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HAMAP rule MF_04019

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General rule information [?]

Accession MF_04019
Dates 4-APR-2016 (Created)
20-NOV-2019 (Last updated, Version 5)
Name HSV_TRX2
Scope(s) Viruses
Herpesviridae
Template(s) P10202 (TRX2_HHV11); [ Recover all ]
Triggered by HAMAP; MF_04019 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TRX2
Protein name RecName: Full=Triplex capsid protein 2;
Gene name Name=TRX2;

Comments [?]

FUNCTIONStructural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
SUBUNITInteracts with TRX1 and major capisd protein/MCP.
SUBCELLULAR LOCATIONVirion. Host nucleus.
SIMILARITYBelongs to the herpesviridae TRX2 protein family.

Keywords [?]


Gene Ontology [?]

GO:0042025; Cellular component:host cell nucleus
GO:0019028; Cellular component:viral capsid
GO:0019069; Biological process:viral capsid assembly

Cross-references [?]

Pfam PF01802; Herpes_V23; 1;

Features [?]


Additional information [?]

Size range 292-321 amino acids
Related rules None
Fusion Nter: None Cter: None



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