| http://purl.uniprot.org/unirules/MF_00241#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:101457 up:source unirule:MF_00241 .
_:101458 up:ecName '3.2.2.-' ;
up:fullName '8-oxoguanine DNA glycosylase' ;
up:shortName '8-oxoG DNA glycosylase' ;
rdf:type up:Structured_Name .
_:101459 up:source unirule:MF_00241 .
_:101460 up:ecName '4.2.99.18' ;
up:fullName 'DNA-(apurinic or apyrimidinic site) lyase' ;
up:shortName 'AP lyase' ;
rdf:type up:Structured_Name .
_:101461 up:source unirule:MF_00241 .
_:101462 up:source unirule:MF_00241 .
_:101463 up:source unirule:MF_00241 .
_:101464 up:source unirule:MF_00241 .
_:101465 up:source unirule:MF_00241 .
_:101466 up:source unirule:MF_00241 .
_:101467 up:source unirule:MF_00241 .
_:101468 up:source unirule:MF_00241 .
_:101469 up:source unirule:MF_00241 .
_:101470 up:source unirule:MF_00241 .
_:101471 up:source unirule:MF_00241 .
_:101472 up:source unirule:MF_00241 .
_:101473 up:source unirule:MF_00241 .
_:101474 up:source unirule:MF_00241 .
_:101475 up:source unirule:MF_00241 .
_:101476 up:source unirule:MF_00241 .
_:101477 up:source unirule:MF_00241 .
?this up:annotation ?annotation4 ,
?annotation5 ,
?annotation7 ;
up:classifiedWith GO:0003906 ,
GO:0006284 ,
GO:0016799 ,
keyword:227 ,
keyword:234 ,
keyword:326 ,
keyword:378 ,
keyword:456 ,
keyword:511 ;
up:domain ?namedpart1 ,
?namedpart2 ;
up:recommendedName ?name0 .
?name0 up:fullName '8-oxoguanine DNA glycosylase/AP lyase' ;
rdf:type up:Structured_Name .
?namedpart1 up:recommendedName _:101458 .
?namedpart2 up:recommendedName _:101460 .
?gene3 skos:prefLabel 'ogg' .
?annotation4 a up:Function_Annotation ;
rdfs:comment 'Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).' .
?annotation5 up:activity ?activity6 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity6 up:catalyticActivity ;
up:enzymeClass .
?annotation7 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the type-2 OGG1 family.' .
?pfs8 up:annotation ?annotation9 .
?annotation9 faldo:begin ?pfsb10 ;
faldo:end ?pfse11 ;
rdf:type up:Active_Site_Annotation .
?pfsb10 faldo:position ?thisPositionOn12 ;
rdf:type faldo:ExactPosition .
?pfse11 faldo:position ?thisPositionOn13 ;
rdf:type faldo:ExactPosition .
?pfs14 up:annotation ?annotation15 .
?annotation15 faldo:begin ?pfsb16 ;
faldo:end ?pfse17 ;
rdf:type up:Active_Site_Annotation .
?pfsb16 faldo:position ?thisPositionOn18 ;
rdf:type faldo:ExactPosition .
?pfse17 faldo:position ?thisPositionOn19 ;
rdf:type faldo:ExactPosition .
?pfs20 up:annotation ?annotation21 .
?annotation21 faldo:begin ?pfsb22 ;
faldo:end ?pfse23 ;
rdf:type up:Site_Annotation ;
rdfs:comment 'Important for guanine/8-oxoguanine distinction' .
?pfsb22 faldo:position ?thisPositionOn24 ;
rdf:type faldo:ExactPosition .
?pfse23 faldo:position ?thisPositionOn25 ;
rdf:type faldo:ExactPosition .
_:101478 a rdf:Statement ;
up:attribution _:101457 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:101479 a rdf:Statement ;
up:attribution _:101459 ;
rdf:subject ?this ;
rdf:predicate up:domain ;
rdf:object ?namedpart1 .
_:101480 a rdf:Statement ;
up:attribution _:101461 ;
rdf:subject ?this ;
rdf:predicate up:domain ;
rdf:object ?namedpart2 .
_:101481 a rdf:Statement ;
up:attribution _:101462 ;
rdf:subject ?gene3 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene3 .
_:101482 a rdf:Statement ;
up:attribution _:101463 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation4 .
_:101483 a rdf:Statement ;
up:attribution _:101464 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation5 .
_:101484 a rdf:Statement ;
up:attribution _:101465 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation7 .
_:101485 a rdf:Statement ;
up:attribution _:101466 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:227 .
_:101486 a rdf:Statement ;
up:attribution _:101467 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:234 .
_:101487 a rdf:Statement ;
up:attribution _:101468 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:326 .
_:101488 a rdf:Statement ;
up:attribution _:101469 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:378 .
_:101489 a rdf:Statement ;
up:attribution _:101470 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:456 .
_:101490 a rdf:Statement ;
up:attribution _:101471 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:511 .
_:101491 a rdf:Statement ;
up:attribution _:101472 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0003906 .
_:101492 a rdf:Statement ;
up:attribution _:101473 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0016799 .
_:101493 a rdf:Statement ;
up:attribution _:101474 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0006284 .
_:101494 a rdf:Statement ;
up:source unirule:MF_00241 ;
rdf:subject ?pfs8 ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:101495 a rdf:Statement ;
up:attribution _:101475 ;
rdf:subject ?pfs8 ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:101496 a rdf:Statement ;
up:source unirule:MF_00241 ;
rdf:subject ?pfs14 ;
rdf:predicate up:annotation ;
rdf:object ?annotation15 .
_:101497 a rdf:Statement ;
up:attribution _:101476 ;
rdf:subject ?pfs14 ;
rdf:predicate up:annotation ;
rdf:object ?annotation15 .
_:101498 a rdf:Statement ;
up:source unirule:MF_00241 ;
rdf:subject ?pfs20 ;
rdf:predicate up:annotation ;
rdf:object ?annotation21 .
_:101499 a rdf:Statement ;
up:attribution _:101477 ;
rdf:subject ?pfs20 ;
rdf:predicate up:annotation ;
rdf:object ?annotation21 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_00241
#Rule MF_00241 Created by:? on:2005-02-28 Modified by:Elisabeth Coudert on:2024-01-30
VALUES ?supertaxon26 {taxon:2 taxon:2157}
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_00241 .
?thisOrganism rdfs:subClassOf+ ?supertaxon26 .
BIND(URI(CONCAT(STR(?this), '#MF_00241a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_00241a1')) AS ?namedpart1) .
BIND(URI(CONCAT(STR(?this), '#MF_00241a2')) AS ?namedpart2) .
BIND(URI(CONCAT(STR(?this), '#MF_00241a4')) AS ?annotation4) .
BIND(URI(CONCAT(STR(?this), '#MF_00241a5')) AS ?annotation5) .
BIND(URI(CONCAT(STR(?this), '#MF_00241a7')) AS ?annotation7) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch31 faldo:location ?templateMotifSequenceMatchRegionQ5813432 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5813434 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ58134MF_0024127 .
?templateMotifSequenceMatchRegionQ5813432 faldo:begin ?templateMotifSequenceMatchBeginQ5813433 .
?templateMotifSequenceMatchBeginQ5813433 faldo:position ?templateMotifSequenceMatchBeginPositionQ5813428 ;
faldo:reference isoform:Q58134-1 .
?templateMotifSequenceProfileAlignmentOperationQ5813434 edam:has_input signature:MF_00241 ;
rdf:type edam:operation_0300 .
?targetMotifMatch35 faldo:location ?targetMotifMatchRegionMatch36 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0024138 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ58134MF_0024129 .
?targetMotifMatchRegionMatch36 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0024137 .
?targetMotifMatchRegionMatchBeginMF_0024137 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0024130 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0024138 edam:has_input signature:MF_00241 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ58134MF_0024127, 1, (STRLEN(?templateMotifCigarQ58134MF_0024127) - STRLEN(REPLACE(?templateMotifCigarQ58134MF_0024127, CONCAT('^(?:-*[^-]){', STR(((129 - ?templateMotifSequenceMatchBeginPositionQ5813428) + 1)), '}'), '')))), '[a-z]', '')) AS ?step139) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ58134MF_0024129, 1, (STRLEN(?targetMotifMatchCigarQ58134MF_0024129) - STRLEN(REPLACE(?targetMotifMatchCigarQ58134MF_0024129, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step139), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ58134MF_0024129, 1, (STRLEN(?targetMotifMatchCigarQ58134MF_0024129) - STRLEN(REPLACE(?targetMotifMatchCigarQ58134MF_0024129, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step139), '}'), '')))), '[^-]', ''))) AS ?step240) .
BIND(((?step240 + ?targetMotifMatchRegionMatchBeginPositionMF_0024130) - 1) AS ?thisPositionOn12) .
BIND(?thisPositionOn12 AS ?thisPositionOn13) .
BIND(?this AS ?pfs1t41) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn12))) AS ?pfsb10) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn13))) AS ?pfse11) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn12, 1) = 'K')) .
BIND(URI(CONCAT(STR(?this), '#MF_00241a9')) AS ?annotation9) .
BIND(?this AS ?pfs8) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch46 faldo:location ?templateMotifSequenceMatchRegionQ5813447 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5813449 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ58134MF_0024142 .
?templateMotifSequenceMatchRegionQ5813447 faldo:begin ?templateMotifSequenceMatchBeginQ5813448 .
?templateMotifSequenceMatchBeginQ5813448 faldo:position ?templateMotifSequenceMatchBeginPositionQ5813443 ;
faldo:reference isoform:Q58134-1 .
?templateMotifSequenceProfileAlignmentOperationQ5813449 edam:has_input signature:MF_00241 ;
rdf:type edam:operation_0300 .
?targetMotifMatch50 faldo:location ?targetMotifMatchRegionMatch51 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0024153 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ58134MF_0024144 .
?targetMotifMatchRegionMatch51 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0024152 .
?targetMotifMatchRegionMatchBeginMF_0024152 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0024145 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0024153 edam:has_input signature:MF_00241 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ58134MF_0024142, 1, (STRLEN(?templateMotifCigarQ58134MF_0024142) - STRLEN(REPLACE(?templateMotifCigarQ58134MF_0024142, CONCAT('^(?:-*[^-]){', STR(((147 - ?templateMotifSequenceMatchBeginPositionQ5813443) + 1)), '}'), '')))), '[a-z]', '')) AS ?step154) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ58134MF_0024144, 1, (STRLEN(?targetMotifMatchCigarQ58134MF_0024144) - STRLEN(REPLACE(?targetMotifMatchCigarQ58134MF_0024144, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step154), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ58134MF_0024144, 1, (STRLEN(?targetMotifMatchCigarQ58134MF_0024144) - STRLEN(REPLACE(?targetMotifMatchCigarQ58134MF_0024144, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step154), '}'), '')))), '[^-]', ''))) AS ?step255) .
BIND(((?step255 + ?targetMotifMatchRegionMatchBeginPositionMF_0024145) - 1) AS ?thisPositionOn18) .
BIND(?thisPositionOn18 AS ?thisPositionOn19) .
BIND(?this AS ?pfs1t56) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn18))) AS ?pfsb16) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn19))) AS ?pfse17) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn18, 1) = 'D')) .
BIND(URI(CONCAT(STR(?this), '#MF_00241a15')) AS ?annotation15) .
BIND(?this AS ?pfs14) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch61 faldo:location ?templateMotifSequenceMatchRegionQ5813462 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5813464 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ58134MF_0024157 .
?templateMotifSequenceMatchRegionQ5813462 faldo:begin ?templateMotifSequenceMatchBeginQ5813463 .
?templateMotifSequenceMatchBeginQ5813463 faldo:position ?templateMotifSequenceMatchBeginPositionQ5813458 ;
faldo:reference isoform:Q58134-1 .
?templateMotifSequenceProfileAlignmentOperationQ5813464 edam:has_input signature:MF_00241 ;
rdf:type edam:operation_0300 .
?targetMotifMatch65 faldo:location ?targetMotifMatchRegionMatch66 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0024168 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ58134MF_0024159 .
?targetMotifMatchRegionMatch66 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0024167 .
?targetMotifMatchRegionMatchBeginMF_0024167 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0024160 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0024168 edam:has_input signature:MF_00241 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(?thisSequenceValue) AS ?thisPositionOn24) .
BIND(?thisPositionOn24 AS ?thisPositionOn25) .
BIND(?this AS ?pfs1t69) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn24))) AS ?pfsb22) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn25))) AS ?pfse23) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn24, 1) = 'K')) .
BIND(URI(CONCAT(STR(?this), '#MF_00241a21')) AS ?annotation21) .
BIND(?this AS ?pfs20) .
}
}
"xsd:string |
