AC   MF_01810;
DC   Protein; auto
TR   HAMAP; MF_01810; -; 1; level=0
XX
Names: YidC_type1
XX
ID   YIDC
DE   RecName: Full=Membrane protein insertase YidC;
DE   AltName: Full=Foldase YidC;
DE   AltName: Full=Membrane protein YidC;
DE   AltName: Full=Membrane integrase YidC;
GN   Name=yidC;
XX
CC   -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC       complex formation of integral membrane proteins into the membrane.
CC       Involved in integration of membrane proteins that insert both
CC       dependently and independently of the Sec translocase complex, as well
CC       as at least some lipoproteins. Aids folding of multispanning membrane
CC       proteins.
case <OC:Cyanobacteriota> and not <OC:Gloeobacter>
CC   -!- FUNCTION: Probably also aids protein insertion, folding and/or assembly
CC       of membrane complexes destined for the thylakoid.
end case
CC   -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC       Specifically interacts with transmembrane segments of nascent integral
CC       membrane proteins during membrane integration.
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
end case
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
XX
DR   Pfam; PF02096; 60KD_IMP; 1; trigger=no
DR   PRINTS; PR00701; 60KDINNERMP; 1; trigger=no
DR   NCBIfam; TIGR03593; YidC_nterm; 1; trigger=no
DR   NCBIfam; TIGR03592; YidC_oxa1_C; 1; trigger=no
DR   General; Transmembrane; -; 4-8; trigger=yes
XX
KW   Chaperone
KW   Membrane
KW   Protein transport
KW   Transmembrane
KW   Transport
KW   Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Transmembrane helix
XX
GO   GO:0005886; C:plasma membrane
XX
FT   None
XX
case <OC:Clostridia> or <OC:Fusobacterium>
Size: 206-465;
else
Size: 310-795;
end case
Related: MF_01811!;
Template: P25714; P74155;
Scope:
 Bacteria
Fusion:
 Nter: <PDZ/DHR>
 Cter: None
Duplicate: None
Plasmid: None
Comments: N-terminal PDZ/DHR fused in RHOBA. TIGR03593 describes a large N-
 terminal domain of unknown function not found in all members. In most
 Bacillota (MF_01811), this protein is much shorter and is probably a
 lipoprotein. Chlamydiota have been annotated as lipoproteins. Streptomyces
 seem to only have 3 transmembrane helices.
XX
# Revision 1.30 2023/06/01
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