AC   MF_01681;
DC   Protein; auto
TR   HAMAP; MF_01681; -; 1; level=0
XX
Names: Salvage_MtnC
XX
ID   MTNC
DE   RecName: Full=Enolase-phosphatase E1;
DE            EC=3.1.3.77;
DE   AltName: Full=2,3-diketo-5-methylthio-1-phosphopentane phosphatase;
GN   Name=mtnC;
XX
CC   -!- FUNCTION: Bifunctional enzyme that catalyzes the enolization of 2,3-
CC       diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the
CC       intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-
CC       MTPenyl-1-P), which is then dephosphorylated to form the acireductone
CC       1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-
CC         dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate;
CC         Xref=Rhea:RHEA:21700, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:49252, ChEBI:CHEBI:58828; EC=3.1.3.77;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC       Note=Binds 1 Mg(2+) ion per subunit.;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via salvage
CC       pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate:
CC       step 3/6.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via salvage
CC       pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate:
CC       step 4/6.
CC   -!- SUBUNIT: Monomer.
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC
CC       family.
XX
DR   Pfam; PF00702; Hydrolase; 1; trigger=no
DR   PRINTS; PR00413; HADHALOGNASE; 1; trigger=no
DR   NCBIfam; TIGR01691; Enolase-ppase; 1; trigger=no
DR   NCBIfam; TIGR01549; HAD-SF-IA-v1; 1; trigger=no
DR   NCBIfam; TIGR01509; HAD-SF-IA-v3; 1; trigger=no
XX
KW   Amino-acid biosynthesis
KW   Hydrolase
KW   Magnesium
KW   Metal-binding
KW   Methionine biosynthesis
XX
GO   GO:0000287; F:magnesium ion binding
GO   GO:0043715; F:2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
GO   GO:0043716; F:2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
GO   GO:0019284; P:L-methionine salvage from S-adenosylmethionine
XX
Size: 221-253;
Related: None;
Template: P0C8L5;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.16 2023/06/01
//