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HAMAP rule MF_01658

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General rule information [?]

Accession MF_01658
Dates 7-MAY-2008 (Created)
26-JAN-2023 (Last updated, Version 18)
Name COQ7
Scope(s) Bacteria
Pseudomonadota
Template(s) Q9I5R6 (COQ7_PSEAE); Q2RNK3 (COQ7_RHORT); [ Recover all ]
Triggered by
case c? <OC:Pseudomonadota>
HAMAP; MF_01658 (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier COQ7
Protein name RecName: Full=3-demethoxyubiquinol 3-hydroxylase;
                 Short=DMQ hydroxylase;
                 EC=1.14.99.60;
AltName: Full=2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase;
Gene name Name=coq7;

Comments [?]

FUNCTIONCatalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
CATALYTIC ACTIVITY Reaction=a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O; Xref=Rhea:RHEA:50908, Rhea:RHEA-COMP:10859, Rhea:RHEA-COMP:10914, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:17499, ChEBI:CHEBI:84167, ChEBI:CHEBI:84422; EC=1.14.99.60;
COFACTOR Name=Fe cation; Xref=ChEBI:CHEBI:24875; Note=Binds 2 iron ions per subunit.;
PATHWAYCofactor biosynthesis; ubiquinone biosynthesis.
SUBCELLULAR LOCATIONCell membrane; Peripheral membrane protein.
SIMILARITYBelongs to the COQ7 family.

Keywords [?]


Gene Ontology [?]

GO:0006744; Biological process:ubiquinone biosynthetic process
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF03232; COQ7; 1;

Features [?]

From: COQ7_PSEAE (Q9I5R6)
Key From To Description Tag Condition FTGroup
BINDING 64 64 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
E
BINDING 94 94 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
E
BINDING 94 94 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="2"
E
BINDING 97 97 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
H
BINDING 146 146 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="2"
E
BINDING 178 178 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
E
BINDING 178 178 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="2"
E
BINDING 181 181 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="2"
H

Additional information [?]

Size range 160-250 amino acids
Related rules None
Fusion Nter: None Cter: None



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