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http://purl.uniprot.org/unirules/MF_04004#construct-template-69http://spinrdf.org/sp#subjecthttp://purl.uniprot.org/unirules/MF_04004#construct-var-2
http://purl.uniprot.org/unirules/MF_04004#construct-template-69http://spinrdf.org/sp#predicatehttp://www.w3.org/2000/01/rdf-schema#comment
http://purl.uniprot.org/unirules/MF_04004#construct-template-69http://spinrdf.org/sp#object"Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta)."xsd:string
http://purl.uniprot.org/unirules/MF_04004#constructhttps://hamap.expasy.org/rdf/vocab#addsTriplehttp://purl.uniprot.org/unirules/MF_04004#construct-template-69
http://purl.uniprot.org/unirules/MF_04004#construct-template-list-69http://www.w3.org/1999/02/22-rdf-syntax-ns#firsthttp://purl.uniprot.org/unirules/MF_04004#construct-template-69