@prefix rdf: . @prefix rdfs: . @prefix rdf4j: . @prefix sesame: . @prefix owl: . @prefix xsd: . @prefix fn: . a , ; , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ; ; ; ; """CONSTRUCT { _:705491 up:source unirule:MF_02005 . _:705492 up:source unirule:MF_02005 . _:705493 up:source unirule:MF_02005 . _:705494 up:source unirule:MF_02005 . _:705495 up:source unirule:MF_02005 . _:705496 up:source unirule:MF_02005 . _:705497 up:source unirule:MF_02005 . _:705498 up:source unirule:MF_02005 . _:705499 up:source unirule:MF_02005 . _:705500 up:source unirule:MF_02005 . _:705501 up:source unirule:MF_02005 . _:705502 up:source unirule:MF_02005 . _:705503 up:source unirule:MF_02005 . _:705504 up:source unirule:MF_02005 . _:705505 up:source unirule:MF_02005 . _:705506 up:source unirule:MF_02005 . _:705507 up:source unirule:MF_02005 . _:705508 up:source unirule:MF_02005 . _:705509 up:source unirule:MF_02005 . _:705510 up:source unirule:MF_02005 . _:705511 up:source unirule:MF_02005 . ?this up:alternativeName ?name1 ; up:annotation ?annotation3 , ?annotation4 , ?annotation6 , ?annotation8 , ?annotation9 ; up:classifiedWith GO:0004832 , GO:0005524 , GO:0005737 , GO:0006438 , keyword:30 , keyword:436 , keyword:547 , keyword:648 , keyword:67 , keyword:963 ; up:recommendedName ?name0 . ?name0 up:ecName '6.1.1.9' ; up:fullName 'Valine--tRNA ligase' ; rdf:type up:Structured_Name . ?name1 up:fullName 'Valyl-tRNA synthetase' ; up:shortName 'ValRS' ; rdf:type up:Structured_Name . ?gene2 skos:prefLabel 'valS' . ?annotation3 a up:Function_Annotation ; rdfs:comment \"Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.\" . ?annotation4 up:activity ?activity5 ; rdf:type up:Catalytic_Activity_Annotation . ?activity5 up:catalyticActivity ; up:enzymeClass . ?annotation6 a up:Subcellular_Location_Annotation . ?annotation6li7 up:cellularComponent . ?annotation8 a up:Domain_Annotation ; rdfs:comment 'ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.' . ?annotation9 a up:Similarity_Annotation ; rdfs:comment 'Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.' . ?pfs11 up:annotation ?annotation12 . ?annotation12 faldo:begin ?pfsb13 ; faldo:end ?pfse14 ; rdf:type up:Motif_Annotation ; rdfs:comment \"'HIGH' region\" . ?pfsb13 faldo:position ?thisPositionOn15 ; rdf:type faldo:ExactPosition . ?pfse14 faldo:position ?thisPositionOn16 ; rdf:type faldo:ExactPosition . ?pfs17 up:annotation ?annotation18 . ?annotation18 faldo:begin ?pfsb19 ; faldo:end ?pfse20 ; rdf:type up:Motif_Annotation ; rdfs:comment \"'KMSKS' region\" . ?pfsb19 faldo:position ?thisPositionOn21 ; rdf:type faldo:ExactPosition . ?pfse20 faldo:position ?thisPositionOn22 ; rdf:type faldo:ExactPosition . ?pfs23 up:annotation ?annotation24 . ?annotation24 faldo:begin ?pfsb25 ; faldo:end ?pfse26 ; up:ligand ?ligand27 ; rdf:type up:Binding_Site_Annotation . ?pfsb25 faldo:position ?thisPositionOn28 ; rdf:type faldo:ExactPosition . ?pfse26 faldo:position ?thisPositionOn29 ; rdf:type faldo:ExactPosition . ?ligand27 rdfs:subClassOf chebi:30616 . _:705512 a rdf:Statement ; up:attribution _:705491 ; rdf:subject ?this ; rdf:predicate up:recommendedName ; rdf:object ?name0 . _:705513 a rdf:Statement ; up:attribution _:705492 ; rdf:subject ?this ; rdf:predicate up:alternativeName ; rdf:object ?name1 . _:705514 a rdf:Statement ; up:attribution _:705493 ; rdf:subject ?gene2 ; rdf:predicate up:encodedBy ; rdf:object ?gene2 . _:705515 a rdf:Statement ; up:attribution _:705494 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation3 . _:705516 a rdf:Statement ; up:attribution _:705495 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation4 . _:705517 a rdf:Statement ; up:attribution _:705496 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation6 . _:705518 a rdf:Statement ; up:attribution _:705497 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation8 . _:705519 a rdf:Statement ; up:attribution _:705498 ; rdf:subject ?this ; rdf:predicate up:annotation ; rdf:object ?annotation9 . _:705520 a rdf:Statement ; up:attribution _:705499 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:963 . _:705521 a rdf:Statement ; up:attribution _:705500 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:30 . _:705522 a rdf:Statement ; up:attribution _:705501 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:67 . _:705523 a rdf:Statement ; up:attribution _:705502 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:436 . _:705524 a rdf:Statement ; up:attribution _:705503 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:547 . _:705525 a rdf:Statement ; up:attribution _:705504 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object keyword:648 . _:705526 a rdf:Statement ; up:attribution _:705505 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0004832 . _:705527 a rdf:Statement ; up:attribution _:705506 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0005524 . _:705528 a rdf:Statement ; up:attribution _:705507 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0006438 . _:705529 a rdf:Statement ; up:attribution _:705508 ; rdf:subject ?this ; rdf:predicate up:classifiedWith ; rdf:object GO:0005737 . _:705530 a rdf:Statement ; up:source unirule:MF_02005 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:705531 a rdf:Statement ; up:attribution _:705509 ; rdf:subject ?pfs11 ; rdf:predicate up:annotation ; rdf:object ?annotation12 . _:705532 a rdf:Statement ; up:source unirule:MF_02005 ; rdf:subject ?pfs17 ; rdf:predicate up:annotation ; rdf:object ?annotation18 . _:705533 a rdf:Statement ; up:attribution _:705510 ; rdf:subject ?pfs17 ; rdf:predicate up:annotation ; rdf:object ?annotation18 . _:705534 a rdf:Statement ; up:source unirule:MF_02005 ; rdf:subject ?pfs23 ; rdf:predicate up:annotation ; rdf:object ?annotation24 . _:705535 a rdf:Statement ; up:attribution _:705511 ; rdf:subject ?pfs23 ; rdf:predicate up:annotation ; rdf:object ?annotation24 . } WHERE { #baseURI: http://purl.uniprot.org/unirule/MF_02005 #Rule MF_02005 Created by:? on:2006-02-07 Modified by:Edouard de Castro on:2024-09-03 VALUES ?supertaxon30 {taxon:201174 taxon:766 taxon:2157} ?this up:organism ?thisOrganism ; rdfs:seeAlso signature:MF_02005 . ?thisOrganism rdfs:subClassOf+ ?supertaxon30 . BIND(URI(CONCAT(STR(?this), '#MF_02005a0')) AS ?name0) . BIND(URI(CONCAT(STR(?this), '#MF_02005a1')) AS ?name1) . BIND(URI(CONCAT(STR(?this), '#MF_02005a3')) AS ?annotation3) . BIND(URI(CONCAT(STR(?this), '#MF_02005a4')) AS ?annotation4) . BIND(URI(CONCAT(STR(?this), '#MF_02005a6')) AS ?annotation6) . BIND(URI(CONCAT(STR(?this), '#MF_02005a8')) AS ?annotation8) . BIND(URI(CONCAT(STR(?this), '#MF_02005a9')) AS ?annotation9) . OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch35 faldo:location ?templateMotifSequenceMatchRegionQ9ZCN636 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9ZCN638 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9ZCN6MF_0200531 . ?templateMotifSequenceMatchRegionQ9ZCN636 faldo:begin ?templateMotifSequenceMatchBeginQ9ZCN637 . ?templateMotifSequenceMatchBeginQ9ZCN637 faldo:position ?templateMotifSequenceMatchBeginPositionQ9ZCN632 ; faldo:reference isoform:Q9ZCN6-1 . ?templateMotifSequenceProfileAlignmentOperationQ9ZCN638 edam:has_input signature:MF_02005 ; rdf:type edam:operation_0300 . ?targetMotifMatch39 faldo:location ?targetMotifMatchRegionMatch40 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0200542 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9ZCN6MF_0200533 . ?targetMotifMatchRegionMatch40 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0200541 . ?targetMotifMatchRegionMatchBeginMF_0200541 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0200534 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0200542 edam:has_input signature:MF_02005 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200531, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200531) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200531, CONCAT('^(?:-*[^-]){', STR(((46 - ?templateMotifSequenceMatchBeginPositionQ9ZCN632) + 1)), '}'), '')))), '[a-z]', '')) AS ?step143) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200533, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200533) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200533, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200533, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200533) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200533, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), '')))), '[^-]', ''))) AS ?step244) . BIND(((?step244 + ?targetMotifMatchRegionMatchBeginPositionMF_0200534) - 1) AS ?thisPositionOn15) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200531, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200531) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200531, CONCAT('^(?:-*[^-]){', STR(((56 - ?templateMotifSequenceMatchBeginPositionQ9ZCN632) + 1)), '}'), '')))), '[a-z]', '')) AS ?step145) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200533, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200533) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200533, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step145), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200533, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200533) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200533, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step145), '}'), '')))), '[^-]', ''))) AS ?step246) . BIND(((?step246 + ?targetMotifMatchRegionMatchBeginPositionMF_0200534) - 1) AS ?thisPositionOn16) . BIND(?this AS ?pfs1t47) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfsb13) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn16))) AS ?pfse14) . FILTER (REGEX('P[TYF][ARNDCQEGHILKMFPSTWYVBZJUOX][STA]G[ARNDCQEGHILKMFPSTWYVBZJUOX][ARNDCQEGHILKMFPSTWYVBZJUOX]H[ILMVP]G[HN]', SUBSTR(?thisSequenceValue, ?thisPositionOn15, (?thisPositionOn16 - ?thisPositionOn15)))) . BIND(URI(CONCAT(STR(?this), '#MF_02005a12')) AS ?annotation12) . BIND(?this AS ?pfs11) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch52 faldo:location ?templateMotifSequenceMatchRegionQ9ZCN653 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9ZCN655 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9ZCN6MF_0200548 . ?templateMotifSequenceMatchRegionQ9ZCN653 faldo:begin ?templateMotifSequenceMatchBeginQ9ZCN654 . ?templateMotifSequenceMatchBeginQ9ZCN654 faldo:position ?templateMotifSequenceMatchBeginPositionQ9ZCN649 ; faldo:reference isoform:Q9ZCN6-1 . ?templateMotifSequenceProfileAlignmentOperationQ9ZCN655 edam:has_input signature:MF_02005 ; rdf:type edam:operation_0300 . ?targetMotifMatch56 faldo:location ?targetMotifMatchRegionMatch57 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0200559 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9ZCN6MF_0200550 . ?targetMotifMatchRegionMatch57 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0200558 . ?targetMotifMatchRegionMatchBeginMF_0200558 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0200551 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0200559 edam:has_input signature:MF_02005 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200548, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200548) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200548, CONCAT('^(?:-*[^-]){', STR(((536 - ?templateMotifSequenceMatchBeginPositionQ9ZCN649) + 1)), '}'), '')))), '[a-z]', '')) AS ?step160) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200550, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200550) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200550, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step160), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200550, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200550) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200550, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step160), '}'), '')))), '[^-]', ''))) AS ?step261) . BIND(((?step261 + ?targetMotifMatchRegionMatchBeginPositionMF_0200551) - 1) AS ?thisPositionOn21) . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200548, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200548) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200548, CONCAT('^(?:-*[^-]){', STR(((540 - ?templateMotifSequenceMatchBeginPositionQ9ZCN649) + 1)), '}'), '')))), '[a-z]', '')) AS ?step162) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200550, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200550) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200550, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step162), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200550, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200550) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200550, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step162), '}'), '')))), '[^-]', ''))) AS ?step263) . BIND(((?step263 + ?targetMotifMatchRegionMatchBeginPositionMF_0200551) - 1) AS ?thisPositionOn22) . BIND(?this AS ?pfs1t64) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfsb19) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfse20) . FILTER (REGEX('[KRA]MSKS', SUBSTR(?thisSequenceValue, ?thisPositionOn21, (?thisPositionOn22 - ?thisPositionOn21)))) . BIND(URI(CONCAT(STR(?this), '#MF_02005a18')) AS ?annotation18) . BIND(?this AS ?pfs17) . } OPTIONAL { ?this up:sequence ?thisSequence . ?thisSequence rdf:value ?thisSequenceValue . ?templateMotifMatch69 faldo:location ?templateMotifSequenceMatchRegionQ9ZCN670 ; edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9ZCN672 ; rdf:type edam:data_0869 ; rdf:value ?templateMotifCigarQ9ZCN6MF_0200565 . ?templateMotifSequenceMatchRegionQ9ZCN670 faldo:begin ?templateMotifSequenceMatchBeginQ9ZCN671 . ?templateMotifSequenceMatchBeginQ9ZCN671 faldo:position ?templateMotifSequenceMatchBeginPositionQ9ZCN666 ; faldo:reference isoform:Q9ZCN6-1 . ?templateMotifSequenceProfileAlignmentOperationQ9ZCN672 edam:has_input signature:MF_02005 ; rdf:type edam:operation_0300 . ?targetMotifMatch73 faldo:location ?targetMotifMatchRegionMatch74 ; edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0200576 ; rdf:type edam:data_0869 ; rdf:value ?targetMotifMatchCigarQ9ZCN6MF_0200567 . ?targetMotifMatchRegionMatch74 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0200575 . ?targetMotifMatchRegionMatchBeginMF_0200575 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0200568 ; faldo:reference ?thisSequence . ?targetMotifSequenceAlignmentOperationMF_0200576 edam:has_input signature:MF_02005 ; rdf:type edam:operation_0300 . BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200565, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200565) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200565, CONCAT('^(?:-*[^-]){', STR(((539 - ?templateMotifSequenceMatchBeginPositionQ9ZCN666) + 1)), '}'), '')))), '[a-z]', '')) AS ?step177) . BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200567, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200567) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200567, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step177), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200567, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200567) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200567, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step177), '}'), '')))), '[^-]', ''))) AS ?step278) . BIND(((?step278 + ?targetMotifMatchRegionMatchBeginPositionMF_0200568) - 1) AS ?thisPositionOn28) . BIND(?thisPositionOn28 AS ?thisPositionOn29) . BIND(?this AS ?pfs1t79) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfsb25) . BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn29))) AS ?pfse26) . FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn28, 1) = 'K')) . BIND(URI(CONCAT(STR(?this), '#MF_02005a24')) AS ?annotation24) . BIND(?this AS ?pfs23) . } OPTIONAL { ?this a up:Protein . ?this up:organism ?thisOrganism . ?thisOrganism rdfs:subClassOf+ taxon:2 . BIND(?this AS ?case10) . } } """ . .