@prefix rdf: . @prefix rdfs: . @prefix rdf4j: . @prefix sesame: . @prefix owl: . @prefix xsd: . @prefix fn: . a , ; , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ; ; ; ; """CONSTRUCT { _:608903 up:source unirule:MF_01667 . _:608904 up:source unirule:MF_01667 . _:608905 up:source unirule:MF_01667 . _:608906 up:source unirule:MF_01667 . _:608907 up:source unirule:MF_01667 . _:608908 up:source unirule:MF_01667 . _:608909 up:source unirule:MF_01667 . _:608910 up:source unirule:MF_01667 . _:608911 up:source unirule:MF_01667 . _:608912 up:source unirule:MF_01667 . _:608913 up:source unirule:MF_01667 . _:608914 up:source unirule:MF_01667 . _:608915 up:source unirule:MF_01667 . _:608916 up:source unirule:MF_01667 . _:608917 up:source unirule:MF_01667 . _:608918 up:source unirule:MF_01667 . _:608919 up:source unirule:MF_01667 . _:608920 up:source unirule:MF_01667 . _:608921 up:source unirule:MF_01667 . ?this up:annotation ?annotation2 , ?annotation3 , ?annotation5 , ?annotation7 , ?annotation9 , ?annotation10 , ?annotation12 ; up:classifiedWith GO:0005886 , GO:0016618 , GO:0030267 , keyword:520 , keyword:521 , keyword:560 , keyword:963 ; up:recommendedName ?name0 . ?name0 up:ecName '1.1.1.79' , '1.1.1.81' ; up:fullName 'Glyoxylate/hydroxypyruvate reductase B' ; rdf:type up:Structured_Name . ?gene1 skos:prefLabel 'ghrB' . ?annotation2 a up:Function_Annotation ; rdfs:comment 'Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.' . ?annotation3 up:activity ?activity4 ; rdf:type up:Catalytic_Activity_Annotation . ?activity4 up:catalyticActivity ; up:enzymeClass . ?annotation5 up:activity ?activity6 ; rdf:type up:Catalytic_Activity_Annotation . ?activity6 up:catalyticActivity ; up:enzymeClass . ?annotation7 up:activity ?activity8 ; rdf:type up:Catalytic_Activity_Annotation . ?activity8 up:catalyticActivity ; up:enzymeClass . ?annotation9 a up:Subunit_Annotation ; rdfs:comment 'Homodimer.' . ?annotation10 a up:Subcellular_Location_Annotation . ?annotation10li11 up:cellularComponent . ?annotation12 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.' . ?pfs13 up:annotation ?annotation14 . ?annotation14 faldo:begin ?pfsb15 ; faldo:end ?pfse16 ; rdf:type up:Active_Site_Annotation . ?pfsb15 faldo:position ?thisPositionOn17 ; rdf:type faldo:ExactPosition . ?pfse16 faldo:position ?thisPositionOn18 ; rdf:type faldo:ExactPosition . ?pfs19 up:annotation ?annotation20 . ?annotation20 faldo:begin ?pfsb21 ; faldo:end ?pfse22 ; rdf:type up:Active_Site_Annotation . ?pfsb21 faldo:position ?thisPositionOn23 ; rdf:type faldo:ExactPosition . ?pfse22 faldo:position ?thisPositionOn24 ; rdf:type faldo:ExactPosition . ?pfs25 up:annotation ?annotation26 . ?annotation26 faldo:begin ?pfsb27 ; faldo:end ?pfse28 ; rdf:type up:Active_Site_Annotation ; rdfs:comment 'Proton donor' . ?pfsb27 faldo:position ?thisPositionOn29 ; rdf:type faldo:ExactPosition . ?pfse28 faldo:position ?thisPositionOn30 ; rdf:type faldo:ExactPosition . _:608922 a rdf:Statement ; up:attribution _:608903 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:608923 a rdf:Statement ; up:attribution _:608904 ; rdf:subject ?gene1 ; rdf:predicate up:encodedBy ; rdf:object ?gene1 . _:608924 a rdf:Statement ; up:attribution _:608905 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation2 . _:608925 a rdf:Statement ; up:attribution _:608906 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation3 . _:608926 a rdf:Statement ; up:attribution _:608907 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation5 . _:608927 a rdf:Statement ; up:attribution _:608908 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation7 . _:608928 a rdf:Statement ; up:attribution _:608909 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation9 . _:608929 a rdf:Statement ; up:attribution _:608910 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation10 . _:608930 a rdf:Statement ; up:attribution _:608911 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:608931 a rdf:Statement ; up:attribution _:608912 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:963 . _:608932 a rdf:Statement ; up:attribution _:608913 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:520 . _:608933 a rdf:Statement ; up:attribution _:608914 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:521 . _:608934 a rdf:Statement ; up:attribution _:608915 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:560 . _:608935 a rdf:Statement ; up:attribution _:608916 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0016618 . _:608936 a rdf:Statement ; up:attribution _:608917 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0030267 . _:608937 a rdf:Statement ; up:attribution _:608918 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0005886 . _:608938 a rdf:Statement ; up:source unirule:MF_01667 ; rdf:subject ?pfs13 ; rdf:predicate up:annotation ; rdf:object ?annotation14 . _:608939 a rdf:Statement ; up:attribution _:608919 ; rdf:subject ?pfs13 ; rdf:predicate up:annotation ; rdf:object ?annotation14 . _:608940 a rdf:Statement ; up:source unirule:MF_01667 ; rdf:subject ?pfs19 ; rdf:predicate up:annotation ; rdf:object ?annotation20 . _:608941 a rdf:Statement ; up:attribution _:608920 ; rdf:subject ?pfs19 ; rdf:predicate up:annotation ; rdf:object ?annotation20 . _:608942 a rdf:Statement ; up:source unirule:MF_01667 ; rdf:subject ?pfs25 ; rdf:predicate up:annotation ; rdf:object ?annotation26 . _:608943 a rdf:Statement ; up:attribution _:608921 ; rdf:subject ?pfs25 ; rdf:predicate up:annotation ; rdf:object ?annotation26 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_01667 #Rule MF_01667 Created by:? on:2008-08-05 Modified by:Edouard de Castro on:2024-09-03 ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_01667 . ?thisOrganism rdfs:subClassOf+ taxon:91347 . BIND(URI(CONCAT(STR(?this), '#MF_01667a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_01667a2')) AS ?annotation2) . BIND(URI(CONCAT(STR(?this), '#MF_01667a3')) AS ?annotation3) . BIND(URI(CONCAT(STR(?this), '#MF_01667a5')) AS ?annotation5) . BIND(URI(CONCAT(STR(?this), '#MF_01667a7')) AS ?annotation7) . BIND(URI(CONCAT(STR(?this), '#MF_01667a9')) AS ?annotation9) . BIND(URI(CONCAT(STR(?this), '#MF_01667a10')) AS ?annotation10) . BIND(URI(CONCAT(STR(?this), '#MF_01667a12')) AS ?annotation12) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch35 faldo:location ?templateMotifSequenceMatchRegionP3766636 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP3766638 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP37666MF_0166731 . ?templateMotifSequenceMatchRegionP3766636 faldo:begin ?templateMotifSequenceMatchBeginP3766637 . ?templateMotifSequenceMatchBeginP3766637 faldo:position ?templateMotifSequenceMatchBeginPositionP3766632 ; faldo:reference isoform:P37666-1 . ?templateMotifSequenceProfileAlignmentOperationP3766638 edam:has_input signature:MF_01667 ; rdf:type edam:operation_0300 . ?targetMotifMatch39 faldo:location ?targetMotifMatchRegionMatch40 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0166742 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP37666MF_0166733 . ?targetMotifMatchRegionMatch40 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0166741 . ?targetMotifMatchRegionMatchBeginMF_0166741 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0166734 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0166742 edam:has_input signature:MF_01667 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP37666MF_0166731, 1, (STRLEN(?templateMotifCigarP37666MF_0166731) - STRLEN(REPLACE(?templateMotifCigarP37666MF_0166731, CONCAT('^(?:-*[^-]){', STR(((237 - ?templateMotifSequenceMatchBeginPositionP3766632) + 1)), '}'), '')))), '[a-z]', '')) AS ?step143) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP37666MF_0166733, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166733) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166733, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP37666MF_0166733, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166733) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166733, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), '')))), '[^-]', ''))) AS ?step244) . BIND(((?step244 + ?targetMotifMatchRegionMatchBeginPositionMF_0166734) - 1) AS ?thisPositionOn17) . BIND(?thisPositionOn17 AS ?thisPositionOn18) . BIND(?this AS ?pfs1t45) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn17))) AS ?pfsb15) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn18))) AS ?pfse16) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn17, 1) = 'R')) . BIND(URI(CONCAT(STR(?this), '#MF_01667a14')) AS ?annotation14) . BIND(?this AS ?pfs13) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch50 faldo:location ?templateMotifSequenceMatchRegionP3766651 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP3766653 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP37666MF_0166746 . ?templateMotifSequenceMatchRegionP3766651 faldo:begin ?templateMotifSequenceMatchBeginP3766652 . ?templateMotifSequenceMatchBeginP3766652 faldo:position ?templateMotifSequenceMatchBeginPositionP3766647 ; faldo:reference isoform:P37666-1 . ?templateMotifSequenceProfileAlignmentOperationP3766653 edam:has_input signature:MF_01667 ; rdf:type edam:operation_0300 . ?targetMotifMatch54 faldo:location ?targetMotifMatchRegionMatch55 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0166757 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP37666MF_0166748 . ?targetMotifMatchRegionMatch55 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0166756 . ?targetMotifMatchRegionMatchBeginMF_0166756 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0166749 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0166757 edam:has_input signature:MF_01667 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP37666MF_0166746, 1, (STRLEN(?templateMotifCigarP37666MF_0166746) - STRLEN(REPLACE(?templateMotifCigarP37666MF_0166746, CONCAT('^(?:-*[^-]){', STR(((266 - ?templateMotifSequenceMatchBeginPositionP3766647) + 1)), '}'), '')))), '[a-z]', '')) AS ?step158) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP37666MF_0166748, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166748) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166748, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step158), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP37666MF_0166748, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166748) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166748, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step158), '}'), '')))), '[^-]', ''))) AS ?step259) . BIND(((?step259 + ?targetMotifMatchRegionMatchBeginPositionMF_0166749) - 1) AS ?thisPositionOn23) . BIND(?thisPositionOn23 AS ?thisPositionOn24) . BIND(?this AS ?pfs1t60) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn23))) AS ?pfsb21) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn24))) AS ?pfse22) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn23, 1) = 'E')) . BIND(URI(CONCAT(STR(?this), '#MF_01667a20')) AS ?annotation20) . BIND(?this AS ?pfs19) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch65 faldo:location ?templateMotifSequenceMatchRegionP3766666 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP3766668 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarP37666MF_0166761 . ?templateMotifSequenceMatchRegionP3766666 faldo:begin ?templateMotifSequenceMatchBeginP3766667 . ?templateMotifSequenceMatchBeginP3766667 faldo:position ?templateMotifSequenceMatchBeginPositionP3766662 ; faldo:reference isoform:P37666-1 . ?templateMotifSequenceProfileAlignmentOperationP3766668 edam:has_input signature:MF_01667 ; rdf:type edam:operation_0300 . ?targetMotifMatch69 faldo:location ?targetMotifMatchRegionMatch70 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0166772 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarP37666MF_0166763 . ?targetMotifMatchRegionMatch70 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0166771 . ?targetMotifMatchRegionMatchBeginMF_0166771 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0166764 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0166772 edam:has_input signature:MF_01667 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP37666MF_0166761, 1, (STRLEN(?templateMotifCigarP37666MF_0166761) - STRLEN(REPLACE(?templateMotifCigarP37666MF_0166761, CONCAT('^(?:-*[^-]){', STR(((285 - ?templateMotifSequenceMatchBeginPositionP3766662) + 1)), '}'), '')))), '[a-z]', '')) AS ?step173) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP37666MF_0166763, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166763) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166763, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step173), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP37666MF_0166763, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166763) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166763, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step173), '}'), '')))), '[^-]', ''))) AS ?step274) . BIND(((?step274 + ?targetMotifMatchRegionMatchBeginPositionMF_0166764) - 1) AS ?thisPositionOn29) . BIND(?thisPositionOn29 AS ?thisPositionOn30) . BIND(?this AS ?pfs1t75) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn29))) AS ?pfsb27) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn30))) AS ?pfse28) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn29, 1) = 'H')) . BIND(URI(CONCAT(STR(?this), '#MF_01667a26')) AS ?annotation26) . BIND(?this AS ?pfs25) . } } """ . .