AC   MF_00047;
DC   Protein; auto
TR   HAMAP; MF_00047; -; 1; level=0
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Names: Dala_Dala_lig
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ID   DDL
DE   RecName: Full=D-alanine--D-alanine ligase;
DE            EC=6.3.2.4;
DE   AltName: Full=D-Ala-D-Ala ligase;
DE   AltName: Full=D-alanylalanine synthetase;
GN   Name=ddl;
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CC   -!- FUNCTION: Cell wall formation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) +
CC         phosphate; Xref=Rhea:RHEA:11224, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:57416,
CC         ChEBI:CHEBI:57822, ChEBI:CHEBI:456216; EC=6.3.2.4;
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the D-alanine--D-alanine ligase family.
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DR   Pfam; PF07478; Dala_Dala_lig_C; 1; trigger=no
DR   Pfam; PF01820; Dala_Dala_lig_N; 1; trigger=no
DR   NCBIfam; TIGR01205; D_ala_D_alaTIGR; 1; trigger=no
DR   PROSITE; PS00843; DALA_DALA_LIGASE_1; 1; trigger=no
DR   PROSITE; PS00844; DALA_DALA_LIGASE_2; 1; trigger=no
DR   PROSITE; PS50975; ATP_GRASP; 1; trigger=yes
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KW   Cell shape
KW   Cell wall biogenesis/degradation
KW   Cytoplasm
KW   Ligase
KW   Peptidoglycan synthesis
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GO   GO:0008716; F:D-alanine-D-alanine ligase activity
GO   GO:0009252; P:peptidoglycan biosynthetic process
GO   GO:0005737; C:cytoplasm
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FT   None
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Size: 291-396;
Related: None;
Template: P07862; P0A6J8;
Scope:
 Bacteria
Fusion:
 Nter: MF_00046 (murC)
 Cter: None
Duplicate: in BACCR, BRADU, BRUME, BRUSU, CHRVO, CLOPE, CLOTE, ECOLI, PSEAE,
 PSEPK, PSESM, RHILO, SALTI, SALTY, SHIFL, XANCP
Plasmid: None
Comments: Short BACSU, but does not seem to be extendable
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# Revision 1.35 2023/06/01
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