| http://purl.uniprot.org/unirules/MF_01163#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:405738 up:source unirule:MF_01163 .
_:405739 up:source unirule:MF_01163 .
_:405740 up:source unirule:MF_01163 .
_:405741 up:source unirule:MF_01163 .
_:405742 up:source unirule:MF_01163 .
_:405743 up:source unirule:MF_01163 .
_:405744 up:source unirule:MF_01163 .
_:405745 up:source unirule:MF_01163 .
_:405746 up:source unirule:MF_01163 .
_:405747 up:source unirule:MF_01163 .
_:405748 up:source unirule:MF_01163 .
_:405749 up:source unirule:MF_01163 .
_:405750 up:source unirule:MF_01163 .
_:405751 up:source unirule:MF_01163 .
_:405752 up:source unirule:MF_01163 .
_:405753 up:source unirule:MF_01163 .
_:405754 up:source unirule:MF_01163 .
?this up:alternativeName ?name1 ;
up:annotation ?annotation3 ,
?annotation4 ,
?annotation6 ,
?annotation7 ;
up:classifiedWith GO:0006189 ,
GO:0016879 ,
keyword:436 ,
keyword:547 ,
keyword:658 ,
keyword:67 ;
up:recommendedName ?name0 .
?name0 up:ecName '6.3.4.23' ;
up:fullName "5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase" ;
rdf:type up:Structured_Name .
?name1 up:fullName "5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase" ;
rdf:type up:Structured_Name .
?gene2 skos:prefLabel 'purP' .
?annotation3 a up:Function_Annotation ;
rdfs:comment "Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates." .
?annotation4 up:activity ?activity5 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity5 up:catalyticActivity ;
up:enzymeClass .
?annotation6 a up:Pathway_Annotation ;
rdfs:comment 'Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (formate route): step 1/1.' .
?annotation7 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the phosphohexose mutase family.' .
?pfs8 up:annotation ?annotation9 .
?annotation9 faldo:begin ?pfsb10 ;
faldo:end ?pfse11 ;
up:ligand ?ligand12 ;
rdf:type up:Binding_Site_Annotation .
?pfsb10 faldo:position ?thisPositionOn13 ;
rdf:type faldo:ExactPosition .
?pfse11 faldo:position ?thisPositionOn14 ;
rdf:type faldo:ExactPosition .
?ligand12 rdfs:subClassOf chebi:30616 .
?pfs15 up:annotation ?annotation16 .
?annotation16 faldo:begin ?pfsb17 ;
faldo:end ?pfse18 ;
up:ligand ?ligand19 ;
rdf:type up:Binding_Site_Annotation .
?pfsb17 faldo:position ?thisPositionOn20 ;
rdf:type faldo:ExactPosition .
?pfse18 faldo:position ?thisPositionOn21 ;
rdf:type faldo:ExactPosition .
?ligand19 rdfs:subClassOf chebi:58475 .
?pfs22 up:annotation ?annotation23 .
?annotation23 faldo:begin ?pfsb24 ;
faldo:end ?pfse25 ;
up:ligand ?ligand26 ;
rdf:type up:Binding_Site_Annotation .
?pfsb24 faldo:position ?thisPositionOn27 ;
rdf:type faldo:ExactPosition .
?pfse25 faldo:position ?thisPositionOn28 ;
rdf:type faldo:ExactPosition .
?ligand26 rdfs:subClassOf chebi:58475 .
?pfs29 up:annotation ?annotation30 .
?annotation30 faldo:begin ?pfsb31 ;
faldo:end ?pfse32 ;
up:ligand ?ligand33 ;
rdf:type up:Binding_Site_Annotation .
?pfsb31 faldo:position ?thisPositionOn34 ;
rdf:type faldo:ExactPosition .
?pfse32 faldo:position ?thisPositionOn35 ;
rdf:type faldo:ExactPosition .
?ligand33 rdfs:subClassOf chebi:58475 .
_:405755 a rdf:Statement ;
up:attribution _:405738 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:405756 a rdf:Statement ;
up:attribution _:405739 ;
rdf:subject ?this ;
rdf:predicate up:alternativeName ;
rdf:object ?name1 .
_:405757 a rdf:Statement ;
up:attribution _:405740 ;
rdf:subject ?gene2 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene2 .
_:405758 a rdf:Statement ;
up:attribution _:405741 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:405759 a rdf:Statement ;
up:attribution _:405742 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation4 .
_:405760 a rdf:Statement ;
up:attribution _:405743 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation6 .
_:405761 a rdf:Statement ;
up:attribution _:405744 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation7 .
_:405762 a rdf:Statement ;
up:attribution _:405745 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:67 .
_:405763 a rdf:Statement ;
up:attribution _:405746 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:436 .
_:405764 a rdf:Statement ;
up:attribution _:405747 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:547 .
_:405765 a rdf:Statement ;
up:attribution _:405748 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:658 .
_:405766 a rdf:Statement ;
up:attribution _:405749 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0016879 .
_:405767 a rdf:Statement ;
up:attribution _:405750 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0006189 .
_:405768 a rdf:Statement ;
up:source unirule:MF_01163 ;
rdf:subject ?pfs8 ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:405769 a rdf:Statement ;
up:attribution _:405751 ;
rdf:subject ?pfs8 ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:405770 a rdf:Statement ;
up:source unirule:MF_01163 ;
rdf:subject ?pfs15 ;
rdf:predicate up:annotation ;
rdf:object ?annotation16 .
_:405771 a rdf:Statement ;
up:attribution _:405752 ;
rdf:subject ?pfs15 ;
rdf:predicate up:annotation ;
rdf:object ?annotation16 .
_:405772 a rdf:Statement ;
up:source unirule:MF_01163 ;
rdf:subject ?pfs22 ;
rdf:predicate up:annotation ;
rdf:object ?annotation23 .
_:405773 a rdf:Statement ;
up:attribution _:405753 ;
rdf:subject ?pfs22 ;
rdf:predicate up:annotation ;
rdf:object ?annotation23 .
_:405774 a rdf:Statement ;
up:source unirule:MF_01163 ;
rdf:subject ?pfs29 ;
rdf:predicate up:annotation ;
rdf:object ?annotation30 .
_:405775 a rdf:Statement ;
up:attribution _:405754 ;
rdf:subject ?pfs29 ;
rdf:predicate up:annotation ;
rdf:object ?annotation30 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_01163
#Rule MF_01163 Created by:? on:2005-04-12 Modified by:Edouard de Castro on:2024-09-03
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_01163 .
?thisOrganism rdfs:subClassOf+ taxon:2157 .
BIND(URI(CONCAT(STR(?this), '#MF_01163a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a1')) AS ?name1) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a4')) AS ?annotation4) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a6')) AS ?annotation6) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a7')) AS ?annotation7) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch40 faldo:location ?templateMotifSequenceMatchRegionQ8U0R741 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ8U0R743 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ8U0R7MF_0116336 .
?templateMotifSequenceMatchRegionQ8U0R741 faldo:begin ?templateMotifSequenceMatchBeginQ8U0R742 .
?templateMotifSequenceMatchBeginQ8U0R742 faldo:position ?templateMotifSequenceMatchBeginPositionQ8U0R737 ;
faldo:reference isoform:Q8U0R7-1 .
?templateMotifSequenceProfileAlignmentOperationQ8U0R743 edam:has_input signature:MF_01163 ;
rdf:type edam:operation_0300 .
?targetMotifMatch44 faldo:location ?targetMotifMatchRegionMatch45 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0116347 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ8U0R7MF_0116338 .
?targetMotifMatchRegionMatch45 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0116346 .
?targetMotifMatchRegionMatchBeginMF_0116346 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0116339 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0116347 edam:has_input signature:MF_01163 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ8U0R7MF_0116336, 1, (STRLEN(?templateMotifCigarQ8U0R7MF_0116336) - STRLEN(REPLACE(?templateMotifCigarQ8U0R7MF_0116336, CONCAT('^(?:-*[^-]){', STR(((204 - ?templateMotifSequenceMatchBeginPositionQ8U0R737) + 1)), '}'), '')))), '[a-z]', '')) AS ?step148) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ8U0R7MF_0116338, 1, (STRLEN(?targetMotifMatchCigarQ8U0R7MF_0116338) - STRLEN(REPLACE(?targetMotifMatchCigarQ8U0R7MF_0116338, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step148), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ8U0R7MF_0116338, 1, (STRLEN(?targetMotifMatchCigarQ8U0R7MF_0116338) - STRLEN(REPLACE(?targetMotifMatchCigarQ8U0R7MF_0116338, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step148), '}'), '')))), '[^-]', ''))) AS ?step249) .
BIND(((?step249 + ?targetMotifMatchRegionMatchBeginPositionMF_0116339) - 1) AS ?thisPositionOn13) .
BIND(?thisPositionOn13 AS ?thisPositionOn14) .
BIND(?this AS ?pfs1t50) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn13))) AS ?pfsb10) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn14))) AS ?pfse11) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn13, 1) = 'E')) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a9')) AS ?annotation9) .
BIND(?this AS ?pfs8) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch55 faldo:location ?templateMotifSequenceMatchRegionQ8U0R756 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ8U0R758 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ8U0R7MF_0116351 .
?templateMotifSequenceMatchRegionQ8U0R756 faldo:begin ?templateMotifSequenceMatchBeginQ8U0R757 .
?templateMotifSequenceMatchBeginQ8U0R757 faldo:position ?templateMotifSequenceMatchBeginPositionQ8U0R752 ;
faldo:reference isoform:Q8U0R7-1 .
?templateMotifSequenceProfileAlignmentOperationQ8U0R758 edam:has_input signature:MF_01163 ;
rdf:type edam:operation_0300 .
?targetMotifMatch59 faldo:location ?targetMotifMatchRegionMatch60 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0116362 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ8U0R7MF_0116353 .
?targetMotifMatchRegionMatch60 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0116361 .
?targetMotifMatchRegionMatchBeginMF_0116361 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0116354 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0116362 edam:has_input signature:MF_01163 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ8U0R7MF_0116351, 1, (STRLEN(?templateMotifCigarQ8U0R7MF_0116351) - STRLEN(REPLACE(?templateMotifCigarQ8U0R7MF_0116351, CONCAT('^(?:-*[^-]){', STR(((11 - ?templateMotifSequenceMatchBeginPositionQ8U0R752) + 1)), '}'), '')))), '[a-z]', '')) AS ?step163) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ8U0R7MF_0116353, 1, (STRLEN(?targetMotifMatchCigarQ8U0R7MF_0116353) - STRLEN(REPLACE(?targetMotifMatchCigarQ8U0R7MF_0116353, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step163), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ8U0R7MF_0116353, 1, (STRLEN(?targetMotifMatchCigarQ8U0R7MF_0116353) - STRLEN(REPLACE(?targetMotifMatchCigarQ8U0R7MF_0116353, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step163), '}'), '')))), '[^-]', ''))) AS ?step264) .
BIND(((?step264 + ?targetMotifMatchRegionMatchBeginPositionMF_0116354) - 1) AS ?thisPositionOn20) .
BIND(?thisPositionOn20 AS ?thisPositionOn21) .
BIND(?this AS ?pfs1t65) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn20))) AS ?pfsb17) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfse18) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn20, 1) = 'H')) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a16')) AS ?annotation16) .
BIND(?this AS ?pfs15) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch70 faldo:location ?templateMotifSequenceMatchRegionQ8U0R771 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ8U0R773 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ8U0R7MF_0116366 .
?templateMotifSequenceMatchRegionQ8U0R771 faldo:begin ?templateMotifSequenceMatchBeginQ8U0R772 .
?templateMotifSequenceMatchBeginQ8U0R772 faldo:position ?templateMotifSequenceMatchBeginPositionQ8U0R767 ;
faldo:reference isoform:Q8U0R7-1 .
?templateMotifSequenceProfileAlignmentOperationQ8U0R773 edam:has_input signature:MF_01163 ;
rdf:type edam:operation_0300 .
?targetMotifMatch74 faldo:location ?targetMotifMatchRegionMatch75 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0116377 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ8U0R7MF_0116368 .
?targetMotifMatchRegionMatch75 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0116376 .
?targetMotifMatchRegionMatchBeginMF_0116376 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0116369 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0116377 edam:has_input signature:MF_01163 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ8U0R7MF_0116366, 1, (STRLEN(?templateMotifCigarQ8U0R7MF_0116366) - STRLEN(REPLACE(?templateMotifCigarQ8U0R7MF_0116366, CONCAT('^(?:-*[^-]){', STR(((71 - ?templateMotifSequenceMatchBeginPositionQ8U0R767) + 1)), '}'), '')))), '[a-z]', '')) AS ?step178) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ8U0R7MF_0116368, 1, (STRLEN(?targetMotifMatchCigarQ8U0R7MF_0116368) - STRLEN(REPLACE(?targetMotifMatchCigarQ8U0R7MF_0116368, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step178), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ8U0R7MF_0116368, 1, (STRLEN(?targetMotifMatchCigarQ8U0R7MF_0116368) - STRLEN(REPLACE(?targetMotifMatchCigarQ8U0R7MF_0116368, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step178), '}'), '')))), '[^-]', ''))) AS ?step279) .
BIND(((?step279 + ?targetMotifMatchRegionMatchBeginPositionMF_0116369) - 1) AS ?thisPositionOn27) .
BIND(?thisPositionOn27 AS ?thisPositionOn28) .
BIND(?this AS ?pfs1t80) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn27))) AS ?pfsb24) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfse25) .
FILTER (REGEX('[ST]', SUBSTR(?thisSequenceValue, ?thisPositionOn27, 1))) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a23')) AS ?annotation23) .
BIND(?this AS ?pfs22) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch85 faldo:location ?templateMotifSequenceMatchRegionQ8U0R786 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ8U0R788 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ8U0R7MF_0116381 .
?templateMotifSequenceMatchRegionQ8U0R786 faldo:begin ?templateMotifSequenceMatchBeginQ8U0R787 .
?templateMotifSequenceMatchBeginQ8U0R787 faldo:position ?templateMotifSequenceMatchBeginPositionQ8U0R782 ;
faldo:reference isoform:Q8U0R7-1 .
?templateMotifSequenceProfileAlignmentOperationQ8U0R788 edam:has_input signature:MF_01163 ;
rdf:type edam:operation_0300 .
?targetMotifMatch89 faldo:location ?targetMotifMatchRegionMatch90 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0116392 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ8U0R7MF_0116383 .
?targetMotifMatchRegionMatch90 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0116391 .
?targetMotifMatchRegionMatchBeginMF_0116391 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0116384 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0116392 edam:has_input signature:MF_01163 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ8U0R7MF_0116381, 1, (STRLEN(?templateMotifCigarQ8U0R7MF_0116381) - STRLEN(REPLACE(?templateMotifCigarQ8U0R7MF_0116381, CONCAT('^(?:-*[^-]){', STR(((232 - ?templateMotifSequenceMatchBeginPositionQ8U0R782) + 1)), '}'), '')))), '[a-z]', '')) AS ?step193) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ8U0R7MF_0116383, 1, (STRLEN(?targetMotifMatchCigarQ8U0R7MF_0116383) - STRLEN(REPLACE(?targetMotifMatchCigarQ8U0R7MF_0116383, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step193), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ8U0R7MF_0116383, 1, (STRLEN(?targetMotifMatchCigarQ8U0R7MF_0116383) - STRLEN(REPLACE(?targetMotifMatchCigarQ8U0R7MF_0116383, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step193), '}'), '')))), '[^-]', ''))) AS ?step294) .
BIND(((?step294 + ?targetMotifMatchRegionMatchBeginPositionMF_0116384) - 1) AS ?thisPositionOn34) .
BIND(?thisPositionOn34 AS ?thisPositionOn35) .
BIND(?this AS ?pfs1t95) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn34))) AS ?pfsb31) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn35))) AS ?pfse32) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn34, 1) = 'N')) .
BIND(URI(CONCAT(STR(?this), '#MF_01163a30')) AS ?annotation30) .
BIND(?this AS ?pfs29) .
}
}
"xsd:string |