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Subject | Predicate | Object |
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http://purl.uniprot.org/unirules/MF_04166#construct-template-67 | http://spinrdf.org/sp#subject | http://purl.uniprot.org/unirules/MF_04166#construct-var-4 |
http://purl.uniprot.org/unirules/MF_04166#construct-template-67 | http://spinrdf.org/sp#predicate | http://www.w3.org/2000/01/rdf-schema#comment |
http://purl.uniprot.org/unirules/MF_04166#construct-template-67 | http://spinrdf.org/sp#object | "Involved in the synthesis of the atypical nucleotide dZTP (2-amino-2'-deoxyadenosine-5'-triphosphate). Catalyzes the condensation of aspartate with deoxyguanylate into dSMP (N6-succino-2-amino-2'-deoxyadenylate), which undergoes defumarylation and phosphorylation respectively by host PurB and guanylate/nucleoside diphosphate kinases to give dZTP. dZTP is integrated into the viral genome instead of adenine by the viral DNA polymerase. This Z-base probably completely replaces adenosine and forms a triple bond to the opposite T-base. The resulting non-standard viral DNA is called Z-genome. The chemically modified DNA is probably harder for the host bacteria to digest with nucleases or restriction enzymes."xsd:string |
http://purl.uniprot.org/unirules/MF_04166#construct | https://hamap.expasy.org/rdf/vocab#addsTriple | http://purl.uniprot.org/unirules/MF_04166#construct-template-67 |
http://purl.uniprot.org/unirules/MF_04166#construct-template-list-67 | http://www.w3.org/1999/02/22-rdf-syntax-ns#first | http://purl.uniprot.org/unirules/MF_04166#construct-template-67 |