1309), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ0W7K1MF_01409299, 1, (STRLEN(?targetMotifMatchCigarQ0W7K1MF_01409299) - STRLEN(REPLACE(?targetMotifMatchCigarQ0W7K1MF_01409299, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step1309), '}'), '')))), '[^-]', ''))) AS ?step2310) . BIND(((?step2310 + ?targetMotifMatchRegionMatchBeginPositionMF_01409300) - 1) AS ?thisPositionOn100) . BIND(?thisPositionOn100 AS ?thisPositionOn101) . BIND(?this AS ?pfs1t311) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn100))) AS ?pfsb97) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn101))) AS ?pfse98) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn100, 1) = 'S')) . BIND(URI(CONCAT(STR(?this), '#MF_01409a96')) AS ?annotation96) . BIND(?this AS ?pfs95) . } }