HAMAP

Subject	Predicate	Object
http://purl.uniprot.org/unirules/MF_00953#construct-template-44	http://spinrdf.org/sp#subject	http://purl.uniprot.org/unirules/MF_00953#construct-var-3
http://purl.uniprot.org/unirules/MF_00953#construct-template-44	http://spinrdf.org/sp#predicate	http://www.w3.org/2000/01/rdf-schema#comment
http://purl.uniprot.org/unirules/MF_00953#construct-template-44	http://spinrdf.org/sp#object	"Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone."xsd:string
http://purl.uniprot.org/unirules/MF_00953#construct	https://hamap.expasy.org/rdf/vocab#addsTriple	http://purl.uniprot.org/unirules/MF_00953#construct-template-44
http://purl.uniprot.org/unirules/MF_00953#construct-template-list-44	http://www.w3.org/1999/02/22-rdf-syntax-ns#first	http://purl.uniprot.org/unirules/MF_00953#construct-template-44

Results